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1

Chao, Sheng-Hao. "Heat Shock Proteins in Ascaris suum." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc279311/.

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Ascaris suum were exposed to a number of stressors, including heavy metals and both high (40°C) and low (18°C) temperatures. The 70kD and 90kD heat shock proteins (HSPs) in the different A. suum tissues were analyzed by Western blot and quantitated by Macintosh Image Program.
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2

Capizzi-Banas, Sandrine. "Oeuf d'ascaris Suum : Approches structurales et environnementales." Nancy 1, 2000. http://www.theses.fr/2000NAN12002.

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3

Coates, Shana. "Modelling the population dynamics of Ascaris suum in pigs." Thesis, University of Warwick, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365228.

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4

Pettitt, Jonathan. "Structure and expression of collagen genes in Ascaris suum." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240197.

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5

Williamson, Sally. "Nicotinic acetylcholine receptors from the parasitic nematode Ascaris suum." Thesis, University of Bath, 2008. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501371.

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Nematodes of the genus Ascaris are large gastrointestinal parasites. Ascaris lumbricoides infects ~1 billion people globally; causing malnutrition and general morbidity, and can block the gut or bile duct causing fatal complications. Ascaris suum is a parasite of pigs; in addition to its veterinary significance, it can occasionally be zoonotic, and is a good model of the human parasite. One of the main classes of drugs used to treat parasitic nematode infections are the cholinergic anthelmintics, such as levamisole and pyrantel, which act as agonists of nicotinic acetylcholine receptors at the
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6

Hannigan, Linda L. (Linda Lucile). "Purification and characterization of glycogen synthase from Ascaris suum." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc798067/.

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Glycogen synthase, the enzyme that catalyzes the rate-limiting reaction of glycogen syntheses has been purified and characterized from Ascaris suum muscle. Glycogen in the crude extract was digested to release the enzyme, eluted from a DE52 cellulose column and then applied to a Sepharose affinity column. The purified Ascaris enzyme was found to be homologous to the mammalian enzyme with regard to subunit and holoenzyme Mr^3 allosteric activation, substrate affinity and covalent modification. However, the association between Ascaris glycogen synthase and endogenous glycogen differed from that
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7

Beckett, A. M. "Studies on the neuropeptidergic system of nematodes." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269161.

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8

Heath, A. Chris. "Structure and function relationships in a complex synthesizing glycogen de novo from Ascaris suum." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc798120/.

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9

Holowiecki, Andrew. "Catalysis of mitochondrial NADH:NAD+ transhydrogenation in adult Ascaris suum (nematoda)." Bowling Green, Ohio : Bowling Green State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1256953439.

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10

Chehayeb, James. "Proteomic analysis of «Ascaris suum» fluid compartments and secretory products." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123155.

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Ascaris lumbricoides infects at least 10% of the world's population and is a public health issue in most low-to-middle income countries. Survival of this parasite in its host is mediated at least in part by materials exported to the host in secretions. Although very little is known about the composition of these secretions, defining their contents and functions could shed light on the host-parasite interactions that lead to parasite establishment and persistence in the host. Ascaris suum, a parasite of pigs, was used as a model organism because its genome has been sequenced and it is closely r
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11

Payne, Marvin A. "Desensitized Phosphofructokinase from Ascaris suum: A Study in Noncooperative Allostery." Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc279174/.

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The studies described in this dissertation examine the effects of F-2,6-P2 and AMP or phosphorylation on the kinetic mechanism of d-PFK. The effect of varied pH on the activation by F-2,6-P2 is also described.
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12

Thorn, Peter. "An electrophysiological study of the somatic muscle cells of Ascaris suum." Thesis, University of Edinburgh, 1989. http://hdl.handle.net/1842/30027.

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13

Paterson, Jacqueline C. M. "Modulation of T cell responses by the products of Ascaris suum." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312783.

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14

Brooman, Julie Elizabeth. "The characterisation of serotonin receptors in the parasitic nematode Ascaris suum." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242710.

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15

Parri, Harri Rheinallt. "Studies on chloride in the muscle bag cells of Ascaris suum." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238844.

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16

Duittoz, Anne Helene. "Pharmacology of GABA receptors in Ascaris suum muscle : an electrophysiological study." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/29738.

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The aim of this work is to describe the pharmacological profile of the <i>Ascaris</i> muscle GABA receptor, and to compare its properties to those of GABA receptors in vertebrates. The interest of such study is to show the existence of pharmacological differences between <i>Ascaris</i> and vertebrate GABA receptors, which may be exploited in antiparasitic drug research. The effects of GABA and various GABA-agonists on the membrane input conductance of <i>Ascaris</i> muscle cells were studied using a current-clamp technique. Dose-response curves were obtained and described by a modified Hill eq
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17

Ferreira, Sebastião Rodrigo. "Atividade ovicida do fungo Pochonia chlamydosporia sobre ovos de Ascaris suum e atividade predatória de fungos nematófagos sobre formas infectantes de Oesophagostomum spp." Universidade Federal de Viçosa, 2011. http://locus.ufv.br/handle/123456789/5071.

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Made available in DSpace on 2015-03-26T13:46:59Z (GMT). No. of bitstreams: 1 texto completo.pdf: 2273628 bytes, checksum: 5b1679c5e47e66a87032a8293b4946e0 (MD5) Previous issue date: 2011-08-15<br>Swine meat is one of main sources of animal protein consumed in the world and strong demand for swine meat in the Asian continent has stimulated the development of the internal market, however, has been demanded a production system aimed at animal welfare and organic production. Even though, in given situations intestinal parasites remain a problem for breeding these animals, especially when this i
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18

Leite, Ana Karine Rocha de Melo. "Efeito protetor dos extratos de Ascaris suum e Coccidioides posadasii e da lectina da semente de Dioclea violacea na artrite por zymosan em ratos e camundongos." reponame:Repositório Institucional da UFC, 2009. http://www.repositorio.ufc.br/handle/riufc/847.

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LEITE, Ana Karine Rocha de Melo. Efeito protetor dos extratos de Ascaris suum e Coccidioides posadasii e da lectina da semente de Dioclea violacea na artrite por zymosan em ratos e camundongos. 2009. 70 f. Tese (Doutorado) - Universidade Federal do Ceará. Faculdade de Medicina. Programa de Pós-Graduação em Ciências Médicas, Fortaleza, 2009.<br>Submitted by denise santos (denise.santos@ufc.br) on 2011-10-05T13:37:05Z No. of bitstreams: 1 2009_tese_akrmleite.pdf: 1567980 bytes, checksum: 9f13d2575ffdfa87c6cfdfc7a9ccfc75 (MD5)<br>Approved for entry into archive by Eliene Nascimento(elienegvn@h
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19

Hsu, Shing-Chien. "The bacterial flora of the intestine of Ascaris suum and serotonin production." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc798353/.

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20

Araújo, Claudia Andréa Alves de. "Estudos da imunomodulação induzida por PAS-1 (proteína imunossupressora de Ascaris suum) na inflamação alérgica pulmonar." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-18102007-103406/.

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Neste trabalho, investigamos os mecanismos da resposta imune estimulados por PAS-1 para o desencadeamento do seu efeito modulatório na inflamação alérgica pulmonar. Para tanto, camundongos C57BL/6 selvagens, IL-12-/-, IFN-<font face=\"Symbol\">g-/- e IL-10-/- foram imunizados e desafiados com OVA ou PAS-1 ou OVA + PAS-1. Ainda, camundongos C57BL/6 imunizados e desafiados com OVA receberam transferência adotiva de células CD19+, B220+, CD3+, CD4+, CD8+, CD4+CD25-, CD4+CD25+ PAS-1-primadas. Nossos resultados demonstraram que o efeito imunomodulatório de PAS-1 é mediado por IFN-<font face=\"Symbo
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21

Tian, Li, and 田莉. "Structural analysis of thymidylate synthase in nematodes: ascaris suum & caenorhabditis elegans." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31237757.

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22

Tian, Li. "Structural analysis of thymidylate synthase in nematodes : ascaris suum & caenorhabditis elegans /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20007413.

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23

Holowiecki, Andrew. "Catalysis of Mitochondrial NADH→NAD+ Transhydrogenation in Adult Ascaris suum (Nematoda)." Bowling Green State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1256953439.

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24

Martin, Rex E. (Rex Edward). "Neuroregulation and Myosin Light Chain Phosphorylation in Ascaris Suum Obliquely Striated Skeletal Muscle." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc504635/.

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Extraction and quantitation of myosin light chain two coupled with myograph recordings from Ascaris muscle perfused with calmodulin inhibitors and neurotransmitters in conjunction with their respective agonists and antagonists have been used to establish the regulation of contraction in this muscle. Densitometric tracings of isolectric focusing gels separating the regulatory light chain were used to quantitate phosphorylation in resting, contracted and flaccid muscle. These studies indicated that inhibitory neurostimulation is mediated by a true GABA receptor. Myosin-mediated contraction is re
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25

Papaioannou, Sylvana. "Physiological actions of putative neuropeptides in the nematodes Ascaris suum and Caenorhabditis elegans." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441564.

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26

Purcell, Jenny. "The effects of PF4 on Ascaris suum somatic muscle cells : an electrophysiological study." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/29954.

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PF4 is a FaRP which was isolated from the free-living nematode <i>Panagrellus redivivus </i>and which has been shown to have activity in other nematodes, including <i>Ascaris suum</i>. <i>A. suum</i>, the large parasitic nematode found in domestic pigs, is often used as an experimental model in studying nematodes due to its large size and easy availability. The nematodes used in this study were obtained from three different sources. The action of PF4 on the somatic muscle cells of <i>A.suum </i>was investigated using the two electrode current clamp technique. PF4 caused these cells to hyperpol
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27

Pinto, Ana Carolina Matias Dinelly. "Efeito anti-inflamatório e imunomodulador de componentes de ascaris suum em artrite experimental." reponame:Repositório Institucional da UFC, 2017. http://www.repositorio.ufc.br/handle/riufc/24185.

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PINTO, A. C. M. D. Efeito anti-inflamatório e imunomodulador de componentes de ascaris suum em artrite experimental, 2017.118 f.Tese (Doutorado em Ciências Médicas) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2017<br>Submitted by Ivone Sousa (ppgcm.ufc@gmail.com) on 2017-07-21T13:27:56Z No. of bitstreams: 1 2017_tese_acmdpinto.pdf: 10927136 bytes, checksum: 4648aa6dab4dc5fb388eac8229d92bb9 (MD5)<br>Approved for entry into archive by Erika Fernandes (erikaleitefernandes@gmail.com) on 2017-07-21T15:51:59Z (GMT) No. of bitstreams: 1 2017_tese_acmdpinto.pdf: 10927136 bytes,
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28

Franks, Christopher John. "Studies on the actions of the nematode FMRFamide like neuropeptide PF1." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243920.

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29

Buxton, Samuel. "Parasitic nematode ion channels : improving understanding of pharmacology and genetic composition." Thesis, Tours, 2012. http://www.theses.fr/2012TOUR4047/document.

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Actuellement, les infections des humains, des plantes et des animaux par les nématodes parasites ont un impact économique majeur. En l’absence de vaccin efficace, les anthelminthiques sont les principaux agents chimiothérapeutiques utilisés pour le traitement et la prophylaxie des infections à nématodes. Cependant, la résistance est apparue pour la plupart des anthelminthiques. Par conséquent il est urgent de comprendre la génétique des récepteurs ciblés par ces anthelminthiques et de trouver des cibles alternatives afin de développer de nouveaux anthelminthiques. Nous avons démontré les effet
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30

Qian, Hai. "Nematode nicotinic acetylcholine receptors a single-channel study in Ascaris suum and Caenorhabditis elegans /." [Ames, Iowa : Iowa State University], 2007.

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31

Fausto, Mariana Costa. "Ascaris suum: diagnóstico, controle alternativo e levantamento na microrregião de Ponte Nova - Minas Gerais." Universidade Federal de Viçosa, 2015. http://www.locus.ufv.br/handle/123456789/6528.

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Submitted by Amauri Alves (amauri.alves@ufv.br) on 2015-11-04T16:49:40Z No. of bitstreams: 1 texto completo.pdf: 1298895 bytes, checksum: 72e4c92a5bd8740f6d06d50d7527f588 (MD5)<br>Made available in DSpace on 2015-11-04T16:49:40Z (GMT). No. of bitstreams: 1 texto completo.pdf: 1298895 bytes, checksum: 72e4c92a5bd8740f6d06d50d7527f588 (MD5) Previous issue date: 2015-03-05<br>O setor suinícola brasileiro tem enfrentado nos últimos anos, barreiras para exportação da carne, principalmente relacionadas a questões sanitárias e ao bem-estar animal. Em relação às questões sanitárias, grande desta
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32

Favoretto, Bruna Cristina. "Estudo da participação dos receptores DC-SIGN e MR nos mecanismos de supressão da resposta imune induzida por componentes de alta massa molecular do extrato de Ascaris suum." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-27112014-104232/.

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Antígenos de alta massa molecular (PI) do extrato de Ascaris suum exercem efeito supressor sobre a resposta imune a antígenos heterólogos. PI atua diretamente sobre as DCs, diminuindo a expressão das moléculas coestimuladoras, MHC de classe II e assim, a proliferação de linfócitos T. Esse efeito é independente de TLR2, TLR4 e da molécula MyD88. Nesse trabalho estudamos a participação dos receptores DC-SIGN e MR, na modulação da atividade das DCs. PI contém oligossacarídeos N-ligados com cadeias de alta manose e do tipo complexa e contém resíduos de fosforilcolina. Os componentes do PI contend
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33

Souza, Valdênia Maria Oliveira de. "Propriedades imunorreguladoras de extratos solúveis obtidos de vermes adultos ou de ovos de Ascaris suum." Universidade de São Paulo, 1999. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-28032001-145248/.

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O extrato de Ascaris suum (Asc total), preparado a partir de uma mistura de vermes machos e fêmeas (albergando ovos), suprime a resposta imune específica a ovalbumina (OA). A partir do fracionamento deste extrato por gel filtração demonstrou-se que componentes protéicos de alto peso molecular (PM), eluídos no primeiro pico (PI), eram supressores da resposta a OA e os eluídos no terceiro pico (PIII) estimularam uma resposta maior de anticorpos IgE anti-Asc. Uma resposta do tipo Th2 foi preferencialmente estimulada por este extrato, sendo as citocinas IL-4 e IL-10 atuantes na supressão dos parâm
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34

Corfield, Gaynor Christa. "The regulation and characterization of porcine IgE." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319081.

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35

Fellows, Rosalind A. "Studies on the neuromusculature of the gonoduct and pharynx of the nematode parasite, Ascaris suum." Thesis, Queen's University Belfast, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326429.

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36

Verma, Saurabh. "Voltage-activated currents and their modulation in somatic muscle cells of the nematode Ascaris suum." [Ames, Iowa : Iowa State University], 2008.

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37

Silva, Aldacilene Souza da. "Anticorpos anafiláticos induzidos por componentes de alto peso molecular de Ascaris suum: regulação da resposta primária e secundária por citocinas." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-19092018-110326/.

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Estudos anteriores mostraram um efeito supressivo do extrato de Ascaris suum (Asc) nas respostas humoral e celular a um antígeno heterólogo. O fracionamento deste extrato por gel filtração possibilitou a identificação de picos distintos, constituídos de proteínas de alto peso molecular (PI) e baixo peso molecular (Plll), sendo o efeito supressivo de Asc restrito aos componentes de PI. Com relação à produção de anticorpos contra estes componentes, verificou-se que PI é capaz de induzir preferencialmente a síntese de lgG1 não-anafilática e baixos títulos de lgE e de lgG1 anafilática. Considerand
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38

Martin, Rex E. (Rex Edward). "Localization of serotonin (5-hydroxytryptamine, 5-HT) with partial purification and characterization of a serotonin binding protein in the intestinal tissue of the nematode Ascaris suum." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc798477/.

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Muscle, hypodermis and gastrointestinal epithelium from adult female Ascaris lumricoides var. summ were found to contain serotonin based upon glyoxylic acid induced histofluorescence and indirect immunolabeling with an anti-serotonin monoclonal antibody conjugated to protein A-colloidal gold.
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39

Mallick, Sushanta. "Kinetic mechanism of NAD-malic enzyme from Ascaris suum in the direction of reductive carboxylation of pyruvate." Thesis, University of North Texas, 1990. https://digital.library.unt.edu/ark:/67531/metadc332658/.

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For this pseudoquadreactant enzymatic reaction (Mn2+ is a psuedoreactant), initial velocity patterns were obtained under conditions in which two substrates were maintained saturating while one reactant was varied at several fixed concentrations of the other.
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40

Bughio, Nasreen Inayat. "Production and characterization of monoclonal antibodies against tubulin from intestinal and tissue nematodes (Ascaris suum & Brugia pahangi)." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70284.

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Monoclonal antibodies (MAbs) have been raised against $ beta$-tubulin of B. pahangi and A. suum. Anti-B. pahangi MAbs were used to investigate the heterogeneity of tubulins from nematodes and mammals. One-dimensional SDS-PAGE showed that MAbs P3D and 1B6 react with $ beta$-tubulin from a number of filarial and intestinal nematodes, but not with tubulin from protozoan and mammalian cells. Two-dimensional SDS-PAGE demonstrated that MAb P3D recognizes two isoforms of $ beta$-tubulin and 1B6 recognizes one. Limited proteolysis showed that MAb 1B6 reacted with the amino-terminal fragments and MAb P
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41

Colquhoun, Lorna Mairi. "Studies on the nicotinic receptor on the somatic muscle cells of the parasitic nematode Ascaris suum." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359232.

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42

Silva, Caroline Cavalcanti da. "Influência do óxido nítrico na infecção experimental por Ascaris suum durante a fase inicial da ascaridíase." Universidade Federal de Minas Gerais, 2014. http://hdl.handle.net/1843/BUBD-9P3FCL.

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Ascariasis is the most common geohelminth infection worldwide. The biological aspects related to ascariasis are remain unclear, as well as immunological and histopathological mechanisms, especially during the early phase of infection. Several studies have shown that nitric oxide is involved as a mediator in other parasitic infections and also affects the survival of the parasites in the host. Thus, the goal of this work was to study the influence of nitric oxide during the early stage of infection by Ascaris suum, by in vitro production of nitrite using the Griess reagent and cell viability by
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43

Miradouro, Cristina Maria Nunes de Carvalho. "Serviço de segurança alimentar executado pelo médico veterinário." Master's thesis, Universidade de Évora, 2015. http://hdl.handle.net/10174/17655.

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No presente trabalho, fez-se uma breve descrição das situações observadas durante o acompanhamento das equipas de inspecção sanitária do estabelecimento de abate, de subprodutos de origem animal, dos produtos de pesca e das unidades de produção primária de leite, de acordo com o suporte legal que regula esta atividade. Deu-se especial destaque à inspeção sanitária de suínos, uma vez que se tratou da principal espécie animal inspecionada neste período de tempo. Neste contexto, abordaram-se alguns temas importantes como a Informação Relativa à Cadeia Alimentar, a inspeção ante-mortem, o bem-esta
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44

Nignan, Alexis. "Isolement, purification et étude immunologique d'un antigène d'"Ascaris suum" : application au diagnostic immunologique de l'onchocercose humaine." Paris 5, 1989. http://www.theses.fr/1989PA05P502.

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45

Ghosh, Paritosh. "De Novo Glycogen Biosynthesis by a Glycogen Primer Complex in the Obliquely Striated Skeletal Muscle of Ascaris suum." Thesis, North Texas State University, 1987. https://digital.library.unt.edu/ark:/67531/metadc935639/.

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During the purification of the enzyme glycogen synthase from the muscle of the nematode Ascaris suum, approximately 70% of the glycogen synthase activity can be separated from the bulk of cellular glycogen by centrifugation for 60 min at 105,000 x . The glycogen synthase in the supernatant fraction has an Mr of 1.2 x 106 as determined by Sepharose 4B gel filtration chromatography. The glycogen synthase in this high molecular weight complex (glycogen primer complex) can be further purified by ConA-Sepharose affinity chromatography; the enzyme activity was eluted with 100 .mM a-methylmannoside.
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46

Bush, Elizabeth Rosina. "Molecular biology and expression of some ligand-gated ion channels from the nematodes Ascaris suum and Caenorhabditis elegans." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246225.

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47

Shahkolahi, Akbar Mohammadpour. "Physiological Effects of Ascaris Suum Intestinal Microflora on 5-Hydroxytryptamine Level and Binding Sites in the Intestinal Epithelial Cells." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc277786/.

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Serotonin (5-hydroxytryptamine, 5-HT) has been shown to activate carbohydrate metabolism in adult female Ascaris suum. Serotonin may be either absorbed directly from the environment or synthesized de novo from the absorbed L-tryptophan in adult female A. suum. The enzymes necessary for the synthesis of 5-HT have been identified in both intestine and muscle tissues. The serotonin absorbed from the environment is obtained either from the host's gastrointestinal contents or from the 5-HT producing bacteria in the intestine of A. suum. Numerous 5-HT producing bacteria were identified in the intest
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48

NASCIMENTO, Wheverton Ricardo Correia do. "Estudo a ação imunorregulatória do extrato solúvel de Ascaris Suum sobre a injúria hepática experimental mediada por células imunes." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/18506.

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Submitted by Caroline Falcao (caroline.rfalcao@ufpe.br) on 2017-04-06T17:10:41Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-dissertação-WhevertonRicardoCorreiaNascimento.pdf: 4035736 bytes, checksum: f33cf235cb56b67d16c3e819dbebb2a1 (MD5)<br>Made available in DSpace on 2017-04-06T17:10:41Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) 2012-dissertação-WhevertonRicardoCorreiaNascimento.pdf: 4035736 bytes, checksum: f33cf235cb56b67d16c3e819dbebb2a1 (MD5) Previous issue date: 2012-03-
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49

Favoretto, Bruna Cristina. "Avaliação da participação dos receptores do tipo Toll e lectinas tipo C na supressão da resposta imune induzida por componentes de alta massa molecular do extrato de Ascaris suum." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-11082010-141157/.

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Helmintos e seus produtos são potentes moduladores da resposta imune. Componentes de alta massa molecular do extrato de Ascaris suum (PI) suprimem a resposta anti-ovalbumina. Nas células apresentadoras de antígeno (APCs) como as dendríticas (DCs) os componentes do PI inibem a expressão de moléculas MHC-II e coestimuladoras e, assim a ativação de linfócitos TCD4+. Receptores de membrana de APCs como os do tipo Toll (TLRs) e lectina tipo-C (CLRs) reconhecem padrões moleculares de patógenos e modulam a resposta imune efetora. Assim sendo, foi estudada o papel de TLRs e CLRs expressos nas APCs na
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50

Robertson, Alan P. "A patch-clamp study of-ion channels in membrane vesicles prepared from the parasitic helminths Ascaris suum and Schistosoma mansoni." Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/29966.

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Membrane vesicles prepared from the bag region of the somatic muscle cells of the parasitic nematode <I>Ascaris suum </I>(a close relative of <I>A. lumbricoides</I>) contain high-conductance, voltage-sensitive, Ca-dependent chloride channels. The effect of altered pH on this channel was investigated using the patch-clamp technique and isolated inside-out membrane patches. Changes in pH had little effect on channel conductances and reversal potentials. Under control conditions (symmetrical pH 7.2) the channel had the highest probability of opening at ˜-35mV (the resting membrane potential of th
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