Contents
Academic literature on the topic 'Asboe-Hansen sign'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Asboe-Hansen sign.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Asboe-Hansen sign"
1
Trisnowati, Dwi M., Hyacintha P. Budi, Shienty Gaspersz, and Meilany Durry. "Bullous Pemphigoid Treated with Corticosteroid: A Case Report." e-CliniC 10, no. 2 (2022): 400. http://dx.doi.org/10.35790/ecl.v10i2.41403.
Full textAbstract:
Abstract: Bullous pemphigoid (BP) is an autoimmune disease clinically characterized by pruritic, large, tense subepidermal bullae over normal skin, erythematous or urticarial plaques. The pathogenesis related to the immune system towards BP antigen 180 and 230. Mild lesions may be treated with topical corticosteroid but the more extensive lesions are treated with oral corticosteroids. We reported a case of 58-year-old man came with clear fluid-filled blisters on the body since a week ago. Dermatological examination revealed multiple vesicle-bullae, filled with clear fluid, tense walls. Nikolsky sign and Asboe-Hansen sign were negative. Histopathological examination supported the diagnosis of BP. Diagnosis was established based on anamnesis, and physical and histopathological examinations. The patient was treated with systemic corticosteroid due to the consideration of the extensive lesions. Methylprednisolon was given intravenously at a dose of 43.75 mg per day which was then replaced orally for tapering off. The dose reduction of 4 mg per week was carried out according to the clinical improvement. In conclusion, this case improved after being treated with systemic corticosteroid for approximately 2-3 months.Keywords: bullous pemphigoid; corticosteroid Abstrak: Pemfigoid bulosa (PB) merupakan penyakit bula autoimun ditandai dengan pruritus dan bula subepidermal besar berdinding tegang di atas kulit yang normal, eritematosa atau plak urtikaria. Patogenesisnya berhubungan dengan sistem kekebalan tubuh yaitu respons imun terhadap antigen BP 180 dan 230. Penatalaksanaan untuk lesi ringan diberikan kortikosteroid topikal, sedangkan untuk lesi luas dengan kortikosteroid sistemik. Kami melaporkan seorang laki-laki berusia 58 tahun dengan keluhan lepuh-lepuh berisi cairan jernih pada hampir seluruh tubuh sejak satu minggu lalu. Pada pemeriksaan fisik ditemukan vesikel-bula, multipel, berisi cairan jernih, dinding tegang. Pemeriksaan tanda Nikolsky dan Asboe-Hansen negatif. Pemeriksaan histopatologik mendukung diagnosis PB. Tatalaksana yang diberikan berupa kortikosteroid sistemik karena pertimbangan lesinya yang luas. Metilprednisolon diberikan secara intravena dengan dosis 43,75 mg per hari yang kemudian diganti pemberian per oral saat tapering off. Penurunan dosis 4 mg metilprednisolon per minggu dilakukan sesuai dengan perbaikan kondisi klinis. Simpulan kasus ini ialah pemfigoid bulosa yang mengalami perbaikan setelah diterapi dengan kortikosteroid sistemik selama kurang lebih 2-3 bulan.Kata kunci: pemfigoid bulosa; kortikosteroid
2
Taniowas, Paul O., Tara S. Kairupan, Marlyn G. Kapantow, and Aryani Adji. "Bullous Pemphigoid in a Women with Type 2 Diabetes Mellitus: A Case Report." e-CliniC 10, no. 1 (2022): 131. http://dx.doi.org/10.35790/ecl.v10i1.39085.
Full textAbstract:
Abstract: Bullous Pemphigoid (BP) is an autoimmune disease with subepidermal blisters that are generally minimally itchy to non-itchy. It usually occurs in old age, but sometimes in children and young adults. Clinical presentation shows large, tense-walled blisters on normal or erythematous skin, mostly at the folds, lower abdomen, thighs, but they can appear anywhere. Therapy of BP is aimed to treat skin and mucous lesions as soon as possible and to reduce itchiness, therefore, the quality of life will be improved. The first line therapy is oral and topical corticosteroids, with an initial dose of prednisone 0,75-1mg/kg/day or less. Prednisone tapering should be carried out in accordance with the clinical response and side effects. We reported a 47-year-old female, complained blisters on chest, abdomen, both arms and legs simultaneously. History of uncontrolled diabetes mellitus was present. Skin biopsy revealed subepidermal bullae associated with infiltraton of inflammatory cells, and Nikolsky sign and Asboe-Hansen sign showed negative results. Based on the results, the patient was diagnosed as BP. Prednisone was given 40mg/day with weekly tapering. After two weeks of prednison therapy, the lesions showed great improvement. After six weeks of therapy, the blister formation stopped, and a gradual tapering-off of the corticosteroid dose was recommended according to clinical responses until three months of therapy. The blisters reduced without any side effects. In this case, prednisone showed good result, and complete resolution occurred after six weeks of therapy.Keyword: bullous pemphigoid; diabetes mellitus; prednisone Abstrak: Pemfigoid Bulosa (PB) merupakan penyakit autoimun dengan lepuh subepidermal yang umumnya gatal minimal hingga tidak gatal, lebih sering terjadi pada usia tua, kadang pada anak dan dewasa. Gambaran klinis berupa lepuh besar, dinding tegang di atas kulit normal atau dasar eritematosa. Biasanya ditemukan di lipatan, perut, paha, tetapi bisa muncul di mana saja. Terapi PB bertujuan untuk menyembuhkan lesi kulit dan mukosa dengan cepat dan mengurangi rasa gatal untuk meningkatkan kualitas hidup. Penggunaan kortikosteroid oral dan topikal merupakan lini pertama, dengan dosis awal prednison 0,75-1mg/kg/hari atau kurang. Tapering prednison harus dilakukan sesuai dengan respon klinis dan efek samping. Kami melaporkan kasus seorang wanita, 47 tahun, dengan keluhan lepuh-lepuh di dada, perut, kedua lengan dan kaki muncul bersamaan dengan riwayat diabetes melitus tidak terkontrol. Biopsi kulit dilakukan dengan hasil bula subepidermal disertai infiltrasi sel inflamasi. Nikolsky sign dan Asboe-Hansen sign memberikan hasil negatif. Pasien didiagnosis sebagai PB dan diberikan prednison 40 mg per hari dengan tapering per minggu. Setelah dua minggu terapi prednison, lesi menunjukkan banyak perbaikan. Setelah enam minggu terapi, pembentukan lepuh terhenti, dan dilakukan pengurangan dosis prednison secara bertahap sesuai respons klinis sampai tiga bulan terapi. Lepuh berkurang tanpa efek samping. Pada kasus ini, prednison memberikan hasil yang memuaskan, dan resolusi lengkap tercapai setelah enam minggu terapi.Kata kunci: pemfigoid bulosa; diabetes mellitus; prednison
3
Dr, Jatin Gupta. "Nikolskiy's Sign - A Review." RESEARCH REVIEW International Journal of Multidisciplinary 03, no. 06 (2018): 134–35. https://doi.org/10.5281/zenodo.1258192.
Full textAbstract:
Autoimmune skin disorders sometimes are characterized by acantholysis, or loss of the normal epithelial cell-to- cell adhesion within the skin(8). Clinically, these disorders present with blistering of the skin and include the pemphigus and pemphigoid groups of disorders. On visual inspection only, these skin conditions are difficult to diagnose and may be confused with other types of skin disorders. Nikolskiy"s sign is a well described clinical sign that can be helpful in differentiating some of the autoimmune skin disorders and even determining their prognosis(9).This article presents the original description of Nikolskiy's sign given by Piotr Vasiliyevich Nikolskiy in 1894, along with various different interpretations of Nikolskiy's sign and numerous terminologies used in the literature by a number of clinicians.
4
Aviana, Felicia, and I. Made Birawan. "Steroid-induced diabetes mellitus in pemphigus vulgaris patient at Bali Mandara Hospital: a case report." Bali Dermatology and Venereology Journal 4, no. 2 (2021). http://dx.doi.org/10.15562/bdv.v4i2.43.
Full textAbstract:
Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case.Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%. Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin.Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.
5
Felicia Aviana and I Made Birawan. "Steroid-induced diabetes mellitus in pemphigus vulgaris patient at Bali Mandara Hospital: a case report." Bali Dermatology Venereology and Aesthetic Journal, January 12, 2023, 28–31. http://dx.doi.org/10.51559/8vc5nd62.
Full textAbstract:
Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case.
 Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%. Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin.
 Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.
6
Ni Kadek Setyawati, A. A. I. A. Nindya Sari, and Pande Agung Mahariski. "Glucocorticoid-induced hyperglycemia (GIH) in pemphigus vulgaris patient at Bangli District General Hospital: A case report." Bali Dermatology Venereology and Aesthetic Journal, November 28, 2022, 28–33. http://dx.doi.org/10.51559/b53b1w20.
Full textAbstract:
Background: Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous blistering and erosion. This is rare, but greatly affects the patient’s life quality and often cause complication of disease and therapy. Hyperglycemia is a complication due to steroid use called glucocorticoid-induced hyperglycemia (GIH). This case report describes hyperglycemia in PV treatment, which later can be a consideration of PV management.
 Case: A 44-year-old male patient complained of painful lesions on almost the whole body with a form of bullae, erosion, crusting, brittle, the Nikolsky sign (+), and Asboe-Hansen sign (+). The patient was diagnosed with PV. After he had supportive therapy and high-doses of methylprednisolone, his blood sugar is increased. Patients diagnosed by hyperglycemia state due to steroid use, then given insulin as therapy. The patient diagnosed with PV based on history taking and physical examination, but the histopathologic examination wasn’t done due to lack of modality at the hospital. The steroid was given as an immunosuppressive. Be the main therapy for PV, steroids lead hyperglycemia due to disruption of glucose metabolism, thereby increasing insulin resistance in tissues. The diagnosis of hyperglycemia due to steroid use is made in a patient with a normal sugar level before PV therapy. It occurred within the first 1-2 days of therapy. In these patients, diagnosis confirmed by increasing pre-prandial, 2 h post-prandial, and any-time glucose level, after two days methylprednisolone administration. Collaboration with internal medicine colleagues is needed.
 Conclusion: PV treatment with steroids can induce hyperglycemia, which is dangerous. The understanding mechanism is needed to make early detection and provide therapy properly.
7
Laura, Elena Leon Islas M.D., Ivan Maya Talamante M.D. Edwin, and Luna Reyes M.D. Alejandro. "Toxic epidermal necrolysis following SARS-CoV2 vaccine. A case report." August 22, 2023. https://doi.org/10.5281/zenodo.8274636.
Full textAbstract:
<strong>Background</strong> 66-year-old female with a history of arterial hypertension of 3 months of diagnosis and colon cancer of 13 years of diagnosis with partial colectomy on two occasions and second-line treatment with imatinib from 2018 to June 2021 with subsequent change to sunitinib in September of 2021 for presenting a recurrence, who received the vaccination schedule against SARS-CoV2 with a third dose from the Pfizer laboratory applied on November 11, 2021. Symptoms began approximately 18 hours after the administration of the vaccine with pain at the application site, after After 24 hours, intense itching was added, lesions on the oral and ocular mucosa made up of ulcers, later he presented multiple red erythematous macules that spread in a cephalo-caudal direction, forming blisters and flaccid blisters of 3 to 25 cm in diameter, some de-epithelialized, forming superficial ulcers. , Nikolsky sign and positive Asboe-Hansen in addition to acute kidney injury. She received treatment with fluid replacement, antihypertensive management, corticosteroids, analgesics, and cleaning of the wounds with antiseptic dressings and hydrocolloid patches in the most extensive lesions, monitoring of the hemodynamic pattern, and evaluation by ophthalmology with the application of antibiotics, steroids, and artificial tears. With the improvement of the clinical picture, progressive weaning of the corticosteroid was carried out and discharge from the intensive care unit was decided. No recurrences were reported after discharge. <strong>Keywords:</strong> SARS-CoV2 vaccine, Toxic epidermal necrolysis.
8
Nopriyati, Nopriyati, Sarah Diba, Athuf Thaha, Rusmawardiana Rusmawardiana, Inda Astri Aryani, and Damai Trilisnawati. "Antituberculosis Drug-induced Linear IgA Dermatosis." Journal of Skin and Stem Cell In Press, In Press (2021). http://dx.doi.org/10.5812/jssc.115782.
Full textAbstract:
Introduction: Linear IgA dermatosis is a rare autoimmune vesiculobullous disease characterized by homogeneous linear IgA deposits in basement membrane of epidermis, and it can be idiopathic or drug-induced. The pathogenesis of drug-induced linear IgA dermatosis is not fully known yet, but it is associated with specific T cells. The clinical manifestations of the disease include vesiculobullous eruption, erythematous plaques, or string of pearls. Most cases still need additional therapy to avoid the expansion of the disease. Case Presentation: In this study, we present a 17-year-old male patient with erythema plaques, vesicles, and bullae with erosion in facial, oral, neck, trunk, genital, and extremities, pruritus, and burning sensation. The patient was undergoing pulmonary tuberculosis (TB) treatment for one week. Physical examination was done, and total BSA 10% and negative Asboe-Hansen sign were seen. The treatment consisted of delaying administration of TB drugs, desoximetasone cream 0.25%, cetirizine 10 mg, and aspiration of bullae. Conclusions: Drug-induced linear IgA dermatosis can occur at any age due to the administration of rifampicin and other antibiotics, angiotensin-I converting enzyme (ACE) inhibitors, or nonsteroidal anti-inflammatory drugs (NSAIDs). The drug can stimulate specific T cells that release Th2 cytokines to produce IgA antibodies against the basement membrane of epidermis. Drugs may cause an autoimmune response by cross-reaction with the target epitope, altering the conformation of epitopes, or exposing previously sequestered antigens to the immune system. The causative drug was stopped, and methyl prednisolone 0.5 - 1 mg/kg/day was given as initial therapy. In this study, we reported a rare case of a 17-year-old male with anti-TB drug-induced linear IgA dermatosis. Diagnosis was done based on clinical manifestation, histopathology, and immunofluorescence. The causative drug was stopped, the patient was given topical and systemic steroid therapy and drug desensitization. Remission was noted after six weeks of therapy, and oral steroid was slowly tapered and stopped on day 42. After stopping oral steroids, no lesions were reported. A 6-month follow-up revealed no signs of recurrence.