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1

КУРМАНБАЕВА, М. С., А. Р. ИЗБАЙ та Ж. Б. КАЛДЫБАЕВА. "ИССЛЕДОВАНИЯ КОМПОНЕНТНОГО СОСТАВА РАСТЕНИЯ ARTEMISIA ANNUA L. И ЕГО АНТИМИКРОБНОЙ АКТИВНОСТИ". Farmaciâ Kazahstana, № 3 (15 липня 2023): 108–17. http://dx.doi.org/10.53511/pharmkaz.2023.40.68.016.

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Полынь однолетняя (Artemisia annua L.) семейства (Asteraceae) — травянистое однолетнее растение, которое используется народной медицине уже более двух тысяч лет. Artemisia annua L. имеет антиоксидантные, противовоспалительные, противоболевые, седативные, антибактериальные, противовирусные, гиполипидемические, противоопухолевые свойства. Во многих странах полынь однолетняя используется в качестве официального противомалярийного и противолейшманиального средства. Ее иммуносупрессивные, противоревматические, противозачаточные и антихолинергические свойства являются перспективными. Артемизинин, се
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2

Tao, Ali, Xuehua Feng, Zurong Song, Bo Hu, Huan You, and Ruilin Wang. "Study on the Antilipidemic Activity of Artemisia Annua Aqueous Extract." E3S Web of Conferences 185 (2020): 03050. http://dx.doi.org/10.1051/e3sconf/202018503050.

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Artemisia annua is an annual herb, which is a traditional Chinese medicine in China. The high water soluble artemisinin derivative extracted from Artemisia annua is Artemisia annua water extract. In this experiment, the modeling method is used, and the Artemisia annua water extract is used alone or in combination with other lipid-lowering drugs. Finally, the results showed that the effect of the combination of drugs was better than that of Artemisia annua water extract alone, and the effect of the drug ratio of 1:1 was the best. It can significantly reduce the content of triglyceride in serum
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3

Nikolova, Milena, Renata Gevrenova, and Stephanka Ivancheva. "High-performance liquid chromatographic separation of surface flavonoid aglycones in Artemistia annua L. and Artemisia vulgaris L." Journal of the Serbian Chemical Society 69, no. 7 (2004): 571–74. http://dx.doi.org/10.2298/jsc0407571n.

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External flavonoid aglycones from Artemisia annua L. and Artemisia vulgaris L. were analyzed by the HPLC method. The mobile phase was composed of t-butanol-methanol- 20 mmol l-1 phosphate buffer, pH 3.22. The linear gradient elution method within 22 min was applied. The main aglycones in A. annua and A. vulgaris are methyl ethers of quercetagetin and quercetin. Quercetagetin 3,6,7-trimethyl ether in A. annua and quercetin 3,7,3?-trimethyl ether in A. vulgaris are the most abundant compounds.
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4

Asqarov, Ibrohim Rahmonovich, and Obidjon Shaxabidinovich Abdulloev. "AN IMPROVED METHOD FOR THE ISOLATION OF ARTEMISININ FROM ANNUAL WORMWOOD (ARTEMISIA ANNUA L.) GROWING IN UZBEKISTAN." Scientific Journal Fergana State University 1, no. 1 (2022): 86–89. https://doi.org/10.5281/zenodo.6698187.

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The chemical composition of representatives of the plant Artemisia annua L. in different geographical regions, in particular the amount of artemisinin, was studied. However, the chemical composition of its representatives growing in Uzbekistan has not been studied. The aim of this study was to isolate and quantify artemisinin from the plant Artemisia annua L. in Uzbekistan, especially in the Ferghana Valley.The extraction of artemisinin from the plant Artemisia annua L. in organic solvents, thin layer and column chromatography, IR, and mass spectrometry were used to determine the physicochemic
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5

Liu, Rong, Jinbiao Wang, Mu Xiao, Xiewang Gao, Jin Chen, and Yanjiao Dai. "AaCOI1, Encoding a CORONATINE INSENSITIVE 1-Like Protein of Artemisia annua L., Is Involved in Development, Defense, and Anthocyanin Synthesis." Genes 11, no. 2 (2020): 221. http://dx.doi.org/10.3390/genes11020221.

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Artemisia annua is an important medicinal plant producing the majority of the antimalarial compound artemisinin. Jasmonates are potent inducers of artemisinin accumulation in Artemisisa annua plants. As the receptor of jasmonates, the F-box protein COI1 is critical to the JA signaling required for plant development, defense, and metabolic homeostasis. AaCOI1 from Artemisia annua, homologous to Arabidopsis AtCOI1, encodes a F-box protein located in the nuclei. Expressional profiles of the AaCOI1 in the root, stem, leaves, and inflorescence was investigated. The mRNA abundance of AaCOI1 was the
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6

SHAHRAJABIAN, Mohamad H., Wenli SUN, and Qi CHENG. "Exploring Artemisia annua L., artemisinin and its derivatives, from traditional Chinese wonder medicinal science." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 48, no. 4 (2020): 1719–41. http://dx.doi.org/10.15835/nbha48412002.

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Artemisia annua L. (Chinese wormwood herb, Asteraceae) synthesizes artemisinin, which is known as qinghaosu, considers as a unique sesquiterpene endoperoxide lactone. In traditional Chinese medicine, it has been used for the treatment of fevers and haemorrhoides. More researches on Artemisia annua L. and its derivatives, especially artemisinin and other metabolites will help to increase the knowledge and value of A. annua and its constituents. Phenolics from Artemisia annua consists of coumarins, flavones, flavonols, phenolic acids, and miscellaneous. Artemisinin has attracted much attention f
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Shevchuk, O. M., L. A. Logvinenko, T. D. Mezenova, and D. A. Konovalov. "Artemisia scoparia Waldst. & Kit. and Artemisia annua L. in the collection of aromatic and medicinal plants of the Nikitsky Botanical Garden." E3S Web of Conferences 254 (2021): 06011. http://dx.doi.org/10.1051/e3sconf/202125406011.

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The article presents the results of the study of Artemisia scoparia Waldst. & Kit. (paniculate wormwood) and Artemisia annua L. (annual wormwood), grown in the Nikitsky Botanical Garden - National Scientific Center of the Russian Academy of Sciences (NBG-NSC RAS). The Nikitsky Botanical Garden is the originator of Artemisia scoparia cv. varieties. Tavrida and Artemisia annua cv. Novichok, which are included in the Register of varieties of Russia allowed for distribution in the south of Russia. Both varieties are of interest as resource varieties having a significant potential for use as so
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Andani, Apri, Yudhy Harini Bertham, and Abimanyu Dipo Nusantara. "PERSEPSI MASYARAKAT TANI TERHADAP PROGRAM PEMBERDAYAAN PETANI MELALUI SOSIALISASI TANAMAN OBAT Artemisia annua L. DI KABUPATEN KEPAHIANG PROVINSI BENGKULU." Humanus 13, no. 2 (2014): 107. http://dx.doi.org/10.24036/jh.v13i2.4720.

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The purpose of this study is to determine the level of farmers’ perception towards empowerment program of farmers through public introduction of Artemisia annua L. medicinal plants in Kepahiang District Bengkulu Province. The location is intentionally determined by considering the geographical eligibility factor for the growth and development of the plant Artemisia annua L., which is more than 1000 meters above sea level. The study is conducted in three villages; Bandung Baru, Tangsi Duren, and Sukasari. In this study, respondents are deliberately determined on the farmers’ willingness to part
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9

MUZAMIL, MOHIUDDIN, AFZAL MIR RAYEES, PRAVEEN SALMA, and GULFISHAN MOHD. "EFFECT OF LEAD (PB) ON PHYSICOCHEMICAL CHARACTERISTICS OF ARTEMISIA ANNUA L." Seybold Report Journal 18, no. 09 (2023): 677–90. https://doi.org/10.5281/zenodo.8379186.

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<strong>Abstract</strong> <em>Artemisia annua</em> L., often known as sweet wormwood, sweet Annie, sweet sagewort, and annual wormwood, is a widespread species of wormwood that originated in temperate Asia but has since spread naturally around the world. It is a member of the Asteraceae family. Chinese medicinal plant <em>Artemisia annua</em> L.is renowned for its antiplasmodial, antirheumatic, and anticancer effects. Currently, <em>Artemisia annua</em>&nbsp; L.is the source of artemisinin and semi-synthetic artemisinin derivatives, such as dihydroartemisinin, artesunate, artemether, and artee
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10

Auguste-Denise Mambé BOYE, Serge Kouadio N'GONIAN, and Elie Konan YOBOUET. "Trial of the use of aqueous extracts based on Artemisia annua L in the protection of soilless tomato crop (Solanum lycopersicum L. 1753) in Daloa (Central-Western Côte d'Ivoire)." International Journal of Science and Research Archive 7, no. 1 (2022): 175–85. http://dx.doi.org/10.30574/ijsra.2022.7.1.0194.

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Tomato (Solanum lycopercicum L) is one of the most cultivated crops in Côte d'Ivoire. However, its production is confronted with enormous constraints, especially the damage caused by pathogens and vectors of certain diseases. Faced with this damage, most growers resort to chemical products that are harmful to the environment, the user and consumers. Therefore, it becomes necessary to use the extract of Artemisia annua as a biopesticide in the control of diseases and pests of tomato crop in the field. The trial consisted in setting up an above ground tomato crop and then formulating a biopestic
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11

Ding, Fangyu, Tian Ma, Mengmeng Hao, et al. "Mapping Worldwide Environmental Suitability for Artemisia annua L." Sustainability 12, no. 4 (2020): 1309. http://dx.doi.org/10.3390/su12041309.

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Artemisinin, which is isolated from the naturally occurring plant Artemisia annua L. (A. annua; Qinghao in traditional Chinese medicine), is considered to be the active ingredient in the most effective treatment for malaria. Current malaria eradication plans rely on an affordable and robust supply of artemisinin, resulting in the demand to expand the area of A. annua under cultivation. However, there is no reliable assessment of the potential land resources suitable for planting A. annua at the global scale. By explicitly incorporating the assembled contemporary occurrence records of A. annua
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12

Alam, Pravej, and Thamer H. Albalawi. "In vitro alteration of artemisinin biosynthesis in Artemisia annua L during treatment with methyl jasmonate." Tropical Journal of Pharmaceutical Research 19, no. 1 (2020): 33–37. http://dx.doi.org/10.4314/tjpr.v19i1.5.

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Purpose: To investigate the in vitro effect of methyl jasmonate (MeJA) on artemisinin biosynthesis in Artemisia annua.Method: The effect of two concentrations of MeJA i.e. 2 μm (T2) and 5 μm (T5) on biomass, plant height and artemisinin content of Artemisia annua L. was investigated in vitro in MS medium.Results: Plant height (6.5 ± 1.8 cm), biomass (0.18 ± 0.02 g/plant) and artemisinin content (0.035 ± 0.002 % dry weight) were higher in T5 and T2 treatment groups than in non-treated control plants (C). Artemisinin content, biomass and plant height were positively correlated after 2 - 8 days o
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13

Manalu, Meilina Marsinta, Komar Ruslan Wirasutisna, and Elfahmi Elfahmi. "Produksi Senyawa Metabolit Sekunder Melalui Kultur Jaringan dan Transformasi Genetik Artemisia Annua L." Acta Pharmaceutica Indonesia 37, no. 1 (2012): 23–27. http://dx.doi.org/10.5614/api.v37i1.4035.

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Produksi metabolit sekunder pada tanaman biasanya menghasilkan kadar yang rendah. Metode bioteknologi telah terbuktidapat meningkatkan produksi beberapa metabolit sekunder pada tanaman. Untuk meningkatkan perolehan metabolit sekunder telah digunakan teknik kultur jaringan dan transformasi genetik dengan induksi Agrobacterium rhizogenes. Penelitian ini bertujuan untuk meningkatkan kandungan metabolit sekunder dari kultur kalus dan akar rambut dari tanaman Artemisia annua hasil transformasi genetik menggunakan A. rhizogenes. Kultur kalus dan akar rambut hasil transformasi genetika mengandung sen
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Zayova, Ely Georgieva, Trendafil Atanasov Nedev, Detelina Hristova Petrova, Miroslava Konstantinova Zhiponova, and Ganka Todorova Chaneva. "Efficient protocol for mass micropropagation of Artemisia annua L." GSC Biological and Pharmaceutical Sciences 5, no. 2 (2018): 059–68. https://doi.org/10.5281/zenodo.4305380.

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An efficient protocol for mass micropropagation of&nbsp;<em>Artemisia annua</em>&nbsp;L. was developed. The shoots were&nbsp;<em>in vitro</em>&nbsp;cultivated on a full and half strengths MS supplemented with BAP and IBA for shoot and root induction from stem tip explants. Maximum number of shoots (19.1) with an average shoot height of 3.6 cm was achieved at full MS medium + 1.0 mg/L BAP, after four weeks of cultivation. The best plant rooting (100%), with 7.4 average roots&rsquo; number per explant and average root length of 15.1 cm, was obtained at &frac12; MS medium + 0.1 mg/L IBA + 2.0% su
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15

Kituyi, Lusweti, Samson M. Lutta, and Steve Barasa. "Antimicrobial activity of Artemisia annua L and Aloe barbadense miller plant extracts against Staphylococcus aureus." Journal of Phytopharmacology 12, no. 5 (2023): 295–98. http://dx.doi.org/10.31254/phyto.2023.12503.

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Artemisia annua L. and Aloe barbadense miller are medicinal plants applied in treatment of various diseases. Staphylococcus aureus is a gram-negative bacterium found commonly on the skin and in the environment. Phytochemical are plants secondary metabolites with promising medicinal properties as remedy to limitations associated with the conventional drugs. A study was conducted to investigate the anti-microbial properties of bioactive components from natural leave extracts of Artemisia annua L. and Aloe barbadensis miller obtained from methanolic as extractant against Staphylococcus aureus. Th
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Zhao, Guo-Zhen, Jie Li, Hai-Yu Huang, et al. "Pseudonocardia artemisiae sp. nov., isolated from surface-sterilized Artemisia annua L." International Journal of Systematic and Evolutionary Microbiology 61, no. 5 (2011): 1061–65. http://dx.doi.org/10.1099/ijs.0.021931-0.

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A novel actinomycete strain, designated YIM 63587T, was isolated from surface-sterilized roots of Artemisia annua L. collected from Yunnan province, south-west China. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain YIM 63587T was affiliated to the genus Pseudonocardia. 16S rRNA gene sequence similarities between strain YIM 63587T and type strains of species of the genus Pseudonocardia were 96.6–93.8 %. The diagnostic cell-wall diamino acid in the peptidoglycan layer of strain YIM 63587T was meso-diaminopimelic acid and the whole-cell sugars were arabinose, galactose,
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Dégbé, Mlatovi, Amivi Tété-Bénissan, Françoise Debierre-Grockiego, et al. "Evaluation of Antitoxoplasmic Potential of Selected Antimalarial Medicinal Plants from Togo: Artemisia annua L., Jatropha curcas L., Moringa oleifera Lam., and Sarcocephalus latifolius (Smith) Bruce." International Journal of Biochemistry Research & Review 34, no. 3 (2025): 134–53. https://doi.org/10.9734/ijbcrr/2025/v34i3993.

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Introduction: Toxoplasmosis, a prevalent zoonotic disease, poses significant health challenges, particularly in Togo with high prevalence. Limited public awareness and suboptimal treatments necessitate exploring novel therapeutic avenues. This study investigated Togolese medicinal plants, especially those traditionally used to cure malaria, as potential sources of antitoxoplasmic agents, leveraging ethnobotanical knowledge and scientific validation for accessible drug discovery. Materials and Methods: Phytochemical screening quantified key groups: phenols, tannins, flavonoids, and polysacchari
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Auguste-Denise Mambé BOYE, Elie Konan YOBOUET, and Serge Kouadio N’GONIAN. "Effects of substrates on the emergence and growth of Artemisia annua L. (Asteraceae) in soilless culture in Daloa (West Central Côte d'Ivoire)." International Journal of Science and Research Archive 4, no. 1 (2021): 198–209. http://dx.doi.org/10.30574/ijsra.2021.4.1.0165.

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Artemisia annua is a plant used in traditional Chinese medicine to prevent and treat malaria and other parasitosis. However, the production of Artemisia annua seems to face many problems especially in the germination of grains making it difficult to grow this promising plant. The objective of this work is to contribute to the improvement of the emergence and growth of Artemisia annua in soilless culture. To do so, Artemisia annua seeds were sown in a germinator made of three organic substrates: simple soil, carbonized rice husk soil and soil-compost all supplemented with decomposed chicken dro
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DANGASH, Alka Jagdish, Neeta PANDYA, Ashish BHARILLYA, Ashween JHALA, and Dharamchand JAIN. "Impact of Exogenous Elicitors on Artemisinin Production and Trichome Density in Artemisia annua L. under Subtropical Conditions." Notulae Scientia Biologicae 6, no. 3 (2014): 349–53. http://dx.doi.org/10.15835/nsb639109.

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Artemisinin is a sesquiterpene lactone found in Artemisia annua having many medicinal properties. Therefore the factors affecting trichome initiation are important. In the present study, several strategies have been adapted to increase artemisinin production by treating them with nutrients, hormones and elicitors. Abscisic acid, Gibberellic acid (GA3), a combination of GA3+IAA (Gibberellic acid+indole acetic acid), Chitosan, Methyl jasmonate, Acetyl salicylic acid, Lead acetate, sodium chloride, and Nanozime were sprayed on plant at regular intervals. The glandular trichomes of leaves from Art
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Minda, Daliana, Roxana Ghiulai, Christian Dragos Banciu, et al. "Phytochemical Profile, Antioxidant and Wound Healing Potential of Three Artemisia Species: In Vitro and In Ovo Evaluation." Applied Sciences 12, no. 3 (2022): 1359. http://dx.doi.org/10.3390/app12031359.

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Skin injuries, and especially wounds of chronic nature, can cause a major negative impact on the quality of life. New efficient alternatives are needed for wound healing therapy and herbal products are being investigated due to a high content of natural compounds with promising healing activity. For this purpose, we investigated three Artemisia species, Artemisia absinthium L. (AAb), Artemisia dracunculus L. (ADr) and Artemisia annua L. (AAn). Ethanolic extracts, containing different polyphenolic compounds, elicited strong antioxidant activities in the DPPH assay, comparable to ascorbic acid.
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Hailu, Tilahun, Balcha Abera, and Gabra Mariam. "In vitro Mass Propagation of Artemisia (Artemisia annua L.) cv: Anamed." Plant Tissue Culture and Biotechnology 23, no. 2 (2014): 165–76. http://dx.doi.org/10.3329/ptcb.v23i2.17518.

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An efficient in vitro propagation protocol was developed for anamed (A-3) cultivar of Artemisia annua. Two and 1.5% concentration of NaOCl treatment for 10 and 20 min were found to be optimum for sterilization of shoot tip and nodal explants, respectively. Maximum percentage (98.75 ± 2.50) shoot induction was observed from nodal explants cultured on MS supplemented with 0.8 mg/l BAP + 0.1 mg/l IBA followed by 82.50 ± 2.88% from shoot tip explants on the same medium with 0.8 mg/l TDZ for shoot tip explants. The highest number of shoots (8.05 ± 0.66/explant) was regenerated on MS + 1 mg/l BAP +
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De Magalhães, P. M., B. Pereira, and A. Sartoratto. "YIELDS OF ANTIMALARIAL ARTEMISIA ANNUA L. SPECIES." Acta Horticulturae, no. 629 (January 2004): 421–24. http://dx.doi.org/10.17660/actahortic.2004.629.55.

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Tyagi, B. R., and Ratna Dubey. "Pachytene chromosome morphology of Artemisia annua L." CYTOLOGIA 55, no. 1 (1990): 43–50. http://dx.doi.org/10.1508/cytologia.55.43.

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Takenaka, Yukiko, Satoko Seki, Toyoyuki Nishi, and Takao Tanahashi. "Two new sesquiterpenes from Artemisia annua L." Journal of Natural Medicines 74, no. 4 (2020): 811–18. http://dx.doi.org/10.1007/s11418-020-01436-3.

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25

Paniego, N. B., and A. M. Giulietti. "Artemisia annua L.: dedifferentiated and differentiated cultures." Plant Cell, Tissue and Organ Culture 36, no. 2 (1994): 163–68. http://dx.doi.org/10.1007/bf00037715.

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Wan, X. L., Y. Niu, X. C. Zheng, et al. "Antioxidant capacities of Artemisia annua L. leaves and enzymatically treated Artemisia annua L. in vitro and in broilers." Animal Feed Science and Technology 221 (November 2016): 27–34. http://dx.doi.org/10.1016/j.anifeedsci.2016.08.017.

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Amirmohammadi, Fereshteh, Jalal Sendi, and Arash Zibaee. "Toxicity and Physiological Effect of Essential Oil of Artemisia Annua (Labiatae) on Agriolimax Agrestis L. (Stylommatophora: Limacidae)." Journal of Plant Protection Research 52, no. 2 (2012): 185–89. http://dx.doi.org/10.2478/v10045-012-0028-1.

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Toxicity and Physiological Effect of Essential Oil of Artemisia Annua (Labiatae) on Agriolimax Agrestis L. (Stylommatophora: Limacidae) Essential oil of Artemisia annua L. was investigated to find out its toxicity and physiological aspects on the slug Agriolimax agrestis, in controlled conditions (8±1°C, 75±5 RH and 14:10 LD). The slugs received different concentrations of essential oil treated radish leaves in methanol, while the control received methanol alone. LC10, LC30, LC50 and LC90 values were estimated at 4.67, 5.3, 5.81, 7.25%, respectively. The effect of the essential oil on some imp
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GUPTA, ANIL KUMAR, MADAN MOHAN GUPTA, ABHILASHA SRIVASTAVA, et al. "CIM-Sanjeevani: A high artemisinin yielding population of Artemisia (Artemisia annua)." Journal of Medicinal and Aromatic Plant Sciences 38, no. 4 (2016): 78–83. http://dx.doi.org/10.62029/jmaps.v38i4.gupta.

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Artemisia annua L. (Asteraceae), commonly known as quinghao, is a traditional medicinal herb, native to China and widely grown in Asia and Europe. The biologically active compound artemisinin isolated from the herb of the A. annua is used as an anti-malarial drug. CSIR-CIMAP has now developed genetically improved variety of Artemisia annua with artemisinin content of 1.2%. The new variety CIM-Sanjeevani has been developed using classical breeding method of poly crossing between two existing varieties i.e. Jeevan Raksha and CIM-Arogya followed by population enrichment with desirable genes. Two
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Kobylinska, Natalia, Anatolij Shakhovsky, Olena Khainakova, et al. "‘Hairy’ root extracts as source for ‘green’ synthesis of silver nanoparticles and medical applications." RSC Advances 10, no. 65 (2020): 39434–46. http://dx.doi.org/10.1039/d0ra07784d.

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Lestari, Endang G., Ragapadmi Purnamaningsih, Muhammad Syukur, and Rosa Yunita. "Keragaman Somaklonal untuk Perbaikan Tanaman Artemisia (Artemisia annua L.) melalui Kultur In Vitro." Jurnal AgroBiogen 6, no. 1 (2016): 26. http://dx.doi.org/10.21082/jbio.v6n1.2010.p26-32.

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&lt;p&gt;Somaclonal Variability for the Improvement of Plants&lt;br /&gt;Artemisia (Artemisia annua L.) by In Vitro Culture.&lt;br /&gt;Endang G. Lestari, Rosa Yunita, and Ali Husni. Artemisia&lt;br /&gt;annua L., a family member of Asteraceae, is medicinal&lt;br /&gt;plants originated from China. The plant has been widely&lt;br /&gt;used by the local people for malaria remedy. Its active substance,&lt;br /&gt;artemisine, has been proved to hamper the malaria&lt;br /&gt;bacteria incubation, Plasmodium sp. In accordance with the&lt;br /&gt;WHO recomendation, the Department of Health of Indonesi
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Ćetković, Tamara, Anja Haverić, Lejla Čaluk Klačar, Maida Hadžić Omanović, and Sanin Haverić. "In vitro assessment of genotoxic and cytotoxic effects of Artemisia annua L. tincture." Genetics & Applications 5, no. 2 (2021): 1. http://dx.doi.org/10.31383/ga.vol5iss2pp1-9.

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The genus Artemisia (fam. Asteraceae) is one of the largest and widely distributed with around 500 species, majority used as aromatic and medicinal plants. Artemisia annua L. is widely used as a dietary spice, herbal tea, as a supplement, and in a non-pharmaceutical form for treatment of malaria and fever. It is orally consumed as capsules, extracts and tinctures and topically applied as an essential oil diluted in lotions and ointments. Artemisinin is the main constituent of Artemisia annua L. extracts. Since the discovery that the artemisinin is efficient in malaria treatment, there is also
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Austin, Publishing Group. "Artemisinin-More than a Malarial Drug." Austin Journal of Biotechnology & Bioengineering 10, no. 1 (2023): 1120. https://doi.org/10.26420/austinjbiotechnolbioeng.2023.1120.

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Abstract In Asia, Artemisia annua L. tea and press juice are used to cure malaria and its associated symptoms. Artemisia annua comes under the Anthemideae tribe, which includes the roughly 500 species of Artemisia L., is primarily distributed in Asia, Europe, and North America. Due to the presence of numerous active components or secondary metabolites, artemisia typically exhibits a wide range of bioactivity. The drug&rsquo;s active component, Artemisinin (ARS), was created as an antimalarial and is used all over the world. It&rsquo;s interesting to note that the bioactivity is not just used t
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Yunita, Rossa, and Endang G. Lestari. "KOMUNIKASI PENDEK Perbanyakan Tanaman Artemisia annua secara In Vitro." Jurnal AgroBiogen 4, no. 1 (2016): 41. http://dx.doi.org/10.21082/jbio.v4n1.2008.p41-44.

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&lt;p&gt;Artemisinin, an anti-malarial medicine&lt;br /&gt;isolated from the annual wormwood Artemisia annua,&lt;br /&gt;has a marked activity against chloroquine-resistant and&lt;br /&gt;chloroquine-sensitive strains of Plasmodium falciparum.&lt;br /&gt;This compound is useful for treatment of cerebral malaria.&lt;br /&gt;An in vitro propagation system for A. annua has been developed.&lt;br /&gt;Shoots were induced by culturing seeds of A.&lt;br /&gt;annua on a MS medium containing BAP (0, 0.1, 0.3, 0.5&lt;br /&gt;mg/l). Shoots were also formed on each seedling cultured&lt;br /&gt;on the same
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Vidic, Danijela, Amira Čopra-Janićijević, Mladen Miloš, and Milka Maksimović. "Effects of Different Methods of Isolation on Volatile Composition of Artemisia annua L." International Journal of Analytical Chemistry 2018 (August 19, 2018): 1–6. http://dx.doi.org/10.1155/2018/9604183.

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In order to determine influence of extraction method on volatile oil composition of Artemisia annua L., steam distillation, hydrodistillation, organic solvent extraction, and headspace sampling have been applied. The relative abundance of volatile compounds from the odorous aerial parts of A. annua, obtained by different extraction techniques, was analyzed by GC-MS. Exactly fifty constituents were identified. The leaf and flower essential oil yield ranged from 0.9 to 2.3% (v/w). Oxygenated monoterpenes were predominant in all samples ranged from 42.6% for steam-distilled fraction of petroleum
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35

Singh, V., R. Goel, Rajkumari, and M. Ali. "NEW ALIPHATIC CONSTITUENTS FROM THE AERIAL PARTS OF ARTEMISIA ANNUA L." INDIAN DRUGS 55, no. 01 (2018): 26–32. http://dx.doi.org/10.53879/id.55.01.11228.

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Artemisia annua L. (Asteraceae) is an aromatic annual herb, up to 2 m in height, found in temperate Asia, especially China and naturalized in many countries of the world. The plant is prescribed against fever, malaria, skin diseases, jaundice, malignant ulcers and haemorrhoids. Phytochemical investigation of the aerial parts of A. annua led to the isolation of alkyl alcohols, fatty acid esters, alkyl glucoside and fatty acids characterized as n-nonadecan-2-ol (1), n-heptadecanyl n-octadec-9,12-dienoate (2), n-octacosanyl alcohol (3), n-nonacosanyl n-octadec-9,12-dienoate (4), n-cos-(Z)-10-enoi
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36

Kobylinska, N. "SIMULTANEOUS IDENTIFICATION, QUANTIFICATION, AND ANALYSIS OF MAIN COMPONENTS OF “HAIRY” ROOT EXTRACTS OF Artemisia annua AND Artemisia tilesii PLANTS." Biotechnologia Acta 14, no. 6 (2021): 60–70. http://dx.doi.org/10.15407/biotech14.06.060.

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Aim. The profiles of polyphenolic phytochemicals in extracts of “hairy” roots of Artemisia tilesii Ledeb. and Artemisia annua L. were studied. Analytical separation and quantification of main components in extracts were evaluated. Methods. “hairy” roots were grown in vitro on Murashige and Skoog medium. High-performance chromatography coupled with different types of detection (photo diode array detection (DAD) and electrospray ionization with ultra-high resolution Qq-Time-of-Flight mass spectrometry) was used to identify and quantify the main biologically active components in ethanol extracts
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PRIHANTINI, AMALIA INDAH, AGUS SUKITO, and SANRO TACHIBANA. "Production of antioxidant compounds from tissue culture of Artemisia annua." Nusantara Bioscience 10, no. 4 (2018): 251–55. http://dx.doi.org/10.13057/nusbiosci/n100409.

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Prihantini AI, Sukito A, Tachibana S. 2018. Production of antioxidant compound from tissue culture of Artemisia annua. Nusantara Bioscience 10: 251-255. Phenolic compounds have attracted much attention because of their role in some oxidative diseases. Therefore, the study aimed to investigate the production of antioxidant compound from tissue culture of A. annua. The callus were developed on solid MS medium treated with four combination of plant growth regulators: NAA 0.5 mg/L + BA 0.5 mg/L; NAA 0.5 mg/L + kinetin 0.5 mg/L; 2,4-D 0.5 mg/L + BA 0.5 mg/L; and 2,4-D 0.5 mg/L+ kinetin 0.5 mg/L. Th
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Morales, Mario R., Denys J. Charles, and James E. Simon. "SEASONAL ACCUMULATION OF ARTEMISININ IN ARTEMISIA ANNUA L." Acta Horticulturae, no. 344 (November 1993): 416–20. http://dx.doi.org/10.17660/actahortic.1993.344.48.

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Chemat-Djenni, Z., and A. Sakhri. "Purification of artemisinin excerpt from Artemisia annua L." MATEC Web of Conferences 3 (2013): 01039. http://dx.doi.org/10.1051/matecconf/20130301039.

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Erkan; ÖZGÜÇ, YALÇINKAYA. "Antikanser Aktivite Araştırmalarında Artemisia annua L. Bitkisinin Önemi." Ankara Üniversitesi Eczacılık Fakültesi Dergisi 41, no. 3 (2017): 1–8. http://dx.doi.org/10.1501/eczfak_0000000596.

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41

Hong, Minji, Minju Kim, Haejung Jang, et al. "Multivariate Analysis of Essential Oil Composition of Artemisia annua L. Collected from Different Locations in Korea." Molecules 28, no. 3 (2023): 1131. http://dx.doi.org/10.3390/molecules28031131.

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Artemisia annua L. is distributed throughout the world and it is an important medicinal plant in Korea to treat various human diseases. Recently, A. annua has also been considered to be an effective ethnobotanical drug against COVID-19. A. annua contains an appreciable amount of essential oil with different biological properties. However, the composition of essential oils in aromatic plants can be varied depending on several factors, including geographic, genetic, ecological, etc. Hence, the present study aimed to investigate the chemical diversity of essential oils of Korean A. annua collecte
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Vijender, Singh, Ali Mohammed, Malik Archana, and Sultana Shahnaz. "New aliphatic constituents from the aerial parts of Artemisia annua L." Algerian Journal of Natural Products 5, no. 2 (2017): 515–23. https://doi.org/10.5281/zenodo.1117151.

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<em>Artemisia annua</em> L. (Asteraceae) is an aromatic annual herb, up to 2 m in height, found in temperate Asia, especially China and naturalized in many countries of the world.&nbsp; The plant is prescribed against fever, malaria, skin diseases, jaundice, malignant ulcers and haemorrhoids. Phytochemical investigation of the aerial parts of <em>A. annua</em> led to the isolation of alkyl alcohols, fatty acid esters, alkyl glucoside and fatty acids characterized as <em>n-</em>nonadecan-2&beta;-ol (isononadecanol, <strong>1</strong>), <em>n-</em>docosan-9&beta;-ol (isodocosanol, <strong>&nbsp;
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Kondža, Martin, Marta Mandić, Ivona Ivančić, Sanda Vladimir-Knežević, and Ivica Brizić. "Artemisia annua L. Extracts Irreversibly Inhibit the Activity of CYP2B6 and CYP3A4 Enzymes." Biomedicines 11, no. 1 (2023): 232. http://dx.doi.org/10.3390/biomedicines11010232.

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Artemisia annua L. has long been known for its medicinal properties and isolation of ingredients whose derivatives are used for therapeutic purposes. The CYP2B6 and CYP3A4 enzymes belong to a large family of cytochrome P450 enzymes. These enzymes are involved in the metabolism of drugs and other xeonobiotics. It is known that various compounds can induce or inhibit the activity of these enzymes. The aim of this study was to investigate the nature of the inhibitory effect of Artemisia annua extract on CYP2B6 and CYP3A4 enzymes, as well as the type of inhibition, the presence of reversible or ps
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Liu, Hua, Lingxi Jiang, Furong Tan, et al. "Validation of Artemisia Genus-Specific Gene, GEL4, for Use as an Endogenous Reference Gene in Qualitative PCR Detection of Putative Transgenic Artemisia annua." Journal of AOAC INTERNATIONAL 96, no. 3 (2013): 587–92. http://dx.doi.org/10.5740/jaoacint.11-358.

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Abstract Artemisia annua L. is a popular medical plant used against malaria. Transgenic A. annua plants have been developed to increase the artemisinin content using genetic engineering. To develop a reliable PCR method of detecting transgenic A. annua, one Artemisia specific gene, GEL4, was selected and validated as suitable. Qualitative PCR methods were assayed with 16 different A. annua ecotypes and four Artemisia plants, and identical amplified products were obtained. No amplified products were observed when genomic DNA samples were extracted from 15 different plant species. An LOD of 0.05
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45

Zhao, Guo-Zhen, Jie Li, Sheng Qin, et al. "Streptomyces artemisiae sp. nov., isolated from surface-sterilized tissue of Artemisia annua L." International Journal of Systematic and Evolutionary Microbiology 60, no. 1 (2010): 27–32. http://dx.doi.org/10.1099/ijs.0.011965-0.

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The taxonomic position of an actinomycete strain YIM 63135T, which was isolated from the surface-sterilized tissue of Artemisia annua L. collected from Yunnan province, south-west China, was determined by using a polyphasic approach. Morphological and chemical characteristics of the novel strain were consistent with those of the genus Streptomyces. It developed a pinkish aerial mycelium and pinkish-brown substrate mycelium on oatmeal agar. The cell wall of the strain contained ll-diaminopimelic acid. The menaquinones comprised MK-9(H6) (62.8 %), MK-9(H8) (31.4 %) and MK-9(H4) (5.9 %). The phos
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Odundo, J. O., D. O. Oyoo, and M. P. Nawiri. "The artemisin potential of flowers from Artemisia annua L. grown in Western Kenya." Industrial Crops and Products 49 (August 2013): 233–36. http://dx.doi.org/10.1016/j.indcrop.2013.02.016.

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47

Swamikannu, Bhuminathan, Vidhya Rekha Umapathy, Prabhu M. Natarajan, et al. "Unlocking the Therapeutic Benefits of Artemisia Annua: A Comprehensive Overview of its Medicinal Properties." Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4248—S4253. https://doi.org/10.4103/jpbs.jpbs_1250_24.

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ABSTRACT Artemisia annua L., also referred to as sweet wormwood, sweet annie, sweet sagewort, and annual wormwood (Chinese: qngho), is a species of wormwood native to temperate Asia but naturalised worldwide. It is a member of the Asteraceae family. At the moment, Artemisia annua is the sources of artemisinin and semisynthetic artemisinin derivatives (including dihydroartemisinin, artesunate, artemether, and arteether) used in the development of malaria combination treatments (ACTs = Artemisinin-based combination therapy). Animal experiments have shown that similar chemicals can prevent tumor
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48

Tian, N., S. Liu, H. Ting, et al. "An improved Agrobacterium tumefaciens mediated transformation of Artemisia annua L. by using stem internodes as explants." Czech Journal of Genetics and Plant Breeding 49, No. 3 (2013): 123–29. http://dx.doi.org/10.17221/105/2012-cjgpb.

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Transformation of Artemisia annua, which produces the sesquiterpenoid endoperoxide artemisinin widely used for the treatment of malaria, has been hampered by the low efficiency of adventitious shoot and root formation on a selective medium containing additional compounds for Agrobacterium decontamination. Here we identified several factors which were all shown to be of importance for optimization of Artemisia annua transformation. Results indicated that stem internodes showed better resistance capacity to Agrobacterium decontaminator than leaves did. Agrobacterium tumefaciens with an optical d
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Ickovski, Jovana, Katarina Stepic, and Gordana Stojanovic. "Composition of essential oils and headspace constituents of Artemisia annua L. and A. scoparia Waldst. et Kit." Journal of the Serbian Chemical Society, no. 00 (2020): 61. http://dx.doi.org/10.2298/jsc200727061i.

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Headspace volatiles (HS) and hydrodistilled essential oils (EO) of fresh aerial parts of Artemisia annua L. and A. scoparia Waldst. et Kit., were analyzed by GC-MS/FID. Artemisia ketone was found to be the most abundant component among the EO volatiles (55.8 %), as well as among HS (52.1 %) of A. annua. Additionally, in both A. annua samples, EO and HS, ?-pinene (12.7 and 24.2 %, respectively) was found in high percentage. On the other hand, it has been determined that the dominant components of A. scoparia EO and HS were different; in the essential oil capillene (63.8 %) was found as the main
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Bilia, Anna Rita, Guido Flamini, Fabrizio Morgenni, Benedetta Isacchi, and Franco FrancescoVincieri. "GC MS Analysis of the Volatile Constituents of Essential Oil and Aromatic Waters of Artemisia Annua L. at Different Developmental Stages." Natural Product Communications 3, no. 12 (2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301225.

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Artemisia annua L. (Asteraceae) still represents the only source of artemisinin, considered as one of the most important drugs for the treatment of malaria and which, more recently, has been shown to be effective against numerous types of tumors. The foliage and inflorescence of A. annua also yield an essential oil upon hydrodistillation. This oil has been evaluated at different development stages (pre-flowering and flowering) by GC/MS. The volatile oil from plants at full blooming showed numerous constituents, with germacrene D (21.2%), camphor (17.6%), β-farnesene (10.2%), β-caryophyllene (9
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