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1

Melzig, Matthias F. "Artemisia abrotanum L., Eberraute." Zeitschrift für Phytotherapie 40, no. 06 (2019): 283–88. http://dx.doi.org/10.1055/a-1015-5223.

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ZusammenfassungDie Eberraute, Artemisia abrotanum L., ist eine seit dem Altertum bekannte Arzneipflanze, die traditionell bis ins 19. Jahrhundert bei Bronchial-, Lungen- und Darmkatarrhen genutzt wurde. In der Krautdroge sind neben ätherischem Öl v.a. Phenolsäuren, Cumarine, Flavonoide, Bitterstoffe sowie Peroxidhalbketale enthalten. Wegen des Thujongehaltes im ätherischen Öl einiger Herkünfte besitzt die Droge toxikologische Relevanz. Die pharmakologisch nur wenig untersuchte Arzneipflanze zeigt antimikrobielle, anthelminthische, repellente sowie immunmodulatorische Aktivität, die zur Behandlung der allergischen Rhinitis genutzt werden könnte. Ohne weitere klinische Studien kann die Anwendung der Droge nicht empfohlen werden.
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2

TĂMAȘ, Mircea, Lucian BARBU-TUDORAN, and Ana COSTE. "SECRETORY STRUCTURES IN ARTEMISIA ABROTANUM L. (ASTERACEAE)." Contribuţii Botanice 58 (January 30, 2024): 19–26. http://dx.doi.org/10.24193/contrib.bot.58.2.

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The genus Artemisia includes a large number of aromatic plants that produce secondary metabolites with numerous applications in the health, cosmetics, food and pest management sectors. However, relatively little is known of the dedicated organs where many of these metabolites are synthesized and accumulate. In this context, the aim of this paper was to identify the essential oil-secreting tissue of Artemisia abrotanum L. (Asteraceae) popularly known as southern wormwood. The morphology of its secretory tissue was studied using optical microscopy, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). For the first time, secretory structures composed of stalked bicellular glands have been identified in the leaf sinuses on the abaxial side of the leaf blades. These secretory structures have not been described before in vascular plant taxa indigenous (native or naturalized) to Romania, but were reported in other Asteraceae species worldwide.
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3

Ibrahimova, S., A. Ibrahimov, and A. Alasgarova. "Study of Bioactive Compounds and Resources of Some Species of Wormwood (Artemisia abrotanum L., A. maritima L., A. pauciflora Weber, A. issaevii Rzazade) Distributed in the Flora of Azerbaijan." Bulletin of Science and Practice, no. 6 (June 15, 2023): 54–66. http://dx.doi.org/10.33619/2414-2948/91/05.

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As a result of analysis of the literature data and our research, for the first-time distribution of the species Artemisia abrotanum L., A. maritima L., A. pauciflora Weber, A. issaevii Rzazade in different regions of Azerbaijan by obtaining bioactive compounds typical for them is confirmed in the article in detail. Distribution, resources, ecological features, as well as useful properties of wormwood (Artemisia L.) species found in the flora of Azerbaijan were studied by us, their possibilities of use in various fields of folk and agriculture were recommended. General distribution areas, biological and ecological features of all species were studied. Essential oil was obtained using the Ginsberg hydrodistillation method and component content was determined by the method of Gas Chromato-Mass Spectroscopy. Gas Chromato-Mass Spectroscopy was performed using Agilent 5977A MS gas chromatography and Agilent 7890 GC inert Mass Selector Detector. A. abrotanum L., which is new for the flora of Azerbaijan, two new substances, steroids (β-sitosterol St-1, stigmasterol St-1) was obtained from A. maritima L. species three substances, α-santonin, artemisin, glabellin was obtained. In the composition of the aerial part of the species A. pauciflora Web., 60 terpenoid compounds were identified, 17 components were detected by mass spectroscopy.
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4

Saunoriūtė, Sandra, Ona Ragažinskienė, Liudas Ivanauskas, Mindaugas Marksa, Kristina Laužikė, and Lina Raudonė. "Phenolic Diversity and Antioxidant Activity of Artemisia abrotanum L. and Artemisia absinthium L. during Vegetation Stages." Separations 10, no. 10 (2023): 545. http://dx.doi.org/10.3390/separations10100545.

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Over the past ten years, particular attention has been paid to Artemisia L. genus plants and their chemical composition. Artemisia abrotanum L. and Artemisia absinthium L., which are traditional medicinal, aromatic plants with a strong digestive activity that is determined by the various phytochemicals. The research aim was to determine the variation in polyphenols in the samples of different vegetation stages of two Artemisia species and to evaluate the antioxidant activity of methanolic extracts in vitro. Phytochemical analysis of the Artemisia samples was carried out using spectrophotometric methods and HPLC-PDA techniques, while antioxidant activity was determined using DPPH, ABTS, FRAP, and CUPRAC assays. Significant differences in the diversity of phenolic compounds were found among Artemisia species during vegetation stages. Chlorogenic acid, 3,5-dicaffeoylquinic acid, and rutin were predominant among the phenolic compounds. The study provides valuable insights into the composition of phenolic compounds and flavonoids in Artemisia plants at different growth stages, shedding light on their potential pharmacological effects and antioxidant activities. These findings contribute to the knowledge of the quality and safety of herbal materials derived from Artemisia species.
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5

Hrytsyk, Roman Andriiovych, Roman Volodymyrovych Kutsyk, Oxana Ivanivna Yurchyshyn, Оxana Аnatolievna Struk, Igor Vladimirovich Kireev, and Andrii Romanovych Grytsyk. "The investigation of antimicrobial and antifungal activity of some Artemisia L. species." Pharmacia 68, no. (1) (2021): 93–100. https://doi.org/10.3897/pharmacia.68.e47521.

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Background: Throughout history pathogenic microorganisms cause infectious diseases. Medicinal herbs play an important role in human life because they are used for the therapy and production of herbal remedies. Therefore, it is relevant to study the antibacterial activity of medicinal herbs including Artemisia L. species. Aim: The purpose of this study was to investigate the antimicrobial and antifungal activity of Artemisia L. species extracts and to identify their synergistic antimicrobial effects with erythromycin against skin isolates of Staphylococcus aureus with different mechanisms of MLS-resistance. Materials and methods: Artemisia absinthium L. herb extracts (AAs-4, AAs-7, AAs-9), Artemisia vulgaris L. herb extracts (AV-4, AV-7, AV-9) and Artemisia abrotanum L. herb extracts (AAr-4, AAr-7, AAr-9) were used in this study (solvents – 40%, 70% and 90% ethyl alcohol respectively). The determination of antimicrobial activity of extracts was performed using clinical isolates of antibiotic susceptible and antibiotic resistant microorganisms. Bacterial cultures were identified on the basis of the biochemical microtests "STAPHYtest 16", "ENTEROtest 24", "NEFERMENTtest 24" taking into account the complex of their morphological and cultural properties in accordance with the recommendations of the 9<sup>th</sup> edition of "Bergey's Manual of Systematic Bacteriology". Yeast-like fungi cultures were identified on the basis of 40 biochemical tests with the help of the VITEK 2 system using the VITEK 2 YST ID card. The synergism of the antimicrobial activity of extracts with erythromycin was investigated using the clinical isolate of Staphylococcus aureus with the non-inductive MLS-resistance mechanism (resistant to erythromycin at minimum bacteriostatic concentration of 125 μg/ml and minimum bactericidal concentration of 250 μg/ml without induction of resistance to clindamycin). Research results: The evaluation of Artemisia L. herb extracts activity was carried out using standard strains of microorganisms which are recommended by the WHO. The results of the conducted studies indicate that Artemisia L. herb extracts are able to reduce the growth of microorganisms. The investigated extracts showed the potent bacteriostatic action against the cocci or rod-shaped microflora. The antimicrobial activity of Artemisia L. herb extracts directly depends on the concentration of ethanol as the solvent. Artemisia vulgaris L. herb extracts (solvents – 70% and 90% ethanol) and Artemisia abrotanum L. herb extract (solvent – 90% ethanol) show synergism of antimicrobial activity with erythromycin in relation to Staphylococcus aureus with efflux mechanism of MLS-resistance. The obtained Artemisia L. herb extracts can be used to create antifungal drugs, as well as antimicrobial drugs (against gram-positive and gram-negative bacteria).
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6

Elansary, Hosam O., Agnieszka Szopa, Paweł Kubica, et al. "Polyphenol Content and Biological Activities of Ruta graveolens L. and Artemisia abrotanum L. in Northern Saudi Arabia." Processes 8, no. 5 (2020): 531. http://dx.doi.org/10.3390/pr8050531.

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Natural populations of Ruta graveolens L. and Artemisia abrotanum L. in northern Saudi Arabia may be a rich source of natural polyphenols with potential biological activities. Therefore, tentative high-performance liquid chromatography–diode array detection was used to analyze the polyphenol contents of leaf extracts. R. graveolens mainly contained the phenolic acids chlorogenic acid and p-coumaric acid and the flavonoids rutoside and quercetin, whereas those of A. abrotanum mainly contained the phenolic acids isochlorogenic acid and rosmarinic acid and the flavonoid quercetin. Leaf extracts of both species showed antioxidant activities due to the presence of quercetin, chlorogenic acid, and p-coumaric acid as well as antiproliferative and cytotoxic activities against cancer cells, which may be attributed to necrotic cell accumulation during the early and late apoptotic periods. Both species also exhibited antibacterial activity, although the activity was higher in R. graveolens due to the high contents of quercetin and other polyphenols. Finally, both species exhibited antifungal activities, which were associated with specific polyphenols. This is the first study to confirm the richness of polyphenols and wide spectrum of biological activities in natural populations of R. graveolens and A. abrotanum in northern Saudi Arabia.
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7

Ivashchenko, I. V. "ФУНГІЦИДНІ ВЛАСТИВОСТІ ЕФІРООЛІЙНИХ РОСЛИН РОДУ ARTEMISIA ВІДНОСНО FUSARIUM OXYSPORUM". Biological Bulletin of Bogdan Chmelnitskiy Melitopol State Pedagogical University 5, № 02 (2015): 44. http://dx.doi.org/10.15421/2015016.

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&lt;p&gt;The article establishes the fungicidal activity of water extracts of &lt;em&gt;Artemisia&lt;/em&gt;&lt;em&gt; &lt;/em&gt;&lt;em&gt;maritim&lt;/em&gt;&lt;em&gt;а&lt;/em&gt; L., &lt;em&gt;Artemisia&lt;/em&gt;&lt;em&gt; &lt;/em&gt;&lt;em&gt;austriaca Jacq.,&lt;/em&gt; under the concentration of 100, 50 and 25 mg/ml on dry matter with regard to the phytopathogenic mushroom &lt;em&gt;Fusarium oxysporum&lt;/em&gt;. It also shows the fungistatic influence of extract of Artemisia dracunculus L. under concentration 25 and 50 mg/ml, fungicidal – under 100 mg/ml. Concerning &lt;em&gt;Artemisia abrotanum&lt;/em&gt; L., the slow growth of mushroom is observed under the concentration 25 mg/ml, fungicidal effect – under 50 and 100 mg/ml.&lt;/p&gt; &lt;p&gt;The paper provides the information on the component composition of ethereal oil and phenolic compounds of &lt;em&gt;Artemisia&lt;/em&gt;&lt;em&gt; &lt;/em&gt;&lt;em&gt;maritim&lt;/em&gt;&lt;em&gt;а&lt;/em&gt;, &lt;em&gt;Artemisia&lt;/em&gt;&lt;em&gt; &lt;/em&gt;&lt;em&gt;austriaca&lt;/em&gt;,&lt;em&gt; Artemisia abrotanum&lt;/em&gt;&lt;em&gt;, &lt;/em&gt;&lt;em&gt;Artemisia dracunculus&lt;/em&gt;, cultivated in Zhytomyr Polissya. The chief ingredients of ethereal oil which is synthesized by the plant of &lt;em&gt;Artemisia &lt;/em&gt;&lt;em&gt;abrotanum&lt;/em&gt; are 1,8-cineole (30.44%) and camphor (31.92%). A high 1,8-cineole and camphor content determines antimicrobial properties of the plants.&lt;/p&gt; &lt;p&gt;Amount of phenolic compounds in the air-dry raw &lt;em&gt;Artemisia &lt;/em&gt;&lt;em&gt;abrotanum&lt;/em&gt; is 2.98 percent. By the method of highly efficient solution chromatography (HESChr) in the grass of &lt;em&gt;Artemisia abrotanum &lt;/em&gt;we have detected 23 phenolic compounds, of which we identified such flavonoids as rutin, luteolin-7-glycoside as well as caffeic, chlorogenic and isochlorogenic acids.&lt;/p&gt; &lt;p&gt;The main compounds of ethereal oil of &lt;em&gt;Artemisia austriaca&lt;/em&gt; are trans-verbenole (30.77 %), pinocarvone (10.77 %) and sabinilacetate (18.16 %).&lt;strong&gt; &lt;/strong&gt;In the grass of &lt;em&gt;Artemisia austriaca &lt;/em&gt;we have detected 31 phenolic compounds, of which we identified such flavonoids as rutin, apigenin, quercetin-bioside and the following acids: caffeic, chlorogenic, and isochlorogenic. Amount of phenolic compounds in the air-dry raw Austrian wormwood is 27.25 mg / g (2.73 %).&lt;/p&gt; &lt;p&gt;The main component of ethereal oil of &lt;em&gt;Artemisia dracunculus is &lt;/em&gt;methyleugenol (94.65 %). We have discovered 31 phenolic compounds in the grass of linear-leaved wormwood, from which four substances such as rutin, luteolin-7-glycoside, apigenin-7-glycoside and isochlorogenic acid have been identified. The dominant compounds of ethereal oil of &lt;em&gt;Artemisia maritima&lt;/em&gt; are α-thujone (41.59 %) and camphor (23.56 %).&lt;/p&gt; &lt;p&gt;Obviously, the fungicidal properties of plants are conditioned by the quantitative and qualitative content of biologically active substances – ethereal oils, fenolic compounds and other matters. The paper draws attention to the prospects of the further more detailed study of extracts of&lt;strong&gt; &lt;/strong&gt;aromatic plants of the genus &lt;em&gt;Artemisia&lt;/em&gt; with the aim of producing antibacterial and antifungal herbal preparations.&lt;/p&gt; &lt;p&gt;&lt;em&gt;Key words&lt;strong&gt;:&lt;/strong&gt;&lt;/em&gt;&lt;strong&gt;&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Artemisia, Fusarium oxysporum, water extract, fungicidal activity, aromatic plants.&lt;/em&gt;&lt;/p&gt; &lt;p&gt;&lt;em&gt; &lt;/em&gt;&lt;/p&gt;
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8

Hrytsyk, Roman Andriiovych, Roman Volodymyrovych Kutsyk, Oxana Ivanivna Yurchyshyn, Оxana Аnatolievna Struk, Igor Vladimirovich Kireev, and Andrii Romanovych Grytsyk. "The investigation of antimicrobial and antifungal activity of some Artemisia L. species." Pharmacia 68, no. 1 (2021): 93–100. http://dx.doi.org/10.3897/pharmacia.68.e47521.

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Background: Throughout history pathogenic microorganisms cause infectious diseases. Medicinal herbs play an important role in human life because they are used for the therapy and production of herbal remedies. Therefore, it is relevant to study the antibacterial activity of medicinal herbs including Artemisia L. species. Aim: The purpose of this study was to investigate the antimicrobial and antifungal activity of Artemisia L. species extracts and to identify their synergistic antimicrobial effects with erythromycin against skin isolates of Staphylococcus aureus with different mechanisms of MLS-resistance. Materials and methods: Artemisia absinthium L. herb extracts (AAs-4, AAs-7, AAs-9), Artemisia vulgaris L. herb extracts (AV-4, AV-7, AV-9) and Artemisia abrotanum L. herb extracts (AAr-4, AAr-7, AAr-9) were used in this study (solvents – 40%, 70% and 90% ethyl alcohol respectively). The determination of antimicrobial activity of extracts was performed using clinical isolates of antibiotic susceptible and antibiotic resistant microorganisms. Bacterial cultures were identified on the basis of the biochemical microtests “STAPHYtest 16”, “ENTEROtest 24”, “NEFERMENTtest 24” taking into account the complex of their morphological and cultural properties in accordance with the recommendations of the 9th edition of “Bergey’s Manual of Systematic Bacteriology”. Yeast-like fungi cultures were identified on the basis of 40 biochemical tests with the help of the VITEK 2 system using the VITEK 2 YST ID card. The synergism of the antimicrobial activity of extracts with erythromycin was investigated using the clinical isolate of Staphylococcus aureus with the non-inductive MLS-resistance mechanism (resistant to erythromycin at minimum bacteriostatic concentration of 125 μg/ml and minimum bactericidal concentration of 250 μg/ml without induction of resistance to clindamycin). Research results: The evaluation of Artemisia L. herb extracts activity was carried out using standard strains of microorganisms which are recommended by the WHO. The results of the conducted studies indicate that Artemisia L. herb extracts are able to reduce the growth of microorganisms. The investigated extracts showed the potent bacteriostatic action against the cocci or rod-shaped microflora. The antimicrobial activity of Artemisia L. herb extracts directly depends on the concentration of ethanol as the solvent. Artemisia vulgaris L. herb extracts (solvents – 70% and 90% ethanol) and Artemisia abrotanum L. herb extract (solvent – 90% ethanol) show synergism of antimicrobial activity with erythromycin in relation to Staphylococcus aureus with efflux mechanism of MLS-resistance. The obtained Artemisia L. herb extracts can be used to create antifungal drugs, as well as antimicrobial drugs (against gram-positive and gram-negative bacteria).
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9

Hrytsyk, Roman Andriiovych, Roman Volodymyrovych Kutsyk, Oxana Ivanivna Yurchyshyn, Оxana Аnatolievna Struk, Igor Vladimirovich Kireev, and Andrii Romanovych Grytsyk. "The investigation of antimicrobial and antifungal activity of some Artemisia L. species." Pharmacia 68, no. 1 (2021): 93–100. http://dx.doi.org/10.3897/pharmacia.68.e47521.

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Background: Throughout history pathogenic microorganisms cause infectious diseases. Medicinal herbs play an important role in human life because they are used for the therapy and production of herbal remedies. Therefore, it is relevant to study the antibacterial activity of medicinal herbs including Artemisia L. species. Aim: The purpose of this study was to investigate the antimicrobial and antifungal activity of Artemisia L. species extracts and to identify their synergistic antimicrobial effects with erythromycin against skin isolates of Staphylococcus aureus with different mechanisms of MLS-resistance. Materials and methods: Artemisia absinthium L. herb extracts (AAs-4, AAs-7, AAs-9), Artemisia vulgaris L. herb extracts (AV-4, AV-7, AV-9) and Artemisia abrotanum L. herb extracts (AAr-4, AAr-7, AAr-9) were used in this study (solvents – 40%, 70% and 90% ethyl alcohol respectively). The determination of antimicrobial activity of extracts was performed using clinical isolates of antibiotic susceptible and antibiotic resistant microorganisms. Bacterial cultures were identified on the basis of the biochemical microtests “STAPHYtest 16”, “ENTEROtest 24”, “NEFERMENTtest 24” taking into account the complex of their morphological and cultural properties in accordance with the recommendations of the 9th edition of “Bergey’s Manual of Systematic Bacteriology”. Yeast-like fungi cultures were identified on the basis of 40 biochemical tests with the help of the VITEK 2 system using the VITEK 2 YST ID card. The synergism of the antimicrobial activity of extracts with erythromycin was investigated using the clinical isolate of Staphylococcus aureus with the non-inductive MLS-resistance mechanism (resistant to erythromycin at minimum bacteriostatic concentration of 125 μg/ml and minimum bactericidal concentration of 250 μg/ml without induction of resistance to clindamycin). Research results: The evaluation of Artemisia L. herb extracts activity was carried out using standard strains of microorganisms which are recommended by the WHO. The results of the conducted studies indicate that Artemisia L. herb extracts are able to reduce the growth of microorganisms. The investigated extracts showed the potent bacteriostatic action against the cocci or rod-shaped microflora. The antimicrobial activity of Artemisia L. herb extracts directly depends on the concentration of ethanol as the solvent. Artemisia vulgaris L. herb extracts (solvents – 70% and 90% ethanol) and Artemisia abrotanum L. herb extract (solvent – 90% ethanol) show synergism of antimicrobial activity with erythromycin in relation to Staphylococcus aureus with efflux mechanism of MLS-resistance. The obtained Artemisia L. herb extracts can be used to create antifungal drugs, as well as antimicrobial drugs (against gram-positive and gram-negative bacteria).
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10

Torrell, Montserrat, Maria Bosch, Joan Martín, and Joan Vallès. "Cytogenetic and isozymic characterization of the narrow endemic species Artemisia molinieri (Asteraceae, Anthemideae): implications for its systematics and conservation." Canadian Journal of Botany 77, no. 1 (1999): 51–60. http://dx.doi.org/10.1139/b98-193.

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We carried out a cytogenetic and isozymic study of Artemisia molinieri Quézel, Barbero, &amp; R. Loisel (Asteraceae, Anthemideae), a narrow endemic species limited to two populations in southeastern France. Fine karyotype analysis, including fluorochrome banding, enabled us to discuss the systematic affinities of this taxon, which is closely related to Artemisia abrotanum L. and Artemisia chamaemelifolia Vill. Isozyme electrophoresis showed higher genetic variability than expected for a plant with a very restricted geographic distribution. These data, along with the results of a study of pollen viability and some ecological factors, led us to propose some ideas concerning the conservation strategy for this rare plant species.Key words: Artemisia molinieri, Asteraceae, cytogenetics, isozyme variability, systematics, conservation, narrow endemic species.
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11

Besliu, Daniela, Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Ileana Rau, and Aurelia Meghea. "Lipo-nanosilver composites biogenerated using Artemisia abrotanum L. aqueous extract." Molecular Crystals and Liquid Crystals 694, no. 1 (2019): 40–48. http://dx.doi.org/10.1080/15421406.2020.1723895.

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12

Ekiert, Halina, Ewa Knut, Joanna Świątkowska, et al. "Artemisia abrotanum L. (Southern Wormwood)—History, Current Knowledge on the Chemistry, Biological Activity, Traditional Use and Possible New Pharmaceutical and Cosmetological Applications." Molecules 26, no. 9 (2021): 2503. http://dx.doi.org/10.3390/molecules26092503.

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Artemisia abrotanum L. (southern wormwood) is a plant species with an important position in the history of European and Asian medicine. It is a species famous as a medicinal plant in Central Asia, Asia Minor, and in South-East and Central Europe. The raw materials obtained from this species are Abrotani herba and Abrotani folium. In the traditional European medicine, they have been used successfully most of all in liver and biliary tract diseases, in parasitic diseases in children and as antipyretic medication. In the official European medicine, this plant species is recommended by the French Pharmacopoeia for use in homeopathy. In many European countries, it is used traditionally in allopathy. The latest studies on the biological activity of extracts from the aboveground parts of the plant and/or the leaves, and/or the essential oil have provided evidence of other possible applications related to their antibacterial, antifungal, antioxidant, anticancer, and antiallergic properties. The latest studies have also focused on the repellent activity of the essential oil of this species and the possibility to use it in the prevention of diseases in which insects are the vectors. The main substances obtained from the plant that are responsible for this activity are: the essential oil, coumarins, phenolic acids, and flavonoids. Some of the latest investigations emphasize the large differences in the composition of the essential oil, determined by the geographical (climatic) origin of the plant. A. abrotanum is recommended by the European Cosmetic Ingredients Database (CosIng) as a source of valuable cosmetic ingredients. Additionally, the leaves of this species possess a well-established position in the food industry. This plant species is also the object of biotechnological studies.
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Kruglov, Dmitriy Semenovich, and Dar'ya Leonidovna Prokusheva. "THE TRACE-ELEMENT CONSTITUENTS OF THE MOST WIDESPREAD PLANTS OF GENUS ARTEMISIA." chemistry of plant raw material, no. 3 (September 26, 2022): 139–49. http://dx.doi.org/10.14258/jcprm.20220310800.

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In the presented work, research of the trace element composition of the most common plants of the genus Artemisia (A. abrotanum L., A. absintium L., A. annua L., A. austriaca Jacq., A. bargusinensis Spreng, A. caucasica Willd, A. cericea Weber, A. commutata Bess, A. campestris L., A. dracunculus L., A. frigida Willd, A. glauca Pall, A. gmelinii Web, A. hololeuca M.Bieb., A. jacutica Drob, A. lagocephala DC, A. latifolia Ledeb, A. leucophylla Turcz, A. macrantha Ledeb, A. macrocephala Jacq, A. mongolica Fisch, A. obtusiloba Ledeb, A. opulenta Pampan, A. pontica L., A. rupestris L.,A. santolinifolia Turcz, A. scoparia Waldst, A. siversiana Willd, A. tanacetiflia L., A. tomentella Trantv, A. vulgaris L.) was done. The content of 58 elements was determined by mass-spectroscopy with inductively coupled plasma. At next stage the dendrogram was constructed with using cluster analysis of the obtained data. The division of plants into clusters correlates with their taxonomy positions. In addition, built clusters turned out to be significantly different in content and trace elements of the hematopoietic complex. As a result, it was concluded that species of Artemisia section, including the widespread Artemisia vulgaris, have an optimal relation of hematopoietic complex trace elements.
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Aruba, Omar Salim, Gaith Ali Jasim, and Abdulmutalib A. Nasser. "Detection of terpenes of Iraqi Artemisia abrotanum L. by GC/MS in hexane extract." Al Mustansiriyah Journal of Pharmaceutical Sciences 19, no. 4 (2019): 239–48. http://dx.doi.org/10.32947/ajps.v19i4.656.

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Artemisia abrotanum L. is recently introduced plant in Iraq, in this study we conducted GS/MS for detection of terpene that are group of constituents abundant in this species qualitatively and quantatively. We used hexane extract for the detection depending on the like dissolve like proce-&#x0D; dure of extraction since they are mostly nonpolar compounds, they dissolve in nonpolar solvent like hexane thus the extraction procedure is conducted with this solvent. New compound was detected with hexane extract that wasn't present in previous studies.
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15

Bolyard, Mark. "In vitro regeneration of Artemisia abrotanum L. by means of somatic organogenesis." In Vitro Cellular & Developmental Biology - Plant 54, no. 1 (2017): 127–30. http://dx.doi.org/10.1007/s11627-017-9878-6.

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16

Коrablova, O. A., D. B. Rakhmetov, M. I. Shanaida, et al. "The content of macro- and microelements in plants of the genus Artemisia under conditions of introduction in the M. M. Gryshko National Botanical Garden of the NAS of Ukraine." Plant varieties studying and protection 17, no. 3 (2021): 199–209. http://dx.doi.org/10.21498/2518-1017.17.3.2021.242983.

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Purpose. To determine mineral composition of plants of species of the genus Artemisia (A. dracunculus L., A. abrotanum L. and A. argyi H.Lév. &amp; Vaniot) to determine the possibility of their safe use in the food and pharmaceutical industries of Ukraine. Methods. X‑ray fluorescence method for determining the elemental composition of plant raw materials. Results. The content of mineral elements in plants of the genus Artemisia was determined depending on their ability to absorb elements from the soil and accumulate in the roots and organs of the aerial part was determined. The quantitative content of 21 macro- and microelements was established, and some peculiarities of their migration and distribution in the soil – roots – plant system were revealed. In particular, the aerial part of the studied plants contains K, Fe, Cu, Zn and Mn, which are the most important elements in the life of the plant organism. The content of mesoelements Ca and S is quite high. The amount of toxic elements Pb, Sr and Zr in plants is insignificant. Elements K and S accumulate in the aerial part. The content of elements in the aerial part of plants by decreasing their concentration can be represented in the form of the following series: for Artemisia dracunculus – S&gt; K&gt; Ca&gt; Cl&gt; Fe&gt; Sr&gt; Zn&gt; Mn&gt; Cu&gt; Zr&gt; Rb&gt; Br&gt; Cr; for A. abrotanum – K&gt; Ca&gt; S&gt; Cl&gt; Fe&gt; Zn&gt; Sr&gt; Mn&gt; Cu&gt; Br&gt; Cr&gt; Co&gt; Zr&gt; Rb&gt; Ni; for A. argyi – K&gt; Ca&gt; S&gt; Fe&gt; Cl&gt; Sr&gt; Zn&gt; Mn&gt; Co&gt; Zr&gt; Cu&gt; Rb&gt; Br&gt; Se. The content of toxic elements in the studied plants was lower than the maximum allowable concentrations for plant raw materials and food. Conclusions. For the first time under conditions of introduction in the M. M. Gryshko National Botanical Garden of the NAS of Ukraine in the plants Artemisia dracunculus, A. abrotanum and A. argyi the content of macro- and microelements, which are directly related to the metabolism of biologically active compounds, was determined. The peculiarities of their distribution by plant organs during the transition from soil to aboveground mass have been clarified. The obtained results can be used to evaluate and compare the quality of plant raw materials of the genus Artemisia, to determine the pharmacological properties of these plants associated with some elements of the mineral composition, and their use in the medical and food industries. The obtained data have both scientific and practical significance in the selection of economically valuable plant species for the enrichment of the cultivated flora of Ukraine.
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Almahdawy, Sarah S., Ali Muaffaq Said, Ibrahim S. Abbas, and Ashour H. Dawood. "THE EVALUATION OF ANTIMICROBIAL AND CYTOTOXIC ACTIVITY OF THE ESSENTIAL OIL EXTRACTED FROM THE AERIAL PARTS OF SOUTHERNWOOD HERB (ARTEMISIA ABROTANUM L.) THAT RECENTLY GROWN IN IRAQ." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 384. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.21725.

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Objective: This research is to study the assessment of the antimicrobial and cytotoxic activity of the essential oil extracted from the aerial parts of Artemisia abrotanum L. that recently grown in Iraq.Methods: The essential oil of A. abrotanum was extracted by hydrodistillation using Clevenger apparatus. This essential oil was tested for antimicrobial activity of five different pathogenic microorganisms (Gram-positive [Staphylococcus aureus and Bacillus subtilis] and Gram-negative [Salmonella typhi and Escherichia coli] bacterial strains) and fungi: Candida albicans using diffusion well agar method. Furthermore, this essential oil was tested for cytotoxic activity using rhabdomyosarcoma cell line, and the growth or inhibition of cancer cells was measured by MTT method.Results: The obtained results show that the antibacterial activity for A. abrotanum against S. aureus was at concentrations 40, 25, and15 μl with minimum inhibitory concentrations of 20 mm, while it showed antibacterial activity against E. coli for four different concentrations of 40, 25, 15, and10 μl with inhibition zone of 16, 12, 14, and 10 mm, respectively, and it showed antifungal activity against C. albicans at four concentrations 40, 25, 15, and10 μl with inhibition zone of 18, 24, 26, and 30 mm, respectively. The cytotoxic activity of the extracted essential oil was showed that the three concentrations of the extract (25, 50, and 100 μg/ml) were all lower significantly as compared to dimethyl sulfoxide group. A significant difference was seen for group 25 with both groups 50 and 100, but no significant difference was seen between the two later. Finally, the antimicrobial and anticancer activity of this plant could be due to its essential oil constituents: Borneol, cymene, camphor, terpineol, eucalyptol, and aromadendrene.Conclusion: The essential oil of A. abrotanum L. has a potent antimicrobial and anticancer effect against the tested microbial organisms and the cancer cells.
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Aljubory, Ibrahim, Thamer Jasiem, and Sara Baderden. "Agriculture, active compounds investigation of cola herb (Artemisia abrotanum L.) recently introduced in Iraq." National Journal of Physiology, Pharmacy and Pharmacology 7, no. 4 (2017): 1. http://dx.doi.org/10.5455/njppp.2017.7.1029002012017.

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O., A. Коrablova, B. Rakhmetov D., I. Shanaida M., et al. "The content of macro- and microelements in plants of the genus Artemisia under conditions of introduction in the M. M. Gryshko National Botanical Garden of the NAS of Ukraine." Plant varieties studying and protection 17, no. 3 (2021): 199–209. https://doi.org/10.21498/2518-1017.17.3.2021.242983.

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<strong>Purpose.</strong>&nbsp;To determine mineral composition of plants of species of the genus&nbsp;<em>Artemisia</em>&nbsp;(<em>A. dracunculus</em>&nbsp;L.,&nbsp;<em>A. abrotanum</em>&nbsp;L. and&nbsp;<em>A. argyi</em>&nbsp;H.L&eacute;v. &amp; Vaniot) to determine the possibility of their safe use in the food and pharmaceutical industries of Ukraine. <strong>Methods.</strong>&nbsp;X‑ray fluorescence method for determining the elemental composition of plant raw materials. <strong>Results.</strong>&nbsp;The content of mineral elements in plants of the genus&nbsp;<em>Artemisia</em>&nbsp;was determined depending on their ability to absorb elements from the soil and accumulate in the roots and organs of the aerial part was determined. The quantitative content of 21 macro- and microelements was established, and some peculiarities of their migration and distribution in the soil &ndash; roots &ndash; plant system were revealed. In particular, the aerial part of the studied plants contains K, Fe, Cu, Zn and Mn, which are the most important elements in the life of the plant organism. The content of mesoelements Ca and S is quite high. The amount of toxic elements Pb, Sr and Zr in plants is insignificant. Elements K and S accumulate in the aerial part. The content of elements in the aerial part of plants by decreasing their concentration can be represented in the form of the following series: for&nbsp;<em>Artemisia dracunculus</em>&nbsp;&ndash; S&gt; K&gt; Ca&gt; Cl&gt; Fe&gt; Sr&gt; Zn&gt; Mn&gt; Cu&gt; Zr&gt; Rb&gt; Br&gt; Cr; for&nbsp;<em>A. abrotanum</em>&nbsp;&ndash; K&gt; Ca&gt; S&gt; Cl&gt; Fe&gt; Zn&gt; Sr&gt; Mn&gt; Cu&gt; Br&gt; Cr&gt; Co&gt; Zr&gt; Rb&gt; Ni; for&nbsp;<em>A. argyi</em>&nbsp;&ndash; K&gt; Ca&gt; S&gt; Fe&gt; Cl&gt; Sr&gt; Zn&gt; Mn&gt; Co&gt; Zr&gt; Cu&gt; Rb&gt; Br&gt; Se. The content of toxic elements in the studied plants was lower than the maximum allowable concentrations for plant raw materials and food. <strong>Conclusions.</strong>&nbsp;For the first time under conditions of introduction in the M.&nbsp;M.&nbsp;Gryshko National Botanical Garden of the NAS of Ukraine in the plants&nbsp;<em>Artemisia dracunculus</em>,<em>&nbsp;A. abrotanum</em>&nbsp;and&nbsp;<em>A. argyi</em>&nbsp;the content of macro- and microelements, which are directly related to the metabolism of biologically active compounds, was determined. The peculiarities of their distribution by plant organs during the transition from soil to aboveground mass have been clarified. The obtained results can be used to evaluate and compare the quality of plant raw materials of the genus&nbsp;<em>Artemisia</em>, to determine the pharmacological properties of these plants associated with some elements of the mineral composition, and their use in the medical and food industries. The obtained data have both scientific and practical significance in the selection of economically valuable plant species for the enrichment of the cultivated flora of Ukraine.
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S, Mugendhiran. "Asteraceae Plants used in Homoeopathic System of Medicine, Cultivated in the Center of Medicinal Plants Research in Homoeopathy (CMPRH), Emerald, the Nilgiris, Tamil Nadu." International Journal of Pharmacognosy & Chinese Medicine 5, no. 1 (2021): 1–11. http://dx.doi.org/10.23880/ipcm-16000217.

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The objective of the present study is to survey and document of homeopathic medicinal plants cultivated in the Center of Medicinal Plants Research in Homoeopathy (CMPRH), Emerald, Nilgiris District, Tamil Nadu, India. To prepare the documentation of homoeopathic Medicinal plants of Asteraceae in the Nilgiris District, the present study was conducted during the year 2019–2020. The plants collected were pressed, poisoned, mounted, and stitched on herbarium sheets and deposited at the Centre of Medicinal Plants Research in Homoeopathy herbarium (Acronym SMPRGH). The present study deals with the 29 species belonging to 26 genera of Asteraceae family viz. Achillea millefolium L., Anthemis nobilis L., Artemisia abrotanum L., Artemisia dracunculus L., Artemisia annua L., Bellis perennis L., Calendula officinalis L., Cichorium intybus L., Chrysanthemum parthenium L., Cynara scolymus L., Echinacea purpurea L., Eclipta prostrata (L.)L., Erigeron canadensis L., Galinsoga parviflora Cav., Gnaphalium polycepalum L., Helianthus annuus L., Lactuca sativa L., Leucanthemum vulgare (Vahill.) Lam., Matricaria chamomilla L., Parthenium hysterophorus L., Senecio cineraria DC., Sigesbeckia orientalis L., Silybum marianum (L) Gaertner., Solidago virgaurea L., Stevia rebaudiana (Bertoni) Bertoni., Taraxacum officinnale Wigg. Vernonia anthelmintica (L.)Willd., Xanthium indicum Koenig and Xanthium spinosum L. The present article gives the scientific name, common name, homeopathic drug name, original author citation, English name, phenology, distribution, short description, and part of plant used for preparing homoeopathic medicine. Details such as indigenous or exotic and uses are also given. Reported 29 homoeopathic medicinal plants are used in homoeopathic medicinal system to treat various diseases. Present study also reveals the importance of conservation and sustainable utilization. The documented information is useful for Homeopathic practitioners, scientists, drug developers, medicinal plant enterprises and other scientific bodies which deal with isolation of active ingredients for effective treatment.
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Nikitin, Evgeny, Igor Fitsev, Anastasia Egorova, et al. "Five Different Artemisia L. Species Ethanol Extracts’ Phytochemical Composition and Their Antimicrobial and Nematocide Activity." International Journal of Molecular Sciences 24, no. 18 (2023): 14372. http://dx.doi.org/10.3390/ijms241814372.

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Among the plants that exhibit significant or established pharmacological activity, the genus Artemisia L. deserves special attention. This genus comprises over 500 species belonging to the largest Asteraceae family. Our study aimed at providing a comprehensive evaluation of the phytochemical composition of the ethanol extracts of five different Artemisia L. species (collected from the southwest of the Russian Federation) and their antimicrobial and nematocide activity as follows: A. annua cv. Novichok., A. dracunculus cv. Smaragd, A. santonica cv. Citral, A. abrotanum cv. Euxin, and A. scoparia cv. Tavrida. The study of the ethanol extracts of the five different Artemisia L. species using the methods of gas chromatography–mass spectrometry (GC–MS) and high-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (HPLC–MS/MS) allowed establishing their phytochemical profile. The obtained data on the of five different Artemisia L. species ethanol extracts’ phytochemical composition were used to predict the antibacterial and antifungal activity against phytopathogenic microorganisms and nematocidal activity against the free-living soil nematode Caenorhabditis elegans. The major compounds found in the composition of the Artemisia L. ethanol extracts were monoterpenes, sesquiterpenes, flavonoids, flavonoid glycosides, coumarins, and phenolic acids. The antibacterial and antifungal activity of the extracts began to manifest at a concentration of 150 µg/mL. The A. dracunculus cv. Smaragd extract had a selective effect against Gram-positive R. iranicus and B. subtilis bacteria, whereas the A. scoparia cv. Tavrida extract had a selective effect against Gram-negative A. tumefaciens and X. arboricola bacteria and A. solani, R. solani and F. graminearum fungi. The A. annua cv. Novichok, A. dracunculus cv. Smaragd, and A. santonica cv. Citral extracts in the concentration range of 31.3–1000 µg/mL caused the death of nematodes. It was established that A. annua cv. Novichok affects the UNC-63 protein, the molecular target of which is the nicotine receptor of the N-subtype.
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EL-Hefny, Mervat, and Abeer A. Mohamed. "Enhancing the Growth of Artemisia abrotanum by Magnesium and Tropaeolum majus Extract in a Field Experiment Along with the Antibacterial Activity of the Isolated Essential Oils." Horticulturae 11, no. 3 (2025): 328. https://doi.org/10.3390/horticulturae11030328.

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Enhancing the growth and productivity of ornamental and horticultural plants is a major function of plant extracts and macronutrient elements. The growth properties of Artemisia abrotanum plants were evaluated in two successive seasons as affected by the magnesium (Mg) fertilizer added to the soil in the form of magnesium sulfate at four concentrations of 0 (as a control), 4, 6, and 8 g/L as well as Tropaeolum majus aqueous leaf extract (ALE) at concentrations of 0 (as a control), 4, 6, and 8 g/L as a foliar application. The chemical components of A. abrotanum essential oils (EOs) were analyzed using the gas chromatography–mass spectrometry (GC-MS) apparatus. The studied parameters, including plant height, total fresh weight, number of branches/plant, EO percentages, chlorophyll-a content, chlorophyll-b content, and carotenoid content, were enhanced by the application of Mg or T. majus ALE or their combinations. The highest plant heights, 48.83 cm, and 48.5 cm, were observed in the plants treated with Mg (8 g/L)+T. majus ALE (8 g/L) and Mg (6 g/L)+T. majus ALE (4 g/L), in both seasons, respectively. The highest values of total fresh weight, 54.80 and 60.59 g, were recorded in plants treated with Mg (8 g/L)+T. majus ALE (4 g/L) and Mg (8 g/L)+T. majus ALE (4 g/L), in both seasons, respectively. The highest number of branches/plant, 60.33 and 73.33, were measured in plants treated with Mg (8 g/L) + T. majus LAE (8 g/L), in both seasons, respectively. The highest EO percentages, 0.477% and 0.64%, were measured in plants treated with Mg (8 g/L)+T. majus ALE (8 g/L), in both seasons, respectively. The total fresh weight in both seasons (r = 0.96), the number of branches/plant in both seasons (r = 0.97), the number of branches/plant in the first season, and the number of branches/plant in both seasons (r = 0.96), the total fresh weight in the second season and the number of branches/plant in the first season (r = 0.95) and the second season (r = 0.94), and the number of branches/plant and the carotenoids in the first season (r = 0.90) were all found to be significantly and positively correlated. The major compounds in the EOs were 7-methoxy-4-methylcoumarin (4-methylherniarin), cedrol, endo-borneol, and 7-epi-silphiperfol-5-ene. The antibacterial activity of the EOs was evaluated against the growth of Pectobacterium atrosepticum and Pectobacterium carotovorum subsp. carotovorum, which causes soft rot of potato tubers. The EOs were found to be effective against P. carotovorum subsp. carotovorum with the inhibition zones ranging from 1 to 5 mm at the concentration of 100 μg/mL, and no inhibitions were found against P. atrosepticum at the studied concentrations. The minimum inhibitory concentration against P. carotovorum subsp. carotovorum was found at 75 μg/mL. In conclusion, using the combination treatments of Mg and T. majus ALE is highly suggested to enhance the growth of A. abrotanum plants.
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Remberg, P., L. Björk, T. Hedner, and O. Sterner. "Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis." Phytomedicine 11, no. 1 (2004): 36–42. http://dx.doi.org/10.1078/0944-7113-00350.

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Almahdawy, Sarah S., Ibrahim S. Abbas, and Ashour H. Dawood. "Analysis of the essential oil extract from the aerial parts of southernwood herb (Artemisia abrotanum L.) that grown in Iraq by GC/MS." Al Mustansiriyah Journal of Pharmaceutical Sciences 17, no. 1 (2018): 6. http://dx.doi.org/10.32947/ajps.v17i1.68.

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Objective: this research is to identify the chemical composition of essential oil of the aerial parts of A.abrotanum L. that grown in Iraq and used recently only for decorative purpose.Method: After collection of the aerial parts the essential oil extracted by hydro-distillation using Clevenger apparatus, then the oil are analyzed by GC/MS.Result: The obtained results show the presence of 14 compounds. The most important constituents are: Eucalyptol (1, 8-cineole), O-cymene, Camphor, Terpineol, Borneol, Longipinocarvone, Limonene, and Aromadendrene.Conclusion: This study analyzes the chemical constituents of the essential oil of A.abrotanum. The essential oil extracted by hydrodistillation then analyzed by GC/MS. 14 Compounds were identified. Due to good result obtained from the essential oil from this plant so further studies chemically and clinically of the active compounds is required.
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Selmi, Mejda, Latifa Lassoued, Badra Bannour, et al. "Therapeutic effect of herbal infusion on abnormal uterine bleeding: interventional non-randomized pilot study." F1000Research 11 (September 28, 2022): 1116. http://dx.doi.org/10.12688/f1000research.122435.1.

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Background: Abnormal uterine bleeding-menometrorrhagia due to uterine myomas is a health problem affecting women’s quality of life and it is considered a frequent cause of emergency visits for women. If first line medication fails to treat symptoms, surgical procedures, such as hysterectomy could be indicated, which could interfere with women's physical, social, emotional, and material quality of life. The purpose of this pilot study was to investigate the effect of a mixture of two medicinal plants, Mentha pulegium L and Artemisia abrotanum L, on 13 women with menometrorrhagia, who were candidates for hysterectomy. Methods: The herbs were taken as a tea infusion by the oral route. A total of 5 g of the dried aerial parts of the mixture were added to 100 ml of boiling water and the tea infusion was taken three times a day starting from the onset of menstruation for three consecutive days, and it was repeated for three consecutive months. Results: The study results showed that 10 out of the 13 women involved avoided the surgical procedures. The mean number of bleeding days declined from 11.50 (±3.77) at baseline to 7.60 (±2.11) (p=0.01). Participants confirmed a change in the bleeding intensity, regularization of their menstrual cycle, and improvement in their quality of life. Conclusions: This preliminary study explores a new approach to treat abnormal uterine bleeding- menometrorrhagia, based on tea infusion consumption of a mixture of two medicinal herbs, and it paves the way for future studies. Trial registration: This study is registered with ClinicalTrials.gov NCT05406960 (07/06/2022).
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Saunoriūtė, Sandra, Ona Ragažinskienė, Liudas Ivanauskas, and Mindaugas Marksa. "Essential oil composition of Artemisia abrotanum L. during different vegetation stages in Lithuania." Chemija 31, no. 1 (2020). http://dx.doi.org/10.6001/chemija.v31i1.4171.

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Artemisia abrotanum L. was introduced in the Middle of Lithuania Collection of Spice–Melliferous Plants of the Scientific Sector of Medicinal and Aromatic Plants of the Botanical Garden ex situ at Vytautas Magnus University since 1980. The object of investigation was Artemisiae abrotani herba of Artemisia abrotanum L. All samples were collected at different vegetation stages: growth and leaf production, flower bud development, the beginning of flowering, massive flowering and the end of flowering. Essential oils were obtained by hydrodistillation. The chemical composition of the essential oils of Artemisiae abrotani herba was studied by GC/MS in the Department of Analytical and Toxicological Chemistry at the Lithuanian University of Health Science in 2018–2019. Fifty-six compounds of the oil were identified, of which (+)-piperitone was the major component (20.38–38.48%). The data in this study showed a remarkable quantitative variation of constituents in the essential oils. The highest content and diversity of compounds was determined during the flower bud development stage. Sixty identified compounds in this stage reached 76.6% of the identified oil content. The highest concentration of this compound (38.48%) was detected at the end of the flowering vegetation stage and the lowest amount (20.38%) was found during the growth and leaf production. Among the other major compounds were (+)-piperitone, 1,4-cineole, lavandulyl butyrate, aromandendrene and isogermacrene D.
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Selmi, Mejda, Latifa Lassoued, Chahra Chbili, Maha Ben Fredj, and Ridha Charfeddin. "Nutritional value and therapeutic effect of Mentha pulegium L. and Artemisia abrotanum L." Journal of Medicinal Herbs and Ethnomedicine, October 12, 2022, 16–20. http://dx.doi.org/10.25081/jmhe.2022.v8.7559.

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This work is an informative study investigated the nutrient contents and the antioxidant activity of Mentha pulegium L. and Artemisia abrotanum L. two plants largely used in North African traditional medicine as well as in pharmaceutical and agro-alimentary industries. These plants have been used as herbal tea, or powder in herbal remedies, to treat painful menstruation, and gastrointestinal disorders. Recently they were extensively used during the pandemic of Covid-19. Results revealed that both plants were not, only, a good source of essential minerals, like Calcium, Iron, and Magnesium. But they were also rich sources of crude fibre and protein. Vitamin C amount was found 180.94 ±3.01 mg/g100g, with an IC50 value 54.45±25.53 μg/mL 10-1 in M. pulegium and 171.64±3.0 mg/100g with IC50 value 60.61± 19.71 μg/mL 10-1 in A. abrotanum. The antioxidant study showed a high activity that paves the way for the possibility of new health-related uses.
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Жанжаксина, А., Ж. Ибатаев та А. Аширбек. "ARTEMISIA PROCERIFORMIS L. (ARTEMISIA ABROTANUM): ОБЗОР ЛИТЕРАТУРЫ ПО ХИМИЧЕСКОМУ СОСТАВУ И БИОЛОГИЧЕСКОЙ АКТИВНОСТИ". SERIES CHEMISTRY AND TECHNOLOGY, № 2 (22 червня 2025). https://doi.org/10.32014/2025.2518-1491.282.

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Род Artemisia является крупнейшим родом растений, насчитывающим около 500 видов, который имеет потенциальные источники новых природных биологически активных продуктов и химических структур. Artemisia proceriformis L. является одним из наиболее известных лекарственных видов этого рода и занимает важное место в европейской и азиатской медицине.Целью данного исследования является обзор химического состава и биологической активности A. proceriformis. Эти материалы могут помочь упростить дальнейшие исследования этого вида растений и будут полезны для поиска новых биологически активных соединений.В данном обзоре мы собрали данные недавней литературы по составам эфирных масел и экстрактов и их биологической активности. Эти данные были получены из международных баз данных, таких как SciFinder и PubChem.Компонентный состав эфирного масла A. proceriformis варьируется в зависимости от места произрастания и сбора. Однако было установлено, что основными компонентами этого эфирного масла являются α-туйон, β-туйон, 1,8-цинеол, 1,4-цинеол, аромадендрен, изогермакрен D, даванон, 1-терпинеол, транс-пиперитол, 2-гидрокси-1,8-цинеол, β-эудесмол и камфора. Также, согласно литературным данным, это эфирное масло проявило антимикробную, противораковую и антиоксидантную активность. Основные вторичные метаболиты A. proceriformis относятся к группе флавоноидов, сесквитерпеновых лактонов, фенольных кислот, кумаринов и благодаря этому могут проявлять различные виды биоактивности. В данном обзоре мы объединили данные в таблицу и сделали эти данные более доступными.В результате обзора можно сделать вывод, что данные о компонентном составе экстрактов A. proceriformis, произрастающего в Казахстане, отсутствуют.
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"Detection of terpenes of Iraqi Artemisia abrotanum L. by GC/MS in hexane extract." Al Mustansiriyah Journal of Pharmaceutical Sciences, November 1, 2019, 239–48. http://dx.doi.org/10.32947/ajps.19.04.0434.

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Artemisia abrotanum L. is recently introduced plant in Iraq, in this study we conducted GS/MS for detection of terpene that are group of constituents abundant in this species qualitatively and quantatively. We used hexane extract for the detection depending on the like dissolve like proce- dure of extraction since they are mostly nonpolar compounds, they dissolve in nonpolar solvent like hexane thus the extraction procedure is conducted with this solvent. New compound was detected with hexane extract that wasn't present in previous studies.
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Alihodzic, Adna, Jimmy Davis, Christopher Roberts, Sally Henrie, and Mark Bolyard. "Production of secondary metabolites in regenerated Southern wormwood (Artemisia abrotanum L.) under various experimental conditions." In Vitro Cellular & Developmental Biology - Plant, September 28, 2023. http://dx.doi.org/10.1007/s11627-023-10382-0.

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Yurchyshyn, O. І. "SEARCH FOR BIOLOGICALLY ACTUVE SUBSTANCES WITH ANTIMICROBIAL AND ANTIBIOTIC POTENTIATING PROPERTIES AMOUNG MEMBERS OF THE GENUS ARTEMISIA AGAINTS THE MAIN PATHOGENS OF INFECTIOUS SKIN LESIONS." Art of Medicine, April 5, 2021, 84–89. http://dx.doi.org/10.21802/artm.2021.1.17.84.

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Abstract. Active components of the genus Artemisia show a wide range of antimicrobial effect against most bacterial pathogens. In addition, artemisin isolated from wormwood is used to treat chloroquine-resistant malaria. Antimicrobial and antibiotic-potentiating effects of eight aqueous ethanolic extracts (40 %, 70 % and 90 %) aerial part of the genus Artemisia aqueous against S. aureus and S. epidermidis strains with various types of resistance to macrolides, lincosamides, tetracyclines and fluoroquinolones isolated from outpatients with different forms of pyoderma have been researched with agar diffusion micromethod. Determination of effective antimicrobial concentrations of antimicrobials and test extracts against staphylococci have been performed with serial dilutions micromethod. The statistical program "Statistica", computer programs UTHSCSA Image Tool 3.0 and Microsoft Office Excel 2016 have been used for statistical processing of microbiological research results. The pronounced antimicrobial effect of the wormwood extract Artemisia dracunculus L. (MIC 125.0 - 250.0 μg/ml) against all S. aureus and S. epidermidis test strains has been established. Other studied extracts showed much weaker antimicrobial effect (MIC 1000.0 - 1500.0 μg/ml). It was found that the species of staphylococci and the phenotype of resistance of test strains do not affect antimicrobial activity of the studied extracts. We have found that there is no clear сorrelation between antimicrobial properties of the studied extracts and the phenotype of resistance of staphylococci test-strains. Extracts were equally effective against staphylococcal strains with low level of resistance by efflux of antimicrobial drug and skin isolates with chromosomal resistance. The greatest resistance to BAC of the studied extracts was showed by test strains with a high level of resistance to antibiotics of MLS-group and tetracycline, exhibiting sensitivity only to tarragon wormwood.&#x0D; Active components of 70, 90 % common mugwort extract Artemisia vulgaris L. (increase of the inhibition zone up to 117 – 142 %, p&lt;0.05) and southern wormwood extract (increase of the inhibition zone up to 50 – 59 % and 74 – 122 %, respectively, p&lt;0.05) showed dose-dependent synergistic interaction with erythromycin. Common mugwort extract (70 %) showed synergistic interaction with ¼ MIC of tetracycline (increase of the inhibition zone up to 100 %) against strains with combined resistance to all studied antimicrobials. For the study we used crude total extracts of medicinal plants (40 %, 70 % and 90 % ethanol), so we expect their significantly higher antimicrobial effect against staphylococcal strains while optimizing the extraction process and subsequent purification. It should be noted that 90 % aqueous ethanol extracts showed significantly better antimicrobial properties compared to 40 % and 70 % extracts. Active compounds of tarragon wormwood Artemisia dracunculus L. extract show pronounced antimicrobial effect against S. aureus and S. epidermidis strains, the main causative agents of infectious skin lesions, with different types of resistance to macrolides, lincosamides, tetracyclines and fluoroquinolones. Dose-dependent synergistic interaction with macrolides of common mugwort Artemisia vulgaris L. extracts and southern wormwood Artemisia abrotanum L. extract with macrolides (erythromycin) and tetracycline has been revealed.
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"Cytotoxicityassay of ethyl acetate extract and isolated rutin and quercttin of Iraqi cultivated Artemisia abrotanum L." International Journal of Pharmaceutical Research 12, no. 01 (2020). http://dx.doi.org/10.31838/ijpr/2020.12.01.178.

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OSMANLIOĞLU DAĞ, Ş. Rumeysa, Murat KÜRŞAT, Ayşe Mine GENÇLER ÖZKAN, and İffet İrem ÇANKAYA. "Türkiye'de Yetişen Beş Artemisia L. Türünün Gövde Ve Yaprak Anatomisinin İncelenmesia." Türk Tarım ve Doğa Bilimleri Dergisi, August 10, 2023. http://dx.doi.org/10.30910/turkjans.1243385.

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In this study, it is aimed to make anatomical analysis of five different Artemisia L. species (A. absinthium L., A. annua L., A. abrotanum L., A. incana (L.) Druce, A. tournefortiana Rchb.) grown in Turkey and contribute to the definition of this genus, which has some taxonomic problems. The materials for anatomical study were preserved in 70% alcohol. Free hand cross sections were taken using sharp razor blades, stained and mounted in Sartur Reagent and Chloralhydrate (50%) solution. Anatomical structures of the stem and leaf of selected species were examined under the light microscope. Their detailed structures were illustrated with photographs. Results have shown that stem and leaf anatomical features of the Asteraceae family are mostly shared by all species. However, some characters could be considered species-specific. In cross- sections, the stems of all studied species have more or less irregular rounded shapes, but prominent ribs containing collenchyma tissue could be noticed only in A. annua stem. The leaves of A. absinthium and A. incana were covered by glandular and densely T-shaped non--glandular trichomes on both sides however, A. tournefortiana had no hair at all. There were highly apparent secretory canals located in both the stem (next to the endodermal cells) and the leaf (near to xylem) of A. tournefortiana. The anatomical structure of leaves and stems of A. tournefortiana and A. incana growing in Turkey was demonstrated for the first time. Our results revealed that the studied species are anatomically distinguishable from each other and also provided valuable features for better species identification and contribute to the anatomy of the genus Artemisia.
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CANSEVER, İslam, and Özlem SÖĞÜT. "Determination of Total Protein and Free Amino Acid Content of Artemisia abrotanum L. in the Blooming and Pre-Blooming Period." Bezmialem Science, March 25, 2022, 0. http://dx.doi.org/10.14235/bas.galenos.2021.6688.

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Svanberg, Ingvar, and Erik de Vahl. "“It may also have prevented churchgoers from falling asleep”: southernwood, Artemisia abrotanum L. (fam. Asteraceae), in the church bouquet, and its contemporary presence as a heritage plant in Sweden." Journal of Ethnobiology and Ethnomedicine 16, no. 1 (2020). http://dx.doi.org/10.1186/s13002-020-00401-4.

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