Relevant bibliographies by topics / Auto-inducers

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Auto-inducers'

Author: Grafiati
Published: 24 August 2024
Last updated: 31 July 2025

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Journal articles on the topic "Auto-inducers"

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SHIN, Hwain, Kazuya OKADA, John C. WILKINSON, et al. "Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein." Biochemical Journal 373, no. 3 (2003): 965–71. http://dx.doi.org/10.1042/bj20030583.

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The execution phase of apoptosis is under the control of members of the inhibitor of apoptosis (IAP) family of zinc finger proteins. Several of these proteins contain a C-terminal RING (really interesting new gene) domain that has been postulated to regulate ubiquitination of themselves or their target proteins, thereby modulating thresholds for apoptosis. We demonstrate that the auto-ubiquitination sites of the X-linked IAP (XIAP) are Lys322 and Lys328, located in the third baculovirus IAP repeat domain of the protein. Modification of these sites to arginine dramatically reduces ubiquitinatio
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D.K., Choudhary, and Sandhu S.S. "Quorum Sensing (QS) As Etiological Phenomenon: The Bacterial Paradigm." PJSR 2, no. 2 (2009): 1–4. https://doi.org/10.5281/zenodo.8296428.

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Signaling mechanisms that govern physiological and morphological responses to change the cell density are common in bacteria. Quorum sensing is signal transduction processes which involves the production and release of and response to hormone-like molecules (auto-inducers) that accumulate in the external environment as the cell population grows. Quorum sensing is found in a wide variety of bacteria, both Gram-positive and Gram-negative and the spectrum of physiological functions that can be regulated is impressive. Variation in the nature of the extra-cellular signal in the signal detection ma
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Gonzalez-Chapa, Jorge Armando, Marina Barguil Macêdo, and Christian Lood. "The Emerging Role of Mitochondrial Dysfunction in the Pathogenesis of Idiopathic Inflammatory Myopathies." Rambam Maimonides Medical Journal 14, no. 2 (2023): e0006. http://dx.doi.org/10.5041/rmmj.10493.

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Increasing evidence points towards mitochondria as crucial players in the initiation and progression of auto-immune and degenerative disorders, to which impaired cell metabolism is but a facet of the subjacent etiopathogenesis. This review aims to introduce the reader to essential concepts of mitochondrial abnormalities in idiopathic inflammatory myopathy (IIM), underscoring inclusion-body myositis and dermatomyositis. Far surpassing the initial simplistic view of being responsible for energy generation, mitochondria have gathered attention regarding their role in inflammatory processes, being
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TANAKA, Motoyuki, Stephan R. Krutzik, Peter A. Sieling, Thomas H. Rea та Robert L. Modlin. "Fcγ receptor activation triggers monocytes to differentiate into CD1b+ immature dendritic cells (B138)". Journal of Immunology 178, № 1_Supplement (2007): LB29. http://dx.doi.org/10.4049/jimmunol.178.supp.b138.

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Abstract Antibodies are potent inducers of inflammation and Fcγ receptors (FcγRs) are considered as important immune-regulators linked to infection immunity, cancer immunity and auto-immunity. We previously reported that CD1b+ dendritic cells (DC) are differentially distributed in leprosy lesions and contribute to the in pathophysiology of the polarized clinical spectrum of the disease. Here we demonstrate that activation of FcγRs on human blood monocytes triggers monocyte differentiation into CD1b+ cells. The CD1b+ population increased in a dose-dependent manner, and the differentiation was b
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Morgan-Sagastume, Fernando, Nico Boon, Sofie Dobbelaere, Tom Defoirdt, and Willy Verstraete. "Production of acylated homoserine lactones byAeromonasandPseudomonasstrains isolated from municipal activated sludge." Canadian Journal of Microbiology 51, no. 11 (2005): 924–33. http://dx.doi.org/10.1139/w05-077.

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Up to now, the production and role of N-acyl homoserine lactones (AHLs) in activated sludge have been poorly understood. In this study, cross-feeding assays with the reporter strains Agrobacterium tumefaciens NTL4 and Chromobacterium violaceum CV026 were used to investigate AHL signal production by municipal activated sludge samples. AHL signal production was consistently detected from municipal activated sludge when different samples were incubated on nutrient media. From one municipal activated sludge sample, 10 strains producing AHL-like auto inducers were isolated by an overlay technique.
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Haniyya, Haniyya, Dini Achnafani, Maria Ulfah, Niknik Nurhayati, and Is Helianti. "The utilization of auto-inducible Plyb promoter and media optimation for cell density-dependent expression of recombinant xylanase in Bacillus subtilis DB104." Microbiology Indonesia 14, no. 1 (2020): 2. http://dx.doi.org/10.5454/mi.14.1.2.

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Strong promoters are one of the fundamental aspects to increase the level of gene expression, and one of approach to improve the recombinant enzyme productivity so that the efficiency of production cost for enzyme production in industrial scale can be reached. Here we assessed the application of a cell density-dependent promoter and media optimation to promote cell growth and protein expression of Bacillus subtilis without excess usage of inducers. An auto-inducible Pylb promoter that is potential to provide inducer-free enzyme production was cloned and introduced into xylanase recombinant sys
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Hetta, Helal F., Yasmin N. Ramadan, Zainab I. Rashed, et al. "Quorum Sensing Inhibitors: An Alternative Strategy to Win the Battle against Multidrug-Resistant (MDR) Bacteria." Molecules 29, no. 15 (2024): 3466. http://dx.doi.org/10.3390/molecules29153466.

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Antibiotic resistance is a major problem and a major global health concern. In total, there are 16 million deaths yearly from infectious diseases, and at least 65% of infectious diseases are caused by microbial communities that proliferate through the formation of biofilms. Antibiotic overuse has resulted in the evolution of multidrug-resistant (MDR) microbial strains. As a result, there is now much more interest in non-antibiotic therapies for bacterial infections. Among these revolutionary, non-traditional medications is quorum sensing inhibitors (QSIs). Bacterial cell-to-cell communication
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Noori, Noorgul, Ahmad Wali Ataye, Abdul Musawer Bayan, Rafiullah Shirzadi, and Mohammad Esmail Ahmadyar. "Structural Insights into Taxifolin's Potential Inhibition of AHL Synthase via Molecular Docking and Dynamics Simulations." Afghanistan Journal of Basic Medical Science 2, no. 1 (2025): 24–36. https://doi.org/10.62134/khatamuni.53.

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Background: The extensive application of antibiotics for bacterial disease treatment has resulted in the emergence of antibiotic resistance and biofilm formation, a significant issue that contributes to increased illness and death rates. Quorum sensing (QS) is cell-cell communication in bacteria involved in the formation of biofilm in which this pathway is triggered by signaling molecules called auto inducers. Inhibition of enzymes that produce such signaling molecules, for instance, acyl-homoserine lactone synthase (AHL) in QS would be appreciable to enhance the effect of antibiotics and prev
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Naik, Varsha, and Girish Mahajan. "Quorum Sensing: A Non-conventional Target for Antibiotic Discovery." Natural Product Communications 8, no. 10 (2013): 1934578X1300801. http://dx.doi.org/10.1177/1934578x1300801030.

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Quorum sensing (QS) is known to regulate different functions viz. pathogenesis, biofilm formation, and host colonization, along with other functions by regulating bacterial virulence determinants. Therefore, QS is deemed to be an interesting target to modulate pathogenesis. Also, there have been global reports of continuous emergence of antibiotic-resistant microbes; hence, an alternative treatment that compliments antibiotic activity is highly desirable. One such approach is to look for QS inhibitors, which can quench the virulence phenotypes exerted by pathogenic bacteria and compliment anti
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Mujawdiya, Pavan K., and Suman Kapur. "Modulation of Gut Microbiota through Dietary Phytochemicals as a Novel Anti-infective Strategy." Current Drug Discovery Technologies 17, no. 4 (2020): 498–506. http://dx.doi.org/10.2174/1570163816666191107124214.

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: Quorum Sensing (QS) is a phenomenon in which bacterial cells communicate with each other with the help of several low molecular weight compounds. QS is largely dependent on population density, and it triggers when the concentration of quorum sensing molecules accumulate in the environment and crosses a particular threshold. Once a certain population density is achieved and the concentration of molecules crosses a threshold, the bacterial cells show a collective behavior in response to various chemical stimuli referred to as “auto-inducers”. The QS signaling is crucial for several phenotypic
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Dissertations / Theses on the topic "Auto-inducers"

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Dupont, Charly. "Caractérisatiοn mοléculaire des mécanismes de cοmmunicatiοn aérienne chez la sοuche Ρseudοmοnas fluοrescens ΜFE01". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMR021.

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Les composés organiques volatils (COV), sous-produits du métabolisme émis par l’ensemble desorganismes vivants, sont volatils en conditions environnementales en raison de leurs propriétés physicochimiques.Chez les bactéries, et notamment celles du genre Pseudomonas, les COV sontprincipalement étudiés pour leur capacité à inhiber des microorganismes phytopathogènes. Leur rôledans la communication, un mécanisme indispensable à la coordination des communautés bactérienneslors de la formation de biofilm, est rarement considéré.L'objectif des travaux menés est l'analyse les COVs produits par la sou
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Book chapters on the topic "Auto-inducers"

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Sundar, Kothandapani, Ramachandira Prabu, and Gopal Jayalakshmi. "Quorum Sensing Inhibition Based Drugs to Conquer Antimicrobial Resistance." In The Global Antimicrobial Resistance Epidemic - Innovative Approaches and Cutting-Edge Solutions [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104125.

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Quorum sensing is the cell to cell communication mechanism in microorganism through signalling molecules. Regulation of virulence factor, sporulation, proteolytic enzymes production, biofilm formation, auto-inducers, cell population density are key physiological process mediated through quorum-sensing (QS) signalling. Elevation of innate immune system and antibiotic tolerance of pathogens is highly increased with perspective of quorum-sensing (QS) activity. Development of novel drugs is highly attractive scenario against cell-cell communication of microbes. Design of synthetic drugs and natura
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Dwivedi, Deepak, and Trishla Sehgal. "Biofilm Development in Gram-Positive and Gram-Negative Bacteria." In Bacterial Biofilms [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104407.

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Biofilms are the communities of microorganisms, especially bacteria attached to a biotic or abiotic surface. These biofilms live in a self-sustained matrix and produce different substances called extracellular polymeric substances (EPS) which are responsible for the pathogenicity of a number of bacteria such as Pseudomonas aeruginosa, Staphylococcus aureus, Vibrio cholerae, Klebsiella pneumoniae, Escherichia coli, etc. These EPS substance makes it difficult to eradicate the biofilm present on the surface. Biofilm formation is a five-step process. Biofilms can be monospecies or multispecies. In
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Conference papers on the topic "Auto-inducers"

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Schleuning, W. D. "THE BIOCHEMISTRY AND CELL BIOLOGY OF SINGLE CHAIN UROKINASE TYPE PLASMINOGEN ACTIVATOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642956.

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Urokinase was discovered in the late nineteenth century, as an enzymatic principle in urine, that initiates the dissolution of blood clots. The basis of this phenomenon was recognized more than fifty years ago as the activation of plasminogen, the precursor of a tryptic protease, then known as profibrinolysin. Despite this long history, detailed data on the biochemistry of plasminogen activation have only become available recently. Urokinase (now designated urokinase-type plasminogen activator : u-PA) is synthesized and secreted as a single chain polypeptide (Mr-: 53,000) by many cell types. S
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