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Dissertations / Theses on the topic 'APPswe mice'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Papadopoulos, Panayiota. "Mice co-expressing human APPSwe/Ind TGF-B1 as a tool for the identification of Alzheimer's disease therapies." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110363.

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Elevated brain levels of amyloid-β (Aβ) and transforming growth factor- β1 (TGF-β1) are thought to contribute to the cognitive and cerebrovascular alterations of Alzheimer's disease (AD). Here, we sought to investigate the role of simultaneous increases of Aβ and TGF-β1 on cerebrovascular, neuronal, glial and mnemonic function using a bitransgenic mouse model concurrently overexpressing a mutated form of the human amyloid precursor protein (APPSwe,Ind) and a constitutively active form of TGF-β1 (A/T mice). In addition, we attempted to counter these deficits using three different pharmacologica

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2

Ahmad, Shakeel. "The impact of pesticides on apple mite communities." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3422565.

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Laboratory, field and semi-field experiments have been carried out on the predatory mites Kampimodromus aberrans, Amblyseius andersoni, Typhlodromus pyri and Phytoseius finitimus in order to optimize biological control strategies against phytophagous mites in apple orchards. The first experiment concerned the augmentative releases of K. aberrans in organic and conventional apple orchards. The most frequent insecticides used in organic orchards were pyrethrins and spinosad, whereas neonicotinoids, OPs and IGRs were used in conventional orchards. K. aberrans releases were successful and predator

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3

Mobley, Kendrick Norman. "Gas exchange characteristics of apple and peach leaves as influenced by European red mite and twospotted spider mite." Thesis, Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/52089.

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Three densities of European red mite (ERM) (<i>Panonychus ulmi</i> Koch) and twospotted spider mite (TSM) (<i>Tetranychus urticae</i> (Koch)) were maintained on greenhouse-grown 'Imperial Delicious' apple (<i>Malus domestica</i>) and 'Redhaven' peach (<i>Prunus persica</i>) leaves. As ERM- and TSM-days increased, apple leaf net photosynthesis (Pn), transpiration (Tr) , and chlorophyll content (TCHL) decreased linearly. TSM was more damaging to apple leaf gas exchange than ERM. Apple water use efficiency (WUE) declined similarly with increasing mite-days for both mite species. Apple specific le

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4

Villanueva, Ra Raúl Timoteo. "Ecology of the mite complex on apple and related pest management implications." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20708.pdf.

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5

Cuthbertson, Andrew Garnet Steen. "The role of the predatory mite Anystis baccarum in Bramley apple orchards." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326402.

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6

Rogers, Richard E. L. "Insect and mite monitoring in commercial apple orchards in Nova Scotia (1979-1985)." Thesis, McGill University, 1986. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=65368.

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7

Ogura, Kasane. "Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-inflammatory Cytokines Expression in Liver of Diabetic ob/ob Mice." Kyoto University, 2017. http://hdl.handle.net/2433/225979.

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8

Campbell, Richard John. "Effect of nitrogen fertilization on the physiological damage and subsequent recovery of mite-infested apple leaves /." This resource online, 1988. http://scholar.lib.vt.edu/theses/available/etd-04122010-083649/.

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9

Campbell, Richard J. "Effect of nitrogen fertilization on the physiological damage and subsequent recovery of mite-infested apple leaves." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/42042.

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Two experiments were conducted with field- and container-grown 'Delicious' apple trees to evaluate the effect of nitrogen fertilization on the physiology of apple leaves subjected to European red mite feeding, and the subsequent recovery of leaf function following mite removal. Nitrogen (N) fertilization affected the visual damage, and the photosynthetic response of 'Imperial Delicious' apple leaves to mite feeding. Visual damage occurred first, and remained greatest on the low N treatment throughout the experiment. High N trees exhibited a linear decline in Pn with increasing MD, in contras

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10

Fitzgerald, Jean D. "Resistance to organophosphorus insecticides in the predatory mite Typhlodromus pyri Scheuten (Acarina: Phytoseiidae), an important biocontrol agent in apple orchards." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298983.

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11

Hopkins, Ashley R. "Privacy Within Photo-Sharing and Gaming Applications: Motivation and Opportunity and the Decision to Download." Ohio University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1556821782704244.

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12

Hazara, Altaf Hussain. "Studies of the distribution of the European red spider mite, Panonychus ulmi (Koch) (Acarina: Tetranychidae) and the apple rust mite, Aculus schlechtendali (Nal) (Acarina: Euriophyidae) : in an experimental glasshouse and a commercial orchard." Thesis, University of Southampton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290365.

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13

Ermoshina, Kseniia. "Au code, citoyens : mise en technologies des problèmes publics." Thesis, Paris Sciences et Lettres (ComUE), 2016. http://www.theses.fr/2016PSLEM072/document.

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La thèse étudie les applications dites citoyennes pour mobiles et web qui sont développées en réponse aux problèmes publics variés et basées sur le principe de crowdsourcing. Elle s’intéresse à la fois à la conception de ces dispositifs, à leurs usages et aux façons dont ces outils transforment la communication des citoyens entre eux, et avec les pouvoirs publics. Elle explore les nouveaux formats d’innovation, comme les hackathons civiques, et interroge l’usage du code informatique en tant que nouvel instrument d’action collective.La thèse mobilise une méthodologie qui puise dans les répertoi

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14

Lee, Yi-Heng, and 李以恆. "The impact of high fat diet on energy metabolism in APPswe/PS1dE9 transgenic mice." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/ff5zv7.

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博士<br>國立陽明大學<br>跨領域神經科學國際研究生博士學位學程<br>107<br>Unbalanced diets such as calorie-rich high-fat and high-carbohydrate diets contribute to the development of metabolic syndrome. Previous studies also have demonstrated a positive correlation between metabolic syndrome and Alzheimer’s disease (AD). To study interaction between chronic high-fat diet and Alzheimer’s disease, we created a high-fat diet induced obese APP/PS1 transgenic mice to explore the impacts of HFD on energy metabolism in AD mice. HFD-induced obese APP/PS1 mice (HFD AD) mice were glucose intolerant as compared to wild-type littermat

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15

Coles, Madilyn. "Evaluation of the therapeutic potential of low dose chronic cannabidiol (CBD) treatment to reverse behavioural deficits of APPSwe/PS1ΔE9 transgenic female mice". Thesis, 2019. http://hdl.handle.net/1959.7/uws:57347.

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Introduction: Alzheimer’s disease (AD) is a neurodegenerative disease that causes behavioural and cognitive impairments and is hallmarked by amyloid plaques and neurofibrillary tangles of the protein tau. There is currently no cure for AD, with currently available treatments only targeting symptoms. Murine models of AD, such as the APPSwe/PS1ΔE9 (APPxPS1) model, replicate important aspects of the disease and allow preclinical insights into the efficacy of other potential therapeutics. With evidence that targeting the endocannabinoid system may be therapeutic in AD, cannabidiol (CBD) has been o

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