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Dissertations / Theses on the topic 'Autoimmune Disorders in Pregnancy'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Vaidya, Bijayeswar. "Genetics of autoimmune endocrine disorders." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341439.

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2

Hill, Becky Carolynn. "Eating disorders during pregnancy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq22744.pdf.

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3

Sarberg, Maria. "Sleep disorders during pregnancy." Doctoral thesis, Linköpings universitet, Avdelningen för kliniska vetenskaper, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-117869.

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Background Sleep disorders are known to increase in prevalence during pregnancy, and associations between disturbed sleep during pregnancy and adverse outcomes for mother and child have been reported in a number of studies. However, most of these studies were retrospective and too small to satisfactorily demonstrate the association. Aims To prospectively investigate the development of snoring during pregnancy and assess if there is an association between snoring and sleepiness or adverse pregnancy outcomes. To study the development of restless legs syndrome during and after pregnancy, and whe

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4

Indugula, Reshmi. "Fungal Exposure and Development of Autoimmune Disorders." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1505124409594398.

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5

Werner, Mårten. "Autoimmune hepatitis in Sweden /." Umeå : Univ, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-18545.

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6

Werner, Mårten. "Autoimmune hepatitis in Sweden." Doctoral thesis, Umeå universitet, Medicin, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-18545.

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Autoimmune hepatitis (AIH) was identified as an entity by the Swedish professor Jan Waldenström in the 1950s. It was then denoted lupoid hepatitis, characterized by liver inflammation and most often affecting young women. During the years the diagnosis has become more defined (as the non A non B hepatitis has been identified as Hepatitis C) and now can be safely separated from other diseases with liver inflammation. Studies of epidemiological data and long term prognosis have been scarce in the literature. Within a collaboration between the university hospitals in Sweden, we collected what we

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7

Nama, Vivek. "Microvascular circulation in pregnancy-associated hypertensive disorders." Thesis, St George's, University of London, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604010.

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Preeclampsia (PE) is the commonest hypertensive disorder seen in pregnancy and is a significant cause for maternal mortality and morbidity world wide. Its impact on perinatal morbidity and mortality is difficult to measure. It is a well known fact that women who develop PE are at an increased risk of essential hypertension and other cardiovascular mortality like stroke and heart attacks. Recent literature has suggested that women who develop PE have increased markers of cardiovascular disease at the time of booking their pregnancy. We have previously demonstrated that reduction in capillary de

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8

Ekström, Smedby Karin. "Ultraviolet light, autoimmune disorders and the etiology of malignant lymphomas /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-313-2/.

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9

Spillane, J. "Clinical and functional studies of autoimmune disorders of neuromuscular transmission." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1461232/.

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Inherited and acquired disorders of the neuromuscular junction are an important cause of muscle weakness and fatigability. In this thesis I focus on the autoimmune disorders of neuromuscular transmission. Myasthenia Gravis (MG) is the most common of these diseases and is typically caused by antibodies against the post-synaptic acetylcholine receptor. Lambert Eaton Myasthenic Syndrome (LEMS) is a pre-synaptic disorder typically caused by antibodies against voltage gated calcium channels (VGCC). With regard to LEMS, my main aim was to gain a more complete understanding of the pathomechanisms of

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10

Norsworthy, Peter John. "The role of antibodies to complement component C1Q in the pathogenesis of SLE and hypocomplementemic urticarial vasculitis." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265253.

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11

Ono, Sachiko. "Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225507.

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12

Sakthivel, Priya. "Co-stimulatory molecules : genes to protein in autoimmune and inflammatory disorders /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-425-9/.

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13

Lackey, David Bruce. "Characterisation of interferon in systematic lupus erythematosus and other autoimmune disorders." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47525.

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14

Vidler, Marianne. "Community perceptions of the hypertensive disorders of pregnancy." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61169.

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Background: Two to four percent of pregnancies are affected by pre-eclampsia, the most serious of the hypertensive disorders of pregnancy. This results in a significant health burden, which disproportionately affects those in low- and middle-income countries. Research has largely focused at the facility level; however, such an approach does not address underlying beliefs and cultural practices. The aim of this dissertation is to explore community perceptions of the hypertensive disorders of pregnancy, with a focus on Nigeria, Mozambique, Pakistan and India. Methods: An ethnographic rese

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15

Diaz, Sílvia de Oliveira. "Pregnancy and newborns disorders followed by urine metabolomics." Doctoral thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13110.

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Doutoramento em Química<br>Chapter 1 introduces the scope of the work by identifying the clinically relevant prenatal disorders and presently available diagnostic methods. The methodology followed in this work is presented, along with a brief account of the principles of the analytical and statistical tools employed. A thorough description of the state of the art of metabolomics in prenatal research concludes the chapter, highlighting the merit of this novel strategy to identify robust disease biomarkers. The scarce use of maternal and newborn urine in previous reports enlightens the relevance

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16

Bulfoni, C. "BIOELECTRICAL IMPEDANCE ANALYSIS AND HYPERTENSIVE DISORDERS OF PREGNANCY." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/334672.

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Bioelectrical impedance analysis and hypertensive disorders of pregnancy Camilla Bulfoni Purpose Hypertensive disorders in pregnancy (HDP) are important causes of morbidity and mortality in pregnancy. Maternal cardiovascular system adapts to pregnancy, thanks to complex physiological mechanisms that involve cardiac output, total vascular resistance and water body distribution. In absence of an adaptation of the maternal cardiovascular systems pregnancy advances, there is an increased risk of fetal growth restriction and pregnancy induced hypertension. Bioelectrical impedance

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17

Bensing, Sophie. "Pituitary autoantibodies in endocrine disorders /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-478-3/.

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18

Papenfuss, Tracey L. "Hormones and dendritic cells influences on the initiation of the autoimmune disease experimental autoimmune encephalomyelitis /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1173196704.

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19

Peng, Huaizheng. "The molecular basis of high-grade transformation of B cell lymphoma of mucosal associated lymphoid tissues." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299696.

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20

Villanueva, Marta Janer. "A population study of genetic susceptibility to the autoimmune myasthenias." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294378.

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21

Chan, Koon-ho. "Neuronal and muscle autoantibodies in paraneoplastic neurological disorders and autoimmune myasthenia gravis." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557091.

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22

Brown, Thomas James. "Autoimmunity to glutamate decarboxylase in insulin-dependent diabetes and other autoimmune disorders." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308852.

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23

Chan, Koon-ho, and 陳灌豪. "Neuronal and muscle autoantibodies in paraneoplastic neurological disorders and autoimmune myasthenia gravis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557091.

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24

Funabiki, Masahide. "Autoimmune Disorders Associated with Gain of Function of the Intracellular Sensor MDA5." Kyoto University, 2014. http://hdl.handle.net/2433/189355.

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25

Wesström, Jan. "Sleep Related Movement Disorders : Association with Menopause and Pregnancy." Doctoral thesis, Uppsala universitet, Obstetrik & gynekologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-204149.

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It is known that sleep problems affect people’s wellbeing and has great consequences for public health. Restless legs syndrome (RLS) gives uncomfortable sensations in the legs at rest, leading to an irresistible need for activity. It aggravates in evening and at night. Therefore, RLS provides poorer sleep and can affect quality of life through fatigue, family life and social activities, work, and comorbidity. It is demonstrated a dysfunction of the dopaminergic system in the brain with low levels of dopamine and / or less sensitive dopamine receptors. RLS is more common in women and the preval

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26

McClain, Melanie A. "Pregnancy and the post-partum period regulate experimental autoimmune encephalomyelitis through immunoregulatory cytokine production." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1119898792.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xv, 95 p.; also includes graphics (some col.) Includes bibliographical references (p. 85-95). Available online via OhioLINK's ETD Center

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27

Maddison, Paul. "A quantitative study of the immune-mediated neuromuscular disorders of acquired neuromyotonia and Lambert-Eaton myasthenic syndrome." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285378.

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28

Lindoff, Claes. "Haemostasis during pregnancy and perimenopausal age studies of fibrinolytic components and coagulation factors involved in vascular disease /." Lund : Dept. of Obstetrics and Gynaecology, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39750405.html.

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29

Dick, Andrew David. "Immunomodulation of experimental autoimmune uveoretinitis (EAU) : a model of tolerance induction with retinal antigens." Thesis, University of Aberdeen, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335521.

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Idiopathic endogenous posterior uveitis encompasses a spectrum of chronic intraocular inflammatory disorders which are thought to be autoimmune in nature. The animal model experimental autoimmune uveoretinitis (EAU) is mediated by CD4+ T-lymphocytes, and has proved invaluable in the study of the underlying immunopathogenesis of uveitis and alternative immunosuppressive therapies, for example, oral tolerance induction. This thesis describes, in a model of retinal-extract induced EAU, the effects of intranasal administration of retinal antigens prior to induction of EAU with retinal extract. The

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30

Abdul-Kadir, Rezan Ahmed. "Inherited bleeding disorders in obstetrics and gynaecology." Thesis, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391628.

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31

Easter, Abigail. "Maternal eating disorders : effects on pregnancy, infant and child development." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/maternal-eating-disorders(2b409d22-e80f-4538-b904-17060c23b63c).html.

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There is evidence that Eating Disorders (ED) may have implications for fertility, pregnancy and, diet and growth in their children. However, few large longitudinal investigations have been conducted. Women with ED have an increased risk for adverse obstetric outcomes; one proposed pathway is via elevated psychopathology during pregnancy, and consequently foetal overexposure to cortisol and corticotrophin-releasing-hormone, which may in turn have implications for stress regulation in their children. The aim of this thesis was to investigate the effects of ED on fertility and pregnancy, as well

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32

Cairns, Alexandra. "Management of hypertensive disorders of pregnancy in the postpartum period." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:225080ea-e240-45d4-81be-ecb8e649b94f.

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This thesis aimed to explore whether self-management techniques, effective in essential hypertension, could be applied to women with hypertensive disorders of pregnancy postpartum (HDP). HDP affect one in ten pregnancies, remain a leading cause of maternal death worldwide and are associated with elevated long-term maternal cardiovascular risk. Hypertension often persists postpartum and complications can occur. During the puerperium, multiple stresses on new mothers and their healthcare professionals can distract from good quality blood pressure (BP) management. Transfer of responsibility, from

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33

Pinto, Joana Isabel Monteiro. "Healthy pregnancy and prenatal disorders followed by blood plasma metabolomics." Doctoral thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/14784.

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Doutoramento em Bioquímica<br>The work presented in this thesis aimed to investigate the impact of healthy pregnancy and selected prenatal disorders on the metabolome and lipidome of maternal blood plasma, in order to define new potential biomarkers for non-invasive prediction and diagnosis. Chapter 1 describes the present status and challenges of the clinically relevant prenatal disorders, along with a presentation of the metabolomics strategy applied and the state of the art of metabolomics in prenatal research. All experimental details are described in Chapter 2, comprising sample metadata

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34

Kehler, Stephanie A. "Examining Biological and Psychological Variables in Hypertensive Disorders of Pregnancy." UKnowledge, 2017. http://uknowledge.uky.edu/nursing_etds/32.

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Despite advances in obstetric care, hypertensive disorders continue to complicate pregnancies at a high rate. Worldwide, hypertensive disorders affect up to 10% of pregnancies. The United States has seen a 25% increase in the incidence of hypertensive disorders over the last two decades (American College of Obstetricians and Gynecologists, 2017). These complications constitute one of the greatest causes of maternal and perinatal morbidity and mortality with an estimated 50,000 to 60,000 deaths per year across the world (American College of Obstetricians and Gynecologists, 2017). Although the e

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35

Gelaye, Bizu, Yinnan Zheng, Maria Elena Medina-Mora, Marta B. Rondón, Sixto E. Sánchez, and Michelle A. Williams. "Validity of the posttraumatic stress disorders (PTSD) checklist in pregnant women." Biomed Central Ltd, 2017. http://hdl.handle.net/10757/622252.

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Abstract BACKGROUND: The PTSD Checklist-civilian (PCL-C) is one of the most commonly used self-report measures of PTSD symptoms, however, little is known about its validity when used in pregnancy. This study aims to evaluate the reliability and validity of the PCL-C as a screen for detecting PTSD symptoms among pregnant women. METHODS: A total of 3372 pregnant women who attended their first prenatal care visit in Lima, Peru participated in the study. We assessed the reliability of the PCL-C items using Cronbach's alpha. Criterion validity and performance characteristics of PCL-C were assessed

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36

Fetah, Alija. "Mutations E688K and G569R within the NALP3 gene, associated with development of hereditary auto inflammatory disorders." Thesis, Högskolan i Skövde, Institutionen för vård och natur, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-4246.

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Different mutations within the NALP3 gene are thought to be associated with development of several types of hereditary auto inflammatory disorders such as neonatal onset multisystem inflammatory disorder (NOMID) and muckle-wells syndrome (MWS). In this work two separate mutations E688K and G569R were supposed to be constructed by site-directed mutagenesis in the cloned wild type NALP3 genes and further expressed in bacterial and mammalian host cells for functional studies in protein -protein interaction models.

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37

Turner, Emmitt, Darshan Shah, Kathryn L. Duvall, David L. Wood, and Beth Bailey. "Perinatal Outcomes of Marijuana use on Opioid Exposed Pregnancy." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/46.

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The prevalence of opioid use has increased in many populations including pregnant women, which has led to a substantial rise in infants born dependent on opioids due to in utero exposure. Many women use multiple substances aside from opioids during pregnancy, and their infants therefore present with a variety of symptoms. With increasing legalization and changing perception of marijuana, it has become one of the most commonly used substances during pregnancy. Few studies have evaluated concomitant use of marijuana and opioids in pregnancy despite both being implicated in adverse newborn outcom

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38

Crossley, Alison Rachel. "Immunological parameters in immune thrombocytopenic purpura and the effects of alpha interferon therapy." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308323.

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39

Shennan, Andrew Hoseason. "Ambulatory blood pressure measurement in pregnancy and pre-eclampsia." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286663.

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40

Seamans, Jennifer. "Experiences of pregnancy for women with eating disorders : a qualitative investigation." Thesis, Lancaster University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421846.

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Eating disorders occur primarily in young women, many of whom are of child bearing age. Pregnancy has often been viewed as a period of great developmental change for women. Many psychological processes such as body image, autonomy, dependency and relationships to one's own parents, which have been hypothesised to be important in the development of eating disorders, are highlighted during pregnancy. This may mean that pregnancy is a particularly stressful time for women with eating disorders. The limited amount of previous research in this area has suggested the potential for pregnancy to exert

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41

Winter, Kelly M. "Elucidating the Role of Neighborhood Deprivation in Hypertensive Disorders of Pregnancy." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3798.

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This dissertation examined risk factors for hypertensive disorders of pregnancy (HDP) — specifically whether neighborhood socioeconomic deprivation exacerbates individual socioeconomic disadvantage (deprivation amplification) to increase the likelihood of developing HDP. To select the optimal areal unit at which to investigate HDP, geographic proxies for neighborhoods were explored. A thematic review qualitatively examined nontraditional neighborhood boundaries identified through internet sources. Data from 2008–2012 Miami-Dade County, Florida birth records (n=121,421) and the U.S. Census Bure

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42

Frith, P. A. F. "A study of eye involvement in autoimmune and inherited disorders of the basement membrane zone." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599235.

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43

Pilli, Deepti. "The Autoimmune T cell Response Against the Dopamine-2 Receptor in Movement and Psychiatric Disorders." Thesis, The University of Sydney, 2020. https://hdl.handle.net/2123/22465.

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Autoimmunity and immune dysregulation are associated with a subset of movement and psychiatric disorders. This paradigm is largely supported by the discovery of autoantibodies against neuronal antigens, like the dopamine-2 receptor (D2R). T cells are a prominent cell subset in the immune system, however, their role in these diseases is unknown. Herein, we identified and characterised D2R-specific T cells in movement and psychiatric disorders in children and adults. In children with suspected autoimmune or neurodevelopmental movement and psychiatric disorders (n=24), activated D2R-specific T ce

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44

Knight, Marian. "Syncytiotrophoblast microvillous membrane deportation in the pathogenesis of pre-eclampsia." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389045.

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45

BONFIGLIO, RITA. "Inflammatory disorders in pregnancy at the time of placentation: relevance of PTX3." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2013. http://hdl.handle.net/2108/203166.

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46

Willis, Catherine Cecelia. "Regulation of cytokine production by peripheral blood monocytes in normal pregnancy and pre-eclampsia." Thesis, The University of Sydney, 2003. https://hdl.handle.net/2123/27988.

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Pre-eclampsia is a common disorder, specific to human pregnancy and a major cause of maternal and neonatal morbidity and mortality. The cause is unknown but the syndrome is thought to be the result of generalised endothelial dysfunction. There is increasing evidence that the maternal innate immune system may be involved in this systemic response. Peripheral blood monocytes, exquisitely sensitive cells pivotal to the immunosurveillance role of the innate immune system, interact with genetically different fetal derived cells, cellular organelles and secreted products throughout pregnancy.

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47

Gatson, Na Tosha Na Chole. "Sex, pregnancy, and a great pair of genes critical mediators in the development and progression of CNS autoimmune injury /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1195488191.

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48

Hertwig, Laura. "The implication of natural killer cells and neutrophils in autoimmune disorders of the central nervous system." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17591.

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Die genaue Implikation natürlicher Killer(NK)-zellen und Neutrophile in Autoimmunerkrankungen des zentralen Nervensystems (ZNS) ist nach wie vor ungeklärt und wurde daher im Mausmodell der multiplen Sklerose (MS), der experimentellen Autoimmunenzephalomyelitis (EAE), sowie bei MS und Neuromyelitis optica (NMO) Patienten untersucht. Bei MS Patienten konnte eine mit der Krankheitsaktivität korrelierende, reduzierte Zahl zirkulierender CX3CR1+NK Zellen festgestellt werden. Daher wurden die NK Zell-Dynamiken und der Einfluss von CX3CR1 auf diese im EAE Mausmodell untersucht. Hierbei konnte in Wil

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49

Churchill, David. "Twenty four hour ambulatory blood pressure monitoring in pregnancy." Thesis, University of Birmingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391325.

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50

Elfström, Peter. "Associated disorders in celiac disease." Doctoral thesis, Örebro universitet, Hälsoakademin, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-5223.

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Background: Celiac disease (CD) is an autoimmune disorder that affects genetically susceptible individuals and is induced by dietary gluten. Treatment consists of a lifelong gluten-free diet. CD is common and affects about 1% of the general population. The classic symptoms include diarrhea and malabsorption, but many patients have only mild symptoms or no symptoms at all. The proportion of individuals presenting with atypical symptoms or discovered only when investigating an associated condition of CD is increasing. Aims: The aim of this thesis was to investigate the risk of possible associate

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