Academic literature on the topic 'Ashkenazi Jewish'

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Journal articles on the topic "Ashkenazi Jewish"

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Peretz, Hava, Avital Mulai, Sali Usher, Ariella Zivelin, Avihai Segal, Zahavi Weisman, Moshe Mittelman, et al. "The Two Common Mutations Causing Factor XI Deficiency in Jews Stem From Distinct Founders: One of Ancient Middle Eastern Origin and Another of More Recent European Origin." Blood 90, no. 7 (October 1, 1997): 2654–59. http://dx.doi.org/10.1182/blood.v90.7.2654.2654_2654_2659.

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Previous studies showed that factor XI (FXI) deficiency commonly observed in Ashkenazi Jews is caused by two similarly frequent mutations, type II (Glu117stop) and type III (Phe283Leu) with allele frequencies of 0.0217 and 0.0254, respectively. In Iraqi Jews, who represent the ancient gene pool of Jews, only the type II mutation was observed with an allele frequency of 0.0167. In this study we sought founder effects for each mutation by examination of four FXI gene polymorphisms enabling haplotype analysis in affected Jewish patients of Ashkenazi, Iraqi, and other origins and in Arab patients. Initial population surveys of 387 Middle Eastern Jews (excluding Iraqi Jews), 560 North African/Sephardic Jews, and 382 Arabs revealed allele frequencies for the type II mutation of 0.0026, 0.0027, and 0.0065, respectively. In contrast, the type III mutation was not detected in any of these populations. All 60 independent chromosomes bearing the type III mutation were solely observed in Ashkenazi Jewish patients and were characterized by a relatively rare haplotype. All 103 independent chromosomes bearing the type II mutation in patients of Ashkenazi, Iraqi, Yemenite, Syrian, and Moroccan Jewish origin and of Arab origin were characterized by another distinct haplotype that was rare among normal Ashkenazi Jewish, Iraqi Jewish, and Arab chromosomes. These findings constitute the first example of a mutation common to Ashkenazi Jews, non-Ashkenazi Jews, and Arabs and are consistent with the origin of type II mutation in a founder before the divergence of the major segments of Jews. Our findings also indicate that the type III mutation arose more recently in an Ashkenazi Jewish individual.
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Peretz, Hava, Avital Mulai, Sali Usher, Ariella Zivelin, Avihai Segal, Zahavi Weisman, Moshe Mittelman, et al. "The Two Common Mutations Causing Factor XI Deficiency in Jews Stem From Distinct Founders: One of Ancient Middle Eastern Origin and Another of More Recent European Origin." Blood 90, no. 7 (October 1, 1997): 2654–59. http://dx.doi.org/10.1182/blood.v90.7.2654.

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Abstract Previous studies showed that factor XI (FXI) deficiency commonly observed in Ashkenazi Jews is caused by two similarly frequent mutations, type II (Glu117stop) and type III (Phe283Leu) with allele frequencies of 0.0217 and 0.0254, respectively. In Iraqi Jews, who represent the ancient gene pool of Jews, only the type II mutation was observed with an allele frequency of 0.0167. In this study we sought founder effects for each mutation by examination of four FXI gene polymorphisms enabling haplotype analysis in affected Jewish patients of Ashkenazi, Iraqi, and other origins and in Arab patients. Initial population surveys of 387 Middle Eastern Jews (excluding Iraqi Jews), 560 North African/Sephardic Jews, and 382 Arabs revealed allele frequencies for the type II mutation of 0.0026, 0.0027, and 0.0065, respectively. In contrast, the type III mutation was not detected in any of these populations. All 60 independent chromosomes bearing the type III mutation were solely observed in Ashkenazi Jewish patients and were characterized by a relatively rare haplotype. All 103 independent chromosomes bearing the type II mutation in patients of Ashkenazi, Iraqi, Yemenite, Syrian, and Moroccan Jewish origin and of Arab origin were characterized by another distinct haplotype that was rare among normal Ashkenazi Jewish, Iraqi Jewish, and Arab chromosomes. These findings constitute the first example of a mutation common to Ashkenazi Jews, non-Ashkenazi Jews, and Arabs and are consistent with the origin of type II mutation in a founder before the divergence of the major segments of Jews. Our findings also indicate that the type III mutation arose more recently in an Ashkenazi Jewish individual.
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Shpilberg, O., H. Peretz, A. Zivelin, R. Yatuv, A. Chetrit, T. Kulka, C. Stern, E. Weiss, and U. Seligsohn. "One of the two common mutations causing factor XI deficiency in Ashkenazi Jews (type II) is also prevalent in Iraqi Jews, who represent the ancient gene pool of Jews [see comments]." Blood 85, no. 2 (January 15, 1995): 429–32. http://dx.doi.org/10.1182/blood.v85.2.429.429.

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Abstract In recent years four mutations causing factor XI deficiency have been identified in Jews of Ashkenazi (European) origin. Two of them, type II (a nonsense mutation) and type III (a missense mutation), were found to prevail among 125 unrelated Ashkenazi Jews with severe factor XI deficiency. A finding of type II mutation in four unrelated Iraqi- Jewish families raised the possibility that this mutation is also common in Iraqi Jews, who represent the ancient gene pool of the Jews. A molecular-based analysis performed in 1,040 consecutively hospitalized patients disclosed the following results: Among 531 Ashkenazi-Jewish patients, the type II allele frequency was 0.0217 and among 509 Iraqi-Jewish patients, 0.0167 (P = .50). The type III allele frequency in the Ashkenazi-Jewish patients was 0.0254, whereas none of 502 Iraqi-Jewish patients examined had this mutation. These data suggest that the type II mutation was present in Jews already 2.5 millenia ago. The data also indicate that the estimated risk for severe factor XI deficiency in Ashkenazi Jews (due to either genotype) is 0.22% and in Iraqi Jews, 0.03%, and that the estimated risk of heterozygosity in Ashkenazi Jews is 9.0% and in Iraqi Jews, 3.3%. As patients with severe factor XI deficiency are prone to bleeding after injury and patients with partial deficiency may have similar bleeding complications when an additional hemostatic derangement is present, the observed high frequencies should be borne in mind when surgery is planned for individuals belonging to these populations.
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Shpilberg, O., H. Peretz, A. Zivelin, R. Yatuv, A. Chetrit, T. Kulka, C. Stern, E. Weiss, and U. Seligsohn. "One of the two common mutations causing factor XI deficiency in Ashkenazi Jews (type II) is also prevalent in Iraqi Jews, who represent the ancient gene pool of Jews [see comments]." Blood 85, no. 2 (January 15, 1995): 429–32. http://dx.doi.org/10.1182/blood.v85.2.429.bloodjournal852429.

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In recent years four mutations causing factor XI deficiency have been identified in Jews of Ashkenazi (European) origin. Two of them, type II (a nonsense mutation) and type III (a missense mutation), were found to prevail among 125 unrelated Ashkenazi Jews with severe factor XI deficiency. A finding of type II mutation in four unrelated Iraqi- Jewish families raised the possibility that this mutation is also common in Iraqi Jews, who represent the ancient gene pool of the Jews. A molecular-based analysis performed in 1,040 consecutively hospitalized patients disclosed the following results: Among 531 Ashkenazi-Jewish patients, the type II allele frequency was 0.0217 and among 509 Iraqi-Jewish patients, 0.0167 (P = .50). The type III allele frequency in the Ashkenazi-Jewish patients was 0.0254, whereas none of 502 Iraqi-Jewish patients examined had this mutation. These data suggest that the type II mutation was present in Jews already 2.5 millenia ago. The data also indicate that the estimated risk for severe factor XI deficiency in Ashkenazi Jews (due to either genotype) is 0.22% and in Iraqi Jews, 0.03%, and that the estimated risk of heterozygosity in Ashkenazi Jews is 9.0% and in Iraqi Jews, 3.3%. As patients with severe factor XI deficiency are prone to bleeding after injury and patients with partial deficiency may have similar bleeding complications when an additional hemostatic derangement is present, the observed high frequencies should be borne in mind when surgery is planned for individuals belonging to these populations.
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Yunis, JJ, D. Corzo, M. Salazar, JA Lieberman, A. Howard, and EJ Yunis. "HLA associations in clozapine-induced agranulocytosis." Blood 86, no. 3 (August 1, 1995): 1177–83. http://dx.doi.org/10.1182/blood.v86.3.1177.1177.

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Abstract We previously reported preliminary results of association of clozapine- induced agranulocytosis (CA) with HLA-B38, DR4, DQ3 in five Ashkenazi Jewish patients and with HLA-DR2, DQ1 in four non-Jewish patients. In the present study, 31 additional patients with CA, 10 Ashkenazi Jewish, and 21 of non-Jewish ancestry, were studied. HLA alleles and haplotypes were compared among 52 patients (33 Ashkenazi Jewish, 19 non-Jewish) matched for ethnic background and clinical status. Our results show two associations and define the HLA allele markers for the Ashkenazi Jewish and non-Jewish haplotypes associated with CA. The most important markers for susceptibility for CA in Ashkenazi Jewish patients were DRB1*0402, DQB1*0302, and DQA1*0301, and in non-Jewish patients, HLA- DR*02, DQB1*0502, and DQA1*0102. HLA-DRB1*011 and DQB1*0301 were underrepresented in Ashkenazi Jewish patients when compared with controls. We hypothesize that genes of the major histocompatability complex, other than class I and class II, are responsible for CA; among them are the variants of the heat-shock proteins 70 or the tumor necrosis factor loci.
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Yunis, JJ, D. Corzo, M. Salazar, JA Lieberman, A. Howard, and EJ Yunis. "HLA associations in clozapine-induced agranulocytosis." Blood 86, no. 3 (August 1, 1995): 1177–83. http://dx.doi.org/10.1182/blood.v86.3.1177.bloodjournal8631177.

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We previously reported preliminary results of association of clozapine- induced agranulocytosis (CA) with HLA-B38, DR4, DQ3 in five Ashkenazi Jewish patients and with HLA-DR2, DQ1 in four non-Jewish patients. In the present study, 31 additional patients with CA, 10 Ashkenazi Jewish, and 21 of non-Jewish ancestry, were studied. HLA alleles and haplotypes were compared among 52 patients (33 Ashkenazi Jewish, 19 non-Jewish) matched for ethnic background and clinical status. Our results show two associations and define the HLA allele markers for the Ashkenazi Jewish and non-Jewish haplotypes associated with CA. The most important markers for susceptibility for CA in Ashkenazi Jewish patients were DRB1*0402, DQB1*0302, and DQA1*0301, and in non-Jewish patients, HLA- DR*02, DQB1*0502, and DQA1*0102. HLA-DRB1*011 and DQB1*0301 were underrepresented in Ashkenazi Jewish patients when compared with controls. We hypothesize that genes of the major histocompatability complex, other than class I and class II, are responsible for CA; among them are the variants of the heat-shock proteins 70 or the tumor necrosis factor loci.
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Zhou, Yitian, and Volker M. Lauschke. "Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews." Journal of Medical Genetics 55, no. 9 (July 3, 2018): 617–27. http://dx.doi.org/10.1136/jmedgenet-2018-105429.

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BackgroundAdverse drug reactions are a major concern in drug development and clinical therapy. Genetic polymorphisms in genes involved in drug metabolism and transport are major determinants of treatment efficacy and adverse reactions, and constitute important biomarkers for drug dosing, efficacy and safety. Importantly, human populations and subgroups differ substantially in their pharmacogenetic variability profiles, with important consequences for personalised medicine strategies and precision public health approaches. Despite their long migration history, Ashkenazi Jews constitute a rather isolated population with a unique genetic signature that is distinctly different from other populations.ObjectiveTo provide a comprehensive overview of the pharmacogenetic profile in Ashkenazim.MethodsWe analysed next-generation sequencing data from 5076 Ashkenazim individuals and used sequence data from 117 425 non-Jewish individuals as reference.ResultsWe derived frequencies of 164 alleles in 17 clinically relevant pharmacogenes and derived profiles of putative functional consequences, providing the most comprehensive data set of Jewish pharmacogenetic diversity published to date. Furthermore, we detected 127 variants with an aggregated frequency of 20.7% that were specifically found in Ashkenazim, of which 55 variants were putatively deleterious (aggregated frequency of 9.4%).ConclusionThe revealed pattern of pharmacogenetic variability in Ashkenazi Jews is distinctly different from other populations and is expected to translate into unique functional consequences, especially for the metabolism of CYP2A6, CYP2C9, NAT2 and VKORC1 substrates. We anticipate that the presented data will serve as a powerful resource for the guidance of pharmacogenetic treatment decisions and the optimisation of population-specific genotyping strategies in the Ashkenazi diaspora.
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Fridjesi, Judit. "The ′ugliness′ of Jewish prayer: Voice quality as the expression of identity." Muzikologija, no. 7 (2007): 99–118. http://dx.doi.org/10.2298/muz0707099f.

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This article is based on the musical material and interviews the author collected in Hungary, France, Czechoslovakia, the USA and Israel in the course of thirty years of her fieldwork among the traditional East-Ashkenazi Jews. It relates to the aesthetic concepts of the prayer chant of the Ashkenazi Jews of East Europe (?East -Ashkenazim?) as it appears to have existed before World War II, survived in the oral tradition until the 1970s and exists sporadically up to the present.
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Buchbinder, Jacob T., Yoram Bilu, and Eliezer Witztum. "Ethnic Background and Antecedents of Religious Conversion among Israeli Jewish Outpatients." Psychological Reports 81, no. 3_suppl (December 1997): 1187–202. http://dx.doi.org/10.2466/pr0.1997.81.3f.1187.

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This study explored the association of ethnocultural background (Ashkenazi vs Sephardi origin) with antecedents of religious conversion among Israeli Jewish penitents who applied for psychiatric help in an outpatient clinic. A basic assumption underlying the comparison was that Sephardic Jews in Israel are more inclined toward Jewish tradition and collectivistic than Ashkenazim. The interview data indicated that for both groups emotional factors were more dominant in the conversion process than cognitive ones; however, cognitive factors were more strongly present in the conversion process of the Ashkenazim whose prepenitence cultural orientation had been more secularized and individualistic. In both groups a high prevalence of problematic relations with the father (but not with the mother) during childhood was noticed. Over-all, conversion tended to be gradual rather than abrupt and devoid of mystical experiences.
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Charrow, Joel. "Ashkenazi Jewish genetic disorders." Familial Cancer 3, no. 3-4 (2004): 201–6. http://dx.doi.org/10.1007/s10689-004-9545-z.

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Dissertations / Theses on the topic "Ashkenazi Jewish"

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Antebi, Yael Jennifer. "Genetic predisposition to ovarian cancer in Ashkenazi Jewish families." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0009/MQ40766.pdf.

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Mozersky, J. "'Ashkenazi mutations' and the BRCA genes : genetics, disease and Jewish identity." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/19035/.

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This thesis explores the increased risk of genetic breast cancer for Ashkenazi Jews who are at significantly increased risk of carrying three specific mutations in the high risk breast cancer genes, BRCA1 and BRCA2. The Ashkenazi Jewish population has the highest known risk of genetic breast cancer and are the most well researched in relation to genetic disease. They are believed to have a particularly supportive and unique relationship with genetics, despite also having a history of discrimination that includes claims of biological inferiority. The use of racial or ethnic groups in genetic research is highly contentious and the implications for those populations being studied are usually assumed to be negative. There is also significant discussion about the potential of new genetic knowledge to transform individual and collective identity and alter how individuals conceive of themselves and the groups to which they belong. This thesis contributes to both of these areas of debate by exploring the implications for individuals of knowing that they are at increased risk of genetic breast cancer because they are of Ashkenazi Jewish origin. It specifically addresses whether being at increased risk has an impact on how Ashkenazi Jewish women feel about their own Jewish identity, whether they have concerns about current genetic research related to them, and if they are particularly supportive as if often claimed. Evidence is provided principally from qualitative interview material with Ashkenazi women at increased risk of genetic breast cancer as well as non high risk individuals. The qualitative data is supplemented by a quantitative survey. Ethnic identity can be an important mediating factor for the ways in which genetic knowledge is interpreted and genetic medicine can become intertwined with culturally specific issues. Ashkenazi Jews conceive of themselves, their history and their future in ways that are compatible with new genetic knowledge. While it is important not to assume there are necessarily damaging or transformative consequences for those populations that are the subjects of genetic research, there were implications for Ashkenazi women and their disease was interwoven with their identity in complex ways.
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Levine, A. P. "The genetics of inflammatory bowel disease in extended multiplex Ashkenazi Jewish kindreds." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1461013/.

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The inflammatory bowel diseases (IBD), Crohn’s disease and ulcerative colitis, are chronic inflammatory diseases predominantly affecting the gastrointestinal tract. They are of unknown aetiology; however, there is a significant genetic component. A multitude of studies have identified common genetic variants associated with these diseases; however, they only account for a proportion of the disease heritability. The study of large families with many affected individuals is theoretically a powerful method for identifying rare disease causing variants that might contribute to this ‘missing heritability’. To date, this approach has not been successfully employed in IBD owing, in part, to the moderate size of families identified. This thesis describes the ascertainment, phenotypic and genomic characterisation of two extended multi-plex Ashkenazi Jewish (AJ) kindreds with over 50 and 25 cases of IBD, respectively. An interrogation of the possible mechanisms underlying this familial aggregation highlighted a partial role for common disease associated variants. Linkage analysis was employed in an attempt to identify loci segregating with the disease. A novel method for reconstructing haplotype flow information across extended pedigrees is described and implemented in these kindreds demonstrating the absence of a single locus shared by all affected individuals. Exome sequencing a cohort of unrelated AJ individuals and cases from the families permitted the prioritisation of a number of candidate variants however, these did not reach an empirical significance thresh-old as defined using a Monte Carlo gene-dropping approach. It is possible that the analyses of these data in combination with those from additional families may yield significance. However it is clear that even in extended families with many affected individuals, the genetics of IBD remains complex.
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Besterman-Dahan, Karen. "Cultural Factors and Concepts of Pollution: Colorectal Cancer and Health Behaviors among Ashkenazi Jewish Women." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002720.

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Hirschberg, Jack Jacob. "Secular and Parochial education of Ashkenazi and Sephardi Jewish children in Montreal : a study in ethnicity." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75920.

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The objective of this study was to determine whether formal, primary education could increase the level of ethnicity in children. One hundred Jewish children completing grade 6, and their parents, were measured on a series of instruments designed to evaluate their level of ethnic identity. Half the children had received their full education in private, parochial schools, while the other half had attended public, secular schools. The two samples were further sub-divided so that each sample consisted of 25 children of Ashkenazi descent and 25 of Sephardi descent. The data were subjected to a multivariate analysis of covariance wherein the variance attributable to the parents was partialled out. The results indicated that formal, parochial education does not effect an increase in the level of ethnicity, and that parental and community factors are the primary determinants of a child's ethnic identity. The results also demonstrate that the Sephardi children, despite their affinity to the Jewish people, have a less positive image of the Jewish community when compared to the Ashkenazi majority. The Conflict Theory model, which views the school as a mirror of the forces in society at large, was seen as the best explanation of the data.
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Lew, Raelia Monique. "Tay Sachs Disease: Analysis Of Australian Screening Strategies (1995-2013)." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15703.

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Introduction: Tay Sachs Disease (TSD) is a fatal genetic disorder with autosomal recessive inheritance, occurring more frequently in Ashkenazi Jewish (AJ) populations. No cure or effective treatment exists. Carrier couples have a 1 in 4 risk that a baby will have TSD. The desire to prevent TSD inspired the first pre-conception genetic screening programs. The development of assisted reproductive technologies and pre-implantation genetic diagnosis of embryos has broadened reproductive options available for carrier-couples to avoid having a child with a serious genetic condition. Aim: My aims were to discover: • The allelic distribution of HEXA mutations in the Australian AJ community • The accuracy of TSD carrier risk self-determination in AJ individuals aged 20 to 40 years when questioned by health professionals • Evidence that TSD carrier screening prevents cases • Evidence of reported access to TSD screening • Evidence to make recommendations for primary care clinicians about TSD screening. • Clinical impacts and ethical issues raised by expanded genetic screening strategies. Methods: This thesis by publication represents my research work with Australian TSD screening programs (2008-2013). Results: A high TSD carrier frequency exists amongst Australian AJ individuals currently aged 20-40 years. Disclosure of AJ heritage can accurately predict TSD carrier risk. Screening programs have been effective in preventing TSD cases. Systematic review of the international literature on TSD screening formed NHMRC graded evidence-based best practice recommendations for primary care clinicians. Australasian clinical practice guidelines for genetic screening in Ashkenazi Jews are presented. Conclusion: Preconception genetic screening is effective in rare recessive disease prevention, with important implications for Australian health-economic policy.
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MacDonald-Dennis, Christopher. "Competing narratives : the interplay between racial and ethno-religious identity among Ashkenazi Jewish undergraduate anti-racist peer educators /." Ann Arbor, MI : University Microfilms, 2005. http://proquest.umi.com/dissertations/preview/3193920.

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Benditson, Mindi Ellen. "Inside/Outside/In-between: Understanding how Jewish Identity Impacts the Lives and Narratives of Ashkenazi Female Public School Educators." Chapman University Digital Commons, 2016. http://digitalcommons.chapman.edu/ces_dissertations/11.

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Since Ashkenazi Jews in the United States are not a visible minority, it often becomes difficult to distinguish what/who is a Jew. As many Jewish females may appear to be of the dominant culture, they often get overlooked in discussions and courses on teacher education and multiculturalism/multicultural education. However, their identity as both Jewish and White and the absence of conversation regarding their multiple positions in education and in society can contest, as well as support, their connection to multiculturalism. The purpose of this research was to identify how four middle class Ashkenazi females in the greater Los Angeles area understand their identities and experiences as Jews and as public school educators, how these multiple identities impact their perceptions of their pedagogy, and how these women navigate the structures of public schooling. Narrative Inquiry and Listening Guide method of analysis were utilized to present multilayered portraits of these women in order to challenge the status quo of the White female teacher identity and the positioning of Jewish females in regards to the perseverance of Christianity in public education. Story threads emerged from the narratives which indicated that while Jewish identity is fluid and exists on a continuum over time, it was not a primary reason why these women became teachers. Although each woman made individual decisions regarding the degree to which her Jewishness was presented in the classroom and on campus, they did not actively design their curriculum due to them being Jewish; rather they unconsciously incorporated aspects of Judaism in their pedagogy.
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Kellerman, Aliza C. "Kvetching with Comics: How 20th Century American Comics Reflect the Ashkenazi Ethos of Pride and Shame." Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/cmc_theses/750.

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One of the most fundamental ways of understanding the struggles and delights of an ethnic group is to study the art the group produces. Art –visual, literary, auditory– functions as an expression of the history of the group. Often, what is considered great art in one culture is disparaged in many others. In my thesis, I will be examining how comics function as an expression of simultaneous pride and shame among Ashkenazi Jews, particularly comics created in the 20th century. Perhaps comics do not seem like an obvious expression of Eastern European Judaism. After all, there are far more renowned, and even sophisticated works to look at, such as the whimsical art of Marc Chagall and stately rabbinical paintings of Isidor Kauffman, or even the heady philosophical work of Theodor W. Adorno. “Ashkenazi expression” and “comics” do not seem intuitively connected. This disconnect is precisely why I want to explore the relationship between comics and Ashkenazi Jewry. In addition to many of the most prominent comic creators being Jewish, I posit that there is something inherently yiddish, Jewish, about American comics. The purpose of this essay is not to name individual comic artists in an attempt to prove the Jewishness of the the comic-book industry. Rather, I will explore why Jews of Eastern European descent gravitated toward the comic-book industry in the early to mid 20th century. I posit that American comics acted as an expression of a pride-shame tension found in American Jews of Eastern European descent. To explore this connection, I will first examine the origins of simultaneous Jewish pride and shame by tracing the roots of Eastern European Jewish self-hatred. Next, I will delve into why comics encapsulate this balance of self-deprecation and self-glorification. I will analyze both the nature of the medium itself, and the circumstances grounding the formation of American comics. Ashkenazi Jews, or Jews of Eastern European, specifically German descent, have been at the center of much scholarly literature. Although an extremely small percentage of the world's population, the bulk of Jews are Ashkenazi, as opposed to Sefardic. Much literature has been devoted to Ashkenazi Judaism, as the ethnic division has produced an impressive body of scientific and literary accomplishment. Although the countries from which Ashkenazi Jews originate are diverse, the key words surrounding Ashkenazi discourse are reoccurring. Concepts such as “exile,” “self-hatred,” and “Jewish humor” all arise. Another central concept is Yiddishkeit. Yiddishkeit literally translates to “Jewishness” in none other but the language of Yiddish. Yiddish has been the subject of both outward Ashkenazi expression –there is a great deal of Yiddish literature and art– and scholarly examination. Perhaps most recently, Michael Wex published a book called Born to Kvetch, an in-detail study of the history of Yiddish, and how it embodies Ashkenazi culture. Within this book, a particular theme appears: the theme of simultaneously occuring pride and shame. Jews created Yiddish as a result of the primary culture's rejection. However, after this initial dismissal, great pride emerged out of Yiddish, manifesting itself in rich Yiddish culture. Other scholars have explored the concept of Jewish self-hatred, and the fine line this self-hatred straddles between bona fide self-hatred and isolationist pride. Sander Gilman, who writes extensively about the topic, discusses how language and literature embody this dichotomous tension of pride and shame. While conducting research for the connection between comics and class in 20th century American, I came to the understanding that many of the founders of and participants in the American comic industry were Jewish. I dug up analyses of specific comics/graphic novels (usually Maus) exploring certain Jewish themes in comics, yet I had a hard time finding extensive research asking the question as to why comics and Jews have such a strong connection. In my thesis, I hope to further this question by not only investigating the circumstances surrounding comics that made Jews turn to the industry, but why comics themselves embody Jewish pride and shame. On a much humbler scale, I hope to accomplish what Wex has in Born to Kvetch, a linguistic analysis that provides insight into the greater ethnic group engaging with it. In chapter one, I will establish the pride-shame dichotomy found in Ashkenazi Judaism. I will first explore several biblical passages, including Lamentations, Micah, and Isaiah. By exploring these instances in the tanach, I will try to establish the uniqueness the Jews feel due to their personal and punitive relationship with God. Throughout these passages, we will see the Jews taking pride in the punishment God doles out for them, because such pain is indicative of the Jews' superiority among other nations. Next, I will provide a brief explanation of why I am choosing to focus on the act of conversion in the Medieval time period as an indicator of Jewish pride and shame. In specific, I will focus on infamous Johannes Pfefferkorn, who converted from Judaism to Christianity. Pfefferkorn is the perfect example of a Jew who both detested his Judaism, yet used it to his advantage to speak authoritatively about Judaism to Christians, as his professed textual knowledge gave him clout. Next, I will give an introduction on the connection between Otherness and language, explaining how Hebrew and the Talmud spurred both fascination and disgust toward Jews from their surrounding neighbors. After segueing into the origins of Yiddish as a language created out of exile, I will explain how though Yiddish originated out of spurning, the language became a source of pride of its rejected roots. I will consider the statements of various Yiddish authors, in particular American immigrant Isaac Bashevis Singer. Through both an analysis of Singer's self-reflection of his own life and an analysis of his short story, Gimpel the Fool, I will establish the pride Ashkenazi Judaism takes in its outsider status. Singer himself remarks of the positivity of being lonely and different. His character, Gimpel, is a foolish outcast. Much like the Jews in the biblical passages explored earlier in the chapter, he suffers constant misfortune and mockery, yet his very pain is what lends him favor in God's eyes. In chapter two, I will explore how 20th century American comics reflect the Ashkenazi dichotomy of pride and shame. Much like Yiddish is not a mainstream language, the idea of comics as mainstream art or literature has been greatly contested. I will try to determine which circumstances surrounding 20th century comics, and the comics themselves, connect with this pride-shame tension. I will use Paul Buhle's Jews and American Comics as a frame of reference, since the book often links comics and Yiddish. I will first give a brief history of the American comic-book, starting with the Hogan's Alley comics strip, and exploring up until the mid 20th century. By understanding the working-class origins of comics, we can better understand the low-brow perception of them from the standpoint of both their readers and their critics. I will then explain how American comics in the 20th century contained Jewish themes of pride and shame, despite their characters not being explicitly Jewish. I will more closely explore this idea through an analysis of the character Superman, drawing on both the commentary from the character's creators and the content clues of the character himself. A true foreigner, Superman masks his real identity, his superhuman powers. While his alias is what makes him exceptional, it is also the thing he abhors the most. Will Eisner, a giant in the world of comics, denies inserting Jewish identity in his own characters. However, his assistant, Jules Feiffer, half-jokingly claimed that his character, Denny Colt, featured in Eisner's The Spirit series, is in actuality a secret Jew. Instead of focusing on Colt and The Spirit, I will do a close reading of one of Eisner's other works, A Contract with God, which is an exemplary work of Jewish pride and shame. Contract contains a motif that is similar to that of the biblical passages analyzed in chapter one. The protagonist, Russian-American immigrant Frimme Hershe, has a personal relationship with God that leaves him demoralized and punished. I will then explore the use of visual stereotype in Contract, comparing it to that of Art Spiegelman's Maus, and contrasting it with that of the film Inglorious Basterds. I will argue that through engaging with Jewish visual stereotypes, the first two reveal them as falsehoods. Thus, through an admittance of these shamed images, the comics mock them. The latter film chooses to ignore stereotypes, thus leaving them extant. I will conclude the chapter by positing that Jews have coped with their constant exile through through the self-deprecation of comics. Buhle mentions that comics about Jewish-American gangsters turned into a source of pride, presumably for Ashkenazi American Jews. The trope, hated by others, was lauded by those it was forced upon. Much like Yiddish, comics may have been born out of exclusion, but they came to be a source of pride among Ashkenazi Jews.
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Marcus, Alexander Warren. "Auschwitz has happened: an exploration of the past, present, and future of Jewish redemption." Pomona College, 2009. http://ccdl.libraries.claremont.edu/u?/stc,62.

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Ch. 1: Introduction: A Destruction without Adequate Precedent. Ch. 2: Rupture and the Holy Ideal: Redemption in the Hebrew Bible. Ch. 3: Giving the Sense: The Rise of Commentary. Ch. 4: Rabbi Eliezer’s Silence. Ch. 5: Gold and Glass: Ethical Rupture in Mystical Union? Ch. 6: Our Impossible Victory.
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Books on the topic "Ashkenazi Jewish"

1

Joshua, Singer Israel. The brothers Ashkenazi. New York: Other Press, 2010.

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Samuel Jaffe ben Isaac Ashkenazi. Sifre Rabi Shemuʼel Yafeh Ashkenazi. Yerushalayim: Ḥ. Ṿagshal, 1988.

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Aviner, Shelomoh Ḥayim. Perurim mi-shulḥan gavoha: Mi-torato shel ha-Rav Yehuda Leʾon Ashkenazi. Yerushalayim: S. Aviner, 2001.

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Maʻaśeh roḳem: Tashmishe ḳedushah me-ṭeḳstil be-vet ha-keneset ha-Ashkenazi, ha-Sefaradi, ṿeha-Iṭalḳi. Yerushalayim: Mekhon Ben-Tsevi le-ḥeḳer ḳehilot Yiśraʼel ba-Mizraḥ, 2009.

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Luria, Isaac ben Solomon, and Yosef Ḥayim ben ʻOvadyah Mizraḥi. Seder Tiḳun ḥamishah be-Av: Le-yom peṭirat ha-meḳubal ha-Elohi ... Yitsḥaḳ Lurya Ashkenazi. Yerushto [i.e., Jerusalem]: Y. ben D. Salem, 2009.

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Ashkenazi, Mosheh Yaḳar. Zeh ha-ḥibur meʻaṭ ha-kamut ṿe-rav ha-ekhut: Ḥibro ha-r. R. Mosheh Yaḳar Ashkenazi, zatsal, ṿe-ḳarʼo Petaḥ ʻenayim ... . [Brooklyn, N.Y.?: ḥ. mo. l., 1992.

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Emden, Jacob. Sefer Yatsiv pitgam: Devarim meʼirim ḳedoshim u-ṭehorim ... ṿehu derush ṿe-hesped ... ʻal ... Tsevi Hirsh Ashkenazi ... ; ṿe-nilṿeh la-zeh Sefer Megilat sefer. Bruḳlin, N.Y: Aḥim Goldenberg, 1991.

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Emden, Jacob. Sefer Yatsiv pitgam: Devarim meʼirim ḳedoshim u-ṭehorim ... ṿehu derush ṿe-hesped ... ʻal ... Tsevi Hirsh Ashkenazi ... ; ṿe-nilṿeh la-zeh Sefer Megilat sefer. Bruḳlin, N.Y: Aḥim Goldenberg, 1991.

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From lowly metaphor to divine flesh: Sarah the Ashkenazi, Sabbatai Tsevi's messianic queen and the Sabbatian movement. Amsterdam: Menasseh ben Israel Instituut, 2012.

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Joel ben Simeon, 15th cent., Eleazar ben Judah, of Worms, 1176 (ca.)-1238., Goldstein David 1933-, and British Library, eds. The Ashkenazi Haggadah: A Hebrew manuscript of the mid-15th century from the collections of the British Library. New York: H.N. Abrams, 1985.

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Book chapters on the topic "Ashkenazi Jewish"

1

Levy, Yamin. "A Study of Two Traditions Sephardi and Ashkenazi." In Routledge Handbook of Jewish Ritual and Practice, 163–78. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003032823-14.

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Spector-Bitan, Graciela. "Portrayals of the internal God among Ashkenazi Jewish Orthodox lesbians in Israel." In Jewish Lesbian Scholarship in a Time of Change, 35–50. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003140368-3.

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Salmon, Laura. "Melancholic Humor, Skepticism and Reflective Nostalgia. Igor’ Guberman’s Poetics of Paradox." In Biblioteca di Studi Slavistici, 107–47. Florence: Firenze University Press, 2015. http://dx.doi.org/10.36253/978-88-6655-822-4.06.

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The poetry of Israeli émigré Igor' Guberman, comprising thousands of quatrains (‘gariki’), represents a hybrid genre at the junction of Jewish aphoristic tradition, Russian oral folklore, and classical Russian poetry. The theme of toska, which is central to the gariki, may be sharply distinguished from the ‘restorative nostalgia’ theorized by Svetlana Boym (2001): Guberman's toska is a thoughtful, melancholic, and paradoxical feeling. It expresses a particular variety of skepticism that characterizes the paradoxical humor of the Ashkenazi, the purpose of which is not to ridicule others' shortcomings, but to gently make fun of the sadness and painful absurdity that impermeates human existence. Such melancholic and paradoxical humor permits Guberman to look at life, at himself, even at God, with an indulgent ‘smile of reason’ that is absolutely devoid of arrogance. A subtle melancholic and deep skeptic, Guberman "laughs through his tears", for this is what Russian-Jewish tradition teaches, a lesson that has penetrated deeply and more generally into Russian literature: when the soul is beset by excessive sadness, its has recourse only to laughter.
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"Ashkenazi Jewish Cuisine." In Jewish Cuisine in Hungary, 37–47. Central European University Press, 2019. http://dx.doi.org/10.7829/j.ctv179h1tk.6.

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"3. Jewish (Ashkenazi Influences)." In A Handbook of Biblical Reception in Jewish, European Christian, and Islamic Folklores, 87–110. De Gruyter, 2017. http://dx.doi.org/10.1515/9783110286724-008.

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Ta-Shma, Israel M. "On the History of the Jews in Twelfth- and Thirteenth-Century Poland." In Polin: Studies in Polish Jewry Volume 10, translated by David Louvish, 287–318. Liverpool University Press, 1997. http://dx.doi.org/10.3828/liverpool/9781874774310.003.0012.

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This chapter traces the history of the Jews in twelfth- and thirteenth-century Poland. Jewish traders of Ashkenazi origin passed through Poland on their way to Russia on business as early as the first half of the eleventh century. The Jewish traders who passed through Poland in the twelfth century included scholars and other individuals versed in religious learning. By the last quarter of the twelfth century, there was a well-established Jewish community in Cracow, probably a direct descendant of the community whose existence was recorded some 150 years earlier. The chapter then considers a variety of Hebrew sources that reveal more about the existence of an admittedly sparse Jewish presence, including Jews well versed in Torah, in thirteenth-century Poland; about the continuous existence of this presence throughout the twelfth and thirteenth centuries; and, above all, about its Ashkenazi origins and its special, ongoing contacts with the circles of ḥasidei Ashkenaz in Germany. The extent of the links between Russia–Poland and Ashkenaz, particularly eastern Ashkenaz, was much greater than believed up to the present. Moreover, these links were essentially persistent and permanent, rather than a series of random occurrences.
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"Genetic admixture of Ashkenazi Jews." In The Jewish Journey. I.B.Tauris, 2016. http://dx.doi.org/10.5040/9780755692590.ch-024.

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Westreich, Elimelech. "The Ban on Polygamy in Polish Rabbinic Thought." In Polin: Studies in Polish Jewry Volume 10, 66–84. Liverpool University Press, 1997. http://dx.doi.org/10.3828/liverpool/9781874774310.003.0003.

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This chapter investigates Polish rabbinical treatments of the medieval Ashkenazi ban on polygamy. The Ban of Rabbenu Gershom forbade both polygamy and divorcing a woman against her will. Its promulgation brought about a revolutionary change in Ashkenazi Jewish family life and in the body of law that regulated it. This Ban has been seen by historians as a key determinant of the singularity of Ashkenazi Jewish culture. Hence, analysis of its fate in Poland is a most appropriate means of examining how far Polish rabbis adhered to the Ashkenazi legal tradition. In sixteenth-century Poland, there were two approaches among halakhic scholars. One adheres strictly to the Ashkenazi tradition, while the other is more open to the influence of other Jewish cultural spheres.
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"Modernism of the Ashkenazi Jewish Diaspora." In Global Modernists on Modernism. Bloomsbury Academic, 2019. http://dx.doi.org/10.5040/9781474242356.pt-015.

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"Hakham Zevi Ashkenazi, Responsum No. 18." In Spinoza’s Challenge to Jewish Thought, 12–18. Brandeis University Press, 2019. http://dx.doi.org/10.2307/j.ctv102bhtj.7.

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Conference papers on the topic "Ashkenazi Jewish"

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Stenzel, Stephanie L., Jeremy Gollub, Michael Shapero, Andrea Finn, Gad Rennert, and Stephen B. Gruber. "Abstract 2560: MicroRNA target site polymorphisms and colorectal cancer risk in the Ashkenazi Jewish population." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2560.

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Schwenter, Frank, Leon Raskin, Marina Freytsis, Faina Bogomolniy, Melyssa Aronson, Gad Rennert, Steven Gallinger, et al. "Abstract 2975: Two putative founder MSH6 mutations associated with inherited cancer susceptibility in Ashkenazi Jewish population." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2975.

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Rozenblum, Ester, Jose Sotelo, Gina Y. Kim, Susana Korolevich, Hongling Liao, James Cherry, David J. Munroe, and Anna Roschke. "Abstract 3265: Immortalization and comprehensive characterization of a human ovarian adenocarcinoma cell line derived from an Ashkenazi Jewish patient." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3265.

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Vijai, Joseph, Sabine Topka, Kara Maxwell, Vignesh Ravichandran, Tinu Thomas, Danylo Villano, Ann Maria, et al. "Abstract 796: ERCC3 R109X is a moderate risk breast cancer risk variant in Ashkenazi Jews." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-796.

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Manchanda, R., M. Burnell, F. Gaba, R. Desai, J. Wardle, S. Gessler, L. Side, et al. "Randomised trial of unselected BRCA testing in ashkenazi jews: long term outcomes and factors affecting uptake of testing." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.15.

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Manchanda, R., M. Burnell, F. Gaba, S. Sanderson, K. Loggenberg, S. Gessler, J. Wardle, et al. "81 Attitude towards and factors affecting uptake of population based BRCA testing in ashkenazi jews: a cohort study." In IGCS Annual 2019 Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-igcs.81.

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Burnell, Matthew, Faiza Gaba, Michail Sideris, Monika Sobocan, Rakshit Rakshit, Saskia Sanderson, Kelly Loggenberg, et al. "2022-RA-1465-ESGO Randomised trial of population based BRCA testing in Ashkenazi Jews: long term secondary lifestyle behavioural outcomes." In ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.861.

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Reports on the topic "Ashkenazi Jewish"

1

Hurley, Karen, and William Redd. Decision-Making Regarding Prophylactic Mastectomy and Oophorectomy in Ashkenazi Jewish Women Seeking Genetic Testing for BRCA1/BRCA2 Mutations. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada396788.

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Friedrichsen, Danielle. Positional Cloning of an Ashkenzai Jewish Hereditary Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada454005.

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Ostrer, Harry. Genetic Susceptibility to Prostate Cancer Among Ashkenazi Jews. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada421961.

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Ostrer, Marry, and Carole Oddoux. Genetic Susceptibility to Prostate Cancer Among Ashkenazi Jews. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada392290.

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