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Dissertations / Theses on the topic 'APEX1'

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Published: 4 June 2021
Last updated: 1 February 2022

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1

Kuasne, Hellen. "Investigação dos genes APEX1, XRCC1, PSA e AR como candidatos a marcadores moleculares para o câncer de próstata." UEL, IAPAR, EMBRAPA. Centro de Ciências Biológicas. Programa de Pós-Graduação em Genética e Biologia Molecular, 2009. http://www.bibliotecadigital.uel.br/document/?code=vtls000157963.

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O câncer de próstata é o segundo tipo de câncer mais incidente no Brasil. Dentre os genes de interesse relacionados com esta neoplasia, destacam-se os participantes da via dos andrógenos, como o Receptor de Andrógeno (AR), o Antígeno Específico da Próstata (PSA) e os da via de reparo a danos no DNA (APEX1 e XRCC1). Polimorfismos nesses genes são freqüentes na população, podendo levar a alterações das atividades gênicas e contribuir para o risco de desenvolvimento e progressão do tumor. O objetivo deste trabalho foi analisar as freqüências dos genótipos prevalentes, heterozigotos e raros dos ge
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Ferreira, Stef?nia Jer?nimo. "Avalia??o de polimorfismos funcionais nos genes de reparo XRCC1, APEX1, XPD e XPF em carcinomas de c?lulas escamosas orais." Universidade Federal do Rio Grande do Norte, 2015. http://repositorio.ufrn.br/handle/123456789/19914.

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Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-02-29T22:55:50Z No. of bitstreams: 1 StefaniaJeronimoFerreira_TESE.pdf: 1963411 bytes, checksum: 83b197f2ea9b0bdbd5ac4b4732412733 (MD5)<br>Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-03-02T19:57:46Z (GMT) No. of bitstreams: 1 StefaniaJeronimoFerreira_TESE.pdf: 1963411 bytes, checksum: 83b197f2ea9b0bdbd5ac4b4732412733 (MD5)<br>Made available in DSpace on 2016-03-02T19:57:46Z (GMT). No. of bitstreams: 1 StefaniaJeronimoFerreira_TESE.pdf: 1963411 bytes, checksum: 83b197f2ea9b0b
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Fontes, Fabr?cia Lima. "Marcadores gen?ticos associados com a resposta inflamat?ria na meningite bacteriana." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13394.

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Made available in DSpace on 2014-12-17T14:14:00Z (GMT). No. of bitstreams: 1 FabriciaLF_DISSERT.pdf: 3549779 bytes, checksum: 2364a7c4e80831b956545a9a31de3525 (MD5) Previous issue date: 2012-11-19<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>A meningite bacteriana (MB) ? uma doen?a infecto-contagiosa que apresenta altas taxas de mortalidade e morbidade, constituindo-se assim um grave problema de sa?de p?blica. ? caracterizada por uma intensa inflama??o granuloc?tica que leva a inj?ria neuronal e consequentemente surgimento de sequelas neurol?gicas. A resposta inflamat?ri
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Bernecky, Robert. "APEX, the APL parallel executor." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq28764.pdf.

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Han, Yisu Ph D. Massachusetts Institute of Technology. "Directed evolution of split APEX peroxidase." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120907.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>APEX is an engineered peroxidase that catalyzes the oxidation of a wide range of substrates, facilitating its use in a variety of applications, from subcellular staining for electron microscopy to proximity biotinylation for spatially restricted proteomics and transcriptomics. While this strategy has provided access to many cellular regions and organelles, there are still many compartments and structures that cannot be accesse
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Zuniga, David. "Flood dynamics, hazard and risks in an active alluvial fan system threatening Ciudad Juàrez Chihuahua Mexico." Thesis, Brunel University, 2012. http://bura.brunel.ac.uk/handle/2438/13049.

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The aim of this research is to assess hazards and risks associated with flooding in the city of Juárez, northern México, where there is a flood threat from active alluvial fans from mountains to the southwest and from the Rio Grande (Bravo River) to the northwest forming the northeast border of the city. Aims of this Ph.D. were addressed processing a digital elevation model (DEM) of the study area in a GIS platform to define the several alluvial fans, and thus to examine their history and palaeohydrology. Three OSL dates in the youngest parts of the fans show ages ranging from 74 - 31 ka. Howe
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Rounds, Richard Grafton. "Metaphoric reconstruction : an addition to the APEX museum." Thesis, Georgia Institute of Technology, 1995. http://hdl.handle.net/1853/21700.

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de, Graaf Niels. "Simulation of Attitude and Orbit Control for APEX CubeSat." Thesis, Luleå tekniska universitet, Rymdteknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-80736.

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CubeSats are becoming a game changer in the space industry. Appearing first for univer-sity mission, its popularity is increasing for commercial use and for deep space missionssuch as the on HERA mission that will orbit in 2026 around an asteroid as part of aplanetary defence mission. Standardisation and industrial collaboration is key to a fastdevelopment, assuring the product quality and lower development expenditures.In this study the focus is set elaborating a low cost demonstrator platform to be usedfor developing and testing onboard software on physical hardware: a Hardware-Softwaretesti
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Tiraboschi, Lisa A. "A survey of characteristics and attitudes of offices currently and previously participating in the APEX program." Thesis, Boston University, 1992. https://hdl.handle.net/2144/37821.

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Thesis (M.Sc.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1992 (Dental Public Health).<br>Includes bibliographical references: (leaves 37-39).<br>Changes in the external environment and the dental needs of the public have placed greater demands on dental schools to graduate dentists better prepared to enter dental practice. New disease patterns, an aging population, and technological advancements, as well as, rising tuition and a decline in the applicant pool, are factors which are forcing dental educators to re-evaluate the curriculum and create new methods in which de
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Kennedy, James 1983. "The APEX-SZ experiment : observations of the Sunyaev Zel'dovich effect." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116109.

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The Sunyaev Zel'dovich effect (SZE) is a secondary distortion of the cosmic microwave background (CMB) spectrum produced by galaxy clusters that allows for measurements of intra-cluster gas properties. Current experiments are using large arrays of multiplexed transition-edge sensor bolometers to achieve the sensitivities required for SZE cluster surveys and targeted cluster SZE observations. This thesis describes the APEX-SZ experiment, the first instrument to produce scientific results from observations with such an array. The scientific motivation for the APEX-SZ experiment is discussed, fol
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Teixeira, Marco Antonio. "Técnicas de reconfigurabilidade dos FPGAs da família APEX 20K - Altera." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-11092002-164901/.

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Os dispositivos lógicos programáveis pertencentes à família APEX 20K, são configurados no momento da inicialização do sistema com dados armazenados em dispositivos especificamente desenvolvidos para esse fim. Esta família de FPGAs possui uma interface otimizada, permitindo também que microprocessadores os configure de maneira serial ou paralela, síncrona ou assíncronamente. Depois de configurados, estes FPGAs podem ser reconfigurados em tempo real com novos dados de configuração. A reconfiguração em tempo real conduz a inovadoras aplicações de computação reconfigurável. Os dispositivos de con
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Melo, Julliane Tamara Ara?jo de. "An?lise da express?o de APE1 ap?s estresse oxidativo induzido em c?lulas proficientes e deficientes na via de reparo por excis?o de nucleot?deos." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13055.

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Made available in DSpace on 2014-12-17T14:10:20Z (GMT). No. of bitstreams: 1 Julliane Tamara Araujo de Melo.pdf: 3651115 bytes, checksum: d9a05a183487ffcfb8bd75edd16acd9d (MD5) Previous issue date: 2010-06-28<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>Riboflavin is a vitamin very important in aerobic organisms, as a precursor of many coenzymes involved in the electron transporter chain. However, after photosensitization of riboflavin with UV or visible light, it generates reactive oxygen species (ROS), which can oxidize the DNA. The repair of oxidative lesions on
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Klein, Matthias [Verfasser]. "WEAK LENSING MEASUREMENTS FOR THE APEX- SZ CLUSTER SURVEY / Matthias Klein." Bonn : Universitäts- und Landesbibliothek Bonn, 2014. http://d-nb.info/1077288956/34.

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14

Bhandari, Ammar B. "Improving phosphorus loss assessment with the apex model and phosphorus index." Diss., Kansas State University, 2016. http://hdl.handle.net/2097/32721.

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Doctor of Philosophy<br>Agronomy<br>Nathan O. Nelson<br>Agricultural fields contribute phosphorus (P) to water bodies, which can degrade water quality. The P index (PI) is a tool to assess the risk of P-loss from agricultural fields. However, due to limited measured data, P indices have not been rigorously evaluated. The Agricultural Policy/Environmental Extender (APEX) model could be used to generate P-loss datasets for P index evaluation and revision. The objectives of the study were to i) determine effects of APEX calibration practices on P-loss estimates from diverse management systems, ii
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Brookes, Paul Andrew. "Synthetic studies towards novel inhibitors of Ape1/Ref1 and LRH-1." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/39141.

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The work described within this thesis relates to the development and identification of novel inhibitors of two recently identified chemotherapeutic targets: (i) Apurinic/Apyrimidinic Endonuclease 1-(Ape1/Ref1). The base excision repair (BER) pathway is a vital eukaryotic process that acts to recognise, process and remove damaged DNA from the genome. A critical step in BER involves the processing of an apurinic/apyrimidinic (AP) site intermediate by Ape1/Ref1. Such AP site intermediates are generated when DNA bases undergo spontaneous damage, and as such are continuously and ubiquitously being
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Tripathi, Smita. "Fluid fractals : leadership at the apex of local authority in England." Thesis, University of Plymouth, 2013. http://hdl.handle.net/10026.1/3186.

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Purpose: This thesis aims to explore the complex phenomenon of leadership at the apex of democratically elected local authority in England. It makes sense of the social construction of leadership as perceived and enacted by senior appointed officers (hereinafter officers), elected members (hereinafter members) and key stakeholders – the voices from the apex and their understandings and interpretations. Design/methodology/approach: The thesis examines leadership literature through the paradigm of constructivism-interpretivism, making sense of transcripts of the semi-structured interviews with o
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Brand, Lucas M. DDS, Craig A. DDS Dunlap, Ray DDS MSD Scott, and Ove A. DMD MS PhD Peters. "AN IN VITRO EVALUATION OF THE WIRELE-X ELECTRONIC APEX LOCATOR." Scholarly Commons, 2021. https://scholarlycommons.pacific.edu/dugoni_etd/14.

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Aim: The aim of this study was to evaluate the accuracy of the Wirele-X (Forum Tec, Ashkelon, Israel), a new Bluetooth-enabled electronic apex locator (EAL). The accuracy of the Wirele-X and the Root ZX II (J. Morita, Tokyo, Japan) was compared in vitro using an alginate model. Materials/Methods: Thirty-one extracted single-rooted human teeth with mature apices were decoronated at the CEJ. Under 10X magnification, actual canal lengths (ACL) were determined. The teeth were embedded in alginate and electronic canal length measurements were obtained using the Root ZX II and Wirele-X EALs. Each
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Böhm, Michael. "Návrh radiálních těsnicích lišt pro Wankelův motor." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400484.

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The master’s thesis deals with analysis of sealing elements of Wankel engines and their design. The necessary steps for creation of the model of dynamics of apex seal are provided, whereby the resulting force loads are then obtained. Furthermore, the design of the apex seal spring, the choice of the material and the production jigs for the production of the spring itself are presented. The finished components are tested in the engine testing laboratory and the results evaluated.
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Krishnan, Vaidyanathan. "The nature of Turbulence in a Narrow Apex Angle Isosceles Triangular Duct." Doctoral diss., University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3811.

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An experimental investigation was performed to ascertain the nature of turbulence in a narrow apex angle isosceles triangular duct. The study involved the design and construction of a low noise, low turbulence wind tunnel that had an isosceles triangular test section with an apex angle of 11.5[degrees]. Experiments involved the measurement of velocity fluctuations using hot wire anemometry and wall pressure fluctuations using a condenser microphone. Measurement of the velocity fluctuations reconfirms the coexistence of laminar and turbulent regions at a given cross section for a range of Reyno
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Rambaud-Lavigne, Léa. "The genetics and mechanics of stem cells at the Arabidopsis shoot apex." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEN065/document.

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Les organes aériens des plantes sont générés par le méristème apical caulinaire (MAC), dont la mise en place et le maintien ont été largement étudiés. Alors qu’un vaste réseau de gènes assure une régulation robuste de la population de cellules souches, deux gènes se distinguent ; CLAVATA3 (CLV3) et WUSCHEL (WUS). CLV3 s’exprime dans les cellules souches et code pour un peptide signal dont la liaison à des récepteurs transmembranaires mène à la sous-régulation de WUS. Ce dernier code pour un facteur de transcription dans le centre organisateur sous-jacent. En retour, WUS active directement l’ex
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Coutinho, Leonam Gomes. "Estudo do papel da prote?na multifuncional APE1/Ref-1 sobre a resposta inflamat?ria na meningite bacteriana." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12649.

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Made available in DSpace on 2014-12-17T14:05:22Z (GMT). No. of bitstreams: 1 LeonamGC_TESE.pdf: 2406262 bytes, checksum: 604659dd8ff62335f952679dda971b6e (MD5) Previous issue date: 2013-03-19<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>Despite advances in antibiotic therapy, bacterial meningitis (BM) remains with high mortality and morbidity rates in worldwide. One important mechanism associated to sequels during disease is the intense inflammatory response which promotes an oxidative burst and release of reactive oxygen species, consequently leading to cell death.
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Mohammed, Mohammed Zubair Khuder. "Pre-clinical development of human apurinic/apyrimidinic endonuclease (APE1) inhibitors for cancer therapy." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/13980/.

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Modulation of DNA base excision repair (BER) has the potential to enhance response to chemotherapy and improve outcomes in tumours such as melanoma, glioma and pancreatic cancer. APE1, a critical protein in BER that processes potentially cytotoxic abasic sites (AP sites), is a promising new target in cancer. In the current study, my aim was to develop small molecule inhibitors of APE1 for cancer therapy. An industry-standard high throughput virtual screening strategy was adopted. The SYBYL8.0 (Tripos, St Louis, MO, USA) molecular modelling software suite was used to build inhibitor templates.
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Nyqvist, Marina J. "Behavioural causes and consequences of sexual size dimorphism in an apex predator species." Thesis, Bournemouth University, 2012. http://eprints.bournemouth.ac.uk/20986/.

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Individual differences within populations in a range of phenotypic traits are hypothesised to have important ecological and evolutionary implications. Variation in individual growth rates that result in corresponding variations in body sizes, including size dimorphism, is a particularly widespread feature of many animal populations. The increasing characterisation of consistent individual behavioural variations, unrelated to age or sex, is equally considered to have important fitness consequences. Our understanding of behavioural causes of size dimorphism remains weak, and few studies have inv
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Rehman, Hafiz. "Control of leading edge vortices using apex flap over non-slender delta wing." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121426.

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This thesis presents the experimental investigation of vortex flow structure over non-slender delta wing with leading edge sweep angle, Λ=45°. A comprehensive investigation has been conducted in a wind tunnel at Reynolds numbers ranging between 247,000 and 445,000. Seven-hole pressure probe measurements for flow characteristics such as normalized axial vorticity, normalized axial velocity, vortex trajectory and pressure variations are presented at various chordwise stations, angles of incidences and Reynolds number. The focus was on critical vortex flow characteristics and their dependency on
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Prosak, Trang P. "Forward and Inward Movement of the Ciliary Muscle Apex with Accommodation in Adults." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397425606.

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Hicks, Stephanie. "Identification and Characterization of Essential Residues at the Apex of the RSV FusionProtein." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1525295711785612.

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Nagai, Yuya. "T memory stem cells are the hierarchical apex of adult T-cell leukemia." Kyoto University, 2015. http://hdl.handle.net/2433/202670.

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Navarrete, Felipe [Verfasser]. "The APEX submillimeter imaging survey of distant galaxies in the COSMOS field / Felipe Navarrete." Bonn : Universitäts- und Landesbibliothek Bonn, 2015. http://d-nb.info/1080561218/34.

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Kagenishi, Tomoko [Verfasser]. "Extracellular ATP Signaling is Linked to Endocytic Vesicle Recycling in Root Apex / Tomoko Kagenishi." Bonn : Universitäts- und Landesbibliothek Bonn, 2016. http://d-nb.info/1133543170/34.

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Dempsey, James F. "The finite element analysis of apex thin and thick walled hexagonal drive tool sockets." Ohio : Ohio University, 1992. http://www.ohiolink.edu/etd/view.cgi?ohiou1172248289.

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Nagarajan, Aarti [Verfasser]. "Mass calibration of the Sunyaev-Zel'dovich effect using APEX-SZ galaxy clusters / Aarti Nagarajan." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1177881705/34.

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Batebi, Hossein [Verfasser]. "A Mechanistic Study Of The Enzymatic Excision Mechanism In AP Endonuclease (APE1) / Hossein Batebi." Berlin : Freie Universität Berlin, 2019. http://d-nb.info/119437266X/34.

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DORNELAS, BETTYSA FERREIRA. "IMPACTS OF EXPORT PROMOTION PROGRAMS: THE CASE OF THE PEIEX PROGRAM BY APEX-BRASIL." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2016. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=31324@1.

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Os benefícios econômicos e sociais da exportação – para as próprias empresas e os países – têm sido amplamente abordados na literatura. Contudo, apesar da redução nas barreiras à exportação e do consequente aumento do fluxo internacional de comércio, muitas pequenas e médias empresas (PMEs) não conseguem vender seus produtos no exterior, muitas vezes por falta de recursos ou de conhecimentos necessários para realizar com sucesso as atividades de exportação. Nesse contexto, os programas oficiais de promoção à exportação visam a auxiliar as PMEs em seus esforços de competir no exterior. Assim, o
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Sossou-Becker, Marguerite. "Etude du rôle de l' interaction entre XRCC1 et APE1 dans la stabilité génétique." Paris 6, 2005. http://www.theses.fr/2005PA066359.

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Krosner, David Gordon. "The Relationship Between the APEX Program for Instruction and High School Student Academic Success." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2738.

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An alternative high school campus in the State of Georgia introduced a new program to support academic growth and engagement among at-risk students. This program, the APEX program, merges technology with content to provide students with self-paced learning facilitated by teachers with the objective of improving test scores, course completion, and graduation. The purpose of this goals-based evaluation was to examine the relationship between APEX program usage and the academic success measures of EOCT scores, course credit accrual, and graduation; it was grounded in the behavior objectives appro
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Brofsky, Steven Andrew. "An In Vitro Evaluation of the Elements Apex Locator Using the Endo Q System." VCU Scholars Compass, 2004. http://scholarscompass.vcu.edu/etd/1033.

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The objective of this study was two-fold: 1) to determine the accuracy of the Elements Apex Locator and 2) to compare the accuracy of the alginate and Endo Q models as in-vitro apex locator testing devices. Twenty teeth were decoronated at the CEJ and triplicate measurements were made using the Elements Apex Locator. All measurements were made to the apex reading of the apex locator. True length was established by visualizing the file tip at the apex with a dental operating microscope. Measurements were then taken with the teeth mounted in an alginate model and then in the Endo Q model. T
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Leite, Luciana Cristina. "Specialty foods : o processo de internacionalização das organizações e instituições dos projetos setoriais da Apex- Brasil /." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/154213.

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Melo, Julliane Tamara Ara?jo de. "Papel da prote?na de reparo XPC na regula??o das prote?nas de reparo APE1, OGG1 e PARP-1 em c?lulas humanas e de camundongos." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12573.

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Made available in DSpace on 2014-12-17T14:03:36Z (GMT). No. of bitstreams: 1 JullianeTAM_TESE_Parcial.pdf: 7138229 bytes, checksum: a06700fccf67cc2db086f62bf86db506 (MD5) Previous issue date: 2014-02-26<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>studies using UV as a source of DNA damage. However, even though unrepaired UV-induced DNA damages are related to mutagenesis, cell death and tumorigenesis, they do not explain phenotypes such as neurodegeneration and internal tumors observed in patients with syndromes like Xeroderma Pigmentosum (XP) and Cockayne Syndro
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Lothode, Maïwenn. "Déconvolution spectrale pour la caractérisation de minéraux industriels : du laboratoire à l’imagerie aéroportée." Thesis, Nantes, 2016. http://www.theses.fr/2016NANT4022/document.

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Les activités industrielles de traitement des minerais sont à l’origine d’importantes quantités de rejets minéraux dans l’environnement. Ceux-ci ont un impact direct sur l’environnement et la santé. La caractérisation de ces rejets constitue donc un enjeu majeur en termes de suivi de la qualité des sols et des eaux. La télédétection hyperspectrale fait partie des outils qui peuvent contribuer à l’identification, à la localisation et à la cartographie à distance des minéraux marqueurs des contaminants. Ce travail a porté sur l’étude de deux sites industriels, à Thann (Haut-Rhin, France) et à Ga
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Joniot, Sabine. "Role des variations d'un profil proteique dans l'etiologie des lesions periapicales." Toulouse 3, 1989. http://www.theses.fr/1989TOU35003.

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Finkler, Timothy. "The Effect of Insulating K-Type Files on Accuracy and Reliability as Used in Two Electronic Apex Locators." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/2549.

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The purpose of this in-vitro study is to compare the accuracy and reliability of a 3rd and 4th generation electronic apex locator (EAL) in locating the apical foramen when using insulated and non-insulated K files. Forty extracted human adult single-rooted teeth were coronally sectioned and placed in agar. EAL determined tooth length measurements were compared to actual tooth measurements. Comparisons to the standard measures used correlation and paired t-test. Preliminary comparisons of the groups used ANOVA to compare the means and the Brown-Forsythe test to compare variance. In the final an
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42

Battey, Nicholas Hugh. "Growth and development at the shoot apex of Impatiens balsamina L. during flowering and reversion." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/10751.

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43

Sabelli, Paolo Antonio. "Molecular cloning of differentially expressed and cell cycle-related cDNAs in the maize root apex." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385822.

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44

Kohl, Vanessa [Verfasser], and Alice [Akademischer Betreuer] Fabarius. "Synthetische Letalität von PARP- und APE1-Inhibitoren bei hämatologischen Neoplasien / Vanessa Kohl ; Betreuer: Alice Fabarius." Heidelberg : Universitätsbibliothek Heidelberg, 2021. http://d-nb.info/1237750598/34.

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45

Stock-Schröer, Annika Marie [Verfasser], Nikolaj [Gutachter] Klöcker, and Johannes [Gutachter] Stegbauer. "Entwicklung von APEX2-Fusionskonstrukten zur Analyse der subzellulären Proteinprozessierung / Annika Marie Stock-Schröer ; Gutachter: Nikolaj Klöcker, Johannes Stegbauer." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2021. http://d-nb.info/1240475497/34.

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46

Matar, Dalila Aïcha. "Evolution pariétale dans le continuum apex-procambium-cambium et au cours de la différenciation du phloème." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376078159.

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47

Montaldi, Ana Paula de Lima. "Influência do Gene APE1/REF-1 nas Respostas Celulares das Linhagens de Glioblastoma ao Quimioterápico Temozolomida." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/17/17135/tde-24102013-103232/.

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A proteína APE1 (do inglêsApurinic/Apyrimidinicendonuclease 1/ Redox Factor-1 - APE1/REF-1) é uma enzima multifuncional, cuja expressão encontra-se frequentemente aumentada em gliomas. Além de apresentar atividade no reparo por excisão de base (BER), o gene APE1 também atua como fator de redução, mantendo fatores de transcrição (FTs) em um estado reduzido ativo. A via BER de reparo do DNA tem sido apontada como um possível fator de resistência a terapias baseadas no uso de agentes alquilantes, tais como temozolomida (TMZ). No presente trabalho, utilizou-se a estratégia de inibição da transcriç
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48

Le, Roux Elizabeth. "The role of apex predators in ecosystem function: fear triggered cascades regulated by differential prey vulnerability." Thesis, Nelson Mandela Metropolitan University, 2016. http://hdl.handle.net/10948/14774.

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Trophic cascades involving large terrestrial mammals are very seldom empirically demonstrated. The high species diversity often associated with terrestrial systems is thought to modulate the strength of trophic cascades. In speciose systems, species often vary in vulnerability to consumption, hence some species are less responsive to top-down pressure. African large mammalian herbivores are highly diverse and vary greatly in body size, a characteristic linked to vulnerability to predation. Moreover, Africa is one of the last places to still support megaherbivores, species that have grown large
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49

Oliveira, Viviane Alves de. "Imunoexpressão das proteínas APE1, XRCC1, p53 e Ki67 em carcinoma de células escamosas de língua oral." PROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2018. https://repositorio.ufrn.br/jspui/handle/123456789/25470.

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Submitted by Automação e Estatística (sst@bczm.ufrn.br) on 2018-06-15T21:32:04Z No. of bitstreams: 1 VivianeAlvesDeOliveira_TESE.pdf: 3374047 bytes, checksum: 44d9876dbb2ee4424f40958d76b2c3ba (MD5)<br>Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2018-06-19T22:23:53Z (GMT) No. of bitstreams: 1 VivianeAlvesDeOliveira_TESE.pdf: 3374047 bytes, checksum: 44d9876dbb2ee4424f40958d76b2c3ba (MD5)<br>Made available in DSpace on 2018-06-19T22:23:53Z (GMT). No. of bitstreams: 1 VivianeAlvesDeOliveira_TESE.pdf: 3374047 bytes, checksum: 44d9876dbb2ee4424f40958d
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Zeadan, Husham. "Rapports entre les apex des dents de sagesse et le canal mandibulaire : bilan radiologique; déduction thérapeutique." Paris 7, 1985. http://www.theses.fr/1985PA07F115.

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La contiguïté topographique évidente entre la dent de sagesse inférieure et le canal dentaire inférieur peut avoir des conséquences fâcheuses, parfois inéluctables, lors de l'extraction de cette dent. Les lésions nerveuses post-opératoires sont les conséquences les plus sérieuses. La première partie de ce travail est consacrée à l'anatomie, embryologie et pathogénie de la dent de sagesse inférieure et du nerf dentaire inférieur. La deuxième partie concerne l'étude clinique. Nous avons essayé, dans cette étude, de faire un bilan radiologique complet pour montrer le rapport précis entre l'apex d
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