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Relevant bibliographies by topics / Aristolochic acids

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Academic literature on the topic 'Aristolochic acids'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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Journal articles on the topic "Aristolochic acids"

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Da Silva, Antonio Jorge Ribeiro, Maria Auxiliadora Coelho Kaplan, Celuta Sales Alviano, Daniela Sales Alviano Moreno, Davi Oliveira e. Silva, and Péricles Barreto Alves. "Determination of Aristolochic Acids I and II in Brazilian Sugar Cane Spirit Infusions “milhomem” Commonly used in Northeast Brazil as Popular Drinks." Revista Fitos 14, no. 01 (2020): 38–44. http://dx.doi.org/10.32712/2446-4775.2020.808.

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Aristolochic acids (AA) are phytochemicals found in plants of the genus Aristolochia belonging to the family Aristolochiaceae. These compounds bear a nitrophenanthrene carboxylic acid skeleton and are reported to be carcinogenic, mutagenic, and nephrotoxic. Sugar cane spirit infusions containing Aristolochia species are commonly used in Brazil as popular drinks, in total absence of scientific information. The presence aristolochic acids was confirmed in samples collected in popular markets of the city of Aracaju, Sergipe, Brazil. The aristolochic acids quantitative estimation was made in five

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Al-Busafi, Saleh, Munir Al-Harthi, and Bushra Al-Sabahi. "Isolation of Aristolochic Acids from Aristolochia Bracteolata and Studies of their Antioxidant Activities." Sultan Qaboos University Journal for Science [SQUJS] 9 (June 1, 2004): 19. http://dx.doi.org/10.24200/squjs.vol9iss0pp19-23.

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The isolation and structural elucidation of aristolochic acid-A and aristolochic acid-D from Omani Aristolochia bracteolata plant is reported. Antioxidant activities of these two natural products were evaluated for their capacity to reduce Mo(VI) to Mo(V). The study revealed that aristolochic acid-D is more active than vitamin C while aristolochic acid-A has activity similar to vitamin C.

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Priestap, Horacio A. "Minor aristolochic acids from Aristolochia argentina and mass spectral analysis of aristolochic acids." Phytochemistry 26, no. 2 (1987): 518–29. http://dx.doi.org/10.1016/s0031-9422(00)81447-8.

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Liu, Jing, Yang Liu, Yingxue Wu, Zhong Dai, and Shuangcheng Ma. "Rapid Analysis of Aristolochic Acid Analogues in Traditional Chinese Patent Medicine by LC-MS/MS." Journal of Analytical Methods in Chemistry 2020 (November 18, 2020): 1–7. http://dx.doi.org/10.1155/2020/8823596.

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Aristolochic acids have been demonstrated to have renal toxicity, cause carcinogenesis, and may cause gene mutations. A series of risk control measurements have been adopted worldwide since 1990s. Some varieties of traditional Chinese medicine with high content of aristolochic acids have been banned in China. However, some species containing aristolochic acids in microscale are still in use. In recent years, with the continuous awareness of drug safety, the aristolochic acid analogues were generally considered to be of potential safety risks. Among these constituents, aristolochic acid I is st

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Houghton, Peter J., and Muzaffer Ogutveren. "Aristolochic acids and aristolactams from Aristolochia auricularia." Phytochemistry 30, no. 1 (1991): 253–54. http://dx.doi.org/10.1016/0031-9422(91)84131-b.

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Yun, Byeong Hwa, Viktoriya S. Sidorenko, Thomas A. Rosenquist, Kathleen G. Dickman, Arthur P. Grollman, and Robert J. Turesky. "New approaches for biomonitoring exposure to the human carcinogen aristolochic acid." Toxicology Research 4, no. 4 (2015): 763–76. http://dx.doi.org/10.1039/c5tx00052a.

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Nascimento, Isabele R., and Lucia M. X. Lopes. "Diterpene esters of aristolochic acids from Aristolochia pubescens." Phytochemistry 63, no. 8 (2003): 953–57. http://dx.doi.org/10.1016/s0031-9422(03)00335-2.

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Suina, Irina Olegovna, Inna Ivanovna Terninko, Yuliya Eduardovna Generalova, Yelena Vladimirovna Burtseva, and Yelizaveta Sergeyevna Bazanova. "STUDY OF SEPARATE FRACTIONS OF ARISTOLOCHIA CLEMATITIS L. HERB FOR THE PRESENCE OF DIFFER-ENT GROUPS OF BAS." chemistry of plant raw material, no. 2 (June 10, 2020): 197–207. http://dx.doi.org/10.14258/jcprm.2020026462.

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The objective of the work was generation of Aristolochia clematitis L. herb fractions and their further study for the presence of different groups of biologically active substances (including aristolochic acids), which was achieved by addressing the following tasks: obtaining fractions from A. clematitis L. herb, preliminary TLC test, HPLC fraction analysis. Fractionation scheme for A. clematitis L. herb extracts was proposed. 4 fractions with different distribution of biologically active substances (chloroform, butanol, ethylacetate and water) were obtained. Using the TLC method and HPLC anal

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Alali, Feras Q., Khaled Tawaha, Mayadah B. Shehadeh, and Suha Telfah. "Phytochemical and Biological Investigation of Aristolochia maurorum L." Zeitschrift für Naturforschung C 61, no. 9-10 (2006): 685–91. http://dx.doi.org/10.1515/znc-2006-9-1013.

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AbstractAristolochia maurorum L. of Jordanian origin has been investigated phytochemically, quantitatively, and biologically. Three atypical alkaloids, namely aristolochic acid I (1), aristolochic acid II (2) and aristolochic acid IIIa (3), have been isolated and identified. Of these known 1-phenanthrenecarboxylic acids, 2 and 3 are reported for the first time from this species. The identified compounds 1-3 were first evaluated biologically as cytotoxic agents against the brine shrimp lethality test (BST), in which compound 1 was found to be the most potent (LC50, 4.9 μg/mL). The antiplatelet

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Santander, Rocío, Alejandro Urzúa, Ángel Olguín, and María Sánchez. "Temporal Variation of Aristolochia chilensis Aristolochic Acids during Spring." Molecules 20, no. 11 (2015): 20391–96. http://dx.doi.org/10.3390/molecules201119704.

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Dissertations / Theses on the topic "Aristolochic acids"

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Liang, Qing You. "Study on supercritical fluid extraction of aristolochic acids in Aristolochia plants." Thesis, University of Macau, 2007. http://umaclib3.umac.mo/record=b1676801.

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Cheung, Thomas Pak Fai, and tom cheung@rmit edu au. "Risk assessment and determination of aristolochic acids and heavy metals in Chinese herbal medicines." RMIT University. Health Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080414.145522.

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There is community concern about toxic contaminants in Chinese herbal medicines. The two areas of contamination that attract most attentions are the nephrotoxic chemical, aristolochic acids found to be present in some Chinese herbs and resulting in renal failure of over 200 patients in Belgium, and heavy metals such as lead, arsenic, cadmium, mercury and chromium, which can cause systemic, CNS, neurological and developmental pathologies. Currently there is a lack of systematic information about the aristolochic acid content in Aristolochia species and related genera, nor have there been any st

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Duquesne, Marilyn. "A translational study of the nephrotoxicity of aristolochic acids by a metabonomic approach in NMR spectroscopy validated by conventional biomarkers." Doctoral thesis, Universite Libre de Bruxelles, 2018. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/268946.

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Utilisation de la métabonomique en spectroscopie RMN pour l'identification de biomarqueurs d'exposition à l'acide Aristolochique. Développement de modèles expérimentaux chez des rats mâles. Analyse d'échantillons urinaires provenant de patients croates potentiellement touchés par la Néphropathie endémique des Balkans<br>Doctorat en Sciences biomédicales et pharmaceutiques (Médecine)<br>info:eu-repo/semantics/nonPublished

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Alamin, Abdelgadir. "Apport de la chromatographie de partage centrifuge à l'étude phytochimique de 3 plantes utilisées en médecine traditionnelle soudanaise." Thesis, Tours, 2016. http://www.theses.fr/2016TOUR3812/document.

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Ce travail de thèse est une contribution à l’étude phytochimique par Chromatographie de Partage Centrifuge (CPC), de trois plantes utilisées en médecine traditionnelle au Soudan : Aristolochia bracteolata (plante entière), Ziziphus spina-christi (feuilles) et Hydnora abyssinica (rhizomes). Ce travail a permis de mettre au point trois méthodologies de purification par CPC, applicables au fractionnement des acides aristolochiques, des flavonoïdes ou des proanthocyanidols (PAC). Dans ce contexte, la première partie de ce manuscrit est consacrée aux notions générales portant sur la CPC. La deuxièm

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Chan, Wan. "Development and application of liquid chromatography and electrospray-ionization mass spectrometry methods for herbal medicine analysis and for the studies of metabolism, DNA adducts and metabonomics of aristolochic acids." HKBU Institutional Repository, 2007. http://repository.hkbu.edu.hk/etd_ra/891.

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Dejan, Miljković. "Histomorfološke, imunohistohemijske i biohemijske karakteristike oštećenja bubrega kod miševa u modelu toksične nefropatije izazvane aristolohičnom kiselinom I." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=108220&source=NDLTD&language=en.

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Uvod: Aristolohična kiselina I je nefrotoksična i kancerogena supstanca koja je odgovorna za nefropatiju koja nastaje usled kori&scaron;ćenja herbalnih preparata i čajeva za mr&scaron;avljenje. S obzirom da se ova supstanca može naći u korovskim biljkama, smatra se jednim od glavnih ekotoksikolo&scaron;kih uzroka za nastanak balkanske endemske nefropatije čiji definitivan uzrok jo&scaron; uvek nije otkriven. Toksičnost ove supstance je dokazana na brojnim animalnim modelima, međutim mehanizmi koji dovode do o&scaron;tećenja bubrežnog parenhima jo&scaron; u potpunosti nisu razja&scaron;njeni.&n

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Zhou, Li, and 周莉. "The molecular mechanisms of aristolochic acid nephropathy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43224349.

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Zhou, Li. "The molecular mechanisms of aristolochic acid nephropathy." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43224349.

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Rodriguez, Isela Iveth Gonzales. "Avaliação da atividade antiofídica de \"Aristolochia sprucei\": Isolamento e caracterização estrutural de composto bioativo." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/60/60134/tde-01092010-005832/.

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Muitas espécies do gênero Aristolochia (Familia Aristolochiaceae) têm sido usadas na medicina tradicional e folclórica como medicamentos e tônicos, as quais demonstravam atividades farmacológicas de interesse clínica e medica como anti-hemorrágica, anti-parasita, antibacteriano, antifúngico, analgésico, antitumoral entre outras. Visando a obtenção de mais informações sobre essas plantas e na procura por substâncias com efeitos antiofídicos, neste trabalho avaliou-se à ação de extratos aquoso, metanólico e de acetato de etila de folhas e caule contra as ações tóxicas da peçonha de Bothrops asp

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Srđan, Živojinov. "Razvoj animalnog modela nefrotoksične tubulointersticijalne lezije." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2016. http://www.cris.uns.ac.rs/record.jsf?recordId=99867&source=NDLTD&language=en.

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U eksperimantalnom postupku disertacije mi&scaron;evi NMRI soja su tretirani infuzom biljke Aristolochia clematitis. Sasu&scaron;eni listovi, grane i plodovi biljke potopljeni su u ključalu vodu i ostavljeni 3-5 sati da stoje, a potom su profiltrirani kroz filter papir. Pravljen je rastvor biljke/vode od 10g/ 1000ml (1%), 20g/ 1000ml (2%) i 40g/ 1000ml (4%). Različite koncentracije infuza su date mi&scaron;evima da piju u neograničenoj količini u periodu od 7 nedelja. Tako su formirane tri ispitne grupe, prva koja je primala 1% infuz, druga 2% infuz i treća 4% infuz i kontrolna grupa koja je d

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Books on the topic "Aristolochic acids"

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Gökmen, M. Refik, and Graham M. Lord. Aristolochic acid nephropathy caused by ingestion of herbal medicinal products. Edited by Adrian Covic. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0089.

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Aristolochic acid nephropathy (AAN) is a rapidly progressive renal disease caused by the ingestion of plant products containing aristolochic acid (AA), first described in connection with the use of Chinese herbal medicines. Although the true worldwide extent of this disease is unknown, it is likely to represent a significant cause of chronic kidney disease (CKD) in many parts of the world. Furthermore, recent data have also demonstrated that AA is also the primary aetiological agent in Balkan endemic nephropathy. AAN is notable in its association with urothelial malignancy, with the mechanisms

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Weaver, Virginia M., Bernard G. Jaar, and Jeffrey J. Fadrowski. Kidney Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190662677.003.0031.

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This chapter describes kidney disorders related to occupational and environmental exposures and addresses prevention and control. Sections address assessment of kidney function, acute kidney injury, and chronic kidney disease (CKD). Kidney disease from acute, high-level exposures as well as lower level exposures in combination with other CKD risk factors are considered. Established nephrotoxicants, including aristolochic acid, arsenic, cadmium, lead, melamine, mercury, silica, and solvents, are discussed. The limited data available on other agents, such as perfluorooctanoic acid and fine parti

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Radović, Milan, and Adalbert Schiller. Balkan endemic nephropathy. Edited by Adrian Covic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0090_update_001.

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Balkan endemic nephropathy (BEN) is a chronic, slowly progressive tubulointerstitial nephritis, with familial clustering, occurring in several endemic rural regions in countries of the Balkan Peninsula. BEN is characterized by anaemia, tubular proteinuria, renal shrinkage, and slowly declining glomerular filtration rate (GFR). Up to one-third of patients may also develop upper urothelial tumours. The aetiology of BEN is unclear; chronic exposure to aristolochic acid and a polygenic predisposition are the most likely contributing factors. The major pathological characteristics of BEN are symmet

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Book chapters on the topic "Aristolochic acids"

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Sidorenko, Viktoriya S. "Biotransformation and Toxicities of Aristolochic Acids." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41283-8_9.

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Yan, Rong, Li Li, and Guan-Hua Du. "Aristolochic Acid." In Natural Small Molecule Drugs from Plants. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8022-7_108.

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Vanherweghem, Jean-Louis, Frederic Debelle, Marie-Carmen Muniz-Martinez, and Joëlle Nortier. "Aristolochic acid nephropathy after Chinese herbal remedies." In Clinical Nephrotoxins. Springer Netherlands, 2003. http://dx.doi.org/10.1007/1-4020-2586-6_29.

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Debelle, Frédéric, Marie-Carmen Muniz-Martinez, Jean-Louis Vanherweghem, and Joëlle Nortier. "Herbal remedies containing aristolochic acid and mushroom nephrotoxicity." In Clinical Nephrotoxins. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-84843-3_33.

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Jelaković, Bojan, Živka Dika, and Arthur P. Grollman. "Endemic (Balkan) Nephropathy: A Disease Caused by Aristolochic Acid." In Environmental and Food Safety and Security for South-East Europe and Ukraine. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-2953-7_20.

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Chen, Chien-Ming, Yih-Huei Uen, Chen-Yi Kuo, Tzu-Chuan Huang, and Jen-Ai Lee. "Fluorimetric Determination of L-3-Hydroxybutyrate Concentrations in the Serum of Normal and Aristolochic Acid-Treated Mice." In Bio-Science and Bio-Technology. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-10616-3_9.

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Schmeiser, H. H., J. Lyons, J. W. G. Janssen, et al. "Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene." In ras Oncogenes. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-1235-3_33.

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Jordan, S. A., and S. Perwaiz. "Aristolochic Acids." In Encyclopedia of Toxicology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-386454-3.01164-7.

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Lamari, Zohra, and Houria Negache. "Analysis of Aristolochia longa L. Medicinal Plant from Algeria." In Trace Elements and Their Effects on Human Health and Diseases. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95298.

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In recent time, the therapeutic use of medicinal plants has increased all over the world. The efficacy of herbs for curative purposes is often accounted of its mineral and organic constituents. Neutron activation analysis (INAA) has been applied to mineral determination of Aristolochia Longa (bereztem), medicinal plant used to cure some diseases observed in Algeria especially cancer. In this work the mass fractions of Cr (15.22 ± 3.5 μg/g), Na (269.98 ± 25.01 μg/g), La (0.478 ± 0.041 μg/g), K (1.33 ± 0.23 μg/g), Br (1.2 ± 0.19 μg/g), As (0.697 ± 0.038) and Sb (66.09 ± 11.24 μg/g), were determined. This herb was collected from Taourirt Aden Berber village situated in Northern Algeria. Five elements were quantified in certified AIEA standards IAEA-V10 and IAEA-SL1 for checking the accuracy of our procedure. It was noteworthy the values obtained from this work are in good agreement with the certified values, the Z-score values for all elements were |Z| < 3. We believe that herb is natural and harmless compared with chemical drugs. Unfortunately the potential toxicity due to the Aristolochia Acids content has required the analysis of Aristolochia Longa by CG/MS and HPLC to highlight this compound. The standard of Aristolochic Acid (Sigma A5512-25 mg Yellow powder lot # wxbb6331VPCODE) was used as reference.

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"Aristolochic Acid Nephropathy." In Diagnostic Pathology: Kidney Diseases. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-37707-2.50148-8.

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Conference papers on the topic "Aristolochic acids"

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Yu, Li-Rong, Zhiguang Li, Yuan Gao, and Tao Chen. "Abstract LB-438: Proteomic analysis of aristolochic acid-induced nephrotoxicity in rats." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-438.

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Edwards, Karen L., Jia Yin Wang, Katherine Snappin, et al. "Abstract 1837: Exposure to Aristolochic Acid is associated with endemic (Balkan) nephropathy." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1837.

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Sidorenko, Viktoriya S., Kathleen G. Dickman, Thomas Rosenquist, et al. "Abstract 5241: Using affinity probes to explore the nephrotoxicity of aristolochic acid." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5241.

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Alkawari, Fatima, Wigdan Ali, Fatiha Benslimane, and Huseyin Yalcin. "Investigating the Cardiac effects of New Generation Anti-Diabetic Drug Empagliflozin using Zebrafish Embryo Model." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0211.

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Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of antidiabetic drugs focused on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism contributing to the CV benefits remains unrevealed. Zebrafish embryos were treated with Aristolochic Acid to induce heart failure then treated with Empagliflozin to determine its beneficial effect. Furthermore the expression of SGLT1 & 2 were determined in the hearts of zebrafish. SGLT2 was expressed more then SGLT1 in the heart and whole embryo. Empa significantly improve

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Grollman, Arthur P. "Abstract PL02-02: Aristolochic acid-induced nephropathy and urothelial carcinoma: A preventable global disease." In Abstracts: Twelfth Annual AACR International Conference on Frontiers in Cancer Prevention Research; Oct 27-30, 2013; National Harbor, MD. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1940-6215.prev-13-pl02-02.

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Lo, Fang Yin, Charles Valentine, Elizabeth Schmidt, et al. "Abstract 3147: Non-invasive detection of aristolochic acid exposure using ultra-sensitive duplex sequencing." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3147.

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Rosenquist, Thomas A., Penelope Strockbine, and Arthur P. Grollman. "Abstract 3253: Genetic loci that contribute to aristolochic acid nephropathy and associated upper urothelial cancer." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3253.

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Chen, Xiaoyi, Qinqin Chai, Xianghui Li, Jie Huang, and Wu Wang. "A Rapidly Method for the Discrimination of Aristolochic Acid and its Analogues Using SVM and PCA." In 2019 Chinese Control Conference (CCC). IEEE, 2019. http://dx.doi.org/10.23919/chicc.2019.8865305.

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Castells, Xavier, Sandra Karanovic, Magali Olivier, et al. "Abstract 305: Ultra-low coverage exome sequencing of FFPE tumor specimens identifies exposure to carcinogenic aristolochic acid." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-305.

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Moussa, Heba Adel Mohamed Lotfy, Gawaher Saleh Abbas Mahgoub, Mashael Ali H. I. Al-Badr, and Huseyin Cagatay Yalcin. "Investigating the Cardiac Effects of Sildenafil loaded Nanoparticles on Heart Failure using the Zebrafish Embryo Model." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0217.

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Background: Cardiovascular diseases (CVDs) are the first cause of death worldwide. Vasolidator agents are used to relax cardiac muscle, but their extremely short half-lifes limit their effectiveness. Sildenafil is such an agent used to relax the blood vessels muscles and increase the blood flow. The conventional drug can lead to serious problems in patients duo to the systematic drug delivery. Use of Nanomedicine potentially can enhance delivery of this agent while reducing the systematic effect of the drug. Aim: The purpose of the research is to examine the effectiveness sildenafil loaded nan

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