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Journal articles on the topic 'Astatide'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Garkushin, Ivan K., Olga V. Lavrenteva, Yana A. Andreeva, and Karina R. Gilmanova. "Analytical description of the specific electric conductivity of halogenides KHal melts and its calculation for the KAt melt." Butlerov Communications 58, no. 6 (2019): 138–45. http://dx.doi.org/10.37952/roi-jbc-01/19-58-6-138.

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In this paper, the analytical description of the specific conductivity of the potassium halogenides melts KHal (Hal – F, Cl, Br, I) is presented. The analitical description is provided on dependence of the specific conductivity on the halogen order number ӕ = f(Z), the ionic radius of halogen-ion ӕ = f(r), the ionic potential ӕ = f(1/r), the electronegativity difference ӕ = f(∆χ) ((∆χ = χ (Hal) – χ(K)). The interrelation of a reduced property with an order number ӕ/Z = f(Z) is considered. According to the obtained analytical dependencies, the calculation of the value of the potassium astatide

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2

Baran, Enrique J. "Vibrational Properties of Hydrogen Astatide, HAt." Zeitschrift für Naturforschung A 59, no. 3 (2004): 133–35. http://dx.doi.org/10.1515/zna-2004-0306.

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A number of theoretical studies on the bond characteristics of HAt, the heaviest hydrogen halide, have recently been reported. On the basis of these data the force constant, mean amplitudes of vibration and thermodynamic functions of this molecule have been calculated. Some comparisons with the related lighter hydracids are made.

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3

Pruszyński, M., A. Bilewicz, B. Wąs, and B. Petelenz. "Formation and stability of astatide-mercury complexes." Journal of Radioanalytical and Nuclear Chemistry 268, no. 1 (2006): 91–94. http://dx.doi.org/10.1007/s10967-006-0129-2.

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4

Wilbur, D. "[211At]Astatine-Labeled Compound Stability: Issues with Released [211At]Astatide and Development of Labeling Reagents to Increase Stability." Current Radiopharmaceuticalse 1, no. 3 (2008): 144–76. http://dx.doi.org/10.2174/1874471010801030144.

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5

Styszyński, Jacek, and Jacek Kobus. "Relativistic and correlation effects on spectroscopic constants of the hydrogen astatide molecule." Chemical Physics Letters 369, no. 3-4 (2003): 441–48. http://dx.doi.org/10.1016/s0009-2614(02)02014-6.

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6

Larsen, Roy H., Susan Slade, and Michael R. Zalutsky. "Blocking [211At]Astatide Accumulation in Normal Tissues: Preliminary Evaluation of Seven Potential Compounds." Nuclear Medicine and Biology 25, no. 4 (1998): 351–57. http://dx.doi.org/10.1016/s0969-8051(97)00230-8.

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7

Carlin, Sean, Robert J. Mairs, Phil Welsh, and Michael R. Zalutsky. "Sodium-iodide symporter (NIS)-mediated accumulation of [211At]astatide in NIS-transfected human cancer cells." Nuclear Medicine and Biology 29, no. 7 (2002): 729–39. http://dx.doi.org/10.1016/s0969-8051(02)00332-3.

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8

Garkushin, Ivan K., Olga V. Lavrenteva, Karina R. Gilmanova, and Yana A. Andreeva. "Analytical description of sodium halogenides melts specific electric conductivity and its calculation for sodium astatide melt." Butlerov Communications 60, no. 12 (2019): 125–32. http://dx.doi.org/10.37952/roi-jbc-01/19-60-12-125.

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The paper presents analytical and graphical dependences of the individual haloganides melts specific electrical conductivity æ of the sodium NaHal series (Hal – F, Cl, Br, I) on the halogen order number Z, ionic radius r of haloganide-ion Hal–, halogen ionic potential 1/r, reduced ionic radius r/Z, difference of electronegativity (∆χ = χ(Hal) – χ(Na)): æ = f(Z); æ = f(r); æ = f(1/r); æ = f(r/Z); æ = f(∆χ) for the temperature higher melting temperatures on 5, 10, 50, 75, 100, 150 и 200°. M.Kh. Karapetyans сomparative methods were applied for the description. The minimum standard deviation and m

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9

Watabe, Tadashi, Makoto Hosono, Seigo Kinuya, et al. "Manual on the proper use of sodium astatide ([211At]NaAt) injections in clinical trials for targeted alpha therapy (1st edition)." Annals of Nuclear Medicine 35, no. 7 (2021): 753–66. http://dx.doi.org/10.1007/s12149-021-01619-2.

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AbstractWe present the guideline for use of [211At] sodium astatide (NaAt) for targeted alpha therapy in clinical trials on the basis of radiation safety issues in Japan. This guideline was prepared by a study supported by the Ministry of Health, Labour, and Welfare, and approved by the Japanese Society of Nuclear Medicine on 8th Feb, 2021. The study showed that patients receiving [211At]NaAt do not need to be admitted to a radiotherapy room and outpatient treatment is possible. The radiation exposure from the patient is within the safety standards of the ICRP and IAEA recommendations for the

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10

Rimár, Miroslav, Marcel Fedák, and Štefan Kuna. "Equation Model of Stabilization of Low Damped Astatic Systems." Applied Mechanics and Materials 415 (September 2013): 427–30. http://dx.doi.org/10.4028/www.scientific.net/amm.415.427.

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The paper deals with the stabilization of low damped astatic systems. They show a low value of a relative damping and consequently a high resonance rise of amplitude frequency response. If astatism occurs in an automatic control system, the situation becomes complicated due to the exhaustion of a phase safety of astatic element. In order to achieve the stabilization, a filter with rejections has been designed. The filter is characterized by rapid rejections of logarithmic frequency characteristics that eliminate resonance rise of a low damped astatic system. A functional model of a discrete fi

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11

Kaneda-Nakashima, Kazuko, Yoshifumi Shirakami, Tadashi Watabe, et al. "Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter." International Journal of Molecular Sciences 23, no. 24 (2022): 15509. http://dx.doi.org/10.3390/ijms232415509.

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This study confirmed the effect of sodium/iodine symporter (NIS) expression on existing drugs by in vitro and in vivo tests using cultured cell lines. The tumor growth inhibitory effect of sodium astatide ([211At]NaAt) was evaluated by in vitro and in vivo tests using human thyroid cancer cells (K1, K1/NIS and K1/NIS-DOX). NIS expression in cancer cells was controlled using the Tet-On system. [131I]NaI was used as control existing drug. From the results of the in vitro studies, the mechanism of [211At]NaAt uptake into thyroid cancer cells is mediated by NIS, analogous to [131I]NaI, and the cel

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12

Tkachuk, A., O. Bezvesilna, I. Kryzhanivska, and M. Bogdanovsky. "FEATURES OF CONTROLLING AN ASTATIC OBJECT OF THE THIRD ORDER." Scientific heritage, no. 142 (August 7, 2024): 58–61. https://doi.org/10.5281/zenodo.13252977.

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The article examines the process of designing automatic control systems and analyzes its main stages. The most common regulatory laws and regulators built on their basis are described. The process of selecting a regulator and the method of calculating its setting parameters for controlling a third-order astatic object with an order of astatism equal to one are considered. It is shown that a high-quality control process is ensured by using the proportional-differential control law.

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13

McLendon, Roger E., Gerald E. Archer, Pradeep K. Garg, Darell D. Bigner, and Michael R. Zalutsky. "Radiotoxicity of systemically administered [211At]astatide in B6C3F1 and BALB/c (nu/nu) mice: A long-term survival study with histologic analysis." International Journal of Radiation Oncology*Biology*Physics 35, no. 1 (1996): 69–80. http://dx.doi.org/10.1016/s0360-3016(96)85013-9.

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14

Gnezdov, Nikolay, Aleksey Kolganov, and Sergey Lebedev. "Application of Astatic State Observers in Electromechanotronic Modules." Scientific Journal of Riga Technical University. Power and Electrical Engineering 27, no. 1 (2010): 152–55. http://dx.doi.org/10.2478/v10144-010-0039-6.

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Application of Astatic State Observers in Electromechanotronic ModulesThe authors offer a synthesis method of state observers with high-order astatism. There are no errors caused by the action of arbitrary external disturbances in reduced variables of such observers. The observers also restore the instantaneous values of disturbances. The authors present a calculation method of ultimate realizable dynamics of observers during their realization in microprocessor control system which calculates in numbers with fixed point without overflowing of variables. The description of experimental installa

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15

Li, Yawen, Ming-Kuan Chyan, Donald K. Hamlin, Holly Nguyen, Eva Corey, and D. Scott Wilbur. "Oxidation of p-[125I]Iodobenzoic Acid and p-[211At]Astatobenzoic Acid Derivatives and Evaluation In Vivo." International Journal of Molecular Sciences 23, no. 18 (2022): 10655. http://dx.doi.org/10.3390/ijms231810655.

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The alpha particle-emitting radionuclide astatine-211 (211At) is of interest for targeted radiotherapy; however, low in vivo stability of many 211At-labeled cancer-targeting molecules has limited its potential. As an alternative labeling method, we evaluated whether a specific type of astatinated aryl compound that has the At atom in a higher oxidation state might be stable to in vivo deastatination. In the research effort, para-iodobenzoic acid methyl ester and dPEG4-amino acid methyl ester derivatives were prepared as HPLC standards. The corresponding para-stannylbenzoic acid derivatives wer

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16

Nagao, Y., M. Yamaguchi, S. Watanabe, N. S. Ishioka, N. Kawachi, and H. Watabe. "Performance improvement of Compton imaging of astatine-211 by optimising coincidence time windows." Journal of Instrumentation 16, no. 12 (2021): C12031. http://dx.doi.org/10.1088/1748-0221/16/12/c12031.

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Abstract Astatine-211 is one of the promising radioisotopes for targeted alpha therapy. Optimising treatment strategies as well as determining the suitability of a given agent for a particular patient requires to image the time-dependent distribution of the targeted radiotherapeutic agent both in tumours and in normal tissues. Since the biodistribution of astatine is different from that of iodine, imaging astatine-211 directly is essential. In the previous study of astatine-211 Compton imaging, random coincidence events due to polonium K-shell X-rays were dominant and seemed to cause saturatio

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17

CORSON, DALE R. "ASTATINE." Chemical & Engineering News 81, no. 36 (2003): 158. http://dx.doi.org/10.1021/cen-v081n036.p158.

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18

Meyer, Geerd-J. "Astatine." Journal of Labelled Compounds and Radiopharmaceuticals 61, no. 3 (2018): 154–64. http://dx.doi.org/10.1002/jlcr.3573.

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19

Wilbur, D. Scott. "Enigmatic astatine." Nature Chemistry 5, no. 3 (2013): 246. http://dx.doi.org/10.1038/nchem.1580.

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20

Aneheim, Emma, Tom Bäck, Holger Jensen, Stig Palm, and Sture Lindegren. "A proposed production method for astatinated (At-211) Trastuzumab for use in a Phase I clinical trial." PLOS ONE 19, no. 9 (2024): e0307543. http://dx.doi.org/10.1371/journal.pone.0307543.

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Astatine-211 is a nuclide with a short half-life of 7.2 h, that show promise for targeted alpha therapy of disseminated cancer. Despite nuclide production being straight-forward using a medium energy cyclotron and an uncomplicated target, not many cyclotrons are currently producing the nuclide. In this work we propose a stream-lined method to produce astatine labelled antibodies that enable production of clinical doses at other sites, remote from the nuclide producing cyclotron. Preconjugating the antibody prior to labelling, quick and efficient astatine recovery from the irradiated target in

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21

Takashima, Hiroki, Shino Manabe, Ryo Tsumura, et al. "Abstract 4344: Broader therapeutic window via combining sodium ascorbate for protecting radioactive antibodies from radiolysis and sodium perchlorate for blocking sodium iodide symporter in radioimmunotherapy with astatine-211." Cancer Research 85, no. 8_Supplement_1 (2025): 4344. https://doi.org/10.1158/1538-7445.am2025-4344.

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Background: Increasing attention has been paid to developing new cancer treatments with alpha particles characterized by a high linear energy transfer (LET) and a range of 50-100 µm in tissue, which is equivalent to 5-10 cells. Due to the short path length, tumor-selective accumulation of alpha particles is pivotal for achieving a reasonable therapeutic window. Previously, we demonstrated that reactive oxygen species (ROS) generated via the radiolysis of water in storage solution denature antibodies labeled with astatine-211, an alpha emitter, which results in disrupted specific binding activi

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22

Sarr, Serigne, Julien Pilmé, Gilles Montavon, Jean-Yves Le Questel, and Nicolas Galland. "Astatine Facing Janus: Halogen Bonding vs. Charge-Shift Bonding." Molecules 26, no. 15 (2021): 4568. http://dx.doi.org/10.3390/molecules26154568.

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The nature of halogen-bond interactions was scrutinized from the perspective of astatine, potentially the strongest halogen-bond donor atom. In addition to its remarkable electronic properties (e.g., its higher aromaticity compared to benzene), C6At6 can be involved as a halogen-bond donor and acceptor. Two-component relativistic calculations and quantum chemical topology analyses were performed on C6At6 and its complexes as well as on their iodinated analogues for comparative purposes. The relativistic spin–orbit interaction was used as a tool to disclose the bonding patterns and the mechanis

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23

Yagishita, Atsushi, Miho Katsuragawa, Shin’ichiro Takeda, et al. "Development and Utility of an Imaging System for Internal Dosimetry of Astatine-211 in Mice." Bioengineering 11, no. 1 (2023): 25. http://dx.doi.org/10.3390/bioengineering11010025.

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In targeted radionuclide therapy, determining the absorbed dose of the ligand distributed to the whole body is vital due to its direct influence on therapeutic and adverse effects. However, many targeted alpha therapy drugs present challenges for in vivo quantitative imaging. To address this issue, we developed a planar imaging system equipped with a cadmium telluride semiconductor detector that offers high energy resolution. This system also comprised a 3D-printed tungsten collimator optimized for high sensitivity to astatine-211, an alpha-emitting radionuclide, and adequate spatial resolutio

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24

Dzhuzha, D., and S. Myasoyedov. "Radionuclide therapy with alpha-emitters." Radiation Diagnostics, Radiation Therapy, no. 4 (2019): 37–47. http://dx.doi.org/10.37336/2707-0700-2019-4-4.

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In this review the main streams of using alpha-emitters radium-223, actinium-225, bismuth-213, astatine-211 in complex treatment of malignant tumors are reviewed. The features of radiobiological actions of alpha-emission make its more effective in hundred times than beta-emission. The efficacy of this kind of radionuclide therapy does not dependent from chemoresistance and radioresistance to beta-emitters. The results of experimental and initial clinical investigation, which indicate on promising further investigations in this direction, were revealed. Key words: radionuclide therapy of malign

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25

Roy, Kamalika, and Susanta Lahiri. "Production and separation of Astatine Radionuclides: Some new addition to Astatine Chemistry." Applied Radiation and Isotopes 66, no. 5 (2008): 571–76. http://dx.doi.org/10.1016/j.apradiso.2007.12.005.

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26

Graton, Jérôme, Seyfeddine Rahali, Jean-Yves Le Questel, Gilles Montavon, Julien Pilmé, and Nicolas Galland. "Spin–orbit coupling as a probe to decipher halogen bonding." Physical Chemistry Chemical Physics 20, no. 47 (2018): 29616–24. http://dx.doi.org/10.1039/c8cp05690k.

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27

Bigourdan, Théo, Arnaud Cadiou, Arnaud Guertin, and Ferid Haddad. "Discussions on liquid bismuth target use as an alternative for astatine-211 production." EPJ Web of Conferences 285 (2023): 09002. http://dx.doi.org/10.1051/epjconf/202328509002.

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Astatine-211 is an alpha emitter that has been identified as a good candidate for targeted alpha therapy. There is an increasing demand on this radionuclide. Very intense beam from linac being put in operation nowadays could be used to meet this demand. This document presents the design exploration of concepts of liquid bismuth targets dedicated to astatine-211 production. Three concepts are presented and analyzed: a capsule, a fluid loop and a windowless fluid loop. Structural and thermal sizing were performed using mechanical Finite Element models (ANSYS Workbench) and Computational Fluid Dy

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28

Galland, N., G. Montavon, J. Y. Le Questel, and J. Graton. "Quantum calculations of At-mediated halogen bonds: on the influence of relativistic effects." New Journal of Chemistry 42, no. 13 (2018): 10510–17. http://dx.doi.org/10.1039/c8nj00484f.

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29

Rossi, Elisa, Matteo De Santis, Diego Sorbelli, Loriano Storchi, Leonardo Belpassi, and Paola Belanzoni. "Spin–orbit coupling is the key to unraveling intriguing features of the halogen bond involving astatine." Physical Chemistry Chemical Physics 22, no. 4 (2020): 1897–910. http://dx.doi.org/10.1039/c9cp06293a.

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30

Gouard, Sébastien, Catherine Maurel, Séverine Marionneau-Lambot, et al. "Targeted-Alpha-Therapy Combining Astatine-211 and anti-CD138 Antibody in a Preclinical Syngeneic Mouse Model of Multiple Myeloma Minimal Residual Disease." Cancers 12, no. 9 (2020): 2721. http://dx.doi.org/10.3390/cancers12092721.

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Despite therapeutic progress in recent years with the introduction of targeted therapies (daratumumab, elotuzumab), multiple myeloma remains an incurable cancer. The question is therefore to investigate the potential of targeted alpha therapy, combining an anti-CD138 antibody with astatine-211, to destroy the residual cells that cause relapses. A preclinical syngeneic mouse model, consisting of IV injection of 1 million of 5T33 cells in a KaLwRij C57/BL6 mouse, was treated 10 days later with an anti-mCD138 antibody, called 9E7.4, radiolabeled with astatine-211. Four activities of the 211At-9E7

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31

Hans-J. "Astata nigricans CAMERON, 1889 in Laos with description of the hitherto unknown female (Hymenoptera, Astatidae)." Linzer biologische Beiträge 54, no. 2 (2023): 517–21. https://doi.org/10.5281/zenodo.10414432.

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Hans-J (2023): Astata nigricans CAMERON, 1889 in Laos with description of the hitherto unknown female (Hymenoptera, Astatidae). Linzer biologische Beiträge 54 (2): 517-521, DOI: 10.5281/zenodo.10414432

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32

Кабанов, А. А., А. В. Зуев та А. А. Проценко. "Идентификация возмущений в электроприводах робототехнических систем на основе оптимального астатического наблюдателя". MORSKIE INTELLEKTUAL`NYE TEHNOLOGII)</msg> 4, № 4(66) (2024): 42–50. https://doi.org/10.37220/mit.2024.66.4.078.

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В статье рассматривается задача построения системы идентификации возмущающих воздействий в электроприводах робототехнических комплексов. Для её решения используется подход, основанный на использовании оптимальных астатических наблюдателей. Это позволяет избежать недостатков других методов идентификации, таких как необходимость высокочастотной коммутации скользящих наблюдателей. Оптимальные наблюдатели предлагается строить на основе редуцированных моделей исходной диагностируемой системы, получаемых с помощью специально разработанного алгоритма и имеющих меньшую размерность, по сравнению с исхо

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33

Zhou, Fengxiang, Yuan Liu, Zhaoxu Wang, et al. "A new type of halogen bond involving multivalent astatine: an ab initio study." Physical Chemistry Chemical Physics 21, no. 28 (2019): 15310–18. http://dx.doi.org/10.1039/c9cp02406a.

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34

Molina, B., J. R. Soto, and J. J. Castro. "Halogen-like properties of the Al13 cluster mimicking astatine." Physical Chemistry Chemical Physics 20, no. 17 (2018): 11549–53. http://dx.doi.org/10.1039/c8cp00494c.

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35

Toyoshima, Atsushi, and Atsushi Shinohara. "Nuclear Chemistry of Astatine (At)." RADIOISOTOPES 67, no. 10 (2018): 461–69. http://dx.doi.org/10.3769/radioisotopes.67.461.

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36

Vaidyanathan, Ganesan, and Michael Zalutsky. "Astatine Radiopharmaceuticals: Prospects and Problems." Current Radiopharmaceuticalse 1, no. 3 (2008): 177–96. http://dx.doi.org/10.2174/1874471010801030177.

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37

R. Zalutsky, Michael, and Marek Pruszynski. "Astatine-211: Production and Availability." Current Radiopharmaceuticalse 4, no. 3 (2011): 177–85. http://dx.doi.org/10.2174/1874471011104030177.

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38

Lindegren, Sture, Tom Bäck, Stig Palm, Holger Jensen, Per Albertsson, and Emma Aneheim. "Astatine-211: The Chemistry Infrastructure." Journal of Medical Imaging and Radiation Sciences 50, no. 4 (2019): S94. http://dx.doi.org/10.1016/j.jmir.2019.11.081.

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39

Lindegren, Sture, Tom Bäck, Stig Palm, Holger Jensen, Per Albertsson, and Emma Aneheim. "Astatine-211: The Chemistry Infrastructure." Journal of Medical Imaging and Radiation Sciences 50, no. 1 (2019): S24. http://dx.doi.org/10.1016/j.jmir.2019.03.076.

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40

Milesz, S., M. Jovchev, D. Schumann, V. A. Khalkin, and M. Milanov. "The EDTA complexes of astatine." Journal of Radioanalytical and Nuclear Chemistry Letters 127, no. 3 (1988): 193–98. http://dx.doi.org/10.1007/bf02164864.

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41

Liu, Lu, Seyfeddine Rahali, Rémi Maurice, et al. "An expanded halogen bonding scale using astatine." Chemical Science 12, no. 32 (2021): 10855–61. http://dx.doi.org/10.1039/d1sc02133h.

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Based on the halogen bonding between astatine monoiodide (AtI) and 16 Lewis bases, the newly established pKBAtI scale indicates that the halogen bond basicity of AtI follows the order C ≤ O ≤ S ≈ Se for the acceptor atomic site.

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42

Ostrowski, Sławomir, Agnieszka Majkowska-Pilip, Aleksander Bilewicz, and Jan Cz Dobrowolski. "On AunAt clusters as potential astatine carriers." RSC Advances 7, no. 57 (2017): 35854–57. http://dx.doi.org/10.1039/c7ra05224c.

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To understand interactions between astatine atoms with gold clusters the Au<sub>n</sub>At and Au<sub>n</sub>X clusters, n = 12 or 13, X = F, Cl, Br, and I, were calculated at the DFT level using basis sets with a quasi-relativistic pseudopotential.

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43

Thornton, Brett, and Shawn Burdette. "Three more unsung women – astatine discovery." Nature 567, no. 7748 (2019): 311. http://dx.doi.org/10.1038/d41586-019-00929-w.

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44

Ünak, Turan. "Some microdosmetric data on Astatine-211." Applied Radiation and Isotopes 58, no. 1 (2003): 115–17. http://dx.doi.org/10.1016/s0969-8043(02)00260-9.

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45

Sam Lemonick. "The puzzle and promise of astatine." C&EN Global Enterprise 98, no. 31 (2020): 22–24. http://dx.doi.org/10.1021/cen-09831-feature2.

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46

Hawkes, Stephen J. "Polonium and Astatine Are Not Semimetals." Journal of Chemical Education 87, no. 8 (2010): 783. http://dx.doi.org/10.1021/ed100308w.

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47

Takahashi, N., and H. Baba. "Anomalous solvent extraction behavior of astatine." Journal of Radioanalytical and Nuclear Chemistry 218, no. 1 (1997): 103–5. http://dx.doi.org/10.1007/bf02033983.

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48

Guminski, C. "The At-Hg (astatine-mercury) system." Journal of Phase Equilibria 16, no. 6 (1995): 525. http://dx.doi.org/10.1007/bf02646723.

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49

Dreyer, Rolf, Irene Dreyer, and Frank Rösch. "Zum Verhalten des Astatids in Halogenidlösungen." Zeitschrift für Chemie 22, no. 2 (2010): 54–56. http://dx.doi.org/10.1002/zfch.19820220215.

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50

Nishinaka, I., K. Hashimoto, and H. Suzuki. "Speciation of astatine reacted with oxidizing and reducing reagents by thin layer chromatography: formation of volatile astatine." Journal of Radioanalytical and Nuclear Chemistry 322, no. 3 (2019): 2003–9. http://dx.doi.org/10.1007/s10967-019-06900-3.

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