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Journal articles on the topic 'Aromatic compounds – Synthesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 January 2023

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1

Askerov, O. V., A. F. Mamedova, D. R. Nurullayeva, and G. Dzh Khanbabayeva. "SYNTHESIS AND PROPERTIES OF UNSATURATED AROMATIC OXIRANOSILANES." Chemical Problems 20, no. 2 (2022): 133–37. http://dx.doi.org/10.32737/2221-8688-2022-2-133-137.

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The method of the synthesis of unsaturated aromatic oxiranosilanes by interaction of trialkyl- (aryl)-hydridesilanes with aromatic oxiranes of the acetylene series in the presence of catalyst (platinumhydrochloric acid) in a medium of absolute benzene (yield up to 82-85%) was developed and their properties studied. It was showed that the addition reaction proceeded on a triple bond according to Farmer's rule with the formation of trans-adducts and the maintenance of the oxirane ring. The composition and structure of the obtained unsaturated aromatic oxiranosilanes were confirmed by IR and PMR

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2

Osadchuk, T. V., A. V. Semyroz, O. V. Shybyryn, and V. K. Kibirev. "Synthesis and investigation of the derivatives of amidinohydrazonelated aromatic compounds as furin inhibitors." Ukrainian Biochemical Journal 89, no. 6 (2017): 3–12. http://dx.doi.org/10.15407/ubj89.06.003.

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3

Basu, Aditya, Shree K. Apte, and Prashant S. Phale. "Preferential Utilization of Aromatic Compounds over Glucose by Pseudomonas putida CSV86." Applied and Environmental Microbiology 72, no. 3 (2006): 2226–30. http://dx.doi.org/10.1128/aem.72.3.2226-2230.2006.

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ABSTRACT Pseudomonas putida CSV86, a naphthalene-degrading organism, exhibited diauxic growth on aromatic compounds plus glucose, with utilization of aromatics in the first log phase and of glucose in the second log phase. Glucose supplementation did not suppress the activity of degrading enzymes, which were induced upon addition of aromatic compounds. The induction was inhibited by chloramphenicol, suggesting that de novo protein synthesis was essential. Cells showed cometabolism of aromatic compounds and organic acids; however, organic acids suppressed glucose utilization.

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4

López, Mercedes G., and Dieter W. Gruenwedel. "Synthesis of aromatic Amadori compounds." Carbohydrate Research 212 (June 1991): 37–45. http://dx.doi.org/10.1016/0008-6215(91)84043-e.

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5

Sato, A. "Aromatic compounds synthesis from cyclopentadiene." Applied Catalysis A: General 111, no. 1 (1994): 1–9. http://dx.doi.org/10.1016/0926-860x(94)80063-4.

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6

Hafiz, I. S. Abdel, A. A. Hassanien, and A. M. Hussein. "Alkyl Heteroaromatics as Building Blocks in Organic Synthesis: The Reactivity of Alkyl Azoles toward Electrophilic Reagents." Zeitschrift für Naturforschung B 54, no. 7 (1999): 923–28. http://dx.doi.org/10.1515/znb-1999-0716.

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Oxazolone (1) couples with aromatic diazonium salts to yield the arylhydrazones (3a-c). Compound 3 reacts with aniline to give aryl hydrazone (5). Compound 5 was also obtained via converting 1 into the imidazolone (4) and subsequent treatment of 4 with aromatic diazonium salts. Compounds 1 and 12 reacted with arylidenemalononitrile (6) to yield compounds 8 and 14 respectively. Also compounds 1, 12 condensed with an aromatic aldehydes to yield 11 and 17. Compounds 11, 17 reacted further with one molecule of malononitrile to give compounds 8 and 14, respectively. Compound 20 which was generated

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7

Sobolev, Vasily, Sergey Ivlev, Vladimir Shagalov, Roman Ostvald, and Ivan Zherin. "Synthesis of Highly Deactivated Polyhalogenated Aromatic Compounds." Key Engineering Materials 683 (February 2016): 269–74. http://dx.doi.org/10.4028/www.scientific.net/kem.683.269.

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The barium fluorobromate(III) was obtained as the product of interaction between barium fluoride and bromine(III) trifluoride. The heat of formation of Ba(BrF4)2 was found by isothermal calorimetry method. By the TG/DT analysis the thermal stability of Ba(BrF4)2 was researched. It was found that this compound is mostly stable in the atmosphere or argon up to 250 °C. It was shown that bromine trifluoride and its derive compounds with alkali and alkali-earth metals fluorides can be applied like a highly-active brominating agent in case of production of various composite materials based on polyha

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8

Ando, Akira, Takuichi Miki, and Itsumaro Kumadaki. "Synthesis of 2,2,2-trifluoroethylated aromatic compounds from aromatic amines." Journal of Fluorine Chemistry 35, no. 1 (1987): 48. http://dx.doi.org/10.1016/0022-1139(87)95036-6.

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9

Hamidian, Kourosh, Mohsen Irandoust, Ezzat Rafiee, and Mohammad Joshaghani. "Synthesis, Characterization, and Tautomeric Properties of Some Azo-azomethine Compounds." Zeitschrift für Naturforschung B 67, no. 2 (2012): 159–64. http://dx.doi.org/10.1515/znb-2012-0208.

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The primary azo compound 1-(3-formyl-4-hydroxyphenylazo)-4-nitrobenzene reacts with some aliphatic and aromatic diamines and yields the corresponding azo-azomethine compounds. These compounds were characterized by elemental analysis, IR, UV/Vis, and NMR spectroscopy. The primary azo compound exists entirely in the azo form in solution as well as in the solid phase. The tautomeric structure of azo-azomethine compounds heavily depends on the solvent and the substituents. Aliphatic diamine-based compounds favor the enol-imine tautomer while aromatic diamine-based compounds have structures that li

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10

Syamsudin, Dimas, Ismiyarto Ismiyarto, and Ngadiwiyana Ngadiwiyana. "Synthesis and Antibacterial Testing of Imina Derivative Compounds from Piperonal and Anilin." Jurnal Kimia Sains dan Aplikasi 21, no. 1 (2018): 44–48. http://dx.doi.org/10.14710/jksa.21.1.44-48.

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Synthesis of Imine derivates used as antibacterial activity has been done. Synthesis was conducted by condensation reaction between piperonal and aniline. The product synthesis was characterized by melting point, LC-MS, FTIR and 1H-NMR, then application of the product as antibacterial towards bacteria Staphylococcus aureus and Escherichia coli. The product of synthesis was pale-brown solid, and had melting point at 56-61 0C. Identification by LC-MS showed the compound molecular weight was 225.30 gram/mol, identification by FTIR showed a compound contained imine C=N at 1620.21 cm-1, C-H aromati

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11

Zhang, Bianxiang, Yongqiang Kang, and Ruixue Shi. "Synthesis of Aromatic Heterocyclic Sulfide Compounds." Chinese Journal of Organic Chemistry 36, no. 8 (2016): 1814. http://dx.doi.org/10.6023/cjoc201602021.

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12

Gupta, Vivek Kumar, Baljeet Kaur, Amandeep Kaur, Amanpreet Kaur, and Monika Gupta. "Synthesis and Biological Evaluation of 1,3,4-Oxadiazolyl benzenesulphonyl benzimidazole derivatives." Indian Journal of Pharmaceutical and Biological Research 6, no. 02 (2018): 64–71. http://dx.doi.org/10.30750/ijpbr.6.2.10.

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Oxadiazoles are a class of heterocyclic aromatic chemical compound of azole family. Oxadiazole is five membered heterocycle having two carbons, two nitrogen, one oxygen and two double bonds. Oxadiazole exists in four isomeric forms depending upon the position of nitrogen atom in the ring. Benzimidazole is a heterocyclic aromatic compound. This bicyclic compound consists of fusion of benzene and imidazole. Benzimidazole may also be considered as cyclic analogues of imidines due to tautomerism effect. In the present study involves synthesis of1,3,4-oxadiazolyl benzenesulphonylbenzimidazole deriv

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13

Abdel-Latif, Nehad A. "Synthesis and Antidepressant Activity of Some New Coumarin Derivatives." Scientia Pharmaceutica 73, no. 4 (2005): 193–216. http://dx.doi.org/10.3797/scipharm.aut-05-15.

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The coumarin-3-cinnamoyl derivatives 2a-d were prepared via Claisen-Schmidt condensation of 3-acetylcoumarin 1 with different aromatic aldehydes. Cycloaddition reaction of 2b,e with guanidine and thiourea yielded the corresponding aminopyrmimidine 3a,b and thioxypyrimidine derivatives 4a,b, respectively. Compounds 4a,b were condensed with chloroacetic acid or 3-bromopropionic acid to yield coumarin 3-thiazolo-pyrimidine 5a,b and thiazinopyrimidine 6a,b derivatives, respectively. Compounds 4a,b were condensed with chloroacetic acid and aromatic aldehyde to yield the aryl methylene derivatives 7

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14

Ismail, Hammad, Bushra Mirza, Ihsan-ul Haq, Muhammad Shabbir, Zareen Akhter, and Amina Basharat. "Synthesis, Characterization, and Pharmacological Evaluation of Selected Aromatic Amines." Journal of Chemistry 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/465286.

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Aromatic amines 1-amino-4-phenoxybenzene (A-1A), 2-(4-aminophenoxy) naphthalene (A-2A), and 1-(4-aminophenoxy) naphthalene (A-3A) were synthesized by the reduction of corresponding nitroaromatics with hydrazine monohydrate and Pd/C 5% (w/w). The newly synthesized compounds were characterized by FTIR,1H NMR,13C NMR, UV-visible spectrophotometer, and mass spectrometry and their biological activities were investigated along with structurally similar 4-(4-aminophenyloxy) biphenyl (A-A). Results of brine shrimp cytotoxicity assay showed that almost all of the compounds had LD50values <1 μg/mL. T

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15

Rode, Milind, Sahebrao Rindhe, and Bhausaheb Karale. "Synthesis and biological activities of some indoline derivatives." Journal of the Serbian Chemical Society 74, no. 12 (2009): 1377–87. http://dx.doi.org/10.2298/jsc0912377r.

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The reaction of indoline with a substituted benzoyl chloride in the presence of K2CO3 in THF gave compound 4. Compound 4 was subjected to chlorosulphonation to obtain compound 5. Condensation of aromatic amines with compound 5 led to the synthesis of indoline derivatives 6(a-f). Similarly, 5-nitroindoline was treated with a substituted benzoyl chloride to obtain the nitro compound 9, which was reduced using stannous chloride and reacted further with aromatic sulphonyl chloride to obtain the indoline derivatives 11(a-e). These compounds were tested for antibacterial, anti-tuberculosis and antif

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16

Ravi Kumar, Konda, K. N. S. Sneha Sumanjali, M. Priya Chandana, N. Srilatha, and P. Koteswara Rao. "Synthesis, Characterization and Anti-Microbial Activity of Novel Pyramidine Derivatives." Journal of Drug Delivery and Therapeutics 11, no. 2-S (2021): 98–102. http://dx.doi.org/10.22270/jddt.v11i2-s.4693.

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Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. Three nucleobases found in nucleic acids, cytosine (C), thymine (T), and uracil (U), are pyrimidine derivatives. A pyrimidine has many properties in common with pyridine, as the number of nitrogen atoms in the ring increases the ring pi electrons become less energetic and electrophilic aromatic substitution gets more difficult while nucleophilic aromatic substitution gets easier. Chalcones react with aminoguanidine to give intermedia

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17

Parveen, Mehtab, Afroz Aslam, Shahab A. A. Nami, and Musheer Ahmad. "Z-Acrylonitrile Derivatives: Improved Synthesis, X-ray Structure, and Interaction with Human Serum Albumin." Current Organic Synthesis 16, no. 8 (2020): 1149–60. http://dx.doi.org/10.2174/1570179416666191008085806.

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Aim and Objective: In the synthesis of heterocyclic compounds, acrylonitrile derivatives are the most important and appropriate precursors. These compounds are the most important intermediates and subunits for the enhancement of molecules having pharmaceutical or biological interests. Nitrogen-containing compounds have received extensive consideration in the literature over the years. Materials and Methods: A facile, economic and efficient method has been developed for the synthesis of acrylonitrile derivatives using p-nitrophenylacetonitrile and aromatic/heterocyclic aldehydes in the presence

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18

Jiang, Bo, Yue-Yue Du, and Guo-Zhi Han. "Palladium-mediated base-free and solvent-free synthesis of aromatic azo compounds from anilines catalyzed by copper acetate." Green Processing and Synthesis 11, no. 1 (2022): 823–29. http://dx.doi.org/10.1515/gps-2022-0070.

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Abstract Herein, we report a new one-step direct synthesis of aromatic azo compounds from anilines under mild conditions. With the catalysis of copper acetate mediated by palladium salt, rapid conversion of anilines to aromatic azo compounds can be observed under the conditions of base-free along with solvent-free. Furthermore, the cross-coupling nitridation reaction based on this strategy was also studied. This research provides not only a new way for the synthesis of symmetrical and asymmetrical aromatic azo compounds but also a strategy and platform for exploring catalytic applications of t

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19

YAMAGUCHI, Masahiko. "Synthesis of polycyclic aromatic compounds via polyketides." Journal of Synthetic Organic Chemistry, Japan 45, no. 10 (1987): 969–82. http://dx.doi.org/10.5059/yukigoseikyokaishi.45.969.

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20

ARAI, Sadao, Takamichi YAMAGISHI, and Mitsuhiko HIDA. "Synthesis of Azonia Aromatic Compounds by Photocyclization." Journal of Synthetic Organic Chemistry, Japan 51, no. 1 (1993): 62–67. http://dx.doi.org/10.5059/yukigoseikyokaishi.51.62.

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21

Takaya, H., T. Naota, and H. Terai. "A Facile Synthesis of Fused Aromatic Compounds." Synfacts 2006, no. 5 (2006): 0444. http://dx.doi.org/10.1055/s-2006-934371.

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22

van Otterlo, Willem A. L., and Charles B. de Koning. "Metathesis in the Synthesis of Aromatic Compounds†." Chemical Reviews 109, no. 8 (2009): 3743–82. http://dx.doi.org/10.1021/cr900178p.

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23

Khazaei, Ardeshir, Abbas Amini Manesh, and Vahid Reza Safi. "Regioselective Synthesis of Para-Bromo Aromatic Compounds." Journal of the Chinese Chemical Society 52, no. 3 (2005): 559–62. http://dx.doi.org/10.1002/jccs.200500082.

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24

Datar, Prasanna A., and Sonali R. Jadhav. "Design and Synthesis of Pyrazole-3-one Derivatives as Hypoglycaemic Agents." International Journal of Medicinal Chemistry 2015 (February 4, 2015): 1–10. http://dx.doi.org/10.1155/2015/670181.

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Pyrazole-3-one compounds were designed on the basis of docking studies of previously reported antidiabetic pyrazole compounds. The amino acid residues found during docking studies were used as guidelines for the modification of aromatic substitutions on pyrazole-3-one structure. Depending on the docking score, the designed compounds were selectively prioritized for synthesis. The synthesized compounds were subjected to in vivo hypoglycemic activity using alloxan induced diabetic rats and metformin as a standard. Compound 4 having sulphonamide derivative was found to be the most potent compound

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25

Kuninobu, Yoichiro, Yuta Nishina, Atsushi Kawata, Makoto Shouho, and Kazuhiko Takai. "Rhenium-catalyzed synthesis of indene derivatives via C-H bond activation." Pure and Applied Chemistry 80, no. 5 (2008): 1149–54. http://dx.doi.org/10.1351/pac200880051149.

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Rhenium complex, [ReBr(CO)3(thf)]2-catalyzed reactions between aromatic imines and either acetylenes or α,β-unsaturated carbonyl compounds gave indene derivatives in good to excellent yields. These reactions proceed via C-H bond activation, insertion of acetylenes or α,β-unsaturated carbonyl compounds, intramolecular nucleophilic cyclization, and reductive elimination. Indene derivatives were also obtained from aromatic ketones and α,β-unsaturated carbonyl compounds in the presence of catalytic amounts of the rhenium complex and p-anisidine. Sequential ruthenium-catalyzed hydroamination of aro

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26

Dalal, Meinaa Jaber, and Athraa Hameed Mekky. "Synthesis, Characterization and Antioxidant Evaluation of Some Tetrazole Derivatives." Indonesian Journal of Chemistry 22, no. 6 (2022): 1596. http://dx.doi.org/10.22146/ijc.74912.

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The present study introduces the synthesis of two series of tetrazole derivatives. Firstly, monosubstituted S1 was prepared by the reaction of ethyl 4-aminobenzoate with an amount of sodium azide and triethyl orthoformate in hot glacial acetic acid. Then, ethyl 4-(1H-tetrazol-1-yl) benzoate S1 was treated with a solution of hydrazine hydrate to prepare acetohydrazide S2. After that, tetrazole derivatives S3-S4 were prepared via the reaction of acetohydrazide S2 with various aromatic aldehydes. Secondly, compound 1,5-disubstituted tetrazole S5 was prepared from the reaction of aryl isothiocyana

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27

Diederich, François, and Carlo Thilgen. "Preface." Pure and Applied Chemistry 82, no. 4 (2010): iv. http://dx.doi.org/10.1351/pac20108204iv.

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The 13th International Symposium on Novel Aromatic Compounds (ISNA-13) was held in Luxembourg City, Grand-Duchy of Luxembourg, the smallest country so far hosting a conference of the ISNA series. It took place 19-24 July 2009 and was attended by 360 participants, mostly from academic institutions, representing 34 countries. The scientific program consisted of the Opening Plenary Lecture given by Prof. Jean-Marie Lehn (Institute of Science and Supramolecular Engineering and Louis Pasteur University, Strasbourg), the 2009 Nozoe Lecture presented by Prof. Atsuhiro Osuka (Kyoto University, Kyoto),

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28

Chen, Zhi, Shi-Chao Chen, Bo Li, Yong-An Yang, and Jing Zhang. "Synthesis and Evaluation of Glycyrrhetic Acid-aromatic Hybrids as Anti-inflammatory Agents." Medicinal Chemistry 16, no. 6 (2020): 715–23. http://dx.doi.org/10.2174/1573406415666190603095502.

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Background: : Inflammation is a biological response of body tissues to harmful stimuli, so it is desirable to search for novel anti-inflammatory agents with improved pharmaceutical profiles and reduced adverse effects. Objective: : This study was to explore natural anti-inflammatory agents and improve therapeutic application of glycyrrhetic acid (GA) through molecular hybridization with active aromatics. Methods: : Fourteen novel GA-aromatic hybrids were synthesized and evaluated for their antiinflammatory activities by inhibiting LPS-induced nitric oxide (NO) release in RAW264.7 cells. The sy

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29

Biziks, Vladimirs, Marco Fleckenstein, Carsten Mai, and Holger Militz. "Suitability of a lignin-derived mono-phenol mimic to replace phenol in phenol-formaldehyde resin for use in wood treatment." Holzforschung 74, no. 4 (2020): 344–50. http://dx.doi.org/10.1515/hf-2019-0061.

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AbstractThe goal of this study was to assess the suitability of a single mono-aromatic for substitution of petroleum-based phenol for phenol-formaldehyde (PF) resin synthesis and the usage of a new resin for wood treatment. After proper thermal decomposition of wood-based lignin, pyrolysis oil can be obtained. Due to the heterogeneity of the lignin macromolecule, oil contains large variety of organic-based compounds, mainly mono-aromatics, which are proposed to be used for replacement of phenol during PF resin synthesis. Therefore, for this purpose, nine of the most abundant mono-aromatic comp

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30

Gupta, Monika. "Synthesis and Biological Activity of 6-Substituted Pyrimidine-2,4- Dionesderivatives." International Journal of Pharmacognosy & Chinese Medicine 5, no. 1 (2021): 1–9. http://dx.doi.org/10.23880/ipcm-16000211.

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Cancer is a terrible disease and second leading cause of death, behind cardio-vascular disease in the world. At present, there are three main methods of cancer treatment: surgery, radiation therapy and chemotherapy. Pyrimidineis a six-membered heterocyclic aromatic organic compound containing two nitrogen atoms at positions 1 and 3. Pyrimidine derivatives occupy a distinct and unique place in chemotherapy. The chemotherapeutic efficacy of pyrimidine derivatives is related to their ability to inhibit vital enzymes responsible for DNA biosynthesis as dihydrofolatereductase (DHFR), thymidylatesyn

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31

AL-ALAAF, Hiba Ameen, and Mohammed A. AL-IRAQI. "Synthesis of Some New Hydrazones from Quinazolinone Moiety." Eurasia Proceedings of Science Technology Engineering and Mathematics 16 (December 31, 2021): 52–56. http://dx.doi.org/10.55549/epstem.1068546.

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Methyl α-[(4-oxoquinazolin-2-yl)thio]acetate (4) is one of the important heterocyclic compounds. It isused as a precursor to synthesis new derivatives of quinazolin-4-one moiety. The compound (4) was synthesized via a series of steps from anthranilic acid. The anthranilic acid was converted to its methyl ester (1) by esterification with methanol under acidic condition. The ester (1) was reacted with chloroacetyl chloride to produce methyl α-chloroacetamido benzoate (2). The chloro compound (2) was converted to the corresponding thiocyanato compound (3) by its reaction with ammonium thiocyanate

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32

Sarah Mohammed Abed and Hasan Thamer Ghanem. "Synthesis and characterization Some of heterocyclic compounds from Nitrogen derivative." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (2019): 3186–96. http://dx.doi.org/10.26452/ijrps.v10i4.1621.

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This paper involves the synthesis of new oxazepine derivatives by multi-reaction steps. The first step synthesis azo derivative from 2-naphthol with 3-aminoacetophenone. The second step was the condensation reaction between ketone group of the azo compound and different primary aromatic amines (4-amino phenol, 3-nitro aniline and 4-methyl aniline) to yiled new azo Schiff base compounds (S1-S3) respectively. In the final step, Oxazepine compounds (L1-L3)and (L4-L6)were prepared from reaction imine compounds (S1-S3) with maleic and phthalic anhydride in toluene as solvent. All these derivatives

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33

Kamitanaka, Tohru, Koji Morimoto, Toshifumi Dohi, and Yasuyuki Kita. "Controlled-Coupling of Quinone Monoacetals by New Activation Methods: Regioselective Synthesis of Phenol-Derived Compounds." Synlett 30, no. 10 (2019): 1125–43. http://dx.doi.org/10.1055/s-0037-1611735.

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We have studied for a long time the reaction of quinone acetal type compounds, such as quinone monoacetals, quinone O,S-acetals, and iminoquinone monoacetals, and have reported the regioselective introduction of various nucleophiles. Quinone monoacetals show various types of reactivities toward nucleophiles due to their unique structures. In this study, we found that aromatic and alkene nucleophiles can be regioselectively introduced into the α-position of the carbonyl group on quinone monoacetals by specific activation of the acetal moiety. These reactions enabled the metal-free synthesis of

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34

Abdallah, Tayseer A., Abdellatif M. Salaheldin, and Naglaa F. Radwan. "Studies With Enamines: Synthesis and Reactivity of 4-Nitrophenyl-1-piperidinostyrene. Synthesis of Pyridazine, Oxadiazole, 1,2,3-Triazole and 4-Aminopyrazole Derivatives." Zeitschrift für Naturforschung B 62, no. 2 (2007): 261–66. http://dx.doi.org/10.1515/znb-2007-0218.

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4-Nitrophenyl-1-piperidinostyrene (4) reacts with an aromatic diazonium salt to afford the arylhydrazonal 6. The latter condenses with active methylene compounds to yield pyridazine derivatives, and with hydroxylamine hydrochloride to produce oxadiazole and 1,2,3-triazole derivatives. Compound 12 was reacted with chloroacetonitrile to afford 4-aminopyrazoles 15.

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35

Chiranjeevi, Abba, and Betala Sailu. "Synthesis of novel Schiff’s base functionalized trifluoromethyl pyridine derivatives and their anticancer activity." Research Journal of Chemistry and Environment 26, no. 12 (2022): 139–45. http://dx.doi.org/10.25303/2612rjce1390145.

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A series of novel Schiff’s base functionalized trifluoromethyl pyridine derivatives was prepared starting from pyridine 1. Compound 1 on reaction with sulphuric acid gave compound 2, which on chlorination followed by reaction with hydrazine hydrate produced compounds 3 and 4. Compound 4 on reaction with diverse substituted aromatic aldehyde gave Schiff’s base derivatives 5a-l. All the final compounds were evaluated for anti-cancer activity against four human cancer cell lines such as HeLa - Cervical cancer (CCL-2), COLO 205- Colon cancer (CCL-222), HepG2- Liver cancer (HB-8065) and MCF7 - Brea

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36

Harvey, Ronald. "Advances in the Synthesis of Polycyclic Aromatic Compounds." Current Organic Chemistry 8, no. 4 (2004): 303–23. http://dx.doi.org/10.2174/1385272043485918.

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37

Pei, J., W. Y. Zheng, J. Mao, and X. H. Zhou. "Efficient Synthesis of Thiophene-Based Polycyclic Aromatic Compounds." Synfacts 2006, no. 5 (2006): 0445. http://dx.doi.org/10.1055/s-2006-934384.

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38

Takami, Masaaki, Naomi Hidaka, and Yukio Suzuki. "Phospholipase D-Catalyzed Synthesis of Phosphatidyl Aromatic Compounds." Bioscience, Biotechnology, and Biochemistry 58, no. 12 (1994): 2140–44. http://dx.doi.org/10.1271/bbb.58.2140.

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39

Ward, Gary, Rebecca E. Parales, and Carlos G. Dosoretz. "Biocatalytic Synthesis of Polycatechols from Toxic Aromatic Compounds." Environmental Science & Technology 38, no. 18 (2004): 4753–57. http://dx.doi.org/10.1021/es035458q.

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40

Li, Ang, Daniel J. DeSchepper, and Douglas A. Klumpp. "Triflic acid promoted synthesis of polycyclic aromatic compounds." Tetrahedron Letters 50, no. 17 (2009): 1924–27. http://dx.doi.org/10.1016/j.tetlet.2009.02.042.

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41

Chambers, Richard D., Jock Moilliet, and Michael H. Rock. "The synthesis of bis(trifluoromethyl)aromatic compounds, Lausanne." Journal of Fluorine Chemistry 54, no. 1-3 (1991): 248. http://dx.doi.org/10.1016/s0022-1139(00)83758-6.

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42

Schapiro, Valeria, Gabriel Cavalli, Gustavo A. Seoane, Ricardo Faccio, and Alvaro W. Mombrú. "Chemoenzymatic synthesis of chiral enones from aromatic compounds." Tetrahedron: Asymmetry 13, no. 22 (2002): 2453–59. http://dx.doi.org/10.1016/s0957-4166(02)00682-1.

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Jia-Jie, Wen, Yu Zhu, and Zhuang-Ping Zhan. "The Synthesis of Aromatic Heterocycles from Propargylic Compounds." Asian Journal of Organic Chemistry 1, no. 2 (2012): 108–29. http://dx.doi.org/10.1002/ajoc.201200053.

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Chen, Guoliang, Fangyu Du, Qifan Zhou, et al. "Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki–Miyaura Cross-Coupling by One-Pot Synthesis." Synlett 29, no. 06 (2018): 779–84. http://dx.doi.org/10.1055/s-0036-1591892.

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The aromatic dimers play a significant role in many aspects. Herein, we report a simple palladium-carbon catalyst that is highly effective for the dimerization of brominated aromatic compounds under mild conditions using abundant brominated aromatic compounds, bis(pinacolate)diboron and potassium acetate by a ‘one-pot’ method. This process, which we believe proceeds via a Suzuki–Miyaura cross-coupling reaction mechanism, allows access to a variety of aromatic compounds under mild reaction conditions and has a good functional group tolerance with moderate to high yields.

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Chen, Chih-Wei, and An-Nan Ko. "Synthesis of Aromatic Ketones from Aromatic Compounds Using Vanadium-Containing Mesoporous Silicates." Journal of the Chinese Chemical Society 59, no. 9 (2012): 1104–10. http://dx.doi.org/10.1002/jccs.201100684.

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Assali, Mohyeddin, Murad Abualhasan, Hadeel Sawaftah, Mohammed Hawash, and Ahmed Mousa. "Synthesis, Biological Activity, and Molecular Modeling Studies of Pyrazole and Triazole Derivatives as Selective COX-2 Inhibitors." Journal of Chemistry 2020 (March 24, 2020): 1–14. http://dx.doi.org/10.1155/2020/6393428.

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Series of diaryl-based pyrazole and triazole derivatives were designed and synthesized in a facile synthetic approach in order to produce selective COX-2 inhibitor. These series of derivatives were synthesized by different reactions like Vilsmeier–Haack reaction and click reaction. In vitro COX-1 and COX-2 inhibition studies showed that five compounds were potent and selective inhibitors of the COX-2 isozyme with IC50 values in 0.551–0.002 μM range. In the diarylpyrazole derivatives, compound 4b showed the best inhibitory activity against COX-2 with IC50 = 0.017 μM as one of the N-aromatic rin

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Kwok, Sun. "Synthesis of Organic Compounds in the Circumstellar Environment." Symposium - International Astronomical Union 213 (2004): 181–84. http://dx.doi.org/10.1017/s0074180900193234.

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Recent developments in infrared spectroscopy have made possible the detection of the stretching and bending modes of organic molecules in space. Infrared emission bands of the C-C and C-H stretching and bending modes of aromatic compounds have been widely observed in carbon-rich planetary nebulae, the descendents of carbon stars. Infrared spectra of the transition objects between carbon stars and planetary nebulae, called proto-planetary nebulae, have shown definite signatures of a variety of aliphatic side-groups attached to aromatic rings. This suggests that molecular synthesis is actively o

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Nadeem, Said, Muhammad R. Shah, Kiramat Shah, Akhtar Mohammad, and Burhan Khan. "Synthesis of Diamides and Diimines Derived from 4,4′-(1,3-Phenylenebis(oxy))dianiline, Units for Symmetrical Macrocycles." Organic Chemistry International 2012 (December 31, 2012): 1–10. http://dx.doi.org/10.1155/2012/279097.

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4,4′-(1,3-Phenylenebis(oxy))dianiline 1 is an aromatic diamine compound and has been very less utilized in the organic synthesis. Different diimines and diamides were synthesized by reacting compound 1 with aromatic and heterocyclic compounds having different functionalities. These longer electron rich spacer molecules were synthesized to utilize them in the near future in making macrocycles of different sizes and functionalities. A hydrazide was also prepared from a diamide spacer molecule containing ester group. A diamide prepared containing nibrobenzene moiety was further reduced to amine t

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Mathew, Vinod, J. Keshavayya, and V. P. Vaidya. "Synthesis, Characterization and Pharmacological Activities of 3,6-Disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles and their Dihydro Analogues." E-Journal of Chemistry 4, no. 3 (2007): 320–42. http://dx.doi.org/10.1155/2007/605058.

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4-Amino-5-aryl/heteroaryl substituted-3-mercapto-1,2,4-triazoles 3(a-d) were prepared from the corresponding aromatic carboxylic acids through a multi-step sequence. Compounds 3(a-d) were made to react with various aromatic/hetero aromatic acids and hetero aromatic aldehydes to give 3,6-disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles and 3,6-disubstituted-5,6-dihydro-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles respectively. Elemental analysis, IR,1H NMR and mass spectral data elucidated the structures of all newly synthesized compounds. Synthesized compounds are studied for their antibacte

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Journal, Baghdad Science. "Synthesis and Characterization of New Thioxanthone Derivatives." Baghdad Science Journal 10, no. 3 (2013): 724–35. http://dx.doi.org/10.21123/bsj.10.3.724-735.

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This work comprises the synthesis of new thioxanthone derivatives containing C-substituted thioxanthone. To obtain these derivatives, the o-mercapto benzoic acid was chosen as the starting material, which was reacted with dry benzene in sulfuric acid (98 %) to produce the thioxanthone (1). The 2,7-(disulfonyl phosphine imine) thioxanthone (4-8) were prepared from reaction of compound (1) with chlorosulfonic acid gave 2,7-(disulfonyl chloride) thioxanthone (2). Treatment of (2) with sodium azide to produce 2,7-(disulfonyl azide) thioxanthone (3). Condensation of (3) with phosphorus compounds af

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