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Journal articles on the topic 'Associate between models'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Sandeep, Kaur*. "COMPARATIVE ANALYSIS OF SOFTWARE DEVELOPMENT MODELS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 10 (2017): 611–17. https://doi.org/10.5281/zenodo.1036644.

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No geek is unfamiliar with the concept of software development life cycle (SDLC). This research deals with the various SDLC models covering waterfall, spiral, and iterative, agile, V-shaped, prototype model. In the modern era, all the software systems are fallible as they can’t stand with certainty. So, it is tried to compare all aspects of the various models, their pros and cons so that it could be easy to choose a particular model at the time of need

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Kessler, Marciane, Suzinara Beatriz Soares de Lima, Teresinha Heck Weiller, Luís Felipe Dias Lopes, Lucimare Ferraz, and Elaine Thumé. "Longitudinality in Primary Health Care: a comparison between care models." Revista Brasileira de Enfermagem 71, no. 3 (2018): 1063–71. http://dx.doi.org/10.1590/0034-7167-2017-0014.

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ABSTRACT Objective: to evaluate the attribute longitudinality in different models of assistance in Primary Health Care and observe its association with demographic, socioeconomic and health care characteristics. Method: a cross-sectional study, carried out in 2015 with 1076 adult users of primary care services in the 32 cities of the 4th Regional Health Care Core of Rio Grande do Sul State. The Primary Care Assessment Tool was used with definition of low (<6.6) or high (≥6.6) score for longitudinality. The association with independent variables was observed through the Poisson regression. R

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McFrederick, Quinn S., Jamie J. Cannone, Robin R. Gutell, Katrin Kellner, Robert M. Plowes, and Ulrich G. Mueller. "Specificity between Lactobacilli and Hymenopteran Hosts Is the Exception Rather than the Rule." Applied and Environmental Microbiology 79, no. 6 (2013): 1803–12. http://dx.doi.org/10.1128/aem.03681-12.

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ABSTRACTLactobacilli (Lactobacillales:Lactobacillaceae) are well known for their roles in food fermentation, as probiotics, and in human health, but they can also be dominant members of the microbiota of some species of Hymenoptera (ants, bees, and wasps). Honey bees and bumble bees associate with host-specific lactobacilli, and some evidence suggests that these lactobacilli are important for bee health. Social transmission helps maintain associations between these bees and their respective microbiota. To determine whether lactobacilli associated with social hymenopteran hosts are generally ho

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Christenson, Holly M., George D. Becker, Anson D’Aloisio та ін. "The Relationship between IGM Lyα Opacity and Galaxy Density near the End of Reionization". Astrophysical Journal 955, № 2 (2023): 138. http://dx.doi.org/10.3847/1538-4357/acf450.

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Abstract Observed scatter in the Lyα opacity of quasar sightlines at z < 6 has motivated measurements of the correlation between Lyα opacity and galaxy density, as models that predict this scatter make strong and sometimes opposite predictions for how they should be related. Our previous work associated two highly opaque Lyα troughs at z ∼ 5.7 with a deficit of Lyα emitting galaxies (LAEs). In this work, we survey two of the most highly transmissive lines of sight at this redshift toward the z = 6.02 quasar SDSS J1306+0356 and the z = 6.17 quasar PSO J359-06. We find that both fields are un

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Dai, Zhiming, Tian Tian, Meng Wang, et al. "CTLA-4 polymorphisms associate with breast cancer susceptibility in Asians: a meta-analysis." PeerJ 5 (January 10, 2017): e2815. http://dx.doi.org/10.7717/peerj.2815.

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Previous studies have investigated the association between cytotoxic T-lymphocyte antigen-4 (CTLA-4) polymorphisms and breast cancer susceptibility, but the results remained inconsistent. Therefore, we evaluated the relationship between four common CTLA-4 polymorphisms and breast cancer risk by a meta-analysis, aiming to derive a comprehensive and precise conclusion. We searched EMBASE, Pubmed, Web of Science, CNKI, and Wanfang databases until July 18th, 2016. Finally, ten eligible studies involving 4,544 breast cancer patients and 4,515 cancer-free controls were included; all these studies we

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Khalidov, Vasil, Florence Forbes, and Radu Horaud. "Conjugate Mixture Models for Clustering Multimodal Data." Neural Computation 23, no. 2 (2011): 517–57. http://dx.doi.org/10.1162/neco_a_00074.

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The problem of multimodal clustering arises whenever the data are gathered with several physically different sensors. Observations from different modalities are not necessarily aligned in the sense there there is no obvious way to associate or compare them in some common space. A solution may consist in considering multiple clustering tasks independently for each modality. The main difficulty with such an approach is to guarantee that the unimodal clusterings are mutually consistent. In this letter, we show that multimodal clustering can be addressed within a novel framework: conjugate mixture

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Sanders, Jason. "Associations Between Aging-Related Biomarkers, Interstitial Lung Abnormalities, and Mortality." Innovation in Aging 4, Supplement_1 (2020): 749. http://dx.doi.org/10.1093/geroni/igaa057.2698.

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Abstract Interstitial lung abnormalities (ILA) exist in ~10% of adults &gt;50 and associate with increased morbidity/mortality. Their pathobiology is poorly understood; age is the strongest risk factor. In the Framingham Heart Study, we determined associations between ILA and 10 blood biomarkers previously robustly associated with aging and mortality. Odds of ILA increased directly with ln-transformed GDF15 (OR [95% CI] = 3.20 [1.74-5.91], p=0.0002), TNF-αRII (2.41 [1.34-4.34], p=0.003), IL6 (1.76 [1.39-2.22], p&lt;0.0001), insulin (1.56 [1.11-2.20], p=0.01), and CRP (1.53 [1.27-1.84],

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XU, HAO, and CHLOÉ ARSON. "ANISOTROPIC DAMAGE MODELS FOR GEOMATERIALS: THEORETICAL AND NUMERICAL CHALLENGES." International Journal of Computational Methods 11, no. 02 (2014): 1342007. http://dx.doi.org/10.1142/s0219876213420073.

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A new anisotropic damage model for rock is formulated and discussed. Flow rules are derived with the energy release rate conjugate to damage, which is thermodynamically consistent. Drucker–Prager yield function is adapted to make the damage threshold depend on damage energy release rate and to distinguish between tension and compression strength. Positivity of dissipation is ensured by using a nonassociate flow rule for damage, while nonelastic deformation due to damage is computed by an associate flow rule. Simulations show that the model meets thermodynamic requirements, follows a rigorous f

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Murrar, Sohad, Laila Azam, Benish Baqai, Omar Davila, and Aasim I. Padela. "Relationships Between Religious Commitment, Workplace Experiences, and Professional and Psychological Outcomes Among U.S. Muslim Physicians." Academic Medicine 99, no. 12 (2024): 1423–31. https://doi.org/10.1097/acm.0000000000005686.

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Abstract Purpose To examine relationships between religiosity, workplace discrimination, religious accommodation, and related professional and psychological outcomes among U.S. Muslim physicians. Method In 2021, the authors surveyed 264 physicians from 3 U.S.-based Muslim clinician organizations. Religious commitment, as measured by multiple items, was evaluated as a possible predictor of workplace discrimination and accommodation; job turnover; career satisfaction; workplace motivation; and belonging, burnout, and depression. Bivariate regression models were used to identify possible signific

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Wood, A. C., E. K. Kabagambe, I. B. Borecki, H. K. Tiwari, J. M. Ordovas, and D. K. Arnett. "Dietary Carbohydrate Modifies the Inverse Association between Saturated Fat Intake and Cholesterol on Very Low-Density Lipoproteins." Lipid Insights 4 (January 2011): LPI.S7659. http://dx.doi.org/10.4137/lpi.s7659.

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We aimed to investigate the relationship between dietary saturated fat on fasting triglyceride (TG) and cholesterol levels, and any mediation of this relationship by dietary carbohydrate intake. Men and women in the NHLBI Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN) study ( n = 1036, mean age ± SD = 49 ± 16 y) were included. Mixed linear models were run with saturated fat as a predictor variable and fasting TG, very low density lipoprotein cholesterol (VLDL-C), low density cholesterol (LDL-C) and high density cholesterol (HDL-C) as separate outcome variables. Subsequent models wer

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ADLER, MARK, PIERRE VAN MOERBEKE, and DONG WANG. "RANDOM MATRIX MINOR PROCESSES RELATED TO PERCOLATION THEORY." Random Matrices: Theory and Applications 02, no. 04 (2013): 1350008. http://dx.doi.org/10.1142/s2010326313500081.

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This paper studies a number of matrix models of size n and the associated Markov chains for the eigenvalues of the models for consecutive n's. They are consecutive principal minors for two of the models, GUE with external source and the multiple Laguerre matrix model, and merely properly defined consecutive matrices for the third one, the Jacobi–Piñeiro model; nevertheless the eigenvalues of the consecutive models all interlace. We show: (i) For each of those finite models, we give the transition probability of the associated Markov chain and the joint distribution of the entire interlacing se

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Mondelli, M., A. Aretini, and A. Baldasseroni. "Distal Symmetric Polyneuropathy in Diabetes. Differences between Patients with and without Neuropathic Pain." Experimental and Clinical Endocrinology & Diabetes 120, no. 01 (2011): 45–50. http://dx.doi.org/10.1055/s-0031-1286296.

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AbstractTo demonstrate whether in distal symmetric polyneuropathy (DSPN) in diabetes there are differences between patients with and without neuropathic pain and whether pain is associated with demographic, clinical and electrophysiological variables.We prospectively enrolled 154 consecutive patients (mean age 67 years, 64% men) in an electromyography (EMG) lab. The differences were calculated between DSPN patients with (no.78) and without neuropathic pain (no.76) relating to age, sex, BMI, type, duration, treatment and complications of diabetes, HbA1c, type and duration of DSPN symptoms, DSPN

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Aenugu, Sneha, and David E. Huber. "Asymmetric Weights and Retrieval Practice in an Autoassociative Neural Network Model of Paired-Associate Learning." Neural Computation 33, no. 12 (2021): 3351–60. http://dx.doi.org/10.1162/neco_a_01444.

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Abstract Rizzuto and Kahana (2001) applied an autoassociative Hopfield network to a paired-associate word learning experiment in which (1) participants studied word pairs (e.g., ABSENCE-HOLLOW), (2) were tested in one direction (ABSENCE-?) on a first test, and (3) were tested in the same direction again or in the reverse direction (?-HOLLOW) on a second test. The model contained a correlation parameter to capture the dependence between forward versus backward learning between the two words of a word pair, revealing correlation values close to 1.0 for all participants, consistent with neural ne

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Yao, Zi-long, Qing-rong Lin, Yan-jun Hu, et al. "Interleukin-1 Beta Gene Polymorphism rs16944 May Associate with Increased Susceptibility to Extremity Chronic Osteomyelitis in Chinese Han Population." BioMed Research International 2019 (March 4, 2019): 1–9. http://dx.doi.org/10.1155/2019/7483537.

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Background. Previous studies had indicated that interleukin-1 beta (IL-1β) gene single nucleotide polymorphisms (SNPs) associate with different inflammatory diseases. However, potential links between these polymorphisms and susceptibility to extremity chronic osteomyelitis (COM) remain unclear. This study aimed to investigate relationships between IL-1β gene polymorphisms (rs16944, rs1143627, rs1143634, and rs2853550) and risks of developing extremity COM in Chinese Han population. Methods. Altogether 233 extremity COM patients and 200 healthy controls were genotyped for the four tag SNPs of t

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Althammer, Sonja, Amadís Pagès, and Eduardo Eyras. "Predictive Models of Gene Regulation from High-Throughput Epigenomics Data." Comparative and Functional Genomics 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/284786.

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The epigenetic regulation of gene expression involves multiple factors. The synergistic or antagonistic action of these factors has suggested the existence of an epigenetic code for gene regulation. Highthroughput sequencing (HTS) provides an opportunity to explore this code and to build quantitative models of gene regulation based on epigenetic differences between specific cellular conditions. We describe a new computational framework that facilitates the systematic integration of HTS epigenetic data. Our method relates epigenetic signals to expression by comparing two conditions. We show its

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Cheney, Karen L., Charlotta Skogh, Nathan S. Hart, and N. Justin Marshall. "Mimicry, colour forms and spectral sensitivity of the bluestriped fangblenny, Plagiotremus rhinorhynchos." Proceedings of the Royal Society B: Biological Sciences 276, no. 1662 (2009): 1565–73. http://dx.doi.org/10.1098/rspb.2008.1819.

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Animals change their body coloration for a variety of purposes including communication, thermoregulation and crypsis. The cues that trigger adaptive colour change are often unclear, and the role of colour vision remains largely untested. Here, we investigated the bluestriped fangblenny ( Plagiotremus rhinorhynchos ), an aggressive mimic that changes its body coloration to impersonate a variety of coral reef fishes. In this field, we determined the fish species that the fangblenny associated with and measured the spectral reflectance of mimics and their models. We measured the spectral absorban

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Jiang, Nan, Su-yi Li, Yun-fei Ma, Yan-jun Hu, Qing-rong Lin, and Bin Yu. "Associations between Interleukin Gene Polymorphisms and Risks of Developing Extremity Posttraumatic Osteomyelitis in Chinese Han Population." Mediators of Inflammation 2020 (May 5, 2020): 1–9. http://dx.doi.org/10.1155/2020/3278081.

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This case-control study aimed to investigate potential associations between interleukin (IL) gene polymorphisms and the risks of developing extremity posttraumatic osteomyelitis (PTOM) in Chinese Han population. Altogether, 189 PTOM patients and 200 healthy controls were genotyped of IL-1α (rs17561, rs1800587), IL-1β (rs16944, rs1143627, rs1143634, rs2853550), IL-1RN (rs4251961, rs419598, rs315951), IL-4 (rs2243248, rs2243250), IL-6 (rs1800795, rs1800796, rs1800797), IL-8 (rs4073, rs2227306, rs2227307), IL-10 (rs3024491, rs3024496, rs1800871, rs1800872, rs1800896), IL-17A (rs2275913), and IL-1

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De Vusser, Katrien, Dries Martens, Evelyne Lerut, Dirk Kuypers, Tim S. Nawrot, and Maarten Naesens. "Replicative senescence and arteriosclerosis after kidney transplantation." Nephrology Dialysis Transplantation 35, no. 11 (2020): 1984–95. http://dx.doi.org/10.1093/ndt/gfaa151.

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Abstract Background Replicative senescence is associated with telomere shortening. In native kidneys, obtained prior to transplantation, we recently described and validated a significant association between shorter intrarenal telomere length and renal arteriosclerosis. After renal transplantation, animal experiments suggested that ischaemia–reperfusion injury, acute rejection episodes and cytomegalovirus disease associate with accelerated renal allograft senescence. The association between post-transplant events and replicative senescence has not yet been evaluated in a human setting. Methods

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LUPERI, MAURICIO MARTINELLI. "The general equilibrium theory as economic metatheory." Revista de Economia Política 35, no. 2 (2015): 306–24. http://dx.doi.org/10.1590/0101-31572015v35n02a06.

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Many economists show certain nonconformity relative to the excessive mathematical formalization of economics. This stems from dissatisfaction with the old debate about the lack of correspondence between mainstream theoretical models and reality. Although we do not propose to settle this debate here, this article seeks to associate the mismatch of mathematized models with the reality of the adoption of the hypothetical-deductive method as reproduced by general equilibrium. We begin by defining the main benefits of the mathematization of economics. Secondly, we address traditional criticism leve

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Fiocco, Alexandra, Anik Obomsawin, and Danielle D'Amico. "THE ASSOCIATION BETWEEN MEDITERRANEAN DIET ADHERENCE AND ALLOSTATIC LOAD IN OLDER ADULTS." Innovation in Aging 6, Supplement_1 (2022): 353. http://dx.doi.org/10.1093/geroni/igac059.1395.

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Abstract Allostatic load (AL) is a multisystemic index of biological wear and tear which is associated with poor health outcomes. In recent years, researchers have examined the association between dietary pattern intake and AL; however, no studies to date have examined the relationship between AL and consumption of a Mediterranean diet. Blood and urine samples were collected from 201 community-dwelling older adults who completed a Food Frequency Questionnaire (FFQ). A Mediterranean Diet Score (MDS) was calculated based on previous recommendations and a sex-based AL index was calculated using a

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Manju, Sapkota. "Factor Influncing the Demand of Life Insurance Policy." Journal of Corporate Finance Management and Banking System, no. 42 (February 1, 2024): 25–34. http://dx.doi.org/10.55529/jcfmbs.42.25.34.

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This paper aims to investigate factors influencing life insurance purchase and what factors significantly affect customers towards the purchase of life insurance policies in Rupandehi district. Primary data have been collected through structured questionnaire out of 350 life insurance policyholder’s resident of Rupandehi district of Nepal. Sample was selected by Convenience sampling method. The paper has used regression models to analyze the relationship between dependent and independent variable. The result of the study reveals that level of education, age factor and people attitude and aware

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Svoboda, Steven J., Brett D. Owens, Travis M. Harvey, Patrick M. Tarwater, William F. Brechue, and Kenneth L. Cameron. "The Association Between Serum Biomarkers of Collagen Turnover and Subsequent Anterior Cruciate Ligament Rupture." American Journal of Sports Medicine 44, no. 7 (2016): 1687–93. http://dx.doi.org/10.1177/0363546516640515.

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Background: No study has attempted to associate the levels of preinjury serum biomarkers of collagen turnover with the subsequent risk of anterior cruciate ligament (ACL) injury. Hypothesis: Preinjury serum biomarkers of collagen turnover would be associated with the subsequent risk of ACL injury. Study Design: Case-control study; Level of evidence, 3. Methods: We conducted a case-control study with 45 ACL-injured cases and 45 controls matched for sex, age, height, and weight. In addition to the matching criteria, controls had no history of major joint injury. Baseline preinjury serum samples

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Yoo, Yong-Sang, Seong-Ho Lee, and Seung-Hwan Bae. "Effective Multi-Object Tracking via Global Object Models and Object Constraint Learning." Sensors 22, no. 20 (2022): 7943. http://dx.doi.org/10.3390/s22207943.

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Effective multi-object tracking is still challenging due to the trade-off between tracking accuracy and speed. Because the recent multi-object tracking (MOT) methods leverage object appearance and motion models so as to associate detections between consecutive frames, the key for effective multi-object tracking is to reduce the computational complexity of learning both models. To this end, this work proposes global appearance and motion models to discriminate multiple objects instead of learning local object-specific models. In concrete detail, it learns a global appearance model using contras

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DŽAMONJA, MIRNA, and JOUKO VÄÄNÄNEN. "CHAIN MODELS, TREES OF SINGULAR CARDINALITY AND DYNAMIC EF-GAMES." Journal of Mathematical Logic 11, no. 01 (2011): 61–85. http://dx.doi.org/10.1142/s0219061311001006.

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Let κ be a singular cardinal. Karp's notion of a chain model of size κ is defined to be an ordinary model of size κ along with a decomposition of it into an increasing union of length cf (κ). With a notion of satisfaction and (chain)-isomorphism such models give an infinitary logic largely mimicking first order logic. In this paper we associate to this logic a notion of a dynamic EF-game which gauges when two chain models are chain-isomorphic. To this game is associated a tree which is a tree of size κ with no κ-branches (even no cf (κ)-branches). The measure of how non-isomorphic the models a

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Szupera, Zoltán, György Czifra, Bence Fülöp, et al. "Association between angiotensin receptor blocker therapy and acute seizures in patients with stroke." Ideggyógyászati szemle 78, no. 1-2 (2025): 47–55. https://doi.org/10.18071/isz.78.0047.

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Background and purpose – There are some new results that the angiotensin receptor blockers (ARB) therapy may associate with a lower risk of epilepsy. However, its pathomechanism and the patient characteristics are lacking. We asses, whether ARB therapy is associates with lower incidence of acute symptomatic seizures, compared with no ARB therapy in patients with acute stroke. Methods – There was a single-center, retrospective, observational cross-sectional study, enrolled patients with acute stroke admitted to our hospital, from 1 January 2019 to 31 December 2021. The data source was our hospi

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Deleyrolle, Loic, Jeffrey Harrison, Gregory Takacs, and Matthew Sarkisian. "TMIC-32. TUMOR CELL CILIA ASSOCIATE WITH SPECIFIC IMMUNE CELL POPULATIONS IN HUMAN AND MOUSE MODELS OF GBM." Neuro-Oncology 24, Supplement_7 (2022): vii278. http://dx.doi.org/10.1093/neuonc/noac209.1076.

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Abstract INTRODUCTION Glioblastoma (GBM) typically recurs after standard of care therapies. A major obstacle is that GBMs employ various mechanisms to suppress the host immune system, preventing destruction and removal of cancer cells. A better understanding of the crosstalk mechanisms between tumor and immune cell types is needed to advance immunotherapeutic approaches against GBM. GBMs contain primary cilia, organelles likened to both cellular ‘antennae’ and transmitters, and their presence is associated with more aggressive and treatment resistant tumors. OBJECTIVE To explore whether ciliat

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Loprinzi, Paul D. "Physical Activity With Alanine Aminotransferase and Gamma-Glutamyltransferase: Implications of Liver Pathology on the Relationship Between Physical Activity and Mortality." Journal of Physical Activity and Health 13, no. 9 (2016): 988–92. http://dx.doi.org/10.1123/jpah.2015-0688.

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Objective:Examine the association between objectively-measured moderate-to-vigorous physical activity (MVPA) and engagement in self-reported muscle strengthening activities (MSA) with alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT), and in turn, how each of these parameters associate with of all-cause mortality.Methods:Data from the 2003–2006 NHANES were employed, with follow-up through December 31, 2011 (N = 5030; 20+ yrs). Physical activity was assessed via accelerometry; MSA was assessed via survey; and ALT and GGT were assessed via a blood sample. Linear regression and C

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Shvabskaia, O. B., N. S. Karamnova, O. V. Izmailova, and O. M. Drapkina. "Healthy Eating in Population Models of Nutrition: Asian Diet Style Summary." Rational Pharmacotherapy in Cardiology 18, no. 6 (2023): 692–702. http://dx.doi.org/10.20996/1819-6446-2022-12-08.

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The population of Japan and Okinawa is known for the longest life expectancy, which many researchers rightly associate with the nature of nutrition existing in these territories. The Japanese diet and Okinawan diet, along with other traditional diets, are real examples of historically established sustainable patterns of healthy eating. Asian eating styles have marked differences from European eating patterns, not only in differences in food sources, but also in eating habits. The article presents the historical, climatic and cultural features of these diets; the issues of food composition, ene

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Terrer, César, Sara Vicca, Bruce A. Hungate, Richard P. Phillips, and I. Colin Prentice. "Mycorrhizal association as a primary control of the CO2 fertilization effect." Science 353, no. 6294 (2016): 72–74. http://dx.doi.org/10.1126/science.aaf4610.

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Plants buffer increasing atmospheric carbon dioxide (CO2) concentrations through enhanced growth, but the question whether nitrogen availability constrains the magnitude of this ecosystem service remains unresolved. Synthesizing experiments from around the world, we show that CO2 fertilization is best explained by a simple interaction between nitrogen availability and mycorrhizal association. Plant species that associate with ectomycorrhizal fungi show a strong biomass increase (30 ± 3%, P < 0.001) in response to elevated CO2 regardless of nitrogen availability, whereas low nitrogen availab

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Pinthus, Jehonathan H., Sarah Hopmans, Geoff Werstuck, and Wilhelmina CM Duivenvoorden. "The role of FSH in castration-induced adipogenesis and cardiovascular diseases: Highlighting differences between orchiectomy, GNRH agonists, and antagonists." Journal of Clinical Oncology 32, no. 4_suppl (2014): 191. http://dx.doi.org/10.1200/jco.2014.32.4_suppl.191.

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191 Background: Androgen deprivation therapy (ADT) is associated with weight gain and development of the metabolic syndrome (MS). Different modes of ADT can achieve castration but with different affects on serum FSH levels. Inspired by the observation that adiposity accompanies the incremental increase in serum follicle stimulating hormone (FSH) levels in menopause, we hypothesized that gonadotrophin-releasing hormone (GnRH) antagonists which maximally inhibit FSH levels will associate with reduced adiposity and MS development compared to GNRH analogues and orchiectomy. Methods: In-vitro model

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Prokop, J. W., and C. F. Deschepper. "Chromosome Y genetic variants: impact in animal models and on human disease." Physiological Genomics 47, no. 11 (2015): 525–37. http://dx.doi.org/10.1152/physiolgenomics.00074.2015.

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Chromosome Y (chrY) variation has been associated with many complex diseases ranging from cancer to cardiovascular disorders. Functional roles of chrY genes outside of testes are suggested by the fact that they are broadly expressed in many other tissues and correspond to regulators of basic cellular functions (such as transcription, translation, and protein stability). However, the unique genetic properties of chrY (including the lack of meiotic crossover and the presence of numerous highly repetitive sequences) have made the identification of causal variants very difficult. Despite the prior

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Tebbe, Lars, Mashal Kakakhel, Mustafa S. Makia, Muayyad R. Al-Ubaidi, and Muna I. Naash. "The Interplay between Peripherin 2 Complex Formation and Degenerative Retinal Diseases." Cells 9, no. 3 (2020): 784. http://dx.doi.org/10.3390/cells9030784.

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Peripherin 2 (Prph2) is a photoreceptor-specific tetraspanin protein present in the outer segment (OS) rims of rod and cone photoreceptors. It shares many common features with other tetraspanins, including a large intradiscal loop which contains several cysteines. This loop enables Prph2 to associate with itself to form homo-oligomers or with its homologue, rod outer segment membrane protein 1 (Rom1) to form hetero-tetramers and hetero-octamers. Mutations in PRPH2 cause a multitude of retinal diseases including autosomal dominant retinitis pigmentosa (RP) or cone dominant macular dystrophies.

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Chaouiya, Claudine, Sarah M. Keating, Duncan Berenguier, et al. "SBML Level 3 package: Qualitative Models, Version 1, Release 1." Journal of Integrative Bioinformatics 12, no. 2 (2015): 691–730. http://dx.doi.org/10.1515/jib-2015-270.

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Summary Quantitative methods for modelling biological networks require an in-depth knowledge of the biochemical reactions and their stoichiometric and kinetic parameters. In many practical cases, this knowledge is missing. This has led to the development of several qualitative modelling methods using information such as, for example, gene expression data coming from functional genomic experiments. The SBML Level 3 Version 1 Core specification does not provide a mechanism for explicitly encoding qualitative models, but it does provide a mechanism for SBML packages to extend the Core specificati

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Meyer, Kylie, Sara Masoud, Ashlie Glassner, et al. "13623 Daily relationship between social connectedness and health behaviors among dementia family caregivers." Journal of Clinical and Translational Science 5, s1 (2021): 97–98. http://dx.doi.org/10.1017/cts.2021.651.

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ABSTRACT IMPACT: Knowledge of which aspects of social connectedness most strongly associate with caregiver health and health behaviors can inform intervention targets to improve caregiver health OBJECTIVES/GOALS: Stressed dementia caregivers are at risk of poor health. Social connectedness may reduce adverse health effects, yet it is unknown about which aspects relate most strongly to health. This is a barrier to intervention development. Our study identifies aspects of social connectedness most strongly associate with caregivers’ daily health behaviors. METHODS/STUDY POPULATION: Data. Enrolle

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Zhang, M., X. Xiao, D. Xiong, and Q. Liu. "Topic-Based Dissimilarity and Sensitivity Models for Translation Rule Selection." Journal of Artificial Intelligence Research 50 (May 8, 2014): 1–30. http://dx.doi.org/10.1613/jair.4265.

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Translation rule selection is a task of selecting appropriate translation rules for an ambiguous source-language segment. As translation ambiguities are pervasive in statistical machine translation, we introduce two topic-based models for translation rule selection which incorporates global topic information into translation disambiguation. We associate each synchronous translation rule with source- and target-side topic distributions.With these topic distributions, we propose a topic dissimilarity model to select desirable (less dissimilar) rules by imposing penalties for rules with a large v

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Sokol, Emily, Warner Myntti, Jenna Walters, Maisy Seale, and Chong Man Chow. "Emotion dysregulation and eating disorder symptoms in mother-daughter dyads: An actor-partner interdependence modeling approach." Journal of Social and Clinical Psychology 43, no. 6 (2024): 583–604. https://doi.org/10.1521/jscp.2024.43.6.583.

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Introduction: This study investigates dyadic associations between emotion dysregulation and eating disorder symptoms in mother-daughter dyads. This study employs the Actor-Partner Interdependence Model (APIM) to test three hypotheses: (1) emotion dysregulation will associate with an individual's own eating disorder risk beyond the effect of their partner's emotional dysregulation (actor effect); (2) emotion dysregulation will associate with a dyad member's eating disorder risk beyond the effect of their emotion dysregulation (partner effect); (3) dyad members’ emotional dysregulation will inte

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Bos, Maxime M., Diana van Heemst, Esther Donga, et al. "The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses." Journal of Clinical Medicine 8, no. 5 (2019): 682. http://dx.doi.org/10.3390/jcm8050682.

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Evidence on whether habitual sleep duration and sleep quality are associated with increased insulin resistance is inconsistent. Here, we investigated the associations between different measures of habitual sleep with glycemic traits through cross-sectional and Mendelian randomization (MR) analyses. We assessed the associations of sleep duration and sleep quality with glycemic traits using multivariable linear regression models adjusted for potential confounders in 4672 middle-aged (45–65 years; 48% men) nondiabetic participants of the Netherlands Epidemiology of Obesity (NEO) study. Genetic va

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Vitobello, Antonio, Juliane Perner, Johanna Beil, et al. "Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion." Life Science Alliance 2, no. 5 (2019): e201900461. http://dx.doi.org/10.26508/lsa.201900461.

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Liver cancer susceptibility varies amongst humans and between experimental animal models because of multiple genetic and epigenetic factors. The molecular characterization of such susceptibilities has the potential to enhance cancer risk assessment of xenobiotic exposures and disease prevention strategies. Here, using DNase I hypersensitivity mapping coupled with transcriptomic profiling, we investigate perturbations in cis-acting gene regulatory elements associated with the early stages of phenobarbital (PB)-mediated liver tumor promotion in susceptible versus resistant mouse strains (B6C3F1

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Abdullah, Sheikh S., Neda Rostamzadeh, Kamran Sedig, Amit X. Garg, and Eric McArthur. "Multiple Regression Analysis and Frequent Itemset Mining of Electronic Medical Records: A Visual Analytics Approach Using VISA_M3R3." Data 5, no. 2 (2020): 33. http://dx.doi.org/10.3390/data5020033.

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Medication-induced acute kidney injury (AKI) is a well-known problem in clinical medicine. This paper reports the first development of a visual analytics (VA) system that examines how different medications associate with AKI. In this paper, we introduce and describe VISA_M3R3, a VA system designed to assist healthcare researchers in identifying medications and medication combinations that associate with a higher risk of AKI using electronic medical records (EMRs). By integrating multiple regression models, frequent itemset mining, data visualization, and human-data interaction mechanisms, VISA

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Avram, Florin, Rim Adenane, and David I. Ketcheson. "A Review of Matrix SIR Arino Epidemic Models." Mathematics 9, no. 13 (2021): 1513. http://dx.doi.org/10.3390/math9131513.

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Many of the models used nowadays in mathematical epidemiology, in particular in COVID-19 research, belong to a certain subclass of compartmental models whose classes may be divided into three “(x,y,z)” groups, which we will call respectively “susceptible/entrance, diseased, and output” (in the classic SIR case, there is only one class of each type). Roughly, the ODE dynamics of these models contains only linear terms, with the exception of products between x and y terms. It has long been noticed that the reproduction number R has a very simple Formula in terms of the matrices which define the

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Similä, Minna E., Jukka P. Kontto, Satu Männistö, Liisa M. Valsta, and Jarmo Virtamo. "Glycaemic index, carbohydrate substitution for fat and risk of CHD in men." British Journal of Nutrition 110, no. 9 (2013): 1704–11. http://dx.doi.org/10.1017/s0007114513000858.

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We have examined the associations between dietary glycaemic index (GI), substitutions of total, low-, medium- and high-GI carbohydrates for fat and the risk of CHD. The study consisted of 21 955 male smokers, aged 50–69 years, within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. The diet was assessed at baseline using a validated FFQ. During a 19-year follow-up, 4379 CHD cases (2377 non-fatal myocardial infarctions and 2002 CHD deaths) were identified from national registers. Relative risks (RR) and CI for CHD were analysed using Cox proportional hazards modelling, and multivari

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Vardakas, John S., Nizar Zorba, and Christos Verikoukis. "Scheduling Policies for Two-State Smart-Home Appliances in Dynamic Electricity Pricing Environments." Energy 69, no. 1 (2014): 455–69. https://doi.org/10.1016/j.energy.2014.03.037.

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In this paper we present and analyze online and offline scheduling models for the determination of the maximum power consumption in a smart grid environment. The proposed load models consider that each consumer's residence is equipped with a certain number of appliances of different power demands and different operational times, while the appliances' feature of alternating between ON and OFF states is also incorporated. Each load model is correlated with a scheduling policy that aims to the reduction of the power consumption through the compression of power demands or the postponement of power

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Ouyang, Huei-Tau. "Multi-objective optimization of typhoon inundation forecast models with cross-site structures for a water-level gauging network by integrating ARMAX with a genetic algorithm." Natural Hazards and Earth System Sciences 16, no. 8 (2016): 1897–909. http://dx.doi.org/10.5194/nhess-16-1897-2016.

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Abstract. The forecasting of inundation levels during typhoons requires that multiple objectives be taken into account, including the forecasting capacity with regard to variations in water level throughout the entire weather event, the accuracy that can be attained in forecasting peak water levels, and the time at which peak water levels are likely to occur. This paper proposed a means of forecasting inundation levels in real time using monitoring data from a water-level gauging network. ARMAX was used to construct water-level forecast models for each gauging station using input variables inc

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Broughton, Adam, Alexis Landry, Mary Showstark, et al. "Military Veteran Matriculation in US Physician Associate/Assistant Programs." Journal of Physician Assistant Education, January 16, 2024. http://dx.doi.org/10.1097/jpa.0000000000000568.

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Objectives This study aims to determine whether veterans have differential access to physician associate/assistant (PA) education by examining likelihood of matriculation relative to nonveteran peers. We explore associations between veteran status and likelihood of matriculation for change over time and whether effects differ among active duty versus non–active-duty applicants. Methods Multivariate logistic regression was used to investigate associations between self-identified military status and likelihood of PA program matriculation in five Centralized Applicant Services for Physician Assis

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Kaplow, Irene M., Alyssa J. Lawler, Daniel E. Schäffer, et al. "Relating enhancer genetic variation across mammals to complex phenotypes using machine learning." Science 380, no. 6643 (2023). http://dx.doi.org/10.1126/science.abm7993.

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Protein-coding differences between species often fail to explain phenotypic diversity, suggesting the involvement of genomic elements that regulate gene expression such as enhancers. Identifying associations between enhancers and phenotypes is challenging because enhancer activity can be tissue-dependent and functionally conserved despite low sequence conservation. We developed the Tissue-Aware Conservation Inference Toolkit (TACIT) to associate candidate enhancers with species’ phenotypes using predictions from machine learning models trained on specific tissues. Applying TACIT to associate m

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VandeBunte, Anna M., Bailey L. Ortiz, Emily W. Paolillo, et al. "Molecular correlates of neural health associate with cardiovascular states." Alzheimer's & Dementia 20, S8 (2024). https://doi.org/10.1002/alz.094632.

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AbstractBackgroundSuboptimal cardiovascular health poses a significant risk for dementia, yet biological links between cardiovascular health and brain function are poorly understood. We examined how plasma markers of astrocytic activation (GFAP), neuronal axon breakdown (NfL), and Alzheimer’s disease (AD) pathology (pTau181) relate to several behavioral and risk indicators of systemic cardiovascular health in older adults along the AD continuum.Method209 older adults (59% female; 88% clinically normal; 15% amyloid PET+) completed 30‐day FitbitTM Flex2 monitoring (average daily steps), blood pr

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Peregud, Danil I., Valeria Yu Baronets, Anna S. Lobacheva, et al. "Relationship between BDNF gene polymorphisms and alcohol-related liver cirrhosis." Egyptian Liver Journal 13, no. 1 (2023). http://dx.doi.org/10.1186/s43066-023-00296-2.

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Abstract Background and aim Brain-derived neurotrophic factor (BDNF) functions not only in the brain but also in peripheral tissues such as the liver. Genetic factors determine the development of alcohol dependence and somatic consequences of chronic intoxication, especially liver cirrhosis. The BDNF gene polymorphisms are associated with alcohol dependence; however, their relationship with the development of alcohol-related liver cirrhosis (ALC) has not yet been established. This study evaluated the association between single-nucleotide polymorphisms (SNPs) within the BDNF gene and liver cirr

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Vepsäläinen, Henna, Liisa Korkalo, Essi Skaffari, et al. "How energy balance-related behaviors, temperament, stress, and overweight associate: A cross-sectional study of Finnish preschoolers." Public Health Nutrition, March 4, 2024, 1–30. http://dx.doi.org/10.1017/s1368980024000612.

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Abstract Objective: This study aimed to 1) examine the clustering of energy balance-related behaviors (EBRBs) and 2) investigate whether EBRB clusters, temperament, and hair cortisol concentration (HCC) associate with overweight. Design: We assessed food consumption using food records, screen time using sedentary behavior diaries, sleep consistency and temperament (negative affectivity, surgency, effortful control) using questionnaires, and HCC using hair samples. Accelerometers were used to assess physical activity (PA) intensities, sleep duration, and sleep efficiency. Researchers measured e

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Franses, Philip Hans. "Do China's Loans Associate With Economic Growth in Africa?" Review of Development Economics, May 13, 2025. https://doi.org/10.1111/rode.13252.

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ABSTRACTThis paper considers various econometric models to estimate the potential link between Chinese loans to African countries and economic growth measured by growth in real Gross Domestic Product (GDP). The overall conclusion is that the association of loans with economic growth in Africa is small and heterogeneous. For some countries, like Eritrea, the associations are positive and large, but for others like Chad and Rwanda, the associations are large and negative. For most countries, we cannot conclude that countries which receive Chinese loans grow faster.

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Betzios, P., and O. Papadoulaki. "Liouville theory and matrix models: a Wheeler DeWitt perspective." Journal of High Energy Physics 2020, no. 9 (2020). http://dx.doi.org/10.1007/jhep09(2020)125.

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Abstract We analyse the connections between the Wheeler DeWitt approach for two dimensional quantum gravity and holography, focusing mainly in the case of Liouville theory coupled to c = 1 matter. Our motivation is to understand whether some form of averaging is essential for the boundary theory, if we wish to describe the bulk quantum gravity path integral of this two dimensional example. The analysis hence, is in a spirit similar to the recent studies of Jackiw-Teitelboim (JT)-gravity. Macroscopic loop operators define the asymptotic region on which the holographic boundary dual resides. Mat

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