Log in

Relevant bibliographies by topics / Atrial differentiation / Journal articles

To see the other types of publications on this topic, follow the link: Atrial differentiation.

Journal articles on the topic 'Atrial differentiation'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Atrial differentiation.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Mesquita, Fernanda C. P., Jacquelynn Morrissey, Po-Feng Lee, et al. "Cues from human atrial extracellular matrix enrich the atrial differentiation of human induced pluripotent stem cell-derived cardiomyocytes." Biomaterials Science 9, no. 10 (2021): 3737–49. http://dx.doi.org/10.1039/d0bm01686a.

Full text

Abstract:

Decellularized extracellular matrix (dECM) from human atria preserves key native components that directed the cardiac differentiation of hiPSCs to an atrial-like phenotype, yielding a twofold increase of functional atrial-like cells.

APA, Harvard, Vancouver, ISO, and other styles

2

Rautaharju, Pentti M. "Differentiation of atrial flutter from atrial fibrillation." Journal of Electrocardiology 33, no. 2 (2000): 203. http://dx.doi.org/10.1016/s0022-0736(00)80078-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Davies, M. J., J. Rode, N. Woolf, and D. M. Krikler. "NEUROENDOCRINE DIFFERENTIATION IN ATRIAL MYXOMAS." Lancet 330, no. 8562 (1987): 800. http://dx.doi.org/10.1016/s0140-6736(87)92533-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Knight, Bradley P., Gregory F. Michaud, S. Adam Strickberger, and Fred Morady. "Electrocardiographic differentiation of atrial flutter from atrial fibrillation by physicians." Journal of Electrocardiology 32, no. 4 (1999): 315–19. http://dx.doi.org/10.1016/s0022-0736(99)90002-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Muir, T. M., J. Hair, G. C. Inglis, J. W. Dow, G. B. Lindop, and B. J. Leckie. "Dexamethasone-induced differentiation of atrial myocytes in culture." American Journal of Physiology-Heart and Circulatory Physiology 263, no. 3 (1992): H722—H729. http://dx.doi.org/10.1152/ajpheart.1992.263.3.h722.

Full text

Abstract:

Atrial and ventricular myocytes from fetal and newborn rats were cultured in medium supplemented with fetal or newborn calf serum with and without glucocorticoid. Myocyte morphology was examined by light and electron microscopy, and the amount of stored and secreted atrial natriuretic peptide (ANP) was measured. Without dexamethasone, neonatal atrial myocytes cultured for 7 days contained myofibrils organized into sarcomeres and numerous endocrine granules containing immunostainable ANP. Secretion of immunoreactive ANP reached a peak between days 7 and 9 of culture. Myocytes from fetal rats se

APA, Harvard, Vancouver, ISO, and other styles

6

Schwach, Verena, Carla Cofiño-Fabres, Simone A. ten Den та Robert Passier. "Improved Atrial Differentiation of Human Pluripotent Stem Cells by Activation of Retinoic Acid Receptor Alpha (RARα)". Journal of Personalized Medicine 12, № 4 (2022): 628. http://dx.doi.org/10.3390/jpm12040628.

Full text

Abstract:

Human pluripotent stem cell (hPSC)-derived cardiomyocytes have proven valuable for modeling disease and as a drug screening platform. Here, we depict an optimized protocol for the directed differentiation of hPSCs toward cardiomyocytes with an atrial identity by modulating the retinoic acid signaling cascade in spin embryoid bodies. The crucial steps of the protocol, including hPSC maintenance, embryoid body (EB) differentiation, the induction of cardiac mesoderm, direction toward the atrial phenotype, as well as molecular and functional characterization of the cardiomyocytes, are described. A

APA, Harvard, Vancouver, ISO, and other styles

7

Yao, Yao, Amanda N. Marra, and Deborah Yelon. "Pathways Regulating Establishment and Maintenance of Cardiac Chamber Identity in Zebrafish." Journal of Cardiovascular Development and Disease 8, no. 2 (2021): 13. http://dx.doi.org/10.3390/jcdd8020013.

Full text

Abstract:

The vertebrate heart is comprised of two types of chambers—ventricles and atria—that have unique morphological and physiological properties. Effective cardiac function depends upon the distinct characteristics of ventricular and atrial cardiomyocytes, raising interest in the genetic pathways that regulate chamber-specific traits. Chamber identity seems to be specified in the early embryo by signals that establish ventricular and atrial progenitor populations and trigger distinct differentiation pathways. Intriguingly, chamber-specific features appear to require active reinforcement, even after

APA, Harvard, Vancouver, ISO, and other styles

8

Wolke, Carmen, Elmer Antileo, and Uwe Lendeckel. "WNT signaling in atrial fibrillation." Experimental Biology and Medicine 246, no. 9 (2021): 1112–20. http://dx.doi.org/10.1177/1535370221994086.

Full text

Abstract:

The Wnt signaling pathway regulates physiological processes such as cell proliferation and differentiation, cell fate decisions, and stem cell maintenance and, thus, plays essential roles in embryonic development, but also in adult tissue homeostasis and repair. The Wnt signaling pathway has been associated with heart development and repair and has been shown to be crucially involved in proliferation and differentiation of progenitor cells into cardiomyocytes. The investigation of the role of the Wnt signaling pathway and the regulation of its expression/activity in atrial fibrillation has onl

APA, Harvard, Vancouver, ISO, and other styles

9

Hotchkiss, Adam, Tiam Feridooni, Mark Baguma-Nibasheka, Kathleen McNeil, Sarita Chinni, and Kishore B. S. Pasumarthi. "Atrial natriuretic peptide inhibits cell cycle activity of embryonic cardiac progenitor cells via its NPRA receptor signaling axis." American Journal of Physiology-Cell Physiology 308, no. 7 (2015): C557—C569. http://dx.doi.org/10.1152/ajpcell.00323.2014.

Full text

Abstract:

The biological effects of atrial natriuretic peptide (ANP) are mediated by natriuretic peptide receptors (NPRs), which can either activate guanylyl cyclase (NPRA and NPRB) or inhibit adenylyl cyclase (NPRC) to modulate intracellular cGMP or cAMP, respectively. During cardiac development, ANP serves as an early maker of differentiating atrial and ventricular chamber myocardium. As development proceeds, expression of ANP persists in the atria but declines in the ventricles. Currently, it is not known whether ANP is secreted or the ANP-NPR signaling system plays any active role in the developing

APA, Harvard, Vancouver, ISO, and other styles

10

Suffee, Nadine, Thomas Moore-Morris, Patrick Farahmand, et al. "Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria." Proceedings of the National Academy of Sciences 114, no. 5 (2017): E771—E780. http://dx.doi.org/10.1073/pnas.1610968114.

Full text

Abstract:

The abundance of epicardial adipose tissue (EAT) is associated with atrial fibrillation (AF), the most frequent cardiac arrhythmia. However, both the origin and the factors involved in EAT expansion are unknown. Here, we found that adult human atrial epicardial cells were highly adipogenic through an epithelial–mesenchymal transition both in vitro and in vivo. In a genetic lineage tracing the WT1CreERT2+/−RosatdT+/−mouse model subjected to a high-fat diet, adipocytes of atrial EAT derived from a subset of epicardial progenitors. Atrial myocardium secretome induces the adipogenic differentiatio

APA, Harvard, Vancouver, ISO, and other styles

11

Kallstrom, Eric, Elizabeth Kallus, Krista Erbe, Michael Rampoldi, Don Le, and Neeley Bryan. "Differentiation of Left Atrial Myxomas by Multimodality Imaging." Journal of Diagnostic Medical Sonography 36, no. 1 (2019): 52–63. http://dx.doi.org/10.1177/8756479319872153.

Full text

Abstract:

A tumor is an excessive growth of cells that results from the body’s inability to balance the growth of new cells and the destruction of old cells. Tumors can occur throughout the body and are classified as either benign or malignant. However, cardiac tumors are a rare occurrence. When present, several imaging modalities are available to illustrate their presence and characteristics. Not all cardiac masses look similar and, depending on their size and location, may pose different health risks to the patient. This case series introduces six left atrial myxomas with dissimilar appearances initia

APA, Harvard, Vancouver, ISO, and other styles

12

Chen, Tangting, Miaoling Li, Xuehui Fan, Jun Cheng, and Liqun Wang. "Sodium Tanshinone IIA Sulfonate Prevents Angiotensin II-Induced Differentiation of Human Atrial Fibroblasts into Myofibroblasts." Oxidative Medicine and Cellular Longevity 2018 (July 24, 2018): 1–10. http://dx.doi.org/10.1155/2018/6712585.

Full text

Abstract:

Differentiation of atrial fibroblasts into myofibroblasts plays a critical role in atrial fibrosis. Sodium tanshinone IIA sulfonate (DS-201), a water-soluble derivative of tanshinone IIA, has been shown to have potent antifibrotic properties. However, the protective effects of DS-201 on angiotensin II- (Ang II-) induced differentiation of atrial fibroblasts into myofibroblasts remain to be elucidated. In this study, human atrial fibroblasts were stimulated with Ang II in the presence or absence of DS-201. Then, α-smooth muscle actin (α-SMA), collagen I, and collagen III expression and reactive

APA, Harvard, Vancouver, ISO, and other styles

13

Chang, Wei-Ting, Jhih-Yuan Shih, Yu-Wen Lin, Zhih-Cherng Chen, Jun-Neng Roan, and Chih-Hsin Hsu. "Growth differentiation factor-15 levels in the blood around the pulmonary artery is associated with hospitalization for heart failure in patients with pulmonary arterial hypertension." Pulmonary Circulation 10, no. 4 (2020): 204589402096294. http://dx.doi.org/10.1177/2045894020962948.

Full text

Abstract:

Despite no significant differences of growth differentiation factor-15 expressions in peripheral, right atrial, and right ventricular blood, in the pulmonary arterial blood, there was a significantly high level of growth differentiation factor-15 in Group I pulmonary arterial hypertension patients subsequently developing heart failure. During right heart catheterization, collecting pulmonary blood samples is suggested to measure growth differentiation factor-15.

APA, Harvard, Vancouver, ISO, and other styles

14

Song, Xianghe, Danni Liu, Jian Cui, et al. "Identification of Stem-Like Cells in Atrial Myxoma by Markers CD44, CD19, and CD45." Stem Cells International 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/2059584.

Full text

Abstract:

Atrial myxoma is the most frequent tumor arising mainly in atrial septum and its origin remains uncertain. It has been reported that a subpopulation of stem-like cells are present in benign tumors and responsible for tumor initiation and maintenance. In this study, we investigated whether stem-like cells could contribute to the atrial cardiac myxoma. Immunohistology data confirmed that a population of cells bearing the surface markers CD19, CD45, and CD44 resided in a mucopolysaccharide-rich matrix of myxoma. Moreover, we isolated myxoma cells with phase-bright culture method and confirmed tha

APA, Harvard, Vancouver, ISO, and other styles

15

Balabanovich, T. I., V. I. Shyshko, and V. R. Shulika. "CIRCULATING SERUM LEVELS OF GROWTH DIFFERENTIATION FACTOR-15 IN NON-VALVULAR ATRIAL FIBRILLATION PATIENTS WITH CONCOMITANT OBSTRUCTIVE SLEEP APNEA/HYPOPNEA SYNDROME." Biological Markers in Fundamental and Clinical Medicine (collection of abstracts) 2, no. 2 (2018): 35–36. http://dx.doi.org/10.29256/v.02.02.2018.escbm27.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Sutton, Kathy, Said El Haou, Sarah Williams, et al. "Differentiation and validation of human iPSC-derived atrial cardiomyocytes." Journal of Pharmacological and Toxicological Methods 93 (September 2018): 168. http://dx.doi.org/10.1016/j.vascn.2018.01.544.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Kornej, Jelena, Samira Zeynalova, Petra Büttner, et al. "Differentiation of atrial fibrillation progression phenotypes using Troponin T." International Journal of Cardiology 297 (December 2019): 61–65. http://dx.doi.org/10.1016/j.ijcard.2019.09.006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Rajala, Kristiina, Mari Pekkanen-Mattila, and Katriina Aalto-Setälä. "Cardiac Differentiation of Pluripotent Stem Cells." Stem Cells International 2011 (2011): 1–12. http://dx.doi.org/10.4061/2011/383709.

Full text

Abstract:

The ability of human pluripotent stem cells to differentiate towards the cardiac lineage has attracted significant interest, initially with a strong focus on regenerative medicine. The ultimate goal to repair the heart by cardiomyocyte replacement has, however, proven challenging. Human cardiac differentiation has been difficult to control, but methods are improving, and the process, to a certain extent, can be manipulated and directed. The stem cell-derived cardiomyocytes described to date exhibit rather immature functional and structural characteristics compared to adult cardiomyocytes. Thus

APA, Harvard, Vancouver, ISO, and other styles

19

Hu, Xiao Feng, Rui Zhan, Shanhu Xu, et al. "Growth differentiation factor 15 is associated with left atrial/left atrial appendage thrombus in patients with nonvalvular atrial fibrillation." Clinical Cardiology 41, no. 1 (2018): 34–38. http://dx.doi.org/10.1002/clc.22844.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Kohtz, D. S., N. R. Dische, T. Inagami, and B. Goldman. "Growth and partial differentiation of presumptive human cardiac myoblasts in culture." Journal of Cell Biology 108, no. 3 (1989): 1067–78. http://dx.doi.org/10.1083/jcb.108.3.1067.

Full text

Abstract:

A cell culture model for human cardiac myogenesis is introduced. Human fetal myocardial cells were dissociated enzymatically, and cultured in a mitogen-rich medium that promoted the growth of presumptive cardiac myoblasts. Strains of human cardiac myoblasts were generated from different anatomical regions of the fetal heart. The cells could be cultured for at least 30 generations, or frozen and recovered for later use. Differentiation was induced by culturing the cardiac myoblasts in a mitogen-poor medium. Differentiation of cardiac myoblasts was marked primarily by transcriptional activation

APA, Harvard, Vancouver, ISO, and other styles

21

Sarraf, Lara S., James A. Roth, and Kristina M. Ropella. "Differentiation of atrial rhythms from the electrocardiogram with coherence spectra." Journal of Electrocardiology 35, no. 1 (2002): 59–67. http://dx.doi.org/10.1054/jelc.2002.29944.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

SATIN, J., D. BADER, and R. DEHAAN. "Local cues influence atrial and ventricular differentiation of precardiac mesoderm." Journal of Molecular and Cellular Cardiology 19 (1987): S16. http://dx.doi.org/10.1016/s0022-2828(87)80673-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Bhatia, Snigdha, Amna Qasim, Amyn K. Jiwani, and Ashraf M. Aly. "Benign Structures Mimicking Right Atrial Masses on Prenatal Ultrasound." Case Reports in Pediatrics 2021 (January 12, 2021): 1–4. http://dx.doi.org/10.1155/2021/8889941.

Full text

Abstract:

Advances in imaging have resulted in more frequent reporting of primitive right atrial structures which can sometimes mimic cardiac tumors in prenatal ultrasound. Prominent crista terminalis and Chiari network are examples of these structures. We describe two cases of pregnant women referred to the fetal cardiology clinic for fetal echocardiography for right atrial masses seen on prenatal ultrasound suspicious of tuberous sclerosis. The first case subsequently diagnosed as crista terminalis and the second case as a prominent Chiari network. Postnatal ECHO confirmed the benign nature of these s

APA, Harvard, Vancouver, ISO, and other styles

24

Coppola, Ugo, Bitan Saha, Jennifer Kenney, and Joshua S. Waxman. "A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish." PLOS Genetics 20, no. 11 (2024): e1011222. http://dx.doi.org/10.1371/journal.pgen.1011222.

Full text

Abstract:

Nr2f transcription factors (TFs) are conserved regulators of vertebrate atrial cardiomyocyte (AC) differentiation. However, little is known about the mechanisms directing Nr2f expression in ACs. Here, we identified a conserved enhancer 3’ to the nr2f1a locus, which we call 3’reg1-nr2f1a (3’reg1), that can promote Nr2f1a expression in ACs. Sequence analysis of the enhancer identified putative Lef/Tcf and Foxf TF binding sites. Mutation of the Lef/Tcf sites within the 3’reg1 reporter, knockdown of Tcf7l1a, and manipulation of canonical Wnt signaling support that Tcf7l1a is derepressed via Wnt si

APA, Harvard, Vancouver, ISO, and other styles

25

Willems, Leen, Annick Daniëls, Yanick Fanton, et al. "Differentiation of Human Cardiac Atrial Appendage Stem Cells into Adult Cardiomyocytes: A Role for the Wnt Pathway?" International Journal of Molecular Sciences 21, no. 11 (2020): 3931. http://dx.doi.org/10.3390/ijms21113931.

Full text

Abstract:

Human cardiac stem cells isolated from atrial appendages based on aldehyde dehydrogenase activity (CASCs) can be expanded in vitro and differentiate into mature cardiomyocytes. In this study, we assess whether Wnt activation stimulates human CASC proliferation, whereas Wnt inhibition induces cardiac maturation. CASCs were cultured as described before. Conventional PCR confirmed the presence of the Frizzled receptors. Small-molecule inhibitors (IWP2, C59, XAV939, and IWR1-endo) and activator (CHIR99021) of the Wnt/β -catenin signaling pathway were applied, and the effect on β-catenin and target

APA, Harvard, Vancouver, ISO, and other styles

26

Eckstein, Jan, Vanessa Sciacca, Hermann Körperich, et al. "Cardiovascular Magnetic Resonance Imaging-Based Right Atrial Strain Analysis of Cardiac Amyloidosis." Biomedicines 10, no. 12 (2022): 3004. http://dx.doi.org/10.3390/biomedicines10123004.

Full text

Abstract:

Background: Cardiac amyloidosis (CA) manifests in a hypertrophic phenotype with a poor prognosis, making differentiation from hypertrophic cardiomyopathy (HCM) challenging and delaying early treatment. The extent to which magnetic resonance imaging (MRI) quantifies the right atrial strain (RAS) and strain rate (RASR), providing valuable diagnostic information, is not yet clinically established. Aims: This study assesses diagnostic differences in the longitudinal RAS and RASR between CA and HCM patients, control subjects (CTRL) and CA subtypes in addition to the impact of atrial fibrillation (A

APA, Harvard, Vancouver, ISO, and other styles

27

Zhang, Y., S. A. Shafiq, and D. Bader. "Detection of a ventricular-specific myosin heavy chain in adult and developing chicken heart." Journal of Cell Biology 102, no. 4 (1986): 1480–84. http://dx.doi.org/10.1083/jcb.102.4.1480.

Full text

Abstract:

In the present study, a monoclonal antibody (McAb), ALD19, generated against myosin of slow tonic muscle, was shown to react with the heavy chain of ventricular myosin in the adult chicken heart. With this antibody, it was possible to detect a ventricular-specific myosin during myocardial differentiation and to show that the epitope recognized by ALD19 was present from the earliest stages of ventricular differentiation and maintained throughout development only in the ventricle. A second McAb, specific for atrial myosin heavy chain (MHC) (Gonzalez-Sanchez, A., and D. Bader, 1984, Dev. Biol., 1

APA, Harvard, Vancouver, ISO, and other styles

28

Malakhov, A. I., S. I. Schookin, V. I. Ivancov, and A. N. Tikhomirov. "A Combined Algorithm for Identification and Differentiation of Atrial Flutter and Atrial Fibrillation Based on ECG Analysis." Biomedical Engineering 47, no. 1 (2013): 14–17. http://dx.doi.org/10.1007/s10527-013-9324-y.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Torre, Eleonora, Matteo E. Mangoni, Alain Lacampagne, Albano C. Meli, and Pietro Mesirca. "State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells." International Journal of Molecular Sciences 25, no. 6 (2024): 3387. http://dx.doi.org/10.3390/ijms25063387.

Full text

Abstract:

Human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes raise the possibility of generating pluripotent stem cells from a wide range of human diseases. In the cardiology field, hiPSCs have been used to address the mechanistic bases of primary arrhythmias and in investigations of drug safety. These studies have been focused primarily on atrial and ventricular pathologies. Consequently, many hiPSC-based cardiac differentiation protocols have been developed to differentiate between atrial- or ventricular-like cardiomyocytes. Few protocols have successfully proposed ways to obtain hiPSC

APA, Harvard, Vancouver, ISO, and other styles

30

SEÇİNTİ, İlke Evrim, Didar GÜRSOY, Metin Onur BEYAZ, and İyad FANSA. "Undifferentiated pleomorphic sarcoma with focal myogenic differentiation mimicking left atrial myxoma." Journal of Surgery and Medicine 6, no. 4 (2022): 1. http://dx.doi.org/10.28982/josam.992197.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Kleinsorge, Mandy, and Lukas Cyganek. "Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes." STAR Protocols 1, no. 1 (2020): 100026. http://dx.doi.org/10.1016/j.xpro.2020.100026.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Lin, Huili, Jingsheng Zheng, Kenneth Khaw, et al. "Right Atrial Cardiac Varix Mimicking Myxoma: Differentiation Using Three-Dimensional Echocardiography." Annals of Thoracic Surgery 97, no. 6 (2014): e181. http://dx.doi.org/10.1016/j.athoracsur.2014.02.086.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Park, Jeong-Wook, Yeong-Woong Ha, Sung-Hwan Kim, and Yong-Seog Oh. "Diagnostic utility of atrial entrainment for differentiation of long RP tachycardia." Heart Rhythm 17, no. 9 (2020): 1629–31. http://dx.doi.org/10.1016/j.hrthm.2020.04.025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Vugt, Stijn Van, Goaris Aarts, Jeroen Jaspers Focks, Lucie Bloem, Freek Verheugt, and Marc Brouwer. "NOVEL APPROACH FOR RISK DIFFERENTIATION IN ATRIAL FIBRILLATION PATIENTS WITH POLYPHARMACY." Journal of the American College of Cardiology 69, no. 11 (2017): 486. http://dx.doi.org/10.1016/s0735-1097(17)33875-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

AL-HAMDI, AMAR Talib. "Artifacts in electrocardiogram interpreted as cardiac arrhythmias: Reports of clinical cases." Journal of the Faculty of Medicine Baghdad 62, no. 4 (2021): 104–9. http://dx.doi.org/10.32007/jfacmedbagdad.6241767.

Full text

Abstract:

Background: Artifact waves in the ECG and Holter recording are not rare in clinical practice and can be mistaken for tachyarrhythmia. Objective: To orient the practicing physicians to differentiate these artifacts from cardiac arrhythmias. Patients and Methods: Thirteen patients with incorrectly diagnosed cardiac arrhythmias by ECG or Holter recording then distinguished to be ECG artifacts were included in this study. The patients were collected from the author’s private practice in the northern Iraqi governorate of Sulaimanya during the period from June 2015 to August 2020. The di

APA, Harvard, Vancouver, ISO, and other styles

36

Рождественский, Mikhail Rozhdestvenskiy, Юргель, and E. Yurgel. "Proinflammatory potential for quantitative differentiation of various forms of atrial fibrillation in hypertensive patients in the medico-social examination of disability." Journal of New Medical Technologies. eJournal 9, no. 2 (2015): 0. http://dx.doi.org/10.12737/11522.

Full text

Abstract:

In this article the authors examine changes in the levels of tumor necrosis factor alpha and nitric oxide in the blood in patients with atrial fibrillation and hypertension. The study included 66 patients aged 60 to 75 years compared with the control group of 25 people. The results suggest that endothelial dysfunction is developed in patients. It is manifested by changes in the levels of tumor necrosis factor alpha and nitric oxide in the blood. The studied parameters can be the markers of severity and indicate a differentiated approach to various forms of atrial fibrillation. On the severity,

APA, Harvard, Vancouver, ISO, and other styles

37

Gizatulina, T. P., N. Yu Khorkova, L. U. Martyanova, et al. "The level of growth differentiation factor 15 as a predictor of left atrial thrombosis in patients with nonvalvular atrial fibrillation." Kardiologiia 61, no. 7 (2021): 44–54. http://dx.doi.org/10.18087/cardio.2021.7.n1588.

Full text

Abstract:

Aim To study the role of blood concentration of growth differentiation factor 15 (GDF-15) as a predictor of left atrial/left atrial appendage (LA/LAA) thrombosis in patients with nonvalvular atrial fibrillation (AF).Material and methods 538 patients with nonvalvular AF were admitted to the Tyumen Cardiology Research Center in 2019–2020 for radiofrequency ablation and elective cardioversion. According to findings of transesophageal echocardiography (EcoCG), 42 (7.8%) of these patients had LA/LAA thrombosis and 79 (14.7%) of them had the effect of spontaneous echo contrast (SEC). This comparativ

APA, Harvard, Vancouver, ISO, and other styles

38

Liu, Yang, Haichen Lv, Ruopeng Tan та ін. "Platelets Promote Ang II (Angiotensin II)-Induced Atrial Fibrillation by Releasing TGF-β1 (Transforming Growth Factor-β1) and Interacting With Fibroblasts". Hypertension 76, № 6 (2020): 1856–67. http://dx.doi.org/10.1161/hypertensionaha.120.15016.

Full text

Abstract:

Hypertension is a risk factor of atrial fibrillation (AF), and a certain number of patients with hypertension were found with an enlarged left atrium. Platelet activation is found in patients with hypertension or pressure overload/Ang II (angiotensin II)-induced hypertensive animal models and contribute to ventricular fibrosis. Whether hypertension-induced atrial fibrosis is mediated by platelets remains unknown. Our previous experimental data showed that platelet-derived TGF-β1 (transforming growth factor-β1) was reduced in patients with hypertensive AF. The present study is to investigate wh

APA, Harvard, Vancouver, ISO, and other styles

39

Amin, Mohamed, Yoshihiro Kushida, Shohei Wakao, Masaaki Kitada, Kazuki Tatsumi, and Mari Dezawa. "Cardiotrophic Growth Factor–Driven Induction of Human Muse Cells Into Cardiomyocyte-Like Phenotype." Cell Transplantation 27, no. 2 (2018): 285–98. http://dx.doi.org/10.1177/0963689717721514.

Full text

Abstract:

Multilineage-differentiating stress-enduring (Muse) cells are endogenous nontumorigenic stem cells collectable as stage-specific embryonic antigen 3 (SSEA-3) + from various organs including the bone marrow and are pluripotent-like. The potential of human bone marrow-derived Muse cells to commit to cardiac lineage cells was evaluated. We found that (1) initial treatment of Muse cells with 5′-azacytidine in suspension culture successfully accelerated demethylation of cardiac marker Nkx2.5 promoter; (2) then transferring the cells onto adherent culture and treatment with early cardiac differentia

APA, Harvard, Vancouver, ISO, and other styles

40

Chlumský, J., and J. Charvát. "Contribution of Distensibility and Intima-Media Thickness to the Etiology of Stroke." Rivista di Neuroradiologia 18, no. 1 (2005): 78–81. http://dx.doi.org/10.1177/197140090501800113.

Full text

Abstract:

We evaluated carotid artery distensibility (D) and intima-media thickness (IMT) in patients with stroke (S), and its relationship to diabetes and atrial fibrilation. We measured D and IMT in 89 stroke patients. 59 patients had type II diabetes and 64 patients had atrial fibrillation. D was determined using the Reneman formula (mm/100mm Hg). D was consistently lower in diabetic patients then in non-diabetic patients (0.14 v. 0.17, p=0.039) and showed a relation to IMT. In atrial fibrillation patients IMT was consistently lower (67 v.79 mm, p=0.033) and D was increased (0.19 v. 0.10, p=0.023). T

APA, Harvard, Vancouver, ISO, and other styles

41

Vogel, Britta, Dierk Thomas, Derliz Mereles, Wolfgang Rottbauer, and Hugo A. Katus. "Systemic Embolization and Myocardial Infarction due to Clinically Unrecognized Left Atrial Myxoma." Case Reports in Medicine 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/159024.

Full text

Abstract:

Myxomas are the most common primary tumors of the heart. We report an extraordinary severe case of left atrial myxoma, presenting with stroke, myocardial infarction, and multiple arterial embolism including aorta, splenic and renal arteries, and several peripheral arteries. The patient had previously been diagnosed with systemic vasculitis, a typical but less common finding caused by multiple emboli mimicking vasculitis. The myxoma was removed and atrial septum reconstruction was performed. In summary, early diagnostic differentiation of myxoma from vasculitis is critical, and immediate surgic

APA, Harvard, Vancouver, ISO, and other styles

42

Sciacca, Vanessa, Jan Eckstein, Hermann Körperich, et al. "Magnetic-Resonance-Imaging-Based Left Atrial Strain and Left Atrial Strain Rate as Diagnostic Parameters in Cardiac Amyloidosis." Journal of Clinical Medicine 11, no. 11 (2022): 3150. http://dx.doi.org/10.3390/jcm11113150.

Full text

Abstract:

Aims: The present study aims to evaluate magnetic-resonance-imaging (MRI)-assessed left atrial strain (LAS) and left atrial strain rate (LASR) as potential parameters for the diagnosis of cardiac amyloidosis (CA), the distinction of clinical subtypes and differentiation from other cardiomyopathies. Methods and results: LAS and LASR were assessed by MRI feature tracking in patients with biopsy-proven CA. LAS and LASR of patients with CA were compared to healthy subjects and patients with hypertrophic cardiomyopathy. LAS and LASR were also analyzed concerning differences between patients with tr

APA, Harvard, Vancouver, ISO, and other styles

43

Shi, Tonghuan, Guangji Wang, Jianye Peng та Manhua Chen. "Loss of MD1 Promotes Inflammatory and Apoptotic Atrial Remodelling in Diabetic Cardiomyopathy by Activating the TLR4/NF-κB Signalling Pathway". Pharmacology 108, № 4 (2023): 311–19. http://dx.doi.org/10.1159/000530081.

Full text

Abstract:

<b><i>Introduction:</i></b> Myeloid differentiation protein 1 (MD1), a negative regulator of toll-like receptor 4 (TLR4), is widely expressed in the heart. Recent studies have shown that MD1 plays an important role in cardiac remodelling. However, the effects and potential mechanisms underlying MD1-mediated atrial remodelling in diabetic cardiomyopathy (DCM) remain unclear. Therefore, this study was designed to explore the role of MD1 in DCM-related atrial remodelling. <b><i>Methods:</i></b> MD1 knockout (MD1-KO) mice and wild-type (WT) littermat

APA, Harvard, Vancouver, ISO, and other styles

44

Thorpe, Jordan, Matthew D. Perry, Osvaldo Contreras, et al. "Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia." Stem Cell Research & Therapy 14, no. 1 (2023). http://dx.doi.org/10.1186/s13287-023-03405-5.

Full text

Abstract:

Abstract Background Atrial fibrillation is the most common arrhythmia syndrome and causes significant morbidity and mortality. Current therapeutics, however, have limited efficacy. Notably, many therapeutics shown to be efficacious in animal models have not proved effective in humans. Thus, there is a need for a drug screening platform based on human tissue. The aim of this study was to develop a robust protocol for generating atrial cardiomyocytes from human-induced pluripotent stem cells. Methods A novel protocol for atrial differentiation, with optimized timing of retinoic acid during mesod

APA, Harvard, Vancouver, ISO, and other styles

45

Van Gorp, P. R. R., J. Liu, S. O. Dekker, et al. "P5725Identification of novel cardiomyogenic factors by transcriptome analysis of conditionally immortalized atrial myocytes." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz746.0665.

Full text

Abstract:

Abstract Background Cardiac development involves the properly timed expression of cardiomyogenic differentiation factors (CDFs). CDFs have mainly been discovered using animal models and, more recently, pluripotent stem cell-derived cardiomyocytes (PSC-CMCs). These models are, however, laborious, time-consuming and costly. Also, cardiomyogenic differentiation of CMCs is heterogeneous and yields phenotypically immature CMCs. Recently, our research group generated a monoclonal line of conditionally immortalized atrial myocytes, called iAM-1. After removal of the proliferation stimulus these cells

APA, Harvard, Vancouver, ISO, and other styles

46

Suffee-Mosbah, N., T. Moore-Morris, N. Mougeneot, G. Dilanian, M. Puceat, and S. N. Hatem. "P1232A subpopulation of epicardium-derived cells are preprogrammed towards fibroblast differentiation in the atrial myocardium." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0190.

Full text

Abstract:

Abstract Context and objectives Fibro-fatty infiltrations of the sub-epicardium is an important component of the atrial cardiomyopathy that paves the way of atrial fibrillation (AF). We previously reported that epicardium-derived cells (EPDCs) can be a source of adipocytes contributing to fat depot. Here, we examined if EPDCs can contribute also to the fibrotic remodeling of atrial subepicardium. Methods Surgical samples of human right atria were used for histological study and to harvest EPDCs. Clinical and histological data were analyzed using generalized linear models. A model atrial remode

APA, Harvard, Vancouver, ISO, and other styles

47

Arbault-Biton, Chloé, Camille Chenevier-Gobeaux, Damien Legallois, et al. "Multiple biomarkers measurement to estimate the duration of atrial fibrillation." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, November 27, 2020, 000456322097517. http://dx.doi.org/10.1177/0004563220975171.

Full text

Abstract:

Background An accurate estimation of the duration of atrial fibrillation is critical for its safe management. Recent studies suggested that copeptin, carbohydrate antigen-125, galectin-3 and growth differentiation factor-15 are increased in atrial fibrillation. We examined the ability of these markers to identify patients presenting with atrial fibrillation of ≤48 versus >48 h duration. Methods Retrospective analysis of a prospective study that included patients with atrial fibrillation of known duration. Results A total of 98 patients were analysed, 47 with atrial fibrillation ≤48 h and 51

APA, Harvard, Vancouver, ISO, and other styles

48

Rapöhn, Marcel, Lukas Cyganek, Niels Voigt, Gerd Hasenfuß, Stephan E. Lehnart, and Jörg W. Wegener. "Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM." American Journal of Physiology-Heart and Circulatory Physiology, January 5, 2024. http://dx.doi.org/10.1152/ajpheart.00527.2023.

Full text

Abstract:

Patient-derived induced pluripotent stem cells (iPSC) can be differentiated into atrial and ventricular cardiomyocytes to allow for personalized drug screening. A hallmark of differentiation is the manifestation of spontaneous beating in a 2D cell culture. However, an outstanding observation is the high variability in this maturation process. We valued that contractile parameters change during differentiation serving as an indicator of maturation. Consequently, we recorded non-invasively spontaneous motion activity during differentiation of male iPSC towards iPSC-cardiomyocytes (iPSC-CM) to fu

APA, Harvard, Vancouver, ISO, and other styles

49

Yan, Jingbo, Jianyong Hu, Iris I. Mueller, et al. "Abstract 1964: Bone Morphogenetic Protein Antagonist “Protein Related to Dan and Cerberus” Promotes Differentiation of Embryonic Stem Cells to Atrial Cardiomyocytes." Circulation 118, suppl_18 (2008). http://dx.doi.org/10.1161/circ.118.suppl_18.s_413-a.

Full text

Abstract:

The molecular factors that regulate cardiac differentiation have been extensively studied, yet, relatively little is known about how cardiomyocytes acquire atrial versus ventricular characteristics. Embryonic stem (ES) cells, which have the potential to differentiate to a wide array of distinct cell types, including most types of cardiovascular cells, offer a pertinent in vitro model to work out the molecular mechanisms of atrial specification and differentiation. We discovered that the secreted antagonist of BMP signaling, Protein Related to Dan and Cerberus (PRDC, also called Gremlin2) leads

APA, Harvard, Vancouver, ISO, and other styles

50

Mesquita, Fernanda, Jacquelynn Morrissey, Yutao Xi, et al. "Abstract 281: Human Atrial Extracellular Matrix Drives Differentiation of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Toward an Atrial Phenotype." Circulation Research 127, Suppl_1 (2020). http://dx.doi.org/10.1161/res.127.suppl_1.281.

Full text

Abstract:

Extracellular matrix (ECM) can directly modulate cell proliferation, migration and differentiation by mediating diverse growth factors and signaling interactions. Protocols for cardiomyocyte differentiation of induced pluripotent stem cells (iPSCs) that recapitulate cardiac development frequently result in a mixed cardiac cell population dominated overwhelmingly by ventricular-like cells. Utilizing the inherent biological capabilities of decellularized ECM (dECM) from human myocardium, we developed a method for committing human iPSCs to an atrial-like cell phenotype. We employed a modified dec

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!