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Journal articles on the topic '-approximately 1395'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 July 2024

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1

McDonnell, Mark, Dirk Van Genechten, Teodora Kolarova, Dermot O'Toole, Harjit Singh, Jie Chen, James R. Howe, et al. "Survey of challenges in access to diagnostics and treatment for neuroendocrine tumor (NET) patients (SCAN): Awareness of specialized techniques and latest interventions." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e16708-e16708. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16708.

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e16708 Background: SCAN measured global readiness to provide diagnostics and treatments for NET patients in terms of awareness, availability, quality and affordability. This analysis focused on patient and healthcare professional (HCP) awareness of NET diagnostics and treatments. Methods: During Sept-Nov 2019, NET patients and HCPs completed an online survey (available in 14 languages). Results: There were 2795 respondents from 68 countries across 6 continents (2359 patients/carers; 436 HCPs). Primary NETs were most often gastroenteropancreatic NETs (GEP NET; 71% [1408/1983]), particularly small intestinal (35% [690/1983]) or pancreatic (20% [402/1983]). Biopsy was the most well-known diagnostic option in the overall NET patient group (82% [1917/2325]), the GEP NET patient subgroup (83% [1156/1395]) and HCPs (94% [411/435]), followed by CT (all patients: 81% [1874/2325]; GEP NET: 80% [1118/1395]; HCPs: 86% [376/435]). More HCPs were aware of specialized diagnostics, such as 68Ga-DOTA PET CT (HCP 81% [353/435]) and chromogranin A (CgA; 79% [344/435]), than patients (all: 68% [1574/2325] & 62% [1451/2325], respectively; GEP NET: 69% [962/1395] & 67% [936/1395]). The vast majority of all patients (87% [1983/2275]), GEP NET patients (89% [1215/1363]) and HCPs (91% [392/431]) knew surgery was a treatment option. Somastatin analogues were recognised as a treatment option by 90% of HCPs (387/431), but only 75% of GEP NET patients (1019/1363) and 70% of all NET patients (1599/2275). Nearly a quarter of HCPs (22% [95/431]) and one-third of patients (all: 33% [755/2275]; GEP NET: 30% [409/1363]) had not heard of peptide receptor radionuclide therapy (PRRT). The majority of patients (all: 88% [2007/2273]; GEP NET: 89% [1213/1370]) and HCPs (93% [396/425]) were aware of conventional imaging, such as CT/MRI/ultrasound, being used for ongoing monitoring of NETs. Approximately a third of all NET patients and a quarter of HCPs were unware CgA (patients: 32% [723/2273]; HCPs: 22% [94/425]) or 68Ga-DOTA PET CT (patients: 29% [670/2273]; HCPs: 24% [102/425]) were ongoing monitoring tools. Similarly, CgA and 68Ga-DOTA PET CT were not recognized by 27% of GEP NET patients (364/1370 & 371/1370, respectively). Conclusions: Increased awareness of NET diagnostics and treatments, particularly newer, more specialized tools, amongst both HCPs and patients is required to ensure continued advancements and improvements in the global standard of care for NETs.

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PLANT, A. J., R. E. WATKINS, B. GUSHULAK, T. O'ROURKE, W. JONES, J. STREETON, and D. SANG. "Predictors of tuberculin reactivity among prospective Vietnamese migrants: the effect of smoking." Epidemiology and Infection 128, no. 1 (February 2002): 37–45. http://dx.doi.org/10.1017/s0950268801006434.

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We investigated the prevalence and predictors of positive tuberculin skin test (TST) results among prospective Vietnamese migrants. We interviewed and medically screened 1395 Vietnamese people aged over 15 years who had applied to migrate to Australia. Approximately 44% of applicants had an induration of 10 mm or more, and 18·6% had an induration of 15 mm or more. A positive tuberculin skin test at 5 mm, 10 mm and 15 mm of induration cut-points was significantly associated with age (OR 1·01–1·02 per year) and duration of smoking (OR 1·03–1·12 per year). Smoking appears to be an important factor associated with increased susceptibility to mycobacterial infection. It is not yet clear whether the increased tuberculin reactivity associated with smoking reflects an increased risk of tuberculosis among these migrants.

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Colgan, W., W. T. Pfeffer, H. Rajaram, W. Abdalati, and J. Balog. "Monte Carlo ice flow modeling projects a new stable configuration for Columbia Glacier, Alaska, c. 2020." Cryosphere 6, no. 6 (November 26, 2012): 1395–409. http://dx.doi.org/10.5194/tc-6-1395-2012.

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Abstract. Due to the abundance of observational datasets collected since the onset of its retreat (c. 1983), Columbia Glacier, Alaska, provides an exciting modeling target. We perform Monte Carlo simulations of the form and flow of Columbia Glacier, using a 1-D (depth-integrated) flowline model, over a wide range of parameter values and forcings. An ensemble filter is imposed following spin-up to ensure that only simulations that accurately reproduce observed pre-retreat glacier geometry are retained; all other simulations are discarded. The selected ensemble of simulations reasonably reproduces numerous highly transient post-retreat observed datasets. The selected ensemble mean projection suggests that Columbia Glacier will achieve a new dynamic equilibrium (i.e. "stable") ice geometry c. 2020, at which time iceberg calving rate will have returned to approximately pre-retreat values. Comparison of the observed 1957 and 2007 glacier geometries with the projected 2100 glacier geometry suggests that Columbia Glacier had already discharged ~82% of its projected 1957–2100 sea level rise contribution by 2007. This case study therefore highlights the difficulties associated with the future extrapolation of observed glacier mass loss rates that are dominated by iceberg calving.

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van Os, Jim, Lotta-Katrin Pries, Margreet ten Have, Ron de Graaf, Saskia van Dorsselaer, Maarten Bak, Hans-Ulrich Wittchen, Bart P. F. Rutten, and Sinan Guloksuz. "Schizophrenia and the Environment: Within-Person Analyses May be Required to Yield Evidence of Unconfounded and Causal Association—The Example of Cannabis and Psychosis." Schizophrenia Bulletin 47, no. 3 (March 8, 2021): 594–603. http://dx.doi.org/10.1093/schbul/sbab019.

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Abstract Hypotheses about the link between cannabis use and psychosis apply to the within-person level but have been tested mostly at the between-person level. We used a within-person design, in which a person serves as his own control, thus removing the need to consider confounding by any fixed (genetic and nongenetic) characteristic to study the prospective association between cannabis use and the incidence of attenuated psychotic experiences, and vice versa, adjusted for time-varying confounders. We combined 2 general population cohorts (at baseline: Early Developmental Stages of Psychopathology Study, n = 1395; Netherlands Mental Health Survey and Incidence Study-2, n = 6603), which applied a similar methodology to study cannabis use and attenuated psychotic experiences with repeated interviews (T0, T1, T2, and T3) over a period of approximately 10 years. The Hausman test was significant for the adjusted models, indicating the validity of the fixed-effects model. In the adjusted fixed-effects model, prior cannabis use was associated with psychotic experiences (aOR = 7.03, 95% CI: 2.39, 20.69), whereas prior psychotic experiences were not associated with cannabis use (aOR = 0.59, 95% CI: 0.21, 1.71). Longitudinal studies applying random-effects models to study associations between risk factors and mental health outcomes, as well as reverse causality, may not yield precise estimates. Cannabis likely impacts causally on psychosis but not the other way round.

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Mamaloukas-Frangoulis, Vassilios, Polychronopoulos Helen, Ploumitsakos Kostas, and Volakis Stelios. "THE SUCCESSFUL OIL REMOVAL OPERATION FROM THE SUNKEN VESSEL JUPITER IN GREECE." International Oil Spill Conference Proceedings 2001, no. 2 (March 1, 2001): 1395–97. http://dx.doi.org/10.7901/2169-3358-2001-2-1395.

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ABSTRACT A significant oil leakage from the wreck of the passenger vessel Jupiter occurred in the proximity of Piraeus Port Entrance in Greece on September 9, 1999, caused probably by a major earthquake. Eleven years earlier, the vessel had sunk after a severe collision, with a considerable quantity of fuels and lubricants onboard. Underwater research revealed that the wreck was lying on the seabed at a depth of 75 meters and a distance of 1.2 nautical miles from the port entrance, within the traffic lines of ships while the oil was found to leak from several portholes and a watertight cargo door. After the responsible state authorities decided to remove oil from the wreck, preparatory work was initiated including the detection and marking of the exact position of fuel tanks and all leaking points, while a series of precautionary measures were implemented to ensure safety of navigation and the recovery of any accidental oil escape from the wreck. Using hot tapping technique, the oil remaining in fuel tanks was pumped out. Furthermore, oil entrapped in accommodations and other spaces was pumped out and released with use of compressed air. The whole operation lasted 43 days and resulted in the pumping out of approximately 1,225 barrels of oil and oily residues, and the subsequent effective protection of the wider marine area.

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Safley, Anne M., Patrick J. Buckley, Andrew J. Creager, Rajesh C. Dash, Leslie G. Dodd, Barbara K. Goodman, Claudia K. Jones, et al. "The Value of Fluorescence In Situ Hybridization and Polymerase Chain Reaction in the Diagnosis of B-Cell Non-Hodgkin Lymphoma by Fine-Needle Aspiration." Archives of Pathology & Laboratory Medicine 128, no. 12 (December 1, 2004): 1395–403. http://dx.doi.org/10.5858/2004-128-1395-tvofis.

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Abstract Context.—Molecular genetic analyses have been predicted to improve the diagnostic accuracy of fine-needle aspiration of B-cell non-Hodgkin lymphoma. Objective.—To determine the value of routine molecular genetic assays, polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH), in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspiration (FNA). Design.—A multiparametric method, including cytology, flow cytometry, PCR, and FISH, was prospectively evaluated in the diagnosis of B-cell non-Hodgkin lymphoma by FNA. Aspirates from 30 consecutive patients with suspected hematolymphoid malignancies were collected. All aspirates were triaged through a uniform program including cell-size analysis, B- and T-cell clonality studies, flow cytometric immunophenotyping, and bcl-1 and bcl-2 gene rearrangements by PCR and FISH. After completion of FNA evaluations, FNA results were compared with diagnoses from prior or subsequent surgical biopsies. Results.—Monoclonal B-cell populations were detected in 18 of 20 B-cell non-Hodgkin lymphomas by flow cytometry and PCR. bcl-1 gene rearrangement was detected in 2 of 2 cases of mantle cell lymphoma. bcl-2 rearrangement was detected in 5 cases including 4 of 4 low-grade follicular lymphomas and 1 transformed follicular lymphoma. By incorporating the results of molecular genetic and ancillary diagnostics, a definitive classification was reached in 12 cases of B-cell non-Hodgkin lymphoma by FNA, including all cases of low-grade follicular lymphoma (4/4) and mantle cell lymphoma (2/2) and approximately 50% of small lymphocytic lymphoma (2/4) and large B-cell lymphoma (4/8). Ten of the 12 cases with a final classification reached by FNA had either prior or follow-up surgical biopsies, and all 10 cases showed agreement between the diagnoses rendered on FNA and surgical biopsies. Conclusions.—With proper handling and management of specimens, FNA can routinely provide samples adequate for molecular genetic studies, in addition to cytomorphology and flow cytometry, making it possible to consistently render accurate and definitive diagnoses in a subset of B-cell non-Hodgkin lymphomas. By incorporating FISH and PCR methods, FNA may assume an expanded role for the primary diagnosis of B-cell non-Hodgkin lymphoma.

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Tijssen, M. J. A., J. van Os, H. U. Wittchen, R. Lieb, K. Beesdo, R. Mengelers, L. Krabbendam, and M. Wichers. "Evidence that bipolar disorder is the poor outcome fraction of a common developmental phenotype: an 8-year cohort study in young people." Psychological Medicine 40, no. 2 (June 11, 2009): 289–99. http://dx.doi.org/10.1017/s0033291709006138.

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BackgroundReported rates of bipolar syndromes are highly variable between studies because of age differences, differences in diagnostic criteria, or restriction of sampling to clinical contacts.MethodIn 1395 adolescents aged 14–17 years, DSM-IV (hypo)manic episodes (manic and hypomanic episodes combined), use of mental health care, and five ordinal subcategories representing the underlying continuous score of (hypo)manic symptoms (‘mania symptom scale’) were measured at baseline and approximately 1.5, 4 and 10 years later using the Munich-Composite International Diagnostic Interview (DIA-X/M-CIDI).ResultsIncidence rates (IRs) of both (hypo)manic episodes and (hypo)manic symptoms (at least one DSM-IV core symptom) were far higher (714/105 person-years and 1720/105 person-years respectively) than traditional estimates. In addition, the risk of developing (hypo)manic episodes was very low after the age of 21 years [hazard ratio (HR) 0.031, 95% confidence interval (CI) 0.0050–0.19], independent of childhood disorders such as attention deficit hyperactivity disorder (ADHD). Most individuals with hypomanic and manic episodes were never in care (87% and 62% respectively) and not presenting co-morbid depressive episodes (69% and 60% respectively). The probability of mental health care increased linearly with the number of symptoms on the mania symptom scale. The incidence of the bipolar categories, in particular at the level of clinical morbidity, was strongly associated with previous childhood disorders and male sex.ConclusionsThis study showed, for the first time, that experiencing (hypo)manic symptoms is a common adolescent phenomenon that infrequently predicts mental health care use. The findings suggest that the onset of bipolar disorder can be elucidated by studying the pathway from non-pathological behavioural expression to dysfunction and need for care.

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Lockwood, M., R. B. Forsyth, A. Balogh, and D. J. McComas. "Open solar flux estimates from near-Earth measurements of the interplanetary magnetic field: comparison of the first two perihelion passes of the Ulysses spacecraft." Annales Geophysicae 22, no. 4 (April 2, 2004): 1395–405. http://dx.doi.org/10.5194/angeo-22-1395-2004.

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Abstract. Results from all phases of the orbits of the Ulysses spacecraft have shown that the magnitude of the radial component of the heliospheric field is approximately independent of heliographic latitude. This result allows the use of near-Earth observations to compute the total open flux of the Sun. For example, using satellite observations of the interplanetary magnetic field, the average open solar flux was shown to have risen by 29% between 1963 and 1987 and using the aa geomagnetic index it was found to have doubled during the 20th century. It is therefore important to assess fully the accuracy of the result and to check that it applies to all phases of the solar cycle. The first perihelion pass of the Ulysses spacecraft was close to sunspot minimum, and recent data from the second perihelion pass show that the result also holds at solar maximum. The high level of correlation between the open flux derived from the various methods strongly supports the Ulysses discovery that the radial field component is independent of latitude. We show here that the errors introduced into open solar flux estimates by assuming that the heliospheric field's radial component is independent of latitude are similar for the two passes and are of order 25% for daily values, falling to 5% for averaging timescales of 27 days or greater. We compare here the results of four methods for estimating the open solar flux with results from the first and second perehelion passes by Ulysses. We find that the errors are lowest (1–5% for averages over the entire perehelion passes lasting near 320 days), for near-Earth methods, based on either interplanetary magnetic field observations or the aa geomagnetic activity index. The corresponding errors for the Solanki et al. (2000) model are of the order of 9–15% and for the PFSS method, based on solar magnetograms, are of the order of 13–47%. The model of Solanki et al. is based on the continuity equation of open flux, and uses the sunspot number to quantify the rate of open flux emergence. It predicts that the average open solar flux has been decreasing since 1987, as is observed in the variation of all the estimates of the open flux. This decline combines with the solar cycle variation to produce an open flux during the second (sunspot maximum) perihelion pass of Ulysses which is only slightly larger than that during the first (sunspot minimum) perihelion pass. Key words. Interplanetary physics (interplanetary magnetic fields) – Solar physics, astrophysics and astronomy (magnetic fields)

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Bednar, J., R. A. Horowitz, J. Dubochet, and C. L. Woodcock. "Chromatin conformation and salt-induced compaction: three-dimensional structural information from cryoelectron microscopy." Journal of Cell Biology 131, no. 6 (December 15, 1995): 1365–76. http://dx.doi.org/10.1083/jcb.131.6.1365.

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Cryoelectron microscopy has been used to examine the three-dimensional (3-D) conformation of small oligonucleosomes from chicken erythrocyte nuclei after vitrification in solutions of differing ionic strength. From tilt pairs of micrographs, the 3-D location and orientation of the nucleosomal disks, and the paths of segments of exposed linker can be obtained. In "low-salt" conditions (5 mM NaCl, 1 mM EDTA, pH 7.5), the average trinucleosome assumes the shape of an equilateral triangle, with nucleosomes at the vertices, and a length of exposed linker DNA between consecutive nucleosomes equivalent to approximately 46 bp. The two linker DNA segments converge at the central nucleosome. Removal of histones H1 and H5 results in a much more variable trinucleosome morphology, and the two linker DNA segments usually join the central nucleosome at different locations. Trinucleosomes vitrified in 20 mM NaCl, 1 mM EDTA, (the salt concentration producing the maximal increase in sedimentation), reveal that compaction occurs by a reduction in the included angle made by the linker DNA segments at the central nucleosome, and does not involve a reduction in the distance between consecutive nucleosomes. Frequently, there is also a change in morphology at the linker entry-exit site. At 40 mM NaCl, there is no further change in trinucleosome morphology, but polynucleosomes are appreciably more compact. Nevertheless, the 3-D zig-zag conformation observed in polynucleosomes at low salt is retained at 40 mM NaCl, and individual nucleosome disks remain separated from each other. There is no evidence for the formation of solenoidal arrangements within polynucleosomes. Comparison of the solution conformation of individual oligonucleosomes with data from physical measurements on bulk chromatin samples suggests that the latter should be reinterpreted. The new data support the concept of an irregular zig-zag chromatin conformation in solution over a range of ionic strengths, in agreement with other in situ (McDowall, A.W., J.M. Smith, and J. Dubochet. 1986, EMBO (Eur. Mol. Biol. Organ.) J.5: 1395-1402; Horowitz, R.A., D.A. Agard, J.W. Sedat, and C.L. Woodcock, 1994. J. Cell Biol. 125:1-10), and in vitro conclusions (van Holde, K., and J. Zlatanova. 1995. J. Biol. Chem. 270:8373-8376). Cryoelectron microscopy also provides a way to determine the 3-D conformation of naturally occurring chromatins in which precise nucleosome positioning plays a role in transcriptional regulation.

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Fülesdi, Béla, Calin Mitre, and Csilla Molnár. "Parkinson-kórban szenvedő betegek perioperatív ellátása. Irodalmi összefoglaló." Orvosi Hetilap 156, no. 34 (August 2015): 1355–59. http://dx.doi.org/10.1556/650.2015.30233.

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Similarly to an increase in life expectancy, the incidence of Parkinson’s disease increases as well. In parallel with this, more patients with Parkinson’s disease undergo elective or urgent surgical interventions. According to recent statistical data, more than half of the patients with Parkinson’s disease are not properly managed when they are hospitalized for surgical interventions. It is also clear that properly managed Parkinson’s disease patients have an approximately 50% lower rate for perioperative complications. The authors aimed to summarize the most important complications, the updated peri- and intraoperative treatment and management strategies of patients with Parkinson’s disease. They intended to underline that interdisciplinary cooperation and knowledge of the proper strategy may result in more successful treatment of Parkinson’s disease patients during the perioperative period. Orv. Hetil., 2015, 156(34), 1355–1359.

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Ko, Y., C. Y. Chen, K. S. Yao, C. W. Liu, S. Maruthasalam, and C. H. Lin. "First Report of Fruit Rot of Strawberry Caused by an Alternaria sp. in Taiwan." Plant Disease 92, no. 8 (August 2008): 1248. http://dx.doi.org/10.1094/pdis-92-8-1248b.

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In March 2005, a fruit rot disease was found in several commercial strawberry (Fragaria × ananassa Duchesne) fields at Fongyuan, 24.25°N, 120.72°E, in Taichung County in central Taiwan. The disease was rare and was negligible in most cultivated areas. However, disease incidence has increased by 4 to 5% over the last 2 years and causes significant postharvest losses. In storage, symptoms on berries include light brown-to-black, sunken, irregularly shaped lesions. The lesions gradually enlarge and become firm with a dark green-to-black, velvety surface composed of mycelia, conidiophores, and conidia. Twelve single conidial isolates (AF-1 to AF-12) of a fungus were isolated by placing portions of symptomatic fruit from four locations onto acidified potato dextrose agar (PDA) and incubating at 24 ± 1°C. One isolate from each of the four locations, AF-2, 6, 9, and 12, was selected for identification and pathogenicity studies. The fungus was identified as an Alternaria sp. according to the morphological descriptions of A. tenuissima (2,3). Conidiophores were simple or branched, straight or flexuous, septate, pale to light brown, 3.0 to 5.0 μm in diameter, and bore two to six conidia in a chain. Conidia were dark brown, obclavate or oval, and multicellular with seven transverse (in most cases) and numerous longitudinal septa. Conidia were 15.5 to 56.5 μm (average 35.0 μm) long × 6.0 to 15.0 μm (average 11.0 μm) wide at the broadest point. The pathogen was consistently isolated from berries in the field or in storage. Pathogenicity tests were conducted by inoculating 12 surface-sterilized berries with each of the four isolates. Approximately 300 μl of a spore suspension (2 × 105 conidia per ml) was placed at two points on the uninjured surface of each fruit and allowed to dry for 5 min. Control fruits were treated with sterile water. The berries were then enclosed in a plastic bag and incubated at 24 ± 1°C for 2 days. Disease symptoms similar to those described above were observed on 95% of inoculated berries 3 days after inoculation, while no symptoms developed in control berries. Reisolation from the inoculated berries consistently yielded the Alternaria sp. described above. Pathogenicity tests were performed three times. Previously, strawberry fruit rot caused by A. tenuissima was reported from Florida (2) and Malaysia (1), however, to our knowledge, this is the first report of fruit rot of strawberry caused by a species of Alternaria in Taiwan. References: (1) W. D. Cho et al. List of Plant Diseases in Korea. Korean Society of Plant Pathology, 2004. (2) C. M. Howard and E. E. Albregts. Phytopathology 63:938, 1973. (3) R. D. Milholland. Phytopathology 63:1395, 1973.

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Shah, Nina, Donna M. Weber, Michael Wang, Sheeba Thomas, Jatin Shah, Sergio Giralt, Raymond Alexanian, Robert Z. Orlowski, Muzaffar H. Qazilbash, and Tiffany Avery. "Survival Disparities Between African-American and Caucasian Patients with Multiple Myeloma Are Blunted in the Era of Novel Therapeutics and Autologous Stem Cell Transplantation." Blood 114, no. 22 (November 20, 2009): 1395. http://dx.doi.org/10.1182/blood.v114.22.1395.1395.

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Abstract Abstract 1395 Poster Board I-417 Background: Multiple myeloma accounts for approximately 10% of hematologic malignancies diagnosed annually in the U.S. It is well documented that the African-American population is disproportionately affected by multiple myeloma in incidence and mortality. Survival data from the SEER database from 2001-2005 demonstrated higher mortality in African-American patients compared to Caucasian patients. However, more recent retrospective reviews in the era of autologous stem cell transplant (ASCT) did not support this finding. Thus the persistence of racial survival disparities in the era of ASCT and novel therapeutics is an evolving question. Methods: We performed a retrospective review of 170 African-American multiple myeloma patients and 170 age and gender-matched Caucasian patients initially seen at the M.D. Anderson Cancer Center from 1/1/2002 to 12/31/2008. Results: Three hundred forty previously untreated patients were analyzed. Median age at diagnosis was 57 years for both groups. For evaluable patients, the International Staging System at diagnosis was determined. The percentage of stage I, II and III patients in the African-American group was 53%, 28% and 19% respectively. The percentage of stage I, II and III patients in the Caucasian group was 40%, 30% and 29% respectively. These staging data were not significantly different between racial groups. In both groups, 89% of patients received a novel therapeutic (thalidomide, lenalidomide or bortezomib) during their treatment course. We found a statistically significant difference in the percentage of African-American and Caucasian patients who received high dose chemotherapy and ASCT (65% and 76%, respectively, p=0.04). There was no difference observed in the number of second transplants performed in the two groups (19 in both groups). Response to therapy is detailed in Table 1. There was no difference in overall response to any therapy of evaluable patients between the two groups. With a median follow-up time of 35 months, the median overall survival from diagnosis has not been reached in either group. Kaplan-Meir analysis shows that there is no difference in overall survival between black and white patients (p =0.1) Conclusions: In this single-center, retrospective study of multiple myeloma patients treated predominately with novel agents, with or without ASCT, no survival difference was observed between African-American and Caucasian patients. To our knowledge, this is the largest number of African-American myeloma patients analyzed for survival in a single-center study. Recognizing the potential disparities in healthcare access, this may not represent outcomes for all African-American patients with myeloma. Since median overall survival has not been reached in this data, it is possible that survival differences will become apparent in the future, and further follow-up is needed. However, this review suggests that in the era of novel therapeutics and ASCT resulting in improved overall response rates, survival in African-American patients may be equivalent to Caucasian patients. Further efforts are needed to enroll African-American patients on clinical trials to validate this observation prospectively. Disclosures: No relevant conflicts of interest to declare.

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Galliano, Emmanuel, and Danielle Alloin. "Gas trapping in extremely massive clusters in NGC 1365." Proceedings of the International Astronomical Union 5, S266 (August 2009): 399. http://dx.doi.org/10.1017/s1743921309991475.

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AbstractThree radio cm sources in the central star-forming kpc of the closeby barred Seyfert galaxy NGC 1365 are observed. The complete dataset includes VLT infrared J, K, L and N images and spectra. The main observed features include (i) a rising dust continuum towards the mid-infrared (MIR), (ii) bright H emission lines and PAH (polycyclic aromatic hydrocarbon) features, (iii) a bright MIR [Neii] line, and (iv) no detection of MIR [Siv] or [Ariii] lines. For a typical cluster star-formation history and initial mass function, the [Ariii]/[Neii] and [Siv]/[Neii] ratios exhibit an abrupt decrease of several orders of magnitude at an age of ~ 7 Myr. The nondetection of [Ariii] and [Siv] indicates that the clusters are of approximately this age.

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Nelson, C. J., S. Krishna Prasad, and M. Mathioudakis. "Evolution of supersonic downflows in a sunspot." Astronomy & Astrophysics 636 (April 2020): A35. http://dx.doi.org/10.1051/0004-6361/201937357.

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Context. Supersonic downflows have been observed in transition region spectra above numerous sunspots, however, little research has been conducted to date into how persistent these signatures are within sunspots on timescales longer than a few hours. Aims. We aim to analyse the lead sunspot of AR 12526 to infer the properties and evolution of supersonic downflows occurring within it using high-spatial and spectral resolution data. Methods. We analysed 16 large, dense raster scans sampled by the Interface Region Imaging Spectrograph. These rasters tracked the lead sunspot of AR 12526 across the solar disc at discrete times between 27 March 2016 and 2 April 2016, providing spectral profiles from the Si IV, O IV, Mg II, and C II lines. Additionally, we studied one sit-and-stare observation acquired on 1 April 2016 centred on the sunspot to analyse the evolution of supersonic downflows on shorter timescales. Results. Supersonic downflows are variable within this sunspot both in terms of spatial structuring and velocities. Thirteen of the 16 raster scans display some evidence of supersonic downflows in the Si IV 1394 Å line co-spatial to a sustained bright structure detected in the 1400 Å slit-jaw imaging channel; a peak velocity of 112 km s−1 is recorded on 29 March 2016. Evidence for supersonic downflows in the O IV 1401 Å line is found in 14 of these rasters; the spatial structuring in this line often differs from that inferred from the Si IV 1394 Å line. Only one example of a supersonic downflow is detected in the C II 1335 Å line and no downflows are found in the Mg II 2796 Å lines at these locations. In the sit-and-stare observations, no dual flow is initially detected, however, a supersonic downflow develops after approximately 60 min. This downflow accelerates from 73 km s−1 to close to 80 km s−1 in both the Si IV 1394 Å and O IV 1401 Å lines over the course of 20 min before the end of the observation. Conclusions. Supersonic downflows are found in the Si IV 1394 Å line in 13 of the 16 rasters studied in this work. The morphology of these downflows evolved over the course of both hours and days and was often different in the Si IV 1394 Å and O IV 1401 Å lines. These events were found co-spatial to a bright region in the core of the Si IV 1394 Å line, which appeared to form at the footpoints of coronal fan loops. Our results indicate that one raster is not enough to conclusively draw inferences about the properties of supersonic downflows within a sunspot during its lifetime.

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Banerjee, S., B. Manna, and J. T. Shahu. "Numerical assessment of geocell-reinforced pavement performance subjected to cyclic loading conditions." IOP Conference Series: Earth and Environmental Science 1335, no. 1 (May 1, 2024): 012009. http://dx.doi.org/10.1088/1755-1315/1335/1/012009.

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Abstract A numerical analysis was conducted using PLAXIS 3D software on a geocell-reinforced pavement over a soft subgrade under cyclic loading conditions. This study illustrates surface deformation and vertical stress within the subgrade layer of a reinforced pavement. The accuracy of the FE model was confirmed by comparing the results ofthe present study with those reported in the literature. This study investigated the influence of various factors, such as different infill and subgrade materials inreinforced pavements, on the overall pavement performance. These findings were compared with those observed for conventional planar-reinforced pavements. For improved infill and subgrade materials, the total surface deformation of the reinforced section decreased by approximately 15%–40%. Compared with the improvement in subgrade properties, a significant reduction of approximately 10% was observed inthe pressure response at the subbase-subgrade interface when using improved infill material. Moreover, compared to the planar-reinforced pavement, the geocell-reinforcedpavement reduced vertical stress at the interface between the base and subgrade by approximately 26%.

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Martí i Arau, Albert. "Fiscalitat municipal sobre productes alimentaris a Castelló d’Empúries (1350–1365)." Mot so razo 19 (September 3, 2021): 51. http://dx.doi.org/10.33115/udg_bib/msr.v19i0.22665.

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During the 14th century, Catalan towns, together with those in the rest of the Crown of Aragon, issued enormous quantities of long-term debt, which took the form of sales of perpetual and lifelong annuities ("censals morts" and "violaris"), in order to finance their numerous economic needs of different types. As a consequence of the growing issuing of debt instruments, town governments had to build a fiscal system of increasing complexity to satisfy the rising annual interests. The system was based on a set of indirect taxes over commerce and the consumption of certain food and manufactured products. Castelló d’Empúries was not an exception and the town engaged and consolidated long-term debt between approximately 1350 and 1375. This article analyses the evolution of the taxes on food that the town government of Castelló was administering during this period (yield, tariffs and exempt groups), applied on wine and grapes, meat, cereal milling, bread, oil, fish and pigs. On these grounds, the article assesses whether the increasing town debt resulted in a growing tax pressure on its inhabitants, and offers an overview of the main food types that were commercialised in Castelló during the 14th century.

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Kushnareva, I. G., M. A. Makarov, A. E. Karateev, and A. I. Gorelova. "Trends in large joint total arthroplasty in patients with rheumatic diseases: an experience of a specialized department of traumatology and orthopedics." Modern Rheumatology Journal 17, no. 6 (December 19, 2023): 79–83. http://dx.doi.org/10.14412/1996-7012-2023-6-79-83.

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Total knee and hip arthroplasty (TKA and THA respectively) is frequently used in severe structural changes in patients with osteoarthritis (OA) and rheumatoid arthritis (RA).Objective: to evaluate the dynamics of the number of TKA of THA in patients with OA and RA treated in the Department of Traumatology and Orthopedics of V.A. Nasonova Research Institute of Rheumatology.Material and methods. The analysis of 11-year period (from 2012 to 2022) of surgical activity of the Department of Traumatology and Orthopedics of V.A. Nasonova Research Institute of Rheumatology.Results and discussion. Within the mentioned period, 2955 TKA and THA were performed in 1590 patients with OA and 1365 with RA. From 2012 to 2018, the number of surgeries in patients with OA and RA was approximately the same, but since 2019 there has been a significant increase in the number of total arthroplasties (TA) in OA. The median delta (Δ) of the number of TKA and THA performed annually over 11 years was 13.5 [-17.5; 75.7] in patients with OA and 2.5 [-10.25; 25.0] in patients with RA (p=0.032).Conclusion. In the last 11 years there was no significant dynamics in the number of TKA and THA in patients with RA. At the same time, there is a statistically significant increase in the number of TA in patients with OA, which is in line with the global trend.

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Yaskevich, Sergey, Anton A. Duchkov, and Yuriy Ivanov. "Approximate traveltime inversion in downhole microseismic monitoring." Geophysical Prospecting 68, no. 3 (December 10, 2019): 918–25. http://dx.doi.org/10.1111/1365-2478.12906.

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Papatzacos, Paul. "Approximate Partial-Penetration Pseudoskin for Infinite- Conductivity Wells." SPE Reservoir Engineering 2, no. 02 (May 1, 1987): 227–34. http://dx.doi.org/10.2118/13956-pa.

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Ghatak, Himadri Roy. "Reduction of Organic Pollutants with Recovery of Value-Added Products From Soda Black Liquor of Agricultural Residues by Electrolysis." July 2009 8, no. 7 (August 1, 2009): 4–10. http://dx.doi.org/10.32964/tj8.7.4.

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Batch electrolysis experiments were carried out on soda black liquors from agricultural residues at different interelectrode potentials. At low potential, the process was slow but energy-efficient, providing partial COD removal. It produced lignin at the anode with the exclusion of oxygen evolution. Hydrogen was produced at the cathode as a value-added product. At high interelectrode potential, the nascent oxygen produced at the anode led to oxidation of the organics. With prolonged electrolysis, complete removal of COD was possible, with a solution of sodium carbonate remaining. Low-potential electrolysis required about 2000 J of electricity per gram of COD removed, producing 180–190 mL hydrogen and approximately 0.55 g lignin. Electricity requirement per gram of COD removed in high-potential electrolysis varied from approximately 17,700 J at 1.5 V to approximately 149,000 J at 12 V. Approximately 1365 mL of hydrogen was produced for every gram of COD removed.

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Knežević, Mikonja, and Milesa Stefanović-Banović. "The Date of the Treatise ‘Contra Beccum’ of Gregory Palamas Revisited." Philotheos 21, no. 2 (2021): 201–11. http://dx.doi.org/10.5840/philotheos202121211.

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In this paper we try to give some further evidence concerning the chronology of Palamas’ treatise Contra Beccum. Taking into consideration different parameters, external and internal, we incline to think that this treatise was composed – or, at least, reworked – in 1355, approximately at the same period when Palamas published the second edition of his Logoi apodeiktikoi.

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Bisnovatyi-Kogan, G. S., and O. Y. Tsupko. "Approximate dynamics of dark matter ellipsoids." Monthly Notices of the Royal Astronomical Society 364, no. 3 (December 11, 2005): 833–42. http://dx.doi.org/10.1111/j.1365-2966.2005.09614.x.

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Hu, Wei-Kai, Chih Hung Wu, and Chang Hong Lin. "Economic approximate-K color printing algorithm." Multimedia Tools and Applications 72, no. 1 (January 6, 2013): 151–66. http://dx.doi.org/10.1007/s11042-012-1345-0.

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Takenouchi, T., F. Tabata, Y. Iwata, H. Hanzawa, M. Sugawara, and S. Ohya. "Hydrophilicity of quinolones is not an exclusive factor for decreased activity in efflux-mediated resistant mutants of Staphylococcus aureus." Antimicrobial Agents and Chemotherapy 40, no. 8 (August 1996): 1835–42. http://dx.doi.org/10.1128/aac.40.8.1835.

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The elevated expression of the norA gene is responsible for efflux-mediated resistance to quinolones in Staphylococcus aureus (E.Y.W. Ng, M. Trucksis, and D.C. Hooper, Antimicrob. Agents Chemother. 38:1345-1355, 1994). For S. aureus transformed with a plasmid containing the cloned norA gene, SA113(pTUS20) (H. Yoshida, M. Bogaki, S. Nakamura, K. Ubukata, and M. Konno, J. Bacteriol. 172:6942-6949, 1990), and an overexpressed mutant, SA-1199B (G.W. Kaatz, S.M. Seo, and C.A. Ruble, J. Infect. Dis. 163:1080-1086, 1991), the MICs of norfloxacin increased 16 and 64 times compared with its MICs for the recipient and wild-type strains, SA113 and SA-1199, respectively. MICs of CS-940, however, increased only two and eight times, even though these two fluoroquinolones are similarly hydrophilic (apparent logPs of approximately -1). No good correlation was found, among 15 developed and developing quinolones, between the increment ratio in MICs and hydrophobicity (r = 0.61). Analysis of the quantitative structure-activity relationship among 40 fluoroquinolones revealed that the MIC increment ratio was significantly correlated with the bulkiness of the C-7 substituent and bulkiness and hydrophobicity of the C-8 substituent of fluoroquinolones (r = 0.87) and not with its molecular hydrophobicity (r = 0.47). Cellular accumulation of norfloxacin in SA-1199B was significantly lower than that in SA-1199, and it was increased by addition of carbonyl cyanide m-chlorophenyl hydrazone. On the other hand, accumulations of CS-940 in these strains were nearly identical, and they were not affected by addition of the protonophore.

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Hafsteinsdóttir, Thóra B., Machteld Mosselman, Coby Schoneveld, Yvette D. Riedstra, and Cas LJJ Kruitwagen. "Malnutrition in hospitalised neurological patients approximately doubles in 10 days of hospitalisation." Journal of Clinical Nursing 19, no. 5-6 (March 2010): 639–48. http://dx.doi.org/10.1111/j.1365-2702.2009.03142.x.

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Zhang, J., Sh Zhang, J. Liang, B. Tian, Z. Hou, and B. Zh Liu. "Photovoltaic Generation Data Cleaning Method Based on Approximately Periodic Time Series." IOP Conference Series: Earth and Environmental Science 63 (May 2017): 012008. http://dx.doi.org/10.1088/1755-1315/63/1/012008.

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Bostock, M. G. "Kirchhoff-approximate inversion of teleseismic wavefields." Geophysical Journal International 149, no. 3 (May 26, 2002): 787–95. http://dx.doi.org/10.1046/j.1365-246x.2002.01687.x.

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HAWKES, P. W., B. LENCOVÁ, and M. LENC. "Approximate expressions for electron lens properties*." Journal of Microscopy 179, no. 2 (August 1995): 145–57. http://dx.doi.org/10.1111/j.1365-2818.1995.tb03626.x.

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Koldoba, A. V., O. A. Kuznetsov, and G. V. Ustyugova. "An approximate Riemann solver for relativistic magnetohydrodynamics." Monthly Notices of the Royal Astronomical Society 333, no. 4 (July 2002): 932–42. http://dx.doi.org/10.1046/j.1365-8711.2002.05474.x.

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Atwell, Williams S. "A Seventeenth-Century ‘General Crisis’ in East Asia?" Modern Asian Studies 24, no. 4 (October 1990): 661–82. http://dx.doi.org/10.1017/s0026749x00010532.

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Approximately ten years ago now, several colleagues and I were discussing Geoffrey Parker and Lesley Smith's then recently-published volume on the ‘Seventeenth-Century Crisis’ when a specialist in Byzantine history told us that in his opinion at least, Parker, Smith, and the others who had contributed to their jointly-edited work had gotten it all wrong. The reallyimportant‘general crisis’ in pre-modern times, he believed, had occurred not in the seventeenth century but rather in the fourteenth. As he went on to discuss the impact of climatic change, food shortages, epidemic disease, monetary fluctuations, and military operations on fourteenth-century Europe and the Middle East, I began to think about some of the great and terrible events that had occurred in East Asian history during that same century: the fall of the Kamakura Shogunate (1185–1330S) and the political turmoil of the Northern and Southern Dynasties (Nambokuchō) period (1336–92) in Japan; the economic and military disasters surrounding the fall of the Mongol Yuan dynasty (1279–1368) in China; and the food shortages, ‘Japanese pirate’ (wakō) raids, and civil wars that paved the way for the founding of the Yi dynasty (1392–1910) in Korea. In subsequent readings I added economic and political strife in fourteenth-century Southeast Asia, the decline of the Delhi Sultanate in India, the collapse of the Ilkhanate (1256–1335) in Persia, and the destructive rise of Timur (1336–1405) in Transoxania. Surely a case could be made, I came to think, for a 'General Crisis of the Fourteenth Century,' one much broader in scope than even our Byzantine specialist had been considering.

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Christensen, Niels B. "Fast approximate 1D modelling and inversion of transient electromagnetic data." Geophysical Prospecting 64, no. 6 (May 13, 2016): 1620–31. http://dx.doi.org/10.1111/1365-2478.12373.

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32

Reed, Michael L., Amanda Hamic, Charles L. Caperton, and Douglas J. Thompson. "Live birth after anonymous donation of twice-cryopreserved embryos that had been stored in liquid nitrogen for a cumulative storage time of approximately 13.5 years." Fertility and Sterility 94, no. 7 (December 2010): 2771.e1–2771.e3. http://dx.doi.org/10.1016/j.fertnstert.2010.04.071.

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33

Pries, A. R., D. Schonfeld, P. Gaehtgens, M. F. Kiani, and G. R. Cokelet. "Diameter variability and microvascular flow resistance." American Journal of Physiology-Heart and Circulatory Physiology 272, no. 6 (June 1, 1997): H2716—H2725. http://dx.doi.org/10.1152/ajpheart.1997.272.6.h2716.

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Microvessels are known to exhibit irregular shapes, deviating substantially from an idealized cylindrical tube geometry. Such irregularities must be taken into account in calculating microvascular flow resistance and may add to the observation that flow resistance in living microvessels in vivo is about twice that predicted on the basis of tube flow studies in vitro. The present study was aimed at providing a comprehensive database describing the apparent diameter variability for all segments of a complete microvascular network in the rat mesentery and assessing the impact of this variability on segmental flow resistance and the pressure drop across the network. Diameters were estimated by intravital microscopy at axial intervals of 20 microns along the 546 vessel segments of a mesenteric microvessel network, resulting in 6,319 separate diameter measurements. The amplitude of diameter variations in individual vessel segments decreased from approximately 15% of the mean vessel diameter in the smallest segments (approximately 5 microns diam) to approximately 5% in the largest segments (approximately 60 microns diam). Segmental hindrance was estimated to be 10-23% higher than calculated from arithmetic mean diameter, depending on the model used to estimate the hydrodynamically effective segment diameter. The overall pressure drop across the network calculated using a mathematical flow simulation was increased by 7-13.5%. This increase in flow resistance can explain approximately 10% of the observed discrepancy between flow resistance in vivo and in vitro.

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Alecian, G., and F. LeBlanc. "New approximate formulae for radiative accelerations in stars." Monthly Notices of the Royal Astronomical Society 332, no. 4 (June 1, 2002): 891–900. http://dx.doi.org/10.1046/j.1365-8711.2002.05352.x.

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35

Kipping, David M. "Investigations of approximate expressions for the transit duration." Monthly Notices of the Royal Astronomical Society 407, no. 1 (June 29, 2010): 301–13. http://dx.doi.org/10.1111/j.1365-2966.2010.16894.x.

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36

Ueno, Naoto T., Jie Gao, Liming Liu, Rong Shi, Shengxue Liu, Lili Tang, Peizhen Miao, Yang Qiu, Wei Gu, and Cheng Ying. "Abstract CT248: First in human trial of DB1305 in patients with advanced malignant solid tumors." Cancer Research 83, no. 8_Supplement (April 14, 2023): CT248. http://dx.doi.org/10.1158/1538-7445.am2023-ct248.

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Abstract Background: Trophoblast cell-surface antigen 2 (Trop-2) is known as tumor-associated calcium signal transducer 2 (TACSTD2) and plays a role in tumor progression, given its active interplay with several key molecular pathways associated with cancer development and progression. DB-1305 is a Trop-2 antibody-drug conjugate (ADC) composed of a humanized anti-Trop-2 immunoglobulin G1 (IgG1) monoclonal antibody, covalently linked to a proprietary DNA topoisomerase I inhibitor P1021 via a cleavable linker containing maleimide tetrapeptide, with a drug-to-antibody ratio (DAR) of approximately 4. Preclinical in vivo models show that DB-1305 demonstrates robust anti-tumor activity in Trop-2-high triple-negative breast cancer (TNBC), Trop-2-low small cell lung cancer (SCLC) and Trop-2-medium colon cancer but not Trop-2-negative SCLC, demonstrating the dependence of Trop-2 expression for the tumor-suppression activity of DB-1305 and appropriate safety profile supports the intended clinical use. This study aims to evaluate DB-1305 in terms of tolerability and preliminary anti-tumor activity in patients with advanced solid tumors. Methods: This is an open-label, multicenter, multiple-dose, Phase 1/2a study (NCT05438329), including dose escalation Phase 1 and dose-expansion Phase 2a in patients with pretreated advanced solid tumors. Patients should have histologically documented progressed/refractory disease on or after standard systemic anticancer treatments with proven benefits for their disease or without available standard treatments; adequate performance score (ECOG 0-1); adequate organ function and measurable disease as per RECIST v1.1 while without uncontrolled metastatic central nervous system (CNS) involvement and history of interstitial lung diseases. The dose escalation part will evaluate approximately five ascending dose levels of DB-1305 with accelerated titration for the first dose level followed by a “3+3” design for subsequent dose levels to identify the optimal dose, which will enroll up to 70 patients from the United States and China. Upon determining the optimal dose, seven tumor cohorts of 10-40 patients will be included in the dose expansion part, including non-small cell lung cancer, SCLC, hormone receptor-positive breast cancer, and TNBC. DB-1305 will be dosed in both parts until disease progression, clinical deterioration, withdrawal of consent, or unacceptable toxicity. The primary objectives are evaluating safety tolerability and identifying the optimal dose from Phase 1; assessing safety, tolerability, and objective response rate per RECIST v1.1 from Phase 2a. Secondary objectives include the assessment of the pharmacokinetics and immunogenicity of DB-1305. Exploratory objectives include the assessment of pharmacodynamic biomarkers and Exposure-Response correlation. As of 19 Dec 2022, 20 patients have been enrolled in the dose escalation part. Citation Format: Naoto T. Ueno, Jie Gao, Liming Liu, Rong Shi, Shengxue Liu, Lili Tang, Peizhen Miao, Yang Qiu, Wei Gu, Cheng Ying. First in human trial of DB1305 in patients with advanced malignant solid tumors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT248.

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Mancia, M. S., and Aurora Mancia. "Earth As Wealth Resource In The Crisul Repede Basin." Journal of Applied Engineering Sciences 5, no. 2 (December 1, 2015): 51–57. http://dx.doi.org/10.1515/jaes-2015-0021.

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Abstract From the entire globe surface which is over 13.5 billion ha, the agricultural area represents more than one quarter (means 3.4 billion ha). The cultivated areas cover approximately 1.5 billion ha, which means 8% of the total lands, to each inhabitant of the planet assuming the 0.25 ha. The most agricultural space is located in the temperate zone (about 2 billion ha), which represents 55% of agricultural space world and also here lies mostly in the sown area of the planet (830 thousand ha, 59%).

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Baxendale, F. P., R. C. Shearman, and L. A. Wit. "Annual White Grub Control in Kentucky Bluegrass, 1987." Insecticide and Acaricide Tests 13, no. 1 (January 1, 1988): 330a. http://dx.doi.org/10.1093/iat/13.1.330a.

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Abstract Nine insecticides were applied to 5- × 10-ft plots on a golf course in Lincoln, Nebr. (Lancaster County), on 5 Aug. Granular formulations were combined with 13.5 oz Milorganite, which served as a carrier, and were hand shaken over plots. Liquid formulations were applied with a C02 sprayer using an LF-4 nozzle at 28 psi and a spray rate of 4 gal/1000 sq ft spray rate. To ensure uniformity among plots, 13.5 oz of Milorganite were also applied over plots receiving liquid formulations and over untreated checks. The experiment was replicated 4 times using a randomized complete block design. Immediately following insecticide applications, the test area was irrigated with approximately 0.75 inches of water. An additional 3.75 inches of rainfall occurred during the posttreatment period. Product efficacy was evaluated 14 days after application (19 Aug) by removing 2 sections of sod, 1-sq-ft × 4 inches deep, from each plot and counting the number of surviving grubs.

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Miyamoto, Katsuhiko, Tomohito Yamasaki, Shota Tsuji, Kazuma Inoue, Godeung Park, Hirohisa Uchida, Akira Matsuura, Peter Krüger, and Takashige Omatsu. "Ultrawideband and High-Resolution Terahertz Spectroscopy: Structural Identification of Glucose." Photonics 9, no. 9 (August 25, 2022): 602. http://dx.doi.org/10.3390/photonics9090602.

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We report on the development of an ultrawideband and high-resolution THz spectroscopic system, which operates over a frequency range of 2–13.5 THz. This work goes beyond conventional THz spectroscopic measurements and demonstrates the capacity to differentiate D- and L-glucoses, which have the same molecular conformation and crystal structure. Furthermore, this system facilitates the structural identification of glucose microcrystals, which exists in α- and β-forms, revealing that L-glucose microcrystals are formed of a mixture of α- and β-D-glucose with approximately equal weight.

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Le, Hieu Giang, Shyh Chour Huang, Van Son Nguyen, and Thanh Phong Dao. "Reinforcement of Polypropylene Using Micro-Fillers." Applied Mechanics and Materials 300-301 (February 2013): 1321–24. http://dx.doi.org/10.4028/www.scientific.net/amm.300-301.1321.

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This paper focuses on the effect the ratio of filler (Na10MB3A) on the tensile strength of polypropylene (PP). This filler has been added to PP in various ratios and mixed evenly before injecting. The tensile strength of PP increases gradually when the ratio of filler increases. Tensile strength reaches its maximum value with a certain ratio of filler, and thereafter the strength decreases as the ratio of fillers is increased. This research revealed that the tensile strength of PP can rise by approximately 13.5% with the addition of Na10MB3A at a ratio of 3%.

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da Silva Cunei, Jeannette M. A., Christopher J. Murphy, Spencer S. Jang, and Roy W. Bellhorn. "Nutritionally variant streptococci associated with corneal ulcers in horses: 35 cases (1982-1988)." Journal of the American Veterinary Medical Association 197, no. 5 (September 1, 1990): 624–26. http://dx.doi.org/10.2460/javma.1990.197.05.624.

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Summary Nutritionally variant streptococci (nvs) are nutritionally deficient viridans streptococci that require pyridoxal for growth. Although nvs are pathogenic in human beings, they have not been considered to be pathogenic in domestic animals. In 1982 and 1983, 24 isolates of nvs were recovered from horses with ulcerative keratitis. A retrospective study was done to determine the incidence of nvs in horses with corneal disease. The medical records of 249 horses (259 eyes) examined for clinical signs of corneal disease were reviewed. Nutritionally variant streptococci were isolated from approximately 13.5% of horses with ulcerative keratitis.

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42

Li, Yaoguo, and Douglas W. Oldenburg. "Approximate inverse mappings in DC resistivity problems." Geophysical Journal International 109, no. 2 (May 1992): 343–62. http://dx.doi.org/10.1111/j.1365-246x.1992.tb00101.x.

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Farquharson, C. G., and D. W. Oldenburg. "Approximate sensitivities for the electromagnetic inverse problem." Geophysical Journal International 126, no. 1 (July 1996): 235–52. http://dx.doi.org/10.1111/j.1365-246x.1996.tb05282.x.

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Kipping, David M. "Erratum: Investigations of approximate expressions for the transit duration." Monthly Notices of the Royal Astronomical Society 408, no. 3 (September 30, 2010): 1968. http://dx.doi.org/10.1111/j.1365-2966.2010.17111.x.

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45

STOREY, R. M., H. K. DAVIS, D. OWEN, and L. MOORE. "Rapid approximate estimation of volatile amines in fish*." International Journal of Food Science & Technology 19, no. 1 (June 28, 2007): 1–10. http://dx.doi.org/10.1111/j.1365-2621.1984.tb00321.x.

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46

Plachý, Jan, Viktorie Weiss, and Ladislav Bartuška. "Problems with Approximate Bearing Capacity of Gravel Soils." IOP Conference Series: Earth and Environmental Science 44 (October 2016): 022022. http://dx.doi.org/10.1088/1755-1315/44/2/022022.

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47

Cabral-Prieto, A., M. Jimenez-Dominguez, and M. Torres-Valderrama. "An approximate method to deconvolute simulated Mössbauer spectra." International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 38, no. 2 (January 1991): 261. http://dx.doi.org/10.1016/1359-0197(91)90270-c.

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48

Rowe, Ellen W., Timothy W. Curby, and Helyn Kim. "Variance in Teacher Ratings of Children’s Adjustment." Journal of Psychoeducational Assessment 37, no. 1 (September 15, 2017): 26–39. http://dx.doi.org/10.1177/0734282917728235.

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This study examined the variance in teacher ratings attributable to teacher, occasion, and child on the original Behavior Assessment System for Children (BASC). Teachers rated approximately 1,100 girls (52%) and boys (48%) at four public elementary schools over 3 years. About half of the students were rated twice and about a seventh 3 times. Approximately 30% of students were White, 50% African American, 9% Hispanic, 2% multiracial, and 2% Asian. Children were in kindergarten to fifth grade. Cross-classified random effects models were used to account for multiple occasions of data nested within both children and teachers. Overall, the child accounted for the largest amount of variance in ratings (52.3%) followed by occasion (34.2%) and teacher (13.5%). However, large differences existed across composites and scales. The findings suggest that teachers’ ratings of adaptive competencies, externalizing behaviors, and school problems are based primarily on child behavior/characteristics. Ratings of internalizing problems may be more situational.

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Mor, Gopal K., Maria A. Carvalho, Ooman K. Varghese, Michael V. Pishko, and Craig A. Grimes. "A room-temperature TiO2-nanotube hydrogen sensor able to self-clean photoactively from environmental contamination." Journal of Materials Research 19, no. 2 (February 2004): 628–34. http://dx.doi.org/10.1557/jmr.2004.19.2.628.

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Described is a room-temperature hydrogen sensor comprised of a TiO2-nanotube array able to recover substantially from sensor poisoning through ultraviolet (UV) photocatalytic oxidation of the contaminating agent; in this case, various grades of motor oil. The TiO2 nanotubes comprising the sensor are a mixture of both anatase and rutile phases, having nominal dimensions of 22-nm inner diameter, 13.5-nm wall thickness, and 400-nm length, coated with a 10-nm-thick noncontinuous palladium layer. At 24 °C, in response to 1000 ppm of hydrogen, the sensors show a fully reversible change in electrical resistance of approximately 175,000%. Cyclic voltammograms using a 1 N KOH electrolyte under 170 mW/cm2 UV illumination show, for both a clean and an oil-contaminated sensor, anodic current densities of approximately 28 mA/cm2 at 2.5 V. The open circuit oxidation potential shows a shift from 0.5 V to −0.97 V upon UV illumination.

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Gallup, Jack M., Randy E. Sacco, Fatoumata B. Sow, and Mark R. Ackermann. "Laser Capture Microdissection Revisited as a Tool for Transcriptomic Analysis: Application of an Excel-Based qPCR Preparation Software (PREXCEL-Q)." International Journal of Biomedical Science 5, no. 2 (June 15, 2009): 105–24. http://dx.doi.org/10.59566/ijbs.2009.5105.

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The ability to reliably analyze cellular and molecular profiles of normal or diseased tissues is frequently complicated by the inherent heterogeneous nature of tissues. Laser Capture Microdissection (LCM) is an innovative technique that allows the isolation and enrichment of pure subpopulations of cells from tissues under direct microscopic examination. Material obtained by LCM can be used for downstream assays including gene microarrays, western blotting, cDNA library generation and DNA genotyping. We describe a series of LCM protocols for cell collection, RNA extraction and qPCR gene expression analysis. Using reagents we helped develop commercially, we focus on two LCM approaches: laser cutting and laser capture. Reagent calculations have been pre-determined for 10 samples using the new PREXCEL-Q assay development and project management software. One can expect the entire procedure for laser cutting coupled to qPCR to take approximately 12.5-15 h, and laser capture coupled to qPCR to take approximately 13.5-17.5 h.

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