Academic literature on the topic 'Arylindoles'

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Journal articles on the topic "Arylindoles"

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Kwon, Yongseok, and Ahreum Kim. "Catalytic Atroposelective Dynamic Kinetic Resolution of Substituted Indoles." Synlett 33, no. 03 (2021): 201–6. http://dx.doi.org/10.1055/a-1694-4695.

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AbstractAdvances in asymmetric catalysis have led to enormous progress in the atroposelective synthesis of axially chiral biaryls. Because of the biological importance of indoles, stereogenic axes in aryl-substituted indoles have attracted considerable research attention in recent years. Here we present a summary of recent advances in the atroposelective synthesis of aryl-substituted indoles by dynamic kinetic resolution. Although several researchers have developed enantioselective syntheses of 3-arylindoles, N-arylindoles have been much less studied. Accordingly, we have developed a Pictet–Sp
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Li, Bin, Beibei Zhang, Xinying Zhang та Xuesen Fan. "Regio-selective synthesis of diversely substituted benzo[a]carbazoles through Rh(iii)-catalyzed annulation of 2-arylindoles with α-diazo carbonyl compounds". Chemical Communications 53, № 7 (2017): 1297–300. http://dx.doi.org/10.1039/c6cc08377c.

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A novel synthetic approach toward benzo[a]carbazoles and 6-aminobenzo[a]carbazoles containing an unprotected NH unit through Rh(iii)-catalyzed cascade reactions of 2-arylindoles or 2-arylindole-3-carbonitriles with α-diazo carbonyl compounds is presented.
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Yuan, Xi, Xudong Wu, Fei Peng, Haijun Yang, Changjin Zhu, and Hua Fu. "Organocatalytic asymmetric synthesis of arylindolyl indolin-3-ones with both axial and central chirality." Chemical Communications 56, no. 83 (2020): 12648–51. http://dx.doi.org/10.1039/d0cc05432a.

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An efficient method for chiral phosphoric acid-catalyzed asymmetric synthesis of arylindolyl indolin-3-ones with both axial and central chirality has been developed via the reaction of 3-arylindoles with 2-aryl-3H-indol-3-ones.
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Arcadi, Antonio, Sandro Cacchi, Giancarlo Fabrizi, et al. "Synthesis of indolo[1,2-c]quinazolines from 2-alkynylaniline derivatives through Pd-catalyzed indole formation/cyclization withN,N-dimethylformamide dimethyl acetal." Beilstein Journal of Organic Chemistry 14 (September 14, 2018): 2411–17. http://dx.doi.org/10.3762/bjoc.14.218.

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An efficient strategy for the synthesis of 6-unsubstituted indolo[1,2-c]quinazolines is described. The Pd-catalyzed reaction ofo-(o-aminophenylethynyl) trifluoroacetanilides with Ar–B(OH)2afforded 2-(o-aminophenyl)-3-arylindoles, that were converted to 12-arylindolo[1,2-c]quinazolines by adding dimethylformamide dimethyl acetal (DMFDMA) to the reaction mixture after extractive work-up. This reaction outcome is different from the previously reported Pd-catalyzed sequential reaction of the same substrates with Ar–I, Ar–Br and ArN2+BF4−, that afforded 12-arylindolo[1,2-c]quinazolin-6(5H)-ones. Mo
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Oeser, Petr, Jakub Koudelka, Artem Petrenko, and Tomáš Tobrman. "Recent Progress Concerning the N-Arylation of Indoles." Molecules 26, no. 16 (2021): 5079. http://dx.doi.org/10.3390/molecules26165079.

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This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles.
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Li, Xu-Qin, Xian-Xing Shang, and Huu-Manh Vu. "One-Pot Synthesis of 2-Arylbenzoxazinones from 2-Arylindoles with (Diacetoxyiodo)benzene as the Sole Oxidant." Synthesis 50, no. 02 (2017): 377–83. http://dx.doi.org/10.1055/s-0036-1590933.

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A series of synthetically interesting 2-arylbenzoxazinones was prepared from 2-arylindoles by an efficient oxidative reaction mediated by (diacetoxyiodo)benzene [PhI(OAc)2] and assisted by water. PhI(OAc)2 was used as the sole oxidant and water was a crucial additive. Our preliminary mechanistic investigations suggest that a water-involved, iodine(III)-promoted sequential oxidation of 2-arylindoles, which was terminated by an interesting Grob-type fragmentation of a fused tricyclic precursor, might be the main components of this one-pot transformation.
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T., V. Sravanthi, and L. Manju S. "An improved Bischler indole synthesis to obtain 2-arylindole scaffolds." Journal of Indian Chemical Society Vol. 92, Jun 2015 (2015): 843–46. https://doi.org/10.5281/zenodo.5631174.

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Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore-632 014, Tamilnadu, India <em>E-mail </em>: slmanju@vit.ac.in In this paper, an economical and improved Bischler indole method to obtain 2-arylindoles in a single step without any catalyst under thermal condition is described. Reaction between &alpha;-bromoarylethanones (1 equi.) and aniline (1 equi.) on reflux in dimethylformamide afforded 2-arylindoles in 85&ndash;90% yield within 20 min. All the synthesized 2- aryl indoles were characterized by spectral analyses such as FT-IR, GC-MS and NMR techniques.
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Nipate, Dhananjay S., Vikki N. Shinde, Krishnan Rangan, and Anil Kumar. "Switchable regioselective hydroalkylation of 2-arylindoles with maleimides." Organic & Biomolecular Chemistry 19, no. 22 (2021): 4910–21. http://dx.doi.org/10.1039/d1ob00690h.

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Liu, Congrong, Lianghui Ding, Guang Guo, Weiwei Liu, and Fu-Lai Yang. "Palladium-catalyzed direct arylation of indoles with arylsulfonyl hydrazides." Organic & Biomolecular Chemistry 14, no. 10 (2016): 2824–27. http://dx.doi.org/10.1039/c5ob02569a.

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Yu, Shuling, Kun Hu, Julin Gong, et al. "Palladium-catalyzed tandem addition/cyclization in aqueous medium: synthesis of 2-arylindoles." Organic & Biomolecular Chemistry 15, no. 20 (2017): 4300–4307. http://dx.doi.org/10.1039/c7ob00572e.

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Dissertations / Theses on the topic "Arylindoles"

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Beaud, Rodolphe. "Hydroarylation régiosélective d’indoles pour l’accès aux motifs 3 - arylindolines : études et applications d’une nouvelle réactivité de l’indole." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA112308/document.

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Le diazonamide A, molécule naturelle extraite d’une ascidie marine, présente une activité antitumorale très importante (IC₅₀ &lt; 5 nM) selon un mode d’action tout à fait original. Des études ont en effet prouvé que cette molécule inhibait une enzyme, l’Ornithine-d-aminotransferase, intervenant dans la réplication cellulaire des cellules cancéreuses faisant d’elle un poison du fuseau mitotique très sélectif. Cette molécule présente en son sein un cœur benzofuroindoline qui serait issu, d’un point de vue biogénétique, d’un couplage oxydant entre un noyau indole et un noyau phénol. Afin de dével
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Books on the topic "Arylindoles"

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Soares-Sello, Anna Mampe. Synthesis of a potential DNA binding compound containing the 2-arylindole ring system. University of East Anglia, 1991.

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Book chapters on the topic "Arylindoles"

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"2-(Hetero)Arylindoles." In Privileged Structures in Drug Discovery. John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781118686263.ch9.

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Camp, J. E. "From 1-Arylindoles." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-117-00114.

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Meigh, J. P. K. "From 1-Arylindoles." In Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-017-01408.

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Conference papers on the topic "Arylindoles"

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Menéndez, J., Vellaisamy Sridharan, Subbu Perumal, and Carmen Avendaño. "Bischler Indole Synthesis under Microwave Irradiation: A Solvent-Free Synthesis of 2-Arylindoles." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01632.

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