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Journal articles on the topic 'APGD-t'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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1

Schuerger, Andrew C., Steven Trigwell, and Carlos I. Calle. "Use of non-thermal atmospheric plasmas to reduce the viability ofBacillus subtilison spacecraft surfaces." International Journal of Astrobiology 7, no. 1 (2008): 47–57. http://dx.doi.org/10.1017/s1473550407004016.

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AbstractAtmospheric pressure glow-discharge (APGD) plasmas have been proposed for sterilizing spacecraft surfaces prior to launch. The advantages of APGD plasmas for the sterilization of spacecraft surfaces include low temperatures at treatment sites, rapid inactivation kinetics of exposed microbial cells, physical degradation and removal of microbial cells, physical removal of organic biosignature molecules, and short exposure times for the materials. However, few studies have tested APGD plasmas on spacecraft materials for their effectiveness in both sterilizing surfaces and removal of micro

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2

Coulombe, S., V. Léveillé, S. Yonson, and R. L. Leask. "Miniature atmospheric pressure glow discharge torch (APGD-t) for local biomedical applications." Pure and Applied Chemistry 78, no. 6 (2006): 1147–56. http://dx.doi.org/10.1351/pac200678061147.

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The operating parameters of a miniature atmospheric pressure glow discharge torch (APGD-t) are optimized for the production of excited atomic oxygen, and the effect of the plasma jet on endothelial cells grown in Petri dishes is studied. We first demonstrate the importance of accounting for the effect of the voltage probe used to measure the electrical parameters of the torch on its ignition and operation characteristics. When operated with a main plasma gas flow rate of 1 SLM He and a power level of ~1 W, the torch shows an optimum in the production of excited atomic oxygen for a O2 flow of ~

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3

Bastian, Februadi, Ani Suryani, and Titi Candra Sunarti. "PENINGKATAN KECERAHAN PADA PROSES SINTESIS SURFAKTAN NONIONIK ALKIL POLIGLIKOSIDA (APG) BERBASIS TAPIOKA DAN DODEKANOL." Reaktor 14, no. 2 (2012): 143. http://dx.doi.org/10.14710/reaktor.14.2.143-150.

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Alkylpolyglycosides (APG) is a nonionic surfactant that has been getting some green labels such asEcocert, EU Eco-flower and Green Seal as an environmentally friendly surfactant. Sugar is the mainraw material which is supplied the hydrophilic group, and fatty alcohol as hydrophobic group. Someundesirable compounds formed during the APG production and caused low quality. The aim of thisresearch to increase the quality and performance of APG, by controlling its process. Addition 0-10%of activated carbon and 0-0.3% of NaBH4 in APG pre-purification process; 2% (w/w) of H2O2, 35%and 500 ppm of MgO

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4

Bing, So Jin, Danbee Ha, Insun Hwang, et al. "Protective Effects on Central Nervous System by Acidic Polysaccharide of Panax ginseng in Relapse-Remitting Experimental Autoimmune Encephalomyelitis-Induced SJL/J Mice." American Journal of Chinese Medicine 44, no. 06 (2016): 1099–110. http://dx.doi.org/10.1142/s0192415x16500610.

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Bearing pathologic and clinical similarities to human multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE) is used as a murine model to test potential therapeutic agents for MS. Recently, we reported the protective effects of an acidic polysaccharide of Panax ginseng (APG) in C57BL/6 strain-dependent EAE, a model of primary progressive MS. In this study, we extend our previous findings on the therapeutic capacity of APG in relapsing-remitting EAE (rr-EAE), the animal model to closely mimic recurrent inflammatory demyelination lesions of relapsing-remitting MS. Treatments wi

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Kazi, Mohsin, Abdullah Alhajri, Sultan M. Alshehri, et al. "Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations." Pharmaceutics 12, no. 8 (2020): 749. http://dx.doi.org/10.3390/pharmaceutics12080749.

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Apigenin (APG) is a very well-known flavonoid for its anti-inflammatory and anticancer properties. The purpose of this study is to improve the solubility and bioavailability of APG using a stable bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS). APG was incorporated in an oil phase comprising coconut oil fatty acid, Imwitor 988, Transcutol P, and HCO30 to form a Bio-SNEDDS. This preparation was characterized for morphology, particle size, and transmission electron microscopy (TEM). The APG performance was investigated in terms of loading, precipitation, release and stability te

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6

Shin, Daniel Sanghoon, Eri Srivatsan, Hassan Nasser, et al. "Potential role of botanical drug APG-157 as immune adjuvant in patients with oral squamous cell carcinoma." Journal of Clinical Oncology 37, no. 15_suppl (2019): e17572-e17572. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e17572.

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e17572 Background: Natural botanical drugs, such as curcumin, resveratrol and related flavonoids, are under clinical studies. Previous pilot study of curcumin, a polyphenol, for normal and patients with oral squamous cell carcinoma (OSCC) showed significant inhibition of inflammatory cytokines in saliva. Phase I investigation was performed on APG-157 to evaluate the potential utility an as oral drug for the treatment of OSCC. Methods: A double-blind, randomized, placebo-controlled phase I clinical trial was conducted with a botanical preparation containing a combination of curcumin related pol

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7

Xie, Yan, Chengcheng FU, Lingzhi Yan, et al. "Targeting 1q21 Amplification with APG2575 and Lenalidomide to Sensitize BCL-2 Inhibition with the Decrease of MCL-1 Protein in High Risk MM Models." Blood 136, Supplement 1 (2020): 46–47. http://dx.doi.org/10.1182/blood-2020-139195.

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Background Multiple myeloma (MM) is a heterogenous plasma cell malignancy. About 30-40% of newly diagnosed and 20-60% of relapsed/refractory MM patients carry 1q21 amplification worldwide, a high-risk indicator for poor prognosis in RRMM. Different BCL-2 family anti-death proteins play important roles in MM survival and drug resistance. High expression of BCL-2 due to t (11;14) renders cell vulnerability to BCL-2 antagonist, however, patients carrying other genetic abnormality including 1q21 amplification have limited response to the newly emerged treatment choice. With MCL-1 upregulation acco

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Tréhu, Anne M., Alexander de Moor, José Mieres Madrid, et al. "Post-seismic response of the outer accretionary prism after the 2010 Maule earthquake, Chile." Geosphere 16, no. 1 (2019): 13–32. http://dx.doi.org/10.1130/ges02102.1.

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Abstract To investigate the dynamic response of the outer accretionary prism updip from the patch of greatest slip during the 2010 Mw 8.8 Maule earthquake (Chile), 10 ocean-bottom seismometers (OBSs) were deployed from May 2012 to March 2013 in a small network with an inter-instrument spacing of 7–10 km. Nine were recovered, with four recording data from intermediate-band three-component seismometers and differential pressure gauges, and five recording data from absolute pressure gauges (APGs). All instruments were also equipped with fluid flow meters designed to detect very low rates of flow

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9

Zhang, Xing, Xizhi Wen, Chen Yang, et al. "A phase I study of a novel MDM2-P53 antagonist APG-115 in Chinese patients with advanced soft tissue sarcomas." Journal of Clinical Oncology 37, no. 15_suppl (2019): 3124. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.3124.

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3124 Background: APG-115 is a novel and orally active small-molecule MDM2 inhibitor. APG-115 alone or in combination with chemotherapeutic, targeted or IO agents have shown potent antitumor activities in multiple human xenograft tumor models and human cancer patient derived xenograft (PDX) models. Methods: The patients with advanced solid tumors were enrolled in this study in China (CTR20170975). The study objectives were to assess safety, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of APG-115. The patients received APG-115 (ranging 100–200 mg) orally QOD for first 21 d

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10

ROY, DILIP KR, N. ODYUO, and LEONID V. AVERYANOV. "Tupistra ashihoi (Asparagaceae), a new species from north-eastern India." Phytotaxa 305, no. 1 (2017): 52. http://dx.doi.org/10.11646/phytotaxa.305.1.8.

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Tupistra Ker Gawler (1814: 1655) belonging to Asparagaceae subfamily Nolinoideae (APG 2009, Chase et al. 2009), includes about 26 species (Govaerts 2016). These taxa spread mainly in south and south-east of continental Asia, including Nepal, Bhutan, India, Myanmar, China, Laos, Vietnam, Thailand and Malaysia (Tanaka 2003a, 2003b, 2010a, 2010b, Averyanov et al. 2016). This genus is characterised by leaves with slender petiolar base, relatively large stigma broader than the style, stout columnar style almost as thick as the ovary and usually tuberculate, dirty green, globular berry-like fruit (T

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11

Truksa, Jaroslav, Jonathan Flanagan, Pauline Lee, and Ernest Beutler. "Characterization of IL-6 Responsive Elements in Hepcidin Promoters at the Molecular Level: Lessons from the Two Closely Related Promoter Sequences, Murine Hepc1 and Hepc2." Blood 108, no. 11 (2006): 1555. http://dx.doi.org/10.1182/blood.v108.11.1555.1555.

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Abstract Hepcidin is an antimicrobial peptide that plays an important role in regulation of iron metabolism. There is one hepcidin peptide in humans and two hepcidin peptides in mice, hepcidin 1 and hepcidin 2, the murine mature peptides sharing 68% homology at the amino-acid level. The promoter region of these two genes is highly conserved (92% homology of 500 bp promoter sequence from the start of translation). However, regulation of transcription of these two genes is different. Human hepcidin and murine hepcidin 1 mRNA levels become elevated in response to iron excess and inflammation, whi

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12

ROY, DILIP KR, ASHIHO A. MAO, and LEONID V. AVERYANOV. "Lectotypification of Peliosanthes macrophylla (Asparagaceae), and its amended morphological description." Phytotaxa 323, no. 2 (2017): 194. http://dx.doi.org/10.11646/phytotaxa.323.2.8.

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Peliosanthes Andrews (1808: 605) belongs to the subfamily Nolinoideae (Chase et al. 2009) of Asparagaceae (APG 2016). This genus contains 60–65 species distributed widely in South and Southeast Asia (Nguyen et al. 2017). Peliosanthes macrophylla Wall. in Baker (1879: 505) was described by Baker based on the collections made from “Himalaya Orientalis” in Sikkim and Mishmi. In the original description, Baker cited three collectors (J.D. Hooker & T. Thomsons, C.B. Clarke and W. Griffith). The first author could trace the collection of J.D. Hooker & T. Thomson (s.n., K000099377!, K00009937

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13

Sallman, David A., Tracey Iraca, Casey L. O'Connell, Rafael Bejar, and Sandra Kurtin. "Improving Understanding of MDS Using an Animated Patient's Guide to Benefit Patient Health Outcomes." Blood 136, Supplement 1 (2020): 16–17. http://dx.doi.org/10.1182/blood-2020-134647.

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Background: Patients with MDS continue to report gaps in knowledge, particularly where understanding of disease risk, prognosis and treatment options are concerned.1 A recent online social media survey on experiences in myelodysplastic syndromes revealed that patients/caregivers' (n=127) have a general lack of information about MDS and insufficient knowledge regarding treatment options and are unable to make fully informed decisions.2 Efforts to improve patient and caregiver understanding of MDS, including treatment options, are critical to individualized treatment planning and shared decision

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14

He, Jian, Hao Shu, Lei Zhang, et al. "Preparation of Lignite Dust Suppressant by Compound Surfactants and Effect of Inorganic Salt on Dust Suppressant." Advances in Materials Science and Engineering 2020 (October 18, 2020): 1–9. http://dx.doi.org/10.1155/2020/6278703.

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In order to improve the safety, operability, and cleanability of the dust suppressant, this paper uses the surfactant monomers selected in the previous experiment as the main material formula and adds the inorganic salt as the synergist to prepare the dust suppressant for the PMX. The wetting property of the solution was characterized by the surface tension and contact angle of the pressed coal pieces. The sedimentation experiment was used to screen the compounding system of the surfactant. Finally, the dust suppressant was used to reduce the dust of the PMX in the coal dust simulation system.

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15

Zhang, Xulin. "MDM2 inhibitors: Targeting p53-MDM2 interaction to anti-cancer." E3S Web of Conferences 308 (2021): 02015. http://dx.doi.org/10.1051/e3sconf/202130802015.

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P53 is a recognized tumor suppressor gene, which mainly depends on the activity of its transfer factor to realize the tumor suppressor effect. Mouse two-minute 2 (MDM2) is an important inhibitor of p53. When combined with MDM2, the activity of p53 will be reduced, and the anti-cancer effect will be weakened. According to the mechanism between p53 and MDM2, researchers focus on the inhibitors to inhibit their binding. Through a large number of drug screening methods and means, this article has found many new inhibitors of p53-MDM2 interaction, most of which are still in the clinical research st

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16

Xu, W., B. Westwood, CS Bartsocas, JJ Malcorra-Azpiazu, K. Indrak, and E. Beutler. "Glucose-6 phosphate dehydrogenase mutations and haplotypes in various ethnic groups." Blood 85, no. 1 (1995): 257–63. http://dx.doi.org/10.1182/blood.v85.1.257.bloodjournal851257.

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Mutations that produce glucose-6-phosphate dehydrogenase (G6PD) deficiency have been identified in samples from patients with hemolytic disease in the United States, and in G6PD-deficient samples from Greece, the Canary Islands, the Czech and Slovak Republics, South China, and in samples from the Coriell Cell Repository. Eight new mutations are described. Particularly unusual were a nonsense mutation (“G6PD Georgia”1284A), a deletion of six bases (“G6PD Stony Brook” 724– 729 del) coding for two amino acids, and a deletion of the invariant dinucleotide ApG at the 3′ acceptor splice site in the

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17

Pioli, R. N., E. N. Morandi, C. O. Gosparini, and A. L. Borghi. "First Report on Pathogenic Variability of Different Isolates of Diaporthe phaseolorum var. meridionalis on Soybean in Argentina." Plant Disease 83, no. 11 (1999): 1071. http://dx.doi.org/10.1094/pdis.1999.83.11.1071b.

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The objective of this study was to characterize the pathogenicity of several local isolates of Diaporthe phaseolorum (Cooke & Ellis) Sacc. var. meridionalis Fernández and its anamorph, Phomopsis phaseoli (Desmaz.) Sacc. meridionalis Morgan-Jones, the causal agent of southern stem canker of soybean (Glycine max (L.) Merr.), in soybean lines carrying major resistance genes. Soybean plants with typical stem canker symptoms were collected during the 1996 to 1997 and 1997 to 1998 growing seasons in the central and southern areas of Santa Fe Province, Argentina. The pathogen was isolated from th

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18

Chin, Venessa T., Adnan Nagrial, Lorraine A. Chantrill, et al. "From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e15029-e15029. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15029.

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e15029 Background: Pancreatic cancer (PC) is a highly lethal disease with few effective treatment options for metastatic disease. PC is a genetically highly heterogeneous disease that lends itself to a personalised approach to translational research (Biankin et al. Nature. 2012 Nov 15;491(7424):399-405.). Genomic sequence data from the Australian Pancreatic Genome Initiative (APGI) has identified a subset of patients with ROCK-1 amplification. ROCK-1 is a downstream target of Rho, a small GTPase, which is involved in cell adhesion and motility and has been shown to play a role in cancer cell g

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19

Koniswara, Sanjung, and Tri Suris Lestari. "GAYA KEPEMIMPINAN SITUASIONAL TERHADAP MOTIVASI KERJA KARYAWAN PADA PT GARUDA INDONESIA (PERSERO) TBK CABANG KUPANG." EKOBIS : Jurnal Ilmu Manajemen dan Akuntansi 7, no. 1 (2019): 1–15. http://dx.doi.org/10.36596/ekobis.v7i1.69.

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Based on Kompas news, it is known that several pilots who are members of the Garuda Pilot Association (APG) conducted a strike because of management problems. Employees (pilots) assume that management always makes unilateral decisions on every policy made. This study aims to determine the effect of situational leadership style on employee work motivation at PT Garuda Indonesia (Persero) Tbk Kupang Branch. The independent variable under study is the situational leadership style (X), while employee work motivation (Y) as the dependent variable is examined. Situational leadership style variables

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20

Campos, Ana Caroline De Souza, and Mário Augusto Gonçalves Jardim. "Composição florística da regeneração de um trecho de savana na Amazônia Oriental." Revista Brasileira de Geografia Física 13, no. 6 (2020): 2777. http://dx.doi.org/10.26848/rbgf.v13.6.p2777-2787.

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O objetivo da pesquisa foi conhecer a composição florística da regeneração natural de um trecho de savana amazônica no estado do Pará. O estudo foi realizado em uma savana na localidade de Itapuá, município de Vigia de Nazaré, Pará a 93 km da cidade de Belém. A coleta de dados ocorreu mensalmente no período de setembro de 2019 a fevereiro de 2020 em 80 subparcelas de 1 x 1m alocadas aleatoriamente correspondente a 480 subparcelas em um total de 480 m2. Em cada subparcela foram identificadas e quantificadas todas as espécies com altura ≤ 1 m. A identificação botânica in loco foi realizada por u

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21

Merzlikine, Alexei G., Sergey V. Voskresensky, Eugene O. Danilov, Andrei V. Fedorov, Michael A. J. Rodgers, and Douglas C. Neckers. "Observation of the two triplet state conformations of alkyl phenylglyoxylatesDedicated to Professor Dr J. W. Neckers in honor of his 101st birthday.Electronic supplementary information (ESI) available: Synthetic procedures and characterization of APGs, description of spectra processing procedures, time-resolved FTIR spectra and kinetic traces demonstrating steric and d-isotope effects, 3D structures of cyclohexyl phenylglyoxylate and t-Bu-cyclohexyl glyoxylate conformers. See http://www.rsc.org/suppdata/pp/b4/b404580g/." Photochemical & Photobiological Sciences 3, no. 9 (2004): 892. http://dx.doi.org/10.1039/b404580g.

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22

"Wave Detection of Acceleration Plethysmogram Based on a Closed Loop Feedback Mechanism." International Journal of Innovative Technology and Exploring Engineering 9, no. 7 (2020): 215–20. http://dx.doi.org/10.35940/ijitee.g5180.059720.

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Acceleration plethysmogram (APG), which corresponds to the second derivative of the photoplethysmogram (PPG) is a noninvasive method for investigating arterial wall thickness and predicting cardiovascular diseases. To perform an APG wave analysis, five inflection points of the APG waveform (a, b, c, d, and e waves) must be successfully obtained. However, an abrupt change in PPG amplitude due to various physiological conditions and patient’s movement has made it very difficult to detect the five waves of the APG waveform in real time. Therefore, to resolve this problem, two stabilization method

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23

Bomfim, Airã De Lima. "FLORA DA BAHIA: BIA KLOTZSCH E TRAGIA L. (EUPHORBIACEAE)." Anais dos Seminários de Iniciação Científica, no. 21 (November 1, 2017). http://dx.doi.org/10.13102/semic.v0i21.2377.

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Euphorbiaceae possui cerca de 300 gêneros e 6000 espécies. No Brasil, ocorrem cerca de 70 gêneros e aproximadamente 1000 espécies, representando uma das mais complexas famílias da flora brasileira (Souza & Lorenzi, 2012). No estado da Bahia ocorrem cerca de 40 gêneros e 260 espécies (Cordeiro et al., 2016). Sendo considerada como uma família morfologicamente bem delimitada pela presença de um ovário súpero, tricarpelar e trilocular com um óvulo por lóculo (APG III 2009).Bia é um pequeno gênero neotropical com cinco espécies (Webster 2007). Segundo Cordeiro et al. (2016) são registradas dua

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Chen, Peter. "Community without Flesh." M/C Journal 2, no. 3 (1999). http://dx.doi.org/10.5204/mcj.1750.

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On Wednesday 21 April the Minister for Communications, Information Technology and the Arts introduced a piece of legislation into the Australian Senate to regulate the way Australians use the Internet. This legislation is presented within Australia's existing system of content regulation, a scheme that the Minister describes is not censorship, but merely regulation (Alston 55). Underlying Senator Alston's rhetoric about the protection of children from snuff film makers, paedophiles, drug pushers and other criminals, this long anticipated bill is aimed at reducing the amount of pornographic mat

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