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Dissertations / Theses on the topic 'As markers of inflammation'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Cobben, Nicolle Andrée Marie. "Enzymatic markers in monitoring pulmonary inflammation and damage." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 1999. http://arno.unimaas.nl/show.cgi?fid=7213.

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2

Herulf, Max. "Luminal nitric oxide : marker of intestinal inflammation /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4691-4/.

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3

Hyatt, Tanya C. "Ethnic differences in markers of inflammation with weight loss." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2008r/hyatt.pdf.

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4

Dungey, Maurice. "Exercise in haemodialysis patients : impact on markers of inflammation." Thesis, Loughborough University, 2015. https://dspace.lboro.ac.uk/2134/17157.

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End-stage renal disease patients have a greatly increased risk of cardiovascular disease partly attributed to the elevated levels of systemic inflammation observed in uraemia. One of the key mechanisms underlying inflammation appears to be the immune dysfunction that afflicts almost every aspect of the uraemic immune system. As a consequence patients experience immunosuppression and reduced responsiveness to antigen as well as a simultaneous over-activation leading to a pro-inflammatory environment. In addition, the haemodialysis (HD) treatment itself induces a proinflammatory response but may

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5

Welsh, Paul. "Inflammatory markers as novel predictors of cardiovascular disease." Connect to e-thesis, 2008. http://theses.gla.ac.uk/86/.

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Thesis (Ph.D.) - University of Glasgow, 2008.<br>Ph.D. thesis submitted to the Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, 2008. Includes bibliographical references. Print version also available.

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6

Noble, Donald D. "Biophysical, biochemical and cellular markers of airway inflammation in asthma." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/25029.

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Respiratory heat and moisture loss (RHML) is proposed as a novel biophysical marker of AI. In a cross-sectional study of 23 patients with stable persistent asthma, 19 patients with acute asthma and 18 controls, RHML was significantly elevated in stable asthma (p=<0.01) and correlated with sputum eosinophil percentage (r=0.73; p=<0.01). Paradoxically, RHML was not elevated in acute asthma, and a number of possible explanations are discussed. The exhaled gases nitric oxide (NO) and carbon monoxide (CO), and exhaled breath condensate (EBC) pH and nitrite were examined in a cross-sectional s

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7

Maccallum, Niall Samy. "Extracellular myeloperoxidase and markers of inflammation in the sepsis syndromes." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516136.

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8

MacGregor, Gordon. "Non-invasive markers of inflammation in cystic fibrosis lung disease." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4834.

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Cystic fibrosis (CF) lung disease is characterised by early airways infection and inflammation, chronic suppuration, frequent infective exacerbations and an increased influx of acute, and chronic inflammatory cells. The inflammatory process involves activation of many cell types including neutrophils, macrophages and epithelial cells, and leads ultimately to the development of progressive respiratory failure and death. Accurate assessment of the inflammatory process is a crucial part of disease monitoring and should allow appropriate evaluation of therapeutic interventions so as to maximize co

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9

Karim, Salman. "Peripheral and central markers of inflammation in mild cognitive impairment." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/peripheral-and-central-markers-of-inflammation-in-mild-cognitive-impairment(bd21dafe-65c1-42c9-949b-733abfc71037).html.

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There has been accumulating scientific evidence, over the last three decades, of the role of inflammatory processes in the development of Alzheimer's disease (AD). Population based studies suggest that plasma levels of inflammatory markers are raised in peripheral blood of people with AD. People on long term use of non-steroidal anti-inflammatory drugs have a lower prevalence of AD. Moreover, both animal and human histopathology studies have reported localization of inflammation in brain areas primarily affected by AD pathology. Areas of increased inflammation can be visualized in vivo by Posi

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10

Nopp, Anna. "Characterisation of eosinophil activity markers : relation to allergic inflammation and apoptosis /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-129-2.

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11

Kluzek, Stefan. "Markers of synovial inflammation in cohorts at risk of knee osteoarthritis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:3834a171-138d-49e8-84d9-e4fb64adbbd0.

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<b>Background and objectives.</b> Knee osteoarthritis (KOA) is a leading cause of disability in the developed world. Additionally, it is possibly linked with premature mortality. Low-grade inflammation is associated with a high risk of non-traumatic KOA incidence but also with metabolic syndrome. Knee injury is a major risk factor for KOA and is associated with an inflammatory response. Heterogeneity of both the symptoms and progression makes early identification of individuals at risk difficult. The aim of this thesis was to examine the diagnostic value of selected biomarkers to identify micr

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12

Kylänpää-Bäck, Marja-Leena. "Acute pancreatitis : diagnosis and assessment of severity with markers of inflammation." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/kylanpaa-back/.

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13

Potapova, Ekaterina Sergueevna. "Longitudinal evaluation of hemorheological markers in acute inflammatory diseases." Master's thesis, Faculdade de Ciências e Tecnologia, 2014. http://hdl.handle.net/10362/12310.

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Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina<br>Acute myocardial infarction (AMI), sepsis and rheumatoid arthritis (RA) are part of the inflammatory diseases’ group. Every year millions of people are affected and die because of them, all around the globe. In the past years our knowledge of these diseases has increased and a light on their pathophysiology has been shed, but there is still much more to be discovered. Biological markers that would make pre-disease diagnosis possible would change many of the outcomes for patients suffering from them. The aim of

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14

Donati, Mauro. "Gene polymorphisms and related cell markers in periodontitis lesions /." Göteborg : Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, 2009. http://hdl.handle.net/2077/20298.

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15

Whiteley, William Nichol. "Blood markers for the diagnosis and prognosis of stroke." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5609.

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Many blood markers have been associated with stroke. I set out to determine whether blood markers can be applied to: (i) improve the accuracy of the clinical diagnosis of stroke or TIA, and/or (ii) improve the prediction of poor outcome in patients who are still symptomatic at the time of admission with stroke or TIA. I systematically reviewed the existing literature on the diagnostic performance of a range of blood markers measured soon after stroke onset, to inform the choice of markers for my subsequent prospective studies in this thesis. Many studies had deficiencies in their design, which

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16

Manhart, Denise Rae. "Effect of n-3 PUFAs on markers of inflammation in arthritic horses." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1413.

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17

Schölin, Anna. "Diabetes in Young Adults : Remission, β-cell function and markers of inflammation". Doctoral thesis, Uppsala University, Department of Medical Sciences, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3464.

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<p>Type 1 diabetes is caused by immuno-mediated β-cell destruction leading to insulin deficiency and hyperglycaemia. The decline in β-cell function and the clinical course after diagnosis vary. Whether the process of destruction of the β-cells is associated with markers of a non-specific inflammatory response is unknown. The aims of these studies were to identify factors of importance for clinical remission (low insulin need and normoglycaemia) and long-term β-cell function and estimate the degree of non-inflammatory response in type 1 diabetes in young adults. Clinical remission and β-cell fu

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18

Davies, Gary W. "Effects of high pressure breathingfor G-tolerance on airway markers of inflammation." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530479.

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19

Navarro, Trujillo Rodrigo. "Association of inflammation markers in young adult patients with Obsessive-compulsive disorder." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-355094.

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Background: Previous studies have shown that patients with obsessive-compulsive disorder (OCD) have elevated interleukin and chemokine levels in plasma. The purpose of this study was to investigate and validate whether a group of cytokines and chemokines are elevated in a cohort of young adult OCD patients. Methods: A total of 43 patients (11 male/32 female) and 45 controls (15 male/30 female) with OCD were included in the study. The subjects were assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders- Clinical Version or Mini-International Neuropsychiatric Interview. The

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20

Ibba, F. "MARKERS OF INFLAMMATION, IMMUNITY AND RENAL DAMAGE IN DOGS WITH CANINE LEISHMANIASIS." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/247237.

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Canine Leishmaniasis is a zoonotic disease that is spreading over mediterranean basin. Despite the pathogenesis of canine leishmaniasis has been investigated through several studies, some aspect of the host-parasite interaction that lead to overt diseases and typical inflammatory lesions have not yet been understood. Among these, the oxidant-anti-oxidant mechanisms that occur in dogs with the clinical disease are particularly interesting since on one hand they can provide to us useful information on the pathogenesis of the disease, which can also be a model for investigating immune-mediated ch

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21

Cattaneo, Carlo Ignazio. "Mood Disorders and Inflammatory Markers: Pathophysiology and Implications for Treatment." Doctoral thesis, Università del Piemonte Orientale, 2018. http://hdl.handle.net/11579/97206.

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INTRODUCTION: Mood disorders are chronic disorders, responsible for disability worldwide. In recent years a growing body of literature has proposed a psycho-neuro-immunological hypothesis, according to which inflammation may play a role in the development and response to treatment of such diseases. Both Major Depressive Disorder and Bipolar Disorder have been associated with peculiar patterns of cytokine alterations and, on the other hand, some psychotropic drugs showed the ability to affect cytokines production, making an immunomodulatory action of these drugs plausible. METHODS: Our resear

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22

Hallow, Karen Melissa. "Relationships between Mechanical Stress and Markers of Inflammation in Diseased Human Coronary Arteries." Diss., Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/16211.

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Rupture of atherosclerotic plaque is one of the primary causes of death due to cardiovascular disease. The factors directing plaque progression to instability are poorly understood. It is well-known that arteries respond to changes in mechanical stress by remodeling, and that remodeling is mediated by the inflammatory response. Studies have shown that both mechanical stress and markers of inflammation are increased in the fibrous cap and shoulder regions of plaque, where rupture most often occurs. In this study we hypothesized that there are spatial relationships between the local mechanical e

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23

Fernvik, Eva C. "Cell biological mechanisms and activity markers of eosinophils in relation to allergic inflammation /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3399-5/.

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24

Wadley, Alex James. "Exploring changes in markers of oxidative stress and inflammation in response to exercise." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5053/.

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Oxidative stress and inflammation are two reciprocally linked processes that characterise many disease states, but can also transiently increase in response to a range of stimuli, including exercise, to initiate adaptation. This thesis presents novel data indicating that oxidative stress did not increase in response to an acute mental arithmetic challenge, under resting conditions or experimentally induced high baseline inflammation. In the context of exercise, chapters 3, 4 and 5 support previous work that markers of plasma and peripheral blood mononuclear cell (PBMC) oxidative stress increas

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25

Peake, Simon Thomas Charles. "Aberrant expression of homing markers on dendritic cells drives inflammation in Crohn's disease." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/31866.

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CD is a chronic transmural inflammatory disease of the gut. The aetiology of CD is unknown, but is likely to result from dysregulated innate immune responses to gut microbiota leading to over activation of the acquired immune system in a genetically susceptible host. Inflammation occurs anywhere from mouth to anus, in addition to extra-intestinal sites. This compartmentalisation of the inflammatory process is linked to tissue-specific innate immune mechanisms and immune cell homing. DCs play a key role in discriminating between gut commensal microbiota and harmful pathogens, directing T-cell p

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26

Johnston, Sandra K. "Rheumatoid arthritis and major depression : effects of antidepressant therapy on markers of inflammation /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/7230.

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27

Ying, Jiawei [Verfasser], and Bruno [Akademischer Betreuer] Reichart. "Gene expression of inflammation markers in cardiac xenotransplantation / Jiawei Ying ; Betreuer: Bruno Reichart." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1218465646/34.

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28

Airila-Månsson, Stella. "Progression of periodontitis and influence of periodontal bacteria on release of inflammatory markers in Swedish adults /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-622-0/.

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29

Reinders, Claudia I. "Nitric oxide : a surrogate marker of bowel inflammation /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-491-0/.

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30

Planck, Anders. "Sarcoidosis : inflammatory mechanisms and markers of activity /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-355-4/.

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31

Ehrs, Per Olof. "Quality of life and markers of inflammation : a study of asthma in primary care /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-539-9/.

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32

Dernfalk, Johanna. "Multiplex flow cytometric assays for markers of inflammation : development and application in bovine samples /." Uppsala : Dept. of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/20085.pdf.

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33

Shaw, Dominick E. "Non-invasive markers of airway inflammation in the clinical assessment and management of asthma." Thesis, University of Leicester, 2007. http://hdl.handle.net/2381/29537.

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Recently there has been interest in assessing airway inflammation using non-invasive tests as it has been shown that controlling eosinophilic airway inflammation, as measured in induced sputum in a population of patients with moderate to severe asthma, can lead to a reduction in asthma exacerbations, when compared to current guidelines.;Most patients have mild to moderate asthma and are treated solely in primary care, in a setting not suitable for induced sputum measurements; there exists a need for an easy, safe and inexpensive mechanism for monitoring airway inflammation.;Previous work has d

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34

Lanti, C. "ROLE OF BLUEBERRY POLYPHENOLS ON MARKERS OF OXIDATIVE STRESS, INFLAMMATION AND HEPATIC LIPID ACCUMULATION." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/354867.

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Ruolo dei polifenoli del mirtillo sui marker di stress ossidativo, infiammazione e accumulo epatico di lipidi Negli ultimi anni la crescente epidemia di obesità, sindrome metabolica e di malattie cronico-degenerative è diventata un problema emergente nei paesi occidentali con un grave impatto economico sul sistema sanitario. Di conseguenza vi è una forte richiesta di strategie preventive facilmente fruibili dalla popolazione. Lo stile di vita e il comportamento alimentare sono senza dubbio fattori coinvolti sia nello sviluppo sia nella progressione delle malattie croniche. Strategie prevent

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35

Galper, Jasmin. "Inflammatory and lipid markers in clinical and pre-clinical Parkinson’s disease patients." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27967.

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Parkinson’s disease (PD) risk gene discoveries have implicated lipids and inflammation in pathology. However, most research to date has been protein-centric. Therefore, the extent of lipid involvement in PD and relationships between inflammatory and lipid pathways are unclear. Research into these areas may provide novel insights into PD pathology, therapeutic targets and biomarkers for an earlier diagnosis and monitoring disease progression in clinical trials. To investigate lipid dysregulation in PD and in mutation carriers of the PD risk gene LRRK2, untargeted mass spectrometry was perfo

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36

Nyambuya, Tawanda Maurice. "Markers of chronic immune activation and T-cell function in hyperglycaemia." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2597.

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Thesis (MTech (Biomedical Sciences))--Cape Peninsula University of Technology, 2017.<br>Type 2 diabetes mellitus (T2DM) is a chronic inflammatory condition characterised by hyperglycaemia; continuous activation of T-lymphocytes and immune dysregulation. Although the exact mechanisms of these phenomena are not fully understood, there is strong evidence suggesting the involvement of T-cells in the chronic inflammatory environment which could predispose diabetics to infections and thrombotic events. The effect of hyperglycaemia on cells of the innate immune system in T2DM has been well described

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37

Burton, Kate J. "Inflammatory markers, physical activity and exercise tolerance in the adult cystic fibrosis population." Thesis, Griffith University, 2019. http://hdl.handle.net/10072/389845.

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Background & objective: Adults with cystic fibrosis (CF) were assessed to establish whether a relationship exists between inflammation (systemic and/or pulmonary), physical activity and/or exercise tolerance, following in-hospital treatment for an acute exacerbation, and whether these factors can predict for time to next pulmonary exacerbation. In addition to this, demographic information was collected to establish if age, sex, lung function, and/or body mass index is related to the primary study outcomes. Methods: Adults with CF were included following hospitalisation for a pulmonary exacerba

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38

Hamlin, Scott A. "Effects of resistance exercise on markers of inflammation and antioxidant defenses in heart transplant recipients." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0010509.

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39

Irander, Kristina. "An 18 year Follow-up of Allergy Development : Findings of Nasal Markers of Allergic Inflammation." Licentiate thesis, Linköping University, Linköping University, Faculty of Health Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-15853.

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<p><strong>Background:</strong><em><strong> </strong></em>In addition to the family history of allergy (FH), there is a need o find objective markers of allergy development as early in life as possible in order to focus preventive measurements on high risk infants. Rhinitis problems are common causes to morbidity in adults due to allergic as well as non-allergic mechanisms. Accurate diagnoses are essential for decisions of optimal management of the patients, but in non-allergic rhinitis groups there are no objective tests to verify the diagnosis, if this is needed.</p><p><strong>Aims:</strong>

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40

Wulaningsih, Wahyu. "Inflammation and breast cancer : clinical markers and impact on breast cancer incidence, severity and survival." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/inflammation-and-breast-cancer(d98e1522-bc00-488a-8010-33ba59ed4ee4).html.

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This thesis investigated whether inflammation is implicated in breast cancer aetiology and survival. For this purpose, circulating markers of inflammation and inflammatory clinical disorders were studied in relation to the risk, severity, and survival of breast cancer in a large Swedish cohort, the Apolipoprotein MORtality RISk Study (AMORIS), which includes >800,000 participants in Greater Stockholm area. Common inflammatory markers: serum C-reactive protein (CRP), albumin, haptoglobin and white blood cells (WBC) were examined in relation to breast cancer risk and survival using Cox propor

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41

Bourgeois, Marie Meagher. "Gender and Cocaine Use Influence the Expression of Urinary Markers of Inflammation and Oxidative Stress." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3572.

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The purpose of this study was to investigate whether or not gender differences may be present in the expression of a number of urinary proteins which may serve as markers of inflammation and oxidative stress. Males and females have different patterns of illness and different life spans, suggesting basic biological traits exert significant control on the incidence of rhabdomyolysis, renal failure, atherosclerosis, myocardial ischemia, myocardial contraction band formation, autoimmune disorders and general inflammatory diseases. Men are at greater risk for cardiovascular disease; however women,

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42

Гарас, М. Н., Г. В. Лехкун, and Х. І. Климюк. "Markers of inflammation and bronchial hyperresponsiveness in school-age children with severe exercise induced asthma." Thesis, Збірник НПК «Актуальні проблеми практичної та фундаментальної медицини» (Харків, 14 квітня, 2017 року). – Харків, 2017. – С. 5, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13038.

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43

Metso, Tuula. "Detection of intracellular markers in airway inflammation : a biochemical and immunocytochemical study in induced sputum." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/metso/.

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44

COGGI, DANIELA. "RELATIONSHIP BETWEEN PLASMA LEVELS OF PCSK9, VASCULAR EVENTS AND MARKERS OF SUBCLINICAL ATHEROSCLEROSIS AND INFLAMMATION." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/811217.

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Contesto e scopo: La proproteina convertasi subtilisina/kexina di tipo 9 (PCSK9), uno dei principali regolatori del metabolismo del recettore delle LDL, è stata associata allo sviluppo di aterosclerosi. Diversi studi hanno confermato tale associazione attraverso vie lipidiche e non lipidiche. Tuttavia, le relazioni dirette tra PCSK9 circolante e marcatori di aterosclerosi subclinica e clinica sono ancora da chiarire. Pertanto, abbiamo valutato le relazioni tra i livelli plasmatici di PCSK9 ed alcuni indici di aterosclerosi subclinica (marcatori di imaging) e clinica (eventi vascolari; EV). Un

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45

Pennings, Hermanus Johannes. "Biomarkers in asthmatic inflammation a study of pharmacological immunomodulation, in vitro and in vivo /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1999. http://arno.unimaas.nl/show.cgi?fid=6715.

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46

Hosseini, Abolfazl. "Nitric oxide : a marker for inflammation in the lower urinary tract /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-920-X/.

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47

Sainsbury, Anita. "The effect of obesity and weight loss on markers of inflammation and biomarkers of colorectal carcinogenesis." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441194.

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48

Hardaker, Elizabeth Louise. "Effect of a selective IKK2 inhibitor on markers of inflammation both in vitro and in vivo." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427967.

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49

Fleming, Louise Jane. "The Use of Non-Invasive Markers of Inflammation to Guide Therapy in Children with Severe Asthma." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516481.

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50

Flavall, Elizabeth A. "Localisation of antioxidants and oxidative markers within the atherosclerotic plaque." Thesis, University of Canterbury. Biological Sciences, 2008. http://hdl.handle.net/10092/1941.

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Atherosclerosis is a complex inflammatory disease in which oxidative stress is a major protagonist in the development and progression of the atherosclerotic plaque. All biochemical analysis studies of plaque over the past fifteen years have been carried out on whole plaque with no attempt to localise sites of differing biochemical conditions. This study set out to identify in oxidation levels and inflammatory markers in relation to spatial localisation within the plaque. Advanced plaque samples removed during endarectomy were obtained from the Christchurch Hospital Department of surgery and we

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