Academic literature on the topic 'Artificial Yeast Chromosomes'

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Journal articles on the topic "Artificial Yeast Chromosomes"

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Ross, L. O., D. Treco, A. Nicolas, J. W. Szostak, and D. Dawson. "Meiotic recombination on artificial chromosomes in yeast." Genetics 131, no. 3 (July 1, 1992): 541–50. http://dx.doi.org/10.1093/genetics/131.3.541.

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Abstract We have examined the meiotic recombination characteristics of artificial chromosomes in Saccharomyces cerevisiae. Our experiments were carried out using minichromosome derivatives of yeast chromosome III and yeast artificial chromosomes composed primarily of bacteriophage lambda DNA. Tetrad analysis revealed that the artificial chromosomes exhibit very low levels of meiotic recombination. However, when a 12.5-kbp fragment from yeast chromosome VIII was inserted into the right arm of the artificial chromosome, recombination within that arm mimicked the recombination characteristics of the fragment in its natural context including the ability of crossovers to ensure meiotic disjunction. Both crossing over and gene conversion (within the ARG4 gene contained within the fragment) were measured in the experiments. Similarly, a 55-kbp region from chromosome III carried on a minichromosome showed crossover behavior indistinguishable from that seen when it is carried on chromosome III. We discuss the notion that, in yeast, meiotic recombination behavior is determined locally by small chromosomal regions that function free of the influence of the chromosome as a whole.
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Blackburn, Elizabeth H. "Artificial chromosomes in yeast." Trends in Genetics 1 (January 1985): 8–12. http://dx.doi.org/10.1016/0168-9525(85)90007-1.

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Sambrook, Joseph, and David W. Russell. "Working with Yeast Artificial Chromosomes." Cold Spring Harbor Protocols 2006, no. 1 (June 2006): pdb.prot3297. http://dx.doi.org/10.1101/pdb.prot3297.

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Selleri, Licia, Gary G. Hermanson, James H. Eubanks, and Glen A. Evans. "Chromosomal in situ hybridization using yeast artificial chromosomes." Genetic Analysis: Biomolecular Engineering 8, no. 2 (April 1991): 59–66. http://dx.doi.org/10.1016/1050-3862(91)90050-2.

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Pavan, W. J., and R. H. Reeves. "Integrative selection of human chromosome-specific yeast artificial chromosomes." Proceedings of the National Academy of Sciences 88, no. 17 (September 1, 1991): 7788–91. http://dx.doi.org/10.1073/pnas.88.17.7788.

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McCormick, M. K., J. H. Shero, M. C. Cheung, Y. W. Kan, P. A. Hieter, and S. E. Antonarakis. "Construction of human chromosome 21-specific yeast artificial chromosomes." Proceedings of the National Academy of Sciences 86, no. 24 (December 1, 1989): 9991–95. http://dx.doi.org/10.1073/pnas.86.24.9991.

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Coulson, Alan, Robert Waterston, Jane Kiff, John Sulston, and Yuji Kohara. "Genome linking with yeast artificial chromosomes." Nature 335, no. 6186 (September 1988): 184–86. http://dx.doi.org/10.1038/335184a0.

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Ragoussis, Jiannis, John Trowsdale, and David Markie. "Mitotic recombination of yeast artificial chromosomes." Nucleic Acids Research 20, no. 12 (1992): 3135–38. http://dx.doi.org/10.1093/nar/20.12.3135.

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Cai, H., P. Kiefel, J. Yee, and I. Duncan. "A yeast artificial chromosome clone map of the Drosophila genome." Genetics 136, no. 4 (April 1, 1994): 1385–99. http://dx.doi.org/10.1093/genetics/136.4.1385.

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Abstract We describe the mapping of 979 randomly selected large yeast artificial chromosome (YAC) clones of Drosophila DNA by in situ hybridization to polytene chromosomes. Eight hundred and fifty-five of the clones are euchromatic and have primary hybridization sites in the banded portions of the polytene chromosomes, whereas 124 are heterochromatic and label the chromocenter. The average euchromatic clone contains about 211 kb and, at its primary site, labels eight or nine contiguous polytene bands. Thus, the extent as well as chromosomal position of each clone has been determined. By direct band counts, we estimate our clones provide about 76% coverage of the euchromatin of the major autosomes, and 63% coverage of the X. When previously reported YAC mapping data are combined with ours, euchromatic coverage is extended to about 90% for the autosomes and 82% for the X. The distribution of gap sizes in our map and the coverage achieved are in good agreement with expectations based on the assumption of random coverage, indicating that euchromatic clones are essentially randomly distributed. However, certain gaps in coverage, including the entire fourth chromosome euchromatin, may be significant. Heterochromatic sequences are underrepresented among the YAC clones by two to three fold. This may result, at least in part, from underrepresentation of heterochromatic sequences in adult DNA (the source of most of the clones analyzed), or from clone instability.
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Izvolsky, K. "Yeast artificial chromosome segregation from host chromosomes with similar lengths." Nucleic Acids Research 26, no. 21 (November 1, 1998): 5011–12. http://dx.doi.org/10.1093/nar/26.21.5011.

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Dissertations / Theses on the topic "Artificial Yeast Chromosomes"

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Morroll, Shaun Michael. "Mapping of yeast artificial chromosomes from Arabidopsis chromosome 5." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308922.

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Meaney, Paul James. "Mapping the Plasmodium falciparum genome with yeast artificial chromosomes." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/12640.

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Yeast Artificial Chromosome cloning vectors, with their capacity to maintain up to 1 Mb of cloned DNA in a stable form, have proved extremely useful in mapping the genomes of higher eukaryotes. These vectors possess features which can circumvent some of the problems associated with classical molecular manipulation in Plasmodium falciparum. The research presented in this thesis is aimed at contributing to genome mapping in P. falciparum. The primary objective is the construction of a complete, detailed YAC- based physical map of chromosome 6, with a resolution of 10 Kb. To accomplish this, an 1100 YAC library of the P. falciparum isolate HB3 was constructed. The library contains clones with an average insert size of 100 Kb. Insert DNA is stable when cultured over 100 generations and the library is predicted to have a 4/5 fold genome redundancy, corresponding to 90% of the genome. Chromosome 6 specific YAC's have been isolated and three contigs initiated. Overlapping YAC's have been identified by using Sequence Tagged Site markers obtained from the 5 and 3 ends of each YAC by Inverse PCR. A total of 700 Kb of P. falciparum DNA has been cloned and this has been extensively mapped with seven restriction enzyme. Maps for all available YAC's will be presented. In addition, an attempt has been made to evaluate the degree of stage specific gene expression of cloned DNA within each YAC. The implications of these findings for genome mapping in P. falciparum will be discussed in the thesis.
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Francis, Michael J. "Physical mapping around the SMA gene using yeast artificial chromosomes (YACs)." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259879.

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Davies, Nicholas Paul. "Modification, transfer and expression of yeast artificial chromosomes carrying human immunoglobulin genes." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318326.

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Meyer, Knut. "Positional cloning of the ABI1 locus of Arabidopsis thaliana using yeast artificial chromosomes /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10974.

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White, Jacqueline Katie. "Analysis of human NRAMP, IL8R and V1L1 genes (2q35) using yeast artificial chromosomes." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339595.

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Van, Brabant Anja Josifa. "Characterizing YAC replication : identification and deletion of replication origins within a human DNA insert /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/10274.

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McGuigan, Amanda Jane. "Functional analysis of DNA cloned in yeast artificial chromosomes for replication and centromere function in mammalian cells." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299885.

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Mathrubutham, Umamaheshwar. "An investigation into the use of yeast artificial chromosomes for the identification of origins of replication in human DNA." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296259.

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Buchanan, Christina Diane. "Identification and characterization of a checkpoint triggered by delayed replication in S. cerevisiae /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10253.

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Books on the topic "Artificial Yeast Chromosomes"

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James, Louise Anne. Physical mapping on human chromosome 3 using yeast artificial chromosomes. Manchester: University of Manchester, 1994.

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Tracey, S. M. The effects of yeast artificial chromosomes of the yeast genome. Manchester: UMIST, 1995.

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Heale, S. M. Factors effecting the utility of yeast artificial chromosomes as cloning vectors. Manchester: UMIST, 1993.

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Scherer, Stephen W. Physical mapping of human chromosome 7 with yeast artificial chromosome (YAC) vectors. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1991.

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Scherer, Stephen W. Physical mapping of human chromosome 7 with yeast artificial chromosomes. 1995.

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1944-, Adolph Kenneth W., ed. Microbial gene techniques. San Diego: Academic Press, 1995.

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MacKenzie, Alasdair. YAC Protocols. 2nd ed. Humana Press, 2006.

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Alasdair, MacKenzie, ed. YAC protocols. 2nd ed. Totowa, N.J: Humana Press, 2006.

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Book chapters on the topic "Artificial Yeast Chromosomes"

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Flannery, Angela, and Rakesh Anand. "Yeast Artificial Chromosomes." In Springer Protocols Handbooks, 287–303. Totowa, NJ: Humana Press, 1998. http://dx.doi.org/10.1007/978-1-59259-642-3_24.

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Gooch, Jan W. "Yeast Artificial Chromosomes (YACs)." In Encyclopedic Dictionary of Polymers, 932. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_15129.

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Hiemisch, Holger, Thorsten Umland, Lluís Montoliu, and Günther Schütz. "The Generation of Transgenic Mice with Yeast Artificial Chromosomes." In Microinjection and Transgenesis, 297–308. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80343-7_17.

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Iba, Koh, Sue Gibson, Sue Hugly, Mitsuo Nishimura, and Chris Somerville. "Chromosome Walking in the Region of Arabidopsis fadD Locus Using Yeast Artificial Chromosomes." In Research in Photosynthesis, 55–58. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-009-0383-8_11.

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Peterson, Kenneth R. "Production and Analysis of Transgenic Mice Containing Yeast Artificial Chromosomes." In Genetic Engineering, 235–55. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5925-2_13.

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Serror, Pascale, Vasco Azevedo, and S. Dusko Ehrlich. "An Ordered Collection of Bacillus subtilis DNA Segments in Yeast Artificial Chromosomes." In Bacillus subtilis and Other Gram-Positive Bacteria, 473–74. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818388.ch31.

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Fabb, Stewart A., and Jiannis Ragoussis. "Yeast artificial chromosome vectors." In Molecular and Cell Biology of Human Gene Therapeutics, 104–24. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0547-7_6.

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Martin, Gregory B. "Construction of plant yeast artificial chromosome libraries." In Plant Molecular Biology Manual, 383–99. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0511-8_25.

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Spencer, J. F. T., and D. M. Spencer. "Inside the Inside: Part I: Yeasts and Molecular Biology, a Recipe for Alphabet Soup. Chromosome Structure, Replication, Transcription, and Translation." In Yeasts in Natural and Artificial Habitats, 171–203. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-662-03370-8_11.

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Louis, E. J. "Artificial Chromosomes, Yeast." In Brenner's Encyclopedia of Genetics, 198–99. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-374984-0.00095-4.

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Reports on the topic "Artificial Yeast Chromosomes"

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Antonarakis, S. E. Human chromosome 21: Linkage mapping and cloning in yeast artificial chromosomes. Office of Scientific and Technical Information (OSTI), January 1991. http://dx.doi.org/10.2172/6278130.

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Weier, Heinz-Ulrich G., Karin M. Greulich-Bode, Jenny Wu, and Thomas Duell. Delineating Rearrangements in Single Yeast Artificial Chromosomes by Quantitative DNA Fiber Mapping. Office of Scientific and Technical Information (OSTI), September 2009. http://dx.doi.org/10.2172/982923.

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