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Journal articles on the topic 'Arylalkyl'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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1

Rzadkowska, Marzena, Elzbieta Szacon, and Maria Zun. "Synthesis of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)- -2,4,5(9H)trioxo-7,8-dihydroimidazo[1,2-a][1,3,5]triazepine." Current Issues in Pharmacy and Medical Sciences 27, no. 1 (2014): 8–9. http://dx.doi.org/10.2478/cipms-2014-0002.

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Abstract A series of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)-2,4,5(9H)trioxo-7,8- dihydroimidazo [1,2-a][1,3,5] triazepine was obtained by condensation of 1-[1-(2-pyridyl) imidazolidine-2-ylidene]-3-aryl(arylalkyl)ureas) with diethyl oxalic acid ester. Considering the structure of the obtained compounds, it can be expected that these compounds can reveal pharmacological activity.
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2

Liu, Ming-Qing, Tao Jiang, Wen-Wen Chen, and Ming-Hua Xu. "Highly enantioselective Rh/chiral sulfur-olefin-catalyzed arylation of alkyl-substituted non-benzofused cyclic N-sulfonyl ketimines." Organic Chemistry Frontiers 4, no. 11 (2017): 2159–62. http://dx.doi.org/10.1039/c7qo00555e.

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3

Wang, Zheng, Jinjin Ye, Rui Wu, et al. "Bi-aryl rotation in phenyl-dihydroimidazoquinoline catalysts for kinetic resolution of arylalkyl carbinols." Catal. Sci. Technol. 4, no. 7 (2014): 1909–13. http://dx.doi.org/10.1039/c3cy00904a.

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Chiral nucleophilic catalysts, 6-aryl-phenyl-dihydroimidazoquinolines (PIQs), were designed, synthesised and applied to the kinetic resolution of arylalkyl carbinols with very high selectivity (S) factors (up to 530).
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4

Abidin, Mohammad Z., Thangavelu Saravanan, Laura Bothof, Pieter G. Tepper, Andy-Mark W. H. Thunnissen, and Gerrit J. Poelarends. "Biocatalytic enantioselective hydroaminations enabling synthesis of N-arylalkyl-substituted l-aspartic acids." Organic & Biomolecular Chemistry 19, no. 29 (2021): 6407–11. http://dx.doi.org/10.1039/d1ob00748c.

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EDDS lyase has a broad substrate scope, accepting diverse arylalkylamines in the enantioselective hydroamination of fumarate enabling the facile synthesis of difficult N-arylalkyl-substituted l-aspartic acids with excellent optical purity.
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5

AQUINO, M., S. CARDANI, G. FRONZA, C. FUGANTI, R. P. FERNANDEZ та A. TAGLIANI. "ChemInform Abstract: Baker′s Yeast Reduction of Arylalkyl and Arylalkenyl γ- and . delta.-Keto Acids." ChemInform 23, № 2 (2010): no. http://dx.doi.org/10.1002/chin.199202079.

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6

Zhigang, Xu, Zhao Yu, Yuan Bing, Qiao Weihong, Li Zongshi, and Cheng Lubo. "Synthesis of Novel Arylalkyl Sulfonate Surfactants." Tenside Surfactants Detergents 41, no. 1 (2004): 31–33. http://dx.doi.org/10.3139/113.100206.

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7

Azzena, Ugo, Simonetta Carta, Giovanni Melloni, and Alessandra Sechi. "Reductive lithiation of arylalkyl methyl ethers." Tetrahedron 53, no. 47 (1997): 16205–12. http://dx.doi.org/10.1016/s0040-4020(97)10080-1.

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8

deSolms, S. Jane, Elizabeth A. Giuliani, Samuel L. Graham, et al. "N-Arylalkyl Pseudopeptide Inhibitors of Farnesyltransferase." Journal of Medicinal Chemistry 41, no. 14 (1998): 2651–56. http://dx.doi.org/10.1021/jm9800907.

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9

Watanabe, S., Y. Igarashi, and K. Yagami. "Antimicrobial activity of someN-(arylalkyl)maleimides." Pesticide Science 34, no. 2 (1992): 99–104. http://dx.doi.org/10.1002/ps.2780340202.

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10

Kniphorst, L. C. E. "The nitration of symmetrical arylalkyl-ureas." Recueil des Travaux Chimiques des Pays-Bas 44, no. 8 (2010): 693–727. http://dx.doi.org/10.1002/recl.19250440806.

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11

Pashkovsky, F. S., Yu S. Dontsu, D. I. Korneev, D. B. Rubinov та F. A. Lakhvich. "One-pot synthesis of cyclic β-dicarbonyl compounds as synthons for 11-deoxyprostanoids". Doklady of the National Academy of Sciences of Belarus 64, № 2 (2020): 186–92. http://dx.doi.org/10.29235/1561-8323-2020-64-2-186-192.

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One-pot synthesis of cyclic β-dicarbonyl synthons for 11-deoxyprostanoids has been developed on the basis of cyclopentane-1,3-dione and 5-phenyl tetronic acid. The obtained 2-alkyl(arylalkyl)-substituted cyclopentane-1,3-diones have been transformed into cyclopentenone precursors of 11-deoxy-PGE 1 and 11-deoxy-PGE 2 analogues.
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12

Dennison, Philip R., Alan Gibson, Alexander I. Gray, and Graham L. Patrick. "Cyclisation studies of 5-arylalkyl-1,2,3,4,5,6,7,8-octahydroisoquinolines." Journal of the Chemical Society, Perkin Transactions 1, no. 5 (1997): 721–28. http://dx.doi.org/10.1039/a605296g.

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13

Itoh, Yoshihiro, Masamitsu Inoue, Akira Hachimori, and Koji Abe. "Alternating Copolymers Consisting of Arylalkyl Methacrylates III: Phosphorescence of Poly(arylalkyl methacrylate-alt-styrene) in a Rigid Solution." Polymers for Advanced Technologies 8, no. 1 (1997): 35–38. http://dx.doi.org/10.1002/(sici)1099-1581(199701)8:1<35::aid-pat608>3.0.co;2-m.

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14

Itoh, Yoshihiro, Masamitsu Inoue, Tomoko Takahashi, Akira Hachimori, and Satoshi Suzuki. "Alternating copolymers consisting of arylalkyl methacrylates. I. Fluorescence properties of poly(arylalkyl methacrylate-alt-styrene) in organic solution." Journal of Polymer Science Part A: Polymer Chemistry 33, no. 7 (1995): 1069–74. http://dx.doi.org/10.1002/pola.1995.080330709.

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15

Gevondian, A. G., Y. N. Kotovshchikov, G. V. Latyshev, N. V. Lukashev, and I. P. Beletskaya. "Metal-free reductive c-c-coupling between arylboronic acids and 2-(5-iodo-1,2,3-triazolyl)phenols." Журнал органической химии 59, no. 9 (2023): 1121–30. http://dx.doi.org/10.31857/s0514749223090021.

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A novel approach to 2-(1-arylalkyl)benzoxazoles via a reaction of arylboronic acids with 2-(5-iodo-1,2,3-triazolyl)phenols has been developed. The key intermediates of the proposed cascade transformation are 2-(1-diazoalkyl)benzoxazoles, entering reductive C-C-coupling with boronic acids. The reaction proceeds under transition-metal-free conditions and affords target compounds in yields up to 67%.
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16

Lauterbach, Thomas, and Detlef Geffken. "Imidazolkatalysierte Ringerweiterung von 2-(Diarylmethyl)- und 2-(ArylaIkyI)-1,2-oxazetidin-3-onen zu 4-Oxazolidinonen / Imidazole-Catalyzed Ring Expansion of 2-(DiaryIm ethyl)- and 2-(Arylalkyl)-1,2-oxazetidin-3-ones to 4-Oxazolidinones." Zeitschrift für Naturforschung B 41, no. 9 (1986): 1186–90. http://dx.doi.org/10.1515/znb-1986-0920.

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Abstract The imidazole-catalyzed ring expansion of 2-(diarylmethyl)- and 2-(arylalkyl)-1,2-oxazetidin- 3-ones 2, easily obtained from the corresponding glycolohydroxamic acids 5, produces 4-oxazolidinones 4 in high yields. In most cases the reaction can be carried out by reacting the hydroxamic acids 5 with 1, 1'-carbonyldiim idazole. Compounds 4a and 4f arise by thermolytic fragmentation of the corresponding perhydro-1,5,2-dioxazinan-3,6-diones 1a, d.
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17

Gevondian, A. G., Y. N. Kotovshchikov, G. V. Latyshev, N. V. Lukashev, and I. P. Beletskaya. "Metal-Free Reductive C–C-Coupling between Arylboronic Acids and 2-(5-Iodo-1,2,3-triazol-1-yl)phenols." Russian Journal of Organic Chemistry 59, no. 9 (2023): 1465–72. http://dx.doi.org/10.1134/s1070428023090026.

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Abstract A new method has been developed for the synthesis of 2-(1-arylalkyl)-1,3-benzoxazoles by coupling of arylboronic acids with 2-(5-iodo-1H-1,2,3-triazol-1-yl)phenols. The proposed cascade process involves intermediate formation of 2-(1-diazoalkyl)-1,3-benzoxazoles and their reductive C–C coupling with arylboronic acids. The procedure requires no transition metal catalysis and provides up to 67% yield of the target products.
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18

Prashad, Mahavir, F. G. Kathawala, and T. Scallen. "N-(Arylalkyl)farnesylamines: new potent squalene synthetase inhibitors." Journal of Medicinal Chemistry 36, no. 10 (1993): 1501–4. http://dx.doi.org/10.1021/jm00062a026.

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19

Xie, Songqiang, Pengfei Cheng, Guangchao Liu, et al. "Synthesis and bioevaluation of N-(arylalkyl)-homospermidine conjugates." Bioorganic & Medicinal Chemistry Letters 17, no. 16 (2007): 4471–75. http://dx.doi.org/10.1016/j.bmcl.2007.06.009.

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20

Lippert, T., J. Dauth, B. Deubzer, J. Weis, and A. Wokaun. "Photolysis of an arylalkyl-triazenido-platinum-IV complex." Radiation Physics and Chemistry 47, no. 6 (1996): 889–97. http://dx.doi.org/10.1016/0969-806x(95)00401-i.

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21

AZZENA, U., S. CARTA, G. MELLONI, and A. SECHI. "ChemInform Abstract: Reductive Lithiation of Arylalkyl Methyl Ethers." ChemInform 29, no. 9 (2010): no. http://dx.doi.org/10.1002/chin.199809085.

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22

Elings, Jacob A., Roger S. Downing, and Roger A. Sheldon. "Cyclialkylation of Arylalkyl Epoxides with Solid Acid Catalysts." European Journal of Organic Chemistry 1999, no. 4 (1999): 837–46. http://dx.doi.org/10.1002/(sici)1099-0690(199904)1999:4<837::aid-ejoc837>3.0.co;2-7.

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23

Amberg, Stefan, and Joachim W Engels. "Synthesis and Properties of Nonpolar DNA (Arylalkyl)phosphonates." Helvetica Chimica Acta 85, no. 8 (2002): 2503–17. http://dx.doi.org/10.1002/1522-2675(200208)85:8<2503::aid-hlca2503>3.0.co;2-i.

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24

Кorobko, Dmytro, Dimitra J. Hadjipavlou-litina, and Liliya `. Logoyda. "ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF A SERIES OF NEW7,8-DISUBSTITUTED THEOPHYLLINE CONTAINING A PYRAZOLE RING." Asian Journal of Pharmaceutical and Clinical Research 11, no. 6 (2018): 448. http://dx.doi.org/10.22159/ajpcr.2018.v11i6.25990.

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Objective: The objective of this study was to synthesize methyl 1-(1,3-dimethyl-2,6-dioxo-7-arylalkyl-(alkenyl-)-2,3,6,7-tetrahydro-1H-purin-8-yl)- 5-(4-methyl-(methoxy-, chloro-)phenyl)-1H-pyrazole-3-carboxylates and studying their antioxidant and anti-inflammatory properties by in vitro methods.Methods: New derivatives of 1,3-dimethylxanthine with pyrazole at position 8 were synthesized by the interaction of 8-bromotheophylline with arylalkyl-(alkenyl) halides, hydrazine hydrate, and methyl 4-(4-R)-2,4-dioxobutanoate. For most obtained compounds, antioxidant activity (by 2,2-diphenyl-1-picry
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25

Haque, Ashanul, Khalaf M. Alenezi, Hani El Moll, Muhammad S. Khan, and Wai-Yeung Wong. "Synthesis of Mixed Arylalkyl Tertiary Phosphines via the Grignard Approach." Molecules 27, no. 13 (2022): 4253. http://dx.doi.org/10.3390/molecules27134253.

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Trialkyl and triaryl phosphines are important classes of ligands in the field of catalysis and materials research. The wide usability of these low-valent phosphines has led to the design and development of new synthesis routes for a variety of phosphines. In the present work, we report the synthesis and characterization of some mixed arylalkyl tertiary phosphines via the Grignard approach. A new asymmetric phosphine is characterized extensively by multi-spectroscopic techniques. IR and UV–Vis spectra of some selected compounds are also compared and discussed. Density functional theory (DFT)-ca
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26

Kanta De, Surya. "RuCl3 Catalyzed Facile Conversion of Arylalkyl Ketoximes to Amides." Synthetic Communications 34, no. 18 (2004): 3431–34. http://dx.doi.org/10.1081/scc-200030648.

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27

Hu, Bin, Meng Meng, John S. Fossey, Weimin Mo, Xinquan Hu, and Wei-Ping Deng. "Optically pure bulky (hetero)arylalkyl carbinols via kinetic resolution." Chemical Communications 47, no. 38 (2011): 10632. http://dx.doi.org/10.1039/c1cc14591f.

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28

Cross, Peter E., John E. Arrowsmith, Geoffrey N. Thomas, Michael Gwilt, Roger A. Burges, and Alan J. Higgins. "Selective class III antiarrhythmic agents. 1. Bis(arylalkyl)amines." Journal of Medicinal Chemistry 33, no. 4 (1990): 1151–55. http://dx.doi.org/10.1021/jm00166a011.

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29

Tolbert, Laren M., Zhaozhao Li, Sarath R. Sirimanne, and Donald G. VanDerveer. "Chemistry of Arylalkyl Radical Cations: Deprotonation vs Nucleophilic Attack." Journal of Organic Chemistry 62, no. 12 (1997): 3927–30. http://dx.doi.org/10.1021/jo961502r.

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30

Katsura, Yousuke, Shigetaka Nishino, Mitsuko Ohno, et al. "Anti-Helicobacter pyloriAgents. 3. 2-[(Arylalkyl)guanidino]-4-furylthiazoles." Journal of Medicinal Chemistry 42, no. 15 (1999): 2920–26. http://dx.doi.org/10.1021/jm9900671.

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31

Geuns, Jan M. C., Marta Ledo Orriach, Rony Swennen, et al. "Simultaneous liquid chromatography determination of polyamines and arylalkyl monoamines." Analytical Biochemistry 354, no. 1 (2006): 127–31. http://dx.doi.org/10.1016/j.ab.2006.03.048.

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32

DENNISON, P. R., A. GIBSON, A. I. GRAY, and G. L. PATRICK. "ChemInform Abstract: Cyclization Studies of 5-Arylalkyl-1,2,3,4,5,6,7,8- Octahydroisoquinolines." ChemInform 28, no. 35 (2010): no. http://dx.doi.org/10.1002/chin.199735162.

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33

Tinapp, Peter, and Ute Groeneveld. "Aminolyse aryl- und arylalkyl-substituierter Cyano-oxirane mit Piperidin." Archiv der Pharmazie 319, no. 12 (1986): 1117–21. http://dx.doi.org/10.1002/ardp.19863191211.

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34

Moriarty, Robert M., and Stuart G. Levy. "Synthesis and resolution of 2-arylalkyl-2-(tetrazol-5-yl)-N-arylalkyl-carboxamides. A new class of chiral sterically hindered tetrazole derivatives." Journal of Heterocyclic Chemistry 32, no. 1 (1995): 155–60. http://dx.doi.org/10.1002/jhet.5570320125.

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35

Kumar, Dinesh, Santosh Rudrawar, and Asit K. Chakraborti. "One-Pot Synthesis of 2-Substituted Benzoxazoles Directly from Carboxylic Acids." Australian Journal of Chemistry 61, no. 11 (2008): 881. http://dx.doi.org/10.1071/ch08193.

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Methanesulfonic acid has been found to be a highly effective catalyst for a convenient and one-pot synthesis of 2-substituted benzoxazoles by the reaction of 2-aminophenol with acid chlorides, generated in situ from carboxylic acids. Aryl, heteroaryl, and arylalkyl carboxylic acids provided excellent yields of the corresponding benzoxazoles. The reaction conditions were compatible with various substituents such as chloro, bromo, nitro, methoxy, cyclopentyloxy, phenoxy, thiophenoxy, and conjugated double bonds. Benzoxazole formation was found to be general with respect to substituted 2-aminophe
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36

Capuano, Ben, Ian T. Crosby, Edward J. Lloyd, Anna Podloucka, and David A. Taylor. "Synthesis and Preliminary Pharmacological Evaluation of 4′-Arylalkyl Analogues of Clozapine. II. Effect of the Nature and Length of the Linker." Australian Journal of Chemistry 56, no. 9 (2003): 875. http://dx.doi.org/10.1071/ch03030.

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We report the synthesis of a second generation of tricyclic analogues of clozapine, investigating the length and nature of the chain between an ionizable nitrogen atom at physiological pH and the introduced aryl moiety. The chemistry, structural characterization, and pharmacological evaluation of this series of 4′-arylalkyl analogues of clozapine are described. Preliminary findings on the effects on activity of the nature and length of the linker, degree of unsaturation, and type of aryl moiety on blockade of dopamine D4 and serotonin 5-HT2A receptors are discussed and animal behavioural data
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37

Bakibaev, А. А., М. Zh Sadvakassova, V. S. Malkov, R. Sh Еrkasov, A. A. Sorvanov, and O. A. Kotelnikov. "Study of the biologically active acyclic ureas by nuclear magnetic resonance." Bulletin of the Karaganda University. "Chemistry" series 100, no. 4 (2020): 60–74. http://dx.doi.org/10.31489/2020ch4/60-74.

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A wide variety of acyclic ureas comprising alkyl, arylalkyl, acyl, and aryl functional groups are investigated by nuclear magnetic resonance spectroscopy. In general, spectral characteristics of more than 130 substances based on acyclic ureas dissolved in deuterated dimethyl sulfoxide at room temperature are studied. The re-sults obtained based on the studies of 1H and 13C NMR spectra of urea and its N-alkyl-, N-arylalkyl-, N-aryl- and 1,3-diaryl derivatives are presented, and the effect of these functional groups on the chemical shifts in carbonyl and amide moieties in acyclic urea derivative
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38

Rasmussen, C. R., F. J. Villani, Jr., L. E. Weaner, et al. "Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas." Synthesis 1988, no. 06 (1988): 456–59. http://dx.doi.org/10.1055/s-1988-27605.

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39

Hazer, Baki, Robert W. Lenz, and R. Clinton Fuller. "Bacterial production of poly-3-hydroxyalkanoates containing arylalkyl substituent groups." Polymer 37, no. 26 (1996): 5951–57. http://dx.doi.org/10.1016/s0032-3861(96)00570-8.

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40

Sari, Suat, Sevim Dalkara, Filiz Betül Kaynak, Jóhannes Reynisson, Selma Saraç, and Arzu Karakurt. "New Anti-Seizure (Arylalkyl)azole Derivatives: Synthesis,In VivoandIn SilicoStudies." Archiv der Pharmazie 350, no. 6 (2017): e201700043. http://dx.doi.org/10.1002/ardp.201700043.

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41

Pashkovsky, F. S., D. I. Korneev, and F. A. Lakhvich. "Transformations of 3,7-interphenylene 11-deoxyprostanoid formyl precursors in the acidic medium." Doklady of the National Academy of Sciences of Belarus 65, no. 6 (2021): 702–7. http://dx.doi.org/10.29235/1561-8323-2021-65-6-702-707.

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It has been shown that the formyl precursors of 3,7-interphenylene 11-deoxyprostanoids, formed during acidic hydrolysis of the corresponding acetals, can undergo isomerization (disproportionation) in the acidic medium to give 2-(arylalkyl)-3-(hydroxymethyl)cyclopent-2-ene-1-ones – the synthons for prostanoids and phytoprostanes of the series B. Acetal precursors of 3,7-interphenylene 11-deoxyprostaglandin analogues with electron-donating alkoxy substituent in position 3′ of the aromatic fragment in the α-chain under similar conditions hydrolyze with the formation of formyl derivatives that spo
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42

Capuano, Ben, Ian T. Crosby, Edward J. Lloyd, Juliette E. Neve, and David A. Taylor. "Aminimides as Potential CNS Acting Agents. II Design, Synthesis, and Receptor Binding of 4′-Arylalkyl Aminimide Analogues of Clozapine as Prospective Novel Antipsychotics." Australian Journal of Chemistry 61, no. 1 (2008): 5. http://dx.doi.org/10.1071/ch07275.

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We report the synthesis of a series of second generation aminimide-based analogues of clozapine, investigating the length of the linker between the aminimide functional group and the introduced aryl moiety. The chemistry and structural characterization of this series of 4′-arylalkyl aminimide analogues of clozapine are described. Preliminary findings on the biochemical effects of linker length and type of aryl moiety on affinity for dopamine D4 and serotonin 5-HT2A receptors are discussed. All of the compounds showed a marked reduction in binding at the two receptors when compared with clozapi
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43

Tolbert, Laren M., Rajive K. Khanna, Ann E. Popp, Leslie Gelbaum, and Lawrence A. Bottomley. "Stereoelectronic effects in the deprotonation of arylalkyl radical cations: meso-ethylanthracenes." Journal of the American Chemical Society 112, no. 6 (1990): 2373–78. http://dx.doi.org/10.1021/ja00162a043.

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44

Novakov, I. A., B. S. Orlinson, D. V. Zavyalov, et al. "Adamantylation of N-aryl and N-arylalkyl acetamides in trifluoroacetic acid." Russian Chemical Bulletin 69, no. 6 (2020): 1096–101. http://dx.doi.org/10.1007/s11172-020-2873-9.

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45

Hwu, Jih Ru, Shwu-Chen Tsay, Buh-Luen Chen, Himatkumar V. Patel, and Ching-Tai Chou. "N-arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents." Journal of the Chemical Society, Chemical Communications, no. 12 (1994): 1427. http://dx.doi.org/10.1039/c39940001427.

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46

Tasnádi, Gábor, Enikő Forró та Ferenc Fülöp. "Improved enzymatic syntheses of valuable β-arylalkyl-β-amino acid enantiomers". Org. Biomol. Chem. 8, № 4 (2010): 793–99. http://dx.doi.org/10.1039/b920731g.

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47

Beger, J., G. Wolniczak, and M. Mühlstädt. "Über die Cyclisierung einiger 2,6-Dimethyl-4-arylalkyl-pyridin-3-carbonsäuren." Zeitschrift für Chemie 2, no. 9 (2010): 274–75. http://dx.doi.org/10.1002/zfch.19620020903.

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48

Hu, Bin, Meng Meng, John S. Fossey, Weimin Mo, Xinquan Hu, and Wei-Ping Deng. "ChemInform Abstract: Optically Pure Bulky (Hetero)arylalkyl Carbinols via Kinetic Resolution." ChemInform 43, no. 6 (2012): no. http://dx.doi.org/10.1002/chin.201206018.

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49

Ma, Jun-Tao, Rong-Hua Huang, Lin Zhao, and Xi Zhang. "Solution properties of ionic hydrophobically associating polyacrylamide with an arylalkyl group." Journal of Applied Polymer Science 97, no. 1 (2005): 316–21. http://dx.doi.org/10.1002/app.21723.

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50

Ukrainets, Igor, Mykola Golik, Lyudmila Sidorenko, et al. "The Study of the Structure—Diuretic Activity Relationship in a Series of New N-(Arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo-[3,2,1-ij]quinoline-5-carboxamides." Scientia Pharmaceutica 86, no. 3 (2018): 31. http://dx.doi.org/10.3390/scipharm86030031.

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Abstract:
In accordance with the principles of “me-too” technique, the preparative method for obtaining has been proposed, and the synthesis of a large series of new N-(arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxamides as structurally close analogs of tricyclic pyrrolo- and pyridoquinoline diuretics has been carried out. All target compounds were obtained with high yields and purity by amidation of ethyl ester of the corresponding 2-methyl-pyrroloquinoline-5-carboxylic acid with arylalkylamines in boiling ethanol. Their structure was confirmed by the data of el
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