Relevant bibliographies by topics / Autoimmune pancreatitis, biomarker, diagnosis, plasmablasts

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Autoimmune pancreatitis, biomarker, diagnosis, plasmablasts'

Author: Grafiati
Published: 11 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Autoimmune pancreatitis, biomarker, diagnosis, plasmablasts"

1

Kawa, Shigeyuki, Tetsuya Ito, Takayuki Watanabe, et al. "The Utility of Serum IgG4 Concentrations as a Biomarker." International Journal of Rheumatology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/198314.

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IgG4-related disease is a new disease entity involving IgG4 in its clinical presentation and having 6 characteristic features: (1) systemic involvement; (2) solitary or multiple lesions showing diffuse or localized swelling, masses, nodules, and/or wall thickening on imaging; (3) high serum IgG4 concentration >135 mg/dL; (4) abundant infiltration of lymphoplasmacytes and IgG4-bearing plasma cells; (5) a positive response to corticosteroid therapy; and (6) complications of other IgG4-related diseases. To date, most IgG4-related diseases have been recognized as extrapancreatic lesions of auto
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2

Maritati, Federica, Francesco Peyronel, and Augusto Vaglio. "IgG4-related disease: a clinical perspective." Rheumatology 59, Supplement_3 (2020): iii123—iii131. http://dx.doi.org/10.1093/rheumatology/kez667.

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Abstract IgG4-related disease (IgG4-RD) is a recently recognized fibro-inflammatory disorder that can affect almost any organ. Common presentations include major salivary and lacrimal gland enlargement, orbital disease, autoimmune pancreatitis, retroperitoneal fibrosis and tubulointerstitial nephritis. The main histopathological features are a dense, polyclonal, lymphoplasmacytic infiltrate rich in IgG4+ plasma cells, storiform fibrosis and obliterative phlebitis. The precise pathogenic mechanisms of IgG4-RD are still unclear. CD4+ T and B cells, including IgG4-expressing plasmablasts, constit
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Dugic, Ana, Cristina Verdejo Gil, Claudia Mellenthin, Miroslav Vujasinovic, J. Matthias Löhr, and Steffen Mühldorfer. "The Clinical Utility of Soluble Serum Biomarkers in Autoimmune Pancreatitis: A Systematic Review." Biomedicines 10, no. 7 (2022): 1511. http://dx.doi.org/10.3390/biomedicines10071511.

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Autoimmune pancreatitis (AIP) is a rare etiological type of chronic pancreatitis. The clinical and radiological presentation of AIP often resembles that of pancreatic cancer. Identifying non-invasive markers for their early distinction is of utmost importance to avoid unnecessary surgery or a delay in steroid therapy. Thus, this systematic review was conducted to revisit all current evidence on the clinical utility of different serum biomarkers in diagnosing AIP, distinguishing AIP from pancreatic cancer, and predicting disease course, steroid therapy response, and relapse. A systematic review
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Hayashi, Kazunao, Atsunori Tsuchiya, and Shuji Terai. "Abstract B006: Exosomal protein Eps8 as a new biomarker for pancreatic cancer." Cancer Research 84, no. 2_Supplement (2024): B006. http://dx.doi.org/10.1158/1538-7445.panca2023-b006.

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Abstract Exosomes are extracellular vesicles containing nucleic acids, proteins, and lipids of approximately 100 nm, which are released from cancer cells to create a microenvironment favorable for their survival. Epidermal growth factor receptor pathway substrate 8 (Eps8), an exosomal protein, is reportedly associated with metastasis. We investigated the relationship between Eps8 in the serum exosomes of patients with pancreatic cancer and clinicopathological factors and examined the usefulness of exosomal Eps8 as a biomarker for pancreatic cancer. Methods: Serum exosomes of 93 patients with p
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Zhong, Jingyu, Yangfan Hu, Yue Xing, et al. "A systematic review of radiomics in pancreatitis: applying the evidence level rating tool for promoting clinical transferability." Insights into Imaging 13, no. 1 (2022). http://dx.doi.org/10.1186/s13244-022-01279-4.

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Abstract Background Multiple tools have been applied to radiomics evaluation, while evidence rating tools for this field are still lacking. This study aims to assess the quality of pancreatitis radiomics research and test the feasibility of the evidence level rating tool. Results Thirty studies were included after a systematic search of pancreatitis radiomics studies until February 28, 2022, via five databases. Twenty-four studies employed radiomics for diagnostic purposes. The mean ± standard deviation of the adherence rate was 38.3 ± 13.3%, 61.3 ± 11.9%, and 37.1 ± 27.2% for the Radiomics Qu
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6

Beuers, Ulrich, and David C. Trampert. "IgG4-Related Cholangitis." Seminars in Liver Disease, May 8, 2025. https://doi.org/10.1055/a-2588-3875.

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IgG4-related cholangitis (IRC) is a rare fibroinflammatory disease of the biliary tree and liver and presents the major hepatobiliary manifestation of IgG4-related systemic disease (IgG4-RD). IRC also includes the IgG4-related inflammatory pseudotumor of the liver and IgG4-related cholecystitis. IRC mimics other cholangiopathies such as primary sclerosing cholangitis or cholangiocarcinoma. IRC may be found in 30 to 60% of cases with type 1 autoimmune pancreatitis, the most frequent manifestation of IgG4-RD. The pathogenesis of IRC (and IgG4-RD) is incompletely understood. Genetic predispositio
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7

Chen, Si, Hanlei Zhang, Fang Fang, Chao Ye, and Kaiguang Zhang. "Characteristics of mass-forming autoimmune pancreatitis commonly misdiagnosed as a malignant tumor." Frontiers in Surgery 10 (January 25, 2023). http://dx.doi.org/10.3389/fsurg.2023.1017621.

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ObjectiveThis study aimed to explore the clinical characteristics and differential diagnosis of patients with autoimmune pancreatitis (AIP) and pancreatic cancer to prevent misdiagnosis and mistreatment.MethodsThe clinical data of patients with AIP with suspected pancreatic or bile duct malignancy and pancreatic cancer were retrospectively analyzed. The risk factors and the diagnostic value of IgG4 and Tbil levels before treatment for AIP was investigated. Moreover, the imaging features and response to hormone therapy were analyzed.ResultsAIP was commonly observed in men. Compared to patients
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8

Byrling, J., K. S. Hilmersson, D. Ansari, R. Andersson, and B. Andersson. "Thrombospondin-2 as a diagnostic biomarker for distal cholangiocarcinoma and pancreatic ductal adenocarcinoma." Clinical and Translational Oncology, July 28, 2021. http://dx.doi.org/10.1007/s12094-021-02685-8.

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Abstract Purpose Distal cholangiocarcinoma and pancreatic ductal adenocarcinoma are malignancies with poor prognoses that can be difficult to distinguish preoperatively. Thrombospondin-2 has been proposed as a novel diagnostic biomarker for early pancreatic ductal adenocarcinoma. The aim of the present study was to evaluate thrombospondin-2 as a diagnostic and prognostic biomarker in combination with current biomarker CA 19-9 for distal cholangiocarcinoma and pancreatic ductal adenocarcinoma. Methods Thrombospondin-2 was measured in prospectively collected serum samples from patients who under
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Dissertations / Theses on the topic "Autoimmune pancreatitis, biomarker, diagnosis, plasmablasts"

1

Marchi, Giulia De. "Circulating total and IgG4+ plasmablasts for the diagnosis of type 1 Autoimmune Pancreatitis." Doctoral thesis, 2022. http://hdl.handle.net/11562/1058575.

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OBIETTIVI: La pancreatite autoimmune (AIP) di tipo 1 rappresenta una possibile manifestazione della malattia IgG4-relata (IgG4-RD), la cui diagnosi è a volte ancora difficile da formulare. I plasmablasti circolanti sono stati proposti come possibile marcatore sierico sensibile e specifico, anche se non è chiaro se possano differenziare tra AIP di tipo 1, di tipo 2 e altre condizioni pancreatiche. Obiettivo dello studio è stato valutare il valore diagnostico dei livelli di plasmablasti totali e di IgG4+ circolanti nell'AIP e in altre malattie del pancreas. METODI: Sono stati arruolati prospetti
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