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Dissertations / Theses on the topic 'Atrial fibrillation'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Donate, Puertas Rosa. "Omic approach to atrial fibrillation." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1164.

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La fibrillation atriale (FA) est un problème de santé publique majeur dans le monde entier. Le remodelage électrique, structurel et neuronal est sous-jacent à la myopathie atriale. La pharmacothérapie actuelle est souvent inefficace en raison du manque de connaissance de la pathophysiologie de la FA.Pour comprendre comment se réalise le remodelage atrial, une approche Omique qui explore le transcriptome, l'épigénome (méthylome et microOme) et le génome de patients atteints de FA a été réalisée. Parallèlement, le phénotype de vieux rats spontanément hypertendus (SHRs) a été caractérisé et une é

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2

Wijffels, Maurits Christoffel Emile Franciscus. "Atrial fibrillation begets atrial fibrillation an experimental study in chronically instrumented goats /." Maastricht : Maastricht : Universiteit Maastricht ; University Library, Maastricht University [Host], 1996. http://arno.unimaas.nl/show.cgi?fid=6751.

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3

Vaizurs, Raja Sarath Chandra Prasad. "Atrial Fibrillation Signal Analysis." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3386.

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Atrial fibrillation (AF) is the most common type of cardiac arrhythmia encountered in clinical practice and is associated with an increased mortality and morbidity. Identification of the sources of AF has been a goal of researchers for over 20 years. Current treatment procedures such as Cardio version, Radio Frequency Ablation, and multiple drugs have reduced the incidence of AF. Nevertheless, the success rate of these treatments is only 35-40% of the AF patients as they have limited effect in maintaining the patient in normal sinus rhythm. The problem stems from the fact that there are no me

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4

Anjos, Diana Sofia Pereira dos. "Ablation of atrial fibrillation." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62150.

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5

Anjos, Diana Sofia Pereira dos. "Ablation of atrial fibrillation." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62150.

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6

An, Yoshimori. "Causes of death in Japanese patients with atrial fibrillation: The Fushimi Atrial Fibrillation Registry." Doctoral thesis, Kyoto University, 2020. http://hdl.handle.net/2433/245817.

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7

Scholten, Marcoen Franciscus. "Topics in atrial fibrillation management." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2006. http://hdl.handle.net/1765/7636.

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8

Park, Helen Loreen. "Atrial fibrillation and cognitive impairment." Thesis, University of Newcastle Upon Tyne, 2004. http://hdl.handle.net/10443/765.

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Background In our aging population the burden of dementia is increasing, necessitating the urgent identification of treatable risk factors. Small cross-sectional studies demonstrate associations between nonvalvular atrial fibrillation (NVAF), silent cerebral infarction and decreased cognitive function, but there are few longitudinal studies in this area. This thesis reports the results of a prospective longitudinal cohort study of cognitive decline in people with recent-onset NVAF compared to controls. To inform the thesis, an extensive literature review was undertaken . This included searches

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9

Marrouf, Nedal. "Mitochondrial DNA in atrial fibrillation." Thesis, St George's, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415671.

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10

Själander, Sara. "Stroke prevention in atrial fibrillation." Doctoral thesis, Umeå universitet, Medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124951.

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Background: The Framingham Study from 1991 showed a clear correlation between atrial fibrillation (AF) and ischemic stroke, where patients with AF had an almost fivefold increase in risk of stroke compared with patients without AF. Since then, several trials have evaluated different antithrombotic treatments to reduce the risk of stroke in patients with AF. Other trials have investigated factors that increase the risk of stroke in patients with AF and risk score systems have been developed to categorize patients into low or increased risk of stroke to help clinicians to decide which patients b

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11

Ahlsson, Anders. "Atrial fibrillation in cardiac surgery." Doctoral thesis, Örebro universitet, Hälsoakademin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-2442.

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Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice. In cardiac surgery, one-third of the patients experience episodes of AF during the first postoperative days (postoperative AF), and patients with preoperative AF (concomitant AF) can be offered ablation procedures in conjunction with surgery, in order to restore ordinary sinus rhythm (SR). The aim of this work was to study the relation between postoperative AF and inflammation; the long-term consequences of postoperative AF on mortality and late arrhythmia; and atrial function after concomitant surgical ablation

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12

Kalifa, Jérôme. "Fibrillation auriculaire et étirement atrial." Aix-Marseille 2, 2007. http://www.theses.fr/2007AIX20655.

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La fibrillation auriculaire (FA) est fréquemment associée à la dilatation atriale cependant les mécanismes électrophysiologiques et métaboliques sont mal connus. Nous avons utilisé un modèle expérimental de FA suivant une augmentation aigüe de la pression intra-auriculaire. Avec des méthodes de cartographie optique nous avons montré que des sources électriques localisées dans la région postérieure de l’oreillette gauche maintiennent l’arythmie. L’étude des conséquences métaboliques de la FA liée au stretch a montré un état de dissociation entre production et utilisation de l’énergie. L’arrêt d

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13

Bonizzi, Pietro. "Atrial activity extraction and analysis in atrial fibrillation episodes." Nice, 2010. http://www.theses.fr/2010NICE4027.

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Atrial fibrillation (AF) as it affects up to 10% of people over 70 years of age is the most common cardiac arrhythmias encountered in clinical practice, in spite of its relevance and incidence, the mechanisms of initiation and maintenance of AF are still quite unknown. Different strategies for AF treatment are selected with respect to the duration of AF episodes, and their efficacy may also be influenced by the degree of organization in the atrial activity (AA). The degree of organization of the AA depends in turn on the chronification of AF, and on the consequent electro-structural remodeling

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14

VILA, MUHAMED. "ATRIAL COMPLEX NETWORKS IN ENDOCAVITARY RECORDINGS DURING ATRIAL FIBRILLATION." Doctoral thesis, Università degli Studi di Milano, 2022. http://hdl.handle.net/2434/932991.

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L'incidenza e la prevalenza delle malattie atriali, in particolare della fibrillazione atriale (FA), stanno raggiungendo oggi proporzioni pandemiche. Nonostante i notevoli sforzi di ricerca e i progressi compiuti nella comprensione dei meccanismi alla base della FA, la capacità di trattarla rimane problematica. Questa tesi si propone di contribuire a ridurre il peso dell'aritmia atriale dal punto di vista tecnico, elaborando i segnali elettrici provenienti dal cuore. In particolare, l'obiettivo principale di questa tesi è studiare tecniche di elaborazione dei segnali atriali invasivi che forni

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15

Holm, Magnus. "Chronic atrial fibrillation in man activation, organisation and characterisation /." Lund : Lund University, 1997. http://catalog.hathitrust.org/api/volumes/oclc/68945033.html.

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16

Hendrikx, Tijn. "Catch Atrial Fibrillation, Prevent Stroke : Detection of atrial fibrillation and other arrhythmias with short intermittent ECG." Doctoral thesis, Umeå universitet, Allmänmedicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100497.

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Background: Atrial fibrillation (AF) is the most common arrhythmia in the adult population, affecting about 5% of the population over 65 years. Occurrence of AF is an independent risk factor for stroke, and together with other cardiovascular risk factors (CHADS2/CHA2DS2- VASc), the stroke risk increases. Since AF is often paroxysmal and asymptomatic (silent) it may remain undiagnosed for a long time and many AF patients are not discovered before suffering a stroke. Aims: To estimate the prevalence of previously undiagnosed AF in an out-of-hospital population with CHADS2 ≥1, in patients with an

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17

Lee, Seungyup. "Mapping the Characteristics of Atrial Activation Patterns During Atrial Fibrillation." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1354634723.

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18

Davies, Edward John. "Current challenges in atrial fibrillation ablation." Thesis, University of Plymouth, 2016. http://hdl.handle.net/10026.1/8067.

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The ablative management of atrial fibrillation, despite a number of landmark discoveries, remains one of the most challenging fields in interventional electrophysiology. It is generally accepted that successful isolation of the pulmonary veins is a highly effective way of managing paroxysmal forms of AF. However, despite almost a decade of research into alternative lesion patterns, the solution to persistent AF remains beyond our grasp. A variety of strategies have been proposed to target key areas in the atria; these use various complex mapping systems, usually based on tailored lesion sets t

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19

Sin, Pui-yee. "Quality of life in atrial fibrillation /." View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36222562.

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20

Kirchhof, Carolus Jean Henri Jacques. "The sinus node and atrial fibrillation." Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5516.

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21

Nieuwlaat, Robby. "Management of atrial fibrillation in Europe." [Maastricht] : Maastricht : Universitaire Pers Maastricht ; University Library, Universiteit Maastricht [host], 2007. http://arno.unimaas.nl/show.cgi?fid=9174.

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22

Hijazi, Ziad. "New Risk Markers in Atrial Fibrillation." Doctoral thesis, Uppsala universitet, Institutionen för medicinska vetenskaper, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198833.

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Atrial fibrillation (AF) confers an independent increased risk of stroke and death. The stroke risk is very heterogeneous and current risk stratification models based on clinical variables, such as the CHADS2 and CHA2DS2VASc score, only offer a modest discriminating value. The aims of this thesis were to study cardiac biomarkers, cardiac troponin and natriuretic peptides e.g. N-terminal prohormone-B-type natriuretic peptide (NT-proBNP), and describe levels in AF patients, investigate the association with stroke or systemic embolism, cardiovascular event, major bleeding and mortality, and to as

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23

Sopher, Solomon Mark. "Non-pharmacological approaches to atrial fibrillation." Thesis, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511961.

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24

Sin, Pui-yee, and 冼佩儀. "Quality of life in atrial fibrillation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B45012878.

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25

Runnett, Craig. "Atrial fibrillation : prediction of successful cardioversion." Thesis, University of Newcastle Upon Tyne, 2007. http://hdl.handle.net/10443/768.

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Aim: Despite atrial fibrillation being the most commonly occurring sustained cardiac arrhythmia its treatment remains the subject of great debate. DC cardioversion is a treatment option often used to return normal cardiac function. We aimed to assess relapse rates following DC cardioversion and to determine whether transoesophageal echocardiography, P wave signal averaged electrocardiography or heart rate variability measurements had a role in identifying patients likely to relapse to atrial fibrillation. Methods: Patients who were referred for DC cardioversion of chronic non-valvular atrial f

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26

Almroth, Henrik. "Atrial fibrillation : inflammatory and pharmacological studies." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-22590.

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27

Gonia, Regina, and Regina Gonia. "Symptoms in Adults with Atrial Fibrillation Seeking Care in Emergency Department." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/626322.

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Atrial fibrillation is a common arrhythmia encountered in the emergency department. In the United States, newly diagnosed cases of atrial fibrillation is projected to be 2.6 million cases in 2030 and the annual prevalence of atrial fibrillation is expected to be 12.1 million in 2030 (Colilla et al., 2013). Patients may present to the emergency department for treatment of atrial fibrillation with a variety of symptoms and therefore makes diagnosing atrial fibrillation based on symptomatology challenging for the clinician. The primary goal of this Doctor of Nursing Practice (DNP) project is to d

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28

Khoo, Chee Wah. "The relationship between left atrial remodelling, atrial fibrillation burden and thrombogenesis." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6847/.

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Contemporary pacemakers allow quantification of atrial high-rate episodes (AHREs) and atrial fibrillation burden (AFB) accurately. It is generally believed that left atrial (LA) remodelling may precede the development of atrial arrhythmias (AA), and AHRE precede the clinical manifestation of atrial flutter or fibrillation. However, the relationship between LA remodelling with AHRE has not been studied. Furthermore, the relationship of AFB to progressive LA remodelling and how this relates to indices of thrombogenesis is unclear. The aim of my study is to investigate the inter-relationship betw

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29

Lellouche, Nicolas. "Fibrillation atriale : de la physiopathologie aux traitements actuels." Thesis, Paris Est, 2011. http://www.theses.fr/2011PEST0092/document.

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La fibrillation atriale (FA) est le trouble du rythme cardiaque le plus fréquent et dont la prévalence est en constante augmentation. Les extrasystoles déclenchant cette arythmie naissent le plus souvent des veines pulmonaires. Ainsi l’ablation des veines pulmonaires est devenue un traitement important de cette arythmie, surtout quand elle est paroxystique. Cependant le maintien de la FA est assuré par du substrat atrial pathologique.Le traitement endocavitaire de ce substrat comprend essentiellement l’ablation de potentielsfragmentés enregistrés en FA.Nous avons démontré que ces potentiels fr

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30

Boileve, Arthur. "Ιmplicatiοn des prοtéines EΡAC dans la régulatiοn de l'activité électrique des cardiοmyοcytes". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC404.

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Les Protéines d’Échange directement Activées par l’AMPc (EPAC) sont des effecteurs majeurs de la voie de l’AMPc. Dans le cardiomyocyte, les protéines EPAC interviennent dans la régulation de nombreuses fonctions cellulaires. Elles participent à la mise en place de processus hypertrophiques et à la régulation de l’homéostasie calcique en contribuant aux mécanismes de fuite de Ca2+ diastolique. Par ailleurs, les protéines EPAC concourent à moduler l’électrophysiologie cardiaque et la question de leur potentiel arythmogène a déjà été soulevée. Néanmoins, leur rôle exact dans la régulation de l’él

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31

Kamath, Sridhar. "A study of platelets in atrial fibrillation." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270055.

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32

Hemels, Martin Eric Willem. "Rhythm control strategies for symptomatic atrial fibrillation." [S.l. : Groningen : s.n. ; University Library of Groningen] [Host], 2007. http://irs.ub.rug.nl/ppn/305364359.

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33

Scridon, Alina. "Atrial fibrillation : insights concerning the arrhythmogenic substrate." Phd thesis, Université Claude Bernard - Lyon I, 2012. http://tel.archives-ouvertes.fr/tel-00933537.

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Atrial fibrillation is the most prevalent form of cardiac arrhythmia. Studies in animal modelshave provided important insights into arrhythmia mechanisms. However, to date, we do not dispose ofanimal models of spontaneous atrial arrhythmia.Thus, we aimed to develop a model of spontaneous atrial arrhythmia in rats and to assesspathophysiological mechanisms of these arrhythmias by using a multidisciplinary approach. We alsoaimed to assess the presence and the extent of inflammation and endothelial dysfunction, incriminatedin atrial fibrillation-related complications such as stroke, in atrial fib

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34

Ahmad, Anita. "Dominant frequency estimation for atrial fibrillation studies." Thesis, University of Leicester, 2012. http://hdl.handle.net/2381/10309.

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This research work explores the feasibility of using frequency domain analysis in the study of arrhythmias. The research involves the application of spectrum analysis to obtain the dominant frequency (DF) of atrial electrograms (AE) at different sites in the atria. It is an alternative way of interpreting the chaotic electrical activity seen during AF and reveals critical sites to guide ablation. As longer ablation procedure time implies higher risk to the patient, DF estimation needs to be obtained as quickly as possible. Four techniques (FFT, Blackman-Tukey, Autoregressive and Multiple Signa

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35

Kojodjojo, Pipin. "Substrate and triggers of human atrial fibrillation." Thesis, Institute of Cancer Research (University Of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498071.

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36

Siu, Chung-wah David, and 蕭頌華. "Current perspective of new-onset atrial fibrillation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45205322.

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37

Stegberg, Marcus. "Atrial fibrillation and the Cryo Maze procedure." Thesis, Örebro universitet, Institutionen för läkarutbildning, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-43001.

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38

Manoharan, G. "Cardioversion of atrial fibrillation : a novel approach." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395370.

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39

Guttmann, O. P. "Stroke and atrial fibrillation in hypertrophic cardiomyopathy." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1497024/.

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Hypertrophic cardiomyopathy (HCM) is an inherited myocardial disease associated with atrial fibrillation (AF) and thromboembolism (TE), which are related to adverse clinical outcomes and reduced survival. Current ESC and ACCF/AHA guidelines recommend anticoagulation in all patients with HCM and atrial fibrillation but the absolute risk of thromboembolism in patients with and without documented AF is unclear. The primary aim of this study was to derive and validate a model for estimating the risk of TE in HCM. Analyses were performed to determine predictors of AF and TE. Exploratory analyses as

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40

Taggar, Jaspal. "Screening for atrial fibrillation in primary care." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/44379/.

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Background: Screening for atrial fibrillation (AF) has been recommended but is yet to be implemented in clinical practice. However, the most effective approaches for screening are not known and it is unclear if screening could feasibly be implemented in primary care. Aims and methods The overall aims were to determine how AF screening might feasibly and effectively be introduced into primary care in the United Kingdom (UK). Objectives were: 1) to determine the range and accuracies of methods for detecting pulse irregularities attributable to AF, 2) to determine the range and accuracies of meth

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41

Smiley, Aref. "EVOLUTIONARY OPTIMIZATION OF ATRIAL FIBRILLATION DIAGNOSTIC ALGORITHMS." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1407025535.

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42

Liu, Zhao. "USING GENE THERAPY TO PREVENT ATRIAL FIBRILLATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1481231548493874.

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43

Rodrigo, Bort Miguel. "Non-invasive identification of atrial fibrillation drivers." Doctoral thesis, Universitat Politècnica de València, 2016. http://hdl.handle.net/10251/75346.

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Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. Nowadays the fibrillatory process is known to be provoked by the high-frequency reentrant activity of certain atrial regions that propagates the fibrillatory activity to the rest of the atrial tissue, and the electrical isolation of these key regions has demonstrated its effectiveness in terminating the fibrillatory process. The location of the dominant regions represents a major challenge in the diagnosis and treatment of this arrhythmia. With the aim to detect and locate the fibrillatory sources prior to surgical proce

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44

Johanson, Birgitta. "Aspects of intraoperative ablation for atrial fibrillation /." Göteborg : Dept. of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, Dept of Cardiology, Sahlgrenska University Hospital, University of Gothenburg, 2009. http://hdl.handle.net/2077/20441.

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45

Lee, Seungyup. "A RAPID CYCLE LENGTH VARIABILITY DETECTION TECHNIQUE OF ATRIAL ELECTROGRAMS IN ATRIAL FIBRILLATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1207255208.

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46

Sudlow, Christopher Mark. "The prevalence of atrial fibrillation in the UK and of suitability for warfarin treatment amongst those with atrial fibrillation." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301176.

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47

Núñez, García Marta. "Left atrial parameterisation and multi-modal data analysis: application to atrial fibrillation." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/664138.

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Many aspects related to the pathogenesis and progression of atrial fibrillation (AF) are still not fully understood. In this thesis we have contributed with (1) an automatic framework to segment the left atrium (LA) from late gadolinium enhancement magnetic resonance imaging (LGE-MRI) data, (2) a framework for obtaining a standardised two-dimensional representation of the left atrial cavity, and (3) a methodology to detect and measure the incompleteness of ablation lesions after pulmonary vein isolation (PVI). Finally, we applied our tools to real clinical datasets showing how our methods can

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48

Dawson, Kristin. "The regulation of atrial fibroblast behaviour and its role in atrial fibrillation." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123124.

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Atrial fibrillation (AF) is the most common type of arrhythmia. Altered electrical and structural properties of the heart give rise to the initiation and maintenance of AF. Structural remodeling is an important component of congestive heart failure (CHF). AF and CHF commonly occur together in patient populations. Cardiac fibroblasts are the main drivers of structural remodeling in the heart, through the generation of fibrosis by excess extracellular matrix (ECM) synthesis and deposition. Understanding fibroblast behaviour and designing strategies to regulate it could prevent adverse remodeling

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49

Guichard, Jean-Baptiste. "Déterminants du remodelage atrial et de son effet pro-arythmique dans la fibrillation atriale." Thesis, Lyon, 2019. http://hdl.handle.net/1866/24623.

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Rationnel et objectif - La fibrillation atriale (FA) est la pathologie rythmique supra-ventriculaire la plus fréquemment diagnostiquée. Le remodelage atrial, qu’il soit électrique ou structurel, conduit à la mise en place et au développement de la cardiomyopathie atriale. La cardiomyopathie atriale est responsable de différentes complications : d’une part mécaniques conduisant à l’augmentation du risque thrombo-embolique et de l’insuffisance cardiaque, d’autre part électriques conduisant à différentes arythmies atriales dont la FA. L’objectif du présent travail est de caractériser les détermin

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50

Haldar, Shouvik Kumar. "Interventional techniques in the management of atrial fibrillation." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/42251.

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Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with significant morbidity and mortality. Historically, anti-arrhythmic drug (AAD) therapy achieves sub-optimal efficacy. The last two decades have seen major advances in cardiac electrophysiology, with catheter ablation now becoming the treatment of choice for AF. However, although outcomes for paroxysmal AF are excellent, the optimal interventional strategy for patients with long-standing persistent atrial fibrillation (LSPAF) has yet to be determined. Catheter ablation in LSPAF can achieve a modest degree of su

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