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Journal articles on the topic 'Atmospheric Pressure Chemical Ionization'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Rebane, Riin, Anneli Kruve, Piia Liigand, Jaanus Liigand, Koit Herodes, and Ivo Leito. "Establishing Atmospheric Pressure Chemical Ionization Efficiency Scale." Analytical Chemistry 88, no. 7 (2016): 3435–39. http://dx.doi.org/10.1021/acs.analchem.5b04852.

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2

Pitman, Ciara N., and William R. LaCourse. "Desorption atmospheric pressure chemical ionization: A review." Analytica Chimica Acta 1130 (September 2020): 146–54. http://dx.doi.org/10.1016/j.aca.2020.05.073.

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3

Chen, Lee Chuin, Md Matiur Rahman, and Kenzo Hiraoka. "Super-atmospheric pressure chemical ionization mass spectrometry." Journal of Mass Spectrometry 48, no. 3 (2013): 392–98. http://dx.doi.org/10.1002/jms.3173.

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4

Sedláčková, Simona, Martin Hubálek, Vladimír Vrkoslav, Miroslava Blechová, and Josef Cvačka. "Utility of Atmospheric-Pressure Chemical Ionization and Photoionization Mass Spectrometry in Bottom-Up Proteomics." Separations 9, no. 2 (2022): 42. http://dx.doi.org/10.3390/separations9020042.

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In a typical bottom-up proteomics workflow, proteins are enzymatically cleaved, and the resulting peptides are analyzed by HPLC with electrospray ionization (ESI) tandem mass spectrometry. This approach is practical and widely applied. It has, however, limitations mostly related to less efficient or even inefficient ionization of some peptides in ESI sources. Gas-phase ionization methods like atmospheric-pressure chemical ionization (APCI) or atmospheric-pressure photoionization (APPI) offer alternative ways of detecting various analytes. This work is a systematic study of the ionization effic

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5

Bartosińska, Ewa, Agnieszka Borsuk-De Moor, Danuta Siluk, Michał J. Markuszewski, and Paweł Wiczling. "Ionization of tocopherols and tocotrienols in atmospheric pressure chemical ionization." Rapid Communications in Mass Spectrometry 32, no. 11 (2018): 919–27. http://dx.doi.org/10.1002/rcm.8124.

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6

Brophy, Patrick, and Delphine K. Farmer. "Clustering, methodology, and mechanistic insights into acetate chemical ionization using high-resolution time-of-flight mass spectrometry." Atmospheric Measurement Techniques 9, no. 8 (2016): 3969–86. http://dx.doi.org/10.5194/amt-9-3969-2016.

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Abstract. We present a comprehensive characterization of cluster control and transmission through the Tofwerk atmospheric pressure interface installed on various chemical ionization time-of-flight mass spectrometers using authentic standards. This characterization of the atmospheric pressure interface allows for a detailed investigation of the acetate chemical ionization mechanisms and the impact of controlling these mechanisms on sensitivity, selectivity, and mass spectral ambiguity with the aim of non-targeted analysis. Chemical ionization with acetate reagent ions is controlled by a distrib

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7

Jjunju, Fred P. M., Abraham K. Badu-Tawiah, Anyin Li, Santosh Soparawalla, Iman S. Roqan, and R. Graham Cooks. "Hydrocarbon analysis using desorption atmospheric pressure chemical ionization." International Journal of Mass Spectrometry 345-347 (July 2013): 80–88. http://dx.doi.org/10.1016/j.ijms.2012.08.030.

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8

Cristoni, Simone, Luigi Rossi Bernardi, Ida Biunno, Michela Tubaro, and Federico Guidugli. "Surface-activated no-discharge atmospheric pressure chemical ionization." Rapid Communications in Mass Spectrometry 17, no. 17 (2003): 1973–81. http://dx.doi.org/10.1002/rcm.1141.

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9

Cheng, Sy-Chyi, Yen-Ting Chen, Siou-Sian Jhang, and Jentaie Shiea. "Flame-induced atmospheric pressure chemical ionization mass spectrometry." Rapid Communications in Mass Spectrometry 30, no. 7 (2016): 890–96. http://dx.doi.org/10.1002/rcm.7516.

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10

Sun, Qian, Jianghong Gu, Brian R. Stolze, and Steven J. Soldin. "Atmospheric Pressure Chemical Ionization Is a Suboptimal Ionization Source for Steroids." Clinical Chemistry 64, no. 6 (2018): 974–76. http://dx.doi.org/10.1373/clinchem.2018.287029.

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11

Michalczuk, Bartosz, Ladislav Moravský, Peter Papp, Pavel Mach, Martin Sabo, and Štefan Matejčík. "Isomer and conformer selective atmospheric pressure chemical ionisation of dimethyl phthalate." Physical Chemistry Chemical Physics 21, no. 25 (2019): 13679–85. http://dx.doi.org/10.1039/c9cp02069a.

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The ionization mechanism of Atmospheric Pressure Chemical Ionization (APCI) for dimethyl phthalate isomers using an Ion Mobility Spectrometry (IMS) experiment combined with Density Functional Theory (DFT) calculations.

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12

Rissanen, Matti P., Jyri Mikkilä, Siddharth Iyer, and Jani Hakala. "Multi-scheme chemical ionization inlet (MION) for fast switching of reagent ion chemistry in atmospheric pressure chemical ionization mass spectrometry (CIMS) applications." Atmospheric Measurement Techniques 12, no. 12 (2019): 6635–46. http://dx.doi.org/10.5194/amt-12-6635-2019.

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Abstract. A novel chemical ionization inlet named the Multi-scheme chemical IONization inlet (MION), Karsa Ltd., Helsinki, Finland) capable of fast switching between multiple reagent ion schemes is presented, and its performance is demonstrated by measuring several known oxidation products from much-studied cyclohexene and α-pinene ozonolysis systems by applying consecutive bromide (Br−) and nitrate (NO3-) chemical ionization. Experiments were performed in flow tube reactors under atmospheric pressure and room temperature (22 ∘C) utilizing an atmospheric pressure interface time-of-flight mass

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13

Eiceman, G. A., J. F. Bergloff, J. E. Rodriguez, W. Munro, and Z. Karpas. "Atmospheric pressure chemical ionization of fluorinated phenols in atmospheric pressure chemical ionization mass spectrometry, tandem mass spectrometry, and ion mobility spectrometry." Journal of the American Society for Mass Spectrometry 10, no. 11 (1999): 1157–65. http://dx.doi.org/10.1016/s1044-0305(99)00082-3.

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14

Kemmo, S., V. Ollilainen, Lampi A-M, and V. Piironen. "Determination of stigmasterol hydroperoxides using high-performance liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization." Czech Journal of Food Sciences 22, SI - Chem. Reactions in Foods V (2004): S144—S146. http://dx.doi.org/10.17221/10639-cjfs.

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A new specific method using high-performance liquid chromatography-mass spectrometry (HPLC-MS) for the detection of stigmasterol hydroperoxides was developed. Hydroperoxides of stigmasterol were obtained by photo-oxidation (90 min) in the presence of methylene blue as a sensitizer. The separation was performed using normal-phase chromatographic conditions. The MS detection was carried out with an ion-trap mass spectrometer using atmospheric pressure chemical ionization (APCI) and positive ion mode. Stigmasterol hydroperoxides were seen to produce no protonated molecular ions [M + H]<sup>

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15

Cai, Sheng-Suan, and Jack A. Syage. "Comparison of Atmospheric Pressure Photoionization, Atmospheric Pressure Chemical Ionization, and Electrospray Ionization Mass Spectrometry for Analysis of Lipids." Analytical Chemistry 78, no. 4 (2006): 1191–99. http://dx.doi.org/10.1021/ac0515834.

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16

Strnad, Štěpán, Vladimír Vrkoslav, and Josef Cvačka. "Location of Double or Triple Bonds in Lipids Using Mass Spectrometry, Part II." Chemické listy 117, no. 12 (2023): 747–54. http://dx.doi.org/10.54779/chl20230747.

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This text is the second part of a review article on advances in mass spectrometry for characterizing double and triple bonds in lipid acyl chains by LC-MS and direct ionization of liquid samples at atmospheric pressure. It is devoted to epoxidation, forming adducts from acetonitrile during atmospheric pressure chemical ionization, photodissociation, and electron-ion reaction-based dissociations.

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17

Kauppila, T. J., T. Nikkola, R. A. Ketola, and R. Kostiainen. "Atmospheric pressure photoionization-mass spectrometry and atmospheric pressure chemical ionization-mass spectrometry of neurotransmitters." Journal of Mass Spectrometry 41, no. 6 (2006): 781–89. http://dx.doi.org/10.1002/jms.1034.

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18

Vaikkinen, Anu, Tiina J. Kauppila, and Risto Kostiainen. "Charge Exchange Reaction in Dopant-Assisted Atmospheric Pressure Chemical Ionization and Atmospheric Pressure Photoionization." Journal of The American Society for Mass Spectrometry 27, no. 8 (2016): 1291–300. http://dx.doi.org/10.1007/s13361-016-1399-8.

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19

KUDAKA, Ichiro, Yasuo KATUNO, Youichiro FURUKAWA, Akio OKAMOTO, and Kenzo HIRAOKA. "Mass Spectrometry of Polydimethylsiloxanes with Atmospheric Pressure Chemical Ionization." Journal of the Mass Spectrometry Society of Japan 45, no. 5 (1997): 591–602. http://dx.doi.org/10.5702/massspec.45.591.

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20

Östman, Pekka, Seppo J. Marttila, Tapio Kotiaho, Sami Franssila, and Risto Kostiainen. "Microchip Atmospheric Pressure Chemical Ionization Source for Mass Spectrometry." Analytical Chemistry 76, no. 22 (2004): 6659–64. http://dx.doi.org/10.1021/ac049345g.

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21

Östman, Pekka, Laura Luosujärvi, Markus Haapala, et al. "Gas Chromatography-Microchip Atmospheric Pressure Chemical Ionization-Mass Spectrometry." Analytical Chemistry 78, no. 9 (2006): 3027–31. http://dx.doi.org/10.1021/ac052260a.

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22

van Breemen, Richard B., Linlin Dong, and Natasa D. Pajkovic. "Atmospheric pressure chemical ionization tandem mass spectrometry of carotenoids." International Journal of Mass Spectrometry 312 (February 2012): 163–72. http://dx.doi.org/10.1016/j.ijms.2011.07.030.

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23

Bell, Suzanne Ehart, Robert G. Ewing, Gary A. Eiceman, and Zeev Karpas. "Atmospheric pressure chemical ionization of alkanes, alkenes, and cycloalkanes." Journal of the American Society for Mass Spectrometry 5, no. 3 (1994): 177–85. http://dx.doi.org/10.1016/1044-0305(94)85031-3.

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24

Makas, A. L., M. L. Troshkov, A. S. Kudryavtsev, and V. M. Lunin. "Miniaturized mass-selective detector with atmospheric pressure chemical ionization." Journal of Chromatography B 800, no. 1-2 (2004): 63–67. http://dx.doi.org/10.1016/j.jchromb.2003.08.053.

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25

Klee, Sonja, Marco Thinius, Klaus J. Brockmann, and Thorsten Benter. "Capillary atmospheric pressure chemical ionization using liquid point electrodes." Rapid Communications in Mass Spectrometry 28, no. 14 (2014): 1591–600. http://dx.doi.org/10.1002/rcm.6944.

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26

Eichenberger, Silvan, Michaël Méret, Stefan Bienz, and Laurent Bigler. "Decomposition ofN-hydroxylated compounds during atmospheric pressure chemical ionization." Journal of Mass Spectrometry 45, no. 2 (2010): 190–97. http://dx.doi.org/10.1002/jms.1703.

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27

Imbert, Laurent, Mathieu Gaudin, Danielle Libong, et al. "Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for a lipidomic analysis of Leishmania donovani." Journal of Chromatography A 1242 (June 2012): 75–83. http://dx.doi.org/10.1016/j.chroma.2012.04.035.

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28

Pudenzi, Marcos A., and Marcos N. Eberlin. "Assessing Relative Electrospray Ionization, Atmospheric Pressure Photoionization, Atmospheric Pressure Chemical Ionization, and Atmospheric Pressure Photo- and Chemical Ionization Efficiencies in Mass Spectrometry Petroleomic Analysis via Pools and Pairs of Selected Polar Compound Standards." Energy & Fuels 30, no. 9 (2016): 7125–33. http://dx.doi.org/10.1021/acs.energyfuels.6b01403.

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29

Andrade, Francisco J., Jacob T. Shelley, William C. Wetzel, et al. "Atmospheric Pressure Chemical Ionization Source. 1. Ionization of Compounds in the Gas Phase." Analytical Chemistry 80, no. 8 (2008): 2646–53. http://dx.doi.org/10.1021/ac800156y.

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30

Lien, Guang-Wen, Chia-Yang Chen, and Gen-Shuh Wang. "Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for determining estrogenic chemicals in water by liquid chromatography tandem mass spectrometry with chemical derivatizations." Journal of Chromatography A 1216, no. 6 (2009): 956–66. http://dx.doi.org/10.1016/j.chroma.2008.12.023.

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31

Chingin, Konstantin, Juchao Liang, Yaping Hang, Longhua Hu, and Huanwen Chen. "Rapid recognition of bacteremia in humans using atmospheric pressure chemical ionization mass spectrometry of volatiles emitted by blood cultures." RSC Advances 5, no. 18 (2015): 13952–57. http://dx.doi.org/10.1039/c4ra16502k.

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32

Östman, Pekka, Sirkku Jäntti, Kestas Grigoras, et al. "Capillary liquid chromatography–microchip atmospheric pressure chemical ionization–mass spectrometry." Lab Chip 6, no. 7 (2006): 948–53. http://dx.doi.org/10.1039/b601290f.

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33

Takada, Yasuaki, Minoru Sakairi, and Hideaki Koizumi. "Atmospheric Pressure Chemical Ionization Interface for Capillary Electrophoresis/Mass Spectrometry." Analytical Chemistry 67, no. 8 (1995): 1474–76. http://dx.doi.org/10.1021/ac00104a027.

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34

Choi, Sung-Seen, and Ok-Bae Kim. "Fragmentation of deprotonated amino acids in atmospheric pressure chemical ionization." International Journal of Mass Spectrometry 338 (March 2013): 17–22. http://dx.doi.org/10.1016/j.ijms.2013.01.006.

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35

Karst, Uwe. "Liquid chromatography–electron capture–atmospheric pressure chemical ionization-mass spectrometry." Analytical and Bioanalytical Chemistry 382, no. 8 (2005): 1744–46. http://dx.doi.org/10.1007/s00216-005-3328-8.

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36

Byrdwell, William Craig. "Atmospheric pressure chemical ionization mass spectrometry for analysis of lipids." Lipids 36, no. 4 (2001): 327–46. http://dx.doi.org/10.1007/s11745-001-0725-5.

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37

Mayer, Thomas, and Helko Borsdorf. "Mutual influences of halogenated compounds during atmospheric pressure chemical ionization." International Journal for Ion Mobility Spectrometry 16, no. 3 (2013): 229–35. http://dx.doi.org/10.1007/s12127-013-0132-6.

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38

Byrdwell, Wm Craig, and Edward A. Emken. "Analysis of triglycerides using atmospheric pressure chemical ionization mass spectrometry." Lipids 30, no. 2 (1995): 173–75. http://dx.doi.org/10.1007/bf02538272.

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39

Gao, Jinshan, David J. Borton, Benjamin C. Owen, et al. "Laser-Induced Acoustic Desorption/Atmospheric Pressure Chemical Ionization Mass Spectrometry." Journal of The American Society for Mass Spectrometry 22, no. 3 (2011): 531–38. http://dx.doi.org/10.1007/s13361-010-0048-x.

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40

Riva, Matthieu, Veronika Pospisilova, Carla Frege, et al. "Evaluation of a reduced-pressure chemical ion reactor utilizing adduct ionization for the detection of gaseous organic and inorganic species." Atmospheric Measurement Techniques 17, no. 19 (2024): 5887–901. http://dx.doi.org/10.5194/amt-17-5887-2024.

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Abstract. Volatile organic compounds (VOCs) and volatile inorganic compounds (VICs) provide critical information across many scientific fields including atmospheric chemistry and soil and biological processes. Chemical ionization (CI) mass spectrometry has become a powerful tool for tracking these chemically complex and temporally variable compounds in a variety of laboratory and field environments. It is particularly powerful with time-of-flight mass spectrometers, which can measure hundreds of compounds in a fraction of a second and have enabled entirely new branches of VOC and/or VIC resear

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41

Benoit, Roland, Nesrine Belhadj, Zahraa Dbouk, Maxence Lailliau та Philippe Dagaut. "On the formation of highly oxidized pollutants by autoxidation of terpenes under low-temperature-combustion conditions: the case of limonene and α-pinene". Atmospheric Chemistry and Physics 23, № 10 (2023): 5715–33. http://dx.doi.org/10.5194/acp-23-5715-2023.

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Abstract. The oxidation of monoterpenes under atmospheric conditions has been the subject of numerous studies. They were motivated by the formation of oxidized organic molecules (OOMs), which, due to their low vapor pressure, contribute to the formation of secondary organic aerosols (SOA). Among the different reaction mechanisms proposed for the formation of these oxidized chemical compounds, it appears that the autoxidation mechanism, involving successive events of O2 addition and H migration, common to both low-temperature-combustion and atmospheric conditions, leads to the formation of high

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42

Huang, De-Yi, Meng-Jiy Wang, Jih-Jen Wu, and Yu-Chie Chen. "Ionization of Volatile Organics and Nonvolatile Biomolecules Directly from a Titanium Slab for Mass Spectrometric Analysis." Molecules 26, no. 22 (2021): 6760. http://dx.doi.org/10.3390/molecules26226760.

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Atmospheric pressure chemical ionization (APCI)-mass spectrometry (MS) and electrospray ionization (ESI)-MS can cover the analysis of analytes from low to high polarities. Thus, an ion source that possesses these two ionization functions is useful. Atmospheric surface-assisted ionization (ASAI), which can be used to ionize polar and nonpolar analytes in vapor, liquid, and solid forms, was demonstrated in this study. The ionization of analytes through APCI or ESI was induced from the surface of a metal substrate such as a titanium slab. ASAI is a contactless approach operated at atmospheric pre

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43

Wang, Ganfeng, Yunsheng Hsieh, and Walter A. Korfmacher. "Comparison of Atmospheric Pressure Chemical Ionization, Electrospray Ionization, and Atmospheric Pressure Photoionization for the Determination of Cyclosporin A in Rat Plasma." Analytical Chemistry 77, no. 2 (2005): 541–48. http://dx.doi.org/10.1021/ac040144m.

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44

Sedláčková, Simona, Martin Hubálek, Vladimír Vrkoslav, Miroslava Blechová, Petr Kozlík, and Josef Cvačka. "Positive Effect of Acetylation on Proteomic Analysis Based on Liquid Chromatography with Atmospheric Pressure Chemical Ionization and Photoionization Mass Spectrometry." Molecules 28, no. 9 (2023): 3711. http://dx.doi.org/10.3390/molecules28093711.

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A typical bottom-up proteomic workflow comprises sample digestion with trypsin, separation of the hydrolysate using reversed-phase HPLC, and detection of peptides via electrospray ionization (ESI) tandem mass spectrometry. Despite the advantages and wide usage of protein identification and quantification, the procedure has limitations. Some domains or parts of the proteins may remain inadequately described due to inefficient detection of certain peptides. This study presents an alternative approach based on sample acetylation and mass spectrometry with atmospheric pressure chemical ionization

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45

Lipok, Christian, Florian Uteschil, and Oliver J. Schmitz. "Development of an Atmospheric Pressure Chemical Ionization Interface for GC-MS." Molecules 25, no. 14 (2020): 3253. http://dx.doi.org/10.3390/molecules25143253.

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A closed atmospheric pressure chemical ionization (APCI) ion source as interface between a gas chromatograph (GC) and a triple quadrupole mass spectrometer (QqQ-MS) was developed. The influence of different ion source conditions, such as humidity, make-up gas flow, and the position of the GC column, were investigated and determined as main factors to increase sensitivity and repeatability of the system. For a performance test under real conditions, the new APCI ion source was used for the determination of plant protection products in commercially available coffee beans from Vietnam. The ioniza

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46

Leinonen, Antti, Tiia Kuuranne, and Risto Kostiainen. "Liquid chromatography/mass spectrometry in anabolic steroid analysis?optimization and comparison of three ionization techniques: electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization." Journal of Mass Spectrometry 37, no. 7 (2002): 693–98. http://dx.doi.org/10.1002/jms.328.

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47

Sui, Xinyi, Julio E. Terán, Chengcheng Feng, Killian Wustrow, Caroline J. Smith, and Nelson R. Vinueza. "Quantification of anthracene after dermal absorption test via APCI-tandem mass spectrometry." Analytical Methods 12, no. 22 (2020): 2820–26. http://dx.doi.org/10.1039/d0ay00486c.

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48

Islam, Syful, Md Badrul Alam, Hyeon-Jin Ann, Ji-Hyun Park, Sang-Han Lee та Sunghwan Kim. "Metabolite Profiling of Manilkara zapota L. Leaves by High-Resolution Mass Spectrometry Coupled with ESI and APCI and In Vitro Antioxidant Activity, α-Glucosidase, and Elastase Inhibition Assays". International Journal of Molecular Sciences 22, № 1 (2020): 132. http://dx.doi.org/10.3390/ijms22010132.

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High-resolution mass spectrometry equipped with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources was used to enhance the characterization of phytochemicals of ethanol extracts of Manilkara zapota L. leaves (ZLE). Sugar compounds, dicarboxylic acids, compounds of phenolic acids and flavonoids groups, and other phytochemicals were detected from the leaves. Antioxidant activity and inhibition potentiality of ZLE against α-glucosidase enzyme, and elastase enzyme activities were evaluated in in vitro analysis. ZLE significantly inhibited activities of α-gluc

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49

Lesniewski, Joseph E., William P. McMahon, Kunyu Zheng, Haopeng Wang, Hamid Badiei, and Kaveh Jorabchi. "Atmospheric pressure plasma assisted reaction chemical ionization for analysis of chlorinated compounds separated by liquid chromatography." Journal of Analytical Atomic Spectrometry 32, no. 9 (2017): 1757–65. http://dx.doi.org/10.1039/c7ja00115k.

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We report development of an atmospheric pressure plasma assisted reaction chemical ionization (PARCI) source with liquid sample introduction, enabling high sensitivity detection of chlorine in LC-separated compounds.

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50

Rauha, Jussi-Pekka, Heikki Vuorela, and Risto Kostiainen. "Effect of eluent on the ionization efficiency of flavonoids by ion spray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization mass spectrometry." Journal of Mass Spectrometry 36, no. 12 (2001): 1269–80. http://dx.doi.org/10.1002/jms.231.

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