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1

Djukic, V. B., J. P. Milovanovic, A. P. Milovanovic, P. D. Stankovic, B. M. Pavlovic, M. M. Folic, and S. R. Blazic. "European laryngological society propose four types endoscopic supraglottic laryngectomy." Acta chirurgica Iugoslavica 56, no. 3 (2009): 85–88. http://dx.doi.org/10.2298/aci0903085d.

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The limited excision addresses small superficial lesions affecting free edge of the epiglottis, the aryepiglottic fold or the superior edge of the arytenoid. The median supraglottic laryngectomy excluding the pre-epiglottic space addresses small superficial T1 lesions of the endolaryngeal epiglottis. The incision line extends to the pre-epiglottic space but does not aim at removing the pre-epiglottic space entirely. The pharyngo-epiglottic folds, aryepiglottic folds, and ventricular folds are preserved. The median supraglottic laryngectomy including the pre-epiglottic space addresses T1 and T2 lesions of the endolaryngeal epiglottis. The entire pre-epiglottic space is removed as far as possible. Depending on extent of the lesion, the resection can include one or two ventricular bands and the aryepiglottic folds. The lateral supraglottic laryngectomy addresses lesions affecting the three folds or T1 and T2 lesions of the aryepiglottic fold. The procedure removes free edge of the epiglottis ipsilateral to the lesion, the area of the three folds and the aryepiglottic fold. The resection can include the inner wall and anterior angle og the pyriform sinus, the entire ventricular fold and the arytenoid (provided it is mobile).
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2

Read, C. Thomas. "Redundant Aryepiglottic Folds May Require Surgical Removal." Chest 108, no. 1 (July 1995): 296. http://dx.doi.org/10.1378/chest.108.1.296-a.

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3

O’Neil, Luke M., and Niall D. Jefferson. "Direct Visualization of Laryngeal Mucociliary Clearance in Adults." Annals of Otology, Rhinology & Laryngology 128, no. 11 (July 4, 2019): 1048–53. http://dx.doi.org/10.1177/0003489419859376.

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Objectives:Mucociliary clearance is a protective mechanism of the respiratory tract that facilitates the removal of foreign particles and microorganisms. There is a paucity of data on the mucociliary clearance in the adult larynx. Our study aims to visualize and describe the mucociliary clearance of the adult larynx in healthy subjects.Methodology:Subjects were identified from a volunteer database. Exclusion criteria included laryngeal disease, previous laryngeal surgery, recent upper respiratory infection, and current smoking. A high-definition videolaryngoscope was used to visualize the larynx. The larynx was topicalised with local anesthetic. Methylene blue was placed on both false vocal cords and at the petiole of the epiglottis. Dye clearance was recorded and analyzed.Results:In total, 10 participants participated, 7 men and 3 women, with a mean age of 42 ± 15.7 years (range: 25-71). The average reflux symptom index score was 1.4. Clearance of the dye from the false vocal cords followed a uniform lateral flow, up onto the aryepiglottic folds. The dye from the petiole had minimal vertical movement. Swallowing cleared dye from the aryepiglottic folds. The average time for dye clearance to the aryepiglottic fold was 2.21 ± 1.14 minutes.Conclusions:This is the first study visualizing the mucociliary clearance of the larynx. Ciliary directionality was consistent in the participants studied, with dye moving superolateral from the false cords to the aryepiglottic fold. Swallowing was an effective mechanism for clearance from the endolarynx, when the dye had reached the aryepiglottic fold. Future research can study potential alterations in laryngeal mucociliary clearance in chronic disease states.
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4

Park, June Dong, Seung Young Lee, Sang-Hoon Cha, Bum Sang Cho, Min Hee Jeon, and Il Hun Bae. "Schwannoma of the Aryepiglottic Folds: A Case Report." Journal of the Korean Society of Radiology 62, no. 1 (2010): 7. http://dx.doi.org/10.3348/jksr.2010.62.1.7.

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5

Kavanagh, Kevin T., and Richard W. Babin. "Endoscopic Surgical Management for Laryngomalacia." Annals of Otology, Rhinology & Laryngology 96, no. 6 (November 1987): 650–53. http://dx.doi.org/10.1177/000348948709600606.

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Laryngomalacia is the most common of the many causes of respiratory stridor in the newborn. It may be identified by fiberoptic nasopharyngoscopy in the nursery or office. Several anatomic mechanisms of supraglottic collapse have been reported in the literature. The most common is a narrowing of the supraglottic airway with blockage of the glottic opening by the redundant tissue of the aryepiglottic folds. Although surgery rarely is indicated, severe airway obstruction, necessitating surgical intervention, can occur. Resection of supraglottic tissue should be performed only as an alternative to tracheotomy. Surgical procedures ranging from tracheotomy to epiglottidectomy have been advocated. Direct visualization of the obstructing tissue by nasopharyngoscopy allows the planning of an appropriate surgical procedure. In a patient with lateral supraglottic collapse, deep resection of the epiglottis would be expected to weaken the support of the aryepiglottic folds and aggravate the airway condition. Similarly, resection of tissue along the aryepiglottic folds will be useful only if preoperative evaluation demonstrates the obstruction to be at this location.
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Seid, Allan B., Sung Min Park, Michael J. Kearns, and Stephen Gugenheim. "Laser division of the aryepiglottic folds for severe laryngomalacia." International Journal of Pediatric Otorhinolaryngology 10, no. 2 (November 1985): 153–58. http://dx.doi.org/10.1016/s0165-5876(85)80027-6.

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7

Sood, S., R. Clarke, A. Bowhay, and S. De. "Manoeuvre to aid Endoscopic division of aryepiglottic folds (Aryepiglottoplasty)." Clinical Otolaryngology 43, no. 3 (September 4, 2017): 981–82. http://dx.doi.org/10.1111/coa.12954.

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8

Martin, Paul A., Christopher A. Church, and George Chonkich. "Schwannoma of the Epiglottis: First Report of a Case." Ear, Nose & Throat Journal 81, no. 9 (September 2002): 662–63. http://dx.doi.org/10.1177/014556130208100916.

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Schwannomas of the larynx are rare. Most of the few such reports in the literature have described schwannomas that occurred in the aryepiglottic fold or the true vocal folds. In this article, we report what we believe is the first case of a schwannoma arising from the epiglottis.
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9

El-Kholy, Noha Ahmed, Menna Ibrahim Hashish, and Ahmed Abdel-Fattah ElSobki. "Coagulation of the lateral surface of aryepiglottic folds as an alternative to aryepiglottic fold release in management of type 2 laryngomalacia." Auris Nasus Larynx 47, no. 3 (June 2020): 443–49. http://dx.doi.org/10.1016/j.anl.2019.10.004.

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10

KC, A., Dipesh Shakya, and A. Nepal. "Laryngeal schwannoma presented as globus sensation." Nepalese Journal of ENT Head and Neck Surgery 5, no. 1 (February 28, 2017): 24–25. http://dx.doi.org/10.3126/njenthns.v5i1.16874.

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Laryngeal Schwannoma is an extremely rare with incidence of 0.1 – 1.5% in all benign laryngeal tumours making it difficult to diagnose. The most common anatomical site is the aryepiglottic fold, followed by the arytenoids, ventricular folds, and vocal cord. Most patients present with hoarseness, dysphagia or globus sensation.The present case report describes a 37 year old female patient with symptoms of globus sensation.
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11

Hamada, Kenta, Akiko Yoshida, and Hiroyuki Okada. "Esophagogastroduodenoscopy-Induced Angina Bullosa Hemorrhagica of the Aryepiglottic Folds and Arytenoid." Clinical Gastroenterology and Hepatology 17, no. 13 (December 2019): A32. http://dx.doi.org/10.1016/j.cgh.2018.08.050.

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12

King, Dana S., Eric Tulleners, Benson B. Martin, Eric J. Parente, and Ray Boston. "Clinical experiences with axial deviation of the aryepiglottic folds in 52 racehorses." Veterinary Surgery 30, no. 2 (April 2001): 151–60. http://dx.doi.org/10.1053/jvet.2001.21389.

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13

Deo, Arju, Daisy Maharjan, and Alina Karna. "Schwannoma of False Vocal Cord - A Rare Entity." Nepal Journal of Health Sciences 1, no. 1 (July 30, 2021): 60–63. http://dx.doi.org/10.3126/njhs.v1i1.38735.

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Laryngeal Schwannoma is rare comprising 0.1 – 1.5% of all benign laryngeal tumors. The most common site in larynx is aryepiglottic fold followed by arytenoids, ventricular folds, and vocal cord. Patients present with the symptoms of hoarseness, dysphagia or globus sensation. We present a 33-year-old male with supraglottic schwannoma who experienced hoarseness of voice for three months. The patient underwent micro laryngeal surgery and submucosal solid tumor of false vocal cord was removed. Postoperative recovery was uneventful and after one month of follow up the patient was improving with no hoarseness of voice.
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14

Pandey, Apoorva K., Tripti Maithani, Arvind Varma, Sharad Gangrade, and Ankur Malhotra. "Computerized Tomographic Assessment of Vocal Cord Palsy: Otolaryngologist's Purview." International Journal of Phonosurgery & Laryngology 6, no. 2 (2016): 57–63. http://dx.doi.org/10.5005/jp-journals-10023-1123.

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ABSTRACT Aims and objectives Vocal cord palsy (VCP) can be definitely depicted on computed tomograpy (CT) scan by identifying key points at the level of true vocal cords and aryepiglottic folds. There are various VCP mimics and imaging shortcomings, and these can usually be circumvented by thoughtfully assessing the scan plan and level, and a diligent search for additional characteristics. Materials and methods This retrospective study consisted of 10 cases of unilateral VCP, who all had been clinically diagnosed of VCP and further evaluated by CT. Pre- and postcontrast enhanced axial CT from skull base to aorto-pulmonary window were done and multiplanar three-dimensional reconstruction of images in coronal and sagittal planes along with volume-rendered imaging was done. Results Most consistent findings in VCP were thickening of ipsilateral aryepiglottic fold and medialization of ipsilateral aryepiglottic fold (100%), followed by dilation of ipsilateral pyriform sinus (90%) and dilatation of ipsilateral laryngeal ventricle (80%). Etiologic causes were ascertained in three cases: Thyroid malignancy, tuberculosis, and pyriform sinus malignancy. The last etiology was probably a VCP mimic. Conclusion Radiologic evaluation is inarguably useful for determining the etiology of VCP, particularly for lesions within neck and thoracic cavity. Most crucial objective in assessing a case of VCP is to exclude the presence of a life-threatening primary lesion as the cause of VCP. How to cite this article Pandey AK, Gangrade S, Malhotra A, Varma A, Maithani T. Computerized Tomographic Assessment of Vocal Cord Palsy: Otolaryngologist's Purview. Int J Phonosurg Laryngol 2016;6(2):57-63.
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15

Nonomura, Naobumi, Satoshi Seki, Masahiro Kawana, Takahiro Okura, and Yuichi Nakano. "Acquired airway obstruction caused by hypertrophic mucosa of the arytenoids and aryepiglottic folds." American Journal of Otolaryngology 17, no. 1 (January 1996): 71–74. http://dx.doi.org/10.1016/s0196-0709(96)90049-6.

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16

Bent, John P., Dee Ann Miller, John W. Kim, Nancy M. Bauman, Jeff S. Wilson, and Richard J. H. Smith. "Pediatric Exercise-Induced Laryngomalacia." Annals of Otology, Rhinology & Laryngology 105, no. 3 (March 1996): 169–75. http://dx.doi.org/10.1177/000348949610500301.

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Laryngomalacia is a well-recognized cause of airway obstruction and inspiratory stridor in infants. As children grow and become more active, laryngomalacia may manifest in different, unexpected ways. Otherwise healthy athletes may generate enough inspiratory force to draw the aryepiglottic folds into the endolarynx, causing a subtotal glottic obstruction. This problem may be overlooked or attributed to asthma, lack of fitness, or functional abnormalities. The purpose of this report is to review the prevalence, diagnosis, and treatment of exercise-induced laryngomalacia (EIL) in children and young adults. To study the incidence and diagnosis of this disorder, we examined 10 healthy volunteers. Fiberoptic laryngoscopy was used to videotape each subject's larynx during active exercise on a stationary bicycle. All volunteers demonstrated altered laryngeal dynamics with exercise, and 1 of the 10 volunteers developed laryngomalacia. Anatomically, it appears that the aryepiglottic fold serves as the critical point of obstruction. When symptomatic, laryngomalacia may be treated with supraglottoplasty. We have had experience with 2 EIL patients in the last 12 months who have undergone carbon dioxide laser microlaryngoscopy with supraglottoplasty. Both patients benefited significantly from surgery. We conclude that EIL is underdiagnosed but responds well to treatment.
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17

Castellanos, Paul F. "Method and Clinical Results of a New Transthyrotomy Closure of the Supraglottic Larynx for the Treatment of Intractable Aspiration." Annals of Otology, Rhinology & Laryngology 106, no. 6 (June 1997): 451–60. http://dx.doi.org/10.1177/000348949710600602.

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A new procedure has been developed to surgically separate the pharynx from the trachea that employs the best features of the Montgomery technique, but restricts the closure to only the epiglottis and the aryepiglottic folds. The petiole of the epiglottis is plicated to the false vocal folds and the interarytenoid mucosa. It is performed entirely through a midline thyrotomy approach and avoids injury to any of the structures within the rima glottidis. It has been successfully performed on seven very ill patients to date. The surgical decision-making process involved, a complete description of the surgical procedure, and a summary of the patients' preoperative condition, workup, and outcomes are presented and discussed.
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18

Nazish, Zahra, Muhammad Inayatullah, and Muhammad Younus Khan. "ETIOLOGY OF DYSPHAGIA." Professional Medical Journal 23, no. 09 (September 10, 2016): 1039–44. http://dx.doi.org/10.29309/tpmj/2016.23.09.1692.

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Objectives: To determine the etiology of dysphagia based on upper GI endoscopyin Nishtar Hospital Multan. Study design: Retrospective study. Place and Duration of study:This study was conducted at gastroenterology unit of Nishtar Hospital Multan from Feb 2013 toAugust 2014. Patients and methods: Three hundred and twenty three patients, ≥ 13 years old,who presented with history of dysphagia to the gastroenterology unit of Nishtar Hospital Multan.Results: Out of 323 patients, 43.7% were males and 56.3% were females. Mean age of patientswas 44.37±17.395 years. Most common finding was benign stricture (28.5% cases) followedby no abnormality (21.7%), carcinoma esophagus (20.7%), achalasia (6.5%), esophagealweb (4%), ulcers (3.7%), multiple pathologies (3.1%), pharyngeal cancer (2.2%), esophagealcandidiasis (1.9%), reflux esophagitis (1.5%) and hiatus hernia (1.2%). Uncommon findingswere incompetent LES (0.9%), extrinsic compression (0.9%), vocal cord paralysis (0.6%),barrett’s esophagus (0.6%), herpes simplex esophagitis (0.6%), shatzki ring (0.3%), diverticulum(0.3%) and thick aryepiglottic folds (0.3%.). Conclusion: Esophagogastroduodenoscopy is theinvestigation of choice for patients of dysphagia. Most common finding in our study was benignstricture in young females, followed by carcinoma esophagus, achalasia, web, ulcer, pharyngealcancer, reflux esophagitis, esophageal candidiasis and hiatus hernia. Incompetent LES,extrinsic compression, vocal cord paralysis, barrett esophagus, herpes simplex esophagitis,ring, diverticulum and thick aryepiglottic folds were rare causes. Measures should be taken toavoid the preventable causes by patient awareness and adequate treatment of predisposingfactors.
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19

Hirano, Minoru, Morio Tateishi, Shigejiro Kurita, and Hidetaka Matsuoka. "Deglutition following Supraglottic Horizontal Laryngectomy." Annals of Otology, Rhinology & Laryngology 96, no. 1 (January 1987): 7–11. http://dx.doi.org/10.1177/000348948709600102.

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In order to determine factors that may contribute to deglutition problems following supraglottic horizontal laryngectomy or its modified techniques, clinical records of 38 patients were studied. Contribution of the following factors was investigated: Age; sex; tumor classification; radical neck dissection; extent of and symmetry in removal of the aryepiglottic folds, arytenoid cartilages, and false folds; removal of the base of the tongue, hyoid bone, and a part of the vocal folds; extent of removal of the epiglottis and thyroid cartilage; cricopharyngeal myotomy; and some complications and concomitant diseases. The results suggest that removal of the arytenoid cartilage and asymmetrical removal of the false folds contribute to deglutition problems. We conclude that the standard supraglottic horizontal laryngectomy associated with surgical approximation of the larynx to the base of the tongue and cricopharyngeal myotomy does not usually cause serious deglutition problems. When the arytenoid cartilage is removed, reconstruction of the structure is required for the prevention of severe aspiration.
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20

Kanaujia, Surendra Kumar, and Annanya Soni. "A Rare Benign Tumor of Vocal Cord: Myxofibrolipoma." International Journal of Phonosurgery & Laryngology 4, no. 2 (2014): 67–68. http://dx.doi.org/10.5005/jp-journals-10023-1086.

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ABSTRACT Laryngeal lipomas are rare. Most of these arise from the aryepiglottic folds of which intrinsic tumors most frequently originate from the false vocal cords. The present case report describes a giant tumor arising from true vocal cord, and that too with a rare histopathology which revealed lipoma with myxomatous degeneration and fibrous changes. Clinical features, management and relevant literature are discussed. How to cite this article Kanaujia SK, Soni A. A Rare Benign Tumor of Vocal Cord: Myxofibrolipoma. Int J Phonosurg Laryngol 2014;4(2):67-68.
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21

Siou, G. S., J. P. Jeannon, and F. W. Stafford. "Acquired idiopathic laryngomalacia treated by laser aryepiglottoplasty." Journal of Laryngology & Otology 116, no. 9 (September 2002): 733–35. http://dx.doi.org/10.1258/002221502760238073.

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Laryngomalacia is the most common paediatric airway problem presenting as stridor in the neonate. This congenital anomaly is thought to be caused by inward inspiratory collapse of the supraglottic larynx due to a prolapsed, tall and tubular epiglottis with flaccid aryepiglottic folds. The natural history of this condition usually results in spontaneous resolution by the second year of life. Although acquired cases of adult laryngomalacia have been reported, a search of the literature has yet to show any cases of idiopathic laryngomalacia. We present two cases of idiopathic acquired laryngomalacia in adults.
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22

Robbins, K. Thomas, Lincoln Gray, and Leslie Michaels. "Statistical Correlations among Supraglottic Cancers." Annals of Otology, Rhinology & Laryngology 97, no. 4 (July 1988): 333–36. http://dx.doi.org/10.1177/000348948809700401.

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The purpose of this study was to quantify the extent to which the presence or absence of cancer in endoscopically evaluable regions of the supraglottic larynx predicted occurrence in a region less easy to visualize but of critical importance to the nature of treatment. Histologic findings from 32 specimens were subjected to two separate statistical analyses. In the first analysis, the presence of cancer on the floor of the ventricle was the best predictor of tumor below this level. The combination of variables with the best correlation was cancer on the floor of the ventricle and in the vestibular folds. In the second analysis, involvements of the deep structures in the aryepiglottic folds and in the infrahyoid epiglottis were the only significant predictors of tumor extending to the preepiglottic space. The results suggest that such statistical analyses may provide guidelines for selection of treatment.
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23

Amin, Milan R., and Glenn Isaacson. "State-Dependent Laryngomalacia." Annals of Otology, Rhinology & Laryngology 106, no. 11 (November 1997): 887–90. http://dx.doi.org/10.1177/000348949710601101.

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We have observed 5 infants who demonstrate normal breathing when awake, but develop stridor while asleep. Flexible laryngoscopy in the awake state reveals either a normal larynx or redundancy of the aryepiglottic folds or arytenoid soft tissue without prolapse into the laryngeal inlet. When these children are sedated, however, the classic signs of laryngomalacia appear. Wet inspiratory stridor with concomitant supraglottic prolapse can be demonstrated by flexible videolaryngoscopy in this state. As these findings vary with level of consciousness, we have dubbed this condition “state-dependent” laryngomalacia. We believe the appearance and disappearance of classic laryngomalacia with changes in level of consciousness adds credence to the neurogenic theory of laryngomalacia.
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24

Grobman, Ariel B., Richard J. Vivero, German Campuzano-Zuluaga, Parvin Ganjei-Azar, and David E. Rosow. "Laryngeal Involvement of Multiple Myeloma." Case Reports in Oncological Medicine 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/257814.

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The objectives of this paper are to discuss a rare cause of laryngeal multiple myeloma, to review unique pathologic findings associated with plasma cell neoplasms, to discuss epidemiology, differential diagnosis, and treatment options for plasma cell neoplasms of the larynx. Laryngeal multiple myeloma, also noted in the literature as “metastatic” multiple myeloma, presenting as a de novo laryngeal mass is extremely rare with few reported cases. Laryngeal involvement of extramedullary tumors is reported to be between 6% and 18% with the epiglottis, glottis, false vocal folds, aryepiglottic folds, and subglottis involved in decreasing the order of frequency. We present the case of a 58-year-old male with a history of IgA smoldering myeloma who presented to a tertiary care laryngological practice with a two-month history of dysphonia, which was found to be laryngeal involvement of multiple myeloma. We review the classification of and differentiation between different plasma cell neoplasms, disease workups, pathologic findings, and treatment options.
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25

Zalzal, George H., Jack B. Anon, and Robin T. Cotton. "Epiglottoplasty for the Treatment of Laryngomalacia." Annals of Otology, Rhinology & Laryngology 96, no. 1 (January 1987): 72–76. http://dx.doi.org/10.1177/000348948709600118.

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Laryngomalacia is the most common congenital laryngeal anomaly. Patients present with different degrees of stridor and feeding problems that usually resolve by 18 months of age. A small number present with severe feeding problems, failure to thrive, stridor with cyanosis, and apnea, which may result in cardiopulmonary disease. These infants require surgical intervention, usually a hyomandibulopexy or tracheotomy. We present a new procedure, epiglottoplasty, that is performed endoscopically and involves excision of redundant mucosa over the lateral edges of the epiglottis, aryepiglottic folds, arytenoids, and corniculate cartilages. Ten patients have undergone this procedure with good results. Epiglottoplasty represents an alternative to tracheotomy in severe laryngomalacia. Indications, techniques, postoperative management, and complications are presented.
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26

Esling, John H. "The Articulatory Function of the Larynx and the Origins of Speech." Annual Meeting of the Berkeley Linguistics Society 38 (September 25, 2012): 121. http://dx.doi.org/10.3765/bls.v38i0.3325.

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<p>The ‘laryngeal articulator,’ consisting of the glottal mechanism, the supraglottic tube, the pharyngeal/epiglottal mechanism, and including three levels of folds: the vocal folds, the ventricular folds, and the aryepiglottic folds, is shown to be responsible for the generation of multiple source vibrations and for the complex modification of the pharyngeal resonating chamber that accounts for a wide range of contrastive auditory qualities. These qualities are observed in a surprisingly large number of the languages of the world, both linguistically and paralinguistically, and they account for sounds which have been labeled as ‘pharyngeal,’ as ‘epiglottal,’ and as various phonation types. They reflect an expanding range of what have been known as the ‘states of the glottis’ and which may be more properly termed ‘states of the larynx.’ It has also been observed that infants, in their first months of life, produce a range of qualities, reflecting both phonatory possibilities and stricture types, that can also be attributed to the laryngeal articulator mechanism. Systematic observation of infants’ early speech production reveals that the control of articulatory detail in the pharynx is mastered during the first year of life. Understanding and control of manner of articulation in the pharynx appears to be a prerequisite for expanding articulatory control into the oral vocal tract. Taking the pharynx as a starting point for the ontogenetic learning of the speech production capacity offers fruitful insights into the phylogenetic development of speech.</p>
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Yelken, K., M. Guven, M. Topak, E. Gultekin, and F. Turan. "Effects of antituberculosis treatment on self assessment, perceptual analysis and acoustic analysis of voice quality in laryngeal tuberculosis patients." Journal of Laryngology & Otology 122, no. 4 (April 2008): 378–82. http://dx.doi.org/10.1017/s0022215107008961.

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AbstractObjectives:To evaluate the effects of antituberculosis treatment on the voice quality of laryngeal tuberculosis patients, measured by patient self-assessment, perceptual analysis and acoustic analysis.Materials and methods:A total of 14 laryngeal tuberculosis patients were enrolled. Laryngeal tuberculosis was established either by biopsy and histopathological examination or by rapid regression of the laryngeal lesions after antituberculosis medication. Before and after treatment, all patients were evaluated perceptually (on a scale of zero to three), and 12 assessed their own voices using the voice handicap index-10 scale. Acoustic analysis was performed to allow objective evaluation.Results:Patients' ages ranged from 21 to 72 years (mean, 41). The male to female ratio was 12:2. Eight patients (57 per cent) had tuberculous involvement of the epiglottis, four (28 per cent) had involvement of the aryepiglottic fold and eight (57 per cent) had involvement of the false vocal folds. The glottis was the less commonly involved part of the larynx, including true vocal folds (28 per cent, n = 4) and posterior commissure (14 per cent, n = 2). Perceptual evaluation, on a scale of zero to three, gave the patients a median score of six; after commencement of treatment, the median score decreased to two. The mean voice handicap index-10 score decreased from 24 to 12 after treatment. An obvious improvement in acoustic analytical parameters was also found following treatment.Conclusions:Antituberculosis treatment clearly improved the voice outcomes of laryngeal tuberculosis patients, according to self-assessment, perceptual analysis and acoustic analysis.
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28

Dalrymple, Alice, John D. Gilbert, and Roger W. Byard. "Delayed fatal upper-airway obstruction due to laryngopharyngeal burns and thermal epiglottis." Medicine, Science and the Law 60, no. 3 (May 9, 2020): 223–26. http://dx.doi.org/10.1177/0025802420918040.

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A 48-year-old man complained of throat swelling and difficulty swallowing after eating hot food. Several hours later, he collapsed and was observed to be gasping for breath. Bystander and ambulance-initiated cardiopulmonary resuscitation was unsuccessful, and he was pronounced deceased at the scene. At autopsy, the aryepiglottic folds were markedly oedematous, with adjacent areas of mucosal inflammation and necrosis from a recent burn. Death was attributed to upper-airway obstruction due to glottic inlet oedema associated with epiglottic and laryngopharyngeal thermal injury. Although thermal epiglottitis not involving fire is an unusual injury and is rarely fatal, the reported case demonstrates a lethal episode arising from the ingestion of excessively hot food. Thermal epiglottitis therefore represents an uncommon cause of delayed upper-airway obstruction in adults that should be considered in individuals presenting with a sore throat and shortness of breath, particularly if there is a history of hot-food ingestion.
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29

Jayendiran, S. "A RARE CASE OF NEUROFIBROMATOSIS WITH SQUAMOUS CELL CARCINOMA OF EPIGLOTTIS." UP STATE JOURNAL OF OTOLARYNGOLOGY AND HEAD AND NECK SURGERY VOLUME 9, ISSUE 1 (June 15, 2021): 40–42. http://dx.doi.org/10.36611/upjohns/volume9/issue1/10.

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INTRODUCTION: The neurofibroma is a nonmalignant new growth of neuroectodermal origin. neurofibromas appear at the end of a nerve, often in the skin, producing small nonencapsulated nodules which may have pigmentation in the overlying skin. Neurofibromatosis with laryngeal involvement presents with dyspnea, followed by hoarseness, stridor, dysphagia, and voice change. most common sites involved in the larynx are the arytenoids and the aryepiglottic folds. CASE REPORT: 65-year-old female with previously diagnosed of neurofibromatosis since 10 years of age manifested by multiple cutaneous nodules The patient had symptoms of dysphagia, hoarseness of voice for past 2 months. Direct laryngeal examination using flexible endoscope showed a edematousulceroproliferative growth in the laryngeal surface of epiglottis and fullness in the left pyriform fossa. Hisopathological examination revealed squamous cell carcinoma from epiglottis and fibromatosis changes from pyriform fossa. CONCLUSION: All neurofibromatosis patient and their family members should under go regular oral and laryngeal examination to rule out complications at the earliest.
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Ma, Yue, Matthew R. Naunheim, Jill Gregory, and Peak Woo. "Transoral Tubed Supraglottoplasty: A New Minimally Invasive Procedure for Aspiration." Annals of Otology, Rhinology & Laryngology 128, no. 12 (July 17, 2019): 1122–28. http://dx.doi.org/10.1177/0003489419862581.

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Objectives: We describe a new procedure for aspiration called tubed supraglottoplasty (TS). TS is a transoral procedure that approximates the aryepiglottic (AE) folds and arytenoids. This narrows the laryngeal inlet. This procedure has been used to improve swallowing and reduce aspiration in patients with vocal fold paralysis. We describe the technical aspects of TS and report on 11 patients. Methods: TS is done by oral intubation followed by suspension laryngoscopy. An incision is made along the AE fold into the posterior commissure and then continued to the opposite AE fold. Dissection within this incision creates two mucosal flaps, one based on the laryngeal surface and the other on the pharyngeal surface. Two 1-cm releasing incisions are made at each end of the AE fold. The laryngeal mucosal flap is approximated using a 3-0 self-locking running suture. The pharyngeal mucosal flap is approximated as a second layer. This double-layered mucosal V-Y advancement flap builds up the posterior laryngeal height. It narrows and “tubes” the supraglottis. Results: All patients tolerated TS without airway complications. Ten of the 11 patients reported improved swallowing function with less aspiration. Six of the 8 patients with prior G-tubes had their gastrostomy tube removed. Postoperative laryngoscopy showed a narrowed “tubed” supraglottis with a higher posterior wall preventing spillover and aspiration. An improved Functional Oral Intake Scale was recorded in ten of eleven patients. Conclusion: TS is a minimally invasive procedure that can improve swallowing and reduce aspiration.
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Pouderoux, P., J. A. Logemann, and P. J. Kahrilas. "Pharyngeal swallowing elicited by fluid infusion: role of volition and vallecular containment." American Journal of Physiology-Gastrointestinal and Liver Physiology 270, no. 2 (February 1, 1996): G347—G354. http://dx.doi.org/10.1152/ajpgi.1996.270.2.g347.

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Nonalimentary swallows minimize aspiration by clearing accumulated fluid from the pharynx. This study aimed to define 1) the pharyngeal sensory field to elicit swallowing and 2) the effect of infusion rate, volition, taste, and temperature on pharyngeal swallows. Test solutions were directed into the valleculae at 6.5, 11.5, and 32 ml/min through a catheter in eight healthy volunteers. Deglutition was signaled with electromyography and electroglottography. Spatial distribution of infusate before swallowing was studied using videofluoroscopy coupled with a video timer. Volitional control was assessed with rapid or restrained swallows. Pharyngeal swallow latency decreased as the instillation rate increased, was potently modified with volition, and was unchanged by infusate taste or temperature. Water infusion into the valleculae did not trigger pharyngeal swallowing until liquids overflowed and reached the aryepiglottic folds or pyriform sinuses. The variation in swallow latency among flow rates was mainly due to the duration of liquid containment within the valleculae. This suggests that the valleculae act to contain pharyngeal secretions and residue and prevent aspiration by diverting their contents around the larynx before swallowing.
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Martin, J. E., K. E. Howarth, I. Khodaei, A. Karkanevatos, and R. W. Clarke. "Aryepiglottoplasty for laryngomalacia: the Alder Hey experience." Journal of Laryngology & Otology 119, no. 12 (December 2005): 958–60. http://dx.doi.org/10.1258/002221505775010904.

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Laryngomalacia is the most common cause of stridor in infants. Severely affected children are at risk of feeding difficulties, apnoeic episodes and cor pulmonale secondary to upper airway obstruction. The aim of this study was to assess the outcome of aryepiglottoplasty. This is a simple surgical procedure that relieves the obstruction by dividing the aryepiglottic folds. Thirty children had an aryepiglottoplasty at the Royal Liverpool Children’s Hospital between January 1995 and June 2001. The case notes of all 30 children were reviewed for age, sex, age at operation, indications, operative technique, complications and long-term outcomes. Complete resolution of stridor was obtained in 83 per cent of patients, with an improvement in a further 7 per cent. Post-operative complications included lower respiratory tract infections (13 per cent) and vomiting (7 per cent). In conclusion, simple endoscopic aryepiglottoplasty remains an effective way of treating upper airway obstruction in children. Its high resolution and low complication rate make it a safe, first choice procedure for treatment of moderate to severe laryngomalacia.
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Petrovic, Zeljko. "Results of supraglottic partial horizontal laryngectomies." Medical review 56, no. 11-12 (2003): 568–70. http://dx.doi.org/10.2298/mpns0312568p.

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Introduction Supraglottis is a part of larynx comprising two sub regions: epilarynx (suprahyoid epiglottis - including lingual and laryngeal surface, aryepiglottic folds - laryngeal surface, and arytenoids) and supraglottis without epilarynx (infrahyioid epiglottis and ventricular folds). Material and methods A total of 234 patients with supraglottic squamous cell carcinoma undergoing primary surgery were analyzed in the period 1976-1996. The tumor was localized in epilarynx in 84 (25%) patients, and in supraglottis without epilarynx in 261 (75%) cases. Results T1 tumor was present in 145 (42%) patients, T2 tumor was found in 178 (52%) patients, while T3 was reported in 22 (6%) cases. Clinically negative neck (N0) was found in 290 (84%) patients, and palpable metastases (N1) manifested in 55 (16%) cases. Local recurrences were established in 18 (5%) patients, and subsequent postoperative cervical metastases were found in 45 (13%) cases. Five-year disease-free survival was reported in all patients approximately 12 days following surgery. 27 patients developed laryngeal stenosis and only 2 patients were not decanulated. Voice and speech functions were satisfactory. Discussion Supraglottic laryngectomy, extended supraglottic laryngectomy is fully justified from oncological and functional aspects. Selective neck dissection in N0 cervical findings provides detection of occult metastases and indicates need for postoperative radiotherapy. Conclusion Oncological and functional results of supraglottic laryngeal surgery, along with simultaneous treatment of neck by selective, modified radical neck dissection and postoperative radiotherapy offer hope for treatment of supraglottic laryngeal cancer.
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Srikanth, N., Feroz B. Shaik, and KVS Kumar Chowdary. "A Clinical Study of Laryngeal Cysts." International Journal of Phonosurgery & Laryngology 6, no. 2 (2016): 53–56. http://dx.doi.org/10.5005/jp-journals-10023-1122.

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ABSTRACT Aim To study cases of cysts of larynx and review the literature regarding precipitating factors and methods of treatment. Materials and methods A retrospective study of eight cases of cysts of larynx in our hospital was carried out from July 2012 to December 2015. In all cases, diagnosis was made by video laryngoscopy and was treated by microlaryngeal surgery under general anesthesia (GA). Results Eight patients with laryngeal cysts were identified, of which five were male and three were female. The mean age was ranging from 40 to 60. On examination, two were diagnosed with cysts from epiglottis, three from aryepiglottic folds, two from false vocal cords, and one from the ventricle. Conclusion As saccular cysts are identified to be associated with neoplastic transformation, it is important to recognize the laryngeal saccular cyst and manage appropriately in its early stages and to differentiate it from other laryngeal cysts. Thorough diagnostic evaluation and surgical intervention necessitates the appropriate management. How to cite this article Kumar Chowdary KVS, Srikanth N, Shaik FB. A Clinical Study of Laryngeal Cysts. Int J Phonosurg Laryngol 2016;6(2):53-56.
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Lee, Shiann-Yann, Ching-Ting Tan, Te-Huei Yeh, Mao-Chang Su, Pei-Jen Lou, and William W. Montgomery. "Mucociliary Transport Pathway on Laryngotracheal Tract and Stented Glottis in Guinea Pigs." Annals of Otology, Rhinology & Laryngology 109, no. 2 (February 2000): 210–15. http://dx.doi.org/10.1177/000348940010900217.

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We investigated the laryngotracheal mucociliary transport pathway of guinea pigs in vivo and immediately postmortem. Only intraperitoneal anesthesia was used during the procedure to avoid the disturbance of mucociliary function. Resin particles were used as the marking substance. A microcolpohysteroscope was placed at different levels in the laryngotracheal region for observing the marking particles and recording the transport pattern. The tracheal mucociliary transport flow primarily moved along the posterior wall and both lateral walls in a zigzag trace. Upon reaching the subglottis, the resin particles stayed underneath the vocal cords, and a whirlpool phenomenon developed. The majority of the particles were shifted and directed onto the posterior glottic area. With a short delay, some resin particles crossed over the free edge of the vocal cords and turned posteriorly along the medial upper cordal margin. No mucociliary transport could be observed on the entire upper surface of the true vocal cords, which is covered by squamous epithelium. Occasionally, a few resin particles in the vicinity of the epiglottic root traveled along the aryepiglottic folds toward the posterior commissure. All streams of mucociliary transport finally joined together in the interarytenoid area. After leaving the glottis, the resin particles traveled to the hypopharynx and entered the esophagus through the motion of deglutition. The pattern of mucociliary clearance in the laryngotracheal region was not delayed by stenting.
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PERON, DIDIER L., DONATELLA B. GRAFFINO, and DAVID O. ZENKER. "THE REDUNDANT ARYEPIGLOTTIC FOLD." Laryngoscope 98, no. 6 (June 1988): 659???663. http://dx.doi.org/10.1288/00005537-198806000-00016.

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Koskinen, Milja J., Anna‐Maija K. Virtala, and Turlough McNally. "Racing performance of National Hunt thoroughbred racehorses after treatment of palatal dysfunction with a laryngeal tie‐forward procedure and thermocautery of the soft palate with or without aryepiglottic folds resection." Veterinary Surgery 49, no. 1 (September 10, 2019): 114–23. http://dx.doi.org/10.1111/vsu.13321.

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Clark, Christine M., Dale S. DiSalvo, Jansie Prozesky, and Michele M. Carr. "Sleep Disordered Breathing May Signal Laryngomalacia." Open Anesthesiology Journal 11, no. 1 (August 21, 2017): 68–74. http://dx.doi.org/10.2174/1874321801711010068.

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Background: Pediatric anesthesiologists are often confronted with children with sleep-disordered breathing (SDB) presenting for tonsillectomy and/or anesthesia. The typical patient has symptoms of obstructive sleep apnea (OSA) with enlarged tonsils; however, a subset of patients may have underlying laryngomalacia (LM) without tonsillar hypertrophy. Both OSA and LM significantly increase the risk of intra- and postoperative airway obstruction and sensitivity to narcotics. The prevalence of LM may be underestimated, because direct laryngoscopy (DL) is not routinely performed in the diagnostic evaluation of patients with SDB who lack tonsillar hypertrophy. Aim: To identify the prevalence and DL findings in pediatric patients with SDB without tonsillar hypertrophy. Methods: Retrospective chart review of 108 patients with SDB who underwent general anesthesia for adenotonsillectomy (TA) or adenoidectomy with concomitant DL. The following data were collected: demographic information, medical comorbidities, polysomnography results, anesthetic techniques, and postoperative complications. Results: 94.5% of children had DL findings consistent with LM, including a retropositioned epiglottis and short aryepiglottic folds. Postglottic edema was observed in 42.2%, and these patients were significantly more likely to have a diagnosis of gastroesophageal reflux (P=0.023). 57.8% had vocal cord edema. 75.3% of children who received routine postoperative follow-up care experienced complete symptom resolution. Postoperative complications following discharge from hospital occurred in 12.4% of patients, and 15.7% underwent supraglottoplasty for continued SDB symptoms after TA or adenoidectomy. Conclusion: A substantial proportion of patients with SDB who lacked tonsillar hypertrophy had findings consistent with LM, suggesting that the larynx may be the primary site of upper airway obstruction in these patients. This has significant implications in terms of perioperative management. The majority of patients with SDB had symptomatic improvement following TA or adenoidectomy; however, a subset required further surgical intervention with supraglottoplasty.
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Uraskulova, B. B., and A. O. Gyusan. "Case report of extensive foreign body of esophagus with spread to laryngopharynx and larynx." Russian Otorhinolaryngology 20, no. 4 (2021): 79–82. http://dx.doi.org/10.18692/1810-4800-2021-4-79-82.

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Foreign bodies of the respiratory tract and esophagus remain one of the pressing problems in medicine, which is associated with the possibility of developing complications that can end in death. We present our clinical observation that demonstrates the long-term presence of a large foreign body fixed in the area of the pharyngeal narrowing of the esophagus and extending into the larynx and the vestibule of the larynx. Patient T., 57 years old, went to the emergency department of the Karachay-Cherkessia Republican Clinical Hospital with complaints of severe sore throat, inability to swallow, excessive salivation, increased body temperature to 37,5 °C, difficulty breathing, mixed shortness of breath, which persist for 3 days. The examination revealed: the epiglottis is mobile, the mucous membrane of the larynx is hyperemic, edematous, with an abundance of saliva, at the level of the vestibular part of the larynx, in the area of the arytenoid cartilage and aryepiglottic folds, an irregular shape was visualized, with smooth edges, a thin, hard whitish plate. Computed tomography of the cervical spine: in the esophagus, at the level of C4-C5 vertebrae, a foreign body with a metallic density of +2900 hU units, elongated, irregular shape, measuring 2.2 by 3.3 cm, with perifocal air bubbles is determined. A preliminary diagnosis was made: Foreign body of the esophagus, laryngopharynx with a spread to the vestibule of the larynx. 3 days after the retention of the foreign body under intubation anesthesia, it is captured using forceps with serrated cups and removed during direct laryngoscopy. There were no complications during the manipulation. The combination of X-ray and endoscopic examinations with the help of innovative medical and diagnostic equipment made it possible to establish a diagnosis in a short time, choose the most effective treatment tactics and remove a foreign body through natural pathways.
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Chhabra, S., R. Sen, P. Parmar, P. Gupta, A. Sharma, and H. Yadav. "Primary malignant melanoma of aryepiglottic fold." Ghana Medical Journal 49, no. 4 (March 2, 2016): 278. http://dx.doi.org/10.4314/gmj.v49i4.10.

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41

Kim, Dongwon, Ji-Hwan Park, Jae-wook Kim, Soo-Geun Wang, and Wonjae Cha. "Giant fibrovascular polyp on aryepiglottic fold." Auris Nasus Larynx 43, no. 2 (April 2016): 212–15. http://dx.doi.org/10.1016/j.anl.2015.08.004.

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42

Ruari Greer, J., Sharon P. Smith, and Tim Strang. "A Comparison of Tracheal Tube Tip Designs on the Passage of an Endotracheal Tube during Oral Fiberoptic Intubation." Anesthesiology 94, no. 5 (May 1, 2001): 729–31. http://dx.doi.org/10.1097/00000542-200105000-00007.

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Background The design of an endotracheal tube has been shown to influence the passage of the tube through the glottis during fiberoptic intubation. Difficulty in passing the endotracheal tube can occur if the aryepiglottic folds obstruct the passage of the bevel. The relevant aspects of endotracheal tube design include the shape of the bevel, the material used by the manufacturer, and the ability of the tube to conform to the shape of the fiberscope. The aim of the current study was to compare the ease of passage through the glottis of two different tubes. One tube was a wire reinforced polyvinyl chloride tube with a standard bevel and the other was a newly designed tube with a bevel of different shape and made of silicone rubber. The new design is for use with the a commerical intubating laryngeal mask. Methods The authors studied a population of 30 patients who received a standard anesthetic. In all cases, oral fiberoptic intubation was attempted. Anesthetic was administered to each patient using both tubes, and before the study the order of the tubes was randomized. The difficulty in passing the tube was assessed by a blinded observer and graded using a three-point scale (grade 1: no difficulty passing the tube; grade 2: obstruction to passing the tube relieved by withdrawal and a 90 degrees anticlockwise rotation; grade 3: obstruction necessitating more than one manipulation or external laryngeal manipulation). Results In 27 patients, no difficulty was shown by use of the silicone-tipped tube. In only three patients was there difficulty that necessitated a 90 degrees anticlockwise twist. With the wire-reinforced tube, no difficulty was experienced on 14 occasions. Grade 1 difficulty was experienced eight times and difficulty necessitating more than one maneuver, head movement, or external laryngeal manipulation was seen on eight occasions. Statistical significance was achieved at P = 0.0002 (Wilcoxon signed rank test). Conclusions The authors conclude that the use of the silicone-tipped tube with the new bevel design may provide an advantage in the clinical situation of fiberoptic intubation.
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Reidenbach, Martina Maria. "Aryepiglottic fold: Normal topography and clinical implications." Clinical Anatomy 11, no. 4 (1998): 223–35. http://dx.doi.org/10.1002/(sici)1098-2353(1998)11:4<223::aid-ca1>3.0.co;2-s.

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44

Picciotti, P. M., S. Agostino, S. Galla, G. Della Marca, and E. Scarano. "Aryepiglottic fold cyst causing obstructive sleep apnea syndrome." Sleep Medicine 7, no. 4 (June 2006): 389. http://dx.doi.org/10.1016/j.sleep.2006.01.012.

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45

Hong, Chang Eui, Jun Cheol Park, Mi-Kyung Lee, and Hyang Ae Shin. "A Case of Pedunculated Schwannoma of Aryepiglottic fold." Korean Society for Head and Neck Oncology 33, no. 2 (November 30, 2017): 95–99. http://dx.doi.org/10.21593/kjhno/2017.33.2.95.

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46

Polonovski, Jean-Michel, Philippe Contencin, Martine Francois, Paul Viala, and Philippe Narcy. "Aryepiglottic Fold Excision for the Treatment of Severe Laryngomalacia." Annals of Otology, Rhinology & Laryngology 99, no. 8 (August 1990): 625–27. http://dx.doi.org/10.1177/000348949009900807.

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47

Server, Ela A., Yusuf M. Durna, Ozgur Yigit, and Erol R. Bozkurt. "Supraglottic Kaposi’s Sarcoma in HIV-Negative Patients: Case Report and Literature Review." Case Reports in Otolaryngology 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/1818304.

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This paper presents a case report of an HIV-negative, supraglottic Kaposi’s sarcoma patient. The 80-year-old male patient was admitted with complaints of hoarseness, difficulty in swallowing, and a stinging sensation in his throat for approximately six months. The endoscopic larynx examination revealed a lesion which had completely infiltrated the epiglottis, reached right aryepiglottic fold, was vegetating, pink and purple in color, multilobular, fragile, and shaped like a bunch of grapes, and partially blocked the bleeding airway passage. The case was discussed by the hospital’s head-neck cancer committee and a surgery decision was made. A tracheotomy was performed under local anesthesia before the operation due to respiratory distress and endotracheal intubation difficulty. Direct laryngoscopy showed that the mass was limited in the supraglottic area, had invaded the entire left aryepiglottic fold and one-third of the front right aryepiglottic fold, and completely covered epiglottis. It should be remembered that although rare, Kaposi’s sarcoma may be encountered in larynx malignancy cases. Disease-free survival may be achieved through local excision and postoperative radiotherapy.
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Kimura, Miwako, and Roger W. Chan. "Viscoelastic properties of human aryepiglottic fold and ventricular fold tissues at phonatory frequencies." Laryngoscope 128, no. 8 (December 15, 2017): E297—E302. http://dx.doi.org/10.1002/lary.27049.

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49

Fefar, Alpesh D., Paresh J. Khavdu, Mukesh N. Dodia, Sejal N. Mistry, and Manish R. Mehta. "Epitheloid hemangio-endothelioma of right aryepiglottic fold: a rare case report with review of literature." International Journal of Otorhinolaryngology and Head and Neck Surgery 1, no. 2 (October 4, 2015): 93. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20150908.

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<p class="abstract"><span lang="EN-US">Epitheloid hemangio-endothelioma is a very rare tumour of intermittent malignancy of vascular origin, having a tendency to recur with rare incidence of metastasis. The tumour is intermediate between haemangioma and angiosarcoma, mainly affecting liver, lung as well as bones, skin, penis, ovary, scalp, or any part of the body. Internet search was made with the key words epitheloid hemangio-endothelioma and epitheloid hemangio-endothelioma of Larynx, since now only single case has been reported from larynx involving subglottis. Hence we report this rare entity with involvement of the larynx (Sub site: Rt. Aryepiglottic fold) describing clinical and histopathological characteristic. This is perhaps the first case of epitheloid hemangio-endothelioma involving aryepiglottic fold.</span></p>
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Satish, Hosaagrahara Subbegowda, Niveditha Jayanna, Borlingegowda Viswanatha, and Ramabhadraiah Anil Kumar. "Aryepiglottic Fold as a Rare Location for a Monomorphic Adenoma—Case Report." International Journal of Otolaryngology and Head & Neck Surgery 02, no. 02 (2013): 61–62. http://dx.doi.org/10.4236/ijohns.2013.22015.

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