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1

Ciancio, A., and K. G. Mukerji. Integrated management of arthropod pests and insect borne diseases. Dordrecht: Springer, 2010.

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2

Marcondes, Carlos Brisola, ed. Arthropod Borne Diseases. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-13884-8.

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3

Ciancio, Aurelio, and K. G. Mukerji, eds. Integrated Management of Arthropod Pests and Insect Borne Diseases. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-8606-8.

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4

World Health Organization. Division of Vector Biology and Control. Geographical distribution of arthropod-borne diseases and their principal vectors. [Geneva, Switzerland]: World Health Organization, Vector Biology and Control Division, 1989.

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5

Society for General Microbiology. Symposium. Microbe-vector interactions in vector-borne diseases. Cambridge [Eng.]: Cambridge University Press, 2004.

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6

Marcondes, Carlos Brisola. Arthropod Borne Disease. Springer International Publishing AG, 2016.

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7

Mavingui, Patrick, Claire Valiente Mor, and Pablo Tortosa. Exploiting symbiotic interactions for vector/disease control. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789833.003.0011.

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Arthropods transmit a variety of diseases to humans and animals, including arboviruses, bacteria and parasites. No efficient treatments or control methods are available for many vector-borne diseases, especially for emerging diseases. Therefore, the development of alternative strategies aiming at controlling disease transmission is encouraged worldwide. Although transmission phenomenon is a result of complex interactions involving several actors evolving in a changing environment, the biotic relationship between pathogens and their vectors represents a key step in successful disease transmission. Recent studies highlighted a strong impact of microbiomes on the life-history traits of arthropod hosts. This chapter emphasizes those biotic interactions having an impact on adaptive traits influencing disease transmission. Evidence in behavioral alterations of vector populations/individuals with relevance to vector-pathogen transmission mitigation is reviewed. Opportunities to take advantage of such biotic processes in the control of vector-borne diseases in different epidemiological, entomological and environmental settings are explored.
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8

Marcondes, Carlos Brisola. Arthropod Borne Diseases. Springer, 2018.

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9

Marcondes, Carlos Brisola. Arthropod Borne Diseases. Springer London, Limited, 2016.

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10

Integrated Management Strategy for Arboviral Disease Prevention and Control in the Americas. Organización Panamericana de la Salud, 2020. http://dx.doi.org/10.37774/9789275120491.

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In recent years, conditions in the Region of the Americas have been highly favorable for the introduction and spread of arthropod-borne viral infections (arboviral diseases). Although dengue has been circulating for over 400 years, the number of cases reported since the year 2000 represents an unprecedented increase, with four serotypes in circulation. Since that year, 19.6 million cases of dengue have been reported to PAHO/WHO, including more than 800,000 severe cases and over 10,000 deaths. In 2015 and 2016 alone, more than 4.8 million cases were reported, 17,000 of them severe, resulting in 2,000 deaths. Despite a 23% reduction in the dengue case-fatality rate in the last six years (from 0.069% to 0.053%), the continued risk of severe disease and even death poses a serious public health problem in the Americas. Today, arboviruses present an extremely complex and unstable epidemiological situation, given the simultaneous epidemic circulation of three arboviral diseases and the risk that others could become epidemics, for example, Mayaro fever. Countries are aware that this complex situation can only be addressed with a comprehensive and multidisciplinary approach. The development of IMS-arbovirus is part of a history of technical cooperation between PAHO/WHO and the countries and territories of the Americas. It is based on the lessons learned during the development and implementation of national IMS-dengue programs in recent years. This history of cooperation is not new. It dates back to October 1947, with the adoption of Resolution CD1.R1 during the first Directing Council of PAHO. This resolution stated that the solution to the problem of urban yellow fever would be the eradication of Ae. aegypti in the entire hemisphere. The success of that campaign was demonstrated in 1962, with the eradication of this vector in 18 countries in the Region and several Caribbean islands.
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11

Day, Michael J. Arthropod-Borne Infectious Diseases of the Dog and Cat. Taylor & Francis Group, 2020.

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12

Mukerji, K. G., and Aurelio Ciancio. Integrated Management of Arthropod Pests and Insect Borne Diseases. Springer Netherlands, 2012.

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13

Day, Michael J. Arthropod-Borne Infectious Diseases of the Dog and Cat. Taylor & Francis Group, 2016.

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14

Arthropod-borne Infectious Diseases of the Dog And Cat. Lippincott Williams & Wilkins, 2005.

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15

Day, Michael J., ed. Arthropod-borne Infectious Diseases of the Dog and Cat. CRC Press, 2016. http://dx.doi.org/10.1201/b19686.

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16

Day, Michael J. Arthropod-Borne Infectious Diseases of the Dog and Cat. Taylor & Francis Group, 2016.

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17

Shaw, Susan E., and Michael J. Day. Arthropod-borne Infectious Diseases of the Dog and Cat. Taylor & Francis Group, 2005.

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18

Arthropod-Borne Infectious Diseases of the Dog and Cat. Manson Publishing, Limited, 2005.

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19

Organization, World Health, ed. Arthropod-borne and rodent-borne viral diseases: Report of a WHO Scientific Group. Geneva: World Health Organization, 1985.

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20

World Health Organization. Division of Vector Biology and Control., ed. Geographical distribution of arthropod-borne diseases and their principal vectors. [Geneva]: World Health Organization, Vector Biologyand Control Division, 1989.

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21

Day, Michael J. Arthropod-Borne Infectious Diseases of the Dog and Cat 2nd Edition. Taylor & Francis Group, 2016.

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22

Brown, Charles R., and Valerie A. O'Brien. Are Wild Birds Important in the Transport of Arthropod-Borne Viruses? University of California Press, 2012.

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23

Drotman, D. Peter. Arthropod-borne Infections: A Reprint From The Journal, ôemerging Infectious Diseasesö. Diane Pub Co, 2004.

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24

Sun, Lisa, and Michael V. Johnston. Rickettsial Diseases. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0157.

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Tick-borne rickettsioses are emerging as more important health problems throughout the world. The spotted fever group including Rickettsia rickettsia can cause encephalopathy, meningitis and brain damage by selectively targeting capillary endothelial cells in the brain, and stimulating inflammation, capillary leakage, hemorrhage, and intravascular coagulation. Rickettsia are are arthropod-borne gram-negative coccobacilli bacteria and are obligate intracellular organisms that do not survive in artificial medium. In North and South America, the most common rickettsial disorder is rocky mountain spotted fever (RMSF) transmitted by the dog tick Dermacentor variabilis or the wood tick Dermacentor andersoni. A characteristic “starry sky” pattern can be seen on MRI imaging of the brain in some patients with RMSF encephalopathy and is thought to reflect the organisms targeting of brain endothelial cells in capillaries the white matter. Early treatment with doxycycline is curative and reverses signs of encephalopathy if given within a few day of onset, but delayed treatment can be associated with permanent neurological disability. The typhus group of rickettsia bacteria include R. prowazekii, which causes epidemic typhus and R. typhi, which causes murine typhus (endemic) typhus in tropical and subtropical parts of the world. Flying squirrels and humans carry R prowazekii and rats are carry R. typhi. Q fever caused by the rickettsia organism Coxiella burnetti is transmitted from farm animals including sheep and is seen throughout the world including the United States.
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25

Force, Wyoming Bio-Security Laboratory Task. Bio-Security Laboratory Task Force final report. [Cheyenne?, Wyo.] Bio-Security Laboratory Task Force, 2006.

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