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Dissertations / Theses on the topic 'Asthma model'

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Published: 25 January 2025

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1

Williams, Julie M. "Coping with asthma : investigation and intervention using the self-regulation model." Thesis, University of St Andrews, 1995. http://hdl.handle.net/10023/2800.

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The Self-Regulation Model (Leventhal, Nerenz & Steele, 1984) highlights the roles of patients' illness representations, coping, emotional reactions and appraisal of coping in the progression of chronic disease. This thesis incorporates previous literature on adherence, panic-fear and selfmanagement interventions into the model in order to (a) investigate coping with asthma and (b) develop an intervention aimed at improving asthmatic control. New measures of asthmatic control and illness representations of the consequences of having asthma were developed in order to operationalise the model
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2

Ollé, Monge Marta. "Novel insights in occupational asthma due to persulfate salts." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399518.

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El asma relacionada con el trabajo se define como el asma causada por la exposición a agentes que se encuentran en el lugar de trabajo, y es responsable de hasta un 25% de los casos de asma de inicio en la edad adulta. En los países industrializados es una de las causas más comunes de enfermedad respiratoria ocupacional. Concretamente, el asma ocupacional (AO) se atribuye a exposiciones en un particular ambiente ocupacional y no a estímulos fuera del lugar de trabajo, y puede estar inducido tanto por la sensibilización a un agente específico (AO inmunológico) como por exposición a sustancias i
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3

Gould, David James. "Leucocyte recruitment in a model of allergic airways disease." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384947.

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4

Varley, John Graeme. "Development of a model of allergic airways disease A." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385226.

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5

Zhang, Youming. "A genome-wide search for asthma-associated quantitative traits loci in a mouse model of allergic asthma." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312554.

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6

Huggins, Mary L. "A parasite model for lung eosinophilia." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240928.

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7

Finlay, Alison. "Kinetics of pulmonary eosinophilia in a mouse model." Thesis, University of York, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245971.

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8

Stoten, Adam. "A model for non-atopic eosinophilic inflammation in the athymic rat." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368238.

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9

Seminario, Maria Cristina. "Development of a novel guinea pig model of allergic airways disease." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239410.

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10

Lee-Fowler, Tekla. "Determination of allergen sensitization and comparison of subcutaneous and mucosal (intranasal) allergen-specific immunotherapy in an experimental model of feline asthma." Diss., Columbia, Mo. : University of Missouri-Columbia, 2009. http://hdl.handle.net/10355/6723.

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Thesis (M.S.)--University of Missouri-Columbia, 2009.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. "May 2009" Includes bibliographical references.
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11

Schulz, Nikola. "microRNA profiling and target identification in a mouse model for allergic asthma." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-143012.

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12

John, Elinor. "Lung function responses and mucus secretion in a model of chronic asthma." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/54093/.

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In summary, these observations demonstrate that lung function appears to be impaired by mucus secretion in an experimental animal model of chronic allergic asthma. The guinea pig model of chronic asthma may be utilised to investigate the development of a mucus hypersecretory phenotype in asthma or identify potential targets for the development of novel therapies aimed at reducing goblet cell mucus production or secretion.
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13

Kintner, Eileen Kae 1957. "Testing of the school-aged child and adolescent acceptance of asthma model." Diss., The University of Arizona, 1996. http://hdl.handle.net/10150/282275.

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School-aged children and adolescents experiencing a chronic illness have verbalized and demonstrated difficulty in accepting their illness and the need for continued treatment. Few researchers have explored the school-aged child/adolescent process of acceptance. To assist school-aged children/adolescents toward acceptance, nurses must have a clear understanding of the process. This study is part of an ongoing program of research designed to increase nurses' understanding of the process of coming to accept asthma. The purpose of this study was to explore relationships among variables in the Sch
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14

El-Hashim, Ahmed Zakaria. "Characterisation of acute and chronic airway hyperresponsiveness in an allergic rabbit model." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286197.

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15

Schooley, Elizabeth K. "The effects of an antiseritonergic drug and antihistamine in an experimental model of feline asthma." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/5033.

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Thesis (M.S.)--University of Missouri-Columbia, 2007.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Vita. "May 2007" Includes bibliographical references.
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16

Lundquist, Gabriel, and Samuel Holmström. "Digital Treatment of Asthma Patients in Swedish Primary Care : A Business Model Study." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-279628.

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The cost of healthcare has been steadily increasing over the last decades and is becoming an increasing liability on the public finances. Much of these resources are directed to the primary care, and more specifically to the treatment of chronic diseases within the primary care. Digital healthcare, which has been highlighted as a potential way of increasing the efficiency within the primary care, has so far been unable to provide continuous care to patients with chronic diseases. New digital business models are needed to properly treat these patient groups. This study has evaluated the feasibi
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17

Clark, Brenda Rose. "Development of an Air Pollution Asthma Risk-Screening Model for Ohio Elementary Schools." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1345233071.

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18

Allakhverdieva, Zoulfia. "Modulation of airway responses to antigen in a rat model of allergic asthma." [Montréal] : Université de Montréal, 2002. http://wwwlib.umi.com/cr/umontreal/fullcit?pNQ73468.

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Thèse (Ph. D.)--Université de Montréal, 2002.<br>"NQ-73468." "Thèse présentée à la faculté des études supérieures en vue de l'obtention du grade de philosophiae doctor (Ph. D.) en sciences biomédicales." Version électronique également disponible sur Internet.
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19

Finney, Paul Anthony. "Development and characterisation of an in vivo model of β₂-adrenoceptor desensitisation in the rat". Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/7671.

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20

Hutson, Penelope Ann. "Investigations into the mechanisms of late phase responses in guinea pig airways." Thesis, University of Southampton, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328461.

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21

Lynch, Brittany. "Investigating the therapeutic potential of polyclonal antibodies in a murine model of allergic asthma." Thesis, Lynch, Brittany (2012) Investigating the therapeutic potential of polyclonal antibodies in a murine model of allergic asthma. Honours thesis, Murdoch University, 2012. https://researchrepository.murdoch.edu.au/id/eprint/41661/.

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Using the OVA mouse model of allergic airway disease, a histological grading system was established to evaluate four cardinal features of allergic asthma: Perivascular Inflammatory Cuffing, Peribronchial Inflammatory Cuffing, Goblet Cell Hyperplasia, and Tissue Eosinophilia. Using histochemical methods, this grading system was applied to identify a shallow dose response between allergen dose and resultant histopathology. This trend reached maximal effect with low doses of allergen and was observed in both perivascular and peribronchial cuffing thickness. A degree of goblet cell hyperplasia was
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22

Ghosh, Sumit. "Immunomodulatory Role of B Lymphocytes and Hyaluronic Acid in a Murine Model of Allergic Asthma." Diss., North Dakota State University, 2012. https://hdl.handle.net/10365/26663.

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In the world today, asthma affects more than 235 million people. The widespread prescription of inhaled corticosteroids?the current gold standard of asthma control medication?allows many asthmatics to live symptom-free and has significantly reduced the number of deaths due to asthma. However, when the disease is poorly controlled, for example due to ubiquitous exposure to airborne fungal conidia, this chronic inflammatory disease often results in lung dysfunction caused by airway architectural changes. The role of B lymphocytes in allergic asthma has been relegated to the production of IgE wit
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23

Oberholzer, Nanette. "Evaluation of the anti-inflammatory properties of a complex homeopathic product Modul8® using the BALB/c murine asthmatic animal model /." Access to E-Thesis, 2009. http://upetd.up.ac.za/thesis/available/etd-04292010-092056/.

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24

Evaldsson, Chamilly. "Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects." Doctoral thesis, Linköpings universitet, Klinisk kemi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-19122.

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In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. However, these drugs have potent and diverse effects and often act by inhibiting events subsequent to initiation of the inflammatory response, leading to more or less severe side-effects, especially when used in high doses for long periods of time. For this reason, strategies aimed at early inhibition of recruitment an
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25

Wong, Pei Se. "Development of a pharmaceutical care model for the long-term management of asthma in Malaysia." Thesis, University of Strathclyde, 2012. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=16855.

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Asthma is one of the most common chronic diseases affecting adults and children in the world. To date, it is estimated to affect over 300 million of the world population and presents a significant healthcare burden in all countries. In the United State (US) and Europe, asthma control is reported to be achievable by only 5% of asthmatics. Asthma is also one of the top 5 conditions, which impact on healthcare expenditures in the US. Asthma affects 4.6% of the population in Malaysia and has major effects on morbidity, mortality and healthcare costs. The development of a pharmaceutical care model
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26

Jessop, Donna Catherine. "The Self-Regulatory Model and its application to asthma and adherence to inhaled preventative medication." Thesis, University of Kent, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297343.

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27

Hafezi, Nazila. "An integrated software package for model-based neuro-fuzzy classification of small airway dysfunction." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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28

Spong, Amanda J. "Are children's thoughts and feelings about illness related to medication use and symptom control? : an examination of the self regulatory model." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327135.

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29

Lulham, George W. "The effect of cytokine administration on treatment and prevention of asthma in a sensitized mouse model." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0008/NQ52173.pdf.

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30

Lam, Diane Phuong Nghinh. "Characterization of the immunomodulatory activities of sterile house dust extracts in a murine model of asthma." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p1447798.

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Thesis (M.S.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed Feb. 5, 2008). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 60-66).
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31

Strangman, Wendy K. "Anti-inflammatory capabilities of compounds from marine bacteria in a mouse model of allergic inflammation and asthma." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3284210.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed March 14, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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32

Schulz, Nicola [Verfasser], and Elisabeth [Akademischer Betreuer] Weiß. "microRNA profiling and target identification in a mouse model for allergic asthma / Nikola Schulz. Betreuer: Elisabeth Weiß." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1022523953/34.

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33

Alrifai, Mohammed [Verfasser], and Holger [Akademischer Betreuer] Garn. "Resolution of airway remodelling in a mouse model of chronic allergic asthma / Mohammed Alrifai ; Betreuer: Holger Garn." Marburg : Philipps-Universität Marburg, 2019. http://d-nb.info/1183909020/34.

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34

Musaad, Salma MA. "Anthropometric Measures of Obesity and the Association with Asthma and Other Allergic Disorders: Cincinnati Children’s Allergy and Immunology Clinic Cohort." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1192570691.

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35

Steffan, Breanne. "Interactions of Aspergillus fumigatus and Pseudomonas aeruginosa Contribute to Respiratory Disease Severity and Death." North Dakota State University, 2019. https://hdl.handle.net/10365/31346.

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The lung was recently identified to consist of a complex microenvironment made up of microorganisms that interact with one another and the host cells via direct and indirect interactions. As a result, understanding the dynamic of the microbiome in chronic respiratory diseases has become the focus of pulmonary researches. In cystic fibrosis (CF), chronic infections are a comorbidity associated with the genetic disorder. Recently, it was noted that the interactions of the fungus, Aspergillus fumigatus, and the bacterium, Pseudomonas aeruginosa together contribute to more severe disease outcomes
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36

Molter, Anna. "Air pollution exposure and respiratory health in childhood." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/air-pollution-exposure-and-respiratory-health-in-childhood(86388151-13d1-499d-be59-89d6d87e036f).html.

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Asthma is the most common chronic disease in children and the effects of air pollution exposure on asthma and respiratory health in children have been a growing concern over recent decades. Although a number of epidemiological studies have been carried out in this field, these have produced conflicting results. The aim of this study was to assess the effects of long term exposure to nitrogen dioxide (NO2) and particulate matter (PM10) on asthma prevalence and lung function in children. To achieve this, a novel exposure model was developed and evaluated, which allowed retrospective exposure ass
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37

Tamulis, Tomas. "Association between area socioeconomic status and hospital admissions for childhood and adult asthma." [Tampa, Fla.] : University of South Florida, 2005. http://purl.fcla.edu/fcla/etd/SFE0001134.

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38

Ceresa, Claudia Carla. "Use of a three dimensional cell culture model to study airway smooth muscle - mast cell interactions in asthma." Thesis, University of Nottingham, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602487.

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Asthma is a disease that still causes a significant amount of morbidity and mortality in the UK. Airway smooth muscle hypertrophy and hyperplasia, with a corresponding infiltration by mast cells, are key features of the inflammatory process that results in airway remodelling and fixed airflow obstruction. A 3 dimensional collagen I model was developed to examine differences in airway smooth muscle cell morphology, phenotype and MMP 2 expression, when cultured in a 30 environment in comparison to a 20 monolayer. Using :: this technique, airway smooth muscle cells and HMC-1s, a mast cell line, ,
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39

Rate, Angela. "Epithelial cell regulation of dentritic cell maturation in the airway mucosa : studies in an in vitro model system." University of Western Australia. School of Paediatrics and Child Health, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0206.

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[Truncated abstract] Atopic asthma pathogenesis is driven by the combined effects of airway inflammation generated during responses to viral infections and aeroallergens, and both of these pathways are regulated by dendritic cells (DC) that differentiate locally from monocytic precursors. These DC normally exhibit a sentinel phenotype characterised by active antigen sampling but attenuated presentation capability, which limits the intensity of local expression of adaptive immunity. How this tight control of airway DC functions is normally maintained and why it breaks down in some atopics leadi
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40

Buckley, Tyra T. "Delivery of Asthma Management Services by a Federally Qualified Health Center in an Urban Setting." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/iph_theses/145.

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As a chronic disease, asthma presents a significant public health challenge nationally and in Georgia. In 2007, over 22 million people, including over 9 million children, had asthma in the United States. In Georgia, 230,000, or 10% of children have asthma, which is more prevalent among children less than 18 years of age than among adults. While asthma affects people of all ages and socioeconomic status, low income and minority populations have the highest asthma morbidity. This has proven to be the case with residents of Neighborhood Planning Unit V (NPU-V), a low-income minority communit
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41

LeBlanc, Lawrence Joseph. "CFD evaluation of cluster specific image based asthma lung features on particle transport and hygroscopic particle growth model validation." Thesis, University of Iowa, 2017. https://ir.uiowa.edu/etd/5546.

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Aerosolized drug delivery to the human lungs for asthma treatment has long been studied and yet the relationship between the delivery efficacy and the inter-subject variability due to gender, age, and disease severity remains unclear. A recent imaging-based cluster analysis on a population of asthmatic patients identifies four clusters with distinct structural and functional characteristics. The use of cluster membership to explore inter-subject variability by investigating numerically the air flow and particle transport in representative subjects of the asthmatic clusters on inhalation drug d
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42

Shaw, Ina. "Development of a management model for the treatment of asthma." Thesis, 2010. http://hdl.handle.net/10210/3220.

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D.Phil.<br>Asthma exemplifies a major medical concern and is a considerable cause of morbidity and mortality globally and in South Africa. Biokineticists have in the past primarily prescribed aerobic modes of exercise to asthmatics regardless of other modes of exercise that could be used in the management of asthma, each with their own unique benefits. The aim of this investigation was to develop a management model from a biokinetic perspective for the management of asthma in moderate, persistent asthmatics. The present study utilised a quantitative, comparative, research trial making use of a
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43

Chen, Sue Hsien, and 陳淑賢. "Effects of an Integrative Asthma Care Model on Primary Caregivers’ Asthma Management and Children’s Health Control." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/60147750576241290061.

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博士<br>長庚大學<br>臨床醫學研究所<br>101<br>Parents or primary caregivers play an important role in care with asthmatic children. Caregivers without adequate knowledge in asthma care may affect the disease control and delay treatment. The purpose of this study was to evaluate the effect of an integrative asthma care model , which in composition with empowerment concept on primary caregivers’ asthma management and children’s health control. The study was conducted from December 2010 to August 2012 in the outpatient department of a medical center in northern Taiwan. The study subjects included asthmatic chi
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44

Yu-Ling, Wu, and 吳玉琳. "The Immunoregulatory Effects of Propolis on Asthma Animal Model." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/95423893194043323558.

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碩士<br>輔仁大學<br>食品營養學系<br>91<br>The frequency of allergic diseases such as asthma has increased rapidly during the past decade. Many studies indicated that cytokines secretion pattern trend to Th2 (type 2 helper T cells) response were noted on asthma disease. The aim of this study will focus on the effects of propolis in the animal model of asthma. BALB/c female mice were divided into four groups including control group, low (1.3 mg/day) or high (6.5 mg/day) dose propolis group, and non-treat group which referred as the unimmunized group. Mice were immunized and sensitized expose to ovalbumin (O
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45

Kapeleris, Audrey. "The Role of Hepoxilins in an Asthma-like Mouse Model." Thesis, 2010. http://hdl.handle.net/1807/24586.

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Asthma is a chronic respiratory illness where the airway occasionally constricts, becomes inflamed, and is lined with excessive amounts of mucus. There are many lipid mediators involved in this inflammatory response. Hepoxilins are biologically active hydroxyepoxy eicosatrienoic acid metabolites of arachidonic acid, formed through the 12-lipoxygenase pathway. Our goal in this study was to identify if hepoxilins had a direct effect on smooth muscle contractions, to identify the source of hepoxilins in asthmatic-like mouse model, and to determine if blocking this pathway reduced inflammation ass
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46

Jui-ChangLiu and 劉瑞璋. "The effects of atorvastatin on foamy macrophage inchronic asthma mouse model." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/s3ngxw.

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47

Tatari, Nazanin. "The effect of semaphorin 3E on angiogenesis in murine model of allergic asthma." 2015. http://hdl.handle.net/1993/30967.

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Increased angiogenesis is an important characteristic of remodeling in asthmatic airways which stems from the imbalance between pro-angiogenic and anti-angiogenic factors. Surprisingly, the factors regulating this process in allergic asthma are poorly defined. The focus of this thesis is to investigate the effect of Semaphorin 3E (Sema3E) on angiogenesis events within the airways of murine model of allergic asthma. The role of Sema3E in asthma angiogenesis was tested in wild type and Sema3e-/- mice exposed to House Dust Mite (HDM) and monitored for changes in blood vessels number in the lung
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48

Herbert, Cristan Medical Sciences Faculty of Medicine UNSW. "Effects of glucocorticoid and phosphodiesterase-4 inhibitor therapy in a mouse model of chronic asthma." 2007. http://handle.unsw.edu.au/1959.4/40535.

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Asthma is a chronic inflammatory disease of the airways. Using a murine model which replicates many characteristic features of human asthma, this study evaluated the effects of treatment with anti-inflammatory drugs on the lesions of chronic asthma, and investigated potential underlying molecular mechanisms. Treatment with dexamethasone, a glucocorticoid, was compared with roflumilast, a novel phosphodiesterase-4 (PDE4) inhibitor. BALB/c mice sensitised to ovalbumin were challenged with a low mass concentration of aerosolised antigen for 30 min/day, 3 days/week for 6 weeks. In weeks 5 and 6, g
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49

Wu, Cheng-Kuan, and 胡靜君. "Inhalation Toxicity of Silver Nanoparticles in a Murine Model of Allergic Asthma." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/77311361258258222393.

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碩士<br>國立臺灣大學<br>環境衛生研究所<br>101<br>Nowadays, asthma is one of the most common airway inflammatory disease and its prevalence is high in developed and developing countries. A wide range of silver nanoparticle applications has emerged in consumer products ranging from disinfecting medical devices to water treatment. We are interested in the inhalation toxicity of silver nanoparticles in susceptible allergic asthmatic mice. In this study, silver nanoparticles were produced in a generation system. The BALB/c mice were divided into normal group (PBS) and asthmatic group (induced by OVA injection). T
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50

Chen, Shew-Dan, and 陳秀丹. "Acute effect of methylprednisolone on brain in a rat model of asthma." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/69451809938767052212.

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碩士<br>國立陽明大學<br>急重症醫學研究所<br>96<br>Abstract Asthma affects not only the airways but also the central nervous system (CNS). Corticosteroids are effective therapeutic agents for asthma. In our study, we investigated the acute effect of ovalbumin (OVA) on the brain and the effectiveness of methylprednisolone (MP) in both the periphery and CNS in a rat model of allergic asthma. Rats sensitized to OVA and exposed to OVA aerosol challenge to induce allergic asthma were compared with control rats and rats sensitized to OVA and pretreated with MP before OVA ex
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