Dissertations / Theses on the topic 'Automated design synthesis'
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Hwang, Yves. "An automated software design synthesis framework." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0157.
Full textNastov, Ognen J. (Ognen Jovan). "Automated design synthesis of CMOS operational amplifers." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/36432.
Full textThomas, Dale Arlington III. "Design and implementation of an automated reconfigurable modular flow chemistry synthesis platform." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/121851.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (pages 115-124).
Synthetic chemistry has been the driving force behind advances in pharmaceuticals, agricultural chemicals to advanced materials; however, these fields have struggled with a slow pace of discovery, limited reproducibility, and difficulty scaling promising new molecules. Current organic chemistry labs rely on batch methodologies limiting the safe process windows, contributing to scaling difficulties, and causing reproducibility issues. Advances in laboratory automation and flow chemistry can be combined to address this bottleneck while increasing expert chemists' productivity. Automated reaction platforms, however, have been limited in their ability to access a diverse set of process units, beyond simple mixing and stirring. A system capable of carrying out multi-step syntheses, inline reaction monitoring, multi-phase reactions, and is easily reconfigurable could enable access to novel process windows and enhance laboratory productivity.
In this work, the development of a reconfigurable continuous flow chemistry platform capable of multistep syntheses is undertaken. This system is capable of interfacing with a library of process modules capable of handling solids, aggressive reagents, inline separations, and reaction conditions required for organic synthesis. These modules can be reconfigured and connected into the required sequence for target molecule synthesis. With reagents being routed to the process modules through the physical wiring of the connections to the assembled process modules eliminating complex valving manifolds. The assembly of the system is coordinated through graphical user interfaces (GUI) which executes a user generated recipe. The platform has been used to rapidly synthesize a variety of active pharmaceutical ingredients (API) and dyes requiring stereo-selectivity, site-selectivity, library generation, and convergent synthesis.
This integrated reconfigurable flow chemistry platform aims to decrease the time required for synthesizing new molecules while increasing synthetic repeatability and lab-to-lab transferability. Automation of synthetic chemistry can decrease the time for molecule development and allow chemists to focus on pathway refinement, reaction optimization, and process analytics. This work required the incorporation of design concepts from microfluidics, robotics, and precision machine design into an integrated modular system for continuous end-to-end production of molecules.
by Dale Arlington Thomas III.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Mechanical Engineering
Zhang, Haoqi. "Computational Environment Design." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10598.
Full textEngineering and Applied Sciences
Deas, Alexander Roger. "An idiomatic framework for the automated synthesis of topographical information from behavioural specifications." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/13604.
Full textRANJAN, MUKESH. "AUTOMATED LAYOUT-INCLUSIVE SYNTHESIS OF ANALOG CIRCUITS USING SYMBOLIC PERFORMANCE MODELS." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1129922496.
Full textSvahn, Carl. "Quantified Interactive Morphological Matrix : An automated approach to aircraft fuel system synthesis." Thesis, Linköping University, Department of Mechanical Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7715.
Full textThis report is one part of a masters thesis in mechanical engineeing. Is is executed at the Department of Mechanical Engineering at Linköping Insitute of Technology in cooperation with Saab Aerosystems in Linköping.
A tool for concept generation called a quantified interactive morphological matrix has been created. It is based on rules of thumb and approximations concerning aircraft fuel systems.
The tool can be used for discarding bad concepts, with regard to weight, power consumption and MTBF, during the concept phase of a fuel system design process. The tool is ready for calibration towards a future specific area of use. It is open for validation and optimization and is specifically designed to be easily modified for different future products.
Suggestions for future use has been given concerning expansion, implementation, validation and optimization.
Das, Angan. "Algorithms for Topology Synthesis of Analog Circuits." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1227204301.
Full textJin, Zengxiang. "An automated size synthesis system for preliminary design of tall buildings under both vertical and lateral loads /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?CIVL%202002%20JIN.
Full textIncludes bibliographical references (leaves 125-128). Also available in electronic version. Access restricted to campus users.
KANKIPATI, SUNDER RAJAN. "MACRO MODEL GENERATION FOR SYNTHESIS OF ANALOG AND MIXED SIGNAL CIRCUITS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1077297705.
Full textShin, Eung Seo. "Automated Generation of Round-robin Arbitration and Crossbar Switch Logic." Diss., Available online, Georgia Institute of Technology, (2003), 2003. http://etd.gatech.edu/theses/available/etd-11232003-150424/.
Full textBeikzadeh, Mohammad Reza. "Automatic high-level synthesis based upon artificial intelligence techniques." Thesis, University of Essex, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315691.
Full textCarrera, Montesinos Javier. "AUTOMATIC COMPUTATIONAL DESIGN OF SYNTHETIC GENOMES." Doctoral thesis, Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/35380.
Full textCarrera Montesinos, J. (2012). AUTOMATIC COMPUTATIONAL DESIGN OF SYNTHETIC GENOMES [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/35380
Palancia
TAKADA, Hiroaki, Hiroyuki TOMIYAMA, Shinya HONDA, Seiya SHIBATA, and Yuki ANDO. "Automatic Communication Synthesis with Hardware Sharing for Multi-Processor SoC Design." Institute of Electronics, Information and Communication Engineers, 2010. http://hdl.handle.net/2237/15033.
Full textMutigwe, Charles. "Automatic synthesis of application-specific processors." Thesis, Bloemfontein : Central University of Technology, Free State, 2012. http://hdl.handle.net/11462/163.
Full textThis thesis describes a method for the automatic generation of appli- cation speci_c processors. The thesis was organized into three sepa- rate but interrelated studies, which together provide: a justi_cation for the method used, a theory that supports the method, and a soft- ware application that realizes the method. The _rst study looked at how modern day microprocessors utilize their hardware resources and it proposed a metric, called core density, for measuring the utilization rate. The core density is a function of the microprocessor's instruction set and the application scheduled to run on that microprocessor. This study concluded that modern day microprocessors use their resources very ine_ciently and proposed the use of subset processors to exe- cute the same applications more e_ciently. The second study sought to provide a theoretical framework for the use of subset processors by developing a generic formal model of computer architecture. To demonstrate the model's versatility, it was used to describe a number of computer architecture components and entire computing systems. The third study describes the development of a set of software tools that enable the automatic generation of application speci_c proces- sors. The FiT toolkit automatically generates a unique Hardware Description Language (HDL) description of a processor based on an application binary _le and a parameterizable template of a generic mi- croprocessor. Area-optimized and performance-optimized custom soft processors were generated using the FiT toolkit and the utilization of the hardware resources by the custom soft processors was character- ized. The FiT toolkit was combined with an ANSI C compiler and a third-party tool for programming _eld-programmable gate arrays (FPGAs) to create an unconstrained C-to-silicon compiler.
Pouya, Bahram. "Synthesis of testable core-based designs /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.
Full textMANSOURI, NAZANIN. "AUTOMATED CORRECTNESS CONDITION GENERATION FOR FORMAL VERIFICATION OF SYNTHESIZED RTL DESIGNS." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin982064542.
Full textTakada, Hiroaki, Hiroyuki Tomiyama, Shinya Honda, Seiya Shibata, and Yuki Ando. "Automatic Communication Synthesis with Hardware Sharing for Design Space Exploration." IEEE, 2010. http://hdl.handle.net/2237/14472.
Full textAndersson, Sofie. "Automatic Control Design Synthesis under Metric Interval Temporal Logic Specifications." Thesis, KTH, Skolan för elektro- och systemteknik (EES), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-187716.
Full textProblemet gällande regulator syntetisering for rörelse planering av fler-agents system under Line-ar Temporal Logic (Linjär Temporal Logik=LTL) hög-nivå specifikationer har varit av stort intresse och har studerats brett under de senaste åren. LTL kan emellertid inte hantera tidsbegränsningar som specifikationer. Tidsaspekten skulle tillåta mer komplicerade och specifika uppgifter. Det är därför önskvärt att inkorporera. Målet med det här arbetet är att fastställa hur regulator syntetisering för ett kontinuerligt, linjärt system kan utföras utgående från Metric Interval Temporal Logic (Metrisk Intervall Temporal Logic =MITL), en gren av Temporal Logik som kan hantera de önskvärda tidsbegränsningarna för högnivå specifikationer. Först presenteras en metod för att syntetisera regulatorer för en-agents system. Metoden är baserad på tidigare arbeten inom fälten LTL och MITL. Sedan presenteras en metod för att syntetisera regulatorer för fler-agents system som ¨önskas uppfylla såväl lokala som globala MITL specifikationer. Utbredda simulationer har genomförts i MATLAB miljö för att demonstrera de två˚ föreslagna metoderna. Resultatet visar att metoderna garanterar att MITL specifikationerna är uppfyllda för alla fall för vilka en lösning hittas.
Nixon, Ian Michael. "The automatic synthesis of fault tolerant and fault secure VLSI systems." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/6637.
Full textSoulat, Romain. "Synthesis of correct-by-design schedulers for hybrid systems." Phd thesis, École normale supérieure de Cachan - ENS Cachan, 2014. http://tel.archives-ouvertes.fr/tel-01062337.
Full textRichards, Daniel. "Automatic synthesis of architectural structures using an evo-devo approach to design." Thesis, Manchester Metropolitan University, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582532.
Full textSinghal, Rahul. "Logic Realization Using Regular Structures in Quantum-Dot Cellular Automata (QCA)." PDXScholar, 2011. https://pdxscholar.library.pdx.edu/open_access_etds/196.
Full textUngureanu, George. "Automatic Software Synthesis from High-Level ForSyDe Models Targeting Massively Parallel Processors." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-127832.
Full textWilliams, Robert L. "Synthesis and design of the RSSR spatial mechanism for function generation." Thesis, Virginia Tech, 1985. http://hdl.handle.net/10919/41573.
Full textThe purpose of this thesis is to provide a complete package for the synthesis and design of the RSSR spatial function generating mechanism.
In addition to the introductory material this thesis is divided into three sections. The section on background kinematic theory includes synthesis, analysis, link rotatability, transmission quality, and branching analysis. The second division details the computer application of the kinematic theory. The program RSSRSD has been developed to incorporate the RSSR synthesis and design theory. An example is included to demonstrate the computer-implemented theory.
The third part of this thesis includes miscellaneous mechanism considerations and recommendations for further research.The theoretical work in this project is a combination of original derivations and applications of the theory in the mechanism literature.
Master of Science
Slezák, Josef. "Evoluční syntéza analogových elektronických obvodů s využitím algoritmů EDA." Doctoral thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-233666.
Full textThapliyal, Himanshu. "Design, Synthesis and Test of Reversible Circuits for Emerging Nanotechnologies." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3379.
Full textDing, Huafeng [Verfasser], and Andrés [Akademischer Betreuer] Kecskeméthy. "Automatic Structural Synthesis of Planar Mechanisms and Its Application to Creative Design / Huafeng Ding. Betreuer: Andrés Kecskeméthy." Duisburg, 2016. http://d-nb.info/108130300X/34.
Full textAnkelhed, Daniel. "On design of low order H-infinity controllers." Doctoral thesis, Linköpings universitet, Reglerteknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-67869.
Full textChou, Pang-Yen [Verfasser]. "Automatic Analog Layout Synthesis – from Capacitor Arrays in Data Converters to General Design with Routing / Pang-Yen Chou." München : Verlag Dr. Hut, 2021. http://d-nb.info/123284666X/34.
Full textGmeiner, Thomas [Verfasser], Kristina [Akademischer Betreuer] Shea, Udo [Akademischer Betreuer] Lindemann, and Farhad [Akademischer Betreuer] Ameri. "Automatic Fixture Design Based on Formal Knowledge Representation, Design Synthesis and Verification / Thomas Gmeiner. Betreuer: Kristina Shea. Gutachter: Udo Lindemann ; Kristina Shea ; Farhad Ameri." München : Universitätsbibliothek der TU München, 2015. http://d-nb.info/1077867352/34.
Full textVoitovich, Iuliia. "Les inhibiteurs d'interaction protéine-protéine, une stratégie innovante en cancérologie." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0701.
Full textBET-proteins, acting as epigenetic readers, play an essential role in cancer development. To date, numerous potent inhibitors disrupting BET functions have been discovered, including several of them that are undergoing clinical trials for the treatment of different types of cancer. The common drawback limiting their use in clinical practice is an inability to distinguish between BET-members that may cause side effects and resistances. The selective targeting of individual BET and the discrimination between BD1 and BD2 present an opportunity to achieve more selective transcriptional effect. A midthroughput screening of previously designed chemical library allowed identification of two molecules with unique profiles of selectivity that have never been observed. An undertaken structure-based program revealed a minimum scaffolds necessary for binding. Taking together with resolved X-Ray structures it allowed the development of more potent and selective BET inhibitors by DOTS (diversity oriented target focused synthesis) strategy, combining virtual screening and diversity oriented library design. This optimization led to a potent inhibitor with up to 100-fold improvement of affinity to the target and up to 300-fold selectivity toward BD1. Dose-response downregulation of c-Myc levels in low micromolar range in cell assays allowed the validation of the identified molecule as a chemical probe. Further comprehensive in vitro and in vivo evaluations of this compound will enable elucidating the biological role of each bromodomain and a validation of the interest toward the development of selective inhibitors in clinic
Abdel-Rahman, Tarek. "Mixture of Factor Analyzers (MoFA) Models for the Design and Analysis of SAR Automatic Target Recognition (ATR) Algorithms." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1500625807524146.
Full textSarabi, Andisheh. "Logic Synthesis with High Testability for Cellular Arrays." PDXScholar, 1994. https://pdxscholar.library.pdx.edu/open_access_etds/4752.
Full textJavaheri, Fatemeh Negin. "Synthèse automatique de circuits numériques à partir de spécifications temporelles." Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAT083/document.
Full textThe work presented in this thesis aims at automatically prototype communication and control designs from declarative temporal specifications. From a set of PSL properties, we produce a synthesizable RTL design automatically. The proposed method is modular, in contrast to previously published methods that were based on automata theory. From each property, we produce a component that observes some operands and generates waveforms for the other operands: the reactant. First, a library of primitive reactants has been provided for FL and SERE operators. To this goal, a dependency relation is defined for each operator that expresses the dependency among its operands using the operator's semantics. Then, the dependency relation of each operator is interpreted as a hardware component that implements the operator: the operator's primitive reactant. Using this formalization, a method is proposed to automatically decide which signals of a property are observed and which are generated. In the cases when specifying the signal direction is not possible, a solver is implemented to identify the signal value. In addition, the way of identifying the value of the signal that is generated in several properties is addressed. The final circuit is the interconnection of the properties' reactants and solvers. A prototype tool SyntHorus2, which is an extension to HORUS, has been developed. It takes PSL properties as its inputs, and generates the synthesizable VHDL code of the circuit. In addition, it generates some complementary properties to verify if the set of specification is coherent and complete. The method is efficient, and synthesizes control circuits in a few seconds. Results obtained on classical benchmarks show that our technique compiles properties more efficiently than previous prototype tools
Moraes, Fernando Gehm. "Synthese topologique de macro-cellules en technologie cmos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1994. http://hdl.handle.net/10183/17853.
Full textThe main problems of the automatic layout synthesis are the design rules dependence and the transistor sizing. The traditional layout synthesis methods, like standard-cells, are not flexible, since the cells in the libraries are designed and sized for a specific technology. In this way, the designer must change his library at each technology improvement. The automatic layout synthesis methods overcomes these problems (design rules dependence and transistor sizing). Examples of layout styles are gate-matrix and linear-matrix. The technology independence is achieved by symbolic description (layout under an unitary grid), and the transistor sizes are defined by the designer or by a sizing tool. From these two constraints, we develop an automatic layout synthesis tool, using a linear-matrix multi-row layout style. The input description for our tool is a Spice file. This descriptions allows to define a greater number of cells (mainly AOIs gates), resulting a technology mapping with less constraints. The generated macro-cells must be assembled in order to construct a complete circuit. Two additional constraints are then imposed to the generator : variable aspect ratio and placement of the inputs/outputs pins in the macro-cell border. The macro-cells are assembled by an industrial CAD environment. The main contributions of this thesis are the development of a macro-cell generator (with the characteristics of technology independence and easy integration in a macro-cell environment) and the analysis of the parameters playing a role in the area, delay and power consumption.
Samanta, Roopsha. "Program reliability through algorithmic design and analysis." 2013. http://hdl.handle.net/2152/23103.
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SUN, LI-FANG, and 孫黎芳. "Design of an automated synthesis for digital systems." Thesis, 1988. http://ndltd.ncl.edu.tw/handle/08685163938876241298.
Full textNicaise, Fabien. "Automated Design Synthesis of Structures using Growth Enhanced Evolution." Thesis, 2008. https://thesis.library.caltech.edu/5231/1/main.pdf.
Full textEngineering design is a complex problem on generating and evaluating a variety of options. In traditional methods, this typically involves evaluating up to a dozen different point designs. The limit on the process is the amount of time to generate, refine, and evaluate the various concepts. Using a computer helps to speed up the process, but human involvement still remains the weakest link.
The natural extension of this process is to continually and rapid generate, refine, and evaluate concepts entirely automatically. Evolutionary Algorithms provide such a method, by emulating natural evolution. The computer maintains a population point design, each of which is represented by a gene string that is allowed to change (mutate) and combine with other genes (crossover). At each generation, every individual is modified then evaluated and the improved solutions proceed to the next generation.
This thesis will extend the biological model by introducing a growth process to each individual. This is akin to the concept of a multi-cellular organism developing in the womb. An encoding for discrete truss structures is described that provides for such an extension. The truss grows from a few basic elements. After showing several examples demonstrating the growth process, the method is applied to a couple simple examples using evolutionary algorithms.
Williams, Joshua Murry. "Automated conceptual design of manufacturing workcells in radioactive environments." 2013. http://hdl.handle.net/2152/21429.
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Mirjafari, Mehran. "Automated Synthesis Tool for Design Optimization of Power Electronic Converters." Thesis, 2013. http://hdl.handle.net/1969.1/149257.
Full textRadhakrishnan, Pradeep 1984. "Automated design of planar mechanisms." Thesis, 2014. http://hdl.handle.net/2152/24806.
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Pal, Ujjwal. "A Computational Platform For Automated Identification Of Building Blocks In Mechanical Design For Enhancing Ideation." Thesis, 2012. http://hdl.handle.net/2005/2555.
Full textCheng, Yue Lung, and 鄭玉龍. "Design of an automated structured fault tree synthesis method based on system decomposition." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/55098151839570610272.
Full textRadhakrishnan, Pradeep 1984. "A graph grammar scheme for representing and evaluating planar mechanisms." Thesis, 2010. http://hdl.handle.net/2152/ETD-UT-2010-05-1393.
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Patel, Jay K. 1978. "An approach to automate the synthesis of sheet metal parts." 2008. http://hdl.handle.net/2152/17895.
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Lee, Cin-Young. "Efficient Automatic Engineering Design Synthesis Via Evolutionary Exploration." Thesis, 2002. https://thesis.library.caltech.edu/6369/1/Lee_c_2002.pdf.
Full textJie, Yung, and 羅永杰. "Automatic Synthesis Design for Energy Harvesting IC Systems." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/26486938212238586982.
Full text國立高雄第一科技大學
電子工程研究所
99
In this paper, an automatic design tool for energy-harvesting circuit and system is developed with the visual basic (VB) software. The synthesis tool can be used to shorten the design time to market. The design has charge controller and maximum power point tracking (MPPT), in order to achieve optimal battery charging control function. Meanwhile, a smart metering system is developed to measure the energy-harvesting system’s information with an online system. In this way, users can get the proposed system’s information at any time and from anywhere. Finally, computer simulations and experimental results demonstrate the superior performance of the proposed technique. Three chips are finished in this thesis. All of the chips had been taped out through the design flow of the Chip Implementation Center (CIC). These chips are analog pulse-width modulator (APWM) IC, digital pulse-width modulator (DPWM) IC, and analog to digital converter (ADC) IC, respectively. The ICs are combined with an 8-bit microcontroller chip to implement the novel solar charger.
Bell, Robert Henry. "Automatic workload synthesis for early design studies and performance model validation." Thesis, 2005. http://hdl.handle.net/2152/2392.
Full textChung, Ching-Che, and 鍾菁哲. "Automatic Synthesis of Timing-Locked Loops for SoC Designs." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/79566070446025129456.
Full text國立交通大學
電子工程系
92
In this dissertation, the designs for All-Digital Phase-Locked Loop (ADPLL) and All-Digital Delay-Locked Loop (ADDLL) are presented. The proposed flexible ADPLL/ADDLL architectures can easily be modified to fit different applications and achieve fast lock-in time. The proposed automated synthesis methodology uses both benefits of digital VSLI and cell-based design to build up user-specified ADPLL/ADDLL in a short time, making it very suitable for System-on-Chip (SoC) applications. This dissertation first presents a scheme to overcome the limitations of standard cells and to build up high resolution delay cell and high sensitivity Phase and Frequency detector (PFD). Then the proposed fine-tuning delay cell and PFD are applied to ADPLL/ADDLL. Time-to-Digital Converter (TDC) is widely used in the proposed ADPLL/ADDLL architecture to reduce frequency/phase acquisition time. Then design for the proposed DLL-based All-Digital Multi-phase Clock Generator (ADMCG) is presented. In ADMCG design, TDC is used to choose a suitable delay range to avoid false-lock to harmonics. Finally, a synthesis approach for ADPLL/ADDLL/ADMCG design is presented. As a result, the gate-level Hardware Description Language (HDL) codes of ADPLL/ADDLL/ADMCG can be automatically generated using standard cells from cell-library. Hence both design time and design complexity of ADPLL/ ADDLL/ADMCG is greatly reduced by the proposed methodology.