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1

Titova, V., D. Ivanov, Y. Aleksandrovich, I. Gorkovaya, and V. Rozhdestvenskiy. "Meaningful orientations and asthenia in pregnant women and young mothers during the first COVID-19 pandemic wave." European Psychiatry 65, S1 (2022): S489. http://dx.doi.org/10.1192/j.eurpsy.2022.1244.

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Introduction Pregnancy and childcare are naturally stressful for women, often accompanied by the asthenic syndrome. In a pandemic situation, this type of stress may be potentiated by external conditions. Objectives The study aimed to investigate the life-state orientations and asthenia levels of pregnant women and young mothers in the context of a pandemic. We also analyzed the correlations between the life-state orientations and the different types of asthenias. Methods Data collection was carried out in June 2020 using a Google form that we developed. Pregnant women and young mothers with ch
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2

Chutko, L. S., S. Yu Surushkina, E. A. Yakovenko, L. V. Scheglova, and L. M. Mirzaeva. "Cognitive impairment in asthenic disorders." S.S. Korsakov Journal of Neurology and Psychiatry 125, no. 3 (2025): 27. https://doi.org/10.17116/jnevro202512503127.

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The article presents a review of scientific publications devoted to cognitive aspects of asthenic disorders. The authors present different views on the etiology and basic mechanisms of pathogenesis of psychogenic asthenia and chronic fatigue syndrome, current diagnostic criteria for these diseases. The main attention is paid to the consideration of the neurocognitive deficit observed in mental asthenia and chronic fatigue syndrome. The role of cognitive control impairment in the development of adaptation disorders and the formation of asthenic conditions is considered. The results of studies o
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3

Успенский, Юрий Павлович, Юлия Александровна Фоминых, and Кямаля Низамитдиновна Наджафова. "The concept of asthenia in the clinic of internal diseases." University therapeutic journal, no. 2 (May 11, 2022): 52–63. http://dx.doi.org/10.56871/9760.2022.16.40.006.

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Астения является одной из наиболее распространенных неспецифических форм реагирования центральной нервной системы на самые разнообразные внешние и внутренние трудности. Согласно уровню обращаемости за медицинской помощью, более 60% жалоб пациентов приходится на долю связанных с астеническим синдромом, подобные расстройства наблюдаются у всех категорий населения. Проблеме астении посвящена данная лекция для врачей, в ней рассматриваются различные трактовки термина «астения», частота встречаемости астенических расстройств в клинике внутренних болезней, история формирования представлений об астен
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4

Magomedova, Kamila Sh, Yuriy V. Bykov, and Roman A. Bekker. "CHOLINE PREPARATIONS IN THE TREATMENT OF ASTHENIC STATES: MODERNITY AND PERSPECTIVES (A LITERATURE REVIEW WITH A CLINICAL CASE PRESENTATION)." Siberian Journal of Life Sciences and Agriculture 15, no. 2 (2023): 392–434. http://dx.doi.org/10.12731/2658-6649-2023-15-2-392-434.

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Purpose. To provide the reader with a detailed description of the biochemical and physiological effects of choline, which make it an indispensable component of our daily food. Then to thoroughly review all the relevant clinical data on the use of choline preparations for the treatment of asthenic and astheno-depressive conditions and cognitive impairments. Then, to present the reader with a clinical case from our own practice, illustrating the effectiveness of the use of choline alfoscerate as part of the combination therapy of a mild form of post-COVID astheno-depressive syndrome in a 19-year
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5

Bochkareva, V. A., M. M. Petrova, S. I. Zainidinova, Yu V. Lepilina, and N. Yu Shimokhina. "Prevalence and characteristics of asthenic syndrome in patients with chronic respiratory diseases living in Krasnoyarsk." Bulletin Physiology and Pathology of Respiration, no. 96 (June 24, 2025): 96–103. https://doi.org/10.36604/1998-5029-2025-96-96-103.

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Introduction. The coexistence of asthenia and chronic respiratory diseases substantially affects patients’ overall well-being, work capacity, treatment adherence and quality of life. Nevertheless, published data on the prevalenceof asthenia in chronic non-infectious lung diseases (CNLD) remain scarce. Aim. To assess the prevalence of asthenic syndrome among patients with CNLD living in Krasnoyarsk. Materials and methods. A clinic-based study was carried out in outpatient polyclinics in Krasnoyarsk from July to August 2023. We enrolled 381 patients diagnosed with chronic obstructive pulmonary d
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6

Mankovsky, D. S. "Hypoxic-ischemic brain injuries after cardiosurgical interventions: clinical options of somatogenic asthenic symptom complex in patients in the preoperative period." Reports of Vinnytsia National Medical University 25, no. 3 (2021): 404–8. http://dx.doi.org/10.31393/reports-vnmedical-2021-25(3)-09.

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Annotation. The article presents the results of studying the symptomatology of different clinical variants of somatogenous asthenic symptom complex (SASC). The primary material of the study was a specially developed thematic map, the completion of which involved the implementation of clinical and anamnestic study and taking into account about 30 symptoms. Clinical and statistical methods were used: anamnestic quantitative analysis, variation statistics, probabilistic distribution of clinical signs with assessment of the reliability of the obtained results. It was found that in the structure of
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7

Polushin, A. Yu, Ya B. Skiba, O. G. Smykova, et al. "Asthenia correction in a patient with acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation (case report)." Russian Medical Inquiry 7, no. 10 (2023): 693–99. http://dx.doi.org/10.32364/2587-6821-2023-7-10-13.

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Asthenic syndrome is one of the most common conditions in the clinical practice of medical specialists having various therapeutic spheres The genesis of asthenic disorder is diverse and can be represented by cerebrovascular pathology, metabolic disorders, hypoxia of various origin, as well as intoxication. Asthenic syndrome can be diagnosed in 70–75% of patients with oncological pathology at various treatment stages. The article presents a case study concerning the asthenic syndrome progression in a patient with acute lymphoblastic leukemia (ALL) and its successful correction by metabolic ther
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8

Nemkova, S. A. "Modern approaches to diagnosis and treatment of postinfectious asthenic syndrome in children." S.S. Korsakov Journal of Neurology and Psychiatry 125, no. 4 (2025): 42. https://doi.org/10.17116/jnevro202512504142.

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The article is devoted to an urgent problem — the diagnosis and treatment of Postinfectious asthenic syndrome in children and adolescents. The issues of etiology and pathogenesis, classification and clinical manifestations of postinfectious asthenia in children are considered in detail. Special attention is paid to the asthenic syndrome after acute respiratory viral infections and influenza, neuroinfections, and coronavirus infection. The high efficacy of the drug Mexidol in the prevention and comprehensive correction of postinfectious asthenic disorders, as well as concomitant autonomic, cogn
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9

Lokshina, Evelina E., Natalia A. Savitskaya, and Irina I. Khmelkova. "Asthenia in children: What's new for a pediatrician. A review." Pediatrics. Consilium Medicum, no. 3 (October 4, 2023): 122–26. http://dx.doi.org/10.26442/26586630.2023.3.202364.

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Pediatricians incidentally treat patients with asthenia (asthenic syndrome AS, asthenic condition). The etiology of this disorder is highly diverse. Asthenia is a universal response of the body to various distresses, leading to energy deficiency. The most common AS symptoms are weakness, fatigue, sleep disturbances, increased irritability, muscle pain, headache, etc. AS, including post-infectious AS, significantly worsens the quality of life of the child and his family, so it is necessary to report the manifestations promptly to make a differential diagnosis with other diseases with similar pr
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10

Шабров, Александр Владимирович, Юрий Павлович Успенский, Юлия Александровна Фоминых, and Кямаля Низамитдиновна Наджафова. "CLINICAL MANIFESTATIONS OF ASTHENIA." University therapeutic journal, no. 3 (November 24, 2022): 47–56. http://dx.doi.org/10.56871/8470.2022.34.17.006.

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Астения - одна из наиболее распространенных неспецифических форм реагирования центральной нервной системы на самые разнообразные внешние и внутренние трудности. Согласно уровню обращаемости за медицинской помощью, более 60% жалоб пациентов приходится на долю связанных с астеническим синдромом, подобные расстройства наблюдаются у всех категорий населения. В данной лекции, являющейся продолжением цикла клинических лекций, посвященных проблеме астении, рассматриваются общие клинические проявления, особенности течения различных клинических форм, а также структура астенического синдрома. Asthenia i
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11

Zozulya, S. A., B. A. Volel, A. V. Fomicheva, D. A. Andreev, I. N. Otman, and T. P. Klyushnik. "Clinical and Immunological Parameters in the Diagnostics of Asthenic Syndrome in Patients with Chronic Heart Failure." Psikhiatriya 20, no. 4 (2023): 96–106. http://dx.doi.org/10.30629/2618-6667-2022-20-4-96-106.

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Background: the significance of the asthenic syndrome as one of the most distressing symptoms affecting the clinical outcome of chronic heart failure (CHF), and insufficient understanding of the pathophysiological aspects of asthenia determines the need to study the clinical and biological features of this syndrome in cardiac pathology. Objective: to determine of a number of inflammatory and autoimmune blood parameters in patients with CHF associated with asthenic disorders in comparison with hypertensive disease in relation to clinical and gender-age characteristics of patients. Patients and
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12

Фоминых, Юлия Александровна, Андрей Михайлович Сарана, Кямаля Низамитдиновна Наджафова, and Наида Адалат кызы Иманвердиева. "ASTHENIA THERAPY IN THE CLINIC OF INTERNAL DISEASES." University therapeutic journal, no. 4 (November 24, 2022): 73–81. http://dx.doi.org/10.56871/4096.2022.75.19.008.

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Астения - одна из наиболее распространенных неспецифических форм реагирования центральной нервной системы на самые разнообразные внешние и внутренние трудности. Согласно уровню обращаемости за медицинской помощью, более 60 % жалоб пациентов приходится на долю связанных с астеническим синдромом. Подобные расстройства наблюдаются у всех категорий населения. Данная статья представлена вниманию читателей как заключительная, четвертая, из цикла клинических лекций, посвященных проблеме астении. Рассматриваются основные принципы лечения астенических расстройств, возможности психотерапии, физиотерапии
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13

Ebzeeva, E. Yu, O. D. Ostroumova, and E. V. Mironova. "Efficacy and safety of Mildronate in treatment of postinfectious asthenic syndrome (clinical examples)." Medical alphabet, no. 2 (June 12, 2020): 61–66. http://dx.doi.org/10.33667/2078-5631-2020-2-61-66.

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Asthenic syndrome is a non‑specific syndrome that is often found in general medical practice in patients with various somatic pathologies both during an exacerbation of a chronic disease, and after an acute process. The leading symptoms in the clinic of asthenia are pathological weakness and fatigue. According to various researchers, they are found in 15–45 % of people. To date, there is no universally accepted definition and clear classification of this syndrome. The main pathogenetic concepts are the psychosocial, infectious‑immune theory of asthenia. The development of asthenic syndrome in
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14

Mikhailov, A. O., S. A. Sokotun, N. G. Plekhova, et al. "Clinical manifestations of asthenic syndrome after coronavirus infection caused by SARS-CoV-2." Journal Infectology 15, no. 2 (2023): 60–67. http://dx.doi.org/10.22625/2072-6732-2023-15-2-60-67.

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Introduction. Asthenic disorders due to COVID-19 infection are generally classified under a recently introduced category in ICD-10: U09.9 Condition after COVID-19, unspecified. In this regard, it is necessary to study the clinical manifestations and systematize the asthenic syndrome after coronavirus infection in order to better understand the tactics of treatment and rehabilitation of this group of patients.Objective. To assess the prevalence of asthenic syndrome in patients who have had a coronavirus infection, to characterize and present its dynamics.Materials and methods. The study involve
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15

Bykov, Yuri V., and Roman A. Bekker. "On the specific treatment of asthenic states: focus on sulbutiamine." Terapevticheskii arkhiv 94, no. 5 (2022): 689–94. http://dx.doi.org/10.26442/00403660.2022.05.201533.

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In this article, we try to present the available data regarding the pharmacokinetics and pharmacodynamics of sulbutiamine (Enerion), the mechanisms of its anti-asthenic action. Then we analyze and summarize the available evidence base considering the efficacy and safety of Enerion for the treatment of asthenic syndromes. Then we compare Enerion with some other drugs. The results of our review indicate the high efficacy and safety of sulbutiamine in the treatment of asthenia. Our results also show that Enerion has some clinically relevant advantages over all alternatives we reviewed there.
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16

Zozulya, S. A., A. N. Simonov, and T. P. Klyushnik. "Logistic regression model for the prediction of asthenia development in schizophrenia based on inflammatory blood markers." European Psychiatry 67, S1 (2024): S280—S281. http://dx.doi.org/10.1192/j.eurpsy.2024.586.

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IntroductionAccording to a number of authors, inflammation is involved in the development of asthenic syndrome in different diseases. The results of our own studies indicate that the main feature of the spectrum of inflammatory markers in patients with asthenic syndrome in schizophrenia is low enzymatic activity of leukocyte elastase against the background of high levels of other inflammatory markers. Presumably, the decrease in LE activity may be associated with functional exhaustion of neutrophils and/or their transmigration to the brain through the disrupted blood-brain barrier due to a lon
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17

Kamchatnov, P. R., E. Yu Solov’eva, D. R. Khasanova, and V. V. Fateeva. "Asthenic and cognitive disorders after the COVID-19 infection." Russian Medical Inquiry 5, no. 10 (2021): 636–41. http://dx.doi.org/10.32364/2587-6821-2021-5-10-636-641.

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Asthenic disorders are one of the most critical and challenging issues in various medical disciplines. Postinfectious asthenia is relatively common. Its major presentations are a significant long-lasting physical and intellectual fatigue. The COVID-19 infection results in numerous emotional, cognitive, and vegetative disorders, drastically reducing the quality of life and preventing rehabilitation and returning to baseline everyday activity. The rationale for introducing the term "post-COVID syndrome" is accounted for by the high prevalence of asthenic, cognitive, and vegetative disorders afte
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18

Kutlubaev, Mansur A., and Albina I. Akhmetova. "Poststroke Asthenic Disorder." Annals of Clinical and Experimental Neurology 17, no. 4 (2024): 64–71. http://dx.doi.org/10.54101/acen.2023.4.8.

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Asthenic disorders are seen in approximately half of poststroke patients. The mechanisms underlying poststroke asthenia (PSA) are related to brain connectome damage, as well as neuroinflammatory and neuroendocrine mechanisms. PSA is associated with a lack of energy, lassitude, and fatigue that do not improve after rest or sleep; it is differentiated from depression, apathy, and daytime drowsiness. Risk factors for PSA include female gender, anxiety and depressive disorders, severe neurological deficit, sleep disorders, diabetes etc. Treatment of PSA includes cognitive behavioral therapy graded
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19

Weinberg, M. "Psychoses after typhus. Vinokurova, Prof. Gilyarovsky (Journal of Psychol., Neurol. and Psychiatry, 1922, I)." Kazan medical journal 19, no. 1 (2021): 105. http://dx.doi.org/10.17816/kazmj78733.

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Typhus brings a number of severe changes to the mental sphere of patients, which are characterized as asthenic-depressive states of emotional weakness, and clinically can be united into one group under the name of post-infectious asthenia.
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20

Pavlov, Aleksandr I., Aleksandr F. Ivolgin, Sergei V. Katenko, et al. "Diagnostics and treatment of non-alcoholic fatty liver disease with concomitant asthenic syndrome." Terapevticheskii arkhiv 93, no. 8 (2021): 890–96. http://dx.doi.org/10.26442/00403660.2021.08.200974.

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Aim. Analysis of the effectiveness of therapy for non-alcoholic fatty liver disease (NAFLD) with severe asthenic syndrome.
 Materials and methods. In the period from 2017 to 2019, on the basis of the gastroenterology center of the Vishnevsky 3-rd Central Military Clinical Hospital, 247 patients with NAFLD, including those at the stage of steatohepatitis, and severe asthenic syndrome were examined and treated. The main group included 124 patients, the control group 123 patients. All patients underwent complex laboratory and instrumental diagnostics and neuropsychological research using the
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21

Malyavin, A. G., A. V. Gorelov, E. E. Vasenina, et al. "Post-infectious asthenia." Infekcionnye bolezni 22, no. 1 (2024): 124–36. http://dx.doi.org/10.20953/1729-9225-2024-1-124-136.

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The meeting of the Expert Council of the Russian Scientific Medical Society of Therapists and the Academician V.I.Pokrovsky National Association of Infectious Disease Specialists, devoted to the problem of postinfection asthenia was held on 11.07.2023 in Moscow. Post-infectious asthenia is a fairly common symptom complex, the main manifestations of which are pronounced prolonged physical and intellectual fatigue, a feeling of fatigue after infectious diseases caused by viral, bacterial and other pathogens. Asthenic syndrome is manifested by increased fatigue, weakness, sleep disturbance, loss
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22

Levchenko, E. V., and V. S. Kuzminov. "Age and gender characteristics of the prevalence of asthenic syndrome." Clinical Medicine (Russian Journal) 102, no. 9-10 (2025): 750–53. https://doi.org/10.30629/0023-2149-2024-102-9-10-750-753.

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The significance of the studied problem is determined by the high prevalence of asthenic syndrome, which accompanies numerous somatic and psychosomatic pathologies. It is believed that asthenia is more common among the female population, but this is apparently related to physiological processes occurring in a woman’s body.Objective of the study: to examine the prevalence of asthenic syndrome among men and women according to age.Material and methods. The study involved 387 respondents who were required to fill out a questionnaire based on the “Subjective Assessment Scale for Asthenia (MFI20).”
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23

Шабров, Александр Владимирович, Юлия Александровна Фоминых, Юрий Павлович Успенский, and Кямаля Низамитдиновна Наджафова. "PRINCIPLES OF ASTHENIA DIAGNOSIS." University therapeutic journal, no. 3 (November 24, 2022): 57–63. http://dx.doi.org/10.56871/3052.2022.73.10.007.

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Астения - одна из наиболее распространенных неспецифических форм реагирования центральной нервной системы на самые разнообразные внешние и внутренние трудности. Согласно уровню обращаемости за медицинской помощью, более 60 % жалоб пациентов приходится на долю связанных с астеническим синдромом. Подобные расстройства наблюдаются у всех категорий населения. В данной лекции, которая является продолжением цикла клинических лекций, посвященных проблеме астении, рассматриваются основные принципы диагностики астенических расстройств, также приведены опросники, используемые в психодиагностике данных с
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24

Shulpekova, Julia O., E. N. Shirokova, V. Yu Rusyaev, and I. V. Damulin. "NEUROLOGICAL MANIFESTATIONS OF PRIMARY CHOLESTATIC LIVER DISEASES." Medical Journal of the Russian Federation 24, no. 4 (2018): 213–19. http://dx.doi.org/10.18821/0869-2106-2018-24-4-213-219.

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The most typical and early signs of primary cholestatic liver diseases are represented by itching, prominent asthenia and autonomic dysfunction. These abnormalities significantly affect the quality of life. The data obtained relate itching and asthenic syndrome in cholestatic liver diseases to pathological changes of the central nervous system (CNS). The special scales for assessment of severity of asthenic manifestations, itching and quality of life in primary biliary cholangitis were developed. Besides, memory defects and loss of concentration ability are quite often seen even in non-cirrhot
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25

Bekuzarova, Madina R., and Amirkhan A. Kumakhov. "Clinical and laboratory evaluation of the effectiveness of the nootropic drug Actitropil (fonturacetam) in the treatment of asthenic syndrome." Consilium Medicum 25, no. 11 (2024): 728–35. http://dx.doi.org/10.26442/20751753.2023.11.202576.

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Background. Asthenia is one of the most common symptoms in the clinical practice of a doctor of any specialty. This is due to the high incidence of this pathology: in patients with chronic somatic diseases from 45% to 90%, with an acute pathological process – about 55%. There are no uniform standards for the treatment of asthenic disorder; however, the basis for the medical correction of this pathology is nootropic drugs.
 Aim. To study the clinical efficacy and safety of the nootropic drug Actitropil (fonturacetam) in patients with various types of asthenic disorder.
 Materials and
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26

Kopylov, F. Yu, Yu M. Nikitina, E. A. Makukh, and A. L. Syrkin. "Study of the efficiency and safety of Ladasten therapy in patients with cardiovascular disease." CardioSomatics 1, no. 1 (2010): 57–61. http://dx.doi.org/10.26442/cs44966.

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A trial was carried out to study the efficiency and safety of therapy with the new antiasthenic drug Ladasten. The findings suggest its high safety and efficiency and good tolerability of Ladasten in the treatment of asthenia and asthenic spectrum disorders, the development of which is associated with cardiovascular disease.
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27

Kulagina, Anastasiya P., and Aleksei A. Suzdaltsev. "Asthenic syndrome in the convalescents of ixodid tick-borne borrelioses." Aspirantskiy Vestnik Povolzhiya 23, no. 1 (2023): 10–14. http://dx.doi.org/10.55531/2072-2354.2023.23.1.10-14.

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Aim to study the catamnesis of patients with ixodid tick-borne borreliosis in the period of convalescence who presented the signs of asthenic syndrome.
 Material and methods. The study was based on the data of prospective dispensary observation of 37 in-patients diagnosed with "ixodid tick-borne borreliosis, erythemic form, moderate severity, acute course" who received treatment at the Clinic of Infectious Diseases of the SamSMU in 2016-2019. The subjects were divided into 3 groups according to their age: the first age-group from 18 to 35 years included 12 people, the second group ranged
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28

Vinogradov, E. I., N. V. Selyanina, V. G. Zlotnikova, and O. N. Sumlivaya. "Sanatorium Rehabilitation of post-COVID Asthenic Syndrome in School-Age Children." Doctor.Ru 23, no. 6 (2024): 46–51. http://dx.doi.org/10.31550/1727-2378-2024-23-6-46-51.

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Aim. To study the effects of sanatory rehabilitation factors for the intensity of asthenic manifestations of post-COVID syndrome in school-aged children. Design. A non-randomized controlled study was conducted. Materials and methods. We examined 60 children aged 8 to 13 years old with asthenic manifestations of post-COVID syndrome; 20 healthy children were used as controls. Rehabilitation was organised at Svetlana health camp (a branch of the Territorial Clinical Hospital, Perm). All children shared their complaints and medical history as well as had their somatic and neurological status check
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29

Lokshina, A. B., and V. V. Zakharov. "The duality of asthenia and cognitive impairments in cerebral diseases." Meditsinskiy sovet = Medical Council, no. 21 (November 22, 2023): 20–27. http://dx.doi.org/10.21518/ms2023-401.

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Asthenia is a pathological condition characterized by abnormal, spontaneous fatigue that occurs without exercise, continues for a long time and does not go away after rest. With asthenia, performance decreases, and difficulties arise in maintaining prolonged mental and physical stress. The presence of these disorders is associated with a decrease in quality of life, an increase in morbidity and mortality in general. In general, we can say that complaints of weakness, tiredness and fatigue are the most common when visiting a primary care doctor. The article presents various clinical manifestati
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30

Pugliese, Bruno Davide, Giovanna Garuti, Lucia Bergamini, et al. "Masticatory Functionality in Post-Acute-COVID-Syndrome (PACS) Patients with and without Sarcopenia." Oral 3, no. 1 (2023): 77–91. http://dx.doi.org/10.3390/oral3010008.

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Musculoskeletal symptoms are common in both acute COVID-19 disease and post-acute sequelae (Post-Acute COVID Syndrome). The purpose of this study is to investigate whether there are reduced levels of masticatory function in patients with PACS (Post Acute COVID Syndrome) who suffer from sarcopenia, under the hypothesis that the latter may also involve the masticatory muscles. This study includes 23 patients hospitalized for COVID-19 between February 2020 and April 2021 and currently suffering from PACS. Among these PACS patients, 13/23 (56%) suffer from sarcopenia, 5/23 (22%) complain of asthen
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31

Moroz, Denis I., Anna S. Isaeva, Inna A. Lavrinenko, and Dmitry V. Semin. "Complex therapy of asthenia and cognitive decline against the background of COVID-19 infection in real clinical practice." Clinical review for general practice 3, no. 5 (2022): 47–50. http://dx.doi.org/10.47407/kr2022.3.5.00161.

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Asthenia syndrome is an actual problem during the pandemic of a new coronavirus infection (COVID-19) due to the high frequency of occurrence, regardless of the severity of the disease, this condition can develop in all patients who have had COVID-19. The clinical picture of postcovid syndrome is very diverse, but the most common are asthenic disorders, anxiety-depressive disorders and cognitive disorders
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32

Adamchuk, Nataliia M., and Olena Y. Sorokina. "ANALYSIS OF PSYCHO-EMOTIONAL STATE AND THE SEVERITY OF ASTHENIC SYNDROME IN CHILDREN WITH ACUTE LEUKEMIA AFTER THE FIRST STAGE OF CHEMOTHERAPY." Wiadomości Lekarskie 72, no. 8 (2019): 1460–62. http://dx.doi.org/10.36740/wlek201908107.

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Introduction: Children and adolescents with hematological diseases are constantly in a state of prolonged psychological stress caused by hospitalization, debilitating treatment, lifestyle changes, which ultimately leads to a significant reduction in the quality of life. In this connection it is necessary to study the dynamics of mental and emotional condition of the child at different stages of chemotherapy and the timing of formation of asthenic syndrome. The aim: Determine the presence of psycho-emotional disorders and the severity of asthenic syndrome in children with acute leukemia after t
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33

Zolotovskaia, I. A., P. R. Shatskaia, I. L. Davydkin, and O. A. Shavlovskaya. "Postcovid-19 Asthenic Syndrome." Neuroscience and Behavioral Physiology 52, no. 2 (2022): 191–95. http://dx.doi.org/10.1007/s11055-022-01222-6.

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34

Khaibullina, D. Kh, and Y. N. Maksimov. "Asthenic post-COVID syndrome." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 123, no. 3 (2023): 61. http://dx.doi.org/10.17116/jnevro202312303161.

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35

Krot, A. F., and I. N. Lastovka. "PSYCHOLOGICAL ADAPTATION FEATURES IN PEDIATRICIANS." Health and Ecology Issues, no. 1 (March 28, 2015): 92–96. http://dx.doi.org/10.51523/2708-6011.2015-12-1-19.

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Objective: to detect asthenia, weariness and sleep disorders in pediatricians. Material and methods. Cross-sectional study of 44 pediatricians with the use of a package of psychometric tools (scale for assessing weariness SB-2003, Pittsburgh Insomnia Rating Scale (PIRS), subjective rating scale of asthenia MFI-20). Results. 42 (95 %) of the respondents from the study group revealed moderate or severe emotional weariness. Only 5 (11 %) of the respondents did not reveal any signs of asthenic symptomatic complex. All the respondents in the survey had this or that form of a sleep disorder. Conclus
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Kamchatnov, P. R., O. A. Kislyak, L. A. Skipetrova, R. A. Cheremin, and V. V. Fateeva. "Treatment of asthenic syndrome in outpatient practice: meta-analysis of the results concerning clinical trials of an antiasthenic drug." RMJ, no. 11 (2024): 19–25. https://doi.org/10.32364/2225-2282-2024-11-4.

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The article provides a comprehensive overview of scientific publications addressing asthenic syndrome (AS). It analyzes study results related to AS in a wide range of somatic and neurological conditions, across patients of various age groups. The article discusses differing perspectives on the primary mechanisms underlying the pathogenesis of AS and examines the patterns of its clinical manifestations in middle-aged and elderly populations. Key therapeutic approaches for managing AS are outlined. Particular emphasis is placed on the results of clinical studies investigating the efficacy of the
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Steinfeld, Torill. "Sisters in the asthenia. On John Browns theory of excitability, Brunonianism, and asthenic women." Edda 91, no. 04 (2005): 286–301. http://dx.doi.org/10.18261/issn1500-1989-2004-04-03.

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Putilina, M. V. "Asthenic disorders: contradictions and paradigms." Meditsinskiy sovet = Medical Council, no. 3 (May 2, 2024): 89–96. http://dx.doi.org/10.21518/ms2024-122.

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Asthenic disorders are a pressing problem for modern medicine. The lack of specificity of this disease makes it difficult to make a nosological diagnosis, since these disorders occur not only in somatic pathologies and infections, but also in various neurological and mental diseases. Attempts at systematization taking into account clinical variability did not lead to a single paradigm, since they did not reflect all possible variants of disorders. In ICD-10, conditions, the main manifestation of which is asthenia, are considered under various headings: Neurasthenia – F48.0; Organic emotionally
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Svyrydova, N., T. Parnikosa, V. Sereda, I. Kucheieva, and N. Ingula. "Features of treatment of asthenic-neurotic syndrome and sleep disorders in patients with chronic cerebrovascular accident." East European Journal of Neurology, no. 2(8) (June 20, 2016): 52–58. http://dx.doi.org/10.33444/2411-5797.2016.2(8).52-58.

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Asthenic syndrome can be regarded as pathologically modified version of the adaptation of the nervous system in response to physical and mental strain, exogenous or endogenous intoxication, vascular disorders. Of particular importance in recent years given asthenic syndrome and limits of neuroses, the need for complex drug therapy in the treatment of asthenic-neurotic states. In view of the fact that the leading element of the pathogenesis of asthenic syndrome are disorders of the central nervous system, the main tool of pharmacological correction in this situation should be considered a compr
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Marushchak, A. A., T. F. Popova, I. A. Gribacheva, and E. V. Petrova. "Impact of coronavirus infection on asthenic syndrome in patients with ischemic stroke." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 9 (September 20, 2022): 652–58. http://dx.doi.org/10.33920/med-01-2209-02.

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It is known that the presence of asthenic syndrome is characteristic of ischemic brain damage. At the same time, patients with acute cerebral ischemic stroke, who have been diagnosed with a laboratory-confirmed coronavirus infection with a mild and asymptomatic course without signs of damage to other organs, are of particular interest. The aim of the research was to identify and study the severity and duration of asthenic syndrome in patients with ischemic stroke under conditions of the coronavirus infection in order to determine the effect of asthenia on the quality of life in the post-COVID
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Nesina, Irina A., Alexander V. Shakula, Alexander I. Pavlov, et al. "PANTOGEMATOGEN-C: A COMPLEX APPROACH TO ASTHENIC SYNDROME IN MILITARY SERVANTS." Bulletin of Medical Science 33, no. 1 (2024): 62–69. http://dx.doi.org/10.31684/25418475-2024-1-62.

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Introduction. The utilization of the dietary supplement "Pantohematogen-C" within the medical and psychological rehabilitation program for military personnel with secondary asthenic syndrome in a sanatorium-resort setting has demonstrated its positive impact on normalizing key asthenia symptoms, including physical and mental exhaustion, vegetative disorders, and sleep disturbances. Aim. This study aimed to enhance the effectiveness of comprehensive medical and psychological sanatorium-resort rehabilitation for military personnel with asthenic syndrome using the dietary supplement "Pantohematog
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Kamchatnov, P. R., O. Yu Tsarapkina, N. G. Malyukova, et al. "Treatment of post-traumatic cognitive disorders and asthenia: results of an observational study." Neurology, Neuropsychiatry, Psychosomatics 16, no. 4 (2024): 14–20. http://dx.doi.org/10.14412/2074-2711-2024-4-14-20.

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Post-traumatic cognitive impairment (CI) and asthenia are common, disabling and often obligatory manifestations of traumatic brain injury (TBI). The search for effective drugs against CI and asthenia after TBI is of great importance. Objective: to investigate the efficacy and safety of Prospekta in the treatment of post-traumatic CI and asthenia in real-life clinical practice. Material and methods. The observational study involved 50 patients of both sexes aged 21–45 years (mean age 41.5 ± 5.9 years) with complaints of CI and fatigue after TBI received within the last 2 years, who were prescri
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Simonov, A. N., T. P. Klyushnik, and S. A. Zozulya. "Evidence-Based Psychiatry: Paraclinical Diagnostics of Asthenic Syndrome in Schizophrenia Based on the Determination of Leukocyte-Inhibitory Index." Psychiatry 18, no. 2 (2020): 6–12. http://dx.doi.org/10.30629/2618-6667-2020-18-2-6-12.

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A leukocyte-inhibitory index (LII) is the ratio of the proteolytic enzyme leukocyte elastase (LE) to its inhibitor, an α1- proteinase inhibitor (α1-PI). LII characterizes the activity of the proteolytic system and can be considered as a potential objective criterion that determines both the course and the outcome of the disease. The changes of LII in schizophrenia patients with clinically diagnosed asthenia (schizoasthenia) and patients with schizophrenia without clinical signs of this syndrome were revealed. The objective: to study the possibility of the 95% confidence intervals for a compara
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Zolotovskaia, I. A., P. R. Shatskaia, I. L. Davydkin, and O. A. Shavlovskaya. "Post-COVID-19 asthenic syndrome." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 121, no. 4 (2021): 25. http://dx.doi.org/10.17116/jnevro202112104125.

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Zhukova, I. A., E. S. Kolupaeva, and N. G. Zhukova. "Parkinson disease and asthenic syndrome." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 118, no. 11 (2018): 60. http://dx.doi.org/10.17116/jnevro201811811160.

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Chutko, L. S., and S. Yu Surushkina. "Asthenic disorders. History and modernity." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 120, no. 6 (2020): 131. http://dx.doi.org/10.17116/jnevro2020120061131.

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Sabovchyk, A. Ya, M. M. Oros, and N. O. Savytska. "Asthenic syndrome in brain disorders." INTERNATIONAL NEUROLOGICAL JOURNAL 16, no. 2 (2020): 76–79. http://dx.doi.org/10.22141/2224-0713.16.2.2020.200967.

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48

Shavlovskaya, O. A., and I. A. Bokova. "Asthenic disorders correction with Recognan." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 124, no. 3 (2024): 57. http://dx.doi.org/10.17116/jnevro202412403157.

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49

Malkova, A. A., A. A. Medvedeva, and Yu K. Shadrina. "Prevalence of asthenia among fourth-year medical students and its pathophysiological aspects." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 6 (May 28, 2025): 784–96. https://doi.org/10.33920/med-01-2506-08.

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Asthenic syndrome is a common pathological condition characterized by structural and symptomatic polymorphism. The issue is particularly relevant among medical students who experience intense academic loads. This study assessed the prevalence and severity of asthenia in 296 fourth-year medical students by means of a standardized scale. The results showed that 45.6 % of the respondents had no signs of asthenia, 45.95 % had a mild degree, and 8.45 % had a moderate degree. Statistically significant gender differences were identified: asthenia was more prevalent among female students (58.26 % vs.
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Vinogradov, Eugene I. "Clinical and laboratory phenotype of postcovid asthenic syndrome in children of primary school age." Perm Medical Journal 40, no. 1 (2023): 34–40. http://dx.doi.org/10.17816/pmj40134-40.

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Objective. To determine the clinical and laboratory features of the postcovid syndrome in children of primary school age.
 Materials and methods. The analysis of complaints and anamnesis, somatic and neurological status in 24 children who had a new coronavirus infection was carried out; the results were also analyzed according to the Subjective Asthenia Scale (version for parents), the Quality of Life Assessment Scale (version for children), the Waynes questionnaire and scheme, the functional status scale. The concentration of monocytic chemotactic factor in the saliva was determined usin
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