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Dissertations / Theses on the topic 'Arthritis of the knee joint'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

McAlindon, Timothy Edward. "Knee joint failure." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386627.

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2

Cruwys, Simon Charles. "Neurogenic influences on arthritis." Thesis, Queen Mary, University of London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243318.

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3

Hurley, Michael V. "Muscle function, inhibition and rehabilitation following traumatic and degenerative joint damage." Thesis, King's College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321690.

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4

Grimsholm, Ola. "Neuropeptides and neurotrophins in arthritis : studies on the human and mouse knee joint." Doctoral thesis, Umeå universitet, Integrativ medicinsk biologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1863.

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Neuropeptides, such as substance P (SP) and bombesin/gastrin-releasing peptide (BN/GRP), and neurotrophins are involved in neuro-immunomodulatory processes and have marked trophic, growth-promoting and inflammation-modulating properties. The impact of these modulators in rheumatoid arthritis (RA) is, however, unclear. An involvement of the innervation, including the peptidergic innervation, is frequently proposed as an important factor for arthritic disease. Many patients with RA, but not all, benefit from treatment with anti-TNF medications. The studies presented here aimed to investigate the

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5

Hamilton, Thomas. "Assessment of the arthritic knee." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:6a36e359-defb-4ff3-a6b5-6f459c4c40f2.

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The aim of this thesis was to establish the long-term outcomes of the Oxford medial Unicompartmental Knee Arthroplasty (OUKA), define patient selection criteria and to develop and externally validate an evidence based method of patient selection for this procedure. In the hands of the developer surgeons, outcomes following medial OUKA were found to be good with an implant survival of 94% (95%CI 92 to 96) at ten-years and 91% (95%CI 83 to 98) at fifteen-years. Across the published literature, however, variation in outcomes was observed with a meta-analysis of published series of OUKA finding es

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6

Kodys, Martin. "Návrh metodiky tvorby 3D modelu femorální části kolenní náhrady." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229892.

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The aim of the Diploma Thesis is to propose the methodology of a 3D model creation of a femoral part of a knee joint replacement. As the knee joint is the most loaded joint of the human body, the function, description and biomechanics relation is described in first part of the Thesis. The second part is focused on degenerative damage of knee joints that leads to the implantation of standard knee joint replacements. The third part deals with the construction of standard knee joint replacements and their surgery implantation. The last part of the Thesis describes the creation of an individual kn

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7

Kern, Andrew M. "Large population evaluation of contact stress exposure in articular joints for prediction of osteoarthritis onset and progression." Thesis, University of Iowa, 2011. https://ir.uiowa.edu/etd/2725.

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Contact stress exposure is thought to play a significant role in many aspects of joint degradation and pathology. Effective and accurate contact stress computation in native or pathological subject specific joints is an important tool in determining the role of contact stress in OA onset and worsening as well as eventually developing and monitoring interventions to prevent joint degradation. In the past FEA modeling has allowed for studies to be completed which relate contact stress exposure human ankle joint to the presence of radiographic OA. While promising, contact FEA for subject specific

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8

Осадчий, А. Ю. "Фізична реабілітація при артриті колінного суглобу". Thesis, Сумський державний університет, 2018. http://essuir.sumdu.edu.ua/handle/123456789/66768.

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9

Jones, Luke D. "Early knee arthritis : symptoms and structure." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:fafe8d46-9ad5-4d1e-b8f5-b2ea3757b3fb.

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Knee osteoarthritis (OA) is the commonest form of lower limb OA with a lifetime risk of over 40%. It is a disease characterised by symptoms such as pain and loss of function. In addition there are typical structural features on both radiographs and MRI. Knee OA represents a spectrum of disease, ranging from early preclinical cartilage change to established full thickness disease. Anteromedial knee OA is a particular phenotype of knee OA where disease is confined to the medial compartment. Whilst end stage arthritis is treated reliably with joint arthroplasty, those with early stage disease are

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10

Lane, Judith. "Knee joint stiffness and function following total knee arthroplasty." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4790.

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Introduction: Studies show that Total Knee Arthroplasty (TKA) is successful for the majority of patients however some continue to experience some functional limitations and anecdotal evidence indicates that stiffness is a common complaint. Some studies have suggested an association between stiffness and functional limitations however there has been no previous work which has attempted to objectively quantify knee joint stiffness following TKA. The purpose of this study was to pilot and evaluate a method for the quantitative evaluation in joint stiffness in replaced knees, OA knees and healthy

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11

Appelgren, Anna. "Neuropeptides in temporomandibular joint arthritis /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3893-8/.

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12

Crenshaw, Jeremy. "Knee-joint loading variability during gait in subjects with knee osteoarthritis." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 42 p, 2007. http://proquest.umi.com/pqdweb?did=1338917851&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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13

Van, den Heever David Jacobus. "Development of patient-specific knee joint prostheses for unicompartmental knee replacement (UKR)." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/17942.

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Thesis (PhD)--Stellenbosch University, 2011.<br>ENGLISH ABSTRACT: The knee is the largest, most complicated and incongruent joint in the human body. It sustains very high forces and is susceptible to injury and disease. Osteoarthritis is a common disease prevalent among the elderly and causes softening or degradation of the cartilage and subcondral bone in the joint, which leads to a loss of function and pain. This problem can be alleviated through a surgical intervention commonly termed a “knee replacement”. The aim of a knee replacement procedure is to relieve pain and restore normal f

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14

Li, Jialong. "Optimisation Of Ligament Balancing And Knee Joint Kinematics In Total Knee Arthroplasty." Thesis, The University of Sydney, 2023. https://hdl.handle.net/2123/29945.

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Total knee arthroplasty (TKA) is a successful surgery for the clinical management of OA. The procedure has been demonstrated to alleviate pain due to degeneration of articulating surface of the joint, restore function and mobility and increase the quality of life for recipients. Well-balanced post-operative knee joints are often based on subjective ‘feel’ of experienced surgeons rather than quantifiable references. Most alignment strategies are still referencing the bone despite the complexity in anatomical variations and presence of deformity. This dissertation aims to investigate the contrib

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15

Abdelgaied, Abdellatif Abdelfadeel Younes. "Computational wear modelling of knee joint replacements." Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582519.

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Due to the fact that a growing number of young patients require joint replacements, the expected lifetime of the prostheses is considerably increasing, and patient activities are becoming more demanding. New materials and designs are being introduced. The technical challenge lies in developing new designs, with high-performance materials, and low wear to improve prosthesis life. The main issue is to pre-clinically investigate the new materials and designs. Many researchers have reported wear in total knee replacements investigated in simulators. A single simulator test can be very expensive an

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16

Palmer, Gwen. "Modelling neuronal activity at the knee joint." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/363112/.

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The knee is a complex joint, prone to instability and damage, meaning a complicated architecture of soft tissues is necessary to ensure any stability of the joint. These structures are innervated, and play an important role in both proprioception, the sensing of a body’s own limb positions, and nociception, the sensing of painful stimuli. The purpose of this project has been to develop a computational model that can replicate the behaviour of the mechanical sensing nerve endings in the knee joint. An adapted Hodgkin-Huxley model has been developed and used to simulate the behaviour of the nerv

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17

Maniar, Nirav. "Muscle force contributions to knee joint loading." Thesis, Australian Catholic University, 2017. https://acuresearchbank.acu.edu.au/download/9092bf05e33ece328cba05aae3620898d48c8720b4140530a2b8df8e1bb03e24/6002615/MANIAR_2017_Muscle_force_contributions_to_knee_joint.pdf.

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Anterior cruciate ligament (ACL) injuries are one of the most common knee injuries suffered by athletic populations. ACL injuries are particularly burdensome due to potential surgical requirements, extensive rehabilitation time and associated financial costs for the individual and the community. Additionally, ACL injuries are associated with increased risk of early onset knee osteoarthritis. As such, ACL injury preventative and rehabilitative strategies are of paramount importance. ACL injuries typically occur during non-contact dynamic tasks, such as unanticipated sidestep cutting. At the t

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18

Relph, Nicola. "The measurement of knee joint position sense." Thesis, University of Salford, 2015. http://usir.salford.ac.uk/36795/.

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It is commonly stated proprioception or the perception of one’s own limb position, movement and effort is reduced following an anterior cruciate ligament (ACL) injury. Therefore, this thesis begins with an analysis of all current literature on this topic in the form of a meta-analysis. It became clear that the methods used to measure knee proprioception were very inconsistent and did not appear to provide normative levels of knee proprioception making it very difficult to syntheses results. This led to the thesis main objectives. The first study provided a reliable and valid method of knee joi

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19

Law, Rebecca-Jane. "Exercise and joint health in rheumatoid arthritis." Thesis, Bangor University, 2012. https://research.bangor.ac.uk/portal/en/theses/exercise-and-joint-health-in-rheumatoid-arthritis(a3a9d112-91ce-41bb-a2ec-0029ae1e48fc).html.

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The benefits of exercise for people with rheumatoid arthritis (RA) are now well-established. However, RA patients are less active than the general population. This may result from previous negative views surrounding the effects of exercise on joint health and limitations in current empirical evidence. Thesis Summary The aims of this thesis were to explore patient perceptions relating to exercise and joint health, alongside determining the physiological effects of acute exercise and exercise training on novel markers of joint health. Firstly, focus group methodology was used to collect qualitat

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20

Theoret, Daniel. "Three dimensional knee joint kinematics and lower limb muscle activity of anterior cruciate ligament deficient knee joint participants wearing a functional knee brace during running." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/27057.

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Background. Knee braces have been found to provide limited stability to the ACL deficient knee in situations where the knee is loaded during sporting movements. Different adaptation strategies have been found between patients that can cope with the injury and patients that cannot. One of the expected changes can be muscle activation characteristics of the injured knee during strenuous activity with and without a functional knee brace. Methods. Three dimensional (3D) kinematic and electromyography (EMG) data were collected from each participant for ten consecutive gait cycles during running on

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21

Miki, Nancy Patricia Hana. "Interaction of viruses with human joint material." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29591.

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An in vitro cell and organ culture system for the study of human arthrotropic viruses was established to determine the permissiveness of joint cells and tissue to five strains of rubella virus (RV), adenovirus type 2 (Ad) and human parvovirus (B19). A semi-continuous line of fetal chondrocytes (FC) and primary synovial membrane/cartilage (SMC) cells were used to investigate virus/joint cell interactions. In addition, the SMC cells were used to determine the ability of a virus to establish a persistent infection in cells of joint origin. Intact joint tissue containing both synovial membrane a

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22

Hutter, Erin E. "The Effect of Surgical Technique During Total Knee Arthroplasty on Knee Joint Stability." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1384641986.

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23

Petersson, Ingemar F. "Developing knee joint osteoarthritis clinical, radiographical and biochemical features /." Lund : Dept. of Rheumatology, Lund University Hospital, 1997. http://catalog.hathitrust.org/api/volumes/oclc/39783203.html.

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24

Ma, Helen. "Quality of life changes after knee-joint replacement." Click to view the E-thesis via HKUTO, 2002. http://sunzi.lib.hku.hk/hkuto/record/B31971192.

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25

Chen, Elvis Chai-Shin. "Three-dimensional joint kinematics of total knee replacements." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0004/MQ42595.pdf.

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26

馬海倫 and Helen Ma. "Quality of life changes after knee-joint replacement." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B31971192.

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27

Mazzucco, Daniel Clarke 1976. "Rheology of joint fluid in total knee arthroplasty." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/89322.

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28

Reisse, Franziska. "Effect of malalignment on knee joint contact mechanics." Thesis, Anglia Ruskin University, 2014. http://arro.anglia.ac.uk/550363/.

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Osteoarthritis (OA) is a debilitating joint disease that leads to significant pain, loss of mobility and quality of life. Knee malalignment results in increased joint pressure, which is a primary cause for OA progression. High Tibial Osteotomy (HTO) is a surgical procedure to correct malalignment and redistribute load in the knee joint, reduce peak pressure and delay OA progression. However, clinical outcomes have been unpredictable. Therefore, the aim of this study was to determine the relationship between malalignment and knee contact mechanics. A 3D computational model was created from magn

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29

Reisse, Franziska. "Effect of malalignment on knee joint contact mechanics." Thesis, Anglia Ruskin University, 2014. https://arro.anglia.ac.uk/id/eprint/550363/1/FReisseThesis_final.pdf.

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Osteoarthritis (OA) is a debilitating joint disease that leads to significant pain, loss of mobility and quality of life. Knee malalignment results in increased joint pressure, which is a primary cause for OA progression. High Tibial Osteotomy (HTO) is a surgical procedure to correct malalignment and redistribute load in the knee joint, reduce peak pressure and delay OA progression. However, clinical outcomes have been unpredictable. Therefore, the aim of this study was to determine the relationship between malalignment and knee contact mechanics. A 3D computational model was created from mag

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30

Murray, Amanda Megan. "The Effects of High-Velocity Power Training on Knee Joint Mechanics in Knee Osteoarthritis." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1404391903.

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31

Gardinier, Joseph D. "Evaluation of an EMG-driven model and its ability to estimate joint moments at the knee." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 80 p, 2007. http://proquest.umi.com/pqdweb?did=1251904611&sid=2&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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32

Egan, Colin Gerard. "Neurovascular and inflammatory mechanisms in the joint." Thesis, University of the West of Scotland, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247620.

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33

Runciman, R. John. "Biomechanical model of the shoulder joint." Thesis, University of Strathclyde, 1993. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21385.

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A biomechanical model of the glenohumeral joint has been developed to investigate muscle and joint loading during real life three-dimensional activities. Based on a rigid body mechanics approach, the model incorporates algorithms to correct for curved muscle paths and bone geometry, providing realistic muscle orientation over a wide range of limb positions. An optimization routine has been incorporated, minimizing overall maximum muscle stress in the 26 individual muscle elements considered. The model utilizes anatomical muscle and bone data, subject anthropometric data, kinematics measured us

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34

Högberg, Erland. "Synovial metabolism after knee joint arthroscopy : a microdialysis study /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-652-2/.

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35

Tsaopoulos, Dimitrios E. "In vivo knee joint mechanics : implications for musculotendon modelling." Thesis, Manchester Metropolitan University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485989.

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The general aim of this thesis was to study knee joint mechanics in-vivo in healthy participants with particular attention to the quantification of the patellar tendon moment arm length and the accurate calculation of the actual knee joint moment when dynamometry-based musculotendon loading calculations are perfonned. Following a review of the relevant literature, the next chapter examined the pote!lttal relation between patellar tendon moment ann length and several relevant anthropometric characteristics. In the third chapter the variation in the patellar tendon moment ann length due to the u

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36

Kader, Ibrahim Babul Salam. "Modelling and control of paraplegic's knee joint (FES-swinging)." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556679.

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The use of electrical signals to restore the function of paralyzed muscles is called functional electrical stimulation (PES). PES is a promising method to restore mobility to individuals paralyzed due to spinal cord injury (SCI). This thesis is concerned with the development of an accurate paraplegic knee joint model and control of electrically stimulated muscle. The modelling of musculoskeletal of paraplegic's lower limb is significantly challenging due to the complexity of the system. The first aim of this study is to develop a knee joint model capable of relating electrical parameters to dy

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37

Feikes, Jennifer Dorothy. "The mobility and stability of the human knee joint." Thesis, University of Oxford, 2000. http://ora.ox.ac.uk/objects/uuid:25df7636-8b88-4c8a-8e54-57b3a9cac525.

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Separating the study of kinematic geometry of the human knee from the study of its behaviour under load provides insight into the complex relationship between form and function at the joint. The development of a three-dimensional mathematical model which examines the mobility and stability of the joint in sequence is described in this thesis. A previously proposed model of knee mobility, in which the ligaments and ar- ticular surfaces act as rigid constraints between the bones in a single degree-of- freedom spatial mechanism, was re-examined and its limitations addressed. A new geometric-numer

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38

Foley, Elizabeth Louise. "Tibial rotation in patients after total knee joint replacement." Thesis, University of Strathclyde, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248949.

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39

Van, Der Merwe Johan. "Continued development of a joint-type knee wear simulator." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/19953.

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Thesis (MScEng)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: This thesis is concerned with the continued development of the Stellenbosch University joint-type knee wear simulator. Initially, information regarding simulators from the literature and commercial entities was collected to provide a knowledge base for current and future work. To further the design of the simulator itself, electronic hardware and software subsystems was developed and evaluated during experimental testing procedures. National Instruments’ cDAQ 9174 data acquisition unit was deemed inadequate for real-tim

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40

Bei, Yanhong. "Dynamic simulation of knee joint contact during human movement." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0002364.

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41

Hammond, Alison. "Evaluating joint protection education for people with rheumatoid arthritis." Thesis, University of Nottingham, 1994. http://eprints.nottingham.ac.uk/28957/.

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Joint Protection (JP) education is considered an essential component of therapeutic programmes for Rheumatoid Arthritis (RA) patients. The main emphasis is teaching alternate patterns of movement at affected joints to reduce joint stress, particularly in the hands and wrists (Hand JP). Little has been published investigating patients' knowledge of, attitudes towards and adherence to Hand JP following education. Assessments were developed to evaluate these constructs. Reliability and validity were established. A pretest-posttest trial was conducted with RA patients attending a 4 x 2 hour arthri

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42

Dularay, B. "Mechanisms of inflammation and joint damage in rheumatoid arthritis." Thesis, University of Bristol, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233633.

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43

Dang, Lei. "Osteoblastic PLEKHO1 contributes to joint inflammation in rheumatoid arthritis." HKBU Institutional Repository, 2019. https://repository.hkbu.edu.hk/etd_oa/687.

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Background: Osteoblasts participating in the inflammation regulation gradually obtain concerns. However, its role in joint inflammation of rheumatoid arthritis (RA) is largely unknown. Here, we investigated the role of osteoblastic pleckstrin homology domain-containing family O member 1 (PLEKHO1), a negative regulator of osteogenic lineage activity, in regulating joint inflammation in RA. Methods: The level of osteoblastic PLEKHO1 in RA patients and collagen-induced arthritis (CIA) mice was examined. The role of osteoblastic PLEKHO1 in joint inflammation was evaluated by a CIA mice model which

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44

Cheung, Peter Pak Moon. "The Reliability Of Joint Count Assessment In Rheumatoid Arthritis." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10274.

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Background: Optimal management of rheumatoid arthritis relies on treating to target and tight control of disease activity through accurate and regular identification of synovitis as part of disease activity monitoring. Joint counts (tender and swollen joints) have traditionally been used for assessment of disease activity. However, the reliability of joint counts, particularly, the swollen joint count has been questionable. Objectives: To evaluate the reliability of joint counts, particularly the swollen joint count, derived by physicians, nurses as well as patients, and investigate ways to

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45

Woodburn, James. "Kinematics at the ankle joint complex in rheumatoid arthritis." Thesis, University of Leeds, 2000. http://etheses.whiterose.ac.uk/753/.

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This thesis investigates the three-dimensional kinematics at the ankle joint complex in rheumatoid arthritis. Previous studies have identified the rearfoot as a common site for inflammatory activity in rheumatoid arthritis resulting in painful and disabling deformity for which there are no proven interventions. A generic electromagnetic tracking system was developed to undertake three-dimensional kinematics at the ankle joint complex in the bare and shod foot during gait. A joint simulator was designed, manufactured and commissioned in house to test the accuracy of the system. The results indi

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46

Szklar, O. (Oleh). "Development of an unconstrained two-force dynamic simulator for the human knee joint." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63376.

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47

Monk, Andrew Paul. "The patellofemoral joint : form and function." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:96ce09f2-a72c-46ed-94fd-ed10213959fd.

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The patellofemoral joint (PFJ) is a common source of problems in Orthopaedics and is the source of poorly defined pain and poor function in both normal and replaced knees. Before problems of the PFJ can be fully comprehended a better understanding of the basic form and function of the PFJ is required. The aim of this thesis therefore is to investigate the shape and kinematics of the PFJ and their inter-relations in both normal and replaced knees. The first part of this thesis was concerned with the shape (or form) of the PFJ. Species from the human ancestry over the previous 400 million years

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48

Wilson, David Robert. "Three-dimensional kinematics of the knee." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320163.

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49

Sambatakakis, A. "Biomechanics of imbalance in the reconstruction of the arthritic knee." Thesis, University of Strathclyde, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312145.

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50

Rahman, Md Mahbubur. "Identification and functional importance of kallikreins in inflammatory joint disease." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385694.

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