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Dissertations / Theses on the topic 'Articular cartilage'

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1

Getgood, Alan Martin John. "Articular cartilage tissue engineering." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608764.

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2

Gratz, Kenneth R. "Biomechanics of articular cartilage defects." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3284116.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed January 9, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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3

Arkill, Kenton Paul. "Mass transport in articular cartilage." Thesis, University of Exeter, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421565.

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4

Burgin, Leanne Victoria. "Impact loading of articular cartilage." Thesis, University of Aberdeen, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288339.

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Impact loads have been implicated in the initiation of secondary osteoarthritis but in the absence of defined injury this is difficult to rest rigorously.  The response to controlled impacts of samples of cartilage and bone in isolation and together, may yield valuable insights into how tissue properties may influence degenerative changes associated with osteoarthritis. A rigid instrumented drop tower was constructed and interfaced to a LabVIEW software oscilloscope modified to capture and store data to disk.  Controlled impact loads were applied to cores of articular cartilage, both isolated
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5

Rowles, Christopher. "Visualisation of Articular Cartilage Microstructure." Thesis, Curtin University, 2016. http://hdl.handle.net/20.500.11937/52984.

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This thesis developed image processing techniques enabling the detection and segregation of biological three dimensional images into its component features based upon shape and relative size of the features detected. The work used articular cartilage images and separated fibrous components from the cells and background noise. Measurement of individual components and their recombination into a composite image are possible. Developed software was used to analyse the development of hyaline cartilage in developing sheep embryos.
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6

Girdler, N. M. "The role of mandibular condylar cartilage in articular cartilage repair." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309110.

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7

Chan, Alex Dart Ming. "Neurogenic modulation of articular cartilage degeneration." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ41123.pdf.

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8

Covert, Rebeccah Jean. "Durability evaluation of articular cartilage prostheses." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/17596.

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9

Goldsmith, Andrew Alan John. "Biphasic modelling of synthetic articular cartilage." Thesis, University of Bath, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321846.

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10

Ardill, Jennifer Maureen. "Optical measurement of articular cartilage roughness." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241325.

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11

Barton, Nicholas J. "Accurate assessment of articular cartilage roughness." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334495.

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12

Kerin, Alexander James. "The mechanical failure of articular cartilage." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265315.

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13

Eldridge, Suzanne. "Agrin contributes to articular cartilage homeostasis." Thesis, Queen Mary, University of London, 2016. http://qmro.qmul.ac.uk/xmlui/handle/123456789/12812.

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Osteoarthritis is a leading cause of disability for which there is no cure. We have discovered that the multidomain signalling protein Agrin, most commonly known for its requirement at the neuromuscular junction, strongly promotes chondrocyte differentiation and cartilage formation in vivo. Agrin is expressed in normal cartilage but absent in osteoarthritis. In vitro, Agrin knockdown resulted in the downregulation of the cartilage transcription factor SOX9 and other cartilage-specific extracellular matrix molecules. Conversely, the addition of exogenous Agrin supported cartilage differentiatio
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14

Lin, John W. (John Wei-Chieh). "Electrokinetic evaluation of human articular cartilage." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/36644.

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15

Stinn, Jennifer L. (Jennifer Leigh). "Inhibition of metalloproteinases in articular cartilage." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/38745.

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Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1995.<br>Includes bibliographical references (leaves 70-74).<br>by Jennifer L. Stinn.<br>M.S.
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16

Stadnik, Paulina. "Mechanically-regulated microRNAs in articular cartilage." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/97563/.

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Introduction: The role of microRNAs (miRs) in articular cartilage is still not well established, however many studies have reported the differential expression of a number of miRs between healthy and osteoarthritic (OA) articular cartilage. These studies have focused on the OA pathology itself without considering the impact of mechanical load, which is one of the major risk factors implicated in the loss of cartilage integrity and the onset of OA development. Previous studies have already identified a number of mechanically-regulated miRs, therefore I hypothesised that (i) physiological and no
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17

Bliss, Cody Larry. "Sensate Scaffolds for Articular Cartilage Repair." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194815.

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Polymer scaffold use has become commonplace in tissue engineering strategies. Scaffolds provide sturdy interfaces that securely anchor tissue engineered constructs to their designated locations. Researchers have used scaffolds to provide support to developing tissues as well as a growth template to aid the development of the desired phenotypic structure. In addition to using scaffolds for their mechanical support, scaffolds can be used as a diagnostic tool by attaching sensors. Strain gauge sensors have been attached to scaffolds to monitor compression and elongation. These polybutylterpha
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18

Andrade, Andre Luis Lugnani de. "Expressão do fator de transcrição HIF - 1'alfa' em condrocitos humanos cultivados em condições normais de oxigenio." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309649.

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Orientador: Ibsen Bellini Coimbra<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-07T22:55:15Z (GMT). No. of bitstreams: 1 Andrade_AndreLuisLugnanide_M.pdf: 2450375 bytes, checksum: f33edb219ba25e56f663f1256a99bbeb (MD5) Previous issue date: 2006<br>Resumo: Introdução: Os condrócitos da cartilagem articular vivem em um ambiente com baixa concentração de oxigênio. Nestas condições, a proteína do fator induzido por hipóxia (HIF-1a) mantém-se estável e ativa genes que são fundamentais na homeostase do oxigênio.
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19

Lorenzo, Pilar. "Identification and characterization of a novel cartilage gene product CLIP, which is an early indicator of osteoarthritis." Lund : Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/57426102.html.

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20

Stoker, Aaron. "Evaluation of the metabolic responses of normal and osteoarthritic cartilage in vitro and in vivo /." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3144460.

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21

Coelho, Lívia de Paula. "Células-tronco mesenquimais autólogas no tratamento da osteoartrite induzida da articulação coxofemoral em coelhos (Oryctolagus cuniculus) /." Jaboticabal, 2017. http://hdl.handle.net/11449/150483.

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Orientador: Bruno Watanabe Minto<br>Banca: Luis Gustavo Gosuen Gonçalves Dias<br>Banca: Paulo César Jark<br>Resumo: A cartilagem articular possui capacidade de reparação limitada, aumentado a predisposição ao desenvolvimento de alterações degenerativas, muitas vezes irreversíveis. Diversas formas de tratamento, cirúrgicas ou conservativas, são descritas, entretanto a terapêutica da osteoartrite continua sendo grande desafio ao médico veterinário. Neste contexto, a pesquisa envolvendo células-tronco mesenquimais destaca-se na busca de melhorias e avanços na reparação da cartilagem articular. Ob
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22

Jeffrey, Janet Elizabeth. "The response of articular cartilage to impact loading." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25206.

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23

Bishop, Joanna Charlotte. "Biology of the articular cartilage progenitor cells." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55374/.

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24

Campbell, E. M. "Measurement of articular joint cartilage by MRI." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597258.

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Magnetic Resonance Imaging (MRI) is increasingly used to assess damage and disease in articular joints. This Thesis describes improvements in hardware and pulse sequences, to facilitate the visualization and quantitation of articular cartilage in human and rabbit knees, and in interphalangeal (IP) finger joints. Work on the human knee focused on the acquisition of localised 3D data-sets from each compartment individually, using a surface coil in transmit/receive mode. The advantage of the increase spatial resolution from localised MRI, was illustrated by comparison of the resulting patella art
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25

Reissis, Nikolaos. "A novel method of articular cartilage repair." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1445027/.

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Articular cartilage repair of post-traumatic articular cartilage defects and well-defined articular cartilage pathology is challenging in clinical practice and has been the focus of investigations for many years. In the present thesis a newly developed polymer system, based on poly-ethyl-methacrylate PEMA polymer and tetra-hydro-furfuryl methacrylate THFMA monomer has been exploited for the repair of large, full-thickness articular cartilage defects, created in a weight-bearing surface in the rabbit knee joint. The method of implantation is simple and easily reproducible and can be performed i
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26

Sasazaki, Yoshihiro. "Ultrastructure of articular cartilage under tensile strain." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410724.

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27

Inamdar, Sheetal Rajendra. "Nanoscale mechanics of collagen in articular cartilage." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/36223.

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Articular cartilage is a mechanically important soft tissue whose organisation at the micro- and nanoscale is critical for healthy joint function and where degeneration is associated with widespread disorders such as osteoarthritis. The tissue possesses a complex, graded and depth-dependent structure and at the nanoscale, cartilage mechanical functionality is dependent on the collagen and hydrated proteoglycans that form the extracellular matrix. The structure and in situ dynamic response of the collagen fibrils at the nanoscale, however, remain unclear. Here we utilise small angle X-ray diffr
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28

Schroeder, Matthew O. "Biotribology : articular cartilage friction, wear, and lubrication /." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-12302008-063639/.

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29

Bont, Lambert G. M. de. "Temoromandibular joint articular cartilage structure and function." Groningen : Rijksuniversiteit, 1985. http://catalog.hathitrust.org/api/volumes/oclc/38175470.html.

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30

Olsen, Sigb. "Modelling of articular cartilage load-carriage biomechanics." Thesis, Queensland University of Technology, 2003.

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31

Silva, Anderson Coutinho da. "Estudo da osteoartrose em joelhos de cães secundária à ruptura do ligamento cruzado cranial." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5145/tde-09062009-165130/.

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INTRODUÇÃO e OBJETIVO: A osteoartrite (OA) embora frequente tem patogênese incerta em humanos. Descrevemos modelo experimental original de OA em cães, analisando em dois tempos diferentes as consequências da Ruptura Espontânea do Ligamento Cruzado Cranial (RLCCr). MÉTODOS: Vinte animais machos com menos de 5 anos ( 20 a 45 Kg) com RLCCr submetidos à artrotomia para estabilização articular tiveram fragmentos articulares removidos para análise. O grupo RLCCr < 20 (10 animais) foi operado antes dos vinte dias e o grupo > 20 (10 animais) após 20 dias do início da lesão. Sete animais com OA pré-exi
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32

Hoch, Johanna M. "SERUM CARTILAGE OLIGOMERIC MATRIX PROTEIN: A BIOMARKER FOR ACUTE ARTICULAR CARTILAGE DAMAGE." UKnowledge, 2012. http://uknowledge.uky.edu/rehabsci_etds/3.

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Bone bruise lesions (BBL) are documented on MRIs diagnosing acute knee ligament injury (AKLI). Recent evidence has indicated that a majority of patients that sustain an AKLI, especially anterior cruciate ligament (ACL) knee injury, will develop post-traumatic osteoarthritis (PTOA) 10-20 years following injury. It has been proposed that the initial damage sustained to the articular cartilage overlying BBL causes a cascade of events that may result in PTOA. Researchers have proposed a modification to treatment protocols for more severe BBL, or have stressed the need for the development of protec
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33

Zhang, Le. "Neutral solute transport in cartilage." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 165 p, 2008. http://proquest.umi.com/pqdweb?did=1601524361&sid=8&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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34

Lawrence, C. E. "The regeneration of articular tissues." Thesis, Anglia Ruskin University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380722.

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Changes in the structural organization of cartilage and synovial tissue, or in the macromolecules produced by their cells, alter the properties of the tissues. Elucidation of the changes under controlled experimental conditions could make a significant contribution to the understanding of the pathogenesis of arthritis. To this end a model system has been developed to study proteoglycan and collagen regeneration in porcine articular cartilage and synovial tissue: partially depleted of matrix by exogenous enzyme(s), the tissues were maintained in organ culture, the medium consisting of Dulbecco'
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35

Brodkin, Kathryn Rhea. "Chondrocyte behavior in monolayer culture : the effects of protein substrates and culture media." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/20216.

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36

Fuente, Fabien Raymond. "Electromechanical indentation properties of hydrated biomaterials." Thesis, Georgia Institute of Technology, 2001. http://hdl.handle.net/1853/17142.

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37

Farias, Neto Arcelino 1983. "Influência de alterações oclusais na articulação temporomandibular e crescimento mandibular = estudo em modelo animal." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290520.

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Orientador: Célia Marisa Rizzatti Barbosa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-18T16:04:07Z (GMT). No. of bitstreams: 1 FariasNeto_Arcelino_D.pdf: 1895628 bytes, checksum: 3d9e789620307fdbeaffe939bf75437e (MD5) Previous issue date: 2011<br>Resumo: A cartilagem articular do côndilo mandibular é responsável pelo crescimento ósseo endocondral durante o desenvolvimento mandibular. Ela depende do funcionamento adequado da articulação temporomandibular (ATM) para sua diferenciação e maturação. Trabalh
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38

Lei, Fulin. "Modeling of articular cartilage optimization, large deformation, and microstructure /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 1.21 Mb., 176 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3220728.

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39

Nugent, Gayle E. "Biomechanical regulation of articular cartilage metabolism of proteoglycan 4 and articular surface integrity." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3310007.

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Thesis (Ph. D.)--University of California, San Diego, 2006.<br>Title from first page of PDF file (viewed September 19, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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40

Smyth, Patrick A. "Viscoelastic behavior of articular cartilage in unconfined compression." Thesis, Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47656.

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Previous decades of cartilage research have predominantly focused on decoupling the solid and fluid interactions of the mechanical response. The resulting biphasic and triphasic models are widely used in the biomechanics community. However, a simple viscoelastic model is able to account for the stress-relaxation behavior of cartilage, without the added complexity of solid and fluid interactions. Using a viscoelastic model, cartilage is considered a single material with elastic and dissipative properties. A mechanical characterization is made with fewer material parameters than are required
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41

Solomon, Daniel. "Phosphate transport and mineralising processes in articular cartilage." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436955.

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42

Thomas, Carla Marie. "Chondrocyte death by apoptosis and articular cartilage degradation." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445808.

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43

Clements, Kristen Mary. "Mechanical disruption of articular cartilage cells and matrix." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340082.

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44

Marcus, Paula Louise. "Plasticity and interactions of articular cartilage progenitor cells." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/54742/.

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Articular cartilage is an avascular and aneural tissue and this is, in part, attributable to its low intrinsic capacity for repair after injury. Research is now focusing on alternate cell sources for tissue engineering of damaged cartilage, and recently a population of progenitor cells has been identified within the surface zone of bovine articular cartilage. These cells are capable of differentiating along a variety of mesenchymal lineages and are thought to be required for the appositional growth of the cartilage. The aims of this thesis were to further characterise these cells and determine
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45

Warren, James Phillip. "Self-assembling peptide hydrogels for articular cartilage repair." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/17538/.

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Osteoarthritis affects millions of people globally, with damage to articular cartilage causing pain and altered mechanics during articulation. The treatment for late stage osteoarthritis is surgical intervention ultimately leading to total joint replacements. These treatments are not ideal for younger or more active patients so there is a clinical need for an early stage intervention treatment to reduce or stop the progression of osteoarthritis. It has been reported that there is a correlation between the loss of glycosaminoglycans (GAGs) from within osteoarthritic cartilage and the changes in
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46

Wei, Wenbo. "Knee Osteoarthritis: gagCEST MR Imaging of Articular Cartilage." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1365247669.

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47

Rebenda, David. "Effect of Viscosupplementation on Friction of Articular Cartilage." Doctoral thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-449087.

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Disertační práce se zabývá experimentálním studiem viskosuplementů na bázi kyseliny hyaluronové, které se aplikují do synoviálních kloubů postižených osteoartrózou. Hlavní pozornost byla věnována objasnění vlivu koncentrace a molekulové hmotnosti kyseliny hyaluronové na tření v kontaktu kloubí chrupavky resp. změnám tření v kontaktu po smíchání osteoartritické synoviální kapaliny s exogenní kyselinou hyaluronovou. Důležitou součástí experimentů bylo rovněž studium reologických vlastností synoviální kapaliny a kyseliny hyaluronové. Výsledky ukázaly, že molekulová hmotnost kyseliny hyaluronové v
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48

Docimo, Jennifer E. "Diffusion measurements in articular cartilage under compressive loading." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 102 p, 2008. http://proquest.umi.com/pqdweb?did=1654494261&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Arora, Arvind. "Potential of qMRI in the study of articular cartilage and cartilage repair tissue." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613644.

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Whittaker, Katharina Anna. "Ion transport by isolated bovine articular chondroyctes." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316916.

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