Academic literature on the topic 'Artocarpin'

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Journal articles on the topic "Artocarpin"

1

Arung, Enos Tangke, Kuniyoshi Shimizu, and Ryuichiro Kondo. "Artocarpus Plants as a Potential Source of Skin Whitening Agents." Natural Product Communications 6, no. 9 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600943.

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Artocarpus plants have been a focus of constant attention due to the potential for skin whitening agents. In the in vitro experiment, compounds from the Artocarpus plants, such as artocarpanone, norartocarpetin, artocarpesin, artogomezianol, andalasin, artocarbene, and chlorophorin showed tyrosinase inhibitory activity. Structure-activity investigations revealed that the 4-substituted resorcinol moiety in these compounds was responsible for their potent inhibitory activities on tyrosinase. In the in vitro assay, using B16 melanoma cells, the prenylated polyphenols isolated from Artocarpus plan
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2

Suhartati, Tati, Khalimatus Sa’diah, Yandri Yandri, and Sutopo Hadi. "Anticancer Activity Study of Modified Artocarpin Compound from Pudau Plant (Artocarpus kemando Miq.)." Emerging Science Journal 7, no. 3 (2023): 733–43. http://dx.doi.org/10.28991/esj-2023-07-03-05.

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This research is a continuation of the successful isolation of artocarpin from the root of Artocarpus kemando Miq reported in our previous study. In the previous study, the artocarpin was characterized with UV-Vis and FTIR techniques. In this follow-up investigation, the artocarpin was subjected to a transesterification reaction using acetic anhydride and pyridine as catalysts, and the product of the reaction was specified as compound 1. The compound 1 was further characterized with different techniques to gain more complete data and then tested for anticancer activity test against P-388 murin
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3

Sell, Ana Maria, and Celso Paulino da Costa. "Effects of plant lectins on in vitro fibroblast proliferation." Brazilian Archives of Biology and Technology 46, no. 3 (2003): 349–54. http://dx.doi.org/10.1590/s1516-89132003000300006.

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Lectins are carbohydrate-binding proteins that have been isolated from various sources and presented a wide spectrum of biological activities. The effects of four lectins, namely, Phaseolus vulgaris phytohemagglutinin, PHA, wheat germ agglutinin, WGA, Artocarpus integrifolia seed lectins, jacalin and artocarpin, on in vitro fibroblasts proliferation were investigated. The lectins did not influence the initial cell adhesion to the plate. PHA and WGA at 10-20 µg/mL concentrations significantly decreased fibroblasts proliferation. At these concentrations, they caused morphological alterations on
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4

Septama, Abdi Wira, and Eldiza Puji Rahmi, M.Sc. "SYNERGISTIC EFFECT OF COMBINATION BETWEEN CYANOMACLURIN AND ARTOCARPIN FROM ARTOCARPUS HETEROPHYLLUS HEARTWOODS AGAINSTS STREPTOCOCCUS PYOGENES AND STAPHYLOCOCCUS EPIDERMIDIS." Journal of Research in Pharmacy and Pharmaceutical Sciences 1, no. 1 (2022): 21–25. http://dx.doi.org/10.33533/jrpps.v1i1.4250.

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Streptococcus pyogenes and Staphylococcus epidermidis are major problem of human health and may generate antibacterial resistance problem. Flavonoid has been used for the treatment of several ailments including bacterial infection. Artocarpus heterophyllus is a potential source of flavonoid compounds such as artocarpin and cyanomaclurin. The study was conducted to observe synergistic effects between flavonoid compounds against S. pyogenes and S. epidermidis. The antibacterial activity of combination of artocarpin and cyanomaclurin isolated from A. heterophyllus heartwoods were evaluated agains
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5

Suhartati, Tati, Eka Epriyanti, Inggit Borisha, et al. "In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus." Revista de Chimie 71, no. 5 (2020): 400–408. http://dx.doi.org/10.37358/rc.20.5.8150.

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The derivative of flavonoid compounds, artocarpin (1) and artonin M (2), were isolated from the root wood of Artocarpus altilis and from the root bark of A. kemando, respectively. Both plants originated from Lampung, Indonesia. The structure of the two compounds has been carefully determined by physical method and spectroscopy techniques of UV, IR, and NMR. The in vivo antimalarial test of artocarpin showed very good Plasmodium activity in female mice, with ED50 value of 34.88 mg/kg body weight (kgBW), whereas the in vitro antimalarial test of artonin M showed very strong activity with IC50 of
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6

Chowdhury, S., H. Ahmed, and B. P. Chatterjee. "Chemical modification studies of Artocarpus lakoocha lectin artocarpin." Biochimie 73, no. 5 (1991): 563–71. http://dx.doi.org/10.1016/0300-9084(91)90024-u.

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7

Hu, Stephen Chu-Sung, Chi-Ling Lin, Hui-Min Cheng, Gwo-Shing Chen, Chiang-Wen Lee, and Feng-Lin Yen. "Artocarpin Induces Apoptosis in Human Cutaneous Squamous Cell Carcinoma HSC-1 Cells and Its Cytotoxic Activity Is Dependent on Protein-Nutrient Concentration." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/236159.

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Artocarpin, a natural prenylated flavonoid, has been shown to have various biological properties. However, its effects on human cutaneous squamous cell carcinoma (SCC) have not been previously investigated. We set out to determine whether artocarpin has cytotoxic effects on SCC cells and whether its pharmacological activity is dependent on protein-nutrient concentration. Our results showed that treatment of HSC-1 cells (a human cutaneous SCC cell line) with artocarpin decreased cell viability and induced cell apoptosis by increasing caspase 3/7 activity. These effects were more pronounced at l
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8

Suresh, S., P. G. Rani, J. V. Pratap, R. Sankaranarayanan, A. Surolia, and M. Vijayan. "Homology between jacalin and artocarpin from jackfruit (Artocarpus integrifolia) seeds. Partial sequence and preliminary crystallographic studies of artocarpin." Acta Crystallographica Section D Biological Crystallography 53, no. 4 (1997): 469–71. http://dx.doi.org/10.1107/s0907444997000851.

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9

Chowdhury, Sunanda, and Bishnu P. Charterjee. "Artocarpin-galactomannan interaction: Characterization of combining site of artocarpin." Phytochemistry 32, no. 2 (1993): 243–49. http://dx.doi.org/10.1016/s0031-9422(00)94975-6.

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10

Nonpanya, Nongyao, Kittipong Sanookpan, Nicharat Sriratanasak, et al. "Artocarpin Targets Focal Adhesion Kinase-Dependent Epithelial to Mesenchymal Transition and Suppresses Migratory-Associated Integrins in Lung Cancer Cells." Pharmaceutics 13, no. 4 (2021): 554. http://dx.doi.org/10.3390/pharmaceutics13040554.

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Focal adhesion kinase (FAK) controls several cancer aggressive potentials of cell movement and dissemination. As epithelial–mesenchymal transition (EMT) and the migratory-associated integrins, known influencers of metastasis, have been found to be linked with FAK activity, this study unraveled the potential pharmacological effect of artocarpin in targeting FAK resulting in the suppression of EMT and migratory behaviors of lung cancer cells. Treatment with artocarpin was applied at concentrations of 0–10 μM, and the results showed non-cytotoxicity in lung cancer cell lines (A549 and H460), norm
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