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1

Hartanti, Anastasia Tatik, Amelia Raharjo, and Agustin Wydia Gunawan. "Rhizopus Rotting on Agricultural Products in Jakarta." HAYATI Journal of Biosciences 27, no. 1 (January 1, 2020): 37. http://dx.doi.org/10.4308/hjb.27.1.37.

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Agricultural products may easily perish if they are not well taken care of during postharvest treatment. One of the main causes in damaged products is the biological contamination of pathogenic fungi, such as Rhizopus spp. that gives rise to Rhizopus rot symptoms. The purpose of this research was to isolate Rhizopus spp. from different agricultural products showing Rhizopus rot symptoms as well as to identify them. Rhizopus pure cultures were isolated on potato dextrose agar. Identification was done through molecular techniques using PhytopureTM DNA Extraction Kit and Maxwell® RSC Plant DNA Kit for DNA isolation, internal transcribed spacer (ITS4 and ITS5) as primers for amplification, and molecular evolutionary genetics analysis 7 (MEGA7) for the reconstruction of phylogenetic tree from sequence result. The phylogenetic tree using Maximum Likelihood statistics with 1,000 replications of bootstrap test showed five strains, namely AR9, AR10, AR11, AR13, and AR14, which belong to R. delemar, and the other seven remaining strains, AR1-AR7 belong to R. stolonifer. Identification was clarified with morphological and physiological data using Rhizopus growth at temperature control of 33 and 42°C as well as microscopic observation involving rhizoid, columella, measurement of sporangiospores, and sporangiophores.
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2

Ohike, Tatsuya, Tetsuya Matsukawa, Masahiro Okanami, Shin’ichiro Kajiyama, and Takashi Ano. "Biological Control Potential of Streptomyces sp. AR10 Producing Albocycline Isolated from Soil around Ant Nest." Journal of Agricultural Science 10, no. 3 (February 9, 2018): 54. http://dx.doi.org/10.5539/jas.v10n3p54.

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Fifty actinomycetes were isolated from fifteen soil samples and were screened for their antagonism against fungal plant pathogens by dual culture assay, and one of the strain named AR10 was shown to be most effective in suppression of growth of plant pathogen. An antifungal compound of AR10 was extracted, and purified by TLC and HPLC. As a result of NMR and LC-MS analysis, the antifungal compound was identified as albocycline. AR10 suppressed Rhizoctonia damping-off of cucumber in infection control assay. The 16S rDNA sequence of AR10 shows high sequence similarity to those of genus Streptomyces, and the closest similarity was found in the sequence of S. lanatus NBRC 12787T with 98.7% similarity. However, the production of albocycline in Streptomyces closely related to AR10 in the phylogenetic tree has not been reported. Our finding suggests that AR10 can be a candidate for biological control agents.
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3

Kaykioglu, Gul, and Elcin Gunes. "Comparison of Acid Red 114 Dye Adsorption by Fe3O4and Fe3O4Impregnated Rice Husk Ash." Journal of Nanomaterials 2016 (2016): 1–10. http://dx.doi.org/10.1155/2016/6304096.

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The removal of Acid Red 114 (AR114) dye by adsorption process, using the magnetic nanoparticle (RHA-MNP) which is produced from rice husk ash burned at 300°C and the magnetic nanoparticle (MNP, Fe3O4), was studied. Batch processes were used under different test parameters: pH (2, 4, 6, and 10) and without pH, initial dye concentration (20, 40, 60, 80, and 100 mg/L), and contact time (0, 1, 5, 10, 15, 30, 45, 60, 90, and 150 min). Optimum conditions for AR114 removal were found to be at natural pH (pH without correction) for both adsorbents. Freundlich isotherm was found to be more consistent for MNP and Langmuir isotherm was found to be more consistent for RHA-MNP. The maximum adsorption capacities of MNP and RHA-MNP adsorbents for AR114 dye were equal to 111 mg/g. The kinetic experimental data fitted the pseudo-second-order model for both MNP and RHA-MNP. It can be concluded that RHA-MNP which is a waste could be used as low-cost adsorbent to remove AR114 from aqueous solution.
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4

Teklu, Misghina G., Corrie H. Schomaker, Thomas H. Been, and Leendert P. G. Molendijk. "Tuber and root resistance of potato genotypes against Meloidogyne chitwoodi in the presence of Avena strigosa, related to tuber quality." Nematology 19, no. 3 (2017): 281–91. http://dx.doi.org/10.1163/15685411-00003047.

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Relative tuber infestation and quality of two Meloidogyne chitwoodi resistant potato genotypes, AR04-4096 and 2011M1, were compared in glasshouse experiments at initial population density () = 16 second-stage juveniles (g dry soil)−1 in the presence and absence of the bristle oat, Avena strigosa. When A. strigosa was added, ( final population) on both AR04-4096 and 2011M1 increased 130×, increased 1.9 and 3.7×, respectively, while × fresh root weight (FRW)−1 was the same. Nematode hatch from peel of AR04-4096, without A. strigosa, was delayed by 3 weeks but relative hatching rate was increased. Although the RStuber (RS = Relative Susceptibility) of both AR04-4096 and 2011M1 were lower than 1%, in the presence of A. strigosa tuber quality of 2011M1 dropped below the marketable level, while that of AR04-4096 was hardly affected. We conclude that: i) is influenced by root mass; ii) root quality influences nematode hatch; iii) tuber quality is not an estimator for tuber resistance, and the reverse; iv) root resistance is equal to tuber resistance.
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5

Fu, Yun-Chang, Hongshen Jiang, and Paul Bishop. "An Inhibition Study of the Effect of Azo Dyes on Bioactivity of Biofilms." Water Science and Technology 29, no. 7 (April 1, 1994): 365–72. http://dx.doi.org/10.2166/wst.1994.0363.

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An inhibition study showed that toxic compounds caused two responses when present at low concentration. One is stimulation of the biomass by simply serving as an energy source; this caused an increase in the total respiration rate. The other is inhibition of the reaction. AR14 was more toxic than AO7 for biofilm from reactors fed with a primary substrate. However, AO7 demonstrated inhibition for biofilm from reactors fed with AR14 and primary substrate, and AR14 could serve as a carbon source for the same film.
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6

Garg, Alok, Gaganpreet Kaur, Vikas K. Sangal, Pramod K. Bajpai, and Sushant Upadhyay. "Optimization methodology based on neural networks and box-behnken design applied to photocatalysis of acid red 114 dye." Environmental Engineering Research 25, no. 5 (October 22, 2019): 753–62. http://dx.doi.org/10.4491/eer.2019.246.

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The present work deals with the modeling and optimization of photocatalytic degradation (UV/TiO<sub>2</sub>) of aqueous solution of Acid Red 114 (AR114) dye using Artificial Neural Networks (ANN) and RSM. Photocatalytic treatment of AR114 has been executed using suspension TiO<sub>2</sub>catalyst for commercial applications exposed to ultraviolet irradiation in a shallow pond reactor. ANN optimization has been applied to for predicting the behavior of photocatalysis. The input parameters used for analysis of aqueous dye solution are - TiO<sub>2</sub> dose, pH of the dye solution, initial dye concentration, UV light intensity, time and area/volume, and time whereas the outputs are evaluated in form of degradation and decolorization efficiency of AR114. The outcomes of ANN optimization have been experimentally validated. Results achieved establish ANN modeling as a good predictive model. Parameteric optimization using multi-parameter optimization has been employed with desirability function approach. Results obtained from RSM are in line as per the results of ANN modeling as well as experimental. First order kinetics is use to effectively express degradation and decolorization of AR114 dyes. Total organic carbon (TOC) removal and GC-MS study of the dye shows the total mineralization and formation of non-toxic intermediate products.
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7

Sheppard, Ryan L., Espen E. Spangenburg, Eva R. Chin, and Stephen M. Roth. "Androgen receptor polyglutamine repeat length affects receptor activity and C2C12 cell development." Physiological Genomics 43, no. 20 (October 2011): 1135–43. http://dx.doi.org/10.1152/physiolgenomics.00049.2011.

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Testosterone (T) has an anabolic effect on skeletal muscle and is believed to exert its local effects via the androgen receptor (AR). The AR harbors a polymorphic stretch of glutamine repeats demonstrated to inversely affect receptor transcriptional activity in prostate and kidney cells. The effects of AR glutamine repeat length on skeletal muscle are unknown. In this study we examined the effect of AR CAG repeat length on AR function in C2C12 cells. AR expression vectors harboring 14, 24, and 33 CAG repeats were used to assess AR transcriptional activity. C2C12 cell proliferation, differentiation, gene expression, myotube formation, and myonuclear fusion index were assessed. Transcriptional activity increased with increasing repeat length and in response to testosterone (AR14 = 3.91 ± 0.26, AR24 = 25.21 ± 1.72, AR33 = 36.08 ± 3.22 relative light units; P < 0.001). Ligand activation was increased for AR33 (2.10 ± 0.04) compared with AR14 (1.54 ± 0.09) and AR24 (1.57 ± 0.05, P < 0.001). AR mRNA expression was elevated in each stably transfected line. AR33 cell proliferation (20,512.3 ± 1,024.0) was decreased vs. AR14 (27,604.17 ± 1,425.3; P < 0.001) after 72 h. Decreased CK activity in AR14 cells (54.9 ± 2.9 units/μg protein) in comparison to AR33 (70.8 ± 8.1) ( P < 0.05) was noted. The myonuclear fusion index was lower for AR14 (15.21 ± 3.24%) and AR33 (9.97 ± 3.14%) in comparison to WT (35.07 ± 5.60%, P < 0.001). AR14 and AR33 cells also displayed atypical myotube morphology. RT-PCR revealed genotype differences in myostatin and myogenin expression. We conclude that AR polyglutamine repeat length is directly associated with transcriptional activity and alters the growth and development of C2C12 cells. This polymorphism may contribute to the heritability of muscle mass in humans.
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8

Shojaat, Rahim, Afzal Karimi, Naghi Saadatjoo, and Soheil Aber. "Dye removal from artificial wastewater using heterogeneous bio-fenton system." Chemical Industry and Chemical Engineering Quarterly 23, no. 4 (2017): 447–56. http://dx.doi.org/10.2298/ciceq160621058s.

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In the present study, GOx/MnFe2O4/calcium alginate nano-composite was prepared by the trapping enzyme/nanoparticles in calcium alginate. The prepared absorbent was applied for decolorization of artificial dye wastewater of acid red 14 (AR14) by heterogeneous bio-Fenton system. Kinetic and isotherm studies were carried out. The decolorization of acid red 14 followed the Michaelis- Menten, pseudo-first order and pseudo-second order kinetic models. Good correlation coefficients were obtained by fitting the experimental data to Michaelis- Menten and pseudo-second order kinetic models. The adsorption isotherms were described by Langmuir, Freundlich and Temkin isotherms. Among the three isotherm models, the Freundlich model was fitted with the equilibrium data obtained from adsorption of AR14 onto MnFe2O4/calcium alginate; while Temkin isotherm gave the best correlation for adsorption on MnFe2O4 nanoparticles. The effect of various parameters such as initial pH of solution, initial dye concentration, and contact time on the adsorption of AR14 on MnFe2O4 and MnFe2O4/ /calcium alginate as well as dye enzymatic decomposition was studied. The decolorization of AR14 with initial concentration of 10 mg.L?1 by using GOx/ /MnFe2O4/calcium alginate was 60.17%.
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9

Chipps, Bradley E. "AR101 Oral Immunotherapy for Peanut Allergy." Pediatrics 144, Supplement 1 (December 2019): S31.1—S31. http://dx.doi.org/10.1542/peds.2019-2461uu.

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10

Kalmokoff, M. L., T. D. Cyr, M. A. Hefford, M. F. Whitford, and R. M. Teather. "Butyrivibriocin AR10, a new cyclic bacteriocin produced by the ruminal anaerobeButyrivibrio fibrisolvensAR10: characterization of the gene and peptide." Canadian Journal of Microbiology 49, no. 12 (December 1, 2003): 763–73. http://dx.doi.org/10.1139/w03-101.

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The gene (bviA) encoding the ruminal bacteriocin butyrivibriocin AR10 was cloned from an EcoRI library by using an oligonucleotide probe based on a partial peptide sequence of the previously isolated peptide. The gene encoded an 80 amino acid prebacteriocin that demonstrated significant identity with the cyclic bacteriocin gassericin A. Negative ion time of flight mass spectroscopic analysis (ESI/MS) indicated a mass of 5981.5 Da for the isolated bacteriocin, a molecular mass that could not be generated by removal of a leader peptide alone. However, an N- to C-terminal cyclization of the predicted mature bacteriocin resulted in a peptide that conformed to the determined mass and charge characteristics. Northern blotting confirmed that expression of bviA mirrored the production of the bacteriocin in both liquid and solid media.Key words: Butyrivibrio fibrisolvens AR10 rumen bacteriocin.
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11

MOCEK, T., C. M. KIM, H. J. SHIN, D. G. LEE, Y. H. CHA, K. H. HONG, and C. H. NAM. "Investigation of soft X-ray emission from Ar clusters heated by ultrashort laser pulses." Laser and Particle Beams 20, no. 1 (January 2002): 51–57. http://dx.doi.org/10.1017/s026303460220107x.

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We report soft X-ray spectra (4–18 nm) produced by the interaction of 25–100-fs laser pulses at an intensity of up to 7 × 1016 W/cm2 with a cryogenically cooled Ar gas jet. New spectral lines from Ar8+, Ar9+, and Ar10+ charge states appeared with decreasing preexpansion gas temperature. A nonlinear increase of X-ray line emission from Ar7+, Ar8+, and Ar9+ was observed with cooling, which saturated below a certain temperature. The drastic change in the spectrum is attributed to efficient collisional heating and collisional ionization of growing, small- to medium-sized (102–103 atoms) Ar clusters from the cooled jet. When the laser pulse was extended from 25 to 100 fs we observed considerably stronger emission on lines from high charge states, such as Ar8+, Ar9+, and Ar10+, which suggests that the resonance absorption condition could be reached for the 100-fs pulse.
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12

Rodríguez del Río, Pablo. "AR101 prevents peanut allergy reactions in highly peanut-allergic children." Journal of Pediatrics 208 (May 2019): 294–97. http://dx.doi.org/10.1016/j.jpeds.2019.02.050.

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13

Hamilton, Raymond F., Shuji Tsuruoka, Nianqiang Wu, Michael Wolfarth, Dale W. Porter, Melisa Bunderson-Schelvan, and Andrij Holian. "Length, but Not Reactive Edges, of Cup-stack MWCNT Is Responsible for Toxicity and Acute Lung Inflammation." Toxicologic Pathology 46, no. 1 (September 25, 2017): 62–74. http://dx.doi.org/10.1177/0192623317732303.

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Multiwalled carbon nanotube (MWCNT) toxicity after inhalation has been associated with size, aspect ratio, rigidity, surface modification, and reactive oxygen species production. In this study, we investigated a series of cup-stacked MWCNT prepared as variants of the Creos 24PS. Mechanical chopping produced a short version (AR10) and graphitization to remove active reaction sites by extreme heat (2,800°C; Creos 24HT) to test the contribution of length and alteration of potential reaction sites to toxicity. The 3 MWCNT variants were tested in vitro in a human macrophage–like cell model and with C57BL/6 alveolar macrophages for dose-dependent toxicity and NLRP3 inflammasome activation. The 24PS and 24HT variants showed significant dose-dependent toxicity and inflammasome activation. In contrast, the AR10 variant showed no toxicity or bioactivity at any concentration tested. The in vivo results reflected those observed in vitro, with the 24PS and 24HT variants resulting in acute inflammation, including elevated polymorphonuclear counts, Interleukin (IL)-18, cathepsin B, and lactate dehydrogenase in isolated lung lavage fluid from mice exposed to 40 µg MWCNT. Taken together, these data indicate that length, but not the absence of proposed reaction sites, on the MWCNT influences particle bioactivity.
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14

McKay, Gordon, Mohammed El-Geundi, and Mamdouh M. Nassar. "Adsorption Model for the Removal of Acid Dyes from Effluent by Bagasse Pith Using a Simplified Isotherm." Adsorption Science & Technology 15, no. 10 (November 1997): 737–52. http://dx.doi.org/10.1177/026361749701501002.

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The adsorption of two acid dyes, viz. Acid Red AR114 and Acid Blue AB25, on to bagasse pith, a waste material from the sugar cane industry, has been studied. Equilibrium isotherms and agitated batch contact time studies have been carried out. A mass-transfer model has been used based on a Langmuir-type isotherm at maximum saturation. This simple or pseudo-irreversible isotherm and the assumption of pore diffusion enables a pore diffusion mass-transfer model to theoretically predict the experimental concentration decay curves very rapidly.
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15

Silva, Nathalie, Olga Santos, Felipe Morais, Ilan Gottlieb, Macelo Hadlich, Tamara Rothstein, Milena Tauil, Nathalia Veras, Mario Vaisman, and Patricia de Fátima Teixeira. "Subclinical hypothyroidism represents an additional risk factor for coronary artery calcification, especially in subjects with intermediate and high cardiovascular risk scores." European Journal of Endocrinology 171, no. 3 (September 2014): 327–34. http://dx.doi.org/10.1530/eje-14-0031.

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ObjectiveSeveral studies have suggested an association between subclinical hypothyroidism (SCH) and increased cardiovascular risk. The aim of this study was to evaluate the presence of coronary artery disease (CAD) in asymptomatic patients with SCH by measuring the coronary artery calcium score (CACS).DesignA total of 222 asymptomatic subjects (103 SCH and 119 euthyroid (EU)), who were between the ages of 35 and 65 years and had no previous history of CAD, were enrolled for this cross-sectional analysis.MethodsThe criteria for SCH included a confirmed normal serum free thyroxine and high TSH levels. Lipid profile, Framingham risk score (FRS) and CACS analyses were performed for all subjects.ResultsThe SCH and EU groups were comparable with respect to age, gender, BMI and frequency of diabetes, systemic arterial hypertension, hypercholesterolaemia and smoking. There was no difference in the median CACS between the SCH and EU groups. However, in the subgroup of subjects with intermediate/high FRS (AR10y≥10%), CACS was higher in the SCH subjects compared with EU subjects (EU vs SCH, 0.0 (57.0) vs 23.0 (161.5);P=0.045). Multivariate analysis revealed that the risk for CACS >100 was independently associated with male gender, age >55 years, and the presence of simultaneous SCH and AR10y≥10% (OR=87.5 (CI=2.1–3500);P=0.001). Serum TSH was positively correlated with CACS, especially in intermediate/high FRS subjects (rs=0.301,P=0.045).ConclusionsIt was demonstrated that SCH represents an additional risk factor for CAD, notably in intermediate and high FRS subjects.
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16

Bollwein, H., F. Janett, and M. Kaske. "Effects of nutrition on sexual development of bulls." Animal Reproduction 14, no. 3 (2017): 607–13. http://dx.doi.org/10.21451/1984-3143-ar1004.

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Liu, Yusheng, and Wei Wang. "Inhibition of Pontine CaMKII Alleviates Sevoflurane-Induced Long-Term Memory Impairment in Rats." Science Insights 10, no. 1 (October 10, 2014): 266–72. http://dx.doi.org/10.15354/si.14.ar101.

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18

Bolick, Maria, Qingsong Zhao, Shiqin Xu, Mary Pathak, Aili Sunny, and Fuzhou Wang. "Pathological Contribution of Spinal Macrophage Migration Inhibitory Factor to Neuropathic Hypersensitivity through Interacting with TNF-α in the Rat." Science Insights 10, no. 2-3 (November 28, 2014): 283–90. http://dx.doi.org/10.15354/si.14.ar109.

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19

Xu, Yunjie. "How to Cultivate Students’ Core Literacy in the Unit Introduction Course? Take Middle School English as an Example." Science Insights Education Frontiers 3, no. 2 (August 30, 2019): 323–30. http://dx.doi.org/10.15354/sief.19.ar102.

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20

Kang, Le, Fulin Li, and Yan Li. "Identifying Factors that Influence International Student Mobility in Chinese Higher Education Institutions." Science Insights Education Frontiers 4, no. 1 (October 30, 2019): 339–54. http://dx.doi.org/10.15354/sief.19.ar107.

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21

Agatep, John Lenon E., and Domingo C. Edaño. "Internet Addiction Management among Students of AMA Computer Colleges in Region III, Philippines." Science Insights 2018, no. 2018 (June 5, 2018): 1–10. http://dx.doi.org/10.15354/si.18.ar103.

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Wang, Fuzhou. "Homeostatic Synaptic Plasticity: Balanced by COX2-PGE2 System to a New Setpoint." Science Insights 1, no. 2 (July 15, 2013): 20–23. http://dx.doi.org/10.15354/si.13.ar004.

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The setpoint of neural activity plays a critical role in maintaining the complex neural circuits into stable activities. Homeostatic synaptic plasticity is a major component of the setpoint theory that dynamically adjusts synaptic strengths. Cyclooxy-genase 2 (COX 2) is rapidly upregulated in inflammatory episodes after nervous injury and its product prostaglandin E2 (PGE2) exerts contrast functions in the nervous system by working on the homeostatic plasticity. New data revealed that COX2-PGE2 system takes an essential part in balancing excitation and inhibition of the synaptic activities at a new setpoint that finally is maintained by the homeostatic synaptic plasticity.
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23

Fang, Chao, and Bin Huang. "Can Information Technology Promote Academic Performance of School-aged Children? An Empirical Study Based on CEPS." Best Evidence of Chinese Education 2, no. 2 (July 31, 2019): 209–27. http://dx.doi.org/10.15354/bece.19.ar1045.

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Xie, Jing, and Yanguo Tu. "An Investigation into the Impact of Mindfulness Education on Children Development – Based on the Mindfulness Experiment on 5th Graders of D primary School in W City." Best Evidence of Chinese Education 2, no. 2 (July 31, 2019): 229–42. http://dx.doi.org/10.15354/bece.19.ar1049.

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Gao, Xiang, and Haiping Xue. "Family Background, Parent Involvement, and Shadow Education Participation of Middle School Students: Empirical Analysis from CEPS2015 Data." Best Evidence in Chinese Education 7, no. 1 (January 29, 2021): 893–905. http://dx.doi.org/10.15354/bece.21.ar004.

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Using the 2015 data of the China Education Panel Survey (CEPS), the relationship between family socioeconomic background, parent involvement, and shadow education participation was explored through structural equations. The results showed that: parent involvement strengthened shadow education participation; parent involvement played a part in the mediating role in the influence of family socioeconomic background on shadow education participation. Parent involvement activates the advantage of family socioeconomic background. Families with high socioeconomic backgrounds are more active in participating in shadow education, and families of different strata are divided into opportunities for participation in shadow education.
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26

Hamasha, Safeia M., and Yasmeen Abu-Nassar. "Theoretical spectral analysis of Ar ions from Ar9+ to Ar14+." Journal of Quantitative Spectroscopy and Radiative Transfer 266 (May 2021): 107567. http://dx.doi.org/10.1016/j.jqsrt.2021.107567.

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27

Assa'ad, A., M. Welch, S. Acaster, K. Gallop, J. DeVries, N. Griffin, K. Brown, and J. Bird. "TREATMENT SATISFACTION WITH AR101 PEANUT ALLERGY ORAL IMMUNOTHERAPY: A MIXED METHODS STUDY." Annals of Allergy, Asthma & Immunology 121, no. 5 (November 2018): S53. http://dx.doi.org/10.1016/j.anai.2018.09.170.

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Shreffler, Wayne, Stacie Jones, Stanley Fineman, Noelle Griffin, Andrea Vereda, Alex Smith, Kari Brown, Daniel Adelman, and A. Wesley Burks. "Identifying Demographics and Baseline Clinical Characteristics Associated with Safety Outcomes During AR101 Therapy." Journal of Allergy and Clinical Immunology 145, no. 2 (February 2020): AB132. http://dx.doi.org/10.1016/j.jaci.2019.12.525.

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Ameera, N., A. Shuhaimi, S. Najwa, K. M. Hakim, M. Mazwan, M. Sobri, M. H. Mamat, M. Z. Musa, and M. Rusop. "Effects of Oxygen Gas Composition on Nanocolumnar Zinc Oxide Properties Deposited by RF Magnetron Sputtering." Advanced Materials Research 832 (November 2013): 783–86. http://dx.doi.org/10.4028/www.scientific.net/amr.832.783.

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Nanocolumnar ZnO was successfully deposited on glass substrate by RF magnetron sputtering. It was performed with a ZnO target with 99.999% purity at RF power of 200 W. The growth temperature was specified at 500°C, with total deposition time of 1 hour. The effects of oxygen gas composition during sputtering process was investigated. Argon to oxygen ratio was varied at Ar10:Ox5, Ar8:Ox7 and Ar5:x10 sccm. Optical characterization on samples indicated that the transmittance though visible range is higher than 80%. Based on morphological property obtained, higher oxygen content exhibited better uniformity and surface roughness. This is due to the reduction of oxygen vacancies in the ZnO layer.
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GOU, BINGCONG, YIDONG LIU, and FENG WANG. "ELECTRON CORRELATION EFFECTS FOR DOUBLY-EXCITED STATES OF Be-LIKE Ar14+ ION." International Journal of Modern Physics B 18, no. 17n19 (July 30, 2004): 2590–94. http://dx.doi.org/10.1142/s0217979204025725.

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The energies, radiative and Auger rates of the doubly excited states of Be-like Ar 14+ ion are studied by using the multi-configuration-interaction method and model potential method. The doubly excited states of Be-like Ar 14+ are labeled by the quantum numbers K, T and A to show the systematic regularity. The results show that the spectroscopy of Be-like ions is different from that of He-like ions because of the polarization and core penetration effects from the 1s2 core electrons.
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Dong, C. Z., C. Z. Dong, S. Fritzsche, B. Fricke, and W. D. Sepp. "Ab-initio Calculations for Forbidden M1 Transitions in Ar13+ and Ar14+ Ions." Physica Scripta T92, no. 1 (2001): 294–96. http://dx.doi.org/10.1238/physica.topical.092a00294.

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32

Ishikawa, Yasuyuki, Hideo Sekino, and Robert C. Binning. "Relativistic many-body perturbation theory calculations on Be, Ne6+, Ar14+ AND Ne." Chemical Physics Letters 160, no. 2 (August 1989): 206–11. http://dx.doi.org/10.1016/0009-2614(89)87583-9.

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Melis, Claudio, Sarah C. R. Lummis, and Carla Molteni. "Molecular Dynamics Simulations of GABA Binding to the GABAC Receptor: The Role of Arg104." Biophysical Journal 95, no. 9 (November 2008): 4115–23. http://dx.doi.org/10.1529/biophysj.107.127589.

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34

Kim, E., B. Vickery, A. Radwan, and W. Burks. "O055 Immunologic effects of AR101 during characterized oral desensitization immunotherapy (CODIT) for peanut allergy." Annals of Allergy, Asthma & Immunology 117, no. 5 (November 2016): S18. http://dx.doi.org/10.1016/j.anai.2016.09.416.

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Ago, Hideo, Noriaki Okimoto, Yoshihide Kanaoka, Gentaro Morimoto, Yoko Ukita, Hiromichi Saino, Makoto Taiji, and Masashi Miyano. "Structure basis of Leukotriene C4 Synthase and its isophtalate inhibitors." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C800. http://dx.doi.org/10.1107/s2053273314091992.

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Leukotriene (LT) C4 synthase (LTC4S) is a key enzyme for the production of cysteinyl leukotrienes, LTC4, LTD4 and LTE4, which are relevance to asthma and allergy. LTC4S catalyzes the conjugation of glutathione (GSH) to LTA4. The crystal structure of LTC4S complex with GSH revealed the active sites locate at the interfaces of adjacent monomer in trans-membrane homo-trimer [1]. The unique U-shaped GSH binds the inner hydrophilic interface cavity and the amphiphilic LTA4 was proposed to bind in the hydrophobic V-shaped crevasse on the interface of the trimer hydrophobic surface. Two essential arginine residues was proved to exert as acid-base catalysis at the both sides of two substrates in highly regio- and stereo-selective manner enzymatically and crystallographically [2]. The architecture of the catalysis with Arg104 and Arg31 residues is the unique among various Glutathione-S-transferases. Arg104 activates and stabilizes the thiorate anaion of the bound GSH and Arg31 stabilize and activate epoxy of the other substrate LTA4, and each mutation causes not only reduction of activity but also each substrate binding affinity substantially. Furthermore, the putative LTA4 binding position was confirmed using the anomalous signal of selenium of the bound seleno-dodecylmaltoside (Se-DDM) at the V-shaped crevasse. To identify leads for novel therapeutics, we attempted to search competitive inhibitors against the unique shaped GSH binding site to discriminate the GSH binding sites of other GSTs that accommodate only its extending backbone conformer [3]. Hierarchical in silico screenings of 6 million compounds provided 300,000 dataset for docking, and after energy minimization based on the crystal structure of LTC4S, 111 compounds were selected as candidates for a competitive inhibitor to glutathione. 5-(5-Methylene-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid moiety was identified to inhibit LTC4 formation both an enzyme assay and a whole-cell assay. Finally, 5-((Z)-5-((E)-2-methyl-3-phenylallylidene)-4-oxo-4,5-dihydrothiazol-2-ylamino) isophthalic acid was found to be the most potent inhibitor with 1.9 µM of IC50, and in the whole-cell assay to inhibit LTC4 synthesis with cell permeability in a concentration dependent manner.
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36

Deschildre, A., E. R. Sher, J. O. B. Hourihane, W. W. Carr, K. Beyer, N. M. Griffin, A. Vereda, et al. "Safety and efficacy comparison : ARTEMIS and PALISADE phase 3 studies of AR101 in peanut allergy." Revue Française d'Allergologie 61, no. 5 (September 2021): 339–40. http://dx.doi.org/10.1016/j.reval.2020.09.009.

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37

Ben Ali, Hayet, Salma Besbes Hentati, Salem S. Al-Deyab, Mohamed Rzaigui, and M'henni Mohamed Farouk. "The Influence of the Chemical Structures of Chitosan and Acid Dye on the Adsorption Process." E-Journal of Chemistry 9, no. 4 (2012): 2415–23. http://dx.doi.org/10.1155/2012/706938.

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The objective of this paper is the study of the influence of the chemical structures of adsorbent and adsorbate on the adsorption process. By using of crab shell chitosan (CC) and deep-pink shrimp chitosan (CP) for removal of acid 183 and AR114 from aqueous solutions, it is shown that CP, which corresponds to the highest molecular weight, is the most efficient adsorbent material. In addition, the best extent of decolorization is obtained for AR 183 that is the smallest molecule. Langmuir model represents the best fit of the experimental data, indicating monolayer coverage of chitosan outer surface. Pseudo-second order kinetic model describes accurately the adsorption processes, suggesting chemical rate limiting steps. The positive values of the enthalpy changes indicated endothermic attachment of dyes to the biomaterials. CP/AR183 system corresponds to the most energetically favorable phenomenon. Besides, desorption of AR from chitosan was found to be very low in acidic aqueous medium for all couples.
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Sher, E., J. Hourihane, W. Carr, K. Beyer, N. Griffin, A. Vereda, D. Norval, G. du Toit, D. Adelman, and E. Kim. "P303 SAFETY AND EFFICACY COMPARISON: ARTEMIS AND PALISADE PHASE 3 STUDIES OF AR101 IN PEANUT ALLERGY." Annals of Allergy, Asthma & Immunology 123, no. 5 (November 2019): S47—S48. http://dx.doi.org/10.1016/j.anai.2019.08.310.

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39

Bird, J., L. Sher, N. Griffin, A. Vereda, A. Smith, and J. Ohayon. "P308 RESPONSE TO AR101 BY BASELINE PEANUT-SPECIFIC IGE AND SKIN PRICK TEST: RESULTS FROM PALISADE." Annals of Allergy, Asthma & Immunology 123, no. 5 (November 2019): S49. http://dx.doi.org/10.1016/j.anai.2019.08.315.

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40

Lanser, Bruce, Stephanie Leonard, Noelle Griffin, Andrea Vereda, Alex Smith, and Thomas Casale. "Effect of Demographics and Baseline Clinical Characteristics on the Treatment Response to AR101: Results From PALISADE." Journal of Allergy and Clinical Immunology 145, no. 2 (February 2020): AB138. http://dx.doi.org/10.1016/j.jaci.2019.12.442.

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41

Zigmont, E., R. Zawadzki, K. Beyer, A. Burks, T. Casale, J. Hourihane, S. Jones, A. Vereda, B. Vickery, and D. Adelman. "P339 International comparisons of patient characteristics in a phase 3 study of AR101 for peanut allergy." Annals of Allergy, Asthma & Immunology 119, no. 5 (November 2017): S81. http://dx.doi.org/10.1016/j.anai.2017.08.230.

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42

Burks, A., T. Casale, K. Beyer, L. DuToit, S. Jones, J. Hourihane, W. Shreffler, et al. "AGE-RELATED FINDINGS FROM THE PEANUT ALLERGY ORAL IMMUNOTHERAPY STUDY OF AR101 FOR DESENSITIZATION (PALISADE) STUDY." Annals of Allergy, Asthma & Immunology 121, no. 5 (November 2018): S4. http://dx.doi.org/10.1016/j.anai.2018.09.010.

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43

Kim, Seon Hee, Christopher H. Evans, Sunyoung Kim, Thomas Oligino, Steven C. Ghivizzani, and Paul D. Robbins. Arthritis Research 2, no. 4 (2000): 293. http://dx.doi.org/10.1186/ar104.

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44

Garg, Alok, Vikas K. Sangal, and Pramod K. Bajpai. "Photocatalytic Treatment of Binary Mixture of Dyes using UV/TiO2 Process: Calibration, Modeling, Optimization and Mineralization Study." International Journal of Chemical Reactor Engineering 15, no. 2 (April 1, 2017). http://dx.doi.org/10.1515/ijcre-2015-0220.

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Abstract Photocatalytic treatment of a binary dye mixture (Acid Blue 113 (AB113) and Acid Red 114 (AR114)) has been done in a slurry pond reactor using TiO2 as a photocatalyst with UV light irradiation (UV-C). Two different methods, namely multivariate calibration and first order derivative spectrophotometric were used to quantify each dye separately in binary dye solutions. The behavior of the photocatalytic degradation of a binary dye mixture was predicted using an artificial neural network (ANN) model. Five process parameters (initial concentration of AB113 dye, initial concentration of AR114 dye, TiO2 dose, initial pH of the dye mixture and time were used as inputs and decolorization efficiency of AB113 and AR114 were used as output of the ANN. The parametric optimization has been done by the multi-response optimization with desirability function methodology. Optimization by Central Composite Design (CCD) effectively handles the relations among optimizing process variables and its prediction concurred well with the experimental run and artificial neural network (ANN) model. The reaction kinetic rates of decolorization of both dyes (AB113 and AR114) were found to be first order. Total organic carbon (TOC) removal and possible reaction pathway show the total mineralization of both dyes in binary dye mixture.
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45

Breedveld, Ferdinand C. Arthritis Research 2, no. 4 (2000): 268. http://dx.doi.org/10.1186/ar100.

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46

Boyle, David L., Sanna Rosengren, William Bugbee, Arthur Kavanaugh, and Gary S. Firestein. Arthritis Research & Therapy 5, no. 6 (2003): R352. http://dx.doi.org/10.1186/ar1004.

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47

van Laar, Jacob M. Arthritis Research 2, no. 4 (2000): 270. http://dx.doi.org/10.1186/ar101.

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48

Chuang, I.-Chuan, Chien-Ming Jhao, Chih-Hsun Yang, Hsien-Chang Chang, Chien-Wen Wang, Cheng-Yuan Lu, Yao-Jen Chang, Sheng-Han Lin, Pao-Lin Huang, and Lin-Cheng Yang. Arthritis Research & Therapy 6, no. 1 (2004): R7. http://dx.doi.org/10.1186/ar1014.

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49

Tyndall, Alan, and Alois Gratwohl. Arthritis Research 2, no. 4 (2000): 276. http://dx.doi.org/10.1186/ar102.

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50

Gilbert, Sophie J., Victor C. Duance, and Deborah J. Mason. Arthritis Research & Therapy 6, no. 1 (2004): R46. http://dx.doi.org/10.1186/ar1024.

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