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Journal articles on the topic 'Autoimmune Disorders in Pregnancy'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kiss, Emese, Csaba György Kiss, and Gyula Poór. "Systemic autoimmune disorders and pregnancy." Orvosi Hetilap 152, no. 43 (2011): 1715–23. http://dx.doi.org/10.1556/oh.2011.29216.

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The coincidence of systemic autoimmune diseases and pregnancy may modify the outcome of the disease and the pregnancy due to the background immunologic and hormonal processes. The great majority of patients with autoimmune diseases are young females in their reproductive ages willing to have babies. Consequently we have to prepare for this special situation. Our concept on childbearing in autoimmune women has changed within the last 30 years. Earlier, systemic lupus erythematosus flared in about 50% of patients during pregnancy, but the flare rate has significantly decreased recently. This imp

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Motha, Carmeline, Thilina S. Palihawadana, and Alastair McKelvey. "Pregnancy and autoimmune connective tissue disorders." Sri Lanka Journal of Obstetrics and Gynaecology 35, no. 4 (2014): 93. http://dx.doi.org/10.4038/sljog.v35i4.6581.

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Singhal, Neha, Alka S. Gupta, and Madhva Prasad. "Clinical presentation of autoimmune disorders in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 12 (2017): 5401. http://dx.doi.org/10.18203/2320-1770.ijrcog20175250.

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Background: Autoimmune disorders have a significant impact over the health of an individual. This heterogenous group of disorders affects pregnancy in a multitude of ways. Pregnancies with autoimmune disorders are usually cared for by a multidisciplinary team of doctors.Methods: Pregnancies with autoimmune disorders were studied over a one-year period in one unit of a medical college teaching hospital set up. Obstetric and neonatal outcomes were studied.Results: Ten patients were studied. Average age was 29.9 years. Majority presented in early second trimester. Eight patients were ANA positive

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Kushner, Carolyn J., Josef Symon S. Concha, and Victoria P. Werth. "Treatment of Autoimmune Bullous Disorders in Pregnancy." American Journal of Clinical Dermatology 19, no. 3 (2018): 391–403. http://dx.doi.org/10.1007/s40257-018-0342-0.

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Gudovic, Aleksandra, Svetlana Spremovic-Radjenovic, Gordana Lazovic, Jelena Marinkovic, Andreja Glisic, and Srboljub Milicevic. "Maternal autoimmune thyroid disease and pregnancy complication." Vojnosanitetski pregled 67, no. 8 (2010): 617–21. http://dx.doi.org/10.2298/vsp1008617g.

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Background/Aim. Thyroid disorders exert a great impact on pregnancy course and outcome. The aim of the study was to investigate impact of autoimmune thyroid disorders on pregnancy course and outcome, frequency of pregnancy complications and pregnancy loss. Methods. We followed 63 pregnancies prospectively during the period 1985-2007, 28 with hyperthyroid and 15 with hypothyroid autoimmune disorders, and 20 healthy pregnancies. Follow up included clinical, sonographic and laboratory investigations, including OGTT and postprandial glicemia. Results. There was no difference between previous prete

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Riache, R., and L. Smyshnikova. "FETAL MICROCHIMERISM: IMMUNOLOGICAL IMPLICATIONS IN AUTOIMMUNE DISORDERS." Sciences of Europe, no. 133 (January 27, 2024): 15–20. https://doi.org/10.5281/zenodo.10575539.

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Autoimmune diseases exhibit a higher prevalence among women beyond the age of 30, with a significantproportion occurring in women who have experienced at least one pregnancy. While the gestational period involves a shared circulation between the mother and the fetus for nine months, extensive research has elucidatedthe presence of fetal cells within maternal blood even years after the pregnancy. Although these phenomena arenow widely acknowledged in the scientific community, the persistence and potential consequences of fetal DNAwithin the maternal circulation remain topics of ongoing debate a

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S., Maheswari, Poornima C., and Seetha Panicker. "Review of 113 cases of autoimmune disorders in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4786. http://dx.doi.org/10.18203/2320-1770.ijrcog20195321.

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Background: Autoimmune disorders are chronic multisystem disorders affecting women of their reproductive age. Pregnancy among these women is complicated by the disease itself. Flaring up of disease, uteroplacental insufficiency due to vasculitis and drugs used for treatment are main reason for unfavourable pregnancy outcomes. The objective of this study was to analyze the pregnancy complications and outcome among 113 cases of autoimmune disorders.Methods: This study is a retrospective analysis of case records of pregnant women with autoimmune disorders. This study was conducted at PSG IMSR and

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BORRADORI, L., and J. SAURAT. "WS057 Atypical autoimmune subepidermal blistering disorders of pregnancy." Journal of the European Academy of Dermatology and Venereology 9 (September 1997): S90. http://dx.doi.org/10.1016/s0926-9959(97)89216-1.

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9

М., С. Черенько, and М. Черенько С. "MANAGEMENT OF THYROID DISORDERS DURING AND AFTER PREGNANCY." REPRODUCTIVE ENDOCRINOLOGY, no. 45 (February 28, 2019): 14–18. https://doi.org/10.18370/2309-4117.2019.45.14-18.

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The state of the art review of the recent recommendations of American Thyroid Association and Endocrine Society comprehensively elucidates the most important issues of management of pregnant women with thyroid disorders. Authors shown that not only pregnancy impact thyroid function and course of thyroid diseases, but also functional thyroid changes can seriously affect mother and fetus. Thyroid stimulating hormone levels are significantly reduced by 0.1–0.4 mIU/ml for the lower limit of norm and by 1.0 mIU/ml for the upper in I trimester of pregnancy under the influence of placental chor

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Cheenepalli, Anuradha, and Andallu Ratnam. "Maternal and perinatal outcome in autoimmune disorders complicating pregnancy." International Journal of Recent Scientific Research 08, no. 05 (2017): 17227–29. http://dx.doi.org/10.24327/ijrsr.2017.0805.0309.

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11

Mecacci, Federico, Annalisa Pieralli, Barbara Bianchi, and Michael J. Paidas. "The Impact of Autoimmune Disorders and Adverse Pregnancy Outcome." Seminars in Perinatology 31, no. 4 (2007): 223–26. http://dx.doi.org/10.1053/j.semperi.2007.05.005.

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12

Dr., Halah Abdul Wahab Mohammed, Afrah Naser kadhim Almusawi Dr., and Rawya Mansoor Abdullah Dr. "Immune System Disorders on Women's Fertility and Identifying Risk Factors." Sarcouncil Journal of Medical Series 3, no. 5 (2024): 41–47. https://doi.org/10.5281/zenodo.11379268.

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A cross-sectional study was conducted in different hospitals in Iraq, involving 110 cases from various hospitals, with the objective of diagnosing autoimmune disorders and their impact on fertility in Iraqi women from March 2023 to February 2024. The study employed a descriptive approach to assess the impact of treatment on women and identify any negative effects after pregnancy. A questionnaire comprising 50 items was distributed to patients, covering personal information, primary immunodeficiency diseases, family experiences, perceptions of fertility and childbirth, and the influence of immu

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13

Rima, Shakila Zaman, SM Moinul Islam, Nazmun Nahar, et al. "Autoimmune Thyroiditis in Women of Child Bearing Age and its Association with Thyroid Function and Thyroid Antibody Status." Bangladesh Journal of Nuclear Medicine 17, no. 1 (2015): 14–24. http://dx.doi.org/10.3329/bjnm.v17i1.22487.

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Thyroid disorders are prevalent in women of childbearing age and for this reason commonly present in pregnancy and the puerperium. Chronic autoimmune thyroiditis (AIT) is the most common and extensively studied organ-specific autoimmune disorder and it has important consequences on fertility, the occurrence of pregnancy complications and pregnancy outcome. Across sectional analytical study has been carried out on autoimmune thyroiditisamong the women of child bearing age with suspected thyroid disorders in the Centre for Nuclear Medicine & Ultrasound, Mymensingh during the period of July,

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Dr., Avinash Buche, Gauri Dank Dr., Vaishali Khadke Dr., and Sandhya Bhattad Dr. "Pregnancy Outcomes in Autoimmune Diseases." International Journal of Innovative Science and Research Technology 7, no. 7 (2022): 1289–92. https://doi.org/10.5281/zenodo.6997148.

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Autoimmune diseases are common in reproductive age group. Pregnancy is known to alter the disease course in many patients with autoimmune diseases.The aim of this study is to assess the impact of autoimmune connective tissue disorders and its treatment on the outcomes of pregnancy. Methods: 15 antenatal patients with autoimmune connective tissue diseases, comprising of Systemic Lupus Erythematosus (SLE), antiphospholipid antibody syndrome (APS), Undifferentiated Connective Tissue Diseases (UCTD), Rheumatoid Arthritis(RA),Sjogren’s syndrome, systemic sclerosis were analyzed with respect t

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Singh, Sandhya, C. Sathyavani, Rajnish Samal, Nirupama, and P. Hasna. "Hypertensive disorders of pregnancy in women with autoimmune disorders: A retrospective cohort study." Pregnancy Hypertension 36 (August 2024): 47–48. http://dx.doi.org/10.1016/j.preghy.2024.01.100.

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16

Bobrowski-Khoury, Natasha, Vincent T. Ramaekers, Jeffrey M. Sequeira, and Edward V. Quadros. "Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorders: Diagnosis, Treatment and Prevention." Journal of Personalized Medicine 11, no. 8 (2021): 710. http://dx.doi.org/10.3390/jpm11080710.

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Folate deficiency and folate receptor autoimmune disorder are major contributors to infertility, pregnancy related complications and abnormal fetal development including structural and functional abnormalities of the brain. Food fortification and prenatal folic acid supplementation has reduced the incidence of neural tube defect (NTD) pregnancies but is unlikely to prevent pregnancy-related complications in the presence of folate receptor autoantibodies (FRAb). In pregnancy, these autoantibodies can block folate transport to the fetus and in young children, folate transport to the brain. These

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Idler, Jay, Onur Turkoglu, Kara Patek, et al. "Neurocutaneous Disorders in Pregnancy." Obstetrical & Gynecological Survey 78, no. 10 (2023): 606–19. http://dx.doi.org/10.1097/ogx.0000000000001202.

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Importance Neurocutaneous disorders have significant implications for care of the pregnant patient. As neurocutaneous disorders are uncommon, obstetricians may be unfamiliar with these disorders and with recommendations for appropriate care of this population. Objective This review aims to summarize existing literature on the interaction between neurocutaneous disorders and pregnancy and to provide a guide for physicians caring for an affected patient. Evidence Acquisition A PubMed, MEDLINE, and Google Scholar search was carried out with a broad range of combinations of the medical subject hea

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18

Gerald J. Mizejewski. "Alpha-fetoprotein: Immunomodulation in autoimmune diseases during pregnancy and puerperium stages." GSC Biological and Pharmaceutical Sciences 20, no. 2 (2022): 102–13. http://dx.doi.org/10.30574/gscbps.2022.20.2.0268.

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Alpha-fetoprotein (AFP) has long been associated with regulation and modulation of the immune system in a variety of mammals. In the last several decades, AFP has been linked to autoimmune diseases (ADs) during both pregnancy and in non-gestational disorders via an immunomodulatory function. The course of ADs are highly influenced by soluble factors such as cytokines, chemokines, interleukins, hormones, kinins, growth factors, proteins such as AFP, and various T-cells generated from the immune response. Such factors appear to serve as protective or ameliorating agents during the induction effe

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Gerald, J. Mizejewski. "Alpha-fetoprotein: Immunomodulation in autoimmune diseases during pregnancy and puerperium stages." GSC Biological and Pharmaceutical Sciences 20, no. 2 (2022): 102–13. https://doi.org/10.5281/zenodo.7139531.

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Alpha-fetoprotein (AFP) has long been associated with regulation and modulation of the immune system in a variety of mammals. In the last several decades, AFP has been linked to autoimmune diseases (ADs) during both pregnancy and in non-gestational disorders via an immunomodulatory function. The course of ADs are highly influenced by soluble factors such as cytokines, chemokines, interleukins, hormones, kinins, growth factors, proteins such as AFP, and various T-cells generated from the immune response. Such factors appear to serve as protective or ameliorating agents during the induction effe

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20

Kowitz, Monique, Katrina Chakradeo, Ashleigh Hennessey, and Penny Wolski. "Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages." BMJ Case Reports 14, no. 5 (2021): e240929. http://dx.doi.org/10.1136/bcr-2020-240929.

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Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheumatological disorders in general can contribute to multiple pregnancy complications, very little is known about how anti-SS itself affects pregnancy outcomes. Described here is the case of a 26-year-old pregnant woman with anti-SS whose pregnancy course was complicated by placental dysfunction and sub

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21

Jankowska, Katarzyna, Piotr Dudek, Małgorzata Stasiek, and Katarzyna Suchta. "Autoimmune polyendocrine syndromes associated with autoimmune rheumatic diseases." Rheumatology 61, no. 4 (2023): 225–38. http://dx.doi.org/10.5114/reum/170266.

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Autoimmune polyendocrine syndromes (APSs), also called autoimmune polyglandular syndromes, are a group of autoimmune diseases characterized by the co-occurrence of dysfunctions of several (at least two) endocrine glands. They develop under the influence of environmental factors in genetically predisposed people. Autoimmune polyendocrine syndromes may accompany autoimmune rheumatic diseases and worsen their course – APS-2 and APS-3 are the most common. The APS-2 includes the coexistence of, e.g. Hashimoto’s disease, celiac disease and rheumatoid arthritis (RA). In APS-3, rheumatic diseases such

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Centanni, Marco, and Camilla Virili. "Pregnancy Outcome in Poly-Autoimmune Disorders: The Case of APECED Syndrome." Journal of Clinical Endocrinology & Metabolism 107, no. 4 (2021): e1754-e1755. http://dx.doi.org/10.1210/clinem/dgab783.

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23

Bogović Crnčić, Tatjana, Neva Girotto, Maja Ilić Tomaš, et al. "Innate Immunity in Autoimmune Thyroid Disease during Pregnancy." International Journal of Molecular Sciences 24, no. 20 (2023): 15442. http://dx.doi.org/10.3390/ijms242015442.

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Autoimmune thyroid disease (AITD) is the most common organ-specific autoimmune disorder clinically presented as Hashimoto thyroiditis (HT) and Graves’ disease (GD). The pathogenesis of AITD is caused by an inappropriate immune response related to genetic, non-genetic, and environmental factors. Pregnancy is one of the factors that have a great influence on the function of the thyroid gland because of the increased metabolic demand and the effects of hormones related to pregnancy. During pregnancy, an adaptation of the maternal immune system occurs, especially of the innate immune system engage

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Ağar, Mehmet, Belgin Devranoğlu, and Halime Çalı Öztürk. "Does autoimmune disease affect in vitro fertilization results in normo-responder cases?" Journal of Controversies in Obstetrics & Gynecology and Pediatrics 2, no. 1 (2024): 19–23. http://dx.doi.org/10.51271/jcogp-0028.

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Aims: This study aimed to assess the effects of autoimmune disorders on pregnancy outcomes in infertile women undergoing in vitro fertilization (IVF) treatment. Methods: This retrospective cohort study was conducted between March 2022 and September 2023, involving 90 infertile women without autoimmune diseases as a control group and 96 infertile women with autoimmune diseases as a case group. The study investigated the impact of autoimmune diseases on IVF treatment outcomes. Single embryo transfer (ET) was performed on the fifth day in all patients. Autoimmune diseases included in this study a

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Anandappa, Samantha, Mamta Joshi, Lukasz Polanski, and Paul V. Carroll. "Thyroid disorders in subfertility and early pregnancy." Therapeutic Advances in Endocrinology and Metabolism 11 (January 2020): 204201882094585. http://dx.doi.org/10.1177/2042018820945855.

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Disorders of thyroid function are common in pregnancy and have implications for foetal and maternal health. Thyroid autoimmunity, as evidenced by the presence of elevated levels of anti-thyroid antibodies (anti-TPO and anti-Tg antibodies) is associated with an increased risk of miscarriage, though the mechanism remains poorly understood. There has been considerable focus on the implications and optimal management of pregnant women with thyroid disease, especially those undergoing assisted reproduction. Pregnancy results in significant changes in thyroid physiology and these need to be understo

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Bedi, Mini, Sandeep Kaur, Prashant Patil, Kamaljeet Kaur, Harbhajan Kaur, and Harkiran Kaur. "Diverse presentation of connective tissue disorders in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 4 (2021): 1681. http://dx.doi.org/10.18203/2320-1770.ijrcog20211158.

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Connective tissue disorders (CTD) include a variety of chronic multisystem disorders including autoimmune conditions. Many of these conditions affect women of childbearing age and therefore pregnancy poses an important challenge for the caregivers. The precise knowledge of therapeutic safety and the effect of disease on pregnancy and vice versa are important to achieve best outcome. Hence, it is imperative to have a vast knowledge of disease with proper preconception counselling. We report series of cases of connective tissue disorders in pregnancy: tuberous sclerosis (TS), systemic lupus eryt

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Dr., Prajkta Anuse*1 &. Dr. Uma Wankhede2. "MULTIPLE AUTOIMMUNE DISEASES DIAGNOSED IN PREGNANCY: A CASE REPORT AND REVIEW OF MANAGEMENT." International Journal of Medical Research and Pharmaceutical Sciences 5, no. 2 (2018): 15–20. https://doi.org/10.5281/zenodo.1172917.

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Multiple autoimmune diseases is association of immunological disorders. It represent the best example of polyautoimmunity. Vitiligo, characterized by destruction of melanocytes, causes a patchy depigmentation of the skin. It has been hypothesized to have an autoimmune pathogenesis. The autoimmune nature of most thyroid disease is important in the course of the illness during pregnancy and fetal consequences because of the association of thyroid antibodies with particular obstetric outcomes and the effect of pregnancy onantibody titers. Immune (idiopathic) thrombocytopenic purpura (ITP) is an u

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Naha, Sowjanya, Joseph Theressa Nehu Parimi, Rajani Gundluru, John Chen Liu, Hasan Syed, and Timur Gusov. "Persistent Fatigue After Pregnancy: A Case Report." Journal of the Endocrine Society 5, Supplement_1 (2021): A147. http://dx.doi.org/10.1210/jendso/bvab048.297.

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Abstract Background: Pregnancy is characterized by physiologic immunosuppression and the postpartum period is often associated with rebound autoimmunity leading to unmasking of latent autoimmune disorders. Clinical Case: A thirty-one-year-old Caucasian female presented with generalized fatigue, myalgias and arthralgias that started three months after the birth of her first child. She was seen at a local hospital on multiple occasions and was treated symptomatically. She was noted to have orthostatic hypotension during these visits and was initiated on midodrine and fludrocortisone for presumed

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Saad, AF, LD Pacheco, and GR Saade. "Immunosuppressant Medications in Pregnancy." Obstetric Anesthesia Digest 44, no. 3 (2024): 120–21. http://dx.doi.org/10.1097/01.aoa.0001026504.06583.94.

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(Obstet Gynecol. 2024;143(4):e94–e106. doi: 10.1097/AOG,0000000000005512) Pregnant patients often take immunosuppressant medications for solid organ transplant rejection prevention or autoimmune disorders. It is important that they adhere to prescribed regimens before and during pregnancy to avoid serious consequences. Close monitoring of organ function, signs of rejection, and immunosuppressant levels are vital. Counseling for reproductive patients should include discussions on how pregnancy may impact their condition, potential fetal effects of medications, and breastfeeding considerations.

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Sadykova, G. K., and A. A. Olina. "The role of selenium deficiency in the development of thyroid dysfunction during pregnancy (literature review)." Medical Science And Education Of Ural 21, no. 4 (2020): 159–63. http://dx.doi.org/10.36361/1814-8999-2020-21-4-159-163.

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The article presents generalized data on the influence of nutritional quality on the risk of developing gestational disorders, as well as the development of dysfunctional thyroid diseases associated with pregnancy. The role of selenium deficiency in the genesis of such pregnancy complications as preeclampsia, premature birth, as well as autoimmune thyroiditis, hypothyroidism and insulin resistance is considered. The necessity of subsidizing selenium preparations during pregnancy as a measure of preventing the development of these conditions is discussed.

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Lee, L. H. "Idiopathic Thrombocytopenia in Pregnancy." Annals of the Academy of Medicine, Singapore 31, no. 3 (2002): 335–39. https://doi.org/10.47102/annals-acadmedsg.v31n3p335.

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Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder in which antiplatelet autoantibodies bind to the antigens on platelet surfaces, resulting in their destruction. It is one of the most common autoimmune disorders that physicians manage today. Although it can present itself at any age, it tends to occur in young women. Hence, it commonly affects women in the childbearing age group. It is a haematological disorder for which diagnostic and treatment strategies are not well defined. In the past decade, there have been attempts for consensus in the management of patients with ITP,

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Braunstein, Inbal, and Victoria Werth. "Treatment of dermatologic connective tissue disease and autoimmune blistering disorders in pregnancy." Dermatologic Therapy 26, no. 4 (2013): 354–63. http://dx.doi.org/10.1111/dth.12076.

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Mladenovic, Violeta, Ravi Shah, Sanja Medenica, et al. "Thyroid Gland and Pregnancy – Clinical Update." Hormone and Metabolic Research 57, no. 05 (2025): 303–14. https://doi.org/10.1055/a-2604-4177.

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AbstractThyroid function undergoes significant alterations during pregnancy due to changes in hormone levels and higher metabolic demands. The thyroid gland in pregnancy enlarges by 10%; however, in iodine-deficient areas, this growth might reach 40%. Elevated levels of human chorionic gonadotropin (hCG) in early pregnancy leads to increased thyroid hormone production. While triiodothyronine (T3) and thyroid-stimulating hormone (TSH) do not cross the placenta, thyroxine (T4) does. Thyroid hormone demands peaks between weeks 16 and 20 of pregnancy and remains high until delivery. There is a ris

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Kauloorkar, Bhoomika Madhukar, Beatrice Anne, Amritava Ghosh, Rajesh Rajput, Krishna Seshadri, and Soumik Goswami. "Navigating thyroid disorders in pregnancy: Minutes of the special symposium of ESICON 2023." Thyroid Research and Practice 20, no. 3 (2024): 99–104. https://doi.org/10.4103/trp.trp_8_24.

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Thyroid disorders are among the most common endocrine conditions that can affect pregnancy. Maternal thyroid dysfunction, including both hypothyroidism and hyperthyroidism, can significantly impact pregnancy outcomes and fetal development. Thyroid hormone regulation is crucial for normal fetal brain development, particularly during the first trimester when the fetus is entirely dependent on maternal thyroid hormones. This review aims to provide an overview of the physiological changes in thyroid function during pregnancy, discuss common thyroid disorders, their diagnosis, and management strate

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Urakov, Jamshid Rustamovich. "PATHOLOGY OF THE THYROID GLAND IN PATIENTS WITH RHEUMATOID ARTHRITIS." Multidisciplinary Journal of Science and Technology 4, no. 6 (2024): 553–56. https://doi.org/10.5281/zenodo.12549917.

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Endocrine disorders are of significant importance in the occurrence and progression of rheumatic diseases. Often, endocrine changes that occur during puberty, menopause, pregnancy, childbirth, and abortion serve as a background for the development of connective tissue diseases [6, 13]. At the same time, changes in neuroendocrine status are an integral component of the progression of rheumatic diseases [2, 5, 14].

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Nemesánszky, Elemér. "Unfavourable laboratory results and hepatic disorders in pregnancy: causes and consequences." Orvosi Hetilap 154, no. 29 (2013): 1135–41. http://dx.doi.org/10.1556/oh.2013.29635.

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The well-known normal ranges of laboratory parameters are altered due to the broad spectrum of physiological changes as well as proinflammatory and procoagulant effects of pregnancy. Hepatic disorders of any aetiology can cause potential problems during gravidity. Most frequently toxic-effects, hepatotrop viruses (such as hepatitis B and C), metabolic syndrome and diseases with autoimmune background can be observed. When dealing with “pregnancy-specific hepatic syndromes”, it is very important to consider the „timing-factors” of pathologic changes and deterioration of clinical pictures as well

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Zengin, Erkam, Irina Kharisova, Dokpe Emechebe, and Yaacov Anziska. "Concurrent NMDAR and GFAP Antibody Encephalitis During Pregnancy." BMJ Case Reports 16, no. 7 (2023): e250998. http://dx.doi.org/10.1136/bcr-2022-250998.

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Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune antibody encephalitis, commonly affecting young women with comorbid ovarian teratoma. It typically presents with alteration of consciousness, psychosis, movement disorders eventually deteriorating with seizures, dysautonomia and central hypoventilation requiring critical level of care that may last weeks to months. Removal of teratoma and immunosuppressant therapy support can led to a dramatic recovery.To our knowledge, this is the first illustrated case in the literature of a pregnant woman presenting with concurrent aut

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Likic-Ladjevic, Ivana, Milos Petronijevic, Svetlana Vrzic-Petronijevic, and Aleksandra Beleslin. "A rare case of alpha-methyldopa-induced hepatitis in pregnancy." Srpski arhiv za celokupno lekarstvo, no. 00 (2024): 4. http://dx.doi.org/10.2298/sarh231107004l.

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Introduction. There are three groups of disorders during pregnancy: disorders specific for pregnancy that resolve spontaneously or soon after delivery, acute hepatic disorders coinciding with pregnancy and chronic disorders. Drug-induced liver disease prevails among women and it is estimated to be a leading cause of acute liver injury. Drug-induced hepatitis is rare in pregnancy with only a few cases reported in the literature. Alpha-methyldopa is one of the commonly used drugs in pregnancy that could cause hepatotoxicity with different clinical presentations and possible adverse effects on no

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Geetha, Karra, G. Sasanka, S. Pridvineel, Meraj Unnisa Banu, and T. Rama Rao. "A Review on Hashimoto’s Thyroiditis." Journal of Drug Delivery and Therapeutics 13, no. 12 (2023): 250–54. http://dx.doi.org/10.22270/jddt.v13i12.6133.

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Hashimoto's thyroiditis (HT) is an autoimmune thyroid disorder first described by Japanese physician Haraku Hashimoto in 1912 characterized by lymphocytic infiltration of the thyroid parenchyma and is influenced by immune system instability. The onset of autoimmunity may be influenced by innate and acquired immune responses. Thyroid autoantibodies (TAbs) are the primary biochemical feature. Epidemiological studies show AITD (autoimmune thyroid disease) risk is higher in women and is age-related. Risk factors include high iodine consumption, selenium insufficiency, infectious disorders, and spe

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Baker, Jessica, and Albert Hung. "Movement Disorders in Women." Seminars in Neurology 37, no. 06 (2017): 653–60. http://dx.doi.org/10.1055/s-0037-1608845.

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AbstractMovement disorders such as Parkinson's disease (PD), restless legs syndrome (RLS), chorea, essential tremor, and Tourette syndrome, occur in men and women of all ages. Yet, considerable sex differences in epidemiology, clinical features, and treatment exist in these disorders. In this review, we highlight key differences in the evaluation and management of women with movement disorders, addressing sex-specific complications of treatment and unique challenges surrounding the management of movement disorders during pregnancy. We review the complex relationship between estrogen and moveme

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Reisz, Daniela, Iulia-Gabriela Gramescu, Stefan Mihaicuta, Florina Georgeta Popescu, and Doina Georgescu. "NMDA Autoimmune Encephalitis and Severe Persistent Hypokalemia in a Pregnant Woman." Brain Sciences 12, no. 2 (2022): 221. http://dx.doi.org/10.3390/brainsci12020221.

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Introduction: For more than a decade, NMDAR autoimmune encephalitis has been studied and treated as a neurological condition, and good results have been achieve through immune therapies. Apart from being well represented in the CNS, NMDA receptors are currently known of and being studied in multiple non-neuronal cells with potential clinical significance. The association of NMDAR autoimmune encephalitis with pregnancy is rare, and hypokalemia is not mentioned. Methods: We present the case of a 30-year-old woman with NMDAR autoimmune encephalitis in her 17th week of pregnancy associated with pe

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Fetene, Dagnachew Muluye, Kim S. Betts, and Rosa Alati. "MECHANISMS IN ENDOCRINOLOGY: Maternal thyroid dysfunction during pregnancy and behavioural and psychiatric disorders of children: a systematic review." European Journal of Endocrinology 177, no. 5 (2017): R261—R273. http://dx.doi.org/10.1530/eje-16-0860.

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Background Maternal thyroid dysfunction during pregnancy may lead to persistent neurodevelopmental disorders in the offspring appearing in later life. This study aimed to review the available evidence concerning the relationship between maternal thyroid status during pregnancy and offspring behavioural and psychiatric disorders. Methods Systematic electronic database searches were conducted using PubMed, Embase, PsycNET, Scopus, Google Scholar and Cochrane library. Studies including gestational thyroid dysfunction as the exposure and offspring behavioural and psychiatric disorders as the outco

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Moustakli, Efthalia, Sofoklis Stavros, Theologos M. Michaelidis, et al. "Long-Term Effects of COVID-19 on Women’s Reproductive Health and Its Association with Autoimmune Diseases, Including Multiple Sclerosis." Journal of Clinical Medicine 14, no. 9 (2025): 3057. https://doi.org/10.3390/jcm14093057.

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Concern over COVID-19’s long-term influence on women’s reproductive health is growing, with emerging research suggesting potential links to ovarian dysfunction, menstrual irregularities, fertility challenges, and adverse pregnancy outcomes. Post-viral immune dysregulation is linked to both the development and exacerbation of autoimmune diseases, including multiple sclerosis (MS). Long COVID has been associated with immunological dysfunction, hormonal imbalances, and chronic inflammation, all of which may worsen autoimmune disorders and reproductive health issues. Long COVID is characterized by

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Medenica, Sanja, Dzihan Abazovic, Aleksandar Ljubić, et al. "The Role of Cell and Gene Therapies in the Treatment of Infertility in Patients with Thyroid Autoimmunity." International Journal of Endocrinology 2022 (August 30, 2022): 1–10. http://dx.doi.org/10.1155/2022/4842316.

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There is a rising incidence of infertility worldwide, and many couples experience difficulties conceiving nowadays. Thyroid autoimmunity (TAI) is recognized as one of the major female infertility causes related to a diminished ovarian reserve and potentially impaired oocyte maturation and embryo development, causing adverse pregnancy outcomes. Growing evidence has highlighted its impact on spontaneously achieved pregnancy and pregnancy achieved by in vitro fertilization. Despite the influence of thyroid hormones on the male reproductive system, there is insufficient data on the association bet

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Kolenko, O. V., E. L. Sorokin, N. S. Khodzhaev, et al. "Role of Gestational Hypertension and Preeclampsia as Risk Factors for Formation of Vascular Disorders of Retina in Remote Period after Delivery." Ophthalmology in Russia 17, no. 3 (2020): 389–97. http://dx.doi.org/10.18008/1816-5095-2020-3-389-397.

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Purpose. To study the correlation between pregnancy, complicated by preeclampsia and gestational hypertension (GH), and formation of retinal vascular and optic nerve disorders in the late postpartum period.Patients and methods. 231 women with different previous pregnancy variants of pathology. Exclusion criteria — presence of systemic endocrine, autoimmune, rheumatic pathology before pregnancy; bad habits. Four groups were formed. 1st main group: pregnancy with GH. 2nd main group: pregnancy with preeclampsia. 1st comparison group: pregnancy on the background of pre-existing hypertension, witho

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Fortunato, Francesca, Domenico Martinelli, Rosa Prato, and Biagio Pedalino. "Results fromAd Hocand Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011." Scientific World Journal 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/614269.

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Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15–49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata (Italy). Moreover, we selected hospital discharge records (HDRs) of celiac women and women with a

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J.F. Gurbanova, A.F. Amirova, and İ.İ. Huseynova. "The role of the immune state of the endometrium in the recurrent implantation disorders and miscarriages." Actual Questions of Modern Gynecology and Perinatology 12, no. 1 (2025): 9–16. https://doi.org/10.28942/mgpam.v12i1.158.

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The immune response is strongly affected by metabolic and nutritional parameters, inflammatory exposures and autoimmune conditions, and age. Inflammatory health conditions, including intestinal microbial dysbiosis, hyperglycemia, metabolicdysfunction, and dietary deficiencies, particularly vitamins A and D, can interfere with both innate and adaptive immunities and form readily tractable targets for infertility treatment. High-risk women with previous reproductive and pregnancy conditions are an obvious target for preconception care to boost immune function. Addressing these and related clinic

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Beneventi, Fausta, Elena Locatelli, Roberto Caporali, et al. "Connective tissue diseases and autoimmune thyroid disorders in the first trimester of pregnancy." Journal of Reproductive Immunology 114 (April 2016): 32–37. http://dx.doi.org/10.1016/j.jri.2016.02.004.

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AlJasser, Mohammed I., Chris Sladden, Richard I. Crawford, and Sheila Au. "Bullous Pemphigoid Associated with Acquired Hemophilia A: A Rare Association of Autoimmune Disease." Journal of Cutaneous Medicine and Surgery 18, no. 2 (2014): 123–26. http://dx.doi.org/10.2310/7750.2013.13060.

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Background: Acquired hemophilia (AH) is a rare autoimmune disease with an annual incidence of one per million and has a mortality rate of up to 22%. It is caused by the development of autoantibodies against factor VIII. Approximately half of the reported cases are associated with autoimmune disorders, pregnancy, malignancies, and adverse drug reactions. Autoimmune diseases are the most frequently associated disorders and include rheumatoid arthritis, systemic lupus erythematosus, cryoglobulinemia, pemphigus vulgaris, and bullous pemphigoid. There are a few reports of acquired hemophilia and bu

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NICA, Adriana, Ana Maria VLĂDĂREANU, Minodora ONISÂI, et al. "Management of a case of supra-acute immune thrombocytopenic purpura in pregnancy finalized with splenectomy." Romanian Journal of Medical Practice 10, no. 1 (2015): 73–78. http://dx.doi.org/10.37897/rjmp.2015.1.12.

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Splenectomy is a therapeutic procedure for a wide range of conditions, mainly hematological disorders. From the hematological disorders we can mention the red cell disorders: haemolytic anemia, hereditary spherocytosis and thalassemia, that have indication for splenectomy in case of failure to the drug treatment. A wide variety of thrombocytopenic disorders are improved by splenectomy, and the most common indicatios is for Idiopatic Thrombocitopenic Purpura (ITP). However, splenectomy imparts a high risk of fulminant infections that can be avoided with proper prophylaxis. Although in ITP splen

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