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1

Medvedev, V. N., G. I. Kharitonov, and I. V. Bilalov. "Effect of operations in artificial circulation on luminoldependent chemoluminescence of blood." Kazan medical journal 77, no. 6 (1996): 415–18. http://dx.doi.org/10.17816/kazmj104750.

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The spontaneous hemoluminescence of blood and wound discharge in 26 patients operated in artificial circulation is studied. In uncomplicated course during artificial circulation and after operation independent of the effect of applied hemodilutants the increase of hemoluminescence of blood is found. Similar changes on days 23 after intervention are revealed in wound discharge. The indices approach to the initial values on days 45 after artificial circulation. Deviations from described dynamics coincide, as a rule, with grave postoperative state of patients. On the basis of the results of inves
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2

Lerner, Alexander Y. "Artificial Blood Circulation: Stabilization, Physiological Control, and Optimization." Artificial Organs 14, no. 2 (2008): 110–17. http://dx.doi.org/10.1111/j.1525-1594.1990.tb01604.x.

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3

Rubanenko, Olesya A., O. V. Fatenkov, S. M. Khokhlunov, and L. V. Limareva. "The dynamics of indicators of inflammation, antioxidant defense and myocardium ischemia under coronary bypass surgery using artificial blood circulation and on functioning heart." Medical Journal of the Russian Federation 22, no. 3 (2016): 116–20. http://dx.doi.org/10.18821/0869-2106-2016-22-3-116-120.

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The article considers evaluation of indicators of inflammation, antioxidant defense and myocardium ischemia in patients with ischemic heart disease exposed to coronary bypass surgery using artificial blood circulation or on functioning heart. The sampling included 96 patients distributed to two groups. The first group included 84 patients (81% of males, average age 62,2±7,7 years) exposed to coronary bypass surgery in conditions of artificial blood circulation. The second group included 12 patients (91,7% of males, average age 59,8±8,0 years) exposed to coronary bypass surgery on functioning h
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4

Leibuss, Roberts, Olga Posredņikova, Irina Pupkeviča, et al. "Transcranial Duplex Ultrasonography Measurements Towards Identification of Blood Vessel Conditions: Artificial Cerebral Blood Flow in Pathologies." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 76, no. 3 (2022): 346–51. http://dx.doi.org/10.2478/prolas-2022-0052.

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Abstract The aim of the study was to investigate how cerebral vasospasm, vasodilation and haemorrhage under artificial circulation conditions during cardiopulmonary bypass affect transcranial duplex ultrasonography measurements. A description of transcranial duplex ultrasonography and phantom development is provided. Measurements were made using a commercially available ultrasound system and cardiopulmonary bypass machine, water phantom and 32% glycerol solution with cornstarch. The experiments showed that the cerebral blood vessel condition in artificial circulation affects transcranial duple
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5

Yambe, T., S. Nanka, S. Naganuma, et al. "Can the Artificial Heart Make the Circulation Become Fractal?" International Journal of Artificial Organs 18, no. 4 (1995): 190–96. http://dx.doi.org/10.1177/039139889501800403.

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In order to analyze the hemodynamic parameters in prosthetic circulation as an entity and not as decomposed parts, non linear mathematical analyzing techniques, including the fractal dimension analyzing theory, were utilized. Two pneumatically actuated ventricular assist devices were implanted, as biventricular bypasses (BVB), in chronic animal experiments, using four healthy adult goats. For the comparison between the natural and prosthetic circulation in the same animals, the BVB type complete prosthetic circulation model with ventricular fibrillation, was adopted. All hemodynamic parameters
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6

Radіushin, D. О., О. А. Loskutov, and P. V. Кіstruga. "Prophylaxis of cerebro-vascular complications while performance of aorto-coronary shunting in conditions of artificial blood circulation." Klinicheskaia khirurgiia 86, no. 6 (2019): 14–18. http://dx.doi.org/10.26779/2522-1396.2019.06.14.

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Objective. To estimate the efficacy of application of vasodilator nitroglycerine on background of high volumic speed of perfusion for prophylaxis of the cerebral vessels microembolism while performance of the aorto-coronary shunting (ACSH) operations in conditions of artificial blood circulation.
 Маterials and methods. The investigation was conducted in 72 patients, suffering the ischemic heart disease, to whom aorto-coronary shunting operation was accomplished in conditions of artificial blood circulation in the Odessa Regional Clinical Hospital. Median age of the patients have constitu
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7

Gumenyuk, B. M. "The anemia correction in chronic diseases in perioperative period while performing prosthesis of aortal valve." Klinicheskaia khirurgiia 87, no. 5-6 (2020): 30–35. http://dx.doi.org/10.26779/2522-1396.2020.5-6.30.

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Objective. To determine the impact of preoperative correction, using hydroxide of iron (III) erythropoietin, in patients, having the heart aortal failures, complicated by the chronic diseases anemia, on the postoperative anemia after doing the aortal valve prosthesis in accordance to the blood-preserving technology in the artificial blood circulation conditions.
 Materials and metods. The investigation was conducted in 83 patients, to whom the aortal valve prosthesis was performed with a blood-preserving technology in conditions of artificial blood circulation without application of hemo-
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8

Watanabe, Ai, and Norihisa Miki. "Connecting Mechanism for Artificial Blood Vessels with High Biocompatibility." Micromachines 10, no. 7 (2019): 429. http://dx.doi.org/10.3390/mi10070429.

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This paper proposes a connecting mechanism for artificial vessels, which can be attached/detached with ease and does not deteriorate the biocompatibility of the vessels at the joint. The inner surface of the artificial vessels is designed to have high biocompatibility. In order to make the best of the property, the proposed connecting mechanism contacts and fixes the two artificial vessels whose contacting edges are turned inside out. In this manner, blood flowing inside the vessels only has contact with the biocompatible surface. The biocompatibility, or biofouling at the joint was investigat
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9

Lautier, A., D. Gaillard, A. M. Juvin, J. P. Gille, J. C. Sargentini, and T. Dehe. "Monitoring of Blood Gases during Extracorporeal Circulation with an Artificial Lung." International Journal of Artificial Organs 13, no. 2 (1990): 117–24. http://dx.doi.org/10.1177/039139889001300212.

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10

Tasakorn, M., N. Suwanpayak, and P. Preecha Yupapin. "Blood Circulation Network Incorporation an Artificial Bone for Real Time Operation." Advanced Materials Research 506 (April 2012): 102–5. http://dx.doi.org/10.4028/www.scientific.net/amr.506.102.

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We propose the use of molecular buffers and networks for blood circulation in Haversian and Volkmanns canals to deliver the nutrient, drug and other essential substances in the regeneration process of bone and soft tissue. By using the dynamic optical tweezers generated within a PANDA ring resonator, the required molecules can be trapped and transported within the designed neural networks, in which the required substances can perform within the required region before reaching the required destinations. The advantage of the proposed system is that system, which can perform within the tiny syste
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11

Ul'yanov, N. A., and L. N. Radionova. "Implementation characteristics of the pulsed mode in artificial blood-circulation apparatus." Biomedical Engineering 23, no. 1 (1989): 22–25. http://dx.doi.org/10.1007/bf00560597.

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12

Gumeniuk, B. M., V. V. Popov, A. K. Logutov, and E. V. Aksenov. "The Impact of Complex Preoperative Preparation of Patients with Aortic Heart Diseases on the Level of Postoperative Anemia." Ukrainian journal of cardiovascular surgery, no. 2 (39) (April 3, 2020): 37–42. http://dx.doi.org/10.30702/ujcvs/20.3905/026037-042.

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In patients undergoing surgical treatment of aortic heart defects under artificial circulation, pre-operative correction of serum iron levels, and application of blood-saving techniques during surgery reduce the level of postoperative anemia.
 The aim. To investigate the combined influence of preoperative correction of serum iron levels and blood-saving techniques in the early postoperative anemia in the surgical treatment of aortic heart defects under artificial circulation.
 Material and methods. This study involves 133 patients with acquired aortic heart diseases undergoing surgic
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13

Hardy, Eugenio, Hassan Sarker, and Carlos Fernandez-Patron. "Could a Non-Cellular Molecular Interactome in the Blood Circulation Influence Pathogens’ Infectivity?" Cells 12, no. 13 (2023): 1699. http://dx.doi.org/10.3390/cells12131699.

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We advance the notion that much like artificial nanoparticles, relatively more complex biological entities with nanometric dimensions such as pathogens (viruses, bacteria, and other microorganisms) may also acquire a biomolecular corona upon entering the blood circulation of an organism. We view this biomolecular corona as a component of a much broader non-cellular blood interactome that can be highly specific to the organism, akin to components of the innate immune response to an invading pathogen. We review published supporting data and generalize these notions from artificial nanoparticles
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14

Nakazawa, K., H. Ijima, J. Fukuda, et al. "Development of a Hybrid Artificial Liver Using Polyurethane Foam / Hepatocyte Spheroid Culture in a Preclinical Pig Experiment." International Journal of Artificial Organs 25, no. 1 (2002): 51–60. http://dx.doi.org/10.1177/039139880202500109.

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We describe a preclinical study of our original hybrid artificial liver support system (HALSS) for a clinical trial. We designed a HALSS comprising a multi-capillary polyurethane foam packed-bed module (MC-PUF module) containing a total 200 g (2 × 1010 cells) porcine hepatocytes, and an extracorporeal circulation device. Almost all porcine hepatocytes in the MC-PUF module formed many spherical multicellular aggregates (spheroids). This extracorporeal circulation device was improved to promote solute exchange between a living body and a MC-PUF module by including a plasma bypass line in the cir
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15

Barygin, E. K., A. O. Marichev, A. M. Radovskiy, et al. "Nitric oxide delivery into oxygenators of artificial and assisted blood circulation. Current state and prospects of technology development (literature review)." Messenger of ANESTHESIOLOGY AND RESUSCITATION 22, no. 1 (2025): 151–62. https://doi.org/10.24884/2078-5658-2025-22-1-151-162.

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The use of cardiopulmonary bypass (CPB) technologies is often associated with ischemic and re-perfusion injury to the myocardium. The contact of patient’s blood with the surface of the extracorporeal circuit leads to platelets activation and often triggers a systemic inflammatory reaction. Nitric oxide (NO) is a signal molecule produced by the endothelium of blood vessels. Under normal circumstances, it prevents excessive activation and aggregation of platelets, thus providing an organ-protective effect. Currently, there is a considerable amount of data available about positive effects of use
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16

Bober, V. V., S. E. Domnin, and V. V. Pichugin. "Protection of lungs in the course of surgeries with artificial blood circulation." Medical almanac, no. 3 (2017): 123–27. http://dx.doi.org/10.21145/2499-9954-2017-3-123-127.

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17

Rykov, S. O., O. A. Venediktova, and S. Yu Mogilevskyy. "Features of retinal vascular occlusion after cardiac surgeries using artificial blood circulation." Archive of Ukrainian Ophthalmology 8, no. 1 (2020): 56–63. http://dx.doi.org/10.22141/2309-8147.8.1.2020.200737.

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18

Kurashov, M. S., A. S. Kulik, V. N. Levanovich, D. V. Motovilov, and A. V. Marochkov. "Dynamics of hemoglobin and hematocrit in patients during open-heart surgery using artificial circulation." Health and Ecology Issues 21, no. 2 (2024): 30–37. http://dx.doi.org/10.51523/2708-6011.2024-21-2-04.

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Objective. Determination of the dynamics of hemoglobin and hematocrit concentrations in blood, assessment of interrelation between these indicators and blood loss in patients undergoing open-heart surgery using artificial circulation.Materials and methods. A group of 67 patients requiring open-heart surgery using artificial circulation was formed. Each patient was assessed for the dynamics of hemoglobin and hematocrit concentrations in the analysis of the acid-base state of arterial blood at 7 stages of hospital treatment.Results. The dynamics of changes in the content of hemoglobin and erythr
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19

Gajbhiye, Yashpal Aniruddha. "Titanium-Based Artificial Heart." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 01 (2025): 1–9. https://doi.org/10.55041/ijsrem41015.

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This paper presents the design and analysis of a titanium-based artificial heart that functions as a complete replacement for the human heart. The proposed design incorporates a compact motor for blood circulation and is powered by a combination of solar energy and a backup battery system to ensure continuous operation. By adopting advanced materials and design principles, with modifications in dimensions and energy integration, this study aims to offer a sustainable and durable solution for patients requiring total heart replacement. Computational analyses assess hemodynamic performance, stru
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20

Ardiyani, Dini, and Zen Ahmad. "The Role of Extracorporeal Membrane Oxygenation on Acute Respiratory Distress Syndrome." Bioscientia Medicina : Journal of Biomedicine and Translational Research 5, no. 10 (2021): 953–60. http://dx.doi.org/10.32539/bsm.v5i10.362.

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Acute lung injury and acute respiratory distress syndrome are characterized by rapid-onset respiratory failure following a variety of direct and indirect insults to the parenchyma or vasculature of the lungs. Extracorporeal membrane oxygenation is a form of extracorporeal life support where an external artificial circulator carries venous blood from the patient to a gas exchange device (oxygenator) where blood becomes enriched with oxygen and has carbon dioxide removed. This blood then re-enters the patients circulation. The potential advantages of ECMO over conventional manajement may extend
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21

Ardiyani, Dini, and Zen Ahmad. "The Role of Extracorporeal Membrane Oxygenation on Acute Respiratory Distress Syndrome." Bioscientia Medicina : Journal of Biomedicine and Translational Research 5, no. 4 (2021): 890–97. http://dx.doi.org/10.32539/bsm.v5i4.362.

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Acute lung injury and acute respiratory distress syndrome are characterized by rapid-onset respiratory failure following a variety of direct and indirect insults to the parenchyma or vasculature of the lungs. Extracorporeal membrane oxygenation is a form of extracorporeal life support where an external artificial circulator carries venous blood from the patient to a gas exchange device (oxygenator) where blood becomes enriched with oxygen and has carbon dioxide removed. This blood then re-enters the patients circulation. The potential advantages of ECMO over conventional manajement may extend
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22

Philpot, Steve, and David Anderson. "The ethical and legal implications of the Human Tissue Amendment Act 2020 (Vic)." Critical Care and Resuscitation 23, no. 3 (2021): 245–47. http://dx.doi.org/10.51893/2021.3.pov.

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The Human Tissue Act 1982 (Vic) has recently been amended by the Human Tissue Amendment Act 2020(Vic). In an effort to better reflect the modern practice of organ donation, the intention of the amendment is to include a process for the authorisation of ante-mortem procedures in patients being considered for organ donation after circulatory determination of death(DCDD). As part of this process, the amendment introduces a new requirement for consent for such ante-mortem procedures, and specifies that: A designated officer for a hospital must not give an authority … in respect of a person unless,
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23

Radiushyn, D. A., O. A. Loskutov, A. M. Druzhina, and V. G. Kolesnikov. "Microembolization of Cerebral Blood Flow during Coronary Artery Bypass Grafting in Conditions of Artificial Blood Circulation." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 3, no. 6 (2018): 139–46. http://dx.doi.org/10.26693/jmbs03.06.139.

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24

Knierbein, B., H. Reul, R. Eilers, M. Lange, R. Kaufmann, and G. Rau. "Compact Mock Loops of the Systemic and Pulmonary Circulation for Blood Pump Testing." International Journal of Artificial Organs 15, no. 1 (1992): 40–48. http://dx.doi.org/10.1177/039139889201500108.

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Mock loops are an important tool for in vitro investigations of artificial blood pumps. The simple windkessel, throttle, and atrium principle was used for the mock loop design presented. The components of the systemic and the pulmonary mock loop were designed according to calculated numerical simulation parameters. The loops offer a compact design and simple handling. For simulating biventricular assist or total artificial heart (TAH), both loops can be coupled correspondingly. The numerical simulation and the first results with the loops show very good similarity to physiological data of syst
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25

Maksimovich, E. N., T. P. Pronko, I. E. Guliay, and V. A. Snezhitsky. "The NO Level after Coronary Artery Bypass Graft under the Conditions of Artificial Circulation." Health and Ecology Issues, no. 4 (December 28, 2019): 48–52. http://dx.doi.org/10.51523/2708-6011.2019-16-4-9.

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Objective: to study the nature of changes in the content of stable metabolites of nitric oxide (NOx) - nitrites and nitrates - in the blood of patients after coronary artery bypass graft (CABG) under the conditions of artificial circulation.Material and methods. Depending on the level of [Hb] in the blood plasma, the patients with CABG surgery were divided into three groups: 1 - without IOH (Hb ≤ 0.1 g/l), n = 43, 2 - with low IOH (l IOH, Hb > 0.1 g/l and < 0.5 g/l, n = 42), 3 - with high IOH (hIOH, Hb ≥ 0.5 g/l, n = 38). The level of NOx was determined in the blood plasma of the patient
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26

Shereshneva, Marina V., Mikhail V. Ilyin, and Ivan N. Staroverov. "Blood oxidation rate as a predictor of postoperative atrial fibrillation in coronary artery bypass." Человек и его здоровье 26, no. 3 (2023): 36–43. http://dx.doi.org/10.21626/vestnik/2023-3/05.

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The development of postoperative atrial fibrillation (AF) is associated with surgical trauma, neutrophil activation, pro-inflammatory cytokine release and oxidative stress. Objective: assessment of the prognostic significance of determining blood oxidation rate in relation to the risk of developing atrial fibrillation in the postoperative period during coronary artery bypass surgery. Material and methods. The study included 68 patients with stable coronary heart disease (CHD) who underwent coronary artery bypass surgery under artificial circulation (On-pump), parallel artificial circulation an
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27

Wang, Shigang, Bartley P. Griffith, and Zhongjun J. Wu. "Device-Induced Hemostatic Disorders in Mechanically Assisted Circulation." Clinical and Applied Thrombosis/Hemostasis 27 (January 1, 2021): 107602962098237. http://dx.doi.org/10.1177/1076029620982374.

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Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular assistance with a ventricular assist device (VAD) or on extracorporeal membrane oxygenation (ECMO) with a pump-oxygenator system. While MAC provides short-term (days to weeks) support and long-term (months to years) for the heart and/or lungs, the blood is inevitably exposed to non-physiological shear stress (NPSS) due to mechanical pumping action and in contact with artificial surfaces. NPSS is well known to cause blood
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28

R.R., Yarbekov, and Ilkhomov O.E. "APPLICATION OF DIFFERENT MINI-INVASIVE TECHNOLOGY IN CARDIAC SURGERY." American Journal of Medical Sciences and Pharmaceutical Research 6, no. 7 (2024): 68–74. http://dx.doi.org/10.37547/tajmspr/volume06issue07-09.

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In the modern era of cardiac surgery, most operations have been performed via midline sternotomy using artificial circulation. However, this paradigm is changing as minimally invasive techniques are increasingly utilized in cardiovascular surgery. Advances in patient assessment, instrumentation, and operative techniques have allowed surgeons to perform a wide range of complex operations through smaller incisions and, in some cases, without artificial circulation. Given that patients desire less invasive surgeries and the literature supports reduced blood loss, shorter hospital stays, less post
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29

Mizuno, H., J. Isobe, S. Matsunobe, T. Nakamura, Y. Shimizu, and S. Hitomi. "A liquid-liquid blood-gas exchange for the treatment of acute respiratory failure: A new blood gas exchange using artificial blood as an oxygen carrier." International Journal of Artificial Organs 17, no. 11 (1994): 609–15. http://dx.doi.org/10.1177/039139889401701110.

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A new liquid-liquid blood gas exchange system was investigated using a veno-venous low flow extracorporeal circuit. A 2 m2 hollow fiber dialyzer served as the interface of the blood and oxygen carrier (a 38 percent FC-43, perfluorocarbon emulsion in a buffered electrolyte solution), which was continuously recycled through a bubble oxygenator. Experiments were performed on five mongrel dogs under general anesthesia. Upon the arrest of spontaneous ventilation, the dogs' lungs were inflated with 50% oxygen gas under a positive pressure of 10 cmH2O. After 10 min of apnea the dogs' PaO2 decreased t
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30

Huang, Nan, Ping Yang, Yong Xiang Leng, et al. "Improving Blood Compatibility of Cardiovascular Devices by Surface Modification." Key Engineering Materials 342-343 (July 2007): 801–4. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.801.

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This paper presents recent activities on the surface modification of blood contacting biomaterials and devices in the author’s laboratory. Surface coating of inorganic films on materials for artificial heart valves, ventricular pumps and coronary stents, such as titanium, stainless steel and low temperature isotropic pryolitc carbon, etc, shows a significant improvement in the anticoagulation behavior. Further, the formation of functional groups such as hydroxyl or amino groups and the binding of biomolecules as well as seeding of endothelial cell shows the promise of biomimetic surface format
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31

Maher, Dermot P. "Initial Experience with IV Ketamine Infusion for Treatment of Post Sternotomy Pain in a Patient with a Total Artificial Heart." May 2015 3;18, no. 3;5 (2015): E425—E427. http://dx.doi.org/10.36076/ppj.2015/18/e425.

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The implantation of total artificial hearts (TAHs) via midline sternotomy for the treatment of severe biventricular cardiac dysfunction is associated with complex postoperative pain management. Ketamaine increases blood pressure by raising sympathetic outflow and cardiac ouput; however, ketamine is a direct vasodilator on isolated arterial tissues. In the setting of a TAH with a mechanically fixed cardiac output, a ketamine infusion for postoperative pain control has the potential to decrease blood pressure due to direct arterial vasodilation. We present the initial experience with a ketamine
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32

Loskutov, О. А., О. M. Druzhyna, and B. М. Todurov. "Neurocognitive dysfunctions in the remote postoperative period during cardiac surgery with artificial blood circulation." Ukrainian Journal of Cardiology, no. 6 (December 2018): 72–77. http://dx.doi.org/10.31928/1608-635x-2018.6.7277.

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33

Rykov, S. O., and O. A. Venediktova. "MARKERS OF APPEARANCE OF RETINAL VEIN OCCLUSION AFTER CARDIOSURGICAL INTERVENTIONS USING ARTIFICIAL BLOOD CIRCULATION." Bulletin of Problems Biology and Medicine 1, no. 1 (2020): 193. http://dx.doi.org/10.29254/2077-4214-2020-1-155-193-199.

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34

Körfer, S., S. Klaus, and K. Mottaghy. "Application of Taylor Vortices in Hemocompatibility Investigations." International Journal of Artificial Organs 26, no. 4 (2003): 331–38. http://dx.doi.org/10.1177/039139880302600408.

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Background Artificial organs, implants and extracorporeal circulation affect the physiological flow characteristics of blood as a liquid organ. These artificial systems consist of a wide variety of biomaterials with different geometries and, therefore, with their own flow properties. Secondary flow also occurs in extra – as well as in intracorporeal circulation. Methods In order to investigate the influence of vortical flow conditions a modified Taylor-Couette system was introduced. It consisted of two coaxial cylinders whose surfaces were the target of investigation. The annular gap was fille
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35

Medvedev, V. N., and G. I. Kharitonov. "Dynamics of the changes of luminoldependent chemoluminescence of blood in patients with heart diseases operated in artificial blood circulation." Kazan medical journal 79, no. 4 (1998): 264–67. http://dx.doi.org/10.17816/kazmj64426.

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The search of the prognostic criterion of postperfusion period course is performed. The informativity of one of the nonspecific organism protection indices luminoldependent chemoluminescence of blood is estimated. Spontaneous chemoluminescence expresses phagocytes activity by the intensity of hydrogen peroxide generation. Stimulated chemoluminescence allows to establish the functional leykocytes reserve. As many as 54 patients with heart diseases are examined in dynamics. The increase of both of chemoluminescence types is observed in the cases of the uncomplicated course, during artificial blo
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36

El Atik, Abd El Fattah A., and Ashgan S. wahba. "Topological approaches of graphs and their applications by neighborhood systems and rough sets." Journal of Intelligent & Fuzzy Systems 39, no. 5 (2020): 6979–92. http://dx.doi.org/10.3233/jifs-200126.

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Rough set theory is used in simple directed graphs to study nano topology. Adjacent vertices was used in digraphs only to define their neighborhoods. Four types of neighborhood systems for vertices are introduced in this article which depend on both adjacent vertices and associated edges. Additionally, the generalization of some notions presented by Pawlak and Lellis Thivagar and some of their properties are investigated. Finally, we present a new model of a blood circulation system of the human heart based on blood paths. Also, different kinds of topological separation axioms are presented an
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37

Kupryashov, A. A., E. V. Kuksina, G. A. Kchycheva, and G. A. Haydarov. "Impact of anemia on outcomes in on-pump coronary artery bypass surgery patients." Kardiologiia 61, no. 11 (2021): 42–48. http://dx.doi.org/10.18087/cardio.2021.11.n1802.

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Aim To study the contribution of preoperative anemia to the prognosis of adverse clinical events (mortality, complications, transfusion) in patients with ischemic heart disease (IHD) after myocardial revascularization in the conditions of artificial circulation.Material and methods This retrospective cohort study included 1 133 patients with IHD who had undergone isolated myocardial revascularization in the conditions of artificial circulation in 2019. The primary endpoints were mortality and a composite endpoint that included, in addition to mortality, cases of acute coronary syndrome, heart,
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38

Leth-Møller, Magnus, Christina Søndergaard Duvald, Sofie Stampe, et al. "Transplacental Transport of Artificial Sweeteners." Nutrients 15, no. 9 (2023): 2063. http://dx.doi.org/10.3390/nu15092063.

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The prevalence of obesity is increasing, and the origins of obesity and metabolic dysfunction may be traced back to fetal life. Currently, overweight pregnant women are advised to substitute sugar-sweetened beverages with diet drinks containing artificial sweeteners. Recent evidence suggests that the consumption of artificial sweeteners during pregnancy increases the risk of obesity in the child, but the mechanism is unknown. We hypothesized the transportation of artificial sweeteners across the placenta into the fetal circulation and the amniotic fluid. We included 19 pregnant women who were
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Liang, Loh Quo, Kok Yin Hui, Nur Hazreen Mohd Hasni, and Mohd Azrul Hisham Mohd Adib. "Development of Heart Simulator (Heart-S) on the Left Ventricle for Measuring the Blood Circulation during Cardiac Cycle." Journal of Biomimetics, Biomaterials and Biomedical Engineering 36 (March 2018): 78–83. http://dx.doi.org/10.4028/www.scientific.net/jbbbe.36.78.

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Heart is a complex structure which acts as a blood pump in mammal’s body. It is important to have detail study for the heart structure. Modeling of heart structure gives a better understanding and figure of the heart valve’s movement as well as the fluid flow movement in the heart chamber. In this paper, the heart simulator (Heart-S) on the left ventricle for measuring the blood circulation during cardiac cycle was proposed. Throughout the experimental modeling of heart valve structure by using rhythmic fluid flow in a closed chamber, the relationship between heart valve elasticity and heart v
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40

О. П. Мазуренко, П. Надзякевич, О. А. Лоскутов, and Л. В. Згржебловська. "BLOOD COAGULATION SYSTEM AND PERSONALIZATION OF TREATMENT IN PATIENTS WITH IMPLANTED SYSTEM OF LEFT VENTRICLE ASSIST DEVICE IN THE EARLY POSTOPERATIVE PERIOD." PAIN, ANAESTHESIA & INTENSIVE CARE, no. 1(90) (February 3, 2020): 43–48. http://dx.doi.org/10.25284/2519-2078.1(90).2020.193909.

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The work is devoted to the study of the blood coagulation system and the correction of its indicators with a personalized anticoagulant target therapy in the early postoperative period to ten patients with implanted left ventricle assist devices for mechanical circulation support in the Silesian Center Heart Diseases, according to a bilateral agreement with the National Medical Academy of Postgraduate Education named after P. Shupik. The study included ten patients who were implanted in the Silesian Center for Heart Disease from March 11, 2016 to Nov 22, 2017, devices for mechanical support of
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41

Kostiantyn, Mykhnevych. "Energy of blood circulation in primary reduction of myocardial contractility." ScienceRise: Medical Science, no. 5(38) (September 30, 2020): 10–14. https://doi.org/10.15587/2519-4798.2020.213516.

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<strong>The aim</strong>: to study the energy parameters of the circulatory system in heart failure in patients with acute coronary syndrome (ACS) against the background of coronary artery bypass grafting (CABG), depending on the degree of myocardial contractility decrease. <strong>Materials and methods</strong>. In 48 patients with ACS in the perioperative period energy parameters of blood circulation have been determined: flow power (FP), oxygen reserve (OR) and circulatory reserve (CR). FP reflects the useful power of the myocardium, OR &ndash; the correspondence of oxygen absorption by tis
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42

Hasyar, Andi Rizky Arbaim, Haerani Rasyid, Irfan Idris, and Irawan Yusuf. "Effect of Artificial Carbon Dioxide-Rich Water Immersion on Peripheral Blood Flow in Healthy Volunteers: Preliminary Study about Artificial Carbon Dioxide-Rich Water." Open Access Macedonian Journal of Medical Sciences 9, A (2021): 527–31. http://dx.doi.org/10.3889/oamjms.2021.6591.

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BACKGROUND: Peripheral blood circulation disorder is one of the global health problems. Balneotherapy that uses CO2 springs may be one of the complementary treatment options. The device to produce artificial CO2-rich water is needed to achieve an improvement effect, at least almost like the improvement effect of natural balneotherapy. AIM: This study aims to investigate the effect of artificial CO2-rich water immersion on peripheral blood flow using Bicarbonated JesC CREA BC-2000. METHODS AND MATERIALS: Thirty-nine healthy volunteers participated in this study. Each subject immersed both of th
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43

Boschetti, F., F. M. Montevecchi, and R. Fumero. "Virtual Extracorporeal Circulation Process." International Journal of Artificial Organs 20, no. 6 (1997): 341–51. http://dx.doi.org/10.1177/039139889702000608.

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Virtual instruments for an extracorporeal circulation (ECC) process were developed to simulate the reactions of a patient to different artificial perfusion conditions. The computer simulation of the patient takes into account the hydraulic, volume, thermal and biochemical phenomena and their interaction with the devices involved in ECC (cannulae dimensions, oxygenator and filter types, pulsatile or continuous pump and thermal exchangers). On the basis of the patient's initialisation data (height, weight, Ht) and perfusion variables (pump flow rate, water temperature, gas flow rate and composit
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44

João Vitor Mendes Pinto dos Santos and Thamiles Rodrigues de Melo. "Machine Learning-Based Cardiac Arrhythmia Detection in Electrocardiogram Signals." JOURNAL OF BIOENGINEERING, TECHNOLOGIES AND HEALTH 7, no. 2 (2024): 113–16. http://dx.doi.org/10.34178/jbth.v7i2.378.

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The cardiovascular system is vital for human physiology, regulating blood circulation. Cardiovascular Diseases (CVDs), including cardiac arrhythmias, can disrupt the heartbeat rhythm, impacting blood circulation. Black-box computational modeling of this system can facilitate the development of novel methods and devices to assist in diagnosing and treating CVDs. Artificial Neural Networks (ANNs) represent an effective black-box approach. Implementation involves selecting a database, separating training and test sets, and defining the model structure. The MIT-BIH database is commonly utilized to
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Tomarchio, Emilia, Francesca Momigliano, Lorenzo Giosa, Patrick Duncan Collins, Nicholas A. Barrett, and Luigi Camporota. "The intricate physiology of veno-venous extracorporeal membrane oxygenation: an overview for clinicians." Perfusion 39, no. 1_suppl (2024): 49S—65S. http://dx.doi.org/10.1177/02676591241238156.

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During veno-venous extracorporeal membrane oxygenation (V-V ECMO), blood is drained from the central venous circulation to be oxygenated and decarbonated by an artificial lung. It is then reinfused into the right heart and pulmonary circulation where further gas-exchange occurs. Each of these steps is characterized by a peculiar physiology that this manuscript analyses, with the aim of providing bedside tools for clinical care: we begin by describing the factors that affect the efficiency of blood drainage, such as patient and cannulae position, fluid status, cardiac output and ventilatory str
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46

Zelenchuk, O. V., A. V. Khokhlov, A. Yu Shkandala, et al. "Hybrid surgery for aneurysm of the arch and descending part of the aorta. Right-left subclavian bypass as a variant of subtotal debranching." Cardiac surgery and interventional cardiology, no. 1-2 (September 19, 2023): 77–87. http://dx.doi.org/10.31928/2305-3127-2023.1-2.7787.

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The article presents the experience of our team in various surgical methods of treating aortic pathology. Surgical pathology of the thoracic aorta, namely aneurysms and dissections, remains controversial for the «heart team». In recent years, endovascular aortic replacement (TEVAR) has proven itself as a treatment option for many aortic diseases with a mortality rate up to 7.5 %. According to the latest clinical recommendations, TEVAR has become the method of choice in the treatment of acute aortic dissection, showing better results compared to medical therapy and open surgery. However, the en
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47

Kratkou, K. O., and V. N. Valentyukevich. "APPLICATION OF THE METHOD OF EXTRACORPOREAL AUTOHEMOMAGNETIC THERAPY FOR THE PURPOSE OF CORRECTION OF HEMODYNAMIC DISORDERS IN THE INTRAOPERATIVE PERIOD WHEN PERFORMING CORONARY BYPASS UNDER ARTIFICIAL CIRCULATION." Journal of the Grodno State Medical University 22, no. 1 (2024): 51–55. http://dx.doi.org/10.25298/2221-8785-2024-22-1-51-55.

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Purpose of the study. To evaluate the effect of extracorporeal autohemomagnetic therapy on the parameters of central hemodynamics during surgical intervention for myocardial revascularization (aortocoronary and mammary coronary bypass surgery) under conditions of artificial circulation. Material and methods. The parameters of invasive hemodynamics of 100 patients who were treated in anesthesiology and intensive care units were studied. All patients were divided into 2 groups. Group 1 (50 people) received standard anesthesia (multicomponent balanced anesthesia) for coronary artery bypass grafti
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48

Lozovyi, Oleksii A., and Kostiantyn V. Rudenko. "Surgical Treatment of Atrial Fibrillation and Flutter in Patients with Atrial Septal Defects." Ukrainian Journal of Cardiovascular Surgery 32, no. 2 (2024): 113–19. http://dx.doi.org/10.30702/ujcvs/24.32(02)/lr024-113119.

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The article analyzes the results of surgical treatment of atrial fibrillation or flutter in patients with an atrial septal defect (ASD). The aim. To increase the effectiveness of surgical treatment of concomitant atrial fibrillation (AF) / atrial flutter (AFL) in patients with ASD. Materials and methods. The study included 124 people, with a mean age of 38.3 ± 4.4 years. The patients were divided into 3 groups. Group 1 included patients with ASD and concomitant AF/AFL who underwent closure of the ASD and radiofrequency ablation, while group 2 included patients with ASD and concomitant AF/AFL w
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49

Alifimoff, James K., Peter Safar, and Nicholas Bircher. "Limitations of Abdominal Binding during CPR." Prehospital and Disaster Medicine 1, S1 (1985): 227–29. http://dx.doi.org/10.1017/s1049023x00044575.

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Sudden cardiac death is the number one killer in the western world. In the USA alone, CPR attempts are justified in 200,000 cases per year. Recovery of brain function requires immediate initiation and uninterrupted maintenance of artificial ventilation and circulation by basic life support (BLS) until restoration of spontaneous circulation (ROSC) is possible with advanced life support (ALS). Presently recommended standard CPR (SCPR) produces only 6–30% of normal common carotid blood flow. For this reason, a more effective method of prolonged CPR-BLS is necessary in the absence of ALS ambulance
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Zinchuk, P. V., A. A. Ivkin, E. V. Grigoriev, and D. G. Balakhnin. "The role of nitric oxide in nephroprotection during surgical correction of congenital heart disease in children (literature review)." Messenger of ANESTHESIOLOGY AND RESUSCITATION 21, no. 6 (2024): 122–29. https://doi.org/10.24884/2078-5658-2024-21-6-122-129.

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Introduction. The need to develop effective methods of renal protection during cardiac surgical interventions is dictated by the progressive increase of acute kidney injury (CS-AKI) in children, which is associated with immaturity of renal function and damaging factors of cardiopulmonary bypass (CPB): activation of systemic inflammation response, hypothermia, hemodilution, hemolysis, transfusion of donor blood components, hypoxia/hyperoxia. CS-AKI in this population results in worsening of both early and long-term patient prognosis. However, there is no universally accepted strategy for nephro
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