Relevant bibliographies by topics / Antiviral agents. Epidemics

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Antiviral agents. Epidemics'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Antiviral agents. Epidemics"

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Mazzon, Michela, Ana Ortega-Prieto, Douglas Imrie, et al. "Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry." Viruses 11, no. 2 (2019): 176. http://dx.doi.org/10.3390/v11020176.

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Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made available. Broad-spectrum antivirals are drugs with the potential to inhibit infection by viruses from different groups or families, which may be deployed during outbreaks when specific diagnostics, vaccines or directly acting antivirals are not available. While pathogen-directed approaches are generally effective against a few closely related virus
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Vinod, Nikhra. "The Trans-zoonotic Virome interface: Measures to balance, control and treat epidemics." Annals of Biomedical Science and Engineering 4, no. 1 (2020): 020–27. http://dx.doi.org/10.29328/journal.abse.1001009.

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The global virome: The viruses have a global distribution, phylogenetic diversity and host specificity. They are obligate intracellular parasites with single- or double-stranded DNA or RNA genomes, and afflict bacteria, plants, animals and human population. The viral infection begins when surface proteins bind to receptor proteins on the host cell surface, followed by internalisation, replication and lysis. Further, trans-species interactions of viruses with bacteria, small eukaryotes and host are associated with various zoonotic viral diseases and disease progression. Virome interface and tra
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Sun, Jing, Xiao-Yi Hu, and Xiao-Fang Yu. "Current Understanding of Human Enterovirus D68." Viruses 11, no. 6 (2019): 490. http://dx.doi.org/10.3390/v11060490.

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Human enterovirus D68 (EV-D68), a member of the species Enterovirus D of the Picornaviridae family, was first isolated in 1962 in the United States. EV-D68 infection was only infrequently reported until an outbreak occurred in 2014 in the US; since then, it has continued to increase worldwide. EV-D68 infection leads to severe respiratory illness and has recently been reported to be linked to the development of the neurogenic disease known as acute flaccid myelitis (AFM), mostly in children, seriously endangering public health. Hitherto, treatment options for EV-D68 infections were limited to s
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Zhou, Bin, Yi-Mo Deng, John R. Barnes, et al. "Multiplex Reverse Transcription-PCR for Simultaneous Surveillance of Influenza A and B Viruses." Journal of Clinical Microbiology 55, no. 12 (2017): 3492–501. http://dx.doi.org/10.1128/jcm.00957-17.

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ABSTRACTInfluenza A and B viruses are the causative agents of annual influenza epidemics that can be severe, and influenza A viruses intermittently cause pandemics. Sequence information from influenza virus genomes is instrumental in determining mechanisms underpinning antigenic evolution and antiviral resistance. However, due to sequence diversity and the dynamics of influenza virus evolution, rapid and high-throughput sequencing of influenza viruses remains a challenge. We developed a single-reaction influenza A/B virus (FluA/B) multiplex reverse transcription-PCR (RT-PCR) method that amplif
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Tian, Yun, Jordan Jennings, Yuanying Gong, and Yongming Sang. "Viral Infections and Interferons in the Development of Obesity." Biomolecules 9, no. 11 (2019): 726. http://dx.doi.org/10.3390/biom9110726.

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Obesity is now a prevalent disease worldwide and has a multi-factorial etiology. Several viruses or virus-like agents including members of adenoviridae, herpesviridae, slow virus (prion), and hepatitides, have been associated with obesity; meanwhile obese patients are shown to be more susceptible to viral infections such as during influenza and dengue epidemics. We examined the co-factorial role of viral infections, particularly of the persistent cases, in synergy with high-fat diet in induction of obesity. Antiviral interferons (IFNs), as key immune regulators against viral infections and in
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Zarubaev, V. V., S. V. Vasilieva, Y. L. Esaulkova, et al. "PROTECTIVE ACTIVITY OF NOVEL BENZIMIDAZOLE DERIVATIVES AT EXPERIMENTAL INFLUENZA INFECTION." Russian Journal of Infection and Immunity 8, no. 2 (2018): 195–200. http://dx.doi.org/10.15789/2220-7619-2018-2-195-200.

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Influenza is an acute respiratory viral infection, which represents an important health problem. Every year, influenza causes epidemics and pandemics, leading to increase in morbidity and mortality in all regions of the globe. Due to the segmental organization of the genome and low accuracy of its replication, the influenza virus is capable of escaping the host’s immune response (antigenic drift), as well as the selection of drug-resistant variants. This calls for constant monitoring of the sensitivity of viral isolates to antiviral drugs and the development of new etiotropic antiviral agents
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Odnovorov, A. I., T. V. Grebennikova, and T. V. Pleteneva. "Specific Influenza Therapy: Current State and Prospects (Review)." Drug development & registration 9, no. 1 (2020): 83–91. http://dx.doi.org/10.33380/2305-2066-2020-9-1-83-91.

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Introduction. Respiratory infections are among the leaders in morbidity and mortality worldwide. The most severe cases of the disease are most often caused by the flu virus. Currently, there are many ways of specific prevention and treatment of influenza infection, but their effectiveness is far from ideal. This is due to the high variability of the influenza virus and the subsequent occurrence of resistance to the drugs used. In this regard, the improvement and development of antiviral drugs is an urgent task.Text. Influenza virus is an RNA-containing virus that causes massive epidemics and p
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Chen, Xiaoqing, Chunyang Wang, Lanfang Xu, et al. "A Laboratory Evaluation of Medicinal Herbs Used in China for the Treatment of Hand, Foot, and Mouth Disease." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/504563.

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Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the causative agents of hand, foot, and mouth disease (HFMD). During recent epidemics of HFMD in China, medicinal herbals and preparations containing herbal extracts have demonstrated therapeutic efficacy with relative safety profiles. There have been no microbiological studies to validate their usefulness for HFMD. We selected 12 commonly used herbs for HFMD from government recommended guidelines as well as published reports and tested for their antiviral activity and anti-inflammatory activity. A water extract ofHouttuynia cordataThunb
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Seyfoori, Amir, Mahdieh Shokrollahi Barough, Pooneh Mokarram, et al. "Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID)." International Journal of Molecular Sciences 22, no. 13 (2021): 6937. http://dx.doi.org/10.3390/ijms22136937.

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Viral-associated respiratory infectious diseases are one of the most prominent subsets of respiratory failures, known as viral respiratory infections (VRI). VRIs are proceeded by an infection caused by viruses infecting the respiratory system. For the past 100 years, viral associated respiratory epidemics have been the most common cause of infectious disease worldwide. Due to several drawbacks of the current anti-viral treatments, such as drug resistance generation and non-targeting of viral proteins, the development of novel nanotherapeutic or nano-vaccine strategies can be considered essenti
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Riblett, Amber M., Vincent A. Blomen, Lucas T. Jae, et al. "A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection." Journal of Virology 90, no. 3 (2015): 1414–23. http://dx.doi.org/10.1128/jvi.02055-15.

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ABSTRACTRift Valley fever virus (RVFV) causes recurrent insect-borne epizootics throughout the African continent, and infection of humans can lead to a lethal hemorrhagic fever syndrome. Deep mutagenesis of haploid human cells was used to identify host factors required for RVFV infection. This screen identified a suite of enzymes involved in glycosaminoglycan (GAG) biogenesis and transport, including several components of thecis-oligomeric Golgi (COG) complex, one of the central components of Golgi complex trafficking. In addition, disruption ofPTAR1led to RVFV resistance as well as reduced he
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Dissertations / Theses on the topic "Antiviral agents. Epidemics"

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Mak, Ka-ki Peter. "The potential trade-offs between treatment and prophylaxis with antivirals in households during a pandemic." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38479631.

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Mak, Ka-ki Peter, and 麥家麒. "The potential trade-offs between treatment and prophylaxis with antivirals in households during a pandemic." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39724517.

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Ng, Sophia, and 吳鈺陪. "The role of antivirals and vaccines in the control of influenza epidemics and pandemics." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49617849.

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Influenza vaccination is the best preventive measure against influenza virus infection, and antivirals including oseltamivir are effective treatments. From a public health point of view, it is important to evaluate whether vaccination and antiviral treatment reduces transmission of the virus. I analyzed data from a community-based study of influenza virus transmission in households, and identified effectiveness of antiviral treatment in reducing duration of illness and some evidence that treatment reduced transmission to household contacts. I also analyzed data from a community-based placebo-
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Leung, Yue-hin Ryan, and 梁宇軒. "Effectiveness of antiviral prophylaxis as a containment measure duringan influenza epidemic." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48424079.

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Influenza epidemics have always been a constant public health threat to human populations. Recent societal developments and demographics changes have put us at increased risk of a widespread and potentially deadly influenza epidemic. Antiviral prophylaxis may provide an important epidemic intervention measure especially against influenza epidemic caused by novel influenza viruses where there will be no effective epidemic-specific vaccines available at the initial phase of the epidemic. Antiviral prophylaxis is listed as a fundamental component of the Hong Kong Preparedness Plan for Influenza
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Johansson, Susanne. "Design and Synthesis of Sialic Acid Conjugates as Inhibitors of EKC-causing Adenoviruses." Doctoral thesis, Umeå universitet, Kemi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1641.

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The combat against viral diseases has been, and still is, a major challenge in the field of drug development. Viruses are intracellular parasites that use the host cell ma-chinery for their replication and release. Therefore it is difficult to target and destroy the viral particle without disturbing the essential functions of the host cell. This thesis describes studies towards antiviral agents targeting adenovirus type 37 (Ad37), which causes the severe ocular infection epidemic keratoconjunctivitis (EKC). Cell surface oligosaccharides serve as cellular receptors for many pathogens, including
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Olanrewaju, Folawiyo S., Ayotola Falodun, Muhammed Jawla, Patricia Vanhook, and Stacey McKenzie. "Hepatitis C Virus Screening in Federally Qualified Health Centers in Rural Appalachia." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/90.

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The prevalence of Hepatitis C Virus (HCV) in the US is estimated at 3.5 million with 18,153 deaths in 2016. It is the most common bloodborne infection, with a higher age-adjusted mortality rate than Hepatitis B Virus or Human Immunodeficiency Virus. Without treatment, nearly 1.1 million people will die from HCV by 2060. About 41,200 new cases of HCV were reported in 41 states in the US in 2016. The reported cases of acute HCV in 2016 is 2.3 per 100,000 in Tennessee, which is more than twice the national goal set by Healthy People 2020. This is a descriptive study to ascertain the HCV prevalenc
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Books on the topic "Antiviral agents. Epidemics"

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Institute of Medicine (U.S.). Board on Population Health and Public Health Practice., ed. Antivirals for pandemic influenza: Guidance on developing a distribution and dispensing program. National Academies Press, 2008.

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2

United States. Government Accountability Office. Influenza pandemic and steps to counter it. Nova Science Publishers, 2008.

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Public Engagement on Facilitating Access to Antiviral Medications and Information in an Influenza Pandemic: Workshop Series Summary. National Academies Press, 2012.

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Torrence, Paul F. Combating the Threat of Pandemic Influenza: Drug Discovery Approaches. Wiley & Sons, Incorporated, John, 2007.

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F, Torrence Paul, ed. Combating the threat of pandemic influenza: Drug discovery approaches. John Wiley & Sons, 2008.

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Herbal antivirals: Natural remedies for emerging resistant and epidemic viral infections. 2013.

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7

Alexander, D. J., N. Phin, and M. Zuckerman. Influenza. Edited by I. H. Brown. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0037.

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Influenza is a highly infectious, acute illness which has affected humans and animals since ancient times. Influenza viruses form the Orthomyxoviridae family and are grouped into types A, B, and C on the basis of the antigenic nature of the internal nucleocapsid or the matrix protein. Infl uenza A viruses infect a large variety of animal species, including humans, pigs, horses, sea mammals, and birds, occasionally producing devastating pandemics in humans, such as in 1918 when it has been estimated that between 50–100 million deaths occurred worldwide.There are two important viral surface glyc
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Book chapters on the topic "Antiviral agents. Epidemics"

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El Khiat, Abdelaati, Youssef Ait Hamdan, Lahcen Tamegart, et al. "Therapeutic Management of COVID-19 Patients." In Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-7998-8225-1.ch013.

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCov-2) or COVID-19 is a pandemic that appeared in December 2019 in China and which is an RNA virus. It gave rise to a major health crisis at the start of 2020, with numerous hospitalizations. It was quickly important to understand the pathophysiology of this viral attack on the human body in order to be able to develop treatment. However, there is no vaccine or effective therapeutic agent against SARS-CoV-2. Most of the therapeutic strategies used to deal with this virus come from the work of previous epidemics of SARS, and other influenza viruses, such as antiviral therapies (chloroquine, hydroxychloroquine), adjuvant therapies by combining antivirals with drugs. Antibiotics or immunostimulants (vitamins C, Dm and Zinc, etc,) and several other therapies to be used depending on the region.
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Journal articles
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