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1

Loosli, H. H., B. E. Lehmann, and W. Balderer. "Argon-39, argon-37 and krypton-85 isotopes in Stripa groundwaters." Geochimica et Cosmochimica Acta 53, no. 8 (August 1989): 1825–29. http://dx.doi.org/10.1016/0016-7037(89)90303-7.

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2

Abdurashitov, J. N., V. N. Gavrin, I. N. Mirmov, E. P. Veretenkin, V. E. Yants, N. N. Oshkanov, A. I. Karpenko, et al. "The New Status of Argon-37 Artificial Neutrino Source Project." Nuclear Physics B - Proceedings Supplements 110 (July 2002): 326–28. http://dx.doi.org/10.1016/s0920-5632(02)01499-8.

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3

Abdurashitov, J. "The new status of argon-37 artificial neutrino source project." Nuclear Physics B - Proceedings Supplements 110, no. 2 (July 2002): 326–28. http://dx.doi.org/10.1016/s0920-5632(02)80142-6.

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4

Mougenot, J., J. J. Gonzalez, P. Freton, and Y. Cressault. "Argon and Arcal.37 plasma characteristics in a TIG configuration." Journal of Physics D: Applied Physics 46, no. 49 (November 19, 2013): 495203. http://dx.doi.org/10.1088/0022-3727/46/49/495203.

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5

Riedmann, Robin A., and Roland Purtschert. "Separation of argon from environmental samples for Ar-37 and Ar-39 analyses." Separation and Purification Technology 170 (October 2016): 217–23. http://dx.doi.org/10.1016/j.seppur.2016.06.017.

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6

Fritz, B. G., ThomasR Alexander, TheodoreW Bowyer, JamesC Hayes, EmilyK Mace, and VincentT Woods. "Comparison of near-background concentrations of Argon-37 and Xenon-133 in the atmosphere." Journal of Environmental Radioactivity 233 (July 2021): 106590. http://dx.doi.org/10.1016/j.jenvrad.2021.106590.

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7

Zhou, Li, Yuetong Qian, Kang Gan, Hong Liu, Xiuju Liu, and Deli Niu. "Effect of different surface treatments and thermocycling on shear bond strength to polyetheretherketone." High Performance Polymers 29, no. 1 (July 28, 2016): 87–93. http://dx.doi.org/10.1177/0954008316628966.

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This study was designed to evaluate the shear bond strength of an adhesive/composite system subjected to different pretreated polyetheretherketone (PEEK) surfaces using different thermocycling conditioning methods. A total of 128 specimens were equally divided into four main groups ( n = 32/group): control (no pretreatment), air abrasion, argon plasma pretreatment, and femtosecond laser groups. The surface topographies and surface roughness were observed by atomic force microscopy after different pretreatments. The specimens were bonded with SE Bond/Clearfil AP-X™. All bonded specimens were stored in distilled water at 37°C for 24 h. Afterward, each group was divided into three subgroups ( n = 8/group) as follows: (a) stored in water for 56 h (37°C); (b) thermal aging for 5000 cycles (5°C/55°C); and (c) thermal aging for 10,000 cycles (5°C/55°C). The shear bond strengths were measured. Air abrasion, argon plasma pretreatment, and femtosecond laser significantly strengthened the bond of SE Bond/Clearfil AP-X™ to PEEK composite compared with that without additional pretreatment. In the same surface pretreatment, the shear bond strengths of specimens conditioned using water storage were higher than that using thermocycles (TCs). Additionally, the specimens with 5000 TC showed significantly higher shear bond strength than that with 10000 TC.
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8

Zhao, Hailin, Sian Mitchell, Stefania Koumpa, Yushi Tracy Cui, Qingquan Lian, Henrik Hagberg, Mark R. Johnson, Masao Takata, and Daqing Ma. "Heme Oxygenase-1 Mediates Neuroprotection Conferred by Argon in Combination with Hypothermia in Neonatal Hypoxia–Ischemia Brain Injury." Anesthesiology 125, no. 1 (July 1, 2016): 180–92. http://dx.doi.org/10.1097/aln.0000000000001128.

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Abstract Background Hypoxic–ischemic encephalopathy is a major cause of mortality and disability in the newborn. The authors investigated the protective effects of argon combined with hypothermia on neonatal rat hypoxic–ischemic brain injury. Methods In in vitro studies, rat cortical neuronal cell cultures were challenged by oxygen and glucose deprivation for 90 min and exposed to 70% Ar or N2 with 5% CO2 balanced with O2, at 33°C for 2 h. Neuronal phospho-Akt, heme oxygenase-1 and phospho-glycogen synthase kinase-3β expression, and cell death were assessed. In in vivo studies, neonatal rats were subjected to unilateral common carotid artery ligation followed by hypoxia (8% O2 balanced with N2 and CO2) for 90 min. They were exposed to 70% Ar or N2 balanced with oxygen at 33°, 35°, and 37°C for 2 h. Brain injury was assessed at 24 h or 4 weeks after treatment. Results In in vitro studies, argon–hypothermia treatment increased phospho-Akt and heme oxygenase-1 expression and significantly reduced the phospho-glycogen synthase kinase-3β Tyr-216 expression, cytochrome C release, and cell death in oxygen–glucose deprivation–exposed cortical neurons. In in vivo studies, argon–hypothermia treatment decreased hypoxia/ischemia-induced brain infarct size (n = 10) and both caspase-3 and nuclear factor-κB activation in the cortex and hippocampus. It also reduced hippocampal astrocyte activation and proliferation. Inhibition of phosphoinositide-3-kinase (PI3K)/Akt pathway through LY294002 attenuated cerebral protection conferred by argon–hypothermia treatment (n = 8). Conclusion Argon combined with hypothermia provides neuroprotection against cerebral hypoxia–ischemia damage in neonatal rats, which could serve as a new therapeutic strategy against hypoxic–ischemic encephalopathy.
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Alexander, T. R., C. E. Aalseth, H. O. Back, T. W. Bowyer, A. R. Day, E. S. Fuller, J. C. Hayes, et al. "Characterization of a low background proportional counter for a high throughput Argon-37 collection and measurement system." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 954 (February 2020): 161794. http://dx.doi.org/10.1016/j.nima.2019.01.021.

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10

Tkachuk, O. L., R. L. Parakhoniak, S. A. Plaksin, A. S. Glushenkov, and M. V. Fadeeva. "ARGON APPLICATION FOR CREATION OF PNEUMOPERITONEUM IN LAPAROSCOPIC SURGERIES." Novosti Khirurgii 29, no. 2 (April 21, 2021): 167–74. http://dx.doi.org/10.18484/2305-0047.2021.2.167.

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Objective. To advance the patients’ rehabilitation after laparoscopic surgeries by using insufflation with argon gas for pneumoperitoneum formation. Methods. The given study is the investigation of sequentially admitted 360patients with gallstone disease (cholelithiasis). The patients have been randomly divided into 4 groups: Group1 - uncomplicated gallstone disease, carboxyperitoneum (n=192); Group1a - acute cholelithiasis (n=37), carboxyperitoneum; Group2 - uncomplicated gallstone disease, argonperitoneum (n=102); Group2a - acute cholelithiasis (n=29), argonoperitoneum. All the patients have undergone laparoscopic cholecystectomies. Subjective assessment of the pain syndrome intensity has been studied on the basis of patient-reported outcomes questionnaire according to the visual analogue scale (VAS), need for analgesic injections, presence and intensity of the shoulder pain syndrome as well as the duration of in-patient treatment. Results. In accordance with patient-reported outcomes (with argonperitoneum application) subjective pain sensation has proved to decrease by 1.5-2 fold. On the first day of the postoperative period both in uncomplicated gallstone disease and in acute cholelithiasis, argonperitoneum has statistically significantly reduced the need for analgesics. Pain in the shoulder girdle (omalgia) was observed in 48.9% of the patients having been applied carboxyperitoneum whereas it was noticed in only 5.3% of the patients having been applied argonperitoneum during the operation. Argonperitoneum application statistically significantly reduces in-patient treatment period by 30% (from 2.3 - to 1.6 days) in uncomplicated gallstone disease and by 23% (from 4.3 - to 3.3 days) in gallstone disease complicated by acute cholelithiasis. Conclusion. Application of argon for pneumoperitoneum formation in laparoscopic cholecystectomies reliably reduces pain syndrome intensity in the postoperative period. The number of postoperative omalgia cases is reduced by 42% in patients having undergone cholecystectomies with argonperitoneum application. Application of argonperitoneum in management of patients with cholelithiasis may reduce the hospitalization period by 25-30%. What this paper adds The effect of argon application as an insufflation gas in laparoscopic operations upon the intensity of the postoperative pain syndrome has been studied for the first time. Argonperitoneum application has been found to improve the postoperative course by reducing pain irritation. Argon application leads to reduce analgesics consumption.
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11

Tyselskyi, V. V., B. G. Bondarchuk, V. A. Hordovskyi, and A. B. Kebkalo. "Application of biological welding as a method of treatment of esophageal metaplasia." Klinicheskaia khirurgiia 87, no. 5-6 (July 24, 2020): 9–12. http://dx.doi.org/10.26779/2522-1396.2020.5-6.09.

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Objective. To estimate a high-frequency welding of the living tissues as a variant of treatment for the Barrett’s esophagus. Materials and metods. Retrospective analysis of the treatment results was conducted in 73 patients, suffering Barrett’s esophagus, in 36 of whom the argon-plasm coagulation was performed (Group I), while in 37 (Group II) - a high frequency welding of living tissues. Into the investigation the patients with a short-segment Barrett’s esophagus C2-3M3-4 (the Prague Classification, 2004 yr) and a high-grade dysplasia without a nodule development (VI World Congress of International Society for Diseases of the Esophagus (ISDE) were included. Results. In patients of Group I a severe esophageal edema have occurred in accordance to endoscopic ultrasonography data. In this Group in 5 (13.89%) patients after performance of the argon-plasm coagulation esophageal stenosis was observed, corrected by application of the balloon dilation. In 8 (22.22%) patients of this Group the disease recurrence have occurred, necessitating performance of additional séance of the argon-plasm coagulation. In patients of Group II the above mentioned inflammatory signs were less pronounced, and mucosal regeneration have proceeded more rapidly, than in patients of Group I - during 53 and 115 days, accordingly. The disease recurrence was noted in 2 (5.41%) patients of Group II only. Conclusion. High-frequency welding of living tissues constitute a safe and effective method of treatment in patients, having esophageal metaplasia.
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12

Petrukhina, Daria, Irina Polyakova, and Sergei Gorbatov. "Biocide Effect of Non-Thermal Atmospheric Pressure Plasma." Food Processing: Techniques and Technology 51, no. 1 (March 25, 2021): 86–97. http://dx.doi.org/10.21603/2074-9414-2021-1-86-97.

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Introduction. New methods of sterilization with non-thermal atmospheric pressure plasma remain an extremely relevant field of food science. The present research estimated the effect of non-thermal argon plasma on lactic acid bacteria obtained from walnuts. Study objects and method. The non-thermal argon plasma was generated by electrode discharge induced by a coaxial microwave plasmatron at atmospheric pressure. The discharge was generated in a special electrode construction. Its stability was achieved via low gas flow through the discharge gap. Argon consumption was 10 L/min. The study involved Lactobacillus plantarum and Lactobacillus mali in their natural association and vegetative form. Endo’s medium (Endo agar) was inoculated with lactobacilli. 100 μl of the suspension were added into a Petri dish with nutrient medium and carefully rubbed with a spreader. The plates with Endo agar inoculated with lactobacilli were placed under plasma radiation at a distance of 45 mm. The biocidal effect of plasma radiation was estimated by the diameter of the affected areas. After the plasma treatment, the Petri dishes were incubated in an incubator for 24–48 h at 37°C, after which the diameters of the affected areas were measured again. Results and discussion. The paper introduces experimental data on the effect of argon plasma on lactobacilli isolated from food. After treating the surface of inoculated Petri dishes with non-thermal plasma for five minutes, the diameter of the inhibition zone reached the diameter of a Petri dish (80 mm) and exceeded the diameter of the spark gap of the plasma generator (36 mm). The temperature on the surface of the nutrient medium during plasma treatment was within the optimal temperature for lactobacillus growth, i.e. 37.3 ± 0.6°C, which excluded thermal effects. Only a few colonies survived a five-minute treatment. After one-minute treatment, the number of survived colony-forming units was considerably higher. Conclusion. Non-thermal argon plasma treatment proved effective in inhibiting the growth of gram-positive bacteria (Lactobacillus isolated from walnuts) on solid surfaces (agar plates). After five minutes of plasma treatment, the inactivated area (80 mm) exceeded the anode electrode cross section (36 mm) of the plasma generator.
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13

Surudzic, Rade, Sanja Erakovic, and Vesna Miskovic-Stankovic. "Synthesis and characterization of sintered hydroxyapatite/lignin coatings on titanium." Chemical Industry 66, no. 2 (2012): 187–92. http://dx.doi.org/10.2298/hemind110919086s.

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In order to improve corrosion stability and biocompatibility of titanium surfaces, hydroxyapatite (Ca10(PO4)6(OH)2, HAP) has been used as coating material due to the fact that it possess similar chemical composition as bone tissue. Lignin?s (Lig) usage in medical applications could be interesting because it could lead to thermal stability, hydrophilicity, biocompatibility and biodegradability of different materials. Bioceramic hydroxyapatite/lignin (HAP/Lig) coatings on titanium were obtained from ethanol suspension by electrophoretic deposition method. The uniform and compact HAP/Lig coatings were deposited at constant voltage of 60 V for 45 s and sintered at 900?C in argon atmosphere. The corrosion stability of sintered HAP/Lig coatings in simulated body fluid (SBF) at 37?C was investigated by open circuit potential-time measurements and electrochemical impedance spectroscopy (EIS). The greater values of open circuit potential, as well as EIS results, indicated improved corrosion resistance and good corrosion stability of HAP/Lig coatings in simulated body fluid at 37?C .
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Lima, Margarida Márcia Fernandes, Fillipe Valduga, and Rosa Malena Fernandes Lima. "Sintering of Manganese Ore Tailings under an Argon Atmosphere." Materials Science Forum 869 (August 2016): 1013–17. http://dx.doi.org/10.4028/www.scientific.net/msf.869.1013.

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Manganese is a chemical element widely used in Metallurgy. In Brazil, the ore’s beneficiation processes discharge the tailings (fraction size 0.106mm) with considerable Mn content. It would be interesting to recover this material. The aim of this work was to obtain and characterize the sinters from the manganese ore tailings at the Morro da Mina Mine. The fines (37 μm) were calcinated at 800°C for 3600s, and afterwards, homogenized with activated charcoal (7 and 10%) and CaO (5 and 10%). The sintering were carried out at 1135, 1140 and 1145°C during 7200 and 14400s under an argon atmosphere. The sintered products were characterized by BET surface area, apparent density, X-ray diffraction, MO and SEM/EDS. The presence of potassium from the alkalis justified the low melting point of the tailings (1145°C). Due to the chemical complexity of the tailings, several phases were identified in the products: pores, silicates with a high content of manganese in the matrix, as well as other silicates with different proportions of Al, Mn, Mg and Ca, pure Fe, and SiO2, etc.
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15

Nesmelov, D. D., A. S. Lysenkov, D. P. Danilovich, T. V. Kotsar', and S. S. Ordanian. "Collective synthesis of the CaB6‒TiB2 heterogeneous powders." NOVYE OGNEUPORY (NEW REFRACTORIES), no. 10 (December 29, 2018): 31–36. http://dx.doi.org/10.17073/1683-4518-2018-10-31-36.

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The heterogeneous CaB6‒TiB2powder blends were synthesized by means of the TiO2and CaCO3mixture boron carbide reduction under vacuum at 1400‒1650 °C, and reactive hot pressing was used according to the condition: 1500 °C (synthesis in vacuum) ‒ 1900 °C (Argon pressing). As a result of the CaB6‒TiB2synthesis with the mass ratio 1:1 at 1600 °C and isothermal time 1 hour the heterogeneous mixture was prepared which contained the CaB6and TiB2crystal phases as well as the residual B4C admixture (0,5 mass percent). The powder particles were the grains 1‒3 micrometers in diameter containing two phases CaB6and TiB2as the micro crystals 0,1‒1,0 micrometers in diameter uniformly spaced over the particle volume.Ill. 6. Ref. 37. Tab. 1.
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Radun, V., R. P. von Metzen, T. Stieglitz, V. Bucher, and A. Stett. "Evaluation of adhesion promoters for Parylene C on gold metallization." Current Directions in Biomedical Engineering 1, no. 1 (September 1, 2015): 493–97. http://dx.doi.org/10.1515/cdbme-2015-0118.

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AbstractDelamination of thin film polymeric coatings from metallization layers is a common cause of failure in biomedical implants. To address the problem, different adhesion promotion techniques can be applied which include surface pre-treatment with oxygen and argon plasma and the use of different adhesion promoters. In this paper the applicability of titanium (Ti), silicon oxide (SiOx), diamond-like carbon (DLC), tetramethylsilane (TMS) and aluminium oxide (AlOx) as adhesion promoters is evaluated. A cross cut, peel and scratch test are used to qualify and quantify the adhesion before and after storage in phosphate buffered saline (PBS) for 48 hours at a temperature of 37 °C. Promising results could be achieved by a combination of Ti and DLC as well as by AlOx.
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Golyanovskyy, O. V., О. O. Dyadyk, Y. V. Slobodian, K. S. Kozlova, and K. V. Stetsiuk. "Clinico-morphological features of the postoperative period and healing process of the uterine scar tissue after re-cesarean section." Reports of Vinnytsia National Medical University 22, no. 1 (August 8, 2018): 93–98. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(1)-18.

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A high number of repeat cesarean sections increases a risk of excessive bleeding, uterine atony, hysterectomy. The aim of study was to evaluate the efficacy of medical and technical methods (argon plasma coagulation, tranexamic acid, carbetocin) to prevent complications following repeat cesarean section and to improve the myometrial wound healing, to establish morphological features of uterine scar tissue in case of using argon plasma coagulation of myometrium in the area of the suture during the previous operation. Prospective cohort study of 77 patients who had undergone repeat cesarean section. I group included 37 women who had repeat cesarean section using argon plasma coagulation. Ten minutes before the operation, 15 mg/kg of tranexamic acid was injected intravenously. 100 mcg carbetocin was administered intravenously after cutting the umbilical cord. ІІ group comprised 40 women who had traditional cesarean section using Stark's technique and Joel-Cohen incision. Pathomorphological study of scarred lower uterine segment myometrium was performed. Immunohistochemical staining against CD3, CD34, CD68, vimentin, α-SMA was performed. Results are presented as Mean±SD. Total operative time was significantly shorter in the І group (37,0±2,1 minutes) compared to ІІ (46,1±1,8 minutes) (р<0,05). Volume of blood loss in the І group was 465,7±37,5 ml, and in the ІІ — 547, 7±34,6 ml (p<0.05). Patients of the І group needed analgesic for 18-24 hours, the ІІ group — 36-48 hours after operation. The width of the uterine cavity in group І was 9,8±0,37 mm, in group ІІ — 14,6±0,54 mm (р<0,05). One patient of group І and 9 patients of group ІІ had signs of uterine subinvolution. Length of hospital stay after surgery in group I was 4,7±0,12 days, in ІІ — 6,6±0,28 days. The ultrasound thickness of myometrium in group I and group II is an average of 9,32±0,64 mm and 6,24±0,59 mm, respectively. Pathomorphological data of scarred lower uterine segment myometrium showed that in group I regenerative processes have more favorable course, a tendency to restore the structure of myometrium, while in group II there were processes of disturbed regeneration with the replacement of smooth muscle tissue varying maturity of connective tissue, moderate inflammatory process. So, the use of tranexamic acid, carbetocin and argon plasma coagulation is effective in reducing perioperative blood loss, total operative time, dosage of uterotonic and analgesic medications and postoperative hospital stay in patients giving birth by repeat cesarean section. According to the pathomorphological study, argon plasma coagulation of myometrium in the area of suture increases the value of the reparative processes and promotes the formation of a morphologically complete scar, with the predominance of smooth muscle cells over connective tissue.
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18

Chung, Hsiu-Ying, J.-M. Yang, S. H. Tolbert, and R. B. Kaner. "Anisotropic mechanical properties of ultra-incompressible, hard osmium diboride." Journal of Materials Research 23, no. 6 (June 2008): 1797–801. http://dx.doi.org/10.1557/jmr.2008.0221.

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Borides of high electron density metals such as Os show promise as hard materials. Arc-melting elemental osmium and boron under an argon atmosphere produced osmium diboride (OsB2). Both a Vickers diamond microindenter and a Berkovich nanoindenter were used to measure hardness. Vickers microindentation indicates that the hardness of OsB2 increases significantly with decreasing applied load. The average hardness reaches approximately 37 GPa as the applied load is lowered to 0.245 N. The hardness is found to be highly dependent on the crystallographic orientation. For the {010} grains, along the 〈100〉 direction, the average hardness is significantly higher than that in the orthogonal 〈001〉 direction. Cracks associated with pop-in events in the nanoindentation load–displacement curves are observed in the {010} grains. The measured Young’s modulus of OsB2 is 410 ± 35 GPa, which is comparable to that obtained from first-principles calculations.
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Bestari, Muhammad Begawan, Ignatius Ronaldi Joewono, Dolvy Girawan, Jefry Tahari Argatio, and Siti Aminah Abdurachman. "Hemospray® during Emergency Endoscopy: Indonesia’s First Experience from 37 Patients." Case Reports in Gastroenterology 14, no. 1 (February 6, 2020): 70–79. http://dx.doi.org/10.1159/000505775.

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Gastrointestinal bleeding (GIB) is one of the main indications for performing endoscopy; this condition can be life threatening. In some cases, emergency endoscopy (EE) is necessary to identify the source and stop the bleeding. Recently, hemostatic powder was introduced, one of which was Hemospray® (Cook Medical, Winston-Salem, NC, USA), which showed promising results for rapid hemostasis in primary treatment and salvage when conventional methods fails. Samples were taken retrospectively for a duration of 3 years since Hemospray was first introduced in Indonesia, from January 2016 to January 2019. The total number of EEs that used Hemospray were 37 procedures for 37 patients; 21 (56.8%) were males and 16 (43.2%) were females, while the average age was 67.8 years. Hemospray was used for upper GIB in 30 cases (81.1%) and for lower GIB in 7 (18.9%). Hemospray was used as monotherapy for 24 patients (64.9%) and as secondary modality for 13 (35.1%). The primary treatment was argon plasma coagulation in 8 cases (21.6%), adrenaline in 4 (10.8%), and Histoacryl® in 1 (2.7%). The mortality rate was 37.8% (n = 14); most deaths occurred within 30 days after the EE was performed, and none of the deaths was related to endoscopy or GIB. Hemospray was able to achieve hemostasis in all cases. Furthermore, there was no event of rebleeding. When conventional modalities alone were inadequate, the combination with Hemospray appeared to be able to control the bleeding. One of the main advantages of Hemospray is the ease in reaching difficult areas, and it require less skill compared to conventional modalities.
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Phukaoluan, Aphinan, Anak Khantachawana, Pongpan Kaewtatip, and Surachai Dechkunakorn. "Assessment of Corrosion Behavior in Artificial Saliva of Wires for Orthodontic Applications." Materials Science Forum 917 (March 2018): 197–201. http://dx.doi.org/10.4028/www.scientific.net/msf.917.197.

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The aim of this study, the corrosion behavior of TiNiCu in artificial saliva (pH5.35) at 37°C was assessed by the use of electrochemical methods. Ti50Ni43Cu7 (at%) used in this study were made from ingots prepared by the vacuum arc melting (VAM) method. The furnace was purged with argon gas during melting. All melted ingots were then homogenized at 800°C for 3.6 ks. Open circuit potential (OCP) was monitored at 3.6 ks followed by potentiodynamic techniques. The results showed that all chemical composition of orthodontic wires by EPMA were Ti, Ni, Cu, Cr, Fe and Mn. Surface roughness was measured in order to ensure that TiNiCu and SS was significant difference which might affect corrosion resistance. It was seen that TiNiCu orthodontic wires, presented a good corrosion resistance, compared to the stainless steel, probably due to the formation of a protective oxide film mainly constituted by titanium oxide.
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Zammit, Stefania Chetcuti, Reena Sidhu, and David Sanders. "Refractory Anaemia Secondary to Small Bowel Angioectasias - Comparison between Endotherapy Alone versus Combination with Somatostatin Analogues." Journal of Gastrointestinal and Liver Diseases 26, no. 4 (December 1, 2017): 369–74. http://dx.doi.org/10.15403/jgld.2014.1121.264.zam.

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Background & Aims: Patients with small bowel angioectasias (SBAs) can be difficult to manage as they are generally elderly with multiple co-morbidities. Angioectasias are multiple and tend to recur. Argon plasma coagulation (APC), despite being a commonly used method to treat these patients has an associated persistent rate of re-bleeding necessitating additional treatment to manage these patients.Methods: All patients with refractory iron deficiency anaemia secondary to SBAs were retrospectively subdivided into two groups. Patients in group 1 were managed with double balloon enteroscopy (DBE) and APC alone and those in group 2 received Lanreotide in addition to DBE and APC.Results: A total of 49 patients were included in this study: group 1: 37 patients (75.5%), group 2: 12 patients (24.5%). All had significant comorbidities and the mean duration of anaemia was 114.3, SD 307.0 months. Significant improvements in haemoglobin (Hb) (11g/L vs 3.2g/L p=0.043), transfusion requirements per month (0.8 vs 4.7 p=0.052) and mean bleeding episodes (1.08 vs 2.6 p=0.032) were demonstrated in group 2 when compared to group 1. One patient developed symptomatic gallstone disease and one patient stopped Lanreotide due to a lack of response.Conclusions: This is the first study comparing endotherapy to a combination of endotherapy and pharmacotherapy. It shows a significantly better outcome in patients receiving a combination of endotherapy and Lanreotide. Lanreotide can be a safe additional treatment in patients not responding to APC alone.Abbreviations: APC: argon plasma coagulation; CE: capsule endoscopy; DBE double balloon enteroscopy; Hb: hemoglobin; OGIB: over gastrointestinal bleeding; SBAs: small bowel angioectasias.
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Basyir, Abdul, Didik Aryanto, Jayadi Jayadi, Wahyu Bambang Widayatno, and Agus Sukarto Wismogroho. "Karakterisasi Serbuk Timah dari Sistem Atomisasi Gas Argon Panas - Sub Sistem Gas Alir Tabung Gas." Jurnal Rekayasa Mesin 12, no. 1 (May 31, 2021): 181. http://dx.doi.org/10.21776/ub.jrm.2021.012.01.20.

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<p class="Abstract">The tin powder was used in some applications and technology such as for part manufacture through alloying, pressing, and sintering process, mixing material for the pyrotechnic application, the main material for solder pasta, mixing material on tin chemical, and others. Therefore, the demand for tin powder with a small size, spherical shape, and high purity is increasing severely. Indonesia (PT. Timah Tbk.) is one of the world’s largest producers of tin raw materials. This raw material can be processed be as powder by the atomization method. In this research, hot argon gas atomization system was used to generated tin powder. Raw tin was melted in a melting chamber with temperature variations of 600, 700, 800, and 900 °C. This experiment generates powder with a dominant size of 37 – 150 mm. Meanwhile, for size powder of 0 – 30 mm, dominated by size range of 0 – 10 mm. Furthermore, the size powder of 0 – 30 mm is composed of tin phase, without tin oxide. The tin powder of melting chamber temperature of 900 °C produces the largest tin powder with a size of 0 – 10 mm and spherical powder.</p>
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Kumaran, D., A. Rajadurai, and S. P. Sundar Singh Sivam. "An Investigation on the Suitability of Al-Mg Binary Hypo-Eutectic and Eutectic Aluminium Alloys as a Metal Matrix for Polymer Reinforced Composites and Lightweight Applications." Materials Science Forum 969 (August 2019): 484–89. http://dx.doi.org/10.4028/www.scientific.net/msf.969.484.

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This research work reports on the investigation on the suitability of prepared Al-Mg binary alloys of hypo-eutectic and eutectic compositions, for making metal matrix composites for light weight applications. Commercial pure aluminium, and magnesium blocks were used for the purpose of making binary alloys of Al-Mg, with the Mg in weight percentages 15%, 20%, 25%, 30%, and 37%. composition prepared by stir-casting under Argon cover gas. The cast Al-Mg alloys were cut to standard specimens to investigate its microstructure and mechanical properties. Test results revealed that the Vicker’s Hardness Number (VHN) of the alloys increases with the increased weight percentage of Mg and Ultimate Tensile Strength (UTS) were also increasing with increasing Mg content. The SEM images revealed the presence of micro-voids in alloys of higher Mg contents. The test values indicates the suitability of hypo-eutectic alloys as candidates for metal matrix composites for light weight applications.
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24

Islam, Rokibul, Shuzheng Xie, William Lekobou, Karl Englund, and Patrick Pedrow. "Surface modifications of wood materials using atmospheric pressure corona-based weakly ionized plasma." Journal of Thermoplastic Composite Materials 31, no. 7 (September 5, 2017): 946–58. http://dx.doi.org/10.1177/0892705717729019.

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Enhanced atmospheric pressure corona-based weakly ionized plasma was investigated to modify surface properties of wood materials. The plasma was generated using a point-to-point bare electrode geometry without dielectric barriers. The gas-phase admixture used in this work was argon and acetylene. Wood fibers were processed in the post-discharge region outside of the harsh corona environment. Return corona emanating into the high-voltage gap from the grounded screen was utilized to effectively activate acetylene molecules near the substrate. Scanning electron microscopy was used to study the surface morphology of the treated and untreated substrates. The treated wood material was observed to contain on their surface nano- and micro-nodules of plasma-polymerized acetylene. Capillary rise measurements confirmed changes in the surface wettability of the substrates. The water capillary rise rate and diffusion coefficient were reduced by about 37% and 57%, respectively, for a 15-min treatment of ponderosa pine wood flour.
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25

Al Gizawy, Samy M., Laila Abdelbaki, and Nahed A. Makhlouf. "Radiation induced-late bowel toxicity: role of argon plasma coagulation." Journal of Radiotherapy in Practice 11, no. 2 (August 5, 2011): 92–100. http://dx.doi.org/10.1017/s1460396911000112.

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AbstractPurpose: The purpose of this study was to identify predictors and treatment outcome of late bowel toxicity after three dimensional pelvic radiotherapy for genitourinary malignancies and also to describe our experience with Argon Plasma Coagulation (APC) in this toxicity.Patients and methods: Between March 2004 and March 2010, all patients who had completed a course of pelvic radiotherapy for genitourinary malignancies at our Institute were enrolled in this study. Every patient with lower GI symptoms underwent sigmoidoscopy and accordingly, some patients were subjected to intervention by APC.Results: One hundred and thirty-six patients met all inclusion criteria. Median FU period was 37 months. Chronic diarrhoea was scored as Grade 1 or 2 in 35 patients (25.7%). Chronic proctitis was scored as Grade 1 or 2 in 17 patients (12.5%) and Grade 3 in 6 patients (4.4%), 25 patients developed chronic bleeding per rectum, 16 (11.8%) were Grade 1 or 2, while 9 patients (6.6%) were Grade 3. Both maximum rectal dose and comorbidity ≥1 significantly correlated with the development of chronic proctitis (p = 0.040 for both).Endoscopic findings showed mucosal injury in 59 cases (84.29%) and vascular injury in 42 patients (60%). APC was successful in controlling bleeding and other symptoms in 14 cases (82.4%) and 16 cases (70%) respectively.Conclusion: Three dimensional pelvic radiotherapy using two-phase technique is associated with a low level of Grade 3 late lower gastrointestinal toxicities. The most common presenting symptom is chronic diarrhoea. Both maximum rectal dose and comorbidity ≥1 significantly predict the development of chronic proctitis. APC is an effective, safe and well-tolerated treatment for chronic radiation proctitis.
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26

Satapathy, Mantosh Kumar, Wei-Hung Chiang, Er-Yuan Chuang, Chih-Hwa Chen, Jia-Liang Liao, and Huin-Ning Huang. "Microplasma-assisted hydrogel fabrication: A novel method for gelatin-graphene oxide nano composite hydrogel synthesis for biomedical application." PeerJ 5 (June 27, 2017): e3498. http://dx.doi.org/10.7717/peerj.3498.

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Toxicity issues and biocompatibility concerns with traditional classical chemical cross-linking processes prevent them from being universal approaches for hydrogel fabrication for tissue engineering. Physical cross-linking methods are non-toxic and widely used to obtain cross-linked polymers in a tunable manner. Therefore, in the current study, argon micro-plasma was introduced as a neutral energy source for cross-linking in fabrication of the desired gelatin-graphene oxide (gel-GO) nanocomposite hydrogel scaffolds. Argon microplasma was used to treat purified gelatin (8% w/v) containing 0.1∼1 wt% of high-functionality nano-graphene oxide (GO). Optimized plasma conditions (2,500 V and 8.7 mA) for 15 min with a gas flow rate of 100 standard cm3/min was found to be most suitable for producing the gel-GO nanocomposite hydrogels. The developed hydrogel was characterized by the degree of cross-linking, FTIR spectroscopy, SEM, confocal microscopy, swelling behavior, contact angle measurement, and rheology. The cell viability was examined by an MTT assay and a live/dead assay. The pore size of the hydrogel was found to be 287 ± 27 µm with a contact angle of 78° ± 3.7°. Rheological data revealed improved storage as well as a loss modulus of up to 50% with tunable viscoelasticity, gel strength, and mechanical properties at 37 °C temperature in the microplasma-treated groups. The swelling behavior demonstrated a better water-holding capacity of the gel-GO hydrogels for cell growth and proliferation. Results of the MTT assay, microscopy, and live/dead assay exhibited better cell viability at 1% (w/w) of high-functionality GO in gelatin. The highlight of the present study is the first successful attempt of microplasma-assisted gelatin-GO nano composite hydrogel fabrication that offers great promise and optimism for further biomedical tissue engineering applications.
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Obagi, Suzan, Zein E. Obagi, and James B. Bridenstine. "Isotretinoin Use during Chemical Skin Resurfacing: A Review of Complications." American Journal of Cosmetic Surgery 19, no. 1 (March 2002): 9–13. http://dx.doi.org/10.1177/074880680201900103.

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Introduction: There is a great deal of concern when it comes to resurfacing the skin of patients who have recently taken or are taking isotretinoin. Much of the concern arises from reports of abnormal and keloidal scarring postdermabrasion, Argon laser, and pulsed dye laser. This study was designed to retrospectively evaluate the complication rate of patients undergoing chemical resurfacing within 2 years of taking isotretinoin and to see if timing of the medication and depth of peel correlated. Materials and Methods: This is a retrospective chart review of 91 patients (14 men, 77 women) who had 123 peels documented. Patients were assigned to 1 of the following 4 groups based on the timing of isotretinoin use to the chemical peel: prepeel, perioperative, pre- and postpeel, and postoperative. Complications, isotretinoin dose, patient age and race, peel depth, and presence of keloids before surgery were recorded. Results: A total of 123 peels were documented in 91 patients: 51 prepeel, 13 perioperative, 22 pre- and postpeel, and 37 postoperative. The complications recorded were prolonged erythema (0.8%), atrophic scarring (0.8%), altered texture (0.8%), delayed healing (3.25%), and hypertrophic scarring (2.44%). Delayed healing was observed only in patients taking isotretinoin before or at the time of surgery. Two of 3 patients who developed hypertrophic scarring had taken isotretinoin during the postoperative stage. Discussion: Although previous case reports suggest a correlation between isotretinoin use and abnormal or keloidal scarring after dermabrasion, Argon laser, and pulsed dye laser, the occurrence of hypertrophic scarring remained low in the chemical-peel group of patients. We suggest avoiding isotretinoin for 3 months preoperatively and delaying postoperative use of isotretinoin until dermal regeneration is complete (3 months). Further studies are needed to determine if the use of refrigerants in dermabrasion and the heat generated by lasers cause temperature alterations that predispose to scarring in patients taking isotretinoin.
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Makridis, Sofoklis S. "Structural and Magnetic Properties of Sm(CobalFe0.1Ni0.12Zr0.04B0.04)7.5 Melt Spun Ribbons." Materials Science Forum 636-637 (January 2010): 404–10. http://dx.doi.org/10.4028/www.scientific.net/msf.636-637.404.

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We have investigated the structural and magnetic properties of Sm(Co0.70Fe0.1Ni0.12Zr0.04B0.04)7.5 melt spun ribbons. The arc-melted bulk samples have been used to obtain ribbons at 37 up to 55 m/sec while annealing has been performed in argon atmosphere for 30-75 min at 600-870 oC. In as-spun ribbons the hexagonal SmCo7 (TbCu7-type of structure) of crystal structure has been determined from x-ray diffraction patterns, while fcc-Co has been identified as a secondary phase. After annealing, the 1:7 phase of the as-spun ribbons transforms into 2:17 and 1:5 phases. TEM analysis shows a homogeneous nanocrystalline microstructure with average grain size of 30-80 nm. Coercivity values of 15-27 kOe are obtained from hysteresis loops traced at non-saturating fields. The coercivity decreases as temperature increases, but it is high enough to maintain values higher than 5 kOe at 380 oC. The maximum energy product at room temperature increases, as high as 7.2 MGOe, for melt-spun ribbons produced at higher wheel speed.
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29

Hollenbach, Marcus, Lars Selig, Sylvia Lellwitz, Sebastian Beer, Jürgen Feisthammel, Jonas Rosendahl, Tiffany Schaumburg, Joachim Mössner, and Albrecht Hoffmeister. "Endoscopic full-thickness transoral outlet reduction with semicircumferential endoscopic submucosal dissection." Endoscopy 51, no. 07 (April 15, 2019): 684–88. http://dx.doi.org/10.1055/a-0866-9427.

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Abstract Background Endoscopic full-thickness transoral outlet reduction (efTOR) is a therapeutic option to reduce a dilated gastrojejunal anastomosis (GJA) after Roux-en-Y gastric bypass (RYGB). Mucosal ablation with argon plasma coagulation (APC) is usually performed to achieve tissue adaptation. However, rupture of sutures before scarring can lead to recurrent dilatation of the GJA. Here, we describe efTOR with a semicircumferential endoscopic submucosal dissection (ESD-efTOR) as an alternative to APC-efTOR. Methods We enrolled 41 patients with comparable baseline characteristics (APC-efTOR 26; ESD-efTOR 15). The main objectives were reduction in the GJA diameter and in ruptured sutures. Technical success, complications, total weight loss (TWL), and percentage of total and excess weight loss (%TWL and %EWL) at 3 and 12 months, were assessed. Results ESD-efTOR resulted in significantly fewer ruptured sutures (20 % vs. 69 %; P = 0.004) and a greater reduction in the GJA (major 20 % vs. 0 %; minor 54 % vs. 37 %; no reduction 13 % vs. 58 %; P = 0.02) after 3 months. Technical efficacy, examination time, and rate of complications were comparable. Conclusions ESD-efTOR resulted in a significantly greater reduction in the GJA diameter and a lower risk of ruptured sutures compared with APC-efTOR.
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Ayres, APA, R. Hirata, BM Fronza, BB Lopes, GMB Ambrosano, and M. Giannini. "Effect of Argon Plasma Surface Treatment on Bond Strength of Resin Composite Repair." Operative Dentistry 44, no. 2 (March 1, 2019): E75—E82. http://dx.doi.org/10.2341/18-050-l.

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SUMMARY Objectives: This study evaluated the effect of argon plasma treatment (PLA) and its combination with sandblasting (SAN), silanization (SIL), and hydrophobic bonding resin (HBR) application on the micro-shear bond strength of water-aged restorative resin composite to a newly placed composite, simulating restoration repair. Methods and Materials: Forty-five light-cured composite plates (20-mm long × 20-mm wide × 4-mm thick) were fabricated using a hybrid composite and stored at 37°C in distilled water for six months. The aged composite surfaces were treated according to the following experimental groups, varying both treatment and order of application: 1) SAN + SIL + HBR (control), 2) SAN + PLA for 30 seconds + SIL + HBR, 3) SAN + SIL + PLA + HBR, 4) PLA + SIL + HBR, 5) PLA + SIL, 6) PLA + HBR, 7) SIL + PLA + HBR, 8) SIL + PLA, and 9) PLA. After the surface treatments, four fresh resin composite cylinders (1.5-mm high × 1.5-mm diameter) of the same composite were built on each aged composite surface using a silicone mold. After water storage for 24 hours or one year, the specimens were submitted to shear bond strength testing. Data were statistically analyzed by two-way analysis of variance and Tukey's test (5%). Results: Groups 1, 2, and 4 presented significantly higher bond strength means at 24 hours, although group 4 did not differ from group 7. Groups 5, 8, and 9 demonstrated significantly lower means than the other groups. Even though groups 1 and 2 had a significant bond strength reduction after 1 year, they still demonstrated higher bond strength at one year of storage. Conclusions: While PLA application combined with surface treatment methods demonstrated high bond strength results, this treatment alone was not as beneficial as other methods that included SAN, SIL and HBR.
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Arab Pour Yazdi, Mohammad, Nicolas Martin, Christian Petitot, Khalid Neffaa, Frank Palmino, Frederic Cherioux, and Alain Billard. "Influence of Sputtering Parameters on Structural, Electrical and Thermoelectric Properties of Mg–Si Coatings." Coatings 8, no. 11 (October 25, 2018): 380. http://dx.doi.org/10.3390/coatings8110380.

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Mg–Si thin films (23 ≤ at.% Si ≤ 43) were deposited by co-sputtering of Mg and Si targets in an argon atmosphere. Two groups of samples were prepared with respect to sputtering parameters. The first Group I was synthesized while residual pressure in the reactor was lower than 7 × 10−4 Pa and the second Group II when reactor was pumped down to pressure higher than 7 × 10−4 Pa. The Mg2Si phase appeared for all as-deposited films of Group I around the stoichiometric composition region (29 ≤ at.% Si ≤ 37) and in the Mg-rich region (at.% Si < 29) the Mg2Si and Mg phases coexisted. An amorphous structure was obtained for all as-deposited films of Group II no matter their composition (34 ≤ at.% Si ≤ 38) and the Mg2Si structure was achieved after post annealing under air at temperature ≥140 °C. Thermal stability of Mg2Si thin films was investigated by annealing treatments under air. Superficial Mg2Si structural decomposition began at T > 500 °C and layer morphology and structure damaged while annealing temperature increased up to 700 °C. The films’ electrical resistivity, free carrier concentration and mobility as well as Seebeck coefficient were measured and thermoelectric power factors were discussed vs. composition.
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32

Zádorová, Zdena, Jan Hajer, and Václav Mandys. "Multiple Adenomatous Duodenal Polyposis." Case Reports in Gastrointestinal Medicine 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/181704.

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Multiple duodenal polyps are a relatively rare finding, usually co-occurrent with familial adenomatous polyposis (FAP).We report a patient with multiple duodenal adenomas and a negative examination for FAP: multiple flat polyps were detected endoscopically in a 37-year-old male patient, extending from the apex of the bulb to the end of the descending part of the duodenum. In terms of histology, they were tubular adenomas with moderate dysplasia. Colonoscopy and enteroclysis were normal. Both push and capsule enteroscopy only showed multiple polyps in the area of the descending duodenum. DNA analysis of the APC gene was as follows: DGGE, exon 1–15, deletion at codons 1309 and 1061 by means of PCR for attenuated APC were negative. Afterwards we screened the patient for germline MYH mutations using the denaturing high-performance liquid chromatography (DHPLC) in combination with sequencing. No novel pathogenic mutation has been identified. Large polyps were removed by means of endoscopic polypectomy and mucosectomy, while small polyps were removed by means of argon plasma coagulation.We conduct yearly checkups, removing only sporadic polyps. The rare finding of duodenal polyposis not co-occurrent with FAP proves that multiple adenomas in the digestive tube need not necessarily co-occur with FAP.
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33

Sahlberg, Anna-Lena, Dina Hot, Rasmus Lyngbye-Pedersen, Jianfeng Zhou, Marcus Aldén, and Zhongshan Li. "Mid-Infrared Polarization Spectroscopy Measurements of Species Concentrations and Temperature in a Low-Pressure Flame." Applied Spectroscopy 73, no. 6 (March 27, 2019): 653–64. http://dx.doi.org/10.1177/0003702818823239.

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We demonstrate quantitative measurements of methane (CH4) mole fractions in a low-pressure fuel-rich premixed dimethyl ether/oxygen/argon flat flame (Φ = 1.87, 37 mbar) using mid-infrared (IR) polarization spectroscopy (IRPS). Non-intrusive in situ detection of CH4, acetylene (C2H2), and ethane (C2H6) in the flame was realized by probing the fundamental asymmetric C–H stretching vibration bands in the respective molecules in the spectral range 2970–3340 cm−1. The flame was stabilized on a McKenna-type porous plug burner hosted in a low-pressure chamber. The temperature at different heights above the burner (HAB) was measured from the line ratio of temperature-sensitive H2O spectral lines recorded using IRPS. Quantitative measurements of CH4 mole fractions at different HAB in the flame were realized by a calibration measurement in a low-pressure gas flow of N2 with a small admixture of known amount of CH4. A comprehensive study of the collision effects on the IRPS signal was performed in order to quantify the flame measurement. The concentration and temperature measurements were found to agree reasonably well with simulations using Chemkin. These measurements prove the potential of IRPS as a sensitive, non-intrusive, in situ technique in low pressure flames.
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34

Fijołek, Andrzej, Janusz Lelito, Halina Krawiec, Jagoda Ryba, and Łukasz Rogal. "Corrosion Resistance of Mg72Zn24Ca4 and Zn87Mg9Ca4 Alloys for Application in Medicine." Materials 13, no. 16 (August 9, 2020): 3515. http://dx.doi.org/10.3390/ma13163515.

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The aim of this work was to monitor the corrosion rate of the Mg72Zn24Ca4 and Zn87Mg9Ca4 alloys. The purity of the alloying elements was 99.9%. The melt process was carried out in an induction furnace. The melting process took place under the cover of an inert gas (argon). The copper form was flooded by liquid alloy. Then, in order to obtain ribbons, the cast alloy, in rod shape, was re-melted on the melt spinning machine. The corrosion resistance of both alloys has been determined on the basis of the following experiments: measurements of the evolution of OCP (open circuit potential), LSV (linear sweep voltamperometry) and EIS (electrochemical impedance spectroscopy). All corrosion tests were carried out in Ringer’s solution at 37 °C and pH 7.2. The corrosion tests have revealed that the zinc alloy, Zn87Mg9Ca4, exhibits significantly higher corrosion resistance in the Ringer solution compared to the magnesium alloy, Mg72Zn24Ca4. Moreover, it has been shown that the cathodic reaction proceeds faster on the surface of ribbons. EIS measurements show that the dissolution of Mg alloy proceeds with two steps: transfer of Mg2+ ions to the Ringer solution and then the formation of the corrosion products, which are deposited on the surface of magnesium alloy. It has been revealed, too, that for both bulk materials, diffusion of chloride ions through the corrosion product’s layer takes place.
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35

Qu, Tianpeng, Caiwei Zhang, Deyong Wang, Jie Zhan, Jun Tian, and Dong Hou. "Effect of Mg–Ti Treatment on Nucleation Mechanism of TiN Inclusions and Ferrite." Metals 10, no. 6 (June 5, 2020): 755. http://dx.doi.org/10.3390/met10060755.

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Large sizes of columnar crystals and TiN particles have a great influence on the surface quality of ferritic stainless steel. In the present paper, this study proposed to obtain fine-grained equiaxed structures by Mg–Ti treatment. Through the experiment happened in resistance furnace with argon protection, the refining effect of Mg–Ti addition on the microstructure and TiN particles were investigated, and the refinement mechanism was discussed from interface coherence theory. It was found that due to adding Mg and Ti into molten ferritic stainless steel, the equiaxed crystal ratio increased from 37% to 50%, and the size of TiN particles reduced at the same time. The lattice matching characteristics of MgAl2O4/TiN and TiN/δ-Fe were investigated by FIB-HRTEM. According to Bramfitt’s equation, the lattice misfit for (400)MgAl2O4∥(200)TiN and (200)TiN∥(110)δ-Fe was 5.02% and 4.41%, respectively, which were all belong to the effective nucleation range. It could be considered that MgO and MgAl2O4 formed in the molten steel promoted TiN nucleation easier to precipitate out with large quantities in the liquid phase. The TiN particles with more uniform distribution significantly enhanced the heterogenous nucleation of ferritic phase during initial solidification process base on the good lattice fitting condition. Finally the equiaxed crystal ratio of δ-Fe phase increased dramatically.
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36

Tseng, Lin Yung, Jhewn Kuang Chen, Kai Hung Hsu, Wan Yu Wu, and Chi Lung Chang. "Microstructure and Mechanical Properties of Cr-W-B-N Coating Deposited by DC Reactive Magnetron Co-Sputtering." Advanced Materials Research 651 (January 2013): 430–35. http://dx.doi.org/10.4028/www.scientific.net/amr.651.430.

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Nanocomposite Cr-W-B-N coatings with various tungsten contents were synthesized on silicon wafer substrates. The used technique is a DC reactive magnetron co-sputtering deposition equipped with a Cr-B alloy target with 20 at.% B and a W target in a mixed argon/nitrogen plasma atmosphere. Composition and microstructure of the obtained coatings were investigated using X-ray diffraction, X-ray Photoelectron Spectroscope and transmission electron microscope while the micro-hardness was measured using a depth-sensing nano-indenter. The results have shown that the microstructure and the mechanical properties of Cr-W-B-N coatings were strongly dependent on either the tungsten content or the volume fraction of W-N crystalline phases. It was observed that the micro-hardness of Cr-W-B-N coatings is lower than that of Cr-B-N coating as the tungsten content is less than 24 at.% and the volume fraction of W-N crystalline phases is lower than 37 vol.%. As the tungsten content further increased to 30 at.% and the volume fraction of W-N crystalline phases increased to 55 vol.%, the micro-hardness of Cr-W-B-N coating was found enhanced to 19 GPa and higher than Cr-B-N film. It was also obtained that the volume fraction of Cr-N crystalline phases is inversely proportional to the volume fraction of W-N crystalline phases.
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37

Cherednikov, Evgeniy, Sergey Barannikov, Igor Yuzefovich, Galina Polubkova, Yuri Maleev, Irina Volkova, Anastasiya Vysotskaya, Oleg Strygin, and Evgeniy Ovsyannikov. "Innovative Endoscopic Technologies in the Complex Treatment of Patients with Unstable Stopped Gastroduodenal Bleeding." International Journal of Biomedicine 11, no. 1 (March 5, 2021): 24–28. http://dx.doi.org/10.21103/article11(1)_oa4.

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Background: The aim of our research was to improve the results of treatment of patients with unstable bleeding gastroduodenal ulcers (GDUs) through the use of innovative endoscopic technologies in the complex treatment of gastroduodenal bleeding (GDB). Methods and results: The study included 132 patients with unstable ulcerative GDB. Among all patients with GDB, there were 95(71.96%) men and 37(28.04%) women. The average age of patients was 56.1±18.45 years. Among the sources of gastroduodenal ulcer bleeding, duodenal ulcers complicated by bleeding predominated were observed in 77(58.3%) patients, bleeding gastric ulcers and ulcers of gastroenteroanastomosis areas in 49(37.7%) and 6(4.6%) patients, respectively. According to the endoscopic classification (J. Forrest, 1974), continued bleeding (Forrest Ia-Ib) was observed in 44(33.3%) patients, threat of rebleeding (Forrest IIa-IIb) in 88(66.7%) patients. All patients were divided, by random sampling, into two equivalent groups: the main group (MG, n=66) and the comparison group (CG, n=66). In the treatment of MG patients, an individual approach was applied that used the injection of ε-aminocaproic acid, argon-plasma coagulation, and the endoscopic pneumatic applications of hemostatic agents (Zhelplastan and the patient's platelet-rich auto-plasma) and granular sorbents (Aseptisorb-A, Aseptisorb-D). In CG, traditional methods of endoscopic hemostasis (injection method with ε-aminocaproic acid and vasoconstrictor drugs, argon plasma coagulation, etc.) were used without granular sorbents and innovative hemostatic agents. In patients with the Forrest Ia-Ib bleeding, primary EH was achieved in 95.2% of cases in the MG and in 91.3% of cases in the CG (P>0.05). In patients with the Forrest IIa-IIb bleeding, effectiveness of endoscopic prevention of recurrent bleeding was achieved in 95.5% of cases in the MG and in 81.4% of cases in the CG (P=0.047). Mortality rate was 1.5% in the MG and 4.5% in the CG (P>0.05). In the MG and CG, the overall frequency of recurrent bleeding from GDUs, the operational activity, and the length of hospital stay were 15.2% and 4.5% (P=0.041), 12.1% and 1.5% (P=0.033), and 11.1±0.6 days and 9.2±0.4 days (P<0.01), respectively. Conclusion: The developed method for the complex treatment of patients with unstable GDB, based on the optimization of emergency and preventive endoscopic hemostasis, indicates that the use of therapeutic endoscopy to prevent bleeding recurrences with hemostatic agents and granular sorbents improves the reliability of endoscopic hemostasis, reduces the frequency of hemorrhage relapses and the number of emergency operations, as well as a length of hospital stay.
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38

Amaro-Villeda, Adrián M., A. Conejo, and Marco A. Ramírez-Argáez. "Effect of Slag on Mixing Time in Gas-Stirred Ladles Assisted with a Physical Model." MRS Proceedings 1485 (2012): 101–6. http://dx.doi.org/10.1557/opl.2013.256.

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ABSTRACTA 1/6th water physical model of a 140 tons gas-stirred steel ladle is used to evaluate mixing times (τm at 95% of chemical uniformity) in a two phase system without slag (air-water) and in a more realistic three phase system (air-water-oil) to simulate the argon-steel-slag system and quantify the effect of the slag layer on the mixing time. Slag layer is kept constant at 0.004 m. Mixing times are estimated through measured changes in pH due to the addition of a tracer (NaOH 1 M). The effect of the following variables on the mixing time is evaluated for a single injector: gas flow rate (7, 17 y 37 l/min) and the injector position (R/r= 0, 1/3, ½, 2/3 and 4/5). Experimental results obtained in this work show good agreement when compared against mixing time correlations reported by Mazumdar for the two phase air-water case (no slag considered). Another comparison is done using the new concept called “effective bath height” proposed by Barati, where the mixing time is a function of the size of the slag layer since this layer dissipates part of the total amount of stirring energy introduced into the ladle by the injection of gas. Agreement is not good in this case. Finally, an estimation of the percentage of the stirring energy dissipated by the slag is computed, including other factors that govern the dissipation of stirring energy. Percentage of energy dissipated by the slag is found to be between 2.7 to 12 % depending on the process conditions.
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39

Avcu, Ferit, Ali U. Ural, Yusuf Baran, Gungor Sobaci, Mustafa Deveci, Turker Cetin, Aysel Pekel, Meral Sarper, Pinar Elci, and Ufuk Gunduz. "A Photodynamic Pathway to Apoptosis Induced by Hypericin in Human Myeloma ARH-77 Cell Line: Possible Relevance to Photodynamic Therapy." Blood 106, no. 11 (November 16, 2005): 5076. http://dx.doi.org/10.1182/blood.v106.11.5076.5076.

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Abstract Hypericin, a photosensitizing plant pigment from Hypericum perforatum, is a protein tyrosine kinase inhibitor that has been exploited in models for anti-tumor and anti-viral activity. In this study, we investigated the effects of hypericin on the human myeloma cell line ARH-77 as a model to determine whether hypericin-induced cell death is available. The cells were incubated with hypericin at concentrations ranging from 0.001 to 10 microg/ml in RPMI at 37°C in 5% CO2 atmosphere for 4 h. Then, the cells were irradiated at 532 nm (fluence=24 J/cm2) using a dye laser pumped by an argon laser (Orion). After 72 h exposure, the IC50 of hypericin was 0.005 microg/ml as determined by the MTT assay. Hypericin exerted phototoxic effect on ARH-77 cells, while it did not produce toxic effect in the absence of irradiation. After 72 h exposure to 0.005 microg/ml photoactive hypericin, apoptosis was assessed by morphological changes, DNA fragmentation and flow cytometric analysis using Annexin V and propidium iodide staining. Most of the cells were accumulated in the late stage of apoptosis and these cells were brightly stained and fragmented nuclei and cytoplasmic blebbing were observed. A decrease in the number of apoptotic cells was detected when protein kinase C was inhibited by addition of staurosporine to photoactive hypericin induced ARH-77 cells. From these results, we demonstrated that exposing myeloma cell line ARH-77 to photoactive hypericin inhibits cell growth in a dose dependent manner, induces apoptotic cell death by protein kinase C activation, and provides a rationale for potential applications in vivo.
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40

Kaye, Andrew H., George Morstyn, and David Brownbill. "Adjuvant high-dose photoradiation therapy in the treatment of cerebral glioma: a Phase 1–2 study." Journal of Neurosurgery 67, no. 4 (October 1987): 500–505. http://dx.doi.org/10.3171/jns.1987.67.4.0500.

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✓ A Phase 1–2 study of high-dose photoradiation therapy was performed in 23 patients with cerebral tumors. Twenty-two patients had high-grade gliomas (13 glioblastomas, six recurrent glioblastomas, two anaplastic astrocytomas, and one recurrent anaplastic astrocytoma) and one had a right frontal metastasis from a carcinoma of the lung. Hematoporphyrin derivative was administered to these patients in a dose of 5 mg/kg and, 24 hours later, they all underwent a craniotomy with radical excision of the tumor. The tumor bed was then irradiated with 630 nm of laser light from either an argon dye laser or a gold metal vapor laser for between 43 and 94 minutes, receiving total doses of 70 to 120 J/sq cm (six cases) or 120 to 230 J/sq cm (17 cases). The temperature of the tumor bed was kept below 37°C by irrigation. Fifteen patients who developed new tumors underwent postoperative radiotherapy (45 Gy in 20 divided doses). There was no evidence of increased cerebral edema and no other toxicity from the therapy. All patients were discharged from the hospital within 18 days of surgery. Four of seven patients with gliomas have suffered a further recurrence at 12 to 16 weeks, and two of 15 patients with primarily treated gliomas experienced recurrence at 3 and 13 months following therapy. Fifteen patients have had no recurrence of their tumor and are alive and well at a median follow-up period of 7 months (range 1 to 16 months). It is concluded that photoradiation therapy using 5 mg/kg of hematoporphyrin derivative and 630 nm light at doses of up to 230 J/sq cm can be used as an adjuvant to surgery and radiotherapy with no additional complications.
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41

Marques, Margarida, João Santos-Antunes, Rosa Coelho, Hélder Cardoso, Filipe Vilas Boas, Armando Ribeiro, and Guilherme Macedo. "Single-balloon enteroscopy efficacy and degree of concordance with noninvasive evaluation of small bowel." Endoscopy International Open 05, no. 02 (February 2017): E96—E102. http://dx.doi.org/10.1055/s-0042-121415.

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Abstract Background and study aims Clinical impact of single-balloon enteroscopy (SBE) is fairly known, as well as its diagnostic yield comparing with other small bowel gastrointestinal investigations. This study represents a contribution to better understand it and is designed to evaluate SBE efficacy and degree of concordance with previous evaluation of small bowel. Patients and methods This is a single-center retrospective study of patients that underwent SBE with suspected small bowel disease based on non-invasive imaging. Demographic, clinical, procedural and outcome data were collected for analysis. Agreement beyond positive findings was evaluated using κ-coefficient. Results A total of 197 SBEs were performed in 168 patients; mainly men (64.3 %) with mean age 53.3±17.6 years. Most SBEs (86.3 %) performed were preceded by a noninvasive evaluation: in 61.4 % (n = 119) of cases, capsule enteroscopy (CE) was performed, in 18.8 % (n = 37), computed tomography was performed, and in 6.1 % (n = 12) magnetic resonance enterography was performed. Fourty-three patients (25.6 %) underwent endoscopic treatments, mainly: argon plasma coagulation in angioectasias (53.4 %) and polypectomy (34.9 %). The most common diagnoses made with SBE were findings consistent with inflammatory small bowel disease (21.8 %) and vascular lesions (14.2 %). The diagnostic yield of SBE was of 69 %, confirming the suspicion of small bowel disease. The degree of concordance between CE and SBE for positive findings was substantial, κ-coefficient = 0.635 (P < 0.001). However, the degree of concordance between imaging examinations (CT or MR) and SBE was only moderate, κ-coefficient = 0.410 (P < 0.001). SBE had an immediate effect in 20 % of patients, changing diagnostic approaches, medical and surgical treatments. Conclusions Our study supports the idea that for suspected small bowel disease, CE and SBE have an overall good degree of concordance for all the diagnostics included.
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42

Smetkin, A. A., S. A. Oglezneva, K. V. Kalinin, and E. F. Khanipov. "Structure and properties of corrosion-resistant steel obtained by selective laser melting." Izvestiya Vuzov. Poroshkovaya Metallurgiya i Funktsional’nye Pokrytiya (Universitiesʹ Proceedings. Powder Metallurgy аnd Functional Coatings), no. 1 (March 21, 2019): 91–97. http://dx.doi.org/10.17073/1997-308x-2019-1-91-97.

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The objects of study were stainless steel powder 12Kh18N10T of the 20–63 μm fraction and experimental samples obtained on the basis of it by selective laser melting (SLM). The powder was obtained by spraying with argon at a temperature of 1640 °C and a pressure of 27 bar. The particles have the dendritic-cellular structure, with a decrease in their size (<35 μm), the cellular structure prevails, and the dendritic one almost disappears. The distinctive particle size is d50 = 37 μm, d100 = 67 μm. The differential distribution curve is close to the Gaussian form, and asymmetry is associated with satellite and the presence of a small number of particles less than 20 microns in size. The fluidity of the powder was 3,27 g/s, and the bulk density was 4,41 g/cm3. The density of the 12Kh18N10T steel samples grown at the Concept Laser M2 facility with a laser power of 180 W and a speed of 700 mm/s averaged 7,89 g/cm3. Since the density of compact steel is 7,95 g/cm3, the obtained material has enough high density. The microstructure of the 12Kh18N10T sample was described by continuity, the absence of pores and cracks. It was a solid solution of austenite. The average size of coherent scattering regions in the grain volume was 19 nm. The observed arcuate boundaries of parallel semicircular tracks are due to heat removal during crystallization through SLM. The elongated crystallites in the tracks are oriented inward from this boundary. The microhardness of the samples in the transverse plane of the thin section is higher than the microhardness of the planar plane. But the microhardness of the samples obtained from the powder by the SLM is higher than that of the standard compact alloy. Tensile strength and elongation are 651 MPa and 47 %, respectively. The increase in strength is probably due to the grinding of structural parameters in SLM. The fracture surface of the samples is characterized by a pronounced viscous type.
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43

Liang, Jing. "Systematic review and meta-analysis of the negative outcomes of retinopathy of prematurity treated with laser photocoagulation." European Journal of Ophthalmology 29, no. 2 (July 19, 2018): 223–28. http://dx.doi.org/10.1177/1120672118770557.

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Introduction: Retinopathy of prematurity is a leading cause of potentially avertable childhood blindness around the world. And laser photocoagulation is currently performed as a gold standard for retinopathy of prematurity treatment, but it may contribute to elevated myopia and decreased visual field. Therefore, the objective of this meta-analysis is to explore the negative impact of laser photocoagulation for retinopathy of prematurity in terms of anatomic outcomes and structural outcomes. Methods: Studies were retrieved through literature searches in PubMed and EMBASE from 1990 to 2017 in English. Case-control studies that reported anatomic and structural changes or significant complications after laser coagulation or cryotherapy for retinopathy of prematurity were eligible. Results: This meta-analysis included eight original studies related to laser treatment for retinopathy of prematurity at any stages. A total of 1422 infants were participated, of which 1156 documented subthreshold or threshold retinopathy of prematurity without laser treatment were selected as comparison group and the rest treated with diode or argon laser coagulation were chosen for experiment group. Taking all included studies into account, spherical equivalent (mean difference −2.53, 95% confidence interval: –5.23 to 0.18, I2 = 96%, P < 0.00001), anterior chamber depth (mean difference −0.52, 95% confidence interval: −0.76 to −0.28, I2 = 55%, P = 0.11), astigmatism (odds ratio 3.19, 95% confidence interval: 1.61 to 6.32, I2 = 0%, P = 0.54), and myopia (odds ratio 8.08, 95% confidence interval: 3.79 to 17.23, I2 = 37%, P = 0.21) were associated with laser treatment for retinopathy of prematurity. Axial length (mean difference −0.01, 95% confidence interval: –0.28 to 0.27, I2 = 0%, P = 0.62) and anisometropia (odds ratio 4.21, 95% confidence interval: 0.54 to 33.17, I2 = 1%, P = 0.31) had no statistical significance on laser coagulation for retinopathy of prematurity. Conclusion: This meta-analysis showed that spherical equivalent, anterior chamber depth, astigmatism, and myopia were associated with the negative outcomes of laser coagulation, while axial length and anisometropia had no statistical importance on the defects of laser coagulation. Therefore, patients treated with laser coagulation should follow periodic cycloplegic refraction and receive early optical correction.
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44

Pawloski, John R. "Mechanisms of Hypoxic Erythrovasodilation." Blood 106, no. 11 (November 16, 2005): 1674. http://dx.doi.org/10.1182/blood.v106.11.1674.1674.

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Abstract Red blood cells (RBC) have the unique ability to relax blood vessels under low oxygen conditions (Pawloski et al. Nature409:622, 2001), an activity now termed hypoxic erythrovasodilation (HEV). With human erythrocytes, HEV appears to be mediated, in part, by the export of nitric oxide (NO) bioequivalents formed in the RBC membrane by nitric oxide (NO) group transfer from S-nitrosohemoglobin (SNO-Hb) to cysteine thiols in the cytoplasmic domain of the anion exchanger-1 (AE1 or band 3) protein. Alternatively, HEV has been proposed to be mediated via the nitrite reductase activity of deoxy Hb, resulting in the formation of heme-bound or nitrosyl Hb (HbNO), with subsequent export of NO from the RBC. For both paradigms, downstream export mechanisms, and a precise chemical identity of the discharged specie(s), have yet to be resolved. Interactions between RBCs and vascular tissue (i.e. endothelium and smooth muscle) involved in the HEV response remain undefined, and are the focus of the current study. Rabbit aortic rings were suspended in jacketed organ chambers filled with Krebs-bicarbonate buffer at 37°C, and bubbled continuously with either 21% O2/5% CO2 or 95% argon/5% CO2. Basal tension was maintained at 2 grams, and active tension induced with phenylephrine (PE) or prostaglandin F2a (PGF2a). Fresh (&lt;4 days) or old (&gt;60 days) RBCs were washed and resuspended in phosphate-buffered saline at 50% hematocrit prior to use. Following induction of active tension with PE or PGF2a, changing the aeration gas from O2 to argon resulted in a brisk increase in vascular tone (hypoxic vasoconstriction, HVC). At the peak of this contractile response, RBCs were added to the tissue chambers, causing a dose-dependent relaxation of the rings. There was no correlation between the magnitude of the HVC and that of the ensuing HEV. Following physical removal of the endothelium (confirmed by loss of relaxation to acetylcholine), HVC was unaffected, but HEV was reduced about 20%. In contrast, pretreating the rings with the NO scavenger Hb (100 uM), the NOS inhibitor L-NAME (10 uM), or the soluble guanylate cyclase inhibitor ODQ (10 uM), virtually abolished HVC, while augmenting the HEV response. Deoxygenating RBCs prior to use reduced HEV ~ 50% versus oxyRBCs, while treating the RBCs with carbon monoxide (CO-RBC) abolished HEV. Adding a molar equivalent of purified oxyHb (10 uM), instead of RBCs, at the peak of HVC, resulted in a comparable relaxation response. HEV activity was markedly attenuated using old RBCs, but could be fully restored by pretreating the old RBCs with aqueous NO (1:250 NO:heme) or 1 mM N-acetylcysteine (NAC). NO and NAC treatment did not enhance the HEV of fresh RBCs. In contrast, treating old RBCs with nitrite (100 or 500 nM), or adding nitrite to the tissue bath (100 or 500 nM) had no effect on the HEV response. These results demonstrate that hypoxic erythrovasodilation is a multi-mechanistic biologic response involving the vascular endothelium, oxygen transfer to substrate-limited smooth muscle inducible NOS (iNOS), and possibly a direct vasorelaxant effect on the vascular smooth muscle. Further, we have shown that hypoxic vasoconstriction can occur in non-pulmonary vascular tissue, an effect likely mediated by increased iNOS expression.
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45

Grizzatti, Fabiola, Melissa A. Qazi, David Stroncek, Nathawut Sibmooh, Barbora Piknova, and Alan N. Schechter. "Effect of Storage on Levels of Nitric Oxide Derivatives in Blood Components." Blood 112, no. 11 (November 16, 2008): 999. http://dx.doi.org/10.1182/blood.v112.11.999.999.

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Abstract In light of recent papers stressing the importance of decreased levels of SNO-hemoglobin (SNO-Hb) to the pronounced nature of deleterious effects of transfusion of stored red blood cells (RBCs), there has been an increased interest in the practice of blood storage. Dejam et al. (Blood, 2005) previously demonstrated the critical nature of RBCs in NO physiology: they serve as the major intravascular stores of nitrite, which is eventually converted to NO, an important player in vasoregulation. The purpose of this study is to quantify the NO metabolites, nitrite and nitrate, in three blood components and evaluate their levels over time of storage. Blood obtained from 6 healthy volunteer donors was split into whole blood, leukoreduced, and non-leukoreduced packed RBCs and stored in polyvinyl chloride (PVC) bags for 42 days at 4°C. PVC bags were maintained in either room air or an argon chamber. Nitrite, nitrate, and SNO-Hb/nitrosyl-hemoglobin (HbNO) were measured using reductive gas-phase chemiluminescence. In all blood components, the nitrite and nitrate were detected in higher concentrations in RBCs than in the extracellular fluid compartment. Mean nitrite value immediately before storage was 152±13nM, but fell rapidly upon storage. Nitrite levels continued to decrease with storage time, while nitrate levels remained constant for the duration of storage. In the leukoreduced blood product, nitrite levels were 75±8nM on day 1 and 50±9nM by day 42; the concentration of nitrate in the leukoreduced blood product was 34±3uM on day 1 and 34±4uM on day 42. The nitrite levels in non-leukoreduced blood product were 76±12nM on day 1 and 37±7 by day 42; the nitrate concentration in the non-leukoreduced blood product was 35±3uM on day 1 and 32±0.4uM on day 42. In whole blood, nitrite levels were 64±11nM on day 1 and 44±9nM by day 42; the nitrate concentration was 47±2uM on day 1 and 43±6uM on day 42. SNO-Hb levels were very low in fresh blood and virtually undetectable after one day of storage. Interestingly, nitrite levels never reached zero. Enzyme inhibitors—L-NAME (nitric oxide synthase inhibitor), acetazolamide (carbonic anhydrase inhibitor), and oxypurinol (xanthine oxidase inhibitor)—did not lower nitrite levels enough to explain the remaining nitrite present in the PVC bags after 42 days. pH decreased slightly, while pO2 increased in all three components during storage; this is likely due to the diffusion of oxygen from room air into the PVC bags. Control experiments with saline showed an increase in nitrite levels, while nitrate levels remained stable over 42 days. When stored in an argon chamber, both blood and saline samples showed relatively lower nitrite levels than their room air counterparts. Thus, during blood bank storage, nitrite levels decrease in blood while nitrate levels remain stable. The diffusion of nitrogenous gases may explain why nitrite does not completely disappear under standard storage conditions. Our results suggest that most of the NO pathway is initially retained, but greater changes occur with prolonged storage. These measurements of NO derivatives may have implications for transfusion therapy, explaining some of the adverse effects seen with RBC transfusion and providing a foundation for enhancing blood preservation through improvement of storage practices.
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46

Wada, Satoshi, Fumio Kasahara, Akio Hara, and Hideaki Ikoma. "Oxidation of GaAs Using Helicon-Wave Excited Nitrogen-Oxygen-Argon Plasma." Japanese Journal of Applied Physics 37, Part 2, No. 4B (April 15, 1998): L427—L430. http://dx.doi.org/10.1143/jjap.37.l427.

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47

McKenna, Claire, and Hugo W. van der Hart. "Multiphoton ionization cross sections of neon and argon." Journal of Physics B: Atomic, Molecular and Optical Physics 37, no. 2 (December 17, 2003): 457–70. http://dx.doi.org/10.1088/0953-4075/37/2/013.

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48

Aubreton, J., M. F. Elchinger, V. Rat, and P. Fauchais. "Two-temperature transport coefficients in argon–helium thermal plasmas." Journal of Physics D: Applied Physics 37, no. 1 (December 10, 2003): 34–41. http://dx.doi.org/10.1088/0022-3727/37/1/007.

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49

Laidani, N., R. Bartali, P. Tosi, and M. Anderle. "Argon–hydrogen rf plasma study for carbon film deposition." Journal of Physics D: Applied Physics 37, no. 18 (September 3, 2004): 2593–606. http://dx.doi.org/10.1088/0022-3727/37/18/016.

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50

Marchuk, O., G. Bertschinger, H.-J. Kunze, N. R. Badnell, and S. Fritzsche. "Cascades between doubly excited levels in helium-like argon." Journal of Physics B: Atomic, Molecular and Optical Physics 37, no. 9 (April 24, 2004): 1951–60. http://dx.doi.org/10.1088/0953-4075/37/9/014.

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