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Journal articles on the topic 'Archaic pathologies'

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1

Lincoln-Babb, Lorrie. "The Matty Canyon Population: Dental Observations of Late Archaic Individuals from Southern Arizona." Dental Anthropology Journal 9, no. 2 (2018): 10–12. http://dx.doi.org/10.26575/daj.v9i2.237.

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Skeletal and dental material from the largest known burial population from the Late Archaic Period of southern Arizona was analyzed (Minturn and Lincoln-Babb, n.d.). Minturn performed the skeletal analyses, including the standard observations for age, sex, and pathologies. The dental analyses support a mixed economy subsistence of hunting-gathering and agriculture. This conclusion is based on observations for caries, enamel chipping, abscessing, and enamel hypoplasia.
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2

Rosado, Maria Araya. "Dental Health and Diet of Two Prehistoric Populations from Chile's Semiarid North." Dental Anthropology Journal 13, no. 1 (2018): 2–9. http://dx.doi.org/10.26575/daj.v13i1.199.

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This investigation examines dental health and diet of two prehistoric populations from Chile's semiarid north. Trace element and dental paleopathological analyses have been conducted on skeletal remains of hunter-gatherers of the Archaic period (n=99, ca. 1,800 BC) and agriculturalists of the Diaguita period (n=82, 1,000-1,500 AD). Archaeological and historical evidence indicates that the Diaguita diet primarily incorporated cultivated and wild plants, but also included pastoralism and marine resources. By contrast, the subsistence of Archaic peoples was primarily based on marine resources. Co
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Syutkina, T. A. "Paleopathological analysis of the cranial samples from Pre-Columbian Cuba." VESTNIK ARHEOLOGII, ANTROPOLOGII I ETNOGRAFII, no. 1(60) (March 15, 2023): 139–50. http://dx.doi.org/10.20874/2071-0437-2023-60-1-12.

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The article presents a paleopathological analysis of two cranial samples from pre-Columbian Cuba: the Si-boney (also known as Archaic) sample consisting of 40 individuals and the Taíno sample composed of 27 indi-viduals. The Siboney are believed to have arrived to Cuba around 5000 years ago, and the Taíno inhabited the island since approximately 500 AD until decimation by the newcomers from the Old World. All the Taíno crania exhibit fronto-occipital artificial deformation. The main focus of the study is oral pathologies and bone abnormali-ties observed in the samples and how these reflect the
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Silva, Ana Maria, Ana Catarina Sousa, and Chris Scarre. "A closer look at the forgotten bones of the Dolmen of Pedras Grandes (Odivelas, Portugal). (Examining old human remains 7)." SPAL. Revista de Prehistoria y Arqueología de la Universidad de Sevilla 2, no. 30 (2021): 20–46. http://dx.doi.org/10.12795/spal.2021.i30.16.

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The Dolmen of Pedras Grandes (Odivelas, Lisboa, Portugal) was discovered and excavated at the end of the 19th century by Carlos Ribeiro. In 2004, this monument was re-excavated by Rui Boaventura and a complete study was conducted. The Dolmen of Pedras Grandes presents a polygonal chamber and a very short passage and may have had a short period of burial activity in the 4thmillennium as indicated by the radiocarbon dates and the “archaic” artefacts. The relative and absolute dating enable us to assign this monument to the initial phase of megalithic funerary monumentality in south-central Portu
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N, Manseur. "Phobia." Psychology & Psychological Research International Journal 9, no. 4 (2024): 1–3. https://doi.org/10.23880/pprij-16000440.

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Phobias, multiple and very varied, are usually referred to neurotic functioning. However, phobogenic processes are located at the crossroads of various pathologies of mental functioning, and certain phobias can reflect more archaic functioning. Phobias are linked to anxiety, an unpleasant affect intrinsic to the human condition. Although not all anxieties become phobias, it is because there is prior anxiety that a phobia is created. As soon as, invested impulsively, the ego and the object are distinguished, anxiety is experienced. If this can be linked to a representation, then, thus weighted,
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Michel, Jean-Baptiste. "Phylogenic Determinants of Cardiovascular Frailty, Focus on Hemodynamics and Arterial Smooth Muscle Cells." Physiological Reviews 100, no. 4 (2020): 1779–837. http://dx.doi.org/10.1152/physrev.00022.2019.

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The evolution of the circulatory system from invertebrates to mammals has involved the passage from an open system to a closed in-parallel system via a closed in-series system, accompanying the increasing complexity and efficiency of life’s biological functions. The archaic heart enables pulsatile motion waves of hemolymph in invertebrates, and the in-series circulation in fish occurs with only an endothelium, whereas mural smooth muscle cells appear later. The present review focuses on evolution of the circulatory system. In particular, we address how and why this evolution took place from a
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7

Karapetian, Marina, Vladimir Kufterin, and Mikhail Chaplygin. "HUMAN SKELETAL REMAINS NEWLY EXCAVATED AT KARANAYEVSKY KURGAN CEMETERY OF THE SRUBNAYA CULTURE." Nizhnevolzhskiy Arheologicheskiy Vestnik 23, no. 1 (2024): 5–26. http://dx.doi.org/10.15688/nav.jvolsu.2024.1.1.

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Introduction. This paper presents results of an anthropological and paleopathological studies of newly excavated materials from the Karanayevsky cemetery located in the Southwestern Bashkortostan and attributed to Srubnaya culture. The goal of this study was to introduce new data from kurgan 2, as well as to compare this sample with the samples from other Karanayevsky kurgans, and with synchronous population characteristics of the region. Discussion involves skeletal material from 12 individual burials (nine children and three adults). Methods. Sex, age and the state of preservation/completene
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8

Gangemi, Ezio Nicola, Dario Gregori, Paola Berchialla, et al. "Epidemiology and Risk Factors for Pathologic Scarring After Burn Wounds." Archives of Facial Plastic Surgery 10, no. 2 (2008): 93–102. http://dx.doi.org/10.1001/archfaci.10.2.93.

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9

Brindzaitė, Rūta. "Life Across the River: Exploring the Impact of Urbanisation in 18th–19th Century Panevėžys." Archaeologia Lituana 21 (December 28, 2020): 117–31. http://dx.doi.org/10.15388/archlit.2019.21.7.

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Studies aimed at considering the impact of industrialisation, urbanisation and modernisation on human health in 19th-century society are becoming increasingly relevant. Although it is exceptionally rare to encounter human skeletal material from the 19th century in present-day Lithuania, this study explores whether changes which occurred in that century had any impact on human health. This research presents the preliminary results of an anthropological analysis of the human remains discovered in Panevėžys Cemetery, with material spanning the 18th–19th centuries. In total, 90 individuals were ex
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10

Giani, Micaela, Carmen Pire, and Rosa María Martínez-Espinosa. "Bacterioruberin: Biosynthesis, Antioxidant Activity, and Therapeutic Applications in Cancer and Immune Pathologies." Marine Drugs 22, no. 4 (2024): 167. http://dx.doi.org/10.3390/md22040167.

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Halophilic archaea, also termed haloarchaea, are a group of moderate and extreme halophilic microorganisms that constitute the major microbial populations in hypersaline environments. In these ecosystems, mainly aquatic, haloarchaea are constantly exposed to ionic and oxidative stress due to saturated salt concentrations and high incidences of UV radiation (mainly in summer). To survive under these harsh conditions, haloarchaea have developed molecular adaptations including hyperpigmentation. Regarding pigmentation, haloarchaeal species mainly synthesise the rare C50 carotenoid called bacterio
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11

SADET-BOURGETEAU, S., and V. JULLIAND. "La diversité de l’écosystème microbien du tractus digestif équin." INRAE Productions Animales 25, no. 5 (2012): 407–18. http://dx.doi.org/10.20870/productions-animales.2012.25.5.3228.

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Le gros intestin (caecum et côlon) des équins héberge un microbiote abondant et divers dont une fonction essentielle est la dégradation et la fermentation des parois végétales ingérées en produits directement utilisables par l’hôte. Ce microbiote est composé de cinq grandes communautés microbiennes (protozoaires, bactéries, champignons, Archaea et virus) parmi lesquelles les bactéries ont été les plus étudiées. Ces communautés sont spécifiques de l’espèce équine. La diversité des protozoaires comme celle des champignons et des virus a été décrite du point de vue taxonomique mais leur implicati
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12

Del Castillo Falconi, Victor M., Karla Torres-Arciga, Genaro Matus-Ortega, José Díaz-Chávez, and Luis A. Herrera. "DNA Methyltransferases: From Evolution to Clinical Applications." International Journal of Molecular Sciences 23, no. 16 (2022): 8994. http://dx.doi.org/10.3390/ijms23168994.

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DNA methylation is an epigenetic mark that living beings have used in different environments. The MTases family catalyzes DNA methylation. This process is conserved from archaea to eukaryotes, from fertilization to every stage of development, and from the early stages of cancer to metastasis. The family of DNMTs has been classified into DNMT1, DNMT2, and DNMT3. Each DNMT has been duplicated or deleted, having consequences on DNMT structure and cellular function, resulting in a conserved evolutionary reaction of DNA methylation. DNMTs are conserved in the five kingdoms of life: bacteria, protis
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13

Santoro, Rossella, Antonio Romano, Maria Cristina Morcaldi, Fausto Fiori, and Federica Di Spirito. "Microbiota Alterations in Patients with Mucous Membrane Pemphigoid and Pemphigus Vulgaris: A Systematic Review." Applied Sciences 13, no. 7 (2023): 4377. http://dx.doi.org/10.3390/app13074377.

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The human oral cavity comprises an extensive range of microorganisms, viruses, bacteria, fungi, archaea, and protozoa, each having a particular role and interacting with each other and with the host in sickness or health. Changes in the microbiome composition can be crucial in balancing health and disease, locally and systemically. Various microbial species in commensal relationships form the oral microbiota, and when this commensalism undergoes variations the immune system can be pushed towards the activation of inflammatory and autoimmune processes. Through a systematic review of the literat
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14

Ávila-Román, Javier, Patricia Gómez-Villegas, Carla C. C. R. de Carvalho, et al. "Up-Regulation of the Nrf2/HO-1 Antioxidant Pathway in Macrophages by an Extract from a New Halophilic Archaea Isolated in Odiel Saltworks." Antioxidants 12, no. 5 (2023): 1080. http://dx.doi.org/10.3390/antiox12051080.

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The production of reactive oxygen species (ROS) plays an important role in the progression of many inflammatory diseases. The search for antioxidants with the ability for scavenging free radicals from the body cells that reduce oxidative damage is essential to prevent and treat these pathologies. Haloarchaea are extremely halophilic microorganisms that inhabit hypersaline environments, such as saltworks or salt lakes, where they have to tolerate high salinity, and elevated ultraviolet (UV) and infrared radiations. To cope with these extreme conditions, haloarchaea have developed singular mecha
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15

Kodio, Aly, Estelle Menu, and Stéphane Ranque. "Eukaryotic and Prokaryotic Microbiota Interactions." Microorganisms 8, no. 12 (2020): 2018. http://dx.doi.org/10.3390/microorganisms8122018.

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The nature of the relationship between the communities of microorganisms making up the microbiota in and on a host body has been increasingly explored in recent years. Microorganisms, including bacteria, archaea, viruses, parasites and fungi, have often long co-evolved with their hosts. In human, the structure and diversity of microbiota vary according to the host’s immunity, diet, environment, age, physiological and metabolic status, medical practices (e.g., antibiotic treatment), climate, season and host genetics. The recent advent of next generation sequencing (NGS) technologies enhanced ob
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16

Khayatt, Barzan Ibrahim. "Bioinformatics Approach for Metabolism Pathways Curation: Carbohydrate Metabolism and TCA Cycle in the Archaeon Sulfolobus solfataricus P2." Journal of Biotechnology Research Center 17, no. 1 (2023): 5–16. http://dx.doi.org/10.24126/jobrc.2023.17.1.692.

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Background: Metabolic and genomic informatics integrations in organism-specific databases require comprehensive and intensive efforts. PathoLogic, a component of the Pathway Tools software package can create complete Pathway/Genome Databases (PGDBs) from genomic sequence and annotation files for any organism. This tool can predict the metabolic pathways using MetaCyc as a reference knowledge base. This work aimed to apply a bioinformatics approach to curate a PGDB created for the Crenarchaeon Sulfolobus solfataricus P2. This archaeon grows optimally at 80o C and pH 2-4. The complete genome of
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17

Peña-Guerrero, José, Celia Fernández-Rubio, Alfonso T. García-Sosa, and Paul A. Nguewa. "BRCT Domains: Structure, Functions, and Implications in Disease—New Therapeutic Targets for Innovative Drug Discovery against Infections." Pharmaceutics 15, no. 7 (2023): 1839. http://dx.doi.org/10.3390/pharmaceutics15071839.

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The search for new therapeutic targets and their implications in drug development remains an emerging scientific topic. BRCT-bearing proteins are found in Archaea, Bacteria, Eukarya, and viruses. They are traditionally involved in DNA repair, recombination, and cell cycle control. To carry out these functions, BRCT domains are able to interact with DNA and proteins. Moreover, such domains are also implicated in several pathogenic processes and malignancies including breast, ovarian, and lung cancer. Although these domains exhibit moderately conserved folding, their sequences show very low cons
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18

K, Houston, Alessandro ND, and Johnson DA. "From The Mouth to the Gut: The Oral Microbiome's Role in Promoting Gastrointestinal Disease." Gastroenterology & Hepatology International Journal 10, no. 1 (2025): 1–8. https://doi.org/10.23880/ghij-16000222.

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The traditional thoughts about oral microbial health have centered around the risks for dental caries, gingivitis and periodontal disease. There has been however ever-increasing data that oral health has significant implications for gastrointestinal health (GI) with strong evidence links the oral microbiome (which includes bacteria, fungi, virus, archaea), with an ever-increasing spectrum of metabolic, inflammatory and neoplastic diseases. The oral cavity hosts a diverse range of microorganisms that form a complex ecosystem known as the oral microbiome. While traditionally associated with path
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19

Allen, Carl E. "Acquired Hematologic Disorders of Ras-MAPK Activation." Blood 132, Supplement 1 (2018): SCI—42—SCI—42. http://dx.doi.org/10.1182/blood-2018-99-109380.

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Abstract Histiocytic disorders represent a collection of conditions characterized by aberrant function, differentiation and/or proliferation of cells of the mononuclear phagocyte system (MPS). "Histiocyte" is an archaic term (meaning "tissue cell") used to describe phagocytic cells with mononuclear morphology. Clinical approaches to histiocytic disorders have historically been challenged by incomplete understanding of mechanisms of pathogenesis, with debate over classification as cancer versus immune dysregulation. Langerhans cell histiocytosis (LCH), the most common histiocytic disorder, pres
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20

Pisano, Massimo, Francesco Giordano, Giuseppe Sangiovanni, Nicoletta Capuano, Alfonso Acerra, and Francesco D’Ambrosio. "The Interaction between the Oral Microbiome and Systemic Diseases: A Narrative Review." Microbiology Research 14, no. 4 (2023): 1862–78. http://dx.doi.org/10.3390/microbiolres14040127.

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Background: The human being is defined as a ‘superorganism’ since it is made up of its own cells and microorganisms that reside inside and outside the human body. Commensal microorganisms, which are even ten times more numerous than the cells present in the body, perform very important functions for the host, as they contribute to the health of the host, resist pathogens, maintain homeostasis, and modulate the immune system. In the mouth, there are different types of microorganisms, such as viruses, mycoplasmas, bacteria, archaea, fungi, and protozoa, often organized in communities. The aim of
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21

Landon, Blair V., Ronan J. Kelly, Ali H. Zaidi, et al. "Abstract 3374: Circulating cell-free tumor DNA dynamics capture minimal residual disease with neoadjuvant immune checkpoint blockade plus chemoradiotherapy for patients with operable esophageal/gastroesophageal junction cancer." Cancer Research 83, no. 7_Supplement (2023): 3374. http://dx.doi.org/10.1158/1538-7445.am2023-3374.

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Abstract Introduction: There is a critical need to incorporate molecular assessments of minimal residual disease (MRD) during neoadjuvant immunotherapy, in order to identify individuals at high risk for disease recurrence based on analyses of circulating cell-free tumor DNA (ctDNA) landscapes. Here we employed longitudinal liquid biopsies to dynamically assess clinical outcomes with neoadjuvant immuno-chemoradiotherapy in patients with esophageal/gastroesophageal junction (E/GEJ) cancer. Methods: We utilized targeted error-correction sequencing to perform high-depth ctDNA next-generation seque
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22

Bayati, Saeed, Nour Amirmozafari, Masoud Alebouyeh, Nastaran Farzi, Nasser Ebrahimi Daryani, and Mohammad Reza Zali. "Antibiotic Resistance Among Helicobacter pylori Strains Isolated from Patients with Gastric Pathologies Towards Metronidazole, Clarithromycin, and Ciprofloxacin." Archives of Clinical Infectious Diseases In Press, In Press (2019). http://dx.doi.org/10.5812/archcid.55015.

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23

Rothschild, Bruce, and Martin Haeusler. "Possible vertebral brucellosis infection in a Neanderthal." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-99289-7.

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AbstractThe La Chapelle-aux-Saints 1 skeleton of an old (>60-year-old) male Neanderthal is renowned for the advanced osteoarthritis of its spinal column and hip joint, and their implications for posture and lifestyle in these Mid- to Late Pleistocene humans. Reassessment of the pathologic lesions reveals erosions at multiple non-contiguous vertebrae and reactive bone formation extending far beyond the left hip joint, which suggests the additional diagnosis of brucellosis. This implies the earliest secure evidence of this zoonotic disease in hominin evolution. Brucellosis might have been tra
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24

Kazemi, Mohammad Ali, Nasrin Nikravangolsefid, Hamidreza Abtahi, et al. "COVID-19: Unilateral Involvement of Transplanted Lung, Sparing Contralateral Fibrotic Lung." Archives of Clinical Infectious Diseases 16, no. 4 (2021). http://dx.doi.org/10.5812/archcid.115408.

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Introduction: Organ transplant recipients might be more likely to develop COVID-19, as they receive long-term immunosuppressives and have comorbidities. Case Presentation: Herein, we reported the case of a 32-year-old man with unilateral lung transplantation due to unclassifiable lung fibrosis on pathologic evaluation who presented with cough, fever, and headache. After evaluation with RT-PCR test and chest CT scan, COVID-19 in the previously transplanted lung was diagnosed. However, the other non-transplanted fibrotic lung was not involved. Conclusions: Lack of COVID-19 involvement in the fib
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25

Mathai, Faith, Musa Otieno Ngayo, Simon Muturi Karanja, Ahmed Kalebi, and Raphael Lihana. "Correlation of Quantitative Assay of HBsAg and Hepatitis B Virus DNA Levels Among Chronic HBV Patients Attending Pathologist Lancet Laboratory in Nairobi, Kenya." Archives of Clinical Infectious Diseases 12, no. 4 (2017). http://dx.doi.org/10.5812/archcid.13306.

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26

Mehrabi, Samrad, and Nahid Aram. "The Association Between Pulmonary Tuberculosis and Bronchial Anthracosis." Archives of Clinical Infectious Diseases 17, no. 3 (2022). http://dx.doi.org/10.5812/archcid-128740.

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Background: Anthracosis is a form of pneumoconiosis induced by frequent contact with smoke from biomass, air pollution, charcoal smoke, or dust particles. Objectives: This study aimed to investigate the association between anthracosis and pulmonary tuberculosis (TB). Methods: In this cross-sectional study, 401 patients undergoing bronchoscopy were recruited, and their demographic characteristics, clinical features, bronchoscopy and imaging results, pathologic-cytologic reports, and acid-fast bacilli (AFB) smear were recorded and analyzed. Results: The bronchoscopic results of 220 patients (54.
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27

Nguyen Thi, Huyen, Phuong Phan Thi Minh, and Mandar Reet. "THE ROLE OF THE GUT MICROBIOME IN HUMAN HEALTH." Journal of Medicine and Pharmacy, April 2020, 7–13. http://dx.doi.org/10.34071/jmp.2020.2.1.

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The human microbiota comprises of collective genomes of microbiota, namely protozoa, archaea, eukaryotes, viruses and bacteria that live mainly on and within various sites of the human body, with the highest concentrations being found in gastrointestinal tract. Microbiome plays an important role in host protection against invading pathogens, metabolism and immunity as well as maintaining intestinal homeostasis. Gut microbial imbalance (dysbiosis) may lead to dysfunction of host, thereby contributing to pathogenesis and/or progression of some pathologies. All of them, some of the most noticeabl
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28

Nkera-Gutabara, C. K., R. Kerr, J. Scholefield, S. Hazelhurst, and J. Naidoo. "Microbiomics: The Next Pillar of Precision Medicine and Its Role in African Healthcare." Frontiers in Genetics 13 (April 5, 2022). http://dx.doi.org/10.3389/fgene.2022.869610.

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Limited access to technologies that support early monitoring of disease risk and a poor understanding of the geographically unique biological and environmental factors underlying disease, represent significant barriers to improved health outcomes and precision medicine efforts in low to middle income countries. These challenges are further compounded by the rich genetic diversity harboured within Southern Africa thus necessitating alternative strategies for the prediction of disease risk and clinical outcomes in regions where accessibility to personalized healthcare remains limited. The human
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29

Davison, Mark A., Daniel T. Lilly, Arpan A. Patel, et al. "Clinical presentation and extent of resection impacts progression-free survival in spinal ependymomas." Journal of Neuro-Oncology, March 4, 2024. http://dx.doi.org/10.1007/s11060-024-04623-4.

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Abstract Purpose Primary treatment of spinal ependymomas involves surgical resection, however recurrence ranges between 50 and 70%. While the association of survival outcomes with lesion extent of resection (EOR) has been studied, existing analyses are limited by small samples and archaic data resulting in an inhomogeneous population. We investigated the relationship between EOR and survival outcomes, chiefly overall survival (OS) and progression-free survival (PFS), in a large contemporary cohort of spinal ependymoma patients. Methods Adult patients diagnosed with a spinal ependymoma from 200
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G, Manikantha, Hemant Muktaram Jawale, Akshat Awdhesh Kumar Mishra, Amarjeet E. Tandur, and Pratik J. Agrawal. "HYPOCHLOROUS ION BASED DRESSING: THROWBACK TO THE SURGEONS’ CHOICE." GLOBAL JOURNAL FOR RESEARCH ANALYSIS, April 15, 2021, 273–76. http://dx.doi.org/10.36106/gjra/6017724.

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1.1 BACKGROUND : As per Robbin's pathology(Robbins & Cotran Pathologic Basis of Disease - 10th Edition, n.d.) "an ulcer is the breach of the continuity of skin, epithelium or mucous membrane caused by sloughing out of inamed necrotic tissue." In an era of modern-day fast track surgery and premier practices of medicine, management of wound remains an archaic, almost omnipresent challenge to a health care provider mediating the need for solutions. The hunt for an optimum dressing agent has been everlasting, one of which is our point of discussion in this study. The addition of Chlorine(Cl2)
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Dr., Aayushi Pakhale, Alka Dive Dr., Archana Sonone Dr., Alka Hande Dr., Swati Patil Dr., and Rohit Mohril Dr. "Tongue as an identification tool in Forensic Odontology: Still a dilemma!" September 7, 2023. https://doi.org/10.5281/zenodo.8321388.

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<strong>Title*</strong> &nbsp; &ldquo;<strong>Tongue as an identification tool in Forensic Odontology: Still a dilemma!</strong>&rdquo; &nbsp; <strong>Author list and affiliations*</strong> &nbsp; <strong><sup>1</sup></strong><strong> Dr. Aayushi Pakhale</strong>, Assistant professor, Department of Oral &amp; Maxillofacial Pathology and Microbiology, &ldquo;Sharad Pawar Dental College &amp; Hospital&rdquo;, &ldquo;Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha&rdquo; - 442004, Maharashtra, India. Email id- pakhaleaayu@gmail.com&nbsp;&nbsp;&nbsp; 9561169929. Orc
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Dr., Aayushi Pakhale, Alka Dive Dr., Archana Sonone Dr., Alka Hande Dr., Swati Patil Dr., and Rohit Mohril Dr. ""Tongue as an identification tool in Forensic Odontology: Still a dilemma!"." September 7, 2023. https://doi.org/10.5281/zenodo.8324104.

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<strong>Title*</strong> &nbsp; &ldquo;<strong>Tongue as an identification tool in Forensic Odontology: Still a dilemma!</strong>&rdquo; &nbsp; <strong>Author list and affiliations*</strong> &nbsp; <strong><sup>1</sup></strong><strong> Dr. Aayushi Pakhale</strong>, Assistant professor, Department of Oral &amp; Maxillofacial Pathology and Microbiology, &ldquo;Sharad Pawar Dental College &amp; Hospital&rdquo;, &ldquo;Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha&rdquo; - 442004, Maharashtra, India. Email id- pakhaleaayu@gmail.com&nbsp;&nbsp;&nbsp; 9561169929. Orc
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