Academic literature on the topic 'ARNms'
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Journal articles on the topic "ARNms"
Mencucci, María Victoria, Ana María Rojas Mendoza, Eduardo Andés León, Carolina Román, Luis Emilio Flores, Juan José Gagliardino, Martín Abba, and Bárbara Maiztegui. "P14 Nuevas alteraciones transcripcionales en la patogenia de la diabetes tipo 2 y posible regulación por micro ARNs." Revista de la Sociedad Argentina de Diabetes 54, no. 3Sup (November 21, 2020): 119. http://dx.doi.org/10.47196/diab.v54i3sup.395.
Full textBatista Cunha, Ian Cassiano, and Ricardo Jose Batista Nogueira. "O comércio mundial de armas e a exportação bélica do Brasil." Revista Geonorte 8, no. 28 (May 16, 2017): 178–90. http://dx.doi.org/10.21170/geonorte.2017.v.8.n.28.178.190.
Full textKC, Chitra. "Effect of Chlordecone on the Reproductive Potential of the Cichlid Fish, Pseudetroplus Maculatus (Bloch, 1795)." Journal of Aquatic Research and Marine Sciences 2, no. 2 (May 17, 2019): 163–77. http://dx.doi.org/10.29199/arms/arms-202033.
Full textMikami, Koji. "Diploid Apogamy in Red Algal Species of the Genus Pyropia." Journal of Aquatic Research and Marine Sciences 02, no. 03 (August 5, 2019): 206–8. http://dx.doi.org/10.29199/arms/arms.202033.
Full textEberle, Jakub. "Rüstungsexporte und Menschenrechte." osteuropa 71, no. 4-6 (2021): 273. http://dx.doi.org/10.35998/oe-2021-0040.
Full textWisotzki, Simone. "Rüstungskontrolle und Abrüstung in schwierigen Zeiten." Vereinte Nationen 68, no. 2 (2020): 51. http://dx.doi.org/10.35998/vn-2020-0006.
Full textObaid, Mohammed Mahdi, Idawati Ibrahim, and Noraza Mat Udin. "Zakat and Tax Compliance Behaviour in Yemen: A Conceptual Study." Journal of Advanced Research in Business and Management Studies 19, no. 1 (June 15, 2020): 1–14. http://dx.doi.org/10.37934/arbms.19.1.114.
Full textMohamad Nor, Mohamad Naimi, and Noor Afza Amran. "Temptation and Unethical Activities: A Study on Malaysian Students’ Behaviour." Journal of Advanced Research in Business and Management Studies 19, no. 1 (June 15, 2020): 15–28. http://dx.doi.org/10.37934/arbms.19.1.1528.
Full textZainol Abidin, Hafizah, Rudzidatul Akmam Dziyauddin, and Kamilah Radin Salim. "Issues with New Service Development Process in a Telecommunication Service Provider." Journal of Advanced Research in Business and Management Studies 19, no. 1 (June 15, 2020): 29–41. http://dx.doi.org/10.37934/arbms.19.1.2941.
Full textAbdul Khalik, Zakiah, and Rabihah Md. Sum. "Enterprise Risk Management (ERM) Behaviour Matrix: Mapping ERM Implementations of Non-Financial Public Listed Companies in Malaysia." Journal of Advanced Research in Business and Management Studies 19, no. 1 (June 15, 2020): 42–59. http://dx.doi.org/10.37934/arbms.19.1.4259.
Full textDissertations / Theses on the topic "ARNms"
Rataj, Felicitas. "Nouvelle thérapie anti-tumorale multi-cibles basée sur la dégradation des ARNms à demi-vie courte." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENV040/document.
Full textOne of the innovative aspects of anti-cancer therapies is the possibility of preventing tumor growth by blocking blood supply. Cancer cells induce the formation of their own blood vessels from pre-existing vasculature, a process called angiogenesis. One of the most important proangiogenic factors is vascular endothelial growth factor (VEGF). The success of bevacizumab (a humanized anti-VEGF monoclonal antibody) combined to chemotherapy for the treatment of human metastatic cancers has validated VEGF as an efficient target. However, despite the initial enthusiasm, resistance to these anti-angiogenic treatments resulting from compensatory mechanisms occurs upon time. For this reason, there is a real need for new anti-angiogenic drugs that will target the angiogenic process through distinct mechanisms. In 2010, our laboratory has successfully developed an anti-angiogenic and anti-tumoral therapy based on destabilization of short-lived mRNAs by the zinc finger protein TIS11b. However, the therapeutic protein was highly unstable, thus making it difficult to further characterize the experimental therapy. In this context, the main task of my thesis was the optimization of TIS11b stability and activity followed by the evaluation of the multi-target action of our novel protein on tumor development. In a first part of this work, biochemical and molecular approaches allowed us to demonstrate that phosphorylation of the C-terminal serine S334 in TIS11b protein markedly increases its stability. In addition, deletion of the N-terminal domain of TIS11b highly increases its protein stability without affecting its activity. Therefore, we integrated N-terminal truncation (ZnC) and C-terminal substitution of S334 by an aspartate to mimic a permanent phosphorylation at S334 (ZnCS334D) as a novel TIS11b engineering strategy. Both proteins were fused subsequently to a cell-penetrating peptide polyarginine (R9). In vitro studies revealed that R9-ZnC and R9-ZnCS334D inhibit VEGF expression in the murine breast cancer cells 4T1. In addition, R9-ZnCS334D impaired proliferation, migration, invasion and anchorage-independent growth of 4T1 cells. In vivo, intra-tumoral injection of either protein significantly reduced VEGF expression and tumor vascularization. Strikingly, antibody array analyses of tumor extracts demonstrated a reduced expression of several chemokines such as Fractalkine, MCP-1, NOV, SDF-1 and Pentraxin upon R9-ZnC or R9-ZnCS334D treatment. These factors, which are produced by several cell types within tumor tissue, are key drivers of tumor angiogenesis, tumor-promoting inflammation and invasion. Furthermore, the expression of markers of the epithelial-to-mesenchymal transition was also significantly reduced, suggesting an anti-metastatic effect of R9-ZnC and R9-ZnCS334D. Thus, we provide R9-ZnC and R9-ZnCS334D as potential novel multi-target agents which inhibit key hallmarks of cancer progression. This work supports the emerging link between mRNA stability and cancer and proposes novel concepts for the development of innovative anti-cancer therapies
Baubet, Valérie. "Conséquences du stress par immobilisation sur le sommeil, la synthèse protéique cérébrale et l'expression des ARNms de la pro-opiomélanocortine : approches polygraphique et neuroanatomique chez le rat." Lyon 1, 1996. http://www.theses.fr/1996LYO1T200.
Full textMoreno, Morcillo Maria. "Etude structurale du complexe CstF et de son homologue chez la levure CF IA, deux facteurs indispensables pour la maturation 3' des pré-ARN messagers." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21719/document.
Full textThe removal of the 3’ region of pre-mRNA followed by polyadenylation is a key step in mRNA maturation. In metazoa, Cleavage stimulation Factor (CstF) recognizes U and G/U rich cis-acting RNA sequence elements through its 64kDa subunit and helps stabilize the Cleavage Polyadenylation Stimulating Factor (CPSF) complex at the polyadenylation site. We describe the crystal structure of the N-terminal domain of the CstF-50 subunit. Through highly conserved residues, CstF-50 forms a compact homodimer that exposes two geometrically opposite and identical conserved surfaces. Together with prior data, the structure of the CstF-50 homodimerization domain supports a hexameric model of CstF. The yeast homologue of CstF is the Cleavage/polyadenylation Factor IA (CF IA) complex and is involved in both the cleavage and polyadenylation of pre-mRNA. We have reconstituted ‘in vitro’ the overall complex and also solved the solution structure of one of the inter-subunit regions, specifically the heterodimer involving peptides from Rna14p and Rna15p. Upon binding, a short C-terminal region from Rna14p wraps intimately within the central hinge domain from Rna15p. Conservation of residues reveals that the structural tethering is preserved in the homologous mammalian proteins
La maduración 3’ del pre-ARNm es un proceso clave de la expresión génica que incluye el corte y la poliadenilación del extremo 3’ libre del pre-ARNm. En metazoos, el complejo CstF (Cleavage stimulation Factor) reconoce una secuencia del pre-ARNm rica en U y G/U y permite la estabilización del complejo CPSF (Cleavage Polyadenylation Stimulating Factor) en el sitio de poliadenilación. Hemos descrito la estructura cristalina del dominio N-terminal de una de las tres subunidades de CstF, CstF-50. La estructura ha revelado la organización de la proteína en un dímero compacto y conservado entre las especies. Dos zonas idénticas conservadas se encuentran expuestas a ambos lados de la superficie estructural. Nuestros resultados corroboran así la hipótesis sobre el modelo hexamérico del complejo CstF. CF IA (Cleavage/ polyadenylation Factor IA), el homólogo de CstF en levaduras, interviene en las dos etapas de la maduración 3’. Las bases para la reconstitución del factor CF IA ‘in vitro’ han sido establecidas. Al mismo tiempo, hemos resuelto la estructura del subcomplejo formado por las regiones de interacción de Rna14p y de Rna15p en solución mediante RMN. En el heterodímero, las dos proteínas forman una entidad única a través de la región C-terminal de Rna14p, dominio “monkeytail”, y el dominio “hinge” de Rna15p, quedando las hélices de la dos proteínas entrelazadas. La localización de estos dominios en sus homólogos mamíferos, CstF-77 et CstF-64, sugiere que este tipo de organización está conservada entre las especies
Catrina, Christian. "Arms transfers and dependence /." New York ; Philadelphia ; Washington (D.C.) [etc.] : Taylor & Francis, 1988. http://catalogue.bnf.fr/ark:/12148/cb37445431f.
Full textLarsson, Helena. "The democratic arms export." Thesis, Uppsala universitet, Institutionen för freds- och konfliktforskning, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-341405.
Full textBerger, Michael [Verfasser], Arnis [Akademischer Betreuer] Vilks, and Peter [Akademischer Betreuer] Kesting. "Managermyopie in deutschen Unternehmen : Eine empirische Analyse / Michael Berger. Gutachter: Arnis Vilks ; Peter Kesting. Betreuer: Arnis Vilks." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://d-nb.info/1055992243/34.
Full textWillardson, Spencer L. "Under the influence Of arms: the foreign policy causes and consequences of arms transfers." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/2660.
Full textShortt, Michael. "Arms racing, coercion and war." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86735.
Full textCe mémoire présente un modèle graphique et mathématique du conflit dyadique dans le domaine de la sécurité internationale. Le modèle permet d'interpréter la course aux armements et le déclenchement des guerres dans un cadre formel. Le modèle est construit a partir de concepts rigoureusement définies et nos postulats ont été présenté de manières explicites. Les valeurs d'équilibre pour une course aux armements voulant assurer la sécurité nationale sont prédits à partir du modèle et comparé aux valeurs produites pour une course aux armements avec des objectifs de conquête. Différents résultats d'analyse statique sont comparés pour différentes perturbations du modèle de base. Le modèle est étendu intuitivement pour présenter des scénarios probabilistes de guerre. Finalement, de nombreuses propositions réfutables sont dérivées du modèle.
Skons, Elisabeth. "The Arms Industry and Globalisation." Thesis, University of the West of England, Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522574.
Full textKnowles, Daniel R. T. "Ruthenium complexes bearing pendent arms." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286874.
Full textBooks on the topic "ARNms"
), Marine Corps Institute (U S. Combined arms. Washington, D.C: Marine Corps Institute, Marine Barracks, 1990.
Find full textBook chapters on the topic "ARNms"
Spear, Joanna. "Arms and Arms Control." In Issues in World Politics, 111–33. London: Macmillan Education UK, 1997. http://dx.doi.org/10.1007/978-1-349-25639-6_6.
Full textGoisis, Mario, and Sara Izzo. "Arms." In Outpatient Regenerative Medicine, 237–40. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-44894-7_21.
Full textStella, Enrica, and Alessandro Di Petrillo. "Arms." In Injections in Aesthetic Medicine, 155–58. Milano: Springer Milan, 2013. http://dx.doi.org/10.1007/978-88-470-5361-8_14.
Full textGarthoff, Raymond L. "Security, Arms, and Arms Control." In US Foreign Policy in the 1990s, 104–16. London: Palgrave Macmillan UK, 1991. http://dx.doi.org/10.1007/978-1-349-11220-3_8.
Full textKassab, Hanna Samir, and Jonathan D. Rosen. "Arms Trafficking: Small Arms and WMDs." In Illicit Markets, Organized Crime, and Global Security, 137–54. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90635-5_7.
Full textBourne, Mike. "Arms Trade, Arms Control and Disarmament." In Understanding Security, 158–79. London: Macmillan Education UK, 2014. http://dx.doi.org/10.1007/978-1-137-40210-3_9.
Full textBuzan, Barry. "Arms Racing and the Arms Dynamic." In An Introduction to Strategic Studies, 69–75. London: Palgrave Macmillan UK, 1987. http://dx.doi.org/10.1007/978-1-349-18796-6_5.
Full textLele, Ajey. "Disarmament, Arms Control and Arms Race." In Disruptive Technologies for the Militaries and Security, 217–29. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-3384-2_14.
Full textUva, Michael G. "Lenny arms." In The Grip Book, 223–29. Sixth edition. | New York : Routledge, Taylor & Francis Group, 2018.: Routledge, 2018. http://dx.doi.org/10.4324/9780203702864-13.
Full textHoyos, Alfredo E., and Peter M. Prendergast. "Male Arms." In High Definition Body Sculpting, 119–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54891-8_10.
Full textConference papers on the topic "ARNms"
Gerlt, William R. "ARMS." In the 15th annual conference. New York, New York, USA: ACM Press, 1987. http://dx.doi.org/10.1145/322917.322978.
Full textAmini, Lisa, Raymond Rose, Chitra Venkatramani, Olivier Verscheure, Peter Westerink, and Pascal Frossard. "ARMS." In the eleventh ACM international conference. New York, New York, USA: ACM Press, 2003. http://dx.doi.org/10.1145/957013.957027.
Full textKatayose, Haruhiro, and Kazuhiko Imanishi. "ARMS." In the 2005 ACM SIGCHI International Conference. New York, New York, USA: ACM Press, 2005. http://dx.doi.org/10.1145/1178477.1178545.
Full textKaldor, Mary H. "Beyond Militarism, Arms Races and Arms Control." In The Conflicts of the 20th Century and the Solutions for the 21st Century. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812795496_0008.
Full textHébert, Jean-Paul. "ECONOMIC ANALYSIS OF THE ARMS TRADE AND ARMS PRODUCTION." In Proceedings of the Forty-Ninth Pugwash Conference on Science and World Affairs. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812799647_0029.
Full textCraig, Anthony, and Brandon Valeriano. "Conceptualising cyber arms races." In 2016 8th International Conference on Cyber Conflict (CyCon). IEEE, 2016. http://dx.doi.org/10.1109/cycon.2016.7529432.
Full textHypponen, Mikko. "The cyber arms race." In the 2013 ACM SIGSAC conference. New York, New York, USA: ACM Press, 2013. http://dx.doi.org/10.1145/2508859.2516756.
Full textBroder, Andrei. "A Call to Arms." In WSDM 2018: The Eleventh ACM International Conference on Web Search and Data Mining. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3159652.3160603.
Full textLizotte, Todd E., and Orest P. Ohar. "Tracking illegal small arms traffic across U.S. borders through the implementation of firearm microstamping to small arms and small arms exports." In SPIE Defense, Security, and Sensing, edited by Edward M. Carapezza. SPIE, 2009. http://dx.doi.org/10.1117/12.819504.
Full textMoreno, Robinson Jimenez. "Tracking of human operator arms oriented to the control of two robotic arms." In 2014 XIX Symposium on Image, Signal Processing and Artificial Vision (STSIVA). IEEE, 2014. http://dx.doi.org/10.1109/stsiva.2014.7010125.
Full textReports on the topic "ARNms"
Meyer, Stuart. Small Arms Update. Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada386183.
Full textScarlett, Harry Alan. Treaties and Arms Control. Office of Scientific and Technical Information (OSTI), June 2020. http://dx.doi.org/10.2172/1634914.
Full textDellaVigna, Stefano, and Eliana La Ferrara. Detecting Illegal Arms Trade. Cambridge, MA: National Bureau of Economic Research, August 2007. http://dx.doi.org/10.3386/w13355.
Full textEzell, Virginia H. Small Arms Industrial Base Study. Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada385756.
Full textROCHESTER UNIV NY. USN Small Arms (General Overview). Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada385696.
Full textNAVAL HEALTH RESEARCH CENTER SAN DIEGO CA. USN Small Arms (General Overview). Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada385961.
Full textSmith, Morag Kristin. ACTVD Primer “Arms Control 101”. Office of Scientific and Technical Information (OSTI), April 2019. http://dx.doi.org/10.2172/1506009.
Full textLanghorst, Richard H. US Conventional Arms Transfer Policy. Fort Belvoir, VA: Defense Technical Information Center, April 1996. http://dx.doi.org/10.21236/ada308991.
Full textLaird, Robbin F. West European Arms Control Policy. Fort Belvoir, VA: Defense Technical Information Center, January 1988. http://dx.doi.org/10.21236/ada191519.
Full textKoken, Yusuf Y. Arms Control in Middle East. Fort Belvoir, VA: Defense Technical Information Center, April 1993. http://dx.doi.org/10.21236/ada264568.
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