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Journal articles on the topic 'Application to cancer therapy'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Nikam, Rutuja, Sharma Y, and Patil D. "Nanotechnology: Applications in Cancer Therapy and Diagnosis." Nanomedicine & Nanotechnology Open Access 9, no. 3 (2024): 1–9. http://dx.doi.org/10.23880/nnoa-16000312.

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These days, Probably the most serious diseases in the entire globe is cancer in the world, and its prevalence is rapidly increasing. Uncontrolled cell development is the cause of it. Although It is always critical for higher specificity and concern about toxic waste across the system, cancer medicines have made significant progress. Recent technological breakthroughs, particularly in the area of biomaterials, have contributed to the spike in early identification, which is crucial for improving patients' prognosis and quality of life. Many of the drawbacks associated with conventional pharmaceu

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MBBS MD, Dr Asmita Jain. "Metformin in Cancer Prevention and Therapy: New Application of an Old Drug." Journal of Medical Science And clinical Research 05, no. 04 (2017): 20333–37. http://dx.doi.org/10.18535/jmscr/v5i4.97.

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Wang, Zixin. "Application of cytokines in the treatment of breast cancer." Highlights in Science, Engineering and Technology 74 (December 29, 2023): 632–38. http://dx.doi.org/10.54097/fkrca760.

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Breast cancer is one of the most common cancers in women globally. Breast cancer is still a major public health issue despite great advancements in diagnosis and treatment. In 2020, there will be about 2.3 million new cases of breast cancer, including about 600,000 deaths. In China, breast cancer is the most common cancer among women aged 15-44, and its mortality rate is on the rise. In recent years, researchers have focused on using cytokines as a potential therapy for breast cancer. Small proteins known as cytokines are essential in the immune system's response to cancer cells. This article

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Jiang, Xinmei. "The pharmacology of paclitaxel in cancer therapy." BIO Web of Conferences 166 (2025): 02002. https://doi.org/10.1051/bioconf/202516602002.

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Paclitaxel (PTX) had been identified as an anticancer ingredient from the bark of T. brevifolia by 1967. In 1971, it had officially entered the National Cancer Institute drug development program. PTX is a microtubule-stabilizing drug that has been approved for treating various kinds of cancers as a first-line or a second-line drug. As a natural anticancer drug, PTX targets in microtubules to block cell divisions, thereby leading to tumor cells death. It has a wide use of clinical applications in treating various cancer, including ovarian cancer, bladder cancer and breast cancer etc. In this re

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Misra, Ranjita, Sarbari Acharya, and Sanjeeb K. Sahoo. "Cancer nanotechnology: application of nanotechnology in cancer therapy." Drug Discovery Today 15, no. 19-20 (2010): 842–50. http://dx.doi.org/10.1016/j.drudis.2010.08.006.

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Coelho, Ethanielda De Lima, Francisco Célio Feitosa De França, Louhana Moreira Rebouças, et al. "APPLICATION OF CURCUMINOIDS-LOADED NANOEMULSION FOR CANCER THERAPY." Journal of Applied Pharmaceutical Sciences and Research 5, no. 3 (2022): 34–39. http://dx.doi.org/10.31069/japsrv5i3.04.

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INTRODUCTION: Curcuminoids and Oleic acid, reported in the literature as antioxidant and antitumor agents, were combined in nanoemulsion, using Pluronic F127 as a stabilizer. METHODS: The main objective is to investigate its cytotoxic activity against cancer cells. RESULTS AND DISCUSSION: The nanoemulsion show values of the particle size (251.4 ± 4.6 nm), zeta potential (-34.8 ± 1.0 mV), and pH (4.8) classifying it as stable and non-irritating for pharmacological applications. The main results indicate that, in the toxicity test in fish (Zebrafish), the nanoformulation proved to be

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Wang, Sumei, Shunqin Long, and Wanyin Wu. "Application of Traditional Chinese Medicines as Personalized Therapy in Human Cancers." American Journal of Chinese Medicine 46, no. 05 (2018): 953–70. http://dx.doi.org/10.1142/s0192415x18500507.

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Although lots of great achievements have been gained in the battle against cancer during the past decades, cancer is still the leading cause of death in the world including in developing countries such as China. Traditional Chinese medicine (TCM) is popular in Chinese and East Asian societies as well as some other Western countries and plays an active role in the modern healthcare system including patients with cancer, which may act as a potential effective strategy in treating human cancers. In this review, we aimed to introduce the mechanisms of TCM compound, as an option of individualized t

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Wang, Jiawei, Yan Bao, and Yandan Yao. "Application of Bionanomaterials in Tumor Immune Microenvironment Therapy." Journal of Immunology Research 2021 (February 10, 2021): 1–10. http://dx.doi.org/10.1155/2021/6663035.

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Targeted therapy for the cancer immune system has become a clinical reality with remarkable success. Immune checkpoint blockade therapy and chimeric antigen receptor T-cell (CAR-T) immunotherapy are clinically effective in a variety of cancers. However, the clinical utility of immunotherapy in cancer is limited by severe off-target toxicity, long processing time, limited efficacy, and extremely high cost. Bionanomaterials combined with these therapies address these issues by enhancing immune regulation, integrating the synergistic effects of different molecules, and, most importantly, targetin

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Setayesh-Mehr, Zahra, and Mahdiye Poorsargol. "Toxic proteins application in cancer therapy." Molecular Biology Reports 48, no. 4 (2021): 3827–40. http://dx.doi.org/10.1007/s11033-021-06363-4.

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10

Akiyode, O., D. George, J. Boateng, and G. Getti. "Application of Biosurfactants in Cancer Therapy." Annals of Oncology 26 (March 2015): ii28. http://dx.doi.org/10.1093/annonc/mdv095.4.

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11

Ko, Jeong-Hyeon, Seok-Geun Lee, Woong Yang, et al. "The Application of Embelin for Cancer Prevention and Therapy." Molecules 23, no. 3 (2018): 621. http://dx.doi.org/10.3390/molecules23030621.

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Embelin is a naturally-occurring benzoquinone compound that has been shown to possess many biological properties relevant to human cancer prevention and treatment, and increasing evidence indicates that embelin may modulate various characteristic hallmarks of tumor cells. This review summarizes the information related to the various oncogenic pathways that mediate embelin-induced cell death in multiple cancer cells. The mechanisms of the action of embelin are numerous, and most of them induce apoptotic cell death that may be intrinsic or extrinsic, and modulate the NF-κB, p53, PI3K/AKT, and ST

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12

Koohi Moftakhari Esfahani, Maedeh Koohi Moftakhari, Seyed Ebrahim Alavi, Peter J. Cabot, Nazrul Islam, and Emad L. Izake. "Application of Mesoporous Silica Nanoparticles in Cancer Therapy and Delivery of Repurposed Anthelmintics for Cancer Therapy." Pharmaceutics 14, no. 8 (2022): 1579. http://dx.doi.org/10.3390/pharmaceutics14081579.

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This review focuses on the biomedical application of mesoporous silica nanoparticles (MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and specifically on overcoming the challenges of currently available anthelmintics (e.g., low water solubility) as repurposed drugs for cancer treatment. MSNs, due to their promising features, such as tunable pore size and volume, ability to control the drug release, and ability to convert the crystalline state of drugs to an amorphous state, are appropriate carriers for drug delivery with the improved solubility of hydrophobic

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13

Ivanovic, Vesna. "Transforming growth factor-β: Biology and application to cancer therapy". Archive of Oncology 17, № 3-4 (2009): 61–64. http://dx.doi.org/10.2298/aoo0904061i.

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Transforming growth factor-? (TGF-?), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis. Consequently, TGF-? is currently explored as a prognostic candidate biomarker of tumor invasiveness and metastasis. Therefore, in clinical scenarios involving increased TGF-? activity, attempts to decrease or abrogate TGF-? signaling could be used as a therapy for advanced or metastatic disease. It follows that TGF-? signaling offers an attractive target for cancer therapy. Several anti-TGF

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Kim, Kwang Yoon. "Evidence and clinical application of intravenous nutrition therapy." Korean Institute for Functional Medicine 6, no. 2 (2023): 59–65. http://dx.doi.org/10.32581/jkifm.2023.6.2.59.

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Intravenous nutrition therapy (IVNT) of functional medicine is often used as a confused concept with amino acid fluids or total parenteral nutrition (TPN) fluids due to its name of nutrition therapy. However, IVNT is a fluid treatment method whose composition and purpose are different from amino acid fluids and TPN fluids. IVNT may be applied to alleviating chronic fatigue, liver detoxification, anticancer effects in cancer patients, or relieving side effects from chemotherapy, depending on its components. IVNT can be applied to restore mitochondrial and adrenal dysfunction for alleviating chr

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15

Tan, Angela J. "Car-T cell therapy: T-immunotherapy application in blood cancer." Theoretical and Natural Science 48, no. 1 (2024): 34–39. http://dx.doi.org/10.54254/2753-8818/48/2024pj0125.

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Considering the unsuccessful results and lack of sustainable efficiency of previous cancer therapies, T-immunotherapy's clinical success has led to a revolution in cancer treatments. Blood cancers, characterized by abnormal blood cells and metastasis, result in severe health issues and cause high mortality rates. Conventional treatments like chemotherapy and radiation often result in poor prognoses due to cancer cell resistance and have a high relapse rate. This paper focuses on how Chimeric Antigen Receptor (CAR)-T cell therapy removes tumor cancerous cells with genetically engineered T-cells

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Sargazi, Saman, Ushna Laraib, Simge Er, et al. "Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis." Nanomaterials 12, no. 7 (2022): 1102. http://dx.doi.org/10.3390/nano12071102.

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Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precursors used in plant-based synthesized AuNPs allows for the development of large-scale production in a greener manner. Conventional cancer therapies, such as surgery and chemotherapy, have significant limitations and frequently fail to produce satisfying results. AuNPs have a prolonged circulation time, allow easy modification with ligands

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Yang, Yaoyao, Rui Zhang, Zhiyuan Liang, et al. "Application of Electrospun Drug-Loaded Nanofibers in Cancer Therapy." Polymers 16, no. 4 (2024): 504. http://dx.doi.org/10.3390/polym16040504.

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In the 21st century, chemotherapy stands as a primary treatment method for prevalent diseases, yet drug resistance remains a pressing challenge. Utilizing electrospinning to support chemotherapy drugs offers sustained and controlled release methods in contrast to oral and implantable drug delivery modes, which enable localized treatment of distinct tumor types. Moreover, the core–sheath structure in electrospinning bears advantages in dual-drug loading: the core and sheath layers can carry different drugs, facilitating collaborative treatment to counter chemotherapy drug resistance. This appro

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18

Zhu, Miaomiao. "Application of CRISPR technology in PD-1." Highlights in Science, Engineering and Technology 102 (July 11, 2024): 67–70. http://dx.doi.org/10.54097/jr7ghz06.

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Cancer has been a problem that has plagued human beings for many years. The emergence of immunotherapy that antagonizes antibodies against programmed cell death protein 1 (PD-1) has opened up new ideas for the treatment of different cancers, and the application of CRISPR technology on PD-1 provides new ideas for cancer treatment. However, its potential therapeutic functions and methods have not been fully explored. In this paper, the application of CRISPR technology in PD-1 and more derivative applications will be explored through experiments that study CRISPR-related applications in PD-1. In

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19

Lesmana, Jevon Aaron, and Juandy Jo. "Future Application of Oncolytic Viruses for Cancer Treatment." Medicinus 10, no. 3 (2023): 130. http://dx.doi.org/10.19166/med.v10i3.7037.

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<p>Cancer treatments have developed over the years. A particular improvement is the utilization of oncolytic viruses to treat cancers. Oncolytic viruses are one of the immunotherapeutic tools that potentially could provide good results and benefits to the patients. Oncolytic viruses could mediate antitumor effects. Indeed, the connection between viral infections and cancer treatment have been reported historically. It is known that oncolytic viruses prefer to infect cancer cells rather than normal cells, resulting in the presentation of tumor-associated antigens to the immune system, boo

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20

Liu, Wenhan, Zejun Wang, Yao Luo, and Nan Chen. "Application of Nanocomposites in Cancer Immunotherapy." Nano LIFE 07, no. 03n04 (2017): 1750008. http://dx.doi.org/10.1142/s1793984417500088.

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Despite the clinical advances in oncology, cancer is still the major cause of death worldwide. Recent research demonstrates that the immune system plays a critical role in preventing tumor occurrence and development. The focus on cancer treatment has been shifted from directly targeting the tumor cells to motivating the immune system to achieve this goal. However, the activity of immune system is often suppressed in cancer patients. To boost the anti-tumor immunity against cancers, various nanocomposites have been developed to enhance the efficacy of immunostimulatory agents. Here, we review c

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21

Kim, Jin Hee, Boluwatife Olamide Dareowolabi, Rekha Thiruvengadam, and Eun-Yi Moon. "Application of Nanotechnology and Phytochemicals in Anticancer Therapy." Pharmaceutics 16, no. 9 (2024): 1169. http://dx.doi.org/10.3390/pharmaceutics16091169.

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Cancer is well recognized as a leading cause of mortality. Although surgery tends to be the primary treatment option for many solid cancers, cancer surgery is still a risk factor for metastatic diseases and recurrence. For this reason, a variety of medications has been adopted for the postsurgical care of patients with cancer. However, conventional medicines have shown major challenges such as drug resistance, a high level of drug toxicity, and different drug responses, due to tumor heterogeneity. Nanotechnology-based therapeutic formulations could effectively overcome the challenges faced by

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22

Acheampong, Desmond O. "Bispecific Antibody (bsAb) Construct Formats and their Application in Cancer Therapy." Protein & Peptide Letters 26, no. 7 (2019): 479–93. http://dx.doi.org/10.2174/0929866526666190311163820.

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Development of cancers mostly involves more than one signal pathways, because of the complicated nature of cancer cells. As such, the most effective treatment option is the one that stops the cancer cells in their tracks by targeting these signal pathways simultaneously. This explains why therapeutic monoclonal antibodies targeted at cancers exert utmost activity when two or more are used as combination therapy. This notwithstanding, studies elsewhere have proven that when bispecific antibody (bsAb) is engineered from two conventional monoclonal antibodies or their chains, it produces better a

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23

Premdas, T., A. Vennela, and G. Tejashwini. "Revolutionizing Cancer Treatment: The Role of Nanotechnology in Breast and Colorectal Cancer." Journal of Biomedical and Pharmaceutical Research 14, no. 2 (2025): 9–18. https://doi.org/10.32553/jbpr.v14i2.1254.

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Cancer remains a leading cause of mortality worldwide, with breast and colorectal cancers among the most prevalent. Despite advancements in conventional treatments such as chemotherapy, radiation therapy, and immunotherapy, challenges like systemic toxicity, drug resistance, and lack of targeted therapy persist. Nanotechnology has emerged as a promising approach in oncology, offering precise drug delivery, improved bioavailability, and reduced side effects. This review explores the role of nanotechnology in breast and colorectal cancer treatment, focusing on recent advancements in drug deliver

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24

Pinkawa, Michael. "Spacer application for prostate cancer radiation therapy." Future Oncology 10, no. 5 (2014): 851–64. http://dx.doi.org/10.2217/fon.13.223.

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25

Vetvicka, Vaclav. "Syntetic Oligosacharides – Clinical Application in Cancer Therapy." Anti-Cancer Agents in Medicinal Chemistry 13, no. 5 (2013): 720–24. http://dx.doi.org/10.2174/1871520611313050006.

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26

Furusawa, Yoshiya. "Application of Quantum Beam for Cancer Therapy." IEEJ Transactions on Electronics, Information and Systems 137, no. 3 (2017): 390–93. http://dx.doi.org/10.1541/ieejeiss.137.390.

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27

Enriquez-Navas, Pedro M., Jonathan W. Wojtkowiak, and Robert A. Gatenby. "Application of Evolutionary Principles to Cancer Therapy." Cancer Research 75, no. 22 (2015): 4675–80. http://dx.doi.org/10.1158/0008-5472.can-15-1337.

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28

Cianfrocca, Mary. "Application of epothilones in breast cancer therapy." Current Opinion in Oncology 20, no. 6 (2008): 634–38. http://dx.doi.org/10.1097/cco.0b013e32831270b0.

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29

Liang, Danna, Qingfei Zhang, Xiang Chen, Jianhua Lu, Xian Shen, and Weijian Sun. "Application of gas molecules in cancer therapy." Biomedical Technology 6 (June 2024): 46–60. http://dx.doi.org/10.1016/j.bmt.2023.11.001.

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30

Rivas, J., M. Bañobre-López, Y. Piñeiro-Redondo, B. Rivas, and M. A. López-Quintela. "Magnetic nanoparticles for application in cancer therapy." Journal of Magnetism and Magnetic Materials 324, no. 21 (2012): 3499–502. http://dx.doi.org/10.1016/j.jmmm.2012.02.075.

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YUHAS, JOHN M., ROBERT L. GOODMAN, and ROBERT E. MOORE. "Potential Application of Perfluorochemicals in Cancer Therapy." International Anesthesiology Clinics 23, no. 1 (1985): 199–210. http://dx.doi.org/10.1097/00004311-198502310-00018.

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Sun, Qiuyang, Yu Han, Yuming Yang, Jesús M. de la Fuente, Daxiang Cui, and Xiaoqiang Wang. "Application of DNA nanostructures in cancer therapy." Applied Materials Today 21 (December 2020): 100861. http://dx.doi.org/10.1016/j.apmt.2020.100861.

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33

Mulé, J. J., S. G. Marcus, J. C. Yang, J. S. Weber, and S. A. Rosenberg. "Clinical application of IL6 in cancer therapy." Research in Immunology 143, no. 7 (1992): 777–83. http://dx.doi.org/10.1016/0923-2494(92)80023-e.

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34

Liu, Dan. "Application of EGFR targeted therapy in cancer." Precision Medicine Research 1, no. 1 (2019): 2–8. http://dx.doi.org/10.53388/pmr201900002.

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35

Riggio, Cristina, Eleonora Pagni, Vittoria Raffa, and Alfred Cuschieri. "Nano-Oncology: Clinical Application for Cancer Therapy and Future Perspectives." Journal of Nanomaterials 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/164506.

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Nano-oncology, the application of Nanomedicine to cancer diagnosis and treatment, has the potential to transform clinical oncology by enhancing the efficacy of cancer chemotherapy for a wide spectrum of invasive cancers. It achieves this by enabling novel drug delivery systems which target the tumour site with several functional molecules, including tumour-specific ligands, antibodies, cytotoxic agents, and imaging probes simultaneously thereby improving tumour response rates in addition to significant reduction of the systemic toxicity associated with current chemotherapy regimens. For this r

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Pramiasti, Hana Dodik, Agung Waluyo, and Yati Afiyanti. "Aplikasi Smartphone sebagai Sarana Promosi Kesehatan Kanker dengan Terapi Radiasi." Journal of Telenursing (JOTING) 4, no. 1 (2022): 252–61. http://dx.doi.org/10.31539/joting.v4i1.3544.

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This study aims to determine the benefits of using smartphone applications in the health sector in increasing the knowledge of patients or survivors about cancer health, prevention, early detection and screening of cancer, especially treatment with radiation modalities. The method used is PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) on several electronic databases through screening titles about cancer education or health promotion with radiation therapy. The results showed that many smartphone applications in the field of cancer services were used in patients rec

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Vodyashkin, Andrey A., Marko George Halim Rizk, Parfait Kezimana, Anatoly A. Kirichuk, and Yaroslav M. Stanishevskiy. "Application of Gold Nanoparticle-Based Materials in Cancer Therapy and Diagnostics." ChemEngineering 5, no. 4 (2021): 69. http://dx.doi.org/10.3390/chemengineering5040069.

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Several metal nanoparticles have been developed for medical application. While all have their benefits, gold nanoparticles (AuNPs) are ideal in cancer therapy and diagnosis as they are chemically inert and minimally toxic. Several studies have shown the potential of AuNPs in the therapeutic field, as photosensitizing agents in sonochemical and photothermal therapy and as drug delivery, as well as in diagnostics and theranostics. Although there is a significant number of reviews on the application of AuNPs in cancer medicine, there is no comprehensive review on their application both in therapy

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Liang, Ziyue. "Metformin: exploring its potential as an anticancer drug." Theoretical and Natural Science 66, no. 1 (2024): 97–102. https://doi.org/10.54254/2753-8818/2024.18042.

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Metformin is a commonly used hypoglycemic agent that has received much attention in recent years for its potential in cancer therapy. This paper reviews and concludes the anti-cancer mechanisms of metformin and its clinical applications in different cancer types. It was found that metformin indirectly inhibits cancer cell growth by activating AMPK and inhibiting the mTOR pathway and decreasing insulin and IGF-1 levels. In addition, metformin directly inhibits cancer cell proliferation by inducing apoptosis and autophagy. Clinical data suggest that metformin significantly improves survival and

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Chen, Mengfei, Haoze Li, and Yinxuan Wu. "Development and Clinical Application of CAR-T Therapy." Highlights in Science, Engineering and Technology 36 (March 21, 2023): 1269–76. http://dx.doi.org/10.54097/hset.v36i.6226.

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The problem of cancer is becoming more and more serious. As of 2021, the global of cancer patients has reached 14 million. Now how to treat cancer has become one of the key research topics. To treat cancer, people have found many cure methods, like salvage chemotherapy, radiotherapy, cytotoxic chemotherapy, and so on. But these therapies can only delay the patient's life. They cannot cure cancer. People want to find a therapy to completely empty the cancer cells. Until 1989, scientists have found a way to engineer T-cell called Chimeric antigen receptor T cell (CAR-T) to attack cancer cells, C

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Yamano, Seiichi, Kenji Inoue, and Yoichiro Taguchi. "Application of Gene Therapy to Oral Diseases." Pharmaceutics 17, no. 7 (2025): 859. https://doi.org/10.3390/pharmaceutics17070859.

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Gene therapy has emerged as a promising therapeutic approach across various oral diseases. This review examines current applications and future prospects of gene therapy in dentistry, focusing on five key areas: oral cancer, cancer-related pain, xerostomia (dry mouth), dental caries, and periodontal disease. Recent advances in viral and non-viral vectors have enabled more efficient gene delivery systems, with particular success in cancer pain management through µ-opioid receptor gene transfer and xerostomia treatment using aquaporin-1 gene therapy. For periodontal applications, gene therapy st

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Boopathi, Ettickan, and Chellappagounder Thangavel. "Dark Side of Cancer Therapy: Cancer Treatment-Induced Cardiopulmonary Inflammation, Fibrosis, and Immune Modulation." International Journal of Molecular Sciences 22, no. 18 (2021): 10126. http://dx.doi.org/10.3390/ijms221810126.

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Advancements in cancer therapy increased the cancer free survival rates and reduced the malignant related deaths. Therapeutic options for patients with thoracic cancers include surgical intervention and the application of chemotherapy with ionizing radiation. Despite these advances, cancer therapy-related cardiopulmonary dysfunction (CTRCPD) is one of the most undesirable side effects of cancer therapy and leads to limitations to cancer treatment. Chemoradiation therapy or immunotherapy promote acute and chronic cardiopulmonary damage by inducing reactive oxygen species, DNA damage, inflammati

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Siddique, Sarkar, and James C. L. Chow. "Application of Nanomaterials in Biomedical Imaging and Cancer Therapy." Nanomaterials 10, no. 9 (2020): 1700. http://dx.doi.org/10.3390/nano10091700.

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Nanomaterials, such as nanoparticles, nanorods, nanosphere, nanoshells, and nanostars, are very commonly used in biomedical imaging and cancer therapy. They make excellent drug carriers, imaging contrast agents, photothermal agents, photoacoustic agents, and radiation dose enhancers, among other applications. Recent advances in nanotechnology have led to the use of nanomaterials in many areas of functional imaging, cancer therapy, and synergistic combinational platforms. This review will systematically explore various applications of nanomaterials in biomedical imaging and cancer therapy. The

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Zhu, Liangxi, Jingzhou Zhao, Zhukang Guo, et al. "Applications of Aptamer-Bound Nanomaterials in Cancer Therapy." Biosensors 11, no. 9 (2021): 344. http://dx.doi.org/10.3390/bios11090344.

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Cancer is still a major disease that threatens human life. Although traditional cancer treatment methods are widely used, they still have many disadvantages. Aptamers, owing to their small size, low toxicity, good specificity, and excellent biocompatibility, have been widely applied in biomedical areas. Therefore, the combination of nanomaterials with aptamers offers a new method for cancer treatment. First, we briefly introduce the situation of cancer treatment and aptamers. Then, we discuss the application of aptamers in breast cancer treatment, lung cancer treatment, and other cancer treatm

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Biedka-Paluch, Marta, Patryk Leszek Biedka, and Beata Januszko-Giergielewicz. "Potential application of stereotactic radiotherapy in head and neck cancer." Acta Elbingensia 51, no. 1 (2024): 14–22. https://doi.org/10.61785/ael/199674.

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IntroductionStereotactic ablative radiation (SABR) therapy, or stereotactic body radiation therapy (SBRT), delivers high-dose external beam radiation to a small, clearly defined target area in one or more sessions. It is the standard treatment for medically inoperable early-stage non-small cell lung cancer, early-stage prostate cancer, and oligometastatic disease from other primary locations.AimThis article discusses the use of stereotactic radiotherapy in neoplasms of the head and neck region – as primary treatment, including early laryngeal cancer; as post-operative adjuvant therapy; as a bo

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Luo, Xinyu. "Application of Cytokines in the Treatment of Lung Cancer." Highlights in Science, Engineering and Technology 102 (July 11, 2024): 644–51. http://dx.doi.org/10.54097/f0bs8c02.

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Lung cancer is one of the malignant tumors with a high incidence rate and mortality worldwide. Cytokines are a crucial component of the human immune system. In cancer treatment, cytokine-based cancer immunotherapy has shown promising clinical prospects. It is worth noting that over the past few decades, there has been extensive research on cytokines and their receptors as targets for cancer or cancer treatment methods. As proteins in the immune system, interleukin, interferons, and other cytokines play crucial roles in controlling the body's immunological response to cancer cells and triggerin

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Pokrovsky, Vadim S., Olga E. Chepikova, Denis Zh Davydov, Andrey A. Zamyatnin Jr, Alexander N. Lukashev, and Elena V. Lukasheva. "Amino Acid Degrading Enzymes and their Application in Cancer Therapy." Current Medicinal Chemistry 26, no. 3 (2019): 446–64. http://dx.doi.org/10.2174/0929867324666171006132729.

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Background:Amino acids are essential components in various biochemical pathways. The deprivation of certain amino acids is an antimetabolite strategy for the treatment of amino acid-dependent cancers which exploits the compromised metabolism of malignant cells. Several studies have focused on the development and preclinical and clinical evaluation of amino acid degrading enzymes, namely L-asparaginase, L-methionine γ-lyase, L-arginine deiminase, L-lysine α-oxidase. Further research into cancer cell metabolism may therefore define possible targets for controlling tumor growth.Objective:The purp

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Xiao, Dexuan, and Ronghui Zhou. "Advances in the Application of Liposomal Nanosystems in Anticancer Therapy." Current Stem Cell Research & Therapy 16, no. 1 (2021): 14–22. http://dx.doi.org/10.2174/1574888x15666200423093906.

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Cancer is the disease with the highest mortality rate, which poses a great threat to people’s lives. Cancer caused approximately 3.4 million death worldwide annually. Surgery, chemotherapy and radiotherapy are the main therapeutic methods in clinical practice. However, surgery is only suitable for patients with early-stage cancers, and chemotherapy as well as radiotherapy have various side effects, both of which limit the application of available therapeutic methods. In 1965, liposome was firstly developed to form new drug delivery systems given the unique properties of nanoparticles, such as

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Wang, Zhouyao. "Applications of Polymers for Drug Delivery, Cancer Therapy and Antibacterial." Highlights in Science, Engineering and Technology 11 (August 23, 2022): 100–106. http://dx.doi.org/10.54097/hset.v11i.1271.

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The mortality rate of cancer is gradually increasing every year. The application of polymers in biomedicine is one of the key research directions today. A number of researchers have found that polymers have great potential in chemotherapy, yet there is a research gap regarding the toxicity of the drugs to patients. Therefore, this research will introduce the application of a diverse of different polymer materials in biomedicine. Specifically, this research will mainly demonstrate the application of functional polymer materials in the following aspects, including drug delivery, anti-cancer, and

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Sheng, Sifei. "Gene Therapy and Its Application in Breast Cancer Treatment." Transactions on Materials, Biotechnology and Life Sciences 7 (December 24, 2024): 7–11. https://doi.org/10.62051/4f8v7r16.

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As a new medical field, gene therapy has shown great potential in cancer treatment. This article reviews the principle, mechanism and application of gene therapy in the treatment of breast cancer, and discusses the prospect and challenge of its future development. Mutation, as the common cause of cancer, is the target of gene therapy. By replacing disease-causing genes, suppressing malfunctioning genes, or introducing new genes, a variety of mutation caused disease could be treated... In particular, this paper presents genome editing technologies such as CRISPR-Cas9, which correct genetic diff

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Uthappa, Uluvangada Thammaiah, Maduru Suneetha, Kanalli V. Ajeya, and Seong Min Ji. "Hyaluronic Acid Modified Metal Nanoparticles and Their Derived Substituents for Cancer Therapy: A Review." Pharmaceutics 15, no. 6 (2023): 1713. http://dx.doi.org/10.3390/pharmaceutics15061713.

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The use of metal nanoparticles (M-NPs) in cancer therapy has gained significant consideration owing to their exceptional physical and chemical features. However, due to the limitations, such as specificity and toxicity towards healthy cells, their application in clinical translations has been restricted. Hyaluronic acid (HA), a biocompatible and biodegradable polysaccharide, has been extensively used as a targeting moiety, due to its ability to selectively bind to the CD44 receptors overexpressed on cancer cells. The HA-modified M-NPs have demonstrated promising results in improving specificit

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