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Journal articles on the topic 'Asd7'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Li, Yingying, Wei Wang, Na Zhang, et al. "Antagonistic Regulation of ABA Responses by Duplicated Tandemly Repeated DUF538 Protein Genes in Arabidopsis." Plants 12, no. 16 (2023): 2989. http://dx.doi.org/10.3390/plants12162989.

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The plant hormone ABA (abscisic acid) regulates plant responses to abiotic stresses by regulating the expression of ABA response genes. However, the functions of a large portion of ABA response genes have remained unclear. We report in this study the identification of ASDs (ABA-inducible signal peptide-containing DUF538 proteins), a subgroup of DUF538 proteins with a signal peptide, as the regulators of plant responses to ABA in Arabidopsis. ASDs are encoded by four closely related DUF538 genes, with ASD1/ASD2 and ASD3/ASD4 being two pairs of duplicated tandemly repeated genes. The quantitativ

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Chaerani, Ahmad Dadang, Sutrisno, Bahagiawati, and Muhamad Yunus. "Virulence and SSR Diversity of Brown Planthopper (Nilaparvata lugens) Adapted on Differential Rice Host Varieties." HAYATI Journal of Biosciences 28, no. 4 (2021): 293–303. http://dx.doi.org/10.4308/hjb.28.4.293-303.

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Brown planthopper biotype 1, 2, 3 and a representative field population are required for resistance screening of promising rice lines in Indonesia, but the current biotype stocks has shown deviation in virulence patterns. The objectives of this study were to develop a set of brown planthopper populations with differential virulence and to investigate their genetic variability using SSR marker. Females originated from two field populations were selected on variety Mudgo (carries Bph1 gene) or ASD7 (bph2 gene) using honeydew excretion as the virulence parameter. Selection cycles resulted in popu

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Gong, Gu, Yu-Dan Zhang, Zhen-Fei Zhang, and Wei-Jian Wu. "Alternately Rearing with Susceptible Variety Can Delay the Virulence Development of Insect Pests to Resistant Varieties." Agriculture 12, no. 7 (2022): 991. http://dx.doi.org/10.3390/agriculture12070991.

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Resistant crop varieties can usually decrease the population density of insect pests; however, they can also easily cause the occurrence of highly virulent pest populations when repeatedly grown. Whether herbivorous insects feeding intermittently on a susceptible variety affects their subsequent virulence has rarely been investigated. In this paper, we examined the variations in the virulence of the brown planthopper (BPH), Nilaparvata lugens (Stål) (Hemiptera: Delphacidae), by alternately rearing three resistant rice varieties, Mudgo, ASD7, and Rathu Heenati, with a susceptible rice variety (

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Zvereva, N., N. Simashkova, and A. Koval-Zaitsev. "Comparison of cognitive functions children with the autism spectrum disorders and schizophrenia." European Psychiatry 41, S1 (2017): S457—S458. http://dx.doi.org/10.1016/j.eurpsy.2017.01.498.

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IntroductionAutism spectrum disorder and early onset schizophrenia have many similar symptoms, however, these are different disorders. It is important to identify the main similarities\differences in the structure of cognitive impairment to define further assistance these children correctly. We distinguished two options for cognitive defect (total and partial) in children with schizophrenia.AimsComparison of cognitive functions at children with autism spectrum disorder and early onset schizophrenia.ObjectivesTwo groups with autism spectrum disorder (ASD1 – 22 patients of MHRC mean age 8.9; ASD

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Kamandi, Neda. "Adjacent Segment Degeneration and Adjacent Segment Disease: Implications following Spinal Fusion Surgery." SVOA Neurology 5, no. 2 (2024): 68–72. http://dx.doi.org/10.58624/svoane.2024.05.0130.

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Spinal fusion is a common and effective option for patients with symptomatic degenerative disc disorders. However, concerns have raised over the probability of adjacent segment degeneration (ASDe) and adjacent segment disease (ASDi) following spinal instrumentation. Current study sought to document evidence on the incidence of ASDe and ASDi after lumbar fusion surgery and the risk factors precipitating adjacent pathologies. Given the benefits of spinal fusion surgery, it remains unclear whether adjacent pathologies are attributed to the natural degeneration or the adjacent fusion.

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Kurniawati, Sri, Pepi Nur Susilawati, Yuti Giamerti, et al. "Identification of the resistance of local Banten rice to biotype 2 brown planthoppers (Nilaparvata lugens stål.)." BIO Web of Conferences 158 (2025): 03022. https://doi.org/10.1051/bioconf/202515803022.

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The brown planthopper (BPH) is one of the major pests of rice that causes significant losses. One of the control efforts against BPH is using resistant varieties. Local rice varieties serve as germplasm resources that can be utilized to develop resistant varieties. This research aims to identify the resistance of four local rice varieties from Banten to BPH and to identify the biotype of the tested BPH insect used in this study. The study was conducted from November 2018 to April 2019 at the greenhouse of the Banten Assessment Institute for Agricultural Technology. Resistance identification ag

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Lai, Chengling, Yun Hou, Peiying Hao, Kun Pang, and Xiaoping Yu. "Detection of Yeast-like Symbionts in Brown Planthopper Reared on Different Resistant Rice Varieties Combining DGGE and Absolute Quantitative Real-Time PCR." Insects 13, no. 1 (2022): 85. http://dx.doi.org/10.3390/insects13010085.

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The brown planthopper (BPH), Nilaparvata lugens, is a serious pest of rice throughout Asia. Yeast-like symbionts (YLS) are endosymbionts closely linked with the development of BPH and the adapted mechanism of BPH virulence to resistant plants. In this study, we used semi-quantitative DGGE and absolute quantitative real-time PCR (qPCR) to quantify the number of the three YLS strains (Ascomycetes symbionts, Pichia-like symbionts, and Candida-like symbionts) that typically infect BPH in the nymphal stages and in newly emerged female adults. The quantities of each of the three YLS assessed increas

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Alhamhoom, Yahya, Thanusha Kumaraswamy, Avichal Kumar, et al. "Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir." Pharmaceutics 16, no. 7 (2024): 866. http://dx.doi.org/10.3390/pharmaceutics16070866.

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Cefdinir (CEF) is a semi-synthetic third-generation broad-spectrum oral cephalosporin that exhibits poor solubility at lower pH values. Considering this, pH-modulated CEF solid dispersions (ASDs) were produced by solvent evaporation method employing various hydrophilic carriers and alkalizers. Among different carriers, ASDs produced using PEG 6000 with meglumine as alkalizer were found to significantly increase (p < 0.005) the drug solubility (4.50 ± 0.32 mg/mL) in pH 1.2. Fourier transform infrared spectrophotometry confirmed chemical integrity of CEF while differential scanning calorimetr

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Tang, Ming, Lu Lv, Shengli Jing, Lili Zhu, and Guangcun He. "Bacterial Symbionts of the Brown Planthopper, Nilaparvata lugens (Homoptera: Delphacidae)." Applied and Environmental Microbiology 76, no. 6 (2010): 1740–45. http://dx.doi.org/10.1128/aem.02240-09.

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ABSTRACT The brown planthopper (Nilaparvata lugens Stål), the most destructive pest of rice, has been identified, including biotypes with high virulence towards previously resistant rice varieties. There have also been many reports of a yeast-like symbiont of N. lugens, but little is known about the bacterial microbes. In this study, we examined the bacterial microbes in N. lugens and identified a total of 18 operational taxonomic units (OTUs) representing four phyla (Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes) by sequencing and analyzing 16S rRNA gene libraries obtained fr

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10

Thayumanavan, B. "Molecular Basis for Puffing Quality of Rice." International Rice Research Newsletter 12, no. 4 (1987): 10. https://doi.org/10.5281/zenodo.7122935.

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This article 'Molecular Basis for Puffing Quality of Rice' appeared in the International Rice Research Newsletter series, created by the International Rice Research Institute (IRRI). The primary objective of this publication was to expedite communication among scientists concerned with the development of improved technology for rice and for rice based cropping systems. This publication will report what scientists are doing to increase the production of rice in as much as this crop feeds the most densely populated and land scarce nations in the world.

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Chaerani, Chaerani, Siti Yuriyah, Ahmad Dadang, et al. "SSR MARKERS REVEALED GENETIC DIVERGENCE OF RICE BROWN PLANTHOPPER POPULATIONS MAINTAINED ON TWO SETS OF DIFFERENTIAL HOST VARIETIES." Indonesian Journal of Agricultural Science 22, no. 2 (2021): 77. http://dx.doi.org/10.21082/ijas.v22n2.2021.p77-84.

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<p>Resistance screening of promising rice lines in Indonesia requires the use of brown planthopper (BPH) biotypes 1, 2, and 3. Three BPH populations have been raised as biotypes 1, 2, and 3 on differential rice host of improved varieties Pelita I-1 (no <em>Bph </em>gene), IR26 (<em>Bph1</em>), and IR42 (<em>bph2</em>), respectively. Three alternative populations have also been developed on the respective traditional varieties TN1 (no <em>Bph </em>gene), Mudgo (<em>Bph1</em>), and ASD7 (<em>bph2</em>). Although these

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Di Gioia, Francesco, Monica Ozores-Hampton, Jason Hong, et al. "The Effects of Anaerobic Soil Disinfestation on Weed and Nematode Control, Fruit Yield, and Quality of Florida Fresh-market Tomato." HortScience 51, no. 6 (2016): 703–11. http://dx.doi.org/10.21273/hortsci.51.6.703.

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Anaerobic soil disinfestation (ASD) is considered a promising sustainable alternative to chemical soil fumigation (CSF), and has been shown to be effective against soilborne diseases, plant-parasitic nematodes, and weeds in several crop production systems. Nevertheless, limited information is available on the effects of ASD on crop yield and quality. Therefore, a field study was conducted on fresh-market tomato (Solanum lycopersicum L.) in two different locations in Florida (Immokalee and Citra), to evaluate and compare the ASD and CSF performances on weed and nematodes control, and on fruit y

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Chaerani, Chaerani, Diani Damayanti, Trisnaningsih Trisnaningsih, et al. "Virulence of Brown Planthopper and Development of Core Collection of the Pest." Jurnal Penelitian Pertanian Tanaman Pangan 35, no. 2 (2016): 109. http://dx.doi.org/10.21082/jpptp.v35n2.2016.p109-118.

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Brown planthopper is the most important rice pest in Indonesia. Its high adaptability to feed and reproduce on previously introduced resistant varieties to form more virulent population often causes BPH outbreak and hopperburn that lead to total crop yield loss. Rice breeding for resistant to BPH requires information on the current status of BPH virulences in the fields to anticipate the virulence adaptation on new varieties. The objectives of this study were to investigate the degree of virulence of BPH populations and to cluster the BPH virulence to form BPH core collection. Thirteen BPH pop

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Fukuda, Kazuhiko. "One Explanatory Basis for the Discrepancy of Reported Prevalences of Sleep Paralysis among Healthy Respondents." Perceptual and Motor Skills 77, no. 3 (1993): 803–7. http://dx.doi.org/10.2466/pms.1993.77.3.803.

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In a previous study, the author and coworkers found 39.8% of healthy young adults had experienced sleep paralysis. Some other studies reported prevalence as about the same or higher (i.e., 40.7% to 62.0%) than that previous estimate, while yet other studies, including Goode's work cited by ASDC and ASDA classifications, suggested much lower prevalences (i.e., 4.7% to 26.2%). The author tested the hypothesis that this discrepancy among the reported prevalences is partly due to the expression used in each questionnaire. University students who answered the questionnaire using the term ‘transient

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Cahyanto, Muhammad N., Hiroko Kawasaki, Mariko Nagashio, Kazuhito Fujiyama, and Tatsuji Seki. "Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum." Microbiology 152, no. 1 (2006): 105–12. http://dx.doi.org/10.1099/mic.0.28092-0.

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The use of a lysine-overproducing strain of Lactobacillus plantarum in food or feed fermentations may lead to the production of lysine-rich products. The availability of functional genes and information on the regulation of lysine biosynthesis are required to develop a lysine-overproducing strain. The genome sequence of L. plantarum revealed putative lysine biosynthetic genes, some of which may produce isozymes. This study examined the functionality of the genes and the regulation of the first four enzymes of lysine biosynthesis, together with homoserine dehydrogenase, in L. plantarum. The gen

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Van Mai, Tan, Daisuke Fujita, Masaya Matsumura, Atsushi Yoshimura, and Hideshi Yasui. "Genetic basis of multiple resistance to the brown planthopper (Nilaparvata lugens Stål) and the green rice leafhopper (Nephotettix cincticeps Uhler) in the rice cultivar ‘ASD7’ (Oryza sativa L. ssp. indica)." Breeding Science 65, no. 5 (2015): 420–29. http://dx.doi.org/10.1270/jsbbs.65.420.

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Li, Chao, Yi Lin, Wenmin Lv, and Jinhai Zhang. "Eliminating above-surface diffractions from ground-penetrating radar data using iterative Stolt migration." GEOPHYSICS 86, no. 1 (2021): H1—H11. http://dx.doi.org/10.1190/geo2019-0796.1.

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Above-surface diffractions (ASDs) received by unshielded ground-penetrating radar (GPR) antennas are known to contaminate subsurface reflections and diffractions. Existing ASD-removal methods either leave relatively strong residual ASDs within subsurface reflections or attenuate them excessively. We have developed an iterative migration-based ASD-removal method to address this issue that separates ASDs from subsurface reflections via surgical mute. First, we isolate ASDs within the GPR profile using an optimal window function, generated using the focal center of ASDs within the migrated domain

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Grzadzinski, Rebecca, Marisela Huerta, and Catherine Lord. "DSM-5 and autism spectrum disorders (ASDs): an opportunity for identifying ASD subtypes." Molecular Autism 4, no. 1 (2013): 12. http://dx.doi.org/10.1186/2040-2392-4-12.

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Prashanth Parupathi and Siddharatha Dhoppalapudi. "Downstream processing of amorphous solid dispersions into tablets." GSC Biological and Pharmaceutical Sciences 22, no. 1 (2023): 170–77. http://dx.doi.org/10.30574/gscbps.2023.22.1.0013.

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Amorphous solid dispersions have gained tremendous attention as a commercially viable solubility enhancement technique for poorly water-soluble drugs. However, poor drug loading associated with poor drug-polymer miscibility is a major challenge in the downstream processing of ASDs. While many downstream techniques are available for converting ASDs into final dosage forms, oral solids remain the most commercially viable. The type of excipients used in the conversion of ASDs into tablets are very similar to the excipients used in conventional tablets. For example, the binders used in conventiona

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Prashanth, Parupathi, and Dhoppalapudi Siddharatha. "Downstream processing of amorphous solid dispersions into tablets." GSC Biological and Pharmaceutical Sciences 22, no. 1 (2023): 170–77. https://doi.org/10.5281/zenodo.7661261.

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Amorphous solid dispersions have gained tremendous attention as a commercially viable solubility enhancement technique for poorly water-soluble drugs. However, poor drug loading associated with poor drug-polymer miscibility is a major challenge in the downstream processing of ASDs. While many downstream techniques are available for converting ASDs into final dosage forms, oral solids remain the most commercially viable. The type of excipients used in the conversion of ASDs into tablets are very similar to the excipients used in conventional tablets. For example, the binders used in conventiona

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Carpentier, Stefan F., Heinrich Horstmeyer, Alan G. Green, Joseph Doetsch, and Ilaria Coscia. "Semiautomated suppression of above-surface diffractions in GPR data." GEOPHYSICS 75, no. 6 (2010): J43—J50. http://dx.doi.org/10.1190/1.3497360.

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Diffractions from above-surface objects can be a major problem in the processing and interpretation of ground-penetrating radar (GPR) data. Whereas methods to reduce random and many other types of source-generated noise are available, the efficient suppression of above-surface diffractions (ASDs) continues to be challenging. We have developed a scheme for semiautomatically detecting and suppressing ASDs. Initially, an accurate representation of ASDs is obtained by (1) Stolt [Formula: see text] migrating the GPR data using the air velocity to focus ASDs, (2) multichannel filtering to minimize o

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Tambe, Srushti, Divya Jain, Sai Kishore Meruva, et al. "Recent Advances in Amorphous Solid Dispersions: Preformulation, Formulation Strategies, Technological Advancements and Characterization." Pharmaceutics 14, no. 10 (2022): 2203. http://dx.doi.org/10.3390/pharmaceutics14102203.

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Amorphous solid dispersions (ASDs) are among the most popular and widely studied solubility enhancement techniques. Since their inception in the early 1960s, the formulation development of ASDs has undergone tremendous progress. For instance, the method of preparing ASDs evolved from solvent-based approaches to solvent-free methods such as hot melt extrusion and Kinetisol®. The formulation approaches have advanced from employing a single polymeric carrier to multiple carriers with plasticizers to improve the stability and performance of ASDs. Major excipient manufacturers recognized the potent

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Othman, Norashiken, Ummi Noor Nazahiah Abdullah, Nazmin Abdullah, Gogulasanti K Ganesan, and Roshidi Bakar@Samad. "Gender Equality in ASDC: Unravelling Societal Challenge in Educational Attainment and Economic Empowerment, Inheritance Access, and Workplace Dynamics in Malaysia." International Conference on Gender Research 7, no. 1 (2024): 293–302. http://dx.doi.org/10.34190/icgr.7.1.2286.

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This study investigates the nuanced intersectionality of gender equality within the context of Autism Spectrum Disorder Condition (ASDC) individuals. Contrary to Feminism, which advocates for gender equality and women's rights. While existing research has predominantly focused on the clinical aspects of ASDC, this study delves into the educational attainment and economic empowerment, inheritance access and workplace dynamics that impact individuals with ASDC, with a particular emphasis on gender-related disparities. The research encompasses ASDC in-depth analysis of access to resources, includ

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Foti, F., F. De Crescenzo, G. Vivanti, D. Menghini, and S. Vicari. "Implicit learning in individuals with autism spectrum disorders: a meta-analysis." Psychological Medicine 45, no. 5 (2014): 897–910. http://dx.doi.org/10.1017/s0033291714001950.

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Background.Individuals with autism spectrum disorders (ASDs) are characterized by social communication difficulties and behavioural rigidity. Difficulties in learning from others are one of the most devastating features of this group of conditions. Nevertheless, the nature of learning difficulties in ASDs is still unclear. Given the relevance of implicit learning for social and communicative functioning, a link has been hypothesized between ASDs and implicit learning deficit. However, studies that have employed formal testing of implicit learning in ASDs provided mixed results.Method.We undert

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Shi, Shenglong, Jinsheng Sun, Kaihe Lv, et al. "Fracturing Fluid Polymer Thickener with Superior Temperature, Salt and Shear Resistance Properties from the Synergistic Effect of Double-Tail Hydrophobic Monomer and Nonionic Polymerizable Surfactant." Molecules 28, no. 13 (2023): 5104. http://dx.doi.org/10.3390/molecules28135104.

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To develop high-salinity, high-temperature reservoirs, two hydrophobically associating polymers as fracturing fluid thickener were respectively synthesized through aqueous solution polymerization with acrylamide (AM), acrylic acid (AA), 2-acrylamido-2-methylpropanesulfonic acid (AMPS), nonionic polymerizable surfactant (NPS) and double-tail hydrophobic monomer (DHM). The thickener ASDM (AM/AA/AMPS/NPS/DHM) and thickener ASD (AM/AA/AMPS/DHM) were compared in terms of properties of water dissolution, thickening ability, rheological behavior and sand-carrying. The results showed that ASDM could b

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Chirdkiatgumchai, Vilawan, Nichara Ruangdaraganon, Rawiwan Roongpraiwan, Tasnawat Sombuntham, Pat Rojmahamongkol, and Rungtip Prasertchai. "Thai parental perception of the etiology of autism spectrum disorders with an emphasis on genetics." Asian Biomedicine 4, no. 5 (2010): 773–79. http://dx.doi.org/10.2478/abm-2010-0100.

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Abstract Background: More than 90% of cases of autism spectrum disorders (ASDs) are idiopathic and are multi-factorial inheritant in etiology. Although parental perceptions of ASDs etiologies including genetics have been investigated well in western countries, there is no study regarding Asian parental perspectives on the genetic etiology of ASDs. Objectives: Examine what Thai parents perceived to be the etiology of ASDs with particular focus on the role of genetics, and analyze the correlation between demographics of parents and the perception of genetics as an etiology of ASDs. Methods: Chil

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Higashijima, Jin, Yui Miura, Chie Nakagawa, Yasunori Yamanouchi, Kae Takahashi, and Masaki Nakamura. "Public opinions regarding the relationship between Autism Spectrum Disorders and society: social agenda construction via science café and public dialogue using questionnaires." Journal of Science Communication 11, no. 04 (2012): A03. http://dx.doi.org/10.22323/2.11040203.

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Rapid and significant developments in the science of Autism Spectrum Disorders (ASDs) have provoked serious social and ethical concerns as well as positive influences worldwide. This study created a social agenda containing 21 important issues regarding the relationship between ASDs and society and the development of the science of ASDs. The agenda was constructed with the input of a variety of Japanese people who were provided with scientific ASD information and engaged in discussions regarding ASDs. First, opinions were sought via a questionnaire from the attendees of six science café sessio

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Siddharatha Dhoppalapudi. "Considerations in the formulation of amorphous solid dispersions by hot melt extrusion." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 012–21. http://dx.doi.org/10.30574/gscbps.2022.21.2.0421.

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Hot melt extrusion is one of the most popular techniques for the manufacturing of amorphous solid dispersions (ASDs). Over few decades, it has transitioned from lab scale to commercial scale with various products in the market. The current review aims at summarizing various considerations in the formulation development of ASDs using HME. Various types of ASDs from Type I to Type IV are discussed along with the solid state of drug and polymeric carrier in each type. Also, various polymeric carriers used in ASDs are outlined along with information about their glass transition temperature, meltin

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Siddharatha, Dhoppalapudi. "Considerations in the formulation of amorphous solid dispersions by hot melt extrusion." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 012–21. https://doi.org/10.5281/zenodo.7650218.

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Hot melt extrusion is one of the most popular techniques for the manufacturing of amorphous solid dispersions (ASDs). Over few decades, it has transitioned from lab scale to commercial scale with various products in the market. The current review aims at summarizing various considerations in the formulation development of ASDs using HME. Various types of ASDs from Type I to Type IV are discussed along with the solid state of drug and polymeric carrier in each type. Also, various polymeric carriers used in ASDs are outlined along with information about their glass transition temperature, meltin

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Tubtimsri, Sukannika, and Yotsanan Weerapol. "Development of Nifedipine Amorphous Solid Dispersion Composed of Surface-Active Agents." Key Engineering Materials 901 (October 8, 2021): 35–39. http://dx.doi.org/10.4028/www.scientific.net/kem.901.35.

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The amorphous solid dispersions (ASDs) containing amino methacrylate copolymer and surface-active agents were prepared to improve the nifedipine (NDP) dissolution. The different types of surface-active agent i.e., polysorbates 80, sodium lauryl sulfate (SLS) and polyethylene glycol (PEG) 400 were used. In order to evaluate the ASDs formulation,powder X-ray diffractometry and thermal analysis to characterize NDP crystallinity in ASDs and the dissolution study of NDP have been performed to compare the dissolution profiles. The ASDs were kept for 6 months to investigate the stability. In the X-ra

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Biesbroek, J. Matthijs, Gabriel J. E. Rinkel, Ale Algra, and Jan Willem Berkelbach van der Sprenkel. "Risk Factors for Acute Subdural Hematoma From Intracranial Aneurysm Rupture." Neurosurgery 71, no. 2 (2012): 264–69. http://dx.doi.org/10.1227/neu.0b013e318256c27d.

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Abstract BACKGROUND: An acute subdural hematoma (aSDH) is a rare complication of aneurysmal subarachnoid hemorrhage (SAH) and is associated with poor clinical condition on admission and poor outcome. Risk factors for the development of an aSDH from aneurysmal rupture are unknown and may help our understanding of how an aSDH develops. OBJECTIVE: To identify risk factors for the development of an aSDH from intracranial aneurysm rupture. METHODS: Patients were selected from our prospectively collected single-center SAH database. From all 1757 patients fulfilling prespecified inclusion criteria, 6

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Świątkiewicz, Iwona, Łukasz Bednarczyk, Michał Kasprzak, Ewa Laskowska, and Marek Woźnicki. "Effectiveness and Safety of Transcatheter Atrial Septal Defect Closure in Adults with Systemic Essential Hypertension." Journal of Clinical Medicine 11, no. 4 (2022): 973. http://dx.doi.org/10.3390/jcm11040973.

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Concomitant systemic essential hypertension (HTN) in adults with a secundum atrial septal defect (ASD) can unfavorably affect the hemodynamics and transcatheter ASD closure (ASDC) effects. This study aims to assess the effectiveness and safety of ASDC in adults with HTN in real-world clinical practice. Right ventricular (RV) reverse remodeling (RVR) and the lack of a left-to-right interatrial residual shunt (NoRS) in echocardiography 24 h and 6 months (6 M) post-ASDC, and ASDC-related complications within 6 M were evaluated in 184 adults: 79 with HTN (HTN+) and 105 without HTN (HTN−). Compared

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Rahman, Mahbubur, Stephanie Ahmad, James Tarabokija, Nathaniel Parker, and Ecevit Bilgili. "Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component." Pharmaceutics 12, no. 3 (2020): 197. http://dx.doi.org/10.3390/pharmaceutics12030197.

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This study aimed to elucidate the impact of a common anionic surfactant, sodium dodecyl sulfate (SDS), along with hydroxypropyl cellulose (HPC) and Soluplus (Sol) on the release of griseofulvin (GF), a poorly soluble drug, from amorphous solid dispersions (ASDs). Solutions of 2.5% GF and 2.5%–12.5% HPC/Sol with 0.125% SDS/without SDS were prepared in acetone–water and spray-dried. The solid-state characterization of the ASDs suggests that GF–Sol had better miscibility and stronger interactions than GF–HPC and formed XRPD-amorphous GF, whereas HPC-based ASDs, especially the ones with a lower HP

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Ousley, O. Y., E. Smearman, S. Fernandez-Carriba, et al. "Axis I psychiatric diagnoses in adolescents and young adults with 22q11 deletion syndrome." European Psychiatry 28, no. 7 (2013): 417–22. http://dx.doi.org/10.1016/j.eurpsy.2013.06.002.

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AbstractBackground22q11.2 deletion syndrome (22q11DS) associates with schizophrenia spectrum disorders (SSDs), autism spectrum disorders (ASDs), and other psychiatric disorders, but co-occurrence of diagnoses are not well described.MethodsWe evaluated the co-occurrence of SSDs, ASDs and other axis I psychiatric diagnoses in 31 adolescents and adults with 22q11DS, assessing ASDs using either stringent Collaborative Program for Excellence in Autism (ASD-CPEA) criteria, or less stringent DSM-IV criteria alone (ASD-DSM-IV).ResultsTen (32%) individuals met criteria for an SSD, five (16%) for ASD-CP

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Baxter, A. J., T. S. Brugha, H. E. Erskine, R. W. Scheurer, T. Vos, and J. G. Scott. "The epidemiology and global burden of autism spectrum disorders." Psychological Medicine 45, no. 3 (2014): 601–13. http://dx.doi.org/10.1017/s003329171400172x.

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BackgroundAutism spectrum disorders (ASDs) are persistent disabling neurodevelopmental disorders clinically evident from early childhood. For the first time, the burden of ASDs has been estimated for the Global Burden of Disease Study 2010 (GBD 2010). The aims of this study were to develop global and regional prevalence models and estimate the global burden of disease of ASDs.MethodA systematic review was conducted for epidemiological data (prevalence, incidence, remission and mortality risk) of autistic disorder and other ASDs. Data were pooled using a Bayesian meta-regression approach while

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Burt, Steve, and Leigh Sparks. "The Implications of Wal-Mart's Takeover of ASDA." Environment and Planning A: Economy and Space 33, no. 8 (2001): 1463–87. http://dx.doi.org/10.1068/a33219.

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Wal-Mart is the world's largest retailer. Within the United Kingdom, retailing has generally been considered as a local or national activity. Wal-Mart's purchase of ASDA in 1999 illustrates the global scale of much modern retailing. In this paper we consider the implications of Wal-Mart's takeover of ASDA. First, the key drivers of Wal-Mart's business success are analysed. Second, the impact of Wal-Mart in Canada and Germany is considered. Third, the match of Wal-Mart with ASDA is examined. Fourth, the key changes Wal-Mart is making to ASDA are reviewed. This consideration of Wal-Mart and ASDA

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Wang, Huan-Chih, Jui-Chang Tsai, Jing-Er Lee, et al. "Direct visualization of microcirculation impairment after acute subdural hemorrhage in a novel animal model." Journal of Neurosurgery 129, no. 4 (2018): 997–1007. http://dx.doi.org/10.3171/2017.5.jns162579.

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OBJECTIVEDirect brain compression and secondary injury due to increased intracranial pressure are believed to be the pathognomic causes of a grave outcome in acute subdural hemorrhage (aSDH). However, ischemic damage from aSDH has received limited attention. The authors hypothesized that cerebral microcirculation is altered after aSDH. Direct visualization of microcirculation was conducted in a novel rat model.METHODSA craniectomy was performed on each of the 18 experimental adult Wistar rats, followed by superfusion of autologous arterial blood onto the cortical surface. Changes in microcircu

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Zheng, Wenling, Junni Ke, Kaerdun Liu, Rongrong Xue, and Fenghua Chen. "Aqueous Solution Spray Drying Preparations of Binary Amorphous Solid Dispersions." Crystals 15, no. 4 (2025): 323. https://doi.org/10.3390/cryst15040323.

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Spray drying of poorly water-soluble drugs in organic solvents is a mature process in the preparation of drugs amorphous solids dispersions (ASDs). The use of organic solvents is under increasing environmental protection and safety pressure and restricts the application of advanced polymers as proteins which are usually insoluble and unstable in organic solvents. Aqueous solution spray drying technology is a candidate method for preparing ASDs without the use of organic solvents. Increasing temperature and adding volatile additives can improve the solubility of poorly water-soluble drugs in wa

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Jain, Raunak, Crystallynn Skye The, Mary M. Murphy, and Anand S. Pandit. "Surgical significance of prolonged fixed and dilated pupils in a case of non-traumatic, spontaneously regressing, acute subdural haemorrhage." BMJ Case Reports 15, no. 4 (2022): e247388. http://dx.doi.org/10.1136/bcr-2021-247388.

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Bilaterally fixed and dilated pupils (BFDP) in traumatic acute subdural haematoma (ASDH) patients represent an ominous sign that portends irreversible brainstem injury and death. Whether patients with spontaneous ASDH and BFDP follow similar outcomes is unknown. We present a mid-60s man, found unconscious, with a Glasgow Coma Scale (GCS) of 4 following 8 days of headaches. Emergency CT imaging demonstrated a large right ASDH and the patient exhibited BFDP for >3 hours despite sedation and mannitol. Neurological improvement and spontaneously reduced SDH thickness were observed 10 hours posta

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Jelínková, Beáta. "Potential of ICT in Teaching English as a Foreign Language Focused on Autistic Spectrum Learners." SHS Web of Conferences 88 (2020): 02012. http://dx.doi.org/10.1051/shsconf/20208802012.

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The number of children with Autistic Spectrum Disorders (ASDs) educated under mainstream school system is still raising. Since English is a compulsory subject for every school child in Slovakia, students with ASDs also belong to the group of English language learners. Thereupon causing worries to teachers and calling for a necessity of a wider concept. The purpose of the study is to help the ASDs learners and their teachers to acquire the curriculum under the virtue of ICT. Data were collected via the Case Study as the main research, based on teacher´s daily experience in teaching English to A

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Budi, Luh Putu Rihayani, Mei Neni Sitaresmi, and I. Gusti Ayu Trisna Windiani. "Paternal and maternal age at pregnancy and autism spectrum disorders in offspring." Paediatrica Indonesiana 55, no. 6 (2016): 345. http://dx.doi.org/10.14238/pi55.6.2015.345-51.

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Background The prevalence of autism spectrum disorders(ASDs) has increased 10 times over the past half century,while paternal and maternal age at pregnancy has alsoincreased. Studies looking for an association between paternalor maternal age at pregnancy and ASDs in offspring have notbeen conclusive.Objective To assess for possible associations between paternaland maternal age at pregnancy and ASDs in offspring.Methods This case-control study had 50 case and 100control subjects, each case was matched for age and genderto two controls. Case subjects were obtained by consecutivesampling of patie

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Lee, Brice Tseen Fu, and Juan Pablo Sims. "Redefining Regional Development: The Case for an ASEAN Development Bank." Journal of Political Issues 6, no. 1 (2024): 1–19. http://dx.doi.org/10.33019/jpi.v6i1.160.

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Amidst ASEAN's vibrant economic expansion lies an urgent need for a specialized financial institution—an ASEAN Development Bank (ASDB)—to harness and guide this growth. The region's dynamic diversity in development stages presents a unique opportunity for the ASDB to act as the catalyst for economic resilience and regional integration. This urgency is underscored by the potential for the ASDB to provide targeted financial strategies, directly addressing the specific challenges faced by member states. A robust and equitable governance structure will be crucial for the ASDB to facilitate strateg

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Rao, P. Syamasundar. "Role of Echocardiography in the Diagnosis and Interventional Management of Atrial Septal Defects." Diagnostics 12, no. 6 (2022): 1494. http://dx.doi.org/10.3390/diagnostics12061494.

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This review centers on the usefulness of echo-Doppler studies in the diagnosis of ostium secundum atrial septal defects (ASDs) and in their management, both in children and adults. Transthoracic echocardiography can easily identify the secundum ASDs and also differentiate secundum ASDs from other kinds of ASDs, such as ostium primum ASD, sinus venosus ASD and coronary sinus ASD, as well as patent foramen ovale. Preliminary selection of patients for device occlusion can be made by transthoracic echocardiograms while final selection is based on transesophageal (TEE) or intracardiac (ICE) echocar

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Fahad Bahaidarah, Afnan Adel Ashqa, Al Khonaizi, et al. "Acute Subdural Hematoma Management in the Emergency Department." Journal of Advanced Zoology 44, S6 (2023): 1247–52. http://dx.doi.org/10.17762/jaz.v44is6.2428.

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Acute subdural hematoma (ASDH) is a serious and potentially life-threatening condition that requires prompt and effective management in the emergency department (ED). This review article aims to provide an overview of the current evidence-based management strategies for ASDH in the ED setting. The article begins by discussing the pathophysiology of ASDH, emphasizing the rapid accumulation of blood between the dura mater and the arachnoid membrane following a traumatic brain injury. This can lead to increased intracranial pressure and potentially fatal brain herniation if not promptly addressed

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Monschke, Marius, and Karl G. Wagner. "Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions." Pharmaceutics 12, no. 6 (2020): 541. http://dx.doi.org/10.3390/pharmaceutics12060541.

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Amorphous solid dispersions (ASDs) have been proven to increase the bioavailability of poorly soluble drugs. It is desirable that the ASD provide a rapid dissolution rate and a sufficient stabilization of the generated supersaturation. In many cases, one polymer alone is not able to provide both features, which raises a need for reasonable polymer combinations. In this study we aimed to generate a rapidly dissolving ASD using the hydrophilic polymer polyvinyl alcohol (PVA) combined with a suitable precipitation inhibitor. Initially, PVA and hydroxypropylmethylcellulose acetate succinate (HPMCA

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Butera, Gianfranco, Nicusor Lovin, Domenica Paola Basile, and Mario Carminati. "Goose-neck snare-assisted transcatheter ASD closure: A safety procedure for large and complex ASDs." Catheterization and Cardiovascular Interventions 87, no. 5 (2016): 926–30. http://dx.doi.org/10.1002/ccd.26369.

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Neuwirth, Marius, Sebastian K. Kappes, Michael U. Hartig, and Karl G. Wagner. "Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?" Pharmaceutics 15, no. 3 (2023): 764. http://dx.doi.org/10.3390/pharmaceutics15030764.

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Spray drying is one of the most frequently used solvent-based processes for manufacturing amorphous solid dispersions (ASDs). However, the resulting fine powders usually require further downstream processing when intended for solid oral dosage forms. In this study, we compare properties and performance of spray-dried ASDs with ASDs coated onto neutral starter pellets in mini-scale. We successfully prepared binary ASDs with a drug load of 20% Ketoconazole (KCZ) or Loratadine (LRD) as weakly basic model drugs and hydroxypropyl-methyl-cellulose acetate succinate or methacrylic acid ethacrylate co

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Abdel-Khalek, Ahmed M., and Yagoub Al-Kandari. "Death Anxiety in Kuwaiti Middle-Aged Personnel." OMEGA - Journal of Death and Dying 55, no. 4 (2007): 297–310. http://dx.doi.org/10.2190/om.55.4.d.

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The present study aimed to examine the level of death anxiety, the sex-related differences among a middle-aged Kuwaiti personnel sample, and to explore the replicability of the Arabic Scale of Death Anxiety (ASDA) factors. A sample of 236 volunteer Kuwaiti personnel took part in the study. The mean ages of men and women were 41.5 ( SD = 7.5) and 40.9 ( SD = 7.1), respectively. The alpha reliability of the ASDA was found to be high (.93). Women had a significantly higher mean total score on the ASDA as well as on 17 out of its 20 items. Middle-aged personnel had a significantly lower mean ASDA

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Di Nanni, Noemi, Matteo Bersanelli, Francesca Anna Cupaioli, Luciano Milanesi, Alessandra Mezzelani, and Ettore Mosca. "Network-Based Integrative Analysis of Genomics, Epigenomics and Transcriptomics in Autism Spectrum Disorders." International Journal of Molecular Sciences 20, no. 13 (2019): 3363. http://dx.doi.org/10.3390/ijms20133363.

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Current studies suggest that autism spectrum disorders (ASDs) may be caused by many genetic factors. In fact, collectively considering multiple studies aimed at characterizing the basic pathophysiology of ASDs, a large number of genes has been proposed. Addressing the problem of molecular data interpretation using gene networks helps to explain genetic heterogeneity in terms of shared pathways. Besides, the integrative analysis of multiple omics has emerged as an approach to provide a more comprehensive view of a disease. In this work, we carry out a network-based meta-analysis of the genes re

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Fan, Shixin, Wenling Zheng, Shizhao Ren, Wangchuan Xiao, Fenghua Chen, and Rongrong Xue. "Boundary Between Amorphously and Molecularly Dispersed Curcumin of Its Amorphous Solid Dispersions Determined by Fluorescence Spectroscopy." Crystals 15, no. 6 (2025): 512. https://doi.org/10.3390/cryst15060512.

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Amorphous solid dispersion (ASD) technology is popularly used for enhancing the solubility of poorly water-soluble drugs. Drug molecules in ASDs can be dispersed in the form of either amorphous (AASD) or molecular (MASD) forms. The boundary between AASDs and MASDs (A–M boundary) is defined as the drug concentration at which the existence of MASDs obviously influences the physicochemical properties of ASDs. In this work, fluorescence spectroscopy based on the aggregation-caused quenching (ACQ) phenomenon was used to determine the A–M boundary of curcumin (CUR) ASDs prepared via neat ball millin

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