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Journal articles on the topic 'Atracurium Besylate'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Biswas, Rajat Kumar, Karuna Kumar Das, and Arbind Kumar Ray. "Comparison of Haemodynamic Parameters between Atracurium and Cisatracurium during General Anaesthesia in Abdominal Surgeries." IFR Journal of Medicine and Surgery 2, no. 2 (2025): 38–45. https://doi.org/10.5281/zenodo.15547965.

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Background: Atracurium Besylate and Cisatracurium Besylate both belong to Benzoylisoquinolium group of Non-depolarizing Muscle relaxant. In fact, Cisatracurium is the 1R-cis, 1’R-cis isomer of Atracurium. Both have distinct chemical properties regarding onset time, potency, histamine release etc. despite their structural similarity. Objectives: The research aimed to assess and compare the efficacy of 0.5mg/Kg IV Atracurium (twice the ED95) as opposed to 0.15 mg/Kg IV Cisatracurium (thrice the ED95) for intubation, focusing on intubation conditions and haemodynamic changes during general

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2

Gill, S. S. "Weight-determined dosage of atracurium besylate." Anaesthesia 44, no. 12 (1989): 1011–12. http://dx.doi.org/10.1111/j.1365-2044.1989.tb09235.x.

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3

Guimarães, Celeste B., Luciane Albuquerque, Marcela Torikachvili, et al. "Effects of atracurium besylate on corneal endothelium of chickens: in vitro study." Pesquisa Veterinária Brasileira 39, no. 1 (2019): 70–74. http://dx.doi.org/10.1590/1678-5150-pvb-5595.

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ABSTRACT: The aim of this study was to investigate the acute effects of atracurium besylate on cellular damage in corneal endothelium of chickens. Twenty healthy chicken eyes were assigned to the following groups: Group 1 (G1), experimental group (n=10); and Group 2 (G2), control (n=10). Excised corneoscleral buttons were immediately placed on glass microscopy slides with endothelial region faced up. Corneal endothelium of eyes in G1 were covered with AB (0.2mL, 10mg/mL) for 3 min and then rinsed with balanced salt solution (BSS), while the corneal endothelium of eyes in G2 were covered with B

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4

Bakhshi, Dr Rochana G. "Comparison of Neuromuscular Blockade and Recovery Characterstics of Cisatracurium Besylate versus Atracurium Besylate in Adult Surgical Patients." Journal of Medical Science And clinical Research 04, no. 12 (2016): 14613–21. http://dx.doi.org/10.18535/jmscr/v4i12.52.

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5

BOHEIMER, N., J. W. HARRIS, and S. WARD. "Neuromuscular blockade in dystrophia myotonica with atracurium besylate." Anaesthesia 40, no. 9 (1985): 872–74. http://dx.doi.org/10.1111/j.1365-2044.1985.tb11048.x.

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6

Santika, Suparno Adi, Djujuk Rahmat Basuki, and Karmini Karmini. "Perbandingan Waktu Pemberian Atrakurium Besylate Intravena 0,5 mg/kgbb 5 Detik dan 90 Detik Terhadap Peningkatan Nadi Saat Induksi Anestesi Umum di Rumah Sakit Saiful Anwar Malang." JAI (Jurnal Anestesiologi Indonesia) 7, no. 1 (2018): 42. http://dx.doi.org/10.14710/jai.v7i1.9165.

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Latar Belakang : Atracurium besylate, merupakan obat pelumpuh otot nondepolarisasi kelas bisquaternary benzylisoquinolinium yang menghasilkan beberapa efek samping selama uji klinis luas di berbagai penelitian, berupa pelepasan histamin yang dikaitkan dengan refleks takikardia, hipotensi berat dan ruam pada pengamatan klinis. Beberapa kasus reaksi anafilaksis parah dilaporkan setelah injeksi atrakurium, menyebabkan komplikasi yang mengancam jiwa. Pemberian lambat injeksi Atrakurium besylate, menurunkan manifestasi refleks peningkatan nadi. Tujuan penelitian ini adalah untuk mengetahui, perband

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7

Nicholson, Anthony, and Jan E. Ilkiw. "Neuromuscular and cardiovascular effects of atracurium in isoflurane-anesthetized chickens." American Journal of Veterinary Research 53, no. 12 (1992): 2337–42. http://dx.doi.org/10.2460/ajvr.1992.53.12.2337.

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Summary Atracurium besylate, a nondepolarizing neuromuscular blocking agent, was administered to 24 isoflurane-anesthetized domestic chickens. Birds were randomly assigned to 4 groups, and atracurium was administered at dosage of 0.15, 0.25, 0.35 or 0.45 mg/kg of body weight. The time of onset of twitch depression, the amount of maximal twitch depression, and the duration of muscular relaxation were recorded. After return to control twitch height, atracurium was further administered to achieve > 75% twitch depression. When twitch depression reached 75% during noninduced recovery, 0 5 mg of

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8

Graystone, S., M. F. Wells, and D. J. Farrell. "Do Intensive Care Drug Infusions Support Microbial Growth?" Anaesthesia and Intensive Care 25, no. 6 (1997): 640–42. http://dx.doi.org/10.1177/0310057x9702500608.

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The potential for commonly infused drug solutions to support or inhibit microbial growth was explored in this study. Drugs examined were midazolam HCl, morphine sulphate, fentanyl citrate, pethidine HCl, bupivacaine HCl, atracurium besylate, vecuronium bromide, adrenaline, dopamine, dobutamine, noradrenaline, isoprenaline, glyceryl trinitrate, sodium nitroprusside and propofol. All drugs were studied in both diluted and undiluted forms. Of the 15 medications investigated, all except propofol were found to be bactericidal and to reduce fungal growth.

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9

Hariharan, Uma, Shagun Bhatia Shah, and Ajay Kumar Bhargava. "Local allergic reaction to atracurium besylate: an uncommon and unique reason." Journal of Anesthesiology and Clinical Science 4, no. 1 (2015): 6. http://dx.doi.org/10.7243/2049-9752-4-6.

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10

Shorten, G. D., and N. M. Gibbs. "Dose-response relationship of atracurium besylate in the halothaneana-esthetised pig." Research in Veterinary Science 55, no. 3 (1993): 392–93. http://dx.doi.org/10.1016/0034-5288(93)90116-w.

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11

Murphy, D. F., and J. B. Magner. "Neuromuscular blockade with atracurium besylate in a patient with myasthenia gravis." Irish Journal of Medical Science 155, no. 6 (1986): 202–3. http://dx.doi.org/10.1007/bf02939843.

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12

Kim, Joung Uk, Po Sun Kang, Hae Ja Lim, and Suk Min Yoon. "The Clinical Evaluation of Atracurium Besylate for Endotracheal Intubation for Cesarean Section." Korean Journal of Anesthesiology 25, no. 5 (1992): 970. http://dx.doi.org/10.4097/kjae.1992.25.5.970.

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13

Pramar, Y. V., V. A. Loucas, and D. Word. "Chemical stability and adsorption of atracurium besylate injections in disposable plastic syringes." Journal of Clinical Pharmacy and Therapeutics 21, no. 3 (1996): 173–75. http://dx.doi.org/10.1111/j.1365-2710.1996.tb00018.x.

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14

Garrison, Bonnie. "Atracurium besylate: Does it have a place in the helicopter drug box?" AeroMedical Journal 1, no. 5 (1986): 14. http://dx.doi.org/10.1016/s0894-8321(86)80028-6.

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15

Bernstain U. Chitkara, H. H., H. Plosker, M. Gettes, and R. L. Berkowitz. "Use of Atracurium Besylate to Arrest Fetal Activity During Intrauterine Intravascular Transfusion." Obstetric Anesthesia Digest 9, no. 2 (1989): 108. http://dx.doi.org/10.1097/00132582-198907000-00059.

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16

Schopfer, C., J. F. Pittet, D. R. Morel, E. Tassonyi, and A. Benakis. "Pharmacokinetics of atracurium besylate in the pig after a single i.v. injection." European Journal of Drug Metabolism and Pharmacokinetics 14, no. 4 (1989): 299–302. http://dx.doi.org/10.1007/bf03190115.

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17

Hildebrand, S. V., G. A. Howitt, and D. Arpin. "Neuromuscular and cardiovascular effects of atracurium in ponies anesthetized with halothane." American Journal of Veterinary Research 47, no. 5 (1986): 1096–100. https://doi.org/10.2460/ajvr.1986.47.05.1096.

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SUMMARY Atracurium besylate, a recently developed, intermediate-duration acting, neuromuscular-blocking agent, was given to 15 halothane-anesthetized ponies to produce surgical relaxation (95% to 99% reduction of hoof twitch). All 15 ponies were given 3 injections; 8 of the 15 ponies were given 2 additional injections. Initial dosage of 0.11 ± 0.01 mg/kg (mean ± sd) and all subsequent injections of 0.052 mg/kg produced desired relaxation. Paralysis phase (maximum twitch reduction to 10% twitch recovery) lasted 24 ± 5 minutes for the initial injection. Paralysis from subsequent injections laste

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18

Ilkiw, J. E., S. F. Forsyth, T. Hill, and C. R. Gregory. "Atracurium administration, as an infusion, to induce neuromuscular blockade in clinically normal and temporarily immune-suppressed cats." Journal of the American Veterinary Medical Association 197, no. 9 (1990): 1153–56. http://dx.doi.org/10.2460/javma.1990.197.09.1153.

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Summary Atracurium besylate, a nondepolarizing neuromuscular blocking agent, was administered by infusion to 10 cats that were anesthetized with isoflurane and oxygen to allow transplantation of a myocutaneous flap. Five of the cats were given cyclosporine (20 mg/kg of body weight, po, q 12 h in divided doses) for 2 days prior to anesthesia, and prednisolone (0.25 mg/kg, po) on the morning of surgery. The other 5 cats were not given either drug. Neuromuscular blockade was assessed, using the train-of-four stimulation, and throughout surgery, the infusion rate was adjusted to maintain the first

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19

Galluzzi, F., F. Rensis, A. Menozzi, and G. Spattini. "Effect of intraurethral administration of atracurium besylate in male cats with urethral plugs." Journal of Small Animal Practice 53, no. 7 (2012): 411–15. http://dx.doi.org/10.1111/j.1748-5827.2012.01239.x.

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20

Rosa, Giovanni, Paolo Orfei, Maria Sanfilippo, Vincenzo Vilardi, and Alessandro Gasparetto. "The Effects of Atracurium Besylate (Tracrium??) on Intracranial Pressure and Cerebral Perfusion Pressure." Anesthesia & Analgesia 65, no. 4 (1986): 381???384. http://dx.doi.org/10.1213/00000539-198604000-00014.

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21

Forsyth, Sandra F., Jan E. Ilkiw, and Susan V. Hildebrand. "Effect of gentamicin administration on the neuromuscular blockade induced by atracurium in cats." American Journal of Veterinary Research 51, no. 10 (1990): 1675–78. http://dx.doi.org/10.2460/ajvr.1990.51.10.1675.

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SUMMARY Atracurium besylate, a nondepolarizing neuromuscular blocking agent, was administered as an infusion to 8 anesthetized cats in which neuromuscular blockade was assessed, using the train-of-four response. Once 50% depression of the first-twitch (T1) response was achieved, the infusion was held constant for 60 minutes before being discontinued and the recovery time was determined. The time for recovery was recorded as the time for the train-of-four ratio (T4 ratio) to increase from 50% to 75%. After-recovery, atracurium infusion was reinstituted and the cats were again maintained for 60

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22

Spina, Raffaella, Dillon M. Voss, Laura Asnaghi, Andrew Sloan, and Eli E. Bar. "Atracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cells." Oncotarget 7, no. 1 (2015): 459–72. http://dx.doi.org/10.18632/oncotarget.6314.

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23

Gussack, Gerald S., Robert F. Evans, and Ernest J. Tacchi. "Intravenous Anesthesia and Jet Ventilation for Laser Microlaryngeal Surgery." Annals of Otology, Rhinology & Laryngology 96, no. 1 (1987): 29–33. http://dx.doi.org/10.1177/000348948709600107.

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Competition between otolaryngologists and anesthesiologists for the limited space of the airway results in compromised control for both concerns. The surgeon desires an unobstructed view, whereas the anesthesiologist must ensure adequate ventilation. The drawbacks of standard methods include inadequate airways, inadequate visualization, and operating room contamination from inspired gases. Since 1984, we have developed a technique utilizing jet ventilation delivered through a metal delivery system providing a relatively safe, ignition-free environment. A total intravenous anesthetic technique

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24

Choi, Young Kyoo, Tae Wan Lim, Dae Eon Kim, et al. "Measurement of Hemodynamic Changes Caused by Administration of Atracurium Besylate after Pretreatment with Anti-histamine Agent." Korean Journal of Anesthesiology 52, no. 6 (2007): 642. http://dx.doi.org/10.4097/kjae.2007.52.6.642.

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25

Smith, C. E., M. M. Van Miert, C. J. R. Parker, and J. M. Hunter. "A comparison of the infusion pharmacokinetics and pharmacodynamics of cisatracurium, the 1R‐ cis 1′R‐ cis isomer of atracurium, with atracurium besylate in healthy patients." Anaesthesia 52, no. 9 (1997): 833–41. http://dx.doi.org/10.1111/j.1365-2044.1997.195-az0331.x.

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26

Doğan, Sevil Ceyhan, Zubeyde Akin Polat, Serpil Deren, Saliha Feyza Yayci, and Ali Cetin. "Effects of neuromuscular blocking drugs on viability of human umbilical vein endothelial cells (HUVECs)." Journal of International Medical Research 48, no. 6 (2020): 030006052091088. http://dx.doi.org/10.1177/0300060520910888.

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Objective This study aimed to investigate the effects of neuromuscular blocking drugs on the viability of human umbilical vein endothelial cells (HUVECs) and to investigate whether they cause vascular complications due to cell proliferation. Methods HUVECs were cultivated with 5% CO2 at 37°C in a predefined supplemented medium over 7 days until confluence of cell monolayers. Assays were conducted during the exponential growth phase. Suxamethonium chloride, vecuronium bromide, atracurium besylate, and rocuronium bromide were used at concentrations of 10–5, 10–6, and 10–7 M in proliferation assa

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27

Aguilar, Adrià, Anna Andaluz, Xavier Moll, Carles Cristòfol, and Fèlix García. "Effect of age on cis-atracurium besylate pharmacokinetics following a single 1 mg kg–1 intravenous bolus in young pigs." Veterinary Anaesthesia and Analgesia 46, no. 5 (2019): 643–51. http://dx.doi.org/10.1016/j.vaa.2018.11.012.

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28

Eastwood, N. B., A. H. Boyd, C. J. Parker, and J. M. Hunter. "Pharmacokinetics of 1R-cis 1'R-cis atracurium besylate (51W89) and plasma laudanosine concentrations in health and chronic renal failure." British Journal of Anaesthesia 75, no. 4 (1995): 431–35. http://dx.doi.org/10.1093/bja/75.4.431.

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29

Nehmer, Ulrich. "Simultaneous determination of atracurium besylate and its major decomposition products and related impurities by reversed-phase high-performance liquid chromatography." Journal of Chromatography A 435 (January 1988): 425–33. http://dx.doi.org/10.1016/s0021-9673(01)82207-x.

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30

Меlnyk, S. V. "Dynamics of indices of cerebral oximetry in various procedures of general anesthesia on stages of transduodenal endoscopic operative interventions in patients, suffering obturation jaundice." Klinicheskaia khirurgiia 85, no. 6 (2018): 30–32. http://dx.doi.org/10.26779/2522-1396.2018.06.30.

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Objective. To study the impact of separate anesthesiological procedures on cerebral oxygenation on stages of transduodenal endoscopic operative interventions in patients, suffering obturation jaundice. Маterials and methods. A monitoring investigation for the cerebral oxygenation state was conducted in patients of three investigated groups in conditions of various procedures of general anesthesia. Моnitoring of cerebral oxygenation was done, using the monitoring system, named INVOS 500B. In patients of Group I the intravenous general anesthesia with propofol and fentanyl in conditions of

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31

Vandenbrom, Ron H. G., J. Mark K. H. Wierda, and Sandor Agoston. "Pharmacokinetics and Neuromuscular Blocking Effects of Atracurium Besylate and Two of Its Metabolites in Patients with Normal and Impaired Renal Function." Clinical Pharmacokinetics 19, no. 3 (1990): 230–40. http://dx.doi.org/10.2165/00003088-199019030-00006.

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32

Mistry, Nisha, Andrew D. Roberts, George E. Tranter, et al. "Directly Coupled Chiral HPLC−NMR and HPLC−CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate." Analytical Chemistry 71, no. 14 (1999): 2838–43. http://dx.doi.org/10.1021/ac990132e.

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33

Galluzzi, F., F. De Rensis, R. Saleri, and G. Spattini. "Effect of urethral infusion of atracurium besylate on manual bladder expression in dogs and cats with spinal cord injuries: a randomised trial." Veterinary Record 176, no. 21 (2015): 545. http://dx.doi.org/10.1136/vr.102825.

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34

Nessiem, Marina A., Safa'a M. Riad, Ahmed S. Fayed, and Reham M. Arafa. "Comparative study for chiral separation of Atracurium besylate isomers: Eco-friendly HPLC using Lux Cellulose-3 chiral column, and TLC-Densitomerty approaches." Sustainable Chemistry and Pharmacy 37 (February 2024): 101358. http://dx.doi.org/10.1016/j.scp.2023.101358.

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35

Kumbhare, Nivedika, Anuj Dubey, Chandra Sekhar Mishra, Vinay Yadav, and Nupur Chakravarty. "To Compare Isobaric Thoracic Spinal Anesthesia Versus General Anesthesia in Laparascopy Cholecystectomy." Indian Journal of Anesthesia and Analgesia 10, no. 1 (2023): 15–20. http://dx.doi.org/10.21088/ijaa.2349.8471.10123.2.

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Background: The laparoscopic cholecystectomy procedure is typically carried out under general anesthesia, but regional techniques, such as low thoracic isobaric spinal anesthesia, have been used to manage patients with significant medical problem like coexisting systemic disease, who are deemed to be high risk in general anesthesia. Segmental spinal anesthesia has great outcomes in terms of post-operative discomfort, the need for analgesics, relatively fewer complications, and shorter hospital stays. Thus the aim of this study to avoid and minimize the risk of general anesthesia who does not h

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36

Nehmer, Ulrich. "Separation of cis-cis, cis-trans and trans-trans isomers of (±)-atracurium besylate and cis and trans isomers of its major quaternary decomposition products and related impurity by reversed-phase high-performance liquid chromatography." Journal of Chromatography A 457 (January 1988): 127–35. http://dx.doi.org/10.1016/s0021-9673(01)82060-4.

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37

Dorofeeva, G. S. "Analysis of the effect of dexmedetomidine combination with regional anesthesia on the cognitive state in the post-anesthesia period in ophthalmic surgery." EMERGENCY MEDICINE 17, no. 5 (2022): 74–78. http://dx.doi.org/10.22141/2224-0586.17.5.2021.240710.

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Given a reduced cognitive reserve in patients in ophthalmic surgery, an anesthesiologist should pay special attention when choosing a method of anesthesia to prevent the development of postoperative cognitive dysfunction. The concept of multimodal anesthesia makes it possible to reduce the total number of narcotic analgesics and ataractics used intraoperatively while maintaining an adequate level of anesthesia and sedation, both intraoperatively and in the postoperative period. In ophthalmic surgery, regional anesthesia (pterygopalatine fossa blockade) is used before surgery in combination wit

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38

Sadia, Ishtiaq Adeela Shafiq Aamir Qayyum. "PARAPHENYLENEDIAMINE POISOINING: SCIENTIFIC STEUCTURES AND DIFFICULTIES IN THE TERTIARY CARE INSTITUTION." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 07 (2019): 14183–86. https://doi.org/10.5281/zenodo.3303662.

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<strong><em>Objectives: </em></strong><em>Real post-operatively discomfort regulator remains very important constituent of maintenance</em> <em>Of clinical cases. Numerous painkilling routines were experienced to guarantee passable postoperatively discomfort respite. Researchers led the current research to associate effectiveness of backbone anesthesia against over-all anesthesia concerning post-operatively discomfort subsequent laparoscopic cholecystectomy.</em> <strong><em>Methodology: </em></strong><em>Afterwards the endorsement of Health care center moral board, 130 women remained comprise

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Chabanovych, N. B., M. Yu Mamonova, S. V. Konotopchyk, D. V. Shchehlov, and M. B. Vyval. "Analysis of the experience of anesthetic management during endovascular mechanical thrombectomy in ischemic cerebral stroke." Endovascular Neuroradiology 34, no. 4 (2020): 70–81. http://dx.doi.org/10.26683/2304-9359-2020-4(34)-70-81.

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Objective ‒ to analyze our own experience of anesthetic management during mechanical thrombectomy (MTE) in patients with acute ischemic stroke (AIS) caused by large cerebral vessels occlusion. Materials and methods. Treatment of patients with AIS caused by large cerebral vessels occlusion was carried out in accordance with the recommendations of the European Stroke Organization (ESO). MTE was performed in 63 patients (23 women and 40 men aged 36 to 82 years, mean age ‒ 62.00 ± 16.31 years). The severity of neurological symptoms in the acute period of ischemic stroke was assessed over time usin

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"▾ Atracurium - a novel muscle relaxant." Drug and Therapeutics Bulletin 23, no. 13 (1985): 51–52. http://dx.doi.org/10.1136/dtb.23.13.51.

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Atracurium besylate (Tracrium - Calmic) is a non-depolarising neuromuscular blocking drug of intermediate duration, specifically designed to be degraded spontaneously at physiological pH and temperature.1

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"▾ Vecuronium - another intermediate duration neuromuscular blocking drug." Drug and Therapeutics Bulletin 25, no. 5 (1987): 19–20. http://dx.doi.org/10.1136/dtb.25.5.19.

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Vecuronium bromide (Norcuron - Organon) is a neuromuscular blocking drug introduced in the UK shortly after atracurium besylate. The manufacturer claims it is free from significant unwanted cardiovascular effects, causes minimal histamine release and has low renal elimination and so does not cumulate.

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42

SAHU, ALISHA, SAMBEET SWAIN, SOUMYA SAMAL, and SIBANARAYAN MOHANTY. "EFFICACY OF ATRACURIUM VERSUS CISATRACURIUM IN PATIENTS UNDERGOING RETROGRADE CHOLANGIOPANCREATOGRAPHY PROCEDURE UNDER GENERAL ANAESTHESIA – A COMPARATIVE STUDY." Asian Journal of Pharmaceutical and Clinical Research, April 30, 2020, 197–201. http://dx.doi.org/10.22159/ajpcr.2020.v13i7.37824.

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Objectives: The objectives of the study were to compare the efficacy of injection atracurium 0.5 mg/kg intravenous (IV) versus injection cisatracurium 0.2 mg/kg IV for intubation in patients undergoing endoscopic retrograde cholangiopancreatography procedure (ERCP). Methods: Hundred adult patients of both sexes in the age group of 18–60 years belonging to the American Society of Anesthesiologists I/II category posted for ERCP procedures under general anesthesia were randomly allocated into two groups of 50 each. Group A received injection atracurium besylate 0.5 mg/kg intravenously and G

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Ma'mun, Ahmed, Mohamed K Abd El-Rahman, and Mohamed Abd El-Kawy. "Atracurium Besylate: Chemo-degradable and bio-degradable pharmaceutically active drug." Global Drugs and Therapeutics 3, no. 4 (2018). http://dx.doi.org/10.15761/gdt.1000152.

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44

Oza, Vrinda P., Vandana S. Parmar, Mayur B. Patel, and Feny C. Thakkar. "Efficacy of Cis-Atracurium vs Atracurium in Patients undergoing Abdominal Procedures: A Randomised Clinical Study." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2024. http://dx.doi.org/10.7860/jcdr/2024/68048.19272.

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Introduction: Cis-atracurium has a neuromuscular blocking capacity approximately three times that of atracurium besylate. The Effective Dose (ED) 95 of cis-atracurium is 0.04 mg/kg, while that of atracurium is 0.2 mg/kg. Cis-atracurium is preferred over atracurium due to the lack of histamine release, providing better cardiovascular stability. This study compares these two drugs in terms of haemodynamic parameters, neuromuscular blocking properties, intubating conditions, and safety profiles. Aim: To assess the efficacy of atracurium and cis-atracurium from various perspectives, including neur

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45

Galoria, Darshan, Srushti Shukla, Arijit Datta, et al. "Lethal Self-Administration of Atracurium: A Rarely Reported Case with Review of Literature." American Journal of Forensic Medicine & Pathology, October 4, 2024. http://dx.doi.org/10.1097/paf.0000000000000985.

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Abstract Atracurium besylate is a nondepolarizing skeletal muscle relaxant first introduced in 1980. It is used during endotracheal intubation. It causes muscle relaxation during surgery or mechanical ventilation. When people consider suicide, they employ drugs found in their surroundings but not usually injectable muscle relaxants, which are not widely available. Studies on their use in suicide are rarely reported worldwide. This was a case of a 34-year-old male nursing staff, working in the general surgery department's operation theater complex, who was found unconscious in bed in his room i

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Wei, AY. "Cis-atracurium besylate during induction of general anaesthesia in patients with pneumoconiosis and hepatic insufficiency during simultaneous large-volume lavage of both lungs." JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS 35, no. 5 (2021). https://doi.org/10.23812/21-240-l.

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Letscher, Hélène, Julien Lemaitre, Emma Burban, et al. "An Experimental Study to Optimize Neuromuscular Blockade Protocols in Cynomolgus Macaques: Monitoring, Doses, and Antagonism." Journal of Medical Primatology 53, no. 5 (2024). http://dx.doi.org/10.1111/jmp.12736.

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ABSTRACTBackgroundNeuromuscular blocking agents (NMBAs) are a crucial component of anesthesia and intensive care through the relaxation of skeletal muscles. They can lead to adverse reactions such as postoperative residual neuromuscular block. Only one agent is capable of an instant block reversal in deep block situations, but is restricted to aminosteroid agents. Among animal models, non‐human primates are an essential model for a great diversity of human disease models. The main objective of this study was to establish a model for NMBA monitoring with current available drugs before testing n

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Ndorbor, Theophilus, and Yong Wang. "Chromatographic and Molecular Simulation Study on the Chiral Recognition of Atracurium Besylate Positional Isomers on Cellulose Tri-3, 5 Dimethylphenycarbamate (CDMPC) Column and its Recognition Mechanism." Journal of Chromatography & Separation Techniques 04, no. 03 (2013). http://dx.doi.org/10.4172/2157-7064.1000176.

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Kalmykov, I., I. Kastyro, V. Popadyuk та ін. "Редактирование Вкл. General anesthesia methods and their influence on HRV and pain syndrome after rhinosurgery". Journal of Clinical Physiology and Pathology 1, № 1 (2022). http://dx.doi.org/10.59315/jiscpp.2022-1-1.28-34.

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Aims: to evaluate various methods of anesthesia during septoplasty for changes in heart rate variability (HRV) and acute pain syndrome in the early postoperative period. Patients and methods. All patients received local anesthesia with 2% procaine solution. In group 1(105 people) premedication was used with 2% promedol solution and 60 mg of ketorolac in the evening, in group 2 (108 people) - fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine and metoclopramide, in group 3 (78 people) - atracuria besylate, sodium thiopental, nitrous oxide and halothane. In groups 2 and 3, 100

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Попадюк, В. И., И. В. Кастыро, Ю. Е. Дьяченко, Н. В. Ермакова, А. О. Быкова та В. И. Торшин. "ОСТРЫЙ ПОСТОПЕРАЦИОННЫЙ БОЛЕВОЙ СИНДРОМ У ПАЦИЕНТОВ РИНОХИРУРГИЧЕСКОГО ПРОФИЛЯ ПОСЛЕ ИСПОЛЬЗОВАНИЯ ПОПУЛЯРНЫХ МЕТОДОВ АНЕСТЕЗИИ В Г. МОСКВЕ." Head and neck. Russian Journal 10, № 2 (2022). https://doi.org/10.25792/hn.2022.10.2.s2.58-65.

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Цель исследования: сравнить качество анестезии наиболее часто используемых анестезиологических пособий при септопластике в клиниках Москвы. Пациенты и методы. Всем пациентам применялась местная анестезия 2% раствором прокаина. В 1 группе (55 чел.) использована премедикация 2% раствором промедола, во 2 группе (53 чел.) – фентанил, пропофол, цисатракурия безилат, транексамовую кислоту, атропин и метоклопрамид, в 3 группе (56 чел.) – атракурия безилат, тиопентал натрия, закись азота и галотан. Во всех группах вечером в день операции внутримышечно использовали 100 мг кетопрофена однократно. Передн

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