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Journal articles on the topic 'Autonomic adjusting'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Jordan, Jens, Ulrich Limper, and Jens Tank. "Cardiovascular autonomic nervous system responses and orthostatic intolerance in astronauts and their relevance in daily medicine." Neurological Sciences 43, no. 5 (2022): 3039–51. http://dx.doi.org/10.1007/s10072-022-05963-7.

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Abstract Background The harsh environmental conditions during space travel, particularly weightlessness, impose a major burden on the human body including the cardiovascular system. Given its importance in adjusting the cardiovascular system to environmental challenges, the autonomic nervous system has been in the focus of scientists and clinicians involved in human space flight. This review provides an overview on human autonomic research under real and simulated space conditions with a focus on orthostatic intolerance. Methods The authors conducted a targeted literature search using Pubmed.

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PETROV, K. V., E. YU MOZHEYKO, E. G. SHANINA, and A. V. PETROV. "Autonomic dysfunction syndrome in patients who underwent COVID-19, at stage 3 of medical rehabilitation." Practical medicine 21, no. 6 (2023): 149–54. http://dx.doi.org/10.32000/2072-1757-2023-6-149-154.

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At the moment, post-COVID-19 syndrome is a poorly studied aspect of the past pandemic, the clinical signs of which largely coincide with the symptoms of autonomic dysfunction. When examining patients who underwent COVID-19, symptoms of the autonomic nervous system disorder are often revealed. The use of vegetative status assessment methods will allow detecting, confirming and adjusting a rehabilitation program for such patients. The purpose — to analyze the results of the vegetative status assessment in patients who underwent COVID-19, admitted to post-COVID rehabilitation. Material and method

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Romanchuk, A.P., O.D. Grechko, and Yu.A. Perevoschikov. "Autonomic adjusting of activity of cardio-vessel system of girls of the prepubescence period, engaged in dancing aerobic." Pedagogika, psihologia ta mediko-biologicni problemi fizicnogo vihovanna i sportu 2010, no. 3 (2015): 71–74. https://doi.org/10.5281/zenodo.16390.

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The vegetative adjusting of activity of the cardio-vessel system of girls is investigational. In an experiment took part girls of 9-12 years old. A type of sport is a dancing aerobics. The indexes of general power of spectrum of variability of cardiac rhythm are presented, systole and diastole arteriotony. Motion of the adaptation re-erecting is appraised under influence of the physical loadings in the conditions of current and operative control. Certain change activity and tone of vegetative influences on the cardio-vessel system. They determine the features of the further adaptation re-erect

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Mitsuishi, Hisashi, and Mikitoshi Tabuchi. "Effects of Adjusting Backpack Shoulder Stabilizers on Psychological Responses and Autonomic Nerve Activity in Hiking." Health 17, no. 01 (2025): 1–12. https://doi.org/10.4236/health.2025.171001.

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Junqueira Junior, Luiz Fernando. "Insights into the clinical and functional significance of cardiac autonomic dysfunction in Chagas disease." Revista da Sociedade Brasileira de Medicina Tropical 45, no. 2 (2012): 243–52. http://dx.doi.org/10.1590/s0037-86822012000200020.

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INTRODUCTION: Exclusive or associated lesions in various structures of the autonomic nervous system occur in the chronic forms of Chagas disease. In the indeterminate form, the lesions are absent or mild, whereas in the exclusive or combined heart and digestive disease forms, they are often more pronounced. Depending on their severity these lesions can result mainly in cardiac parasympathetic dysfunction but also in sympathetic dysfunction of variable degrees. Despite the key autonomic effect on cardiovascular functioning, the pathophysiological and clinical significance of the cardiac autonom

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Wu, Wei-te, Yu-Jen Lin, and Saou-Hsing Liou. "P.2.35 Heart rate variability and sleep-related breathing disorders in commercial drivers." Occupational and Environmental Medicine 76, Suppl 1 (2019): A96.1—A96. http://dx.doi.org/10.1136/oem-2019-epi.262.

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BackgroundSleep-related breathing disorders, such as obstructive sleep apnea (OSA), seems to have an important influence on the autonomic nervous function on the heart, and associated with cardiovascular mortality. Therefore, we assessed the relations of sleep apnea-related parameters with 5 min heart rate variability (HRV) in a large cohort of male commercial drivers.MethodsThis cross-sectional study recruited 245 male bus drivers from one transportation company in Taiwan. Each participant was evaluated by a polysomnography (PSG) test and by blood lipids examination. Severity of OSA was categ

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Maduro, Paula Andreatta, Luiz Alcides Ramires Maduro, Polyana Evangelista Lima, et al. "Cardiac Autonomic Modulation and Cognitive Performance in Community-Dwelling Older Adults: A Preliminary Study." Neurology International 17, no. 5 (2025): 74. https://doi.org/10.3390/neurolint17050074.

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Background/Objectives: Cognitive decline has been increasingly linked to cardiac autonomic regulation; however, its specific associations with cognitive domains, such as information processing speed and executive function, remain unclear. This preliminary study examined the relationship between cardiac autonomic modulation and cognitive performance in older adults. Methods: A cross-sectional study was conducted with 101 older adults (aged ≥60 years) attending a university hospital outpatient clinic. Participants were classified as without cognitive impairment (WCI) or cognitively impaired and

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Anand, A., P. Bhati, A. Mujaddadi, S. Verma, I. H. Naqvi, and M. E. Hussain. "Influence of physical activity on cardiac autonomic control in patients with dyslipidaemia." Comparative Exercise Physiology 15, no. 4 (2019): 233–41. http://dx.doi.org/10.3920/cep190024.

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The objective of this study was to compare the cardiac autonomic control of dyslipidaemia patients engaged in different levels of physical activity and to determine the predictive ability of physical activity for cardiac autonomic dysfunction in these patients. This study also aimed to compare the cardiac autonomic control of dyslipidaemia patients and healthy adults. 52 patients (age: 49.1±4.53 years) with dyslipidaemia were recruited along with 16 healthy adults. Physical activity levels were assessed by International Physical Activity Questionnaire, and subjects were divided into three cate

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Liu, Lei, Qiansheng Wu, Hong Yan, Baoxian Chen, Xilong Zheng, and Qiang Zhou. "Association between Cardiac Autonomic Neuropathy and Coronary Artery Lesions in Patients with Type 2 Diabetes." Disease Markers 2020 (December 30, 2020): 1–6. http://dx.doi.org/10.1155/2020/6659166.

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Objective. Cardiac autonomic neuropathy (CAN) is a common and serious complication of diabetes mellitus with various systemic involvements, such as atherosclerotic cardiovascular disease. We aimed to evaluate the association between CAN and coronary artery lesions in patients with type 2 diabetes. Research Design and Methods. We retrospectively reviewed the medical records of 104 patients with type 2 diabetes and coronary artery disease (CAD). We evaluated heart rate variability (HRV) parameters (SDANN, SDNN, and pNN50) to assess cardiac autonomic function. The severity of coronary lesions was

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Yang, Xubin, Qiongyan Lin, Xiaoshan Li, et al. "Cystatin C Is an Important Biomarker for Cardiovascular Autonomic Dysfunction in Chinese Type 2 Diabetic Patients." Journal of Diabetes Research 2019 (March 18, 2019): 1–9. http://dx.doi.org/10.1155/2019/1706964.

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Background. Cardiovascular autonomic dysfunction is closely related to increased mortality in patients with diabetes. Previous studies have proved that cystatin C (CysC) is an important predictor of both peripheral neuropathy and cardiovascular events. However, whether CysC is also associated with cardiovascular autonomic dysfunction remains unclear. Therefore, the aim of this study was to investigate the relationship between CysC and cardiovascular autonomic dysfunction in type 2 diabetic patients without renal dysfunction. Methods. A total of 161 type 2 diabetic patients with normal serum cr

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Morales-Ghinaglia, Natasha, Susan Calhoun, Jason Liao, et al. "0199 Circadian Misalignment, Cardiac-Autonomic and Inflammatory Pathways, and Metabolic Syndrome in Adolescents." SLEEP 47, Supplement_1 (2024): A86. http://dx.doi.org/10.1093/sleep/zsae067.0199.

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Abstract Introduction Although insufficient sleep is a known risk factor for metabolic syndrome (MetS), circadian misalignment, which is highly prevalent during adolescence, may also impact cardiac, autonomic and immune regulation. Prior studies have shown that circadian misalignment impacts the association between visceral adiposity (VAT) and MetS in youth, which is not explained by lifestyle factors such as diet or physical activity. We hypothesize that cardiac-autonomic and inflammatory pathways will significantly diminish the impact of circadian misalignment on the relationship between VAT

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de Souza, Euzébio D., and Eduardo José Lima II. "Autonomic Computing in a Biomimetic Algorithm for Robots Dedicated to Rehabilitation of Ankle." International Journal of Grid and High Performance Computing 9, no. 1 (2017): 48–60. http://dx.doi.org/10.4018/ijghpc.2017010105.

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Human mobility is the key element of everyday life, its reduction or loss deeply affects daily activities. In assisted rehabilitation, robotic devices have focuses on the biomechanics of motor control. However, biomechanics does not study the neurological and physiological processes related to normal gait. Biomimetics combined with biomechanics, can generate a more efficient stimulation of the motor cortex and the locomotor system. The highest efficiency obtained through torque generation models, based on the physiological response of muscles and bones to reaction forces, together with control

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Goodman, Brent P., Daniel Claassen, and Ali Mehdirad. "Adjusting droxidopa for neurogenic orthostatic hypotension in a patient with Parkinson disease." Clinical Autonomic Research 27, S1 (2017): 17–19. http://dx.doi.org/10.1007/s10286-017-0431-9.

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Wegeberg, Anne-Marie L., Tina Okdahl, Tina Fløyel, et al. "Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes." Mediators of Inflammation 2020 (August 18, 2020): 1–10. http://dx.doi.org/10.1155/2020/3590389.

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Introduction. A neuroimmune communication exists, and compelling evidence suggests that diabetic neuropathy and systemic inflammation are linked. Our aims were (1) to investigate biomarkers of the ongoing inflammation processes including cytokines, adhesion molecules, and chemokines and (2) to associate the findings with cardiovascular autonomic neuropathy in type 1 diabetes by measuring heart rate variability and cardiac vagal tone. Materials and Methods. We included 104 adults with type 1 diabetes. Heart rate variability, time domain, and frequency domains were calculated from a 24-hour Holt

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Eskandarnejad, Mahta, Leila Heidary, Parisa Mohammadzadeh, and Masumeh Zamanlu. "Swimmers’ Extremity Temperature: From Autonomy of Vessels Toward the Joy of Swimming." Journal of Vessels and Circulation 4, no. 1 (2023): 23–28. http://dx.doi.org/10.32598/jvc.4.1.47.5.

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Background and Aim: Autonomic psychophysiology has opened a new field in modern sports science and practice, providing effective means to improve swimming training and skills. Of the famous items of this technology is extremity temperature, which gives an estimate of pleasure and autonomic balance. Nevertheless, the literature on this area and swimming shows a significant gap. This study measures and interprets the extremity temperature of swimmers during swimming training, which can be beneficial for adjusting training approaches and designing neuroscience interventions (including biofeedback

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DiMario, Francis J., Barbara Dunham, Joseph A. Burleson, Jay Moskovitz, and Suzanne B. Cassidy. "An Evaluation of Autonomic Nervous System Function in Patients With Prader-Willi Syndrome." Pediatrics 93, no. 1 (1994): 76–81. http://dx.doi.org/10.1542/peds.93.1.76.

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Objective. Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder in which many cardinal features may have a neurologically based patho-physiology involving both the central and peripheral components of the autonomic nervous system. Autonomic nervous system function was studied noninvasively in a group of subjects with PWS and control subjects to determine whether autonomic nervous system dysfunction exists as part of the PWS. Design/setting. This cross-sectional study was performed in the neurophysiology laboratory at a tertiary care facility. Methods. Evaluation included anthr

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Vichayanrat, Ekawat, Shiwen Koay, Gordon Ingle, et al. "032 Supine hypertension and cardiovascular autonomic failure in patients with alpha-synucleinopathies." Journal of Neurology, Neurosurgery & Psychiatry 93, no. 9 (2022): e2.226. http://dx.doi.org/10.1136/jnnp-2022-abn2.76.

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IntroductionOrthostatic hypotension (OH) and supine hypertension (SH) are prevalent in alpha-synucle- inopathies, posing a therapeutic dilemma as OH treatment may worsen SH. We aimed to characterise SH in pure autonomic failure (PAF), multiple system atrophy (MSA), and Lewy body disorders (LBD: Parkinson’s disease and Dementia with Lewy bodies).Methods166 patients (72 PAF, 59 MSA, 35 LBD) underwent cardiovascular autonomic testing and 24hr- ambulatory blood pressure monitoring (24hr-ABPM). Demographic, clinical features, medications and cardiovascular autonomic biomarkers were compared.Results

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Huang, Yao-Ming, Wu-Chien Chien, Chun-Gu Cheng, Yin-Han Chang, Chi-Hsiang Chung, and Chun-An Cheng. "Females with Diabetes Mellitus Increased the Incidence of Premenstrual Syndrome." Life 12, no. 6 (2022): 777. http://dx.doi.org/10.3390/life12060777.

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Background: Premenstrual syndrome (PMS) is a multifactorial disorder caused by hormone and autonomic imbalance. In our study, hyperglycemia-induced insulin secretion increased progesterone secretion and progressive autonomic imbalance. The young patients with diabetes mellitus (DM) revealed hypo-parasympathetic function and hypersympathetic function compared with nondiabetic controls. Young female patients with DM with higher blood sugar and autonomic malfunction may be associated with PMS. However, there is a lack of evidence about DM in females related to PMS. We evaluated female patients wi

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Guo, Qingyu, Pu Zang, Shaoying Xu, et al. "Time in Range, as a Novel Metric of Glycemic Control, Is Reversely Associated with Presence of Diabetic Cardiovascular Autonomic Neuropathy Independent of HbA1c in Chinese Type 2 Diabetes." Journal of Diabetes Research 2020 (February 6, 2020): 1–11. http://dx.doi.org/10.1155/2020/5817074.

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Objective. The objective of this study is to investigate the relationship between time in range (TIR), a new metric of continuous glucose monitoring (CGM) and cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes mellitus (T2DM). Methods. A total of 349 individuals with T2DM were enrolled in this study. Evaluating by the standard cardiac autonomic reflex tests (CARTs), there were 228 diabetic individuals without cardiovascular autonomic neuropathy (without confirmed CAN) including absent CAN (n=83 cases) and early CAN (n=145 cases) and 121 diabetic individuals complicat

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Zhang, Jingjie, Qingtao Wu, Ruijuan Zheng, Junlong Zhu, Mingchuan Zhang, and Ruoshui Liu. "A Security Monitoring Method Based on Autonomic Computing for the Cloud Platform." Journal of Electrical and Computer Engineering 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/8309450.

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With the continuous development of cloud computing, cloud security has become one of the most important issues in cloud computing. For example, data stored in the cloud platform may be attacked, and its security is difficult to be guaranteed. Therefore, we must attach weight to the issue of how to protect the data stored in the cloud. To protect data, data monitoring is a necessary process. Based on autonomic computing, we develop a cloud data monitoring system on the cloud platform, monitoring whether the data is abnormal in the cycle and analyzing the security of the data according to the mo

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Wang, Mei-Yeh, Chen-Huan Chiu, Hsin-Chien Lee, Chien-Tien Su, and Pei-Shan Tsai. "Cardiovascular Reactivity in Patients With Major Depressive Disorder With High- or Low-Level Depressive Symptoms." Biological Research For Nursing 18, no. 2 (2015): 221–29. http://dx.doi.org/10.1177/1099800415596227.

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Depression increases the risk of adverse cardiac events. Cardiovascular reactivity is defined as the pattern of cardiovascular responses to mental stress. An altered pattern of cardiovascular reactivity is an indicator of subsequent cardiovascular disease. Because depression and adverse cardiac events may have a dose-dependent association, this study examined the differences in cardiovascular reactivity to mental stress between patients with major depressive disorder (MDD) with high depression levels and those with low depression levels. Moreover, autonomic nervous system regulation is a highl

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Zhu, Xiaoming, Fei Mao, Siying Liu, Hangping Zheng, Bin Lu, and Yiming Li. "Association of SUDOSCAN Values with Vibration Perception Threshold in Chinese Patients with Type 2 Diabetes Mellitus." International Journal of Endocrinology 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/8435252.

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Aims/Introduction. SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. Materials and Methods. A total of 920 Chinese patients with T2DM were enrolled in the study. Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between CAN and VPT values. Mean VPT values across the CAN value tertiles were analyzed stratified by

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Park, Manyong, and Sungchul Kim. "A Modern Clinical Approach of the Traditional Korean Saam Acupuncture." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/703439.

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Saam acupuncture is one of the original therapeutic modalities representing traditional Korean medicine. It was originally described in a manuscript that is estimated to be published at some point between 1644 and 1742, in the middle of the Cho Sun dynasty, by a Korean Buddhist monk whose name is unknown. The principle of combining five shu points is based on the theory of Nan-jing. The treatment and diagnosis concepts in Saam acupuncture were mainly influenced by Dongeuibogam and Chimgoogyeong-heombang. The basic characteristic of combining five shu points in Saam acupuncture is the selection

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Rafael, Freitas Reale, Martins da S. Bezerra Romildo, and S. B. Martins Joberto. "Applying Autonomy with Bandwidth Allocation Models." International Journal of Communication Systems 29, no. 13 (2016): 2028–40. https://doi.org/10.5281/zenodo.1287914.

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Bandwidth Allocation Models (BAMs) are resource allocation methods used for networks in general. BAMs are currently applied for handling resources such as bandwidth allocation in MPLS DS-TE networks (LSP setup). In general, BAMs defines resource restrictions by “class” and allocate the available resources on demand. This is frequently necessary to manage large and complex systems like routing networks. GBAM is a new generalized BAM that, by configuration, incorporates the “behavior” of existing BAMs (MAM, RDM, G-RDM and AllocTC-Sharing). In effect, any current available

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Waki, Hideaki, Takuya Suzuki, Yuki Tanaka, et al. "Effects of Electroacupuncture to the Trigeminal Nerve Area on the Autonomic Nervous System and Cerebral Blood Flow in the Prefrontal Cortex." Acupuncture in Medicine 35, no. 5 (2017): 339–44. http://dx.doi.org/10.1136/acupmed-2016-011247.

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Background The autonomic nervous system and trigeminal nerve are involved in adjusting flow through diverging cerebral arteries in the prefrontal cortex. The purpose of this study was to examine the effect of 100 Hz electroacupuncture (EA) to the trigeminal nerve area on cerebral blood flow and autonomic nervous system function. Method This was a randomised crossover study of 16 healthy volunteers who were assigned to an EA or control group. Stimulation (in the EA group) was performed five times, each after 1 min of rest. Needles were inserted at the inner edge of the eyebrows and 1 cm from th

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Hempel Zinglersen, A., K. K. Iversen, J. Eugen-Olsen, J. Fleischer, and S. Jacobsen. "AB0466 DYSFUNCTION OF THE AUTONOMIC NERVOUS SYSTEM IS ASSOCIATED WITH LOW-GRADE INFLAMMATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1360. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1237.

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BackgroundSystemic lupus erythematosus (SLE) is characterized by chronic, systemic inflammation, organ damage and -dysfunction. Autonomic nervous system dysfunction is highly prevalent in SLE patients (up to 54%); compared to controls the prevalence may be up to 12 times increased.1 These numbers parallel findings in other chronic conditions such as diabetes.2Heart rate variability (HRV) reflects autonomic activity, and low variability indicates impaired activity, denoted as autonomic dysfunction (AD). AD is associated with low-grade inflammation in healthy subjects and patients with diabetes

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Robles-Cabrera, Adriana, Claudia Lerma, Silvia Ruiz-Velasco Acosta, Iván Pérez-Díaz, and Ruben Fossion. "Sex hormones correlate with heart rate variability in healthy women and this correlation is conserved in women with well-controlled type 2 diabetes mellitus." PLOS ONE 20, no. 4 (2025): e0320982. https://doi.org/10.1371/journal.pone.0320982.

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The autonomic nervous system and the endocrine system regulate cardiovascular physiology, and their alterations, as occurs in type 2 diabetes mellitus, are related to the development of cardiovascular complications. Sex hormones are major regulators of both cardiovascular and nervous tissue, and during postmenopause, the lack in hormone production can increase the risk for cardiovascular and autonomic diseases, even more in metabolic impairment such as in T2DM However, the evidence regarding whether sex hormones are related to autonomic activity is inconclusive. The goal of this paper was to e

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Tong, B., G. Stewart, J. Flood, P. de Chazal, and P. Cistulli. "O068 Vascular and Autonomic Function in Comorbid Insomnia and Sleep Apnoea." Sleep Advances 5, Supplement_1 (2024): A24—A25. https://doi.org/10.1093/sleepadvances/zpae070.068.

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Abstract Comorbid insomnia and sleep apnoea (COMISA) is a common sleep disorder and may be associated with increased cardiovascular risk. This study aimed to compare polysomnography-derived biomarkers of cardiovascular risk in patients with COMISA, obstructive sleep apnoea (OSA) only, insomnia only, and without OSA or insomnia. Patients were identified from the Sydney Sleep Biobank database. Insomnia was defined as a positive test on the Insomnia Symptom Questionnaire (self-report of poor sleep and daytime impairment at least three times per week for four weeks). COMISA was defined as having i

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Cheng, Hong, Shuang-Shuang Zhuo, Xin Rong, et al. "Value of Contrast-Enhanced Ultrasound in Adjusting the Classification of Chinese-TIRADS 4 Nodules." International Journal of Endocrinology 2022 (January 6, 2022): 1–6. http://dx.doi.org/10.1155/2022/5623919.

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Objectives. To explore the value of applying contrast-enhanced ultrasound (CEUS) in adjusting the classification of category 4 nodules in the Chinese-Thyroid Imaging Report and Data System (C-TIRADS). Methods. The data of preoperative conventional ultrasound and CEUS examinations of 125 C-TIRADS 4 nodules in 109 patients were retrospectively analyzed. We divided the thyroid nodules into two groups based on whether recommend by the guide fine-needle aspiration (FNA). Group I included C-TIRADS 4A nodules with a maximum diameter ≤15 mm and C-TIRADS 4B and 4C nodules with a maximum diameter ≤10 mm

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Belokrylov, I., S. Semikov, A. Tkhostov, E. Rasskazova, and A. Yavorovskaya. "Cognitive and behavioral factors of quality of life in patients with somatoform disorders." European Psychiatry 64, S1 (2021): S192—S193. http://dx.doi.org/10.1192/j.eurpsy.2021.510.

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IntroductionStudies of the cognitive and behavioral factors of perpetuation and quality of life in patients with somatoform disorders are important for identifying targets for psychological interventions and risk groups (Piontek et al., 2018, Dehoust et al., 2017, Schaefer et al., 2012, Flasinski et al., 2020).ObjectivesTo reveal beliefs and behavior in patients with somatoform disorders associated severity of somatic complaints and poorer subjective well-being.Methods125 patients with somatoform disorders 17-68 years old filled Screening for Somatoform Symptoms (Rief, Hiller, 2003), Cognition

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Weinstein, Galit, Kendra Davis-Plourde, Alexa S. Beiser, and Sudha Seshadri. "Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study." Stroke 52, no. 6 (2021): 2068–76. http://dx.doi.org/10.1161/strokeaha.120.030601.

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Background and Purpose: The autonomic nervous system has been implicated in stroke and dementia pathophysiology. High resting heart rate and low heart rate variability indicate the effect of autonomic imbalance on the heart. We examined the associations of resting heart rate and heart rate variability with incident stroke and dementia in a community-based cohort of middle- and old-aged adults. Methods: The study sample included 1581 participants aged >60 years and 3271 participants aged >45 years evaluated for incident dementia and stroke, respectively, who participated in the Framingham

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Yu, Peng, Xi Xu, Jing Zhang, et al. "Liraglutide Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism via SHP1/AMPK Signaling Pathway." International Journal of Endocrinology 2019 (May 19, 2019): 1–11. http://dx.doi.org/10.1155/2019/1567095.

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A glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide (LR) had been experimentally and clinically shown to ameliorate nonalcoholic fatty liver disease (NAFLD). This study aimed to investigate the beneficial effect of LR on NAFLD in vivo and in vitro and its underlying molecular mechanism. The effects of LR were examined on the high-fat diet-induced in vivo model in mice and in vitro model of NAFLD in human HepG2 cells. Liver tissues and HepG2 cells were procured for measuring lipid metabolism, histological examination, and western blot analysis. LR administration significantly lowered

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Mohammadieh, A., H. Dissanayake, K. Sutherland, S. Ucak, P. de Chazal, and P. Cistulli. "P095 Heart Rate Variability during Sleep in Paroxysmal Atrial Fibrillation patients with and without Obstructive Sleep Apnoea." SLEEP Advances 2, Supplement_1 (2021): A52. http://dx.doi.org/10.1093/sleepadvances/zpab014.139.

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Abstract Introduction Physiological studies have demonstrated the importance of the autonomic nervous system in mediating acute apnoea-induced atrial fibrillation (AF). We aimed to compare Heart Rate Variability (HRV) markers of autonomic function in paroxysmal atrial fibrillation (PAF) patients with and without obstructive sleep apnoea (OSA). A secondary aim was the analysis of ectopic beats in these groups. Methods Nocturnal ECG traces from 89 PAF patients who underwent in-laboratory polysomnography were included. After identifying ectopic beats in the ECGs, periods of arrhythmia as well as

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Hu, Guoliang, Jean-Paul Collet, Mengxi Zhao, Yao Lu, and Yilong Wang. "Associations between Autonomic Function and Cognitive Performance among Patients with Cerebral Small Vessel Disease." Brain Sciences 13, no. 2 (2023): 344. http://dx.doi.org/10.3390/brainsci13020344.

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Data linking heart rate variability (HRV) and cognitive status remains controversial and scarce, particularly in cerebral small vessel disease (CSVD) patients. Whether the association between HRV and cognitive performance exists in CSVD patients is unclear. Hence, we aimed to investigate the association between HRV and cognitive performance in patients with CSVD. This cross-sectional study was conducted among 117 CSVD patients. All patients underwent HRV assessment and global cognitive evaluation by the Mini-Mental-State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Multivariabl

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Sandoz, Vania, Suzannah Stuijfzand, Alain Lacroix, et al. "The Lausanne Infant Crying Stress Paradigm: Validation of an Early Postpartum Stress Paradigm with Women at Low vs. High Risk of Childbirth-Related Posttraumatic Stress Disorder." Journal of Personalized Medicine 11, no. 6 (2021): 472. http://dx.doi.org/10.3390/jpm11060472.

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Stress reactivity is typically investigated in laboratory settings, which is inadequate for mothers in maternity settings. This study aimed at validating the Lausanne Infant Crying Stress Paradigm (LICSP) as a new psychosocial stress paradigm eliciting psychophysiological stress reactivity in early postpartum mothers (n = 52) and to compare stress reactivity in women at low (n = 28) vs. high risk (n = 24) of childbirth-related posttraumatic stress disorder (CB-PTSD). Stress reactivity was assessed at pre-, peri-, and post-stress levels through salivary cortisol, heart rate variability (high-fr

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Zhang, Junwen, Jiaquan Zhu, Shiao Ding, et al. "Analysis of the Synergistic Effects of Fasting Plasma Glucose and Hypertension on Cardiovascular Autonomic Neuropathy." Cardiology 132, no. 1 (2015): 58–64. http://dx.doi.org/10.1159/000381013.

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Background: The purpose of this study was to evaluate the associations of fasting plasma glucose (FPG) and hypertension (HTN) with cardiovascular autonomic neuropathy (CAN) and to estimate the extent to which the synergistic effects of FPG and HTN affect outcomes in a Chinese population. Method: We conducted a large-scale, population-based study to analyze the association and interaction of the two factors with CAN in a sample of 2,092 Chinese people. Univariate and multiple linear regression (MLR) analyses were employed to detect these relationships. Interaction on an additive scale can be ca

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SADJADI, S. MASOUD, and FERNANDO TRIGOSO. "TRAP.NET: A REALIZATION OF TRANSPARENT SHAPING IN .NET." International Journal of Software Engineering and Knowledge Engineering 19, no. 04 (2009): 507–28. http://dx.doi.org/10.1142/s0218194009004258.

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We define adaptability as the capacity of software in adjusting its behavior in response to changing conditions. To list just a few examples, adaptability is important in pervasive computing, where software in mobile devices need to adapt to dynamic changes in wireless networks; autonomic computing, where software in critical systems are required to be self-manageable; and grid computing, where software for long running scientific applications need to be resilient to hardware crashes and network outages. In this paper, we provide a realization of the transparent shaping programming model, call

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Oskarsson, Sofi, Ralf Kuja-Halkola, Antti Latvala, et al. "Low autonomic arousal as a risk factor for reoffending: A population-based study." PLOS ONE 16, no. 8 (2021): e0256250. http://dx.doi.org/10.1371/journal.pone.0256250.

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Background Low resting heart rate (RHR) and low systolic blood pressure (SBP) are associated with criminal behavior. However, knowledge is lacking about their predictive value for reoffending. Aim We aimed to examine associations of RHR and SBP with reoffending in a large population-based sample. Methods We conducted a cohort study of all convicted male conscripts born in Sweden 1958–1990 (N = 407,533). We obtained data by linking Swedish population-based registers. Predictor variables were RHR and SBP, measured at conscription which was mandatory until 2010 for men at age 18. The outcome vari

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Patoglu, O., L. Walter, M. Davey, G. Nixon, B. Edwards, and R. Horne. "O046 Autonomic Control of Heart Rate in Growth Hormone Naïve Children with Prader-Willi Syndrome." Sleep Advances 5, Supplement_1 (2024): A17. https://doi.org/10.1093/sleepadvances/zpae070.046.

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Abstract Background Adults with Prader Willi syndrome (PWS) have an increased risk of cardiovascular morbidity and mortality, which may be due to impaired autonomic control. Heart rate variability (HRV) has been used in different populations as a strong and independent predictor of cardiac mortality and diseases. Studies have not assessed cardiovascular control in children with PWS during sleep while accounting for sleep disordered breathing severity which affects HRV. Methods Overnight electrocardiogram recordings during routine sleep studies in children with PWS pre-growth hormone treatment

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Sivakumar, Siddharth S., Amalia G. Namath, Ingrid E. Tuxhorn, Stephen J. Lewis, and Roberto F. Galán. "Decreased heart rate and enhanced sinus arrhythmia during interictal sleep demonstrate autonomic imbalance in generalized epilepsy." Journal of Neurophysiology 115, no. 4 (2016): 1988–99. http://dx.doi.org/10.1152/jn.01120.2015.

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We hypothesized that epilepsy affects the activity of the autonomic nervous system even in the absence of seizures, which should manifest as differences in heart rate variability (HRV) and cardiac cycle. To test this hypothesis, we investigated ECG traces of 91 children and adolescents with generalized epilepsy and 25 neurologically normal controls during 30 min of stage 2 sleep with interictal or normal EEG. Mean heart rate (HR) and high-frequency HRV corresponding to respiratory sinus arrhythmia (RSA) were quantified and compared. Blood pressure (BP) measurements from physical exams of all s

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Stewart, G., B. Tong, J. Flood, and P. Cistulli. "O053 Relationship between cardiovascular risk and pulse wave amplitude characteristics in a sleep clinic cohort." Sleep Advances 5, Supplement_1 (2024): A19. https://doi.org/10.1093/sleepadvances/zpae070.053.

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Abstract Introduction Novel pulse oximetry-derived measures of autonomic vasoreactivity have recently been developed as a biomarker of cardiovascular outcomes in patients with obstructive sleep apnoea (OSA). It is currently unclear if these measures relate to general cardiovascular risk in an unselected population undergoing polysomnography. Methods This study examined pulse wave amplitude characteristics (from photoplethysmography) in 547 individuals who underwent a diagnostic in-laboratory polysomnogram and had sufficient clinical data to calculate a modified Framingham cardiovascular risk s

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Lopez-Duran, Nestor L., Stefanie E. Mayer, and James L. Abelson. "Modeling neuroendocrine stress reactivity in salivary cortisol: adjusting for peak latency variability." Stress 17, no. 4 (2014): 285–95. http://dx.doi.org/10.3109/10253890.2014.915517.

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Che, Ning-Ning, Shuai Chen, Qiu-Huan Jiang, et al. "Corneal confocal microscopy differentiates patients with Parkinson’s disease with and without autonomic involvement." npj Parkinson's Disease 8, no. 1 (2022). http://dx.doi.org/10.1038/s41531-022-00387-8.

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AbstractAutonomic dysregulation in Parkinson’s disease (PD) can precede motor deficits and is associated with reduced quality of life, disease progression, and increased mortality. Objective markers of autonomic involvement in PD are limited. Corneal confocal microscopy (CCM) is a rapid ophthalmic technique that can quantify small nerve damage in a range of peripheral and autonomic neuropathies. Here we investigated whether CCM can be used to assess autonomic symptoms in PD. Based on the scale for outcomes in Parkinson’s disease for autonomic symptoms (SCOPA-AUT), patients with PD were classif

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Dae, Won Lee, Hyung Park Ji, Eom Sinae, Hyun Cho Syung, Soo Lee Jong, and Sung Kim Han. "Effects of Combined Stimulation on the Autonomic Nervous System: A Pilot Study." December 27, 2011. https://doi.org/10.5281/zenodo.1075316.

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The autonomic nervous system has a regulatory structure that helps people adapt to changes in their environment by adjusting or modifying some functions in response to stress, and regulating involuntary function of human organs. The purpose of this study was to investigate the effect of combined stimulation, both far-infrared heating and chiropractic, on the autonomic nervous system activities using thermal image and heart rate variability. Six healthy subjects participated in this test. We compared the before and after autonomic nervous system activities through obtaining thermal image and ph

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Evers, Stefan, Achim Frese, Patrick Hornberg, and Oliver Summ. "Trigemino-autonomic activation in a human trigeminal pain model." BMC Neurology 25, no. 1 (2025). https://doi.org/10.1186/s12883-025-04147-y.

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Abstract Background Autonomic symptoms are mandatory for making the diagnosis of a trigemino-autonomic cephalalgia (TAC). These symptoms can occasionally also occur in migraine and facial pain disorders. This leads to the question whether the trigeminal pain itself can induce autonomic symptoms also in healthy subjects. Methods We enrolled healthy subjects without a history of migraine or a TAC and provoked severe trigeminal pain by injection of 0.05 ml capsaicin (0.01%) into the right forehead. Autonomic symptoms occurring at the right eye or right nostril were registered until they disappear

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Shaltout, Hossam A., Kathleen M. Hayden, Katelyn R. Garcia, et al. "Sleep, autonomic function, and cognition in the U.S. POINTER trial." Alzheimer's & Dementia 20, S7 (2024). https://doi.org/10.1002/alz.092320.

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AbstractBackgroundSleep disorders have been associated with cognitive impairment and dementia risk. Measures of autonomic function including baroreflex sensitivity (BRS) and heart rate variability (HRV) have also been associated with sleep quality. The extent to which sleep disorders are linked to autonomic function and alter the risk of Alzheimer’s disease (AD) in older adults remains unclear. We investigated the association between sleep measures and autonomic function measures in 193 participants enrolled in the U.S. POINTER trial (mean age: 67.8±5.4 years, 65% female, 35% people of color).

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Baek, Ji Hyun, Simran S. Grewal, Krystel Abi Karam, et al. "Neurobiological Mechanisms Link Bipolar Disorder to Cardiovascular Disease: A Retrospective Biobank Study of Adverse Event Risk and Contributory Mechanisms." Bipolar Disorders, January 30, 2025. https://doi.org/10.1111/bdi.13516.

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ABSTRACTObjectiveIndividuals with bipolar disorder are at greater risk of developing cardiovascular disease. However, the mechanisms underlying this association remain poorly understood. This study aimed to (1) determine the risk of major adverse cardiovascular events (MACE) after adjusting for important confounders and (2) evaluate the neural, autonomic, and immune mechanisms underlying the link between bipolar disorder and cardiovascular disease.MethodsLeveraging the Mass General Brigham Biobank, bipolar disorder and incident MACE were identified using the International Classification of Dis

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Walsh, Emily, Andre Diedrich, Italo Biaggioni, and Luis E. Okamoto. "Abstract P413: Association Between Supine Hypertension And Autonomic Impairment In Patients With Autonomic Failure." Hypertension 80, Suppl_1 (2023). http://dx.doi.org/10.1161/hyp.80.suppl_1.p413.

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Autonomic failure is characterized by an inability to regulate blood pressure (BP). The dominant clinical manifestation of these patients is orthostatic hypotension (OH). However, at least half of them also have supine hypertension, which can arise de novo or due to worsening of preexisting essential hypertension. We hypothesized that, regardless of the cause of hypertension, the loss of baroreflex buffering capacity in these patients contributes to the severity of their hypertension. Thus, we tested whether supine hypertension reflects the severity of autonomic impairment (i.e., reduced BP bu

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Johansen, Ingrid T., Nils Eiel Steen, Linn Rødevand, et al. "Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles." Schizophrenia 10, no. 1 (2024). http://dx.doi.org/10.1038/s41537-023-00430-4.

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AbstractAutonomic adverse effects of antipsychotic drugs (APs) cause clinical challenges, but few studies have investigated sex differences and their underlying biological pathways. Sex-specific regulation of relevant hormones could be involved. We investigated sex differences in autonomic adverse effects related to olanzapine, quetiapine, risperidone, and aripiprazole, and the role of hormones related to APs. Patients with severe mental disorders (N = 1318) were included and grouped based on AP monotherapy: olanzapine (N = 364), quetiapine (N = 211), risperidone (N = 102), aripiprazole (N = 1

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Shaltout, Hossam A., Katelyn R. Garcia, Laura D. Baker, et al. "Association between autonomic function, depressive symptoms, and cognitive function in cognitively normal older adults in U.S. POINTER trial." Alzheimer's & Dementia 20, S7 (2024). https://doi.org/10.1002/alz.092656.

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AbstractBackgroundAutonomic dysfunction and depression are among the most common causes of disability in high‐income countries and depression has been associated with deficits in various cognitive domains. The degree to which depression associates with autonomic function and modifies risk for Alzheimer’s disease (AD) in older adults is unknown. We investigated the association between depression status and autonomic function measures in 398 participants enrolled in the U.S. POINTER trial (mean age: 68.0±5.3 years, 61% female, 32% people of color).MethodsContinuous blood pressure and ECG recordi

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