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Journal articles on the topic 'Antitussive'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

KOLOSOVA, N. G., and S. I. SHATALINA. "ANTITUSSIVE DRUGS IN CHILDREN’S PRACTICE." Medical Council, no. 9 (July 18, 2017): 76–79. http://dx.doi.org/10.21518/2079-701x-2017-9-76-79.

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Adequate choice and use of antitussive therapy in pediatrics presupposes knowing at least the two key aspects: causes of cough and the specific mechanism of the cough reflex in children, as well as the mechanisms of action of antitussive drugs used. The need for the treatment of cough as such, that is, prescription of the so-called antitussive drugs, arises mainly in children with nonproductive, dry, persistent cough. Central antitussives suppress the function of the cough center in the medulla oblongata or other associated nerve centers of the brain. The antitussive drug butamirate, often use

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2

Prasanna K, Thomas, Jog Pramod, Vohra Nitin R, Veligandla Krishna C, and Petare Uttam Anup. "A Newer Approach in the Management of Cough: A Review on Levodropropizine." Journal of Respiratory Diseases 1, no. 3 (2023): 1–14. http://dx.doi.org/10.14302/issn.2642-9241.jrd-23-4566.

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Safe and effective antitussive therapy remains a significant area of unmet need for cough management. Antitussive drugs are commonly used cough suppressants and include centrally acting (opioids and non-opioids) cough suppressants and peripherally acting antitussives. Authors searched PubMed, Google Scholar and additional studies from reference lists via cross-referencing to identify studies assessing levodropropizine for the treatment of cough. Of the 748 studies identified, 13 were included. Recent clinical evidence, guideline recommendations and findings from this review suggest that levodr

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3

Mizushima, Yutaka, Atsushi Hirata, Tooru Hori, Shigeki Sawazaki, Eiji Sugiyama, and Masashi Kobayashi. "Antitussive Effect of Herbal Medicine Bakumondo-to: A Case Report." American Journal of Chinese Medicine 24, no. 03n04 (1996): 321–25. http://dx.doi.org/10.1142/s0192415x96000384.

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A 50 year-old woman with progressive systemic sclerosis accompanied by interstitial pneumonia complained of a dry cough. A variety of antitussive agents were given for the dry cough over a one year period, but her symptoms continued. However, when a herbal medicine Bakumondo-to was administered, her intractable dry cough subsided dramatically within 10 days. Bakumondo-to may be a good antitussive agent for interstitial pneumonia associated with a dry cough that is resistant to other antitussives.

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4

BERKHOUT, C. "ABSENCE DE PREUVE D EFFICACITE CLINIQUE DE L OXOMEMAZINE DANS LA TOUX." EXERCER 36, no. 211 (2025): 122–23. https://doi.org/10.56746/exercer.2025.211.122.

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Publication originale de T. Bacon, C. Blanchard, E. Dubois, H. Vaillant-Roussel H, R. Boussageon (Collège universitaire de médecine générale de Lyon) La toux est un motif fréquent de consultation en médecine générale (MG). L’oxomémazine (Toplexil®) est un antitussif de la famille des antihistaminiques. C’est la spécialité antitussive la plus prescrite en France, responsable en 2022 d’un coût de remboursement pour l’Assurance maladie de 1 724 227 €. La Haute Autorité de santé n’accorde à l’oxomémazine qu’un faible service médical rendu (SMR) et une absence d’amélioration du service médical rend

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5

Robab, Sana, and Nida Saleem. "Search for the Natural Remedies for the Treatment of Dry Cough." Phytopharmacological Communications 3, no. 2 (2023): 125–43. http://dx.doi.org/10.55627/ppc.003.02.0386.

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Cough, also known as tussis, is a normal physiological response to any intrusion in the airway. However, this protective mechanism can turn into a nuisance if it becomes persistent, significantly impacting the social, physical, and psychological performance of a person. Standard antitussive agents like dextromethorphan (DXM), codeine, and gabapentin produce various side effects, and in some cases, cough relapse occurs as soon as drug doses are reduced. In search of better alternatives, this article delves into plant-based antitussive agents, studied in-vivo in various cough models. The cough m

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6

Kumar, Manoj, and Shweta Parihar. "A Literature Review on Herbs used in Cough Medication." Scholars Academic Journal of Pharmacy 11, no. 9 (2022): 125–32. http://dx.doi.org/10.36347/sajp.2022.v11i09.001.

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Cough refers to a powerful explosive expiration that clears the tracheobronchial tract of fluids and foreign materials. Given the high frequency of cough in both children and adults, the goal of this review paper was to document the plants used to cure and relieve cough in traditional culture and ethnobotany. The issues arising from the use of traditional opioid antitussive medications, such as codeine and codeine-like compounds, to treat cough in a variety of respiratory disorders. Medicinal plants have the potential to provide compounds with strong antitussive efficacy and little side effect

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7

Muralinath, E., Devi Pooja, Chbukdhara Prasanta, et al. "Understanding the Mechanism of Action of Antitussive Drugs." Journal of Advances in Experimental Therapeutics and Neurotherapeutics 2, no. 1 (2024): 17–20. https://doi.org/10.5281/zenodo.10795828.

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<em>Coughing is a natural reflex that assists in clearing the airways of irritants and mucus. Opioid have been used as an effective antitussive compounds namely codeine and hydro condone are helpful in stopping coughing in a wide manner. By binding with mu Opioid receptors, opioid ms stop the release of neurotransmitters particularly participated I'm the cough reflex and decrease the urge to cough. Dextro methorphin ( DXM) is a non_ Opioid derivative that participates in the over the counter cough medications. If performs centrally by blocking N_ methyl_D_ asparate (NMDA) receptors and stoppin

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8

Yang, Seonkyeong, Juan M. Hincapie-Castillo, Xuehua Ke, et al. "Evaluation of Cough Medication Use Patterns in Ambulatory Care Settings in the United States: 2003–2018." Journal of Clinical Medicine 11, no. 13 (2022): 3671. http://dx.doi.org/10.3390/jcm11133671.

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Using 2003–2018 National Ambulatory Medical Care Survey data for office-based visits and 2003–2018 National Hospital Ambulatory Medical Care Survey data for emergency department (ED) visits, we conducted cross-sectional analyses to examine cough medication (CM) use trends in the United States (US) ambulatory care settings. We included adult (≥18 years) patient visits with respiratory-infection-related or non-infection-related cough as reason-for-visit or diagnosis without malignant cancer or benign respiratory tumor diagnoses. Using multivariable logistic regressions, we examined opioid antitu

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9

Morjaria, Jaymin B., Rebecca S. Dickinson, and Alyn H. Morice. "Novel antitussive strategies." Drug Discovery Today 18, no. 7-8 (2013): 380–88. http://dx.doi.org/10.1016/j.drudis.2012.11.004.

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10

Zou, Wei, Yonggang Wang, Haibin Liu, Yulong Luo, Si Chen, and Weiwei Su. "Melitidin: A Flavanone Glycoside from Citrus grandis ‘Tomentosa’." Natural Product Communications 8, no. 4 (2013): 1934578X1300800. http://dx.doi.org/10.1177/1934578x1300800411.

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Citrus grandis ‘Tomentosa’ is a traditional Chinese medicine, used as an antitussive. In this research, melitidin, a flavanone glycoside, was isolated from this species for the first time by using chromatographic methods. The structure was confirmed through comprehensive analyses of its ultraviolet, infrared, 1H and 13C NMR, HMBC and HMQC spectroscopic and high-resolution mass spectrometric data. Meliditin showed a good antitussive effect on cough induced by citric acid in Guinea pig, suggesting that it was a contributor to the antitussive effect of C. grandis ‘Tomentosa’.

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11

Nosáľová, G., J. Mokrý, A. Ather, and M. T. H. Khan. "Antitussive Activity of the Ethanolic Extract of Paederia foetida (Rubiaceae family) in Non-Anaesthetized Cats." Acta Veterinaria Brno 76, no. 1 (2007): 27–33. http://dx.doi.org/10.2754/avb200776010027.

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The aim of the present study was to examine the antitussive activity of the ethanolic extract of Paederia foetida (P. foetida) in conscious cats by mechanical stimulation of laryngopharyngeal (LP) and tracheobronchial (TB) mucous areas of airways. The results showed that the ethanolic extract of P. foetida at the oral dose of 200 mg kg-1 b.w. had a cough-suppressive effect. It caused a significant (p < 0.05) decrease of the number of cough efforts (NE) and frequency of cough (NE.min-1) from both LP and TB areas. The intensity of a cough attack was significantly decreased only during inspiri

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12

Tamboli, Firoj A., Asha Jadhav, Rohankumar Chavan, Vishal H. Thorat, Ajit Patil, and Shital Jadhav. "Antitussive effect of granule formulation on SO gas-induced cough in experimental animals." Indian Journal of Pharmacy and Pharmacology 9, no. 1 (2022): 24–32. http://dx.doi.org/10.18231/j.ijpp.2022.005.

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All over world cough is a common symptom in respiratory disease. When cough becomes severe, opioids act as a potent drug, but they have various side effects like sedation, constipation, etc. Therefore, there is a need to have an effective antitussive formulation, which doesn’t have respiratory depressant activity. The present study was carried out to evaluate the antitussive activity of granules containing extract using a cough model induced by Sulphur dioxide gas in experimental mice. The antitussive effect of granule formulation on SO gas induced cough in experimental animals, which compared

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13

Sohn, Jang Won. "Antitussive and mucoactive drugs." Journal of the Korean Medical Association 56, no. 11 (2013): 1025. http://dx.doi.org/10.5124/jkma.2013.56.11.1025.

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14

Swamy, G. Y. S. K., K. Ravikumar, and A. K. S. Bhujanga Rao. "Dextromethorphan, an antitussive agent." Acta Crystallographica Section E Structure Reports Online 61, no. 7 (2005): o2071—o2073. http://dx.doi.org/10.1107/s1600536805017782.

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15

ARIAN, MUHAMMAD, and JONATHAN STOEVER. "PHENOBARBITAL: THE ULTIMATE ANTITUSSIVE." CHEST 164, no. 4 (2023): A1993. http://dx.doi.org/10.1016/j.chest.2023.07.1368.

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16

Manjhi, Pramod Kumar, Sunil Kumar Singh, Chakrapani Kumar, and Akhilesh Kumar Rana. "Rational use and cost variation analysis of antitussive-expectorants available in the Indian market: a pharmacoeconomic study." International Journal of Basic & Clinical Pharmacology 10, no. 12 (2021): 1342. http://dx.doi.org/10.18203/2319-2003.ijbcp20214474.

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Background: Antitussive-expectorants are among the most frequently prescribed drugs by physicians in clinical practice. Upper respiratory tract infections, such as common cold, acute pharyngitis and acute trachea-bronchitis, are the most common of all communicable diseases and significantly increase OPD burden. This study aimed to assess the rational use, cost ratio, and percentage cost variations in different brands of the commonly prescribed antitussive-expectorants available in the Indian market.Methods: The cost of antitussive-expectorant manufactured by different pharmaceutical companies

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17

Jeong, Yeong-eun, and Jong-dae Kim. "Antitussive, Expectorant, and Anti-inflammatory Effects of Mahwangyounpae-tang, a Polyherbal Formula in ICR Mice." Journal of Internal Korean Medicine 43, no. 4 (2022): 503–13. http://dx.doi.org/10.22246/jikm.2022.43.4.503.

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Objectives: The antitussive, expectorant, and anti-inflammatory effects of Mahwangyounpae-tang (MHYPT) aqueous extracts were observed in appropriate animal models of various respiratory disorders.Methods: MHYPT aqueous extracts were orally administered once a day for 11 days at dose levels of 400, 200, and 100 mg/kg. The effect of MHYPT was determined by comparing its antitussive effect with theobromine (TB), its expectorant effect with ambroxol (AM), and its anti-inflammatory effect with dexamethasone (DEXA).Results: MHYPT aqueous extracts (400 mg/kg) showed favorable antitussive effects comp

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18

Eccles, Ronald. "Placebo and Side Effects Confound Clinical Trials on New Antitussives." Lung 199, no. 4 (2021): 319–26. http://dx.doi.org/10.1007/s00408-021-00458-2.

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AbstractThis review discusses how the placebo effect related to treatment side effects may confound clinical trials on antitussives and specifically looks at the implications for trials on ATP antagonists. These new antitussives have distinctive side effects on the sensation of taste, and investigators have expressed concerns that this may unblind the clinical trials. Blinding is an essential component of trial design, but the degree of blinding in trials is rarely assessed. The assumptions of additivity and balance in clinical trials are discussed as important factors that allow assessment of

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19

Fizeșan, Ionel, Marius Emil Rusu, Carmen Georgiu, et al. "Antitussive, Antioxidant, and Anti-Inflammatory Effects of a Walnut (Juglans regia L.) Septum Extract Rich in Bioactive Compounds." Antioxidants 10, no. 1 (2021): 119. http://dx.doi.org/10.3390/antiox10010119.

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The antitussive, antioxidant, and anti-inflammatory effects of a walnut (Juglans regia L.) septum extract (WSE), rich in bioactive compounds were investigated using the citric acid aerosol-induced cough experimental model in rodents. Wistar male rats were treated orally for three days with distilled water (control), codeine (reference), and WSE in graded doses. On the third day, all rats were exposed to citric acid aerosols, the number of coughs being recorded. Each animal was sacrificed after exposure, and blood and lung tissue samples were collected for histopathological analysis and the ass

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20

ul Haq, Rizwan, Abdul Wahab, Khurshed Ayub, et al. "Antitussive Efficacy and Safety Profile of Ethyl Acetate Fraction of Terminalia chebula." ISRN Pharmacology 2013 (August 19, 2013): 1–7. http://dx.doi.org/10.1155/2013/256934.

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Antitussive effects of ethyl acetate fraction of Terminalia chebula on sulphur dioxide (SO2) gas induced cough have been examined in mice. Safety profile of Terminalia chebula was established by determining LD50 and acute neurotoxicity. The result showed that extract of Terminalia chebula dose dependently suppressed SO2 gas induced cough in mice. Terminalia chebula, after i.p. administration at dose level 500 mg/kg, offered maximum cough suppressive effects; that is, number of coughs at 60 min was 12±1.52 (mean ± SEM) as compared to codeine 10 mg/kg; i.p., dextromethorphan 10 mg/kg; i.p., and

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21

Tan, Min-Jia, Chun Yin, Chun-Ping Tang, Chang-Qiang Ke, Ge Lin, and Yang Ye. "Antitussive Indole Alkaloids fromKopsia hainanensis." Planta Medica 77, no. 09 (2010): 939–44. http://dx.doi.org/10.1055/s-0030-1250631.

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22

Gaikwad, Ms Rutuja. "A Review: Herbal Antitussive Chocolate." International Journal for Research in Applied Science and Engineering Technology 13, no. 4 (2025): 5823–28. https://doi.org/10.22214/ijraset.2025.69004.

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The goal of this study is to create and assess a new herbal antitussive chocolate that provides a tasty and practical substitute for cough and throat discomfort. Traditional medicinal herbs that are recognised for their calming and coughsuppressing qualities, including Glycyrrhiza glabra (liquorice), Adhatoda vasica (vasaka), Zingiber officinale (ginger), and Ocimum sanctum (tulsi), are used in the composition. To improve patient compliance, particularly in the elderly and paediatric populations, the herbal extracts were incorporated into a chocolate basis. The finished product's medication co

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23

Sakami, Satoshi, Masayuki Maeda, Koji Kawai, et al. "Structure−Antitussive Activity Relationships of Naltrindole Derivatives. Identification of Novel and Potent Antitussive Agents." Journal of Medicinal Chemistry 51, no. 15 (2008): 4404–11. http://dx.doi.org/10.1021/jm701440h.

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24

Shirsat, Amar, Abhijit Trailokya, and Shaijesh Wankhede. "Levodropropizine: A promising peripherally acting antitussive agent." IP Indian Journal of Immunology and Respiratory Medicine 8, no. 2 (2023): 53–61. http://dx.doi.org/10.18231/j.ijirm.2023.013.

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Cough is one of the most frequent symptom for patients to seek medical attention. Cough can be associated with many disease processes and the ultimate treatment depends on determining the etiology and diagnosis. Antitussive agents with different mechanisms of action have been developed in the past, but there are still very few medications that seem to be effective without any side effects especially related to central nervous system (CNS). Levodropropizine is an antitussive agent which acts peripherally and is a non-opioid cough medication that is in use since many years as a symptomatic thera

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25

Yang, Liu, Hai Jiang, Song Wang, et al. "Discovering the Major Antitussive, Expectorant, and Anti-Inflammatory Bioactive Constituents in Tussilago farfara L. Based on the Spectrum–Effect Relationship Combined with Chemometrics." Molecules 25, no. 3 (2020): 620. http://dx.doi.org/10.3390/molecules25030620.

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Farfarae Flos (FF) is the dried flower bud of Tussilago farfara L, which has antitussive, expectorant, and anti-inflammatory effects. However, little research on the main active composition of FF has been reported. The purpose of this study is to find the main active compounds responsible for the three pharmacological effects (i.e., antitussive, expectorant, and anti-inflammatory effects) of Farfarae Flos, based on the spectrum–effect relationship combined with chemometrics. First, this study uses the UPLC-QDA method to establish the chromatography fingerprint of Farfarae Flos, which is combin

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26

Esther Oluwatoyin Agbaje and Kennedy Chibogu Nzeh. "Preliminary investigation of the aqueous leaf extract of Chrysophyllum albidum George Don (Sapotaceae) in laboratory-induced cough." International Journal of Life Science Research Archive 1, no. 1 (2021): 006–17. http://dx.doi.org/10.53771/ijlsra.2021.1.1.0045.

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Cough is the most common symptom of respiratory diseases, however, in distressing and severe cases, opioids are effective, but their use has been challenged by side effects such as sedation, constipation; also, by some addictive liability, as well as the compromise of respiratory function. Therefore, there is a dire need for effective antitussives that will override the limitations of the opioids. Chrysophyllum albidum (Linn), family Sapotaceae, and also known as African star apple is primarily a forest tree species with its natural occurrences in diverse ecozones in Uganda, Nigeria and Niger

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27

Mutolo, Donatella, Fulvia Bongianni, Elenia Cinelli, and Tito Pantaleo. "Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit." Journal of Applied Physiology 109, no. 4 (2010): 1002–10. http://dx.doi.org/10.1152/japplphysiol.00406.2010.

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We have previously shown that the caudal nucleus tractus solitarii is a site of action of some antitussive drugs and that the caudal ventral respiratory group (cVRG) region has a crucial role in determining both the expiratory and inspiratory components of the cough motor pattern. These findings led us to suggest that the cVRG region, and possibly other neural substrates involved in cough regulation, may be sites of action of antitussive drugs. To address this issue, we investigated changes in baseline respiratory activity and cough responses to tracheobronchial mechanical stimulation followin

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28

Azad Ahmad, Azad Ahmad, Saba Shaikh Saba Shaikh, Priyanka Goswami Priyanka Goswami, and Anthony Cordeiro Anthony Cordeiro. "Formulation and Evaluation of Gummies for Cough." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1264–69. https://doi.org/10.35629/4494-100212641269.

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One of the most prevalent medical conditions impacting the general public is cough. Cough can be hard to treat, even when the cause is identified, and it can lower a patients quality of life. After seasonal change, cough and cold are the main problem that occurs mostly. People have taken a lot of artificially manufactured antitussive medication that may cause side effects. Cough can be soothed by liquids, lozenges, cough drops, vaporisers and hot showers. Cough medicine may also be helpful but it'srecommend to consult a doctor before giving it to child younger than 6 years old. Coughing is a r

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29

Guo, Tao, Jun Qing Wei, and Jian Ping Ma. "Antitussive and expectorant activities ofPotentilla anserina." Pharmaceutical Biology 54, no. 5 (2015): 807–11. http://dx.doi.org/10.3109/13880209.2015.1080734.

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30

Dicpinigaitis, P. V., A. H. Morice, S. S. Birring, et al. "Antitussive Drugs—Past, Present, and Future." Pharmacological Reviews 66, no. 2 (2014): 468–512. http://dx.doi.org/10.1124/pr.111.005116.

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31

Kamei, Junzo, Miwa Misawa та Yutaka Kasuya. "σ-Binding sites and antitussive effect". Japanese Journal of Pharmacology 67 (1995): 30. http://dx.doi.org/10.1016/s0021-5198(19)46099-x.

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32

Poggioli, Rosanna, Augusta Benelli, Rossana Arletti, Elena Cavazzuti, and Alfio Bertolini. "Antitussive effect of K+ channel openers." European Journal of Pharmacology 371, no. 1 (1999): 39–42. http://dx.doi.org/10.1016/s0014-2999(99)00148-x.

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33

Birring, Surinder, Francesco de Blasio, Peter V. Dicpinigaitis, et al. "Antitussive therapy: A role for levodropropizine." Pulmonary Pharmacology & Therapeutics 56 (June 2019): 79–85. http://dx.doi.org/10.1016/j.pupt.2019.03.003.

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34

Dalibon, Pierre. "Thérapeutique antitussive, faire le bon choix." Actualités Pharmaceutiques 55, no. 561 (2016): 23–31. http://dx.doi.org/10.1016/j.actpha.2016.10.006.

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35

Kamei, Junzo, Yuriko Iwamoto, Tsutomu Suzuki, Miwa Misawa, Hiroshi Nagase, and Yutaka Kasuya. "Antitussive effect of dihydroetorphine in mice." European Journal of Pharmacology 260, no. 2-3 (1994): 257–59. http://dx.doi.org/10.1016/0014-2999(94)90347-6.

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36

Kamei, Junzo, and Yutaka Kasuya. "Antitussive effects of Ca2+ channel antagonists." European Journal of Pharmacology 212, no. 1 (1992): 61–66. http://dx.doi.org/10.1016/0014-2999(92)90072-c.

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37

Hosoe, Hisashi, Toshihiko Raise, Kenji Ohmori, et al. "Mucolytic and Antitussive Effects of Erdosteine." Journal of Pharmacy and Pharmacology 51, no. 8 (1999): 959–66. http://dx.doi.org/10.1211/0022357991773230.

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38

Haq, Rizwan-ul, Azhar-ul-Haq Ali Shah, Arif-ullah Khan, et al. "Antitussive and toxicological evaluation ofVitex negundo." Natural Product Research 26, no. 5 (2012): 484–88. http://dx.doi.org/10.1080/14786419.2010.534472.

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39

McLeod, Robbie L., Craig C. Correll, Yanlin Jia, and John C. Anthes. "TRPV1 Antagonists as Potential Antitussive Agents." Lung 186, S1 (2007): 59–65. http://dx.doi.org/10.1007/s00408-007-9032-z.

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40

Negro, Roberto W. Dal. "Erdosteine: Antitussive and Anti-inflammatory Effects." Lung 186, S1 (2008): 70–73. http://dx.doi.org/10.1007/s00408-007-9065-3.

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41

Parvez, L., M. Vaidya, A. Sakhardande, S. Subburaj, and T. G. Rajagopalan. "Evaluation of Antitussive Agents in Man." Pulmonary Pharmacology 9, no. 5-6 (1996): 299–308. http://dx.doi.org/10.1006/pulp.1996.0039.

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42

Kiran, Kumari* Akhil Thakur Ajeet Kumar Nikhil Kumar. "Formulation and evaluation of polyherbal antitussive." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 992–97. https://doi.org/10.5281/zenodo.11221410.

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Cough remain as untreated and symptoms of multiple disease. Cough remains a serious unmet clinical problem, both as a symptom of a range of other conditions such as asthma, chronic obstructive pulmonary disease, gastro oesophageal reflux, and as a problem in its own right in patients with chronic cough of unknown origin. Cough remains a major unmet medical need and, although the centrally acting opioids have remained the antitussive drug of choice for decades, such opioids possess many unwanted side-effects. Now a days the synthetic and novel drugs are the major source of curing any type of di

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43

Sekiguchi, Yasushi, Kazuo Takahama, Yoichiro Isohama, and Takeshi Miyata. "A Chinese medicine, TJS-105, as a novel antitussive possessing a wide spectrum of antitussive activities." Japanese Journal of Pharmacology 64 (1994): 149. http://dx.doi.org/10.1016/s0021-5198(19)50240-2.

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44

Kholodova, I. N. "Features of cough therapy in children." Meditsinskiy sovet = Medical Council, no. 17 (November 1, 2021): 102–9. http://dx.doi.org/10.21518/2079-701x-2021-17-102-109.

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This article discusses the problem of cough in children as one of the symptoms of a complicated course of acute respiratory infection. The data on the peculiarities of the course of cough in children depending on the cause, the level of damage, and age are presented. Virulence of infectious agents, immune status, and the child’s constitution may influence the development of local inflammation covering the tonsils, adenoids, pharynx, larynx. The study of respiratory problems in children remains relevant due to the need to improve therapy tactics and rehabilitation after an infection. Acute uppe

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Uwaya, D. O., E. Onoyivbe, and M. Osemwegie. "ESTIMATIONS OF PHYTOCHEMICAL COMPOSITION AND NON- ENZYMATIC ANTIOXIDANT, AND ANTITUSSIVE, EXPECTORANT AND ANALGESIC PROPERTIES OF POLYHERBAL-FORMULATED TEA." Open Journal of Bioscience Research (ISSN: 2734-2069) 5, no. 2 (2024): 15–32. https://doi.org/10.52417/ojbr.v5i2.669.

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For centuries, people have utilized combined herbal teas to address a diverse range of human health conditions like cough, cold and catarrh, pneumonia, pain arthritis, cardiovascular problems. This study aims to enumerate phytochemical composition and non-enzymatic antioxidants while also assessing the antitussive, expectorant, and analgesic properties of a polyherbal-formulated tea (Zingiber officiale, Moringa olifera, Allium sativum, Curcuma longa, Citrus limon, and Syzygium aromaticum). Colimetric methods were used to evaluate the phytochemical composition and non-enzymatic antioxidants. Th

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Скепьян, Е. Н. "Basics of Rational Use and Overview of the Antitussive Medicines Available on the Market." Рецепт, no. 4 (November 11, 2021): 470–79. http://dx.doi.org/10.34883/pi.2021.24.4.005.

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Кашель - одно из наиболее частых клинических проявлений острых инфекционных заболеваний верхних и нижних дыхательных путей. В статье рассмотрены классификация, причины возникновения, подходы к диагностике и лечению кашля. Представлена классификация противокашлевых лекарственных средств. Описаны клинико-фармакологические особенности применения отдельных противокашлевых лекарственных средств и даны рекомендации по их применению в клинической практике. Cough is one of the most common clinical manifestations of acute infectious diseases of the upper and lower respiratory tract. In the article, the

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Mega Salamatul Masruroh, Zeeshan Ali, and Viola Dwicha Asda Asda. "BIOINFORMATION STUDY OF NONI (MORINDA CITRIFOLIA) AS ANTITUSSIVE AGENT AGAINST SARS-COV-2." PROBILITAS 1, no. 01 (2022): 1–7. http://dx.doi.org/10.54482/probilitas.v1i01.80.

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Sars-Cov-2 which was first identified at the end of 2019 due to Corona Virus infection is still a worldwide pandemic because there is no specific drug that can fight this virus. Several problems, such as the performance of the vaccine that functions to relieve symptoms of Sars-Cov-2 virus infection, have sparked a new view of alternative medicine through natural ingredients as an alternative treatment for this viral infection. The chemical compound Zingiber officinale has potential as an antitussive, but its specific performance is unknown. So in this study, we will predict the molecular mecha

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Goddidit Esiro Enoyoze and MacDonald Idu. "Antitussive effects of Musanga cecropioides in animal models." World Journal of Biology Pharmacy and Health Sciences 19, no. 2 (2024): 001–9. http://dx.doi.org/10.30574/wjbphs.2024.19.2.0478.

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This study investigates the antitussive effects of Musanga cecropioides, a traditional medicinal plant, using animal models. Musanga cecropioides extracts were prepared from the leaves, roots, and root sap, and their effects were evaluated on mucus expectoration and citric acid-induced cough in mice and guinea pigs, respectively. The results indicated that aqueous and methanol extracts of Musanga cecropioides leaves and roots significantly increased mucus secretion and reduced cough frequency, with the highest effectiveness observed in methanol root extract at 100 mg/kg. These findings suggest

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Banderali, G., E. Riva, A. Fiocchi, C. I. Cordaro, and M. Giovannini. "Efficacy and Tolerability of Levodropropizine and Dropropizine in Children with Non-Productive Cough." Journal of International Medical Research 23, no. 3 (1995): 175–83. http://dx.doi.org/10.1177/030006059502300304.

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The antitussive efficacy and tolerability of dropropizine and of its enantiomer levodropropizine were evaluated in children with non-productive cough; 258 were evaluable for tolerability and 254 for efficacy. Patients randomly received either 1 mg/kg dropropizine or 2 mg/kg levodropropizine orally, three times daily for 3 days. There were statistically significant decreases in the frequency of coughing spells and nocturnal awakenings after both levodropropizine and dropropizine treatments ( P < 0.001). Gastrointestinal symptoms were mild in the two groups; somnolence was twice as frequent i

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Ahn, Chul Min. "Use of Antitussive, Mucolytic Agents and Expectorants." Journal of the Korean Medical Association 48, no. 1 (2005): 77. http://dx.doi.org/10.5124/jkma.2005.48.1.77.

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