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Journal articles on the topic 'AVM-2'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Kurian, Susan, and V. S. Josekumar. "PHYTOCHEMICAL SCREENING, ANTIMICROBIAL ACTIVITY AND BRINE SHRIMP LETHALITY BIOASSAY OF DIFFERENT EXTRACTS OF ALYSICARPUS VAGINALIS VAR. NUMMULARIFOLIUS (DC.) MIQ. (FAMILY: FABACEAE)." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 1 (2016): 1. http://dx.doi.org/10.22159/ijpps.2017v9i1.15688.

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<p><strong>Objective: </strong>To evaluate the antimicrobial activity and cytotoxicity of hexane, ethyl acetate and methanol extracts of <em>Alysicarpus vaginalis </em>var<em>. nummularifolius </em>(DC) along with phytochemical analysis.</p><p><strong>Methods: </strong>The crude extract of hexane (AVH), ethyl acetate (AVE) and methanol (AVM) of <em>Alysicarpus vaginalis </em>var<em>. nummularifolius </em>(DC) were prepared and analysed for phytochemical constituents using standard methods. The cytotoxicit

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Kurian, Susan, Leenamma Joseph, and Josekumar V. S. "PHYTOCHEMICAL ANALYSIS AND IN VITRO FREE RADICAL SCAVENGING ACTIVITY OF SUCCESSIVE EXTRACTS OF ALYSICARPUS VAGINALIS VAR. NUMMULARIFOLIUS (DC.) MIQ." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 6 (2017): 231. http://dx.doi.org/10.22159/ijpps.2017v9i6.16814.

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Objective: The present study was carried to evaluate free radical scavenging activity and phytochemical analysis of successive extraction with hexane (AVH), ethyl acetate (AVE) and methanol (AVM) of Alysicarpus vaginalis var. nummularifolius (DC.) MIQ., a herb used in home remedies.Methods: The entire plant was dried and powdered, successively extracted (soxhlet apparatus) and concentrated using rotary vacuum evaporator. The extracts were quantitatively analyzed for phytochemicals like total phenolic, flavonoids, alkaloids and carbohydrates following standard methods. The free radical scavengi

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Lopes, Demetrius K., Bradley Bagan, and Kalani Wells. "Onyx Embolization of Arteriovenous Malformations Using 2 Microcatheters." Neurosurgery 66, no. 3 (2010): 616–19. http://dx.doi.org/10.1227/01.neu.0000365368.08451.08.

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Abstract OBJECTIVE To report an operative technique using 2 microcatheters placed in different arterial pedicles for Onyx (ev3 Neurovascular, Inc, Irvine, CA) embolization of cerebral arteriovenous malformations (AVMs). TECHNIQUE Two cases illustrate this approach to embolization of AVMs. Microcatheters are placed in 2 different arterial pedicles of the AVM. Subsequently, the embolic material is injected in an alternate fashion between the microcatheters until occlusion of the AVM. CONCLUSION The 2-microcatheter technique for embolization of AVMs with Onyx was performed safely. The technique a

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Pollock, Bruce E., and John C. Flickinger. "A proposed radiosurgery-based grading system for arteriovenous malformations." Journal of Neurosurgery 96, no. 1 (2002): 79–85. http://dx.doi.org/10.3171/jns.2002.96.1.0079.

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Object. Radiosurgery is an effective treatment strategy for properly selected patients harboring arteriovenous malformations (AVMs). Grading scales that are currently used to predict patient outcomes after AVM resection are unreliable tools for the prediction of the results of AVM radiosurgery. Methods. A grading system was developed to predict outcomes following AVM radiosurgery, based on the multivariate analysis of data obtained in 220 patients treated between 1987 and 1991 (Group 1). The dependent variable in all analyses was excellent patient outcome (complete AVM obliteration without any

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Russell, Stephen M., Henry H. Woo, Seth S. Joseffer, and Jafar J. Jafar. "Role of Frameless Stereotaxy in the Surgical Treatment of Cerebral Arteriovenous Malformations: Technique and Outcomes in a Controlled Study of 44 Consecutive Patients." Neurosurgery 51, no. 5 (2002): 1108–18. http://dx.doi.org/10.1097/00006123-200211000-00002.

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Abstract OBJECTIVE To describe a frameless stereotactic technique used to resect cerebral arteriovenous malformations (AVMs) and to determine whether frameless stereotaxy during AVM resection could decrease operative times, minimize intraoperative blood losses, reduce postoperative complications, and improve surgical outcomes. METHODS Data for 44 consecutive patients with surgically resected cerebral AVMs were retrospectively reviewed. The first 22 patients underwent resection without stereotaxy (Group 1), whereas the next 22 patients underwent resection with the assistance of a frameless ster

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Brinjikji, Waleed, Vivek N. Iyer, Christopher P. Wood, and Giuseppe Lanzino. "Prevalence and characteristics of brain arteriovenous malformations in hereditary hemorrhagic telangiectasia: a systematic review and meta-analysis." Journal of Neurosurgery 127, no. 2 (2017): 302–10. http://dx.doi.org/10.3171/2016.7.jns16847.

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OBJECTIVEPatients with hereditary hemorrhagic telangiectasia (HHT) are known to suffer from high rates of cerebral arteriovenous malformations (AVMs). The authors performed a systematic review and meta-analysis of the literature examining prevalence rates, characteristics, and clinical presentation of cerebral AVMs in the HHT population.METHODSTo identify studies on AVM prevalence and characteristics in the HHT population, 4 databases (MEDLINE, EMBASE, Scopus and Web of Science) were searched by a reference librarian with over 30 years experience in systematic reviews and meta-analysis. The se

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Rozhchenko, L. V., N. V. Dryagina, S. A. Goroshchenko, N. V. Rozhchenko, K. A. Samochernikh, and A. E. Petrov. "MMP9 as a likely predictor of de novo aneurysm formation in a group of cerebral arteriovenous malformations with AVM-associated aneurysms." Russian Neurosurgical Journal named after Professor A. L. Polenov 15, no. 2 (2023): 88–97. https://doi.org/10.56618/2071-2693_2023_15_2_88.

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SUMMARY. Timely and complete diagnosis of AVM-associated aneurysms is essential to prevent the risk of intracranial haemorrhage. AVM-associated aneurysms are found in 12–46 % of patients with AVMs, which is many times the incidence of cerebral aneurysms in the population. When an AVM is combined with an aneurysm, the risk of haemorrhage is 9.8 % per year, increasing the risk of recurrent intracranial haemorrhage to 53.6 %, whereas when there is no such combination, haemorrhage occurs in only 1.7 % of patients with an AVM per year. Currently, there is no consensus on the management tactics for

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Andrade-Souza, Yuri M., Gelareh Zadeh, Meera Ramani, Daryl Scora, May N. Tsao, and Michael L. Schwartz. "Testing the radiosurgery-based arteriovenous malformation score and the modified Spetzler—Martin grading system to predict radiosurgical outcome." Journal of Neurosurgery 103, no. 4 (2005): 642–48. http://dx.doi.org/10.3171/jns.2005.103.4.0642.

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Object. The aim of this study was to validate the radiosurgery-based arteriovenous malformation (AVM) score and the modified Spetzler—Martin grading system to predict radiosurgical outcome. Methods. One hundred thirty-six patients with brain AVMs were randomly selected. These patients had undergone a linear accelerator radiosurgical procedure at a single center between 1989 and 2000. Patients were divided into four groups according to an AVM score, which was calculated from the lesion volume, lesion location, and patient age (Group 1, AVM score < 1; Group 2, AVM score 1–1.49; Group 3, AVM s

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Shi, Siyu, Raghav Gupta, Justin M. Moore, et al. "De novo AVM formation following venous sinus thrombosis and prior AVM resection in adults: report of 2 cases." Journal of Neurosurgery 128, no. 2 (2018): 506–10. http://dx.doi.org/10.3171/2016.9.jns161710.

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Brain arteriovenous malformations (AVMs) are traditionally considered congenital lesions, arising from aberrant vascular development during the intrauterine period. Rarely, however, AVMs develop in the postnatal period. Individual case reports of de novo AVM formation in both pediatric and adult patients have challenged the traditional dogma of a congenital origin. Instead, for these cases, a dynamic picture is emerging of AVM growth and development, initially triggered by ischemic and/or traumatic events, coupled with genetic predispositions. A number of pathophysiological descriptions involv

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Guglielmi, G. "Electrical Models in the Analysis of Hemodynamic Characteristics of Arteriovenous Malformations." Interventional Neuroradiology 12, no. 1 (2006): 9–15. http://dx.doi.org/10.1177/159101990601200103.

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This paper describes the creation of two electric arteriovenous malformation (AVM) models where electric resistors simulate AVM vessels. The flow of electrons simulates the flow of blood. Using the models, it was possible to analyze the pressure and flow patterns in the nidus of a small, low-flow AVM and in the nidus of a large, high-flow AVM. “Normal” hemodynamic “physiologic” conditions of the two AVMs were studied, including the autoregulation of normal brain surrounding the AVMs. It is the first time that the hemodynamics within the different parts of the nidus (arterious, arteriolar, venu

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Yuki, Ichiro, Robert H. Kim, Gary Duckwiler, et al. "Treatment of brain arteriovenous malformations with high-flow arteriovenous fistulas: risk and complications associated with endovascular embolization in multimodality treatment." Journal of Neurosurgery 113, no. 4 (2010): 715–22. http://dx.doi.org/10.3171/2009.9.jns081588.

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Object High-flow fistulas associated with brain arteriovenous malformations (AVMs) pose a significant challenge to both stereotactic radiosurgery (SRS) and surgical treatment. The purpose of this study was to examine the outcomes of multimodality treatment of AVMs in association with a large arteriovenous fistula (AVF), with a special focus on endovascular embolization and its associated complications. Methods One hundred ninety-two patients harboring cerebral AVMs underwent endovascular treatment in the authors' department between 1997 and 2003. Of these, the authors selected 74 patients pres

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Yokoya, Shigeomi, Hidesato Takezawa, Yukihiro Hidaka, Gaku Fujiwara, and Hideki Oka. "Ultrasound localization of embolic material to guide resection of brain AVM: Report of two cases." Surgical Neurology International 14 (April 21, 2023): 146. http://dx.doi.org/10.25259/sni_242_2023.

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Background: The Spetzler–Martin Grade (SMG) is widely used to evaluate the risk of resection of cerebral arteriovenous malformation (AVM), and direct surgery is strongly recommended for low SMG lesions. Micro-AVMs are defined as AVMs with a nidus <1 cm in diameter, and sometimes, the challenge is identifying the exact lesion site during AVM resection, although identification of the site is very important in the procedure. Here, we present two cases in which the sites of micro-AVM were marked using presurgical embolization and easily confirmed by intraoperative ultrasonography (IUS) and disc

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Yılmaz, Baran, Zafer Orkun Toktaş, Akın Akakın, et al. "Familial occurrence of brain arteriovenous malformation: a novel ACVRL1 mutation detected by whole exome sequencing." Journal of Neurosurgery 126, no. 6 (2016): 1879–83. http://dx.doi.org/10.3171/2016.6.jns16665.

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OBJECTIVEBrain arteriovenous malformations (AVMs) can occur in patients with hereditary hemorrhagic telangiectasia (HHT). However, brain AVM without HHT has also been reported. Using whole exome sequencing, the authors performed comprehensive genomic characterization of a 6-person Turkish family with 3 cases of brain AVM without HHT.METHODSThree siblings with brain AVM, one of whom also had spinal AVM, were evaluated. The parents and the fourth sibling had no AVM on cranial MRI. The authors performed a whole exome capture and Illumina sequencing on blood samples from 2 siblings with AVM.RESULT

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Samonenko, Yu M., D. V. Shchehlov, O. E. Sviridyuk, A. V. Naida, and O. V. Slobodian. "Endovascular and microsurgical treatment for spinal arteriovenous malformations. Our experience." Endovascular Neuroradiology 27, no. 1 (2019): 32–40. http://dx.doi.org/10.26683/2304-9359-2019-1(27)-32-40.

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Objective – to improve the treatment quality for patients with spinal arteriovenous malformations (AVM).Materials and methods. A retrospective analysis of endovascular and surgical treatment of patients was made. In SO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine» since 2005 till 2018 were operated 55 patients (34 (61.8 %) men and 21 (38.2 %) women). The age of patients ranged from 11 to 62 years (middle age is 45.3 years). The classification proposed by Anson and Spetzler in 1992 was used in order to divide patients into experimental groups: type I, arteriovenou

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Burkhardt, Jan-Karl, Ethan A. Winkler, Joshua S. Catapano, Robert F. Spetzler, and Michael T. Lawton. "Surgical selection and outcomes among elderly patients with brain arteriovenous malformations." Neurosurgical Focus 49, no. 4 (2020): E9. http://dx.doi.org/10.3171/2020.7.focus20464.

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OBJECTIVEStudies of resection of brain arteriovenous malformations (AVMs) in the elderly population are scarce. This study examined factors influencing patient selection and surgical outcome among elderly patients.METHODSPatients 65 years of age and older who underwent resection of an unruptured or ruptured brain AVM treated by two surgeons at two centers were identified. Patient demographic characteristics, AVM characteristics, clinical presentation, and outcomes measured using the modified Rankin Scale (mRS) were analyzed. For subgroup analyses, patients were dichotomized into two age groups

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Liew, Jason A., Wuyang Yang, Leila A. Mashouf, et al. "Incidence of Spontaneous Obliteration in Untreated Brain Arteriovenous Malformations." Neurosurgery 86, no. 1 (2019): 139–49. http://dx.doi.org/10.1093/neuros/nyz047.

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Abstract BACKGROUND Spontaneous obliteration (SpO) of untreated arteriovenous malformations (AVMs) is rare with fewer than 100 cases reported. The incidence and predisposing factors of SpO remain unclear, impeding our understanding of lesion progression in untreated patients. OBJECTIVE To determine the incidence rate and predisposing factors of SpO in a North American cohort. METHODS AVMs were retrospectively evaluated at our institution for over 25 yr. Untreated AVMs were divided into 2 groups: SpO-AVMs and non-SpO-AVMs. All statistical results were based on univariate analyses. Incidence was

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Geibprasert, Sasikhan, Vitor Pereira, Timo Krings, Pakorn Jiarakongmun, Pierre Lasjaunias, and Sirintara Pongpech. "Hydrocephalus in unruptured brain arteriovenous malformations: pathomechanical considerations, therapeutic implications, and clinical course." Journal of Neurosurgery 110, no. 3 (2009): 500–507. http://dx.doi.org/10.3171/2008.7.jns0815.

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Object The goal in this study was to present possible pathological mechanisms, clinical and imaging findings, and to describe the management and outcome in patients with hydrocephalus due to unruptured pial brain arteriovenous malformations (AVMs). Methods Medical records and imaging findings in 8 consecutive patients with hydrocephalus caused by AVMs and treated between June 2000 and September 2007 were retrospectively reviewed to determine clinical symptoms, AVM location, venous drainage, level/cause of obstruction, and degree of hydrocephalus. Management of hydrocephalus, AVM treatment, com

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Beaty, Narlin B., Jessica K. Campos, Geoffrey P. Colby, et al. "Pipeline Flex Embolization of Flow-Related Aneurysms Associated with Arteriovenous Malformations: A Case Report." Interventional Neurology 7, no. 3-4 (2018): 164–70. http://dx.doi.org/10.1159/000484986.

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Background: An estimated 0.1% of the population harbors brain arteriovenous malformations (AVMs). Diagnosis and workup of AVMs include thorough evaluation for characterization of AVM angioarchitecture and careful assessment for concomitant aneurysms. The presence of coexisting aneurysms is associated with an increased risk of intracranial hemorrhage, with a published risk of 7% per year compared to patients with AVMs alone with a risk of 3%. Comprehensive AVM management requires recognition of concomitant aneurysms and prioritizes treatment strategies to mitigate the aggregate risk of intracra

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Aboukaïs, Rabih, Matthieu Vinchon, Mathilde Quidet, Philippe Bourgeois, Xavier Leclerc, and Jean-Paul Lejeune. "Reappearance of arteriovenous malformations after complete resection of ruptured arteriovenous malformations: true recurrence or false-negative early postoperative imaging result?" Journal of Neurosurgery 126, no. 4 (2017): 1088–93. http://dx.doi.org/10.3171/2016.3.jns152846.

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OBJECTIVE Ruptured arteriovenous malformations (AVMs) are often obliterated after emergency microsurgical treatment. However, some studies have reported AVM recurrence after the obliteration of ruptured AVMs. The authors report their experience with AVM recurrence after successful microsurgical treatment of ruptured AVMs. METHODS The authors reviewed the medical data of 139 consecutive patients who underwent microsurgery at the authors' institution for ruptured AVM between 2002 and 2012. Each patient underwent a conventional cerebral angiography examination immediately after the surgery. Subse

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Walkden, James S., Zsolt Zador, Amit Herwadkar, and Ian D. Kamaly-Asl. "Use of intraoperative Doppler ultrasound with neuronavigation to guide arteriovenous malformation resection: a pediatric case series." Journal of Neurosurgery: Pediatrics 15, no. 3 (2015): 291–300. http://dx.doi.org/10.3171/2014.10.peds14249.

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OBJECT Over the last 20 years, several intraoperative adjuncts, including ultrasonography, neuronavigation, and angiography, have been said to aid the intraoperative localization and resection of cerebral arteriovenous malformations (AVMs). The authors assessed the value of intraoperative Doppler ultrasonography in conjunction with neuronavigation during surgery for cerebral AVMs in the pediatric population. METHODS The authors reviewed all cranial AVM resections performed by a single surgeon at their institution in the period from 2007 to 2013 and here describe their experience and results in

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Tamaki, Norihiko, Kazumasa Ehara, Tin-Kai Lin, et al. "Cerebral Arteriovenous Malformations: Factors Influencing the Surgical Difficulty and Outcome." Neurosurgery 29, no. 6 (1991): 856–63. http://dx.doi.org/10.1227/00006123-199112000-00009.

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Abstract The outcomes of 151 patients with arteriovenous malformations (AVMs) treated either surgically or conservatively are presented. In terms of long-term survival rate and follow-up results, the patients who underwent total excision had more favorable results than did those treated conservatively. Patient age was the most important clinical factors, with the preoperative level of consciousness being the second most important. A grading system was formulated on the basis of the angiographical factors by using multiregression analysis; the size of the AVM influenced the surgical outcome twi

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Chen, Ching-Jen, Srinivas Chivukula, Dale Ding, et al. "Seizure outcomes following radiosurgery for cerebral arteriovenous malformations." Neurosurgical Focus 37, no. 3 (2014): E17. http://dx.doi.org/10.3171/2014.6.focus1454.

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Object Seizures are a common presentation of cerebral arteriovenous malformations (AVMs). The authors evaluated the efficacy of stereotactic radiosurgery (SRS) for the management of seizures associated with AVMs and identified factors influencing seizure outcomes following SRS for AVMs. Methods A systematic literature review was performed using PubMed. Studies selected for review were published in English, included at least 5 patients with both cerebral AVMs and presenting seizures treated with SRS, and provided post-SRS outcome data regarding obliteration of AVMs and/or seizures. Demographic,

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Starke, Robert M., Chun-Po Yen, Dale Ding, and Jason P. Sheehan. "A practical grading scale for predicting outcome after radiosurgery for arteriovenous malformations: analysis of 1012 treated patients." Journal of Neurosurgery 119, no. 4 (2013): 981–87. http://dx.doi.org/10.3171/2013.5.jns1311.

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Object The authors performed a study to review outcomes following Gamma Knife radiosurgery for cerebral arteriovenous malformations (AVMs) and to create a practical scale to predict long-term outcome. Methods Outcomes were reviewed in 1012 patients who were followed up for more than 2 years. Favorable outcome was defined as AVM obliteration and no posttreatment hemorrhage or permanent, symptomatic, radiation-induced complication. Preradiosurgery patient and AVM characteristics predictive of outcome in multivariate analysis were weighted according to their odds ratios to create the Virginia Rad

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Shchehlov, D. V., M. S. Gudym, O. E. Svyrydiuk, I. M. Bortnik, and M. B. Vyval. "Combined (microsurgical and endovascular) treatment of cerebral arteriovenous malformations." Endovascular Neuroradiology 29, no. 3 (2020): 21–26. http://dx.doi.org/10.26683/2304-9359-2019-3(29)-21-26.

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Objective – to analyze the results of combined microsurgical and endovascular treatment of brain arteriovenous malformations (AVM).Materials and methods. Radiological and clinical data of 19 patients who underwent preoperative endovascular embolization and resection of the AVM at the SO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine» in 2014–2019 were analyzed. Among patients were 11 (57.9 %) women and 8 (42.1 %) men. The average age of patient was 28.4 year (from 15 to 54 years). All AVMs were I–III grade according to the Spetzler–Martin scale.Results. The average

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Barnett, Gene H., John R. Little, Zeyd Y. Ebrahim, Stephen C. Jones, and Harry T. Friel. "Cerebral Circulation during Arteriovenous Malformation Operation." Neurosurgery 20, no. 6 (1987): 836–42. http://dx.doi.org/10.1227/00006123-198706000-00003.

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Abstract The circulatory changes in the cortex around a cerebral arteriovenous malformation (AVM) were studied in 18 patients. The AVMs had rapid circulation times with early draining veins on angiography. Local cortical blood flow (ICoBF) was measured with cortically applied thermister/Peltier stack arrays. The AVMs had a more pronounced effect on ICoBF at a 2- to 4-cm distance from the AVM margin than in the adjacent cortex. Mean preexcision ICoBF was 62.9 ± 6.7 (SE) ml/100 g/minute (i.e., similar to normal controls) near the AVM margin and 43.0 ± 4.2 ml/100 g/minute far (i.e., &gt;2 cm)

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Barone, Damiano G., Hani J. Marcus, Mathew R. Guilfoyle, et al. "Clinical Experience and Results of Microsurgical Resection of Arterioveonous Malformation in the Presence of Space-Occupying Intracerebral Hematoma." Neurosurgery 81, no. 1 (2017): 75–86. http://dx.doi.org/10.1093/neuros/nyx003.

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Abstract BACKGROUND: Management of ruptured arteriovenous malformations (AVMs) with a mass-producing intracerebral hematoma (ICH) represents a surgical dilemma. OBJECTIVE: To evaluate the clinical outcome and obliteration rates of microsurgical resection of AVM when performed concomitantly with evacuation of an associated space-occupying ICH. METHODS: Data of patients with AVM were collected prospectively. Cases were identified in which an AVM was resected and an associated space-occupying ICH was evacuated at the same time, and divided into “group 1,” in which the surgery was performed acutel

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Yarotskyi, Yu R., L. M. Yakovenko, M. Yu Orlov, A. G. Lugovskyi, V. V. Moroz, and I. I. Skorokhoda. "Combined surgical treatment of the cerebral arteriovenous malformations in patients with the torpid course of the disease." Endovascular Neuroradiology 30, no. 4 (2020): 38–48. http://dx.doi.org/10.26683/2304-9359-2019-4(30)-38-48.

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Objective – to optimize the results of surgical treatment of the cerebral arteriovenous malformations (AVM) with a torpid clinical course of the disease.Materials and methods. The results of combined surgical treatment of cerebral AVMs of 36 patients without a history of AVM rupture were analyzed (this variant of clinical course was defined as «torpid»). Patients were treated in the departments of vascular neurosurgery at the Romodanov Neurosurgery Institute NAMS of Ukraine during the period from 2010 till September 2019. Among the patients there were 18 (50 %) men and 18 (50 %) women. The ave

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Lv, Xianli, Peng Liu, and Youxiang Li. "Pre-existing, incidental and hemorrhagic AVMs in pregnancy and postpartum: Gestational age, morbidity and mortality, management and risk to the fetus." Interventional Neuroradiology 22, no. 2 (2015): 206–11. http://dx.doi.org/10.1177/1591019915622161.

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Objective The objective of this article is to analyze the maternal and fetal outcomes of pregnancies that present with arteriovenous malformations (AVMs). Methods A literature review was performed that analyzed 65 cases of AVM during pregnancy previously reported in English literature. Results Sixty-five cases of pregnancy-associated AVM were identified. The patients’ ages ranged from 16 to 45 years, with a mean of 28 ± 4.9 years. Sixteen cases (24.6%) were pre-existing AVMs. There were 54 cases (83.1%) of AVM ruptured during pregnancy and postpartum: Six cases (11.1%) were in the first trimes

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Velat, Gregory J., Steve W. Chang, Adib A. Abla, Felipe C. Albuquerque, Cameron G. McDougall, and Robert F. Spetzler. "Microsurgical management of glomus spinal arteriovenous malformations: pial resection technique." Journal of Neurosurgery: Spine 16, no. 6 (2012): 523–31. http://dx.doi.org/10.3171/2012.3.spine11982.

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Object Intramedullary, or glomus, spinal arteriovenous malformations (AVMs) are rare vascular lesions amenable to resection with or without adjuvant embolization. The authors retrospectively reviewed the senior author's (R.F.S.'s) surgical series of intramedullary spinal AVMs to evaluate clinical and radiographic outcomes. Methods Detailed chart and radiographic reviews were performed for all patients with intramedullary spinal AVMs who underwent surgical treatment between 1994 and 2011. Presenting and follow-up neurological examination results were obtained and graded using the modified Ranki

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Kano, Hideyuki, Nathaniel Sisterson, Dale Ding, et al. "124 Repeat Stereotactic Radiosurgery for Incompletely Obliterated Arteriovenous Malformations: An International Multicenter Study." Neurosurgery 64, CN_suppl_1 (2017): 227–28. http://dx.doi.org/10.1093/neuros/nyx417.124.

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Abstract INTRODUCTION To evaluate the outcomes and risks of repeat stereotactic radiosurgery (SRS) for incompletely obliterated cerebral arteriovenous malformations (AVM). METHODS Six participating centers of the International Gamma Knife Research Foundation (IGKRF) identified 335 patients who had incompletely obliterated AVMs at a median follow-up of 45.6 months after initial SRS (range, 15–283 months). The median AVM target volume at initial SRS was 4.3 cc but was reduced to 1.4cc at the time of the second procedure. The median margin dose at both initial SRS and repeat SRS was 20 Gy. The me

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Woodhams, Reiko, Go Ogasawara, Kenichiro Ishida, et al. "Successful treatment of acquired uterine arterial venous malformation using N-butyl-2-cyanoacrylate under balloon occlusion." Acta Radiologica Short Reports 3, no. 8 (2014): 204798161454591. http://dx.doi.org/10.1177/2047981614545910.

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We present two cases of acquired uterine arterial venous malformation (AVM) which was diagnosed because of massive genital bleeding successfully treated with transcatheter arterial embolization (TAE), using N-butyl-2-cyanoacrylate (NBCA) under balloon occlusion. Balloon occlusion at the uterine artery was performed in both patients for diffuse distribution of NBCA in multiple feeding branches, as well as to the pseudoaneurysm, and for the prevention of NBCA reflux. In one of our patients, balloon occlusion of the draining vein was simultaneously performed to prevent NBCA migration through acco

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Nagashima, H., K. Hongo, S. Kobayashi, et al. "Embolization of Arteriovenous Malformation." Interventional Neuroradiology 10, no. 2_suppl (2004): 54–58. http://dx.doi.org/10.1177/15910199040100s211.

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Treatment options for cerebral arteriovenous malformation (AVM) are still controversial due to the recent result of stereotactic radiosurgery and the improved result of microsurgical resection. We investigated previously treated AVM cases and discussed the efficacy and safety of preoperative embolization especially for microsurgical resection of high-grade AVM in the Spetzler-Martin grading. Efficacy of preoperative embolization was evaluated based on 126 previously treated AVM cases at Shinshu University Hospital during the last 25 years. The safety of embolization was evaluated based on our

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Sharma, Gopal Raman, Prasanna Karki, Sumit Joshi, Prakash Paudel, Damber Bikram Shah, and Apurva Sharma. "Surgical outcome of brain arteriovenous malformation according to the location, A retrospective study." Nepal Journal of Neuroscience 20, no. 2 (2023): 17–27. http://dx.doi.org/10.3126/njn.v20i2.51780.

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Background and Objective: The goal of this study was to analyze the association of brain arteriovenous malformations (AVMs) location and its outcome after microsurgical excision. The relation of outcome using modified Ranklin Scale (mRS) at time of discharge, early and last follow ups with respect to location of AVM. Methods: Demographic data, AVM characteristics, and treatment outcomes were evaluated in 47 bAVMs treated with microsurgery between November 2009 and April 2021. For this series, 47 patients were retrospectively reviewed. The mRS was used to assess functional outcome post-surgery

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Ding, Dale, Robert M. Starke, Hideyuki Kano, et al. "International multicenter cohort study of pediatric brain arteriovenous malformations. Part 1: Predictors of hemorrhagic presentation." Journal of Neurosurgery: Pediatrics 19, no. 2 (2017): 127–35. http://dx.doi.org/10.3171/2016.9.peds16283.

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OBJECTIVE Brain arteriovenous malformations (AVMs) are the most common cause of spontaneous intracranial hemorrhage in pediatric patients (age < 18 years). Since the cumulative lifetime risk of AVM hemorrhage is considerable in children, an improved understanding of the risk factors influencing hemorrhagic presentation may aid in the management of pediatric AVMs. The aims of this first of a 2-part multicenter, retrospective cohort study are to evaluate the incidence and determine the predictors of hemorrhagic presentation in pediatric AVM patients. METHODS The authors analyzed pooled AVM ra

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Codd, Patrick J., Alim P. Mitha, and Christopher S. Ogilvy. "A recurrent cerebral arteriovenous malformation in an adult." Journal of Neurosurgery 109, no. 3 (2008): 486–91. http://dx.doi.org/10.3171/jns/2008/109/9/0486.

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Arteriovenous malformations are generally considered to be cured following angiographically proven complete resection. However, rare instances of AVM recurrence despite negative findings on postoperative angiography have been reported in both children and adults. In this paper, the authors present the case of a 33-year-old woman with 2 AVM recurrences. This patient represents the oldest case of recurrent AVM, and the first adult double recurrence reported in the literature. The case is presented, the radiological and surgical features are considered, and the literature on recurrent AVMs is rev

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Bertolini, Gladson Ricardo Flor, Taciane Stein da Silva, Adriano Polican Ciena, and Elisângela Lourdes Artifon. "Comparação do ultrassom pulsado e contínuo no reparo tendíneo de ratos." Fisioterapia e Pesquisa 19, no. 3 (2012): 242–47. http://dx.doi.org/10.1590/s1809-29502012000300009.

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No tratamento de lesões tendíneas, o uso do ultrassom surge como possibilidade terapêutica, apesar de lacunas sobre seus efeitos clínicos. O objetivo foi avaliar dois protocolos de ultrassom terapêutico sobre dor e edema após trauma tendíneo. Vinte e um ratos Wistar foram submetidos a trauma no tendão calcâneo e divididos em três grupos: sham (GS); ultrassom contínuo (GUC); e ultrassom pulsado (GUP). O trauma ocorreu sobre a face lateral do tendão calcâneo direito, com energia de 0,40 J. A dor foi avaliada pelo teste de incapacidade funcional e o edema, pelo diâmetro laterolateral. Foram reali

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Celix, Juanita M., James G. Douglas, David Haynor, and Robert Goodkin. "Thrombosis and hemorrhage in the acute period following Gamma Knife surgery for arteriovenous malformation." Journal of Neurosurgery 111, no. 1 (2009): 124–31. http://dx.doi.org/10.3171/2009.1.jns08784.

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Bleeding of an arteriovenous malformation (AVM) following stereotactic radiosurgery (SRS) is a known risk during the latency interval, but hemorrhage in the 30-day period following radiosurgery rarely has been reported in the literature. The authors present the case of a 57-year-old man who underwent Gamma Knife surgery for a large AVM, and they provide radiographic documentation of a thrombus in the primary draining vein immediately preceding an AVM hemorrhage within 9 days after radiosurgery. They postulate that the pathophysiology of an AVM hemorrhage in the acute period following SRS is re

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Stapf, C., J. P. Mohr, J. Pile-Spellman, R. R. Sciacca, A. Hartmann, and H. Mast. "The Effect of Concurrent Arterial Aneurysms on the Risk of Hemorrhagic Presentation in Brain Arteriovenous Malformations." Stroke 32, suppl_1 (2001): 337. http://dx.doi.org/10.1161/str.32.suppl_1.337-c.

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119 Background and Purpose: To assess the effect of concurrent arterial aneurysms on the risk of hemorrhagic presentation in brain arteriovenous malformations (AVMs). Methods: The 463 consecutive, prospectively enrolled patients from the New York AVM Databank were analyzed. Concurrent arterial aneurysms on brain angiography were classified as (1) flow-related feeding artery aneurysms, (2) intranidal aneurysms, and (3) aneurysms unrelated to blood flow to the AVM. Clinical presentation (diagnostic event) was categorized as (1) intracranial hemorrhage proven by imaging or (2) non-hemorrhagic pre

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Seymour, Zachary A., Penny K. Sneed, Nalin Gupta, et al. "Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm." Journal of Neurosurgery 124, no. 1 (2016): 163–74. http://dx.doi.org/10.3171/2014.12.jns141308.

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OBJECT Large arteriovenous malformations (AVMs) remain difficult to treat, and ideal treatment parameters for volume-staged stereotactic radiosurgery (VS-SRS) are still unknown. The object of this study was to compare VS-SRS treatment outcomes for AVMs larger than 10 ml during 2 eras; Era 1 was 1992-March 2004, and Era 2 was May 2004–2008. In Era 2 the authors prospectively decreased the AVM treatment volume, increased the radiation dose per stage, and shortened the interval between stages. METHODS All cases of VS-SRS treatment for AVM performed at a single institution were retrospectively rev

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Stapf, C., E. S. Connolly, J. Pile-Spellman, R. R. Siacca, H. Mast, and J. P. Mohr. "Dysplastic Vessels after Surgery for Brain Arteriovenous Malformations." Stroke 32, suppl_1 (2001): 358. http://dx.doi.org/10.1161/str.32.suppl_1.358-c.

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P107 Background and Purpose: To determine frequency and predictors of residual dysplastic vessels on cerebral angiography after surgery for brain arteriovenous malformation (AVM). Methods: The 240 prospectively enrolled surgical patients from the New York AVM Databank underwent 269 AVM-related surgical procedures between July-01, 1989 and June-30, 2000. Reported postoperative brain angiographic findings were classified post hoc as (1) normal, (2) persistent dysplastic vessels, (3) residual AVM, (4) focal hyperemia in the surgical bed, or (5) other changes. Univariate and multivariate models we

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Fukuda, Keiko, Monica Majumdar, Hesham Masoud, et al. "Multicenter assessment of morbidity associated with cerebral arteriovenous malformation hemorrhages." Journal of NeuroInterventional Surgery 9, no. 7 (2016): 664–68. http://dx.doi.org/10.1136/neurintsurg-2016-012485.

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BackgroundThe optimal management strategy for unruptured cerebral arteriovenous malformations (AVMs) is controversial since the ARUBA trial (A Randomized trial of Unruptured Brain AVMs). An accurate understanding of the morbidity associated with AVM hemorrhages may help clinicians to formulate the best treatment strategy for unruptured AVMs.ObjectiveTo determine the morbidity associated with initial cerebral AVM rupture in patients presenting to tertiary medical centers.MethodsRetrospective chart reviews from three tertiary academic medical centers were performed for the period between 2008 an

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Abdelaziz, Osama, Ahmed Shereen, Takuro Inoue, Hisao Hirai, and Ayako Shima. "Correlation of Appearance of MRI Perinidal T2 Hyperintensity Signal and Eventual Nidus Obliteration Following Photon Radiosurgery of Brain AVMs: Combined Results of LINAC and Gamma Knife Centers." Journal of Neurological Surgery Part A: Central European Neurosurgery 80, no. 03 (2019): 187–97. http://dx.doi.org/10.1055/s-0039-1678710.

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Background A wide variety of radiologic changes occur within and adjacent to the nidus of arteriovenous malformations (AVMs) after stereotactic radiosurgery (SRS). Our objective was to study the magnetic resonance imaging(MRI)-defined changes following photon radiosurgery of AVMs and specifically to correlate the appearance of a perinidal T2 hyperintensity signal with the eventual angiographic obliteration of an AVM nidus in response to SRS treatment. Material and Methods This retrospective study was conducted on 62 patients with brain AVMs who received photon SRS treatments between 2004 and 2

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Heit, Jeremy J., Abigail G. S. Faisal, Nicholas A. Telischak, Omar Choudhri, and Huy M. Do. "Headway Duo microcatheter for cerebral arteriovenous malformation embolization with n-BCA." Journal of NeuroInterventional Surgery 8, no. 11 (2015): 1181–85. http://dx.doi.org/10.1136/neurintsurg-2015-012094.

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BackgroundCerebral arteriovenous malformations (AVMs) are uncommon vascular lesions, and hemorrhage secondary to AVM rupture results in significant morbidity and mortality. AVMs may be treated by endovascular embolization, and technical advances in microcatheter design are likely to improve the success and safety of endovascular embolization of cerebral AVMs.ObjectiveTo describe our early experience with the Headway Duo microcatheter for embolization of cerebral AVMs with n-butyl-cyanoacrylate (n-BCA).MethodsConsecutive patients treated by endovascular embolization of a cerebral AVM with n-BCA

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Kim, Mooseong, Seyoung Pyo, Younggyun> Jeong, Sunil Lee, Yongtae Jung, and Haewoong Jeong. "Gamma Knife surgery for intracranial aneurysms associated with arteriovenous malformations." Journal of Neurosurgery 105, Supplement (2006): 229–34. http://dx.doi.org/10.3171/sup.2006.105.7.229.

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✓The incidence of aneurysms coexisting with arteriovenous malformations (AVMs) ranges between 2.7 and 16.7%. The anatomical relationship between the AVM and the aneurysm is critical in deciding the best management. As a broad guide, this relationship can be classified as follows: 1) aneurysms unrelated to the AVM; or 2) aneurysms located on the feeding vessels to the nidus, which may be far away from the nidus or close to it or even within the nidus itself. Although radiosurgery has been widely accepted as a method of choice for AVM treatment, the role of radiosurgery for arterial aneurysms ha

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Mizutani, Tohru, Hiroshi Tanaka, and Tohru Aruga. "Total recanalization of a spontaneously thrombosed arteriovenous malformation." Journal of Neurosurgery 82, no. 3 (1995): 506–8. http://dx.doi.org/10.3171/jns.1995.82.3.0506.

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✓ The authors describe what they believe to be the first case of an asymptomatic, totally recanalized arteriovenous malformation (AVM) demonstrated by angiography 31 months after complete spontaneous thrombosis. The AVM, which initially became symptomatic with bleeding, had a 2-cm diameter nidus that was located within the inferior aspect of the left frontal lobe and was fed by branches from the left anterior cerebral and anterior ethmoid arteries. A single draining vessel flowed from the nidus into the anterior superior sagittal sinus. The AVM was surgically extirpated after recanalization. T

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Kondziolka, Douglas, Robin P. Humphreys, Harold J. Hoffman, E. Bruce Hendrick, and James M. Drake. "Arteriovenous Malformations of the Brain in Children: A Forty Year Experience." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 19, no. 1 (1992): 40–45. http://dx.doi.org/10.1017/s0317167100042517.

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ABSTRACT:Despite the great capacity for the pediatric brain to recover from stroke, the morbidity and mortality in children who harbor an arteriovenous malformation (AVM) remains high. This study examines the clinical data and management experience with 132 patients with brain AVM from 1949 to 1989. Although the high tendency for a childhood AVM to present with hemorrhage (79%) remained constant for the forty year study period, the associated morbidity and mortality of hemorrhage changed. The mortality rate from hemorrhage for the entire series was 25%, which was reduced from 39% to 16% after

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Joo, S. "P.181 Surgical results with low-grade arteriovenous malformations: a single center 16-year experience." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 52, s1 (2025): S57. https://doi.org/10.1017/cjn.2025.10319.

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Background: Advancements in AVM surgical techniques for cerebral arteriovenous malformation (AVM) underscore its efficacy. Our research aims to showcase the positive outcomes of treating low-grade AVMs surgically, focusing on safety and effectiveness. Methods: We retrospectively reviewed 55 patients with Spetzler-Martin (S-M) grade 1 and 2 AVMs who underwent surgical resection between January 2009 and December 2024. Results: In our study, 55 patients with S-M grade 1 and 2 AVMs underwent surgical resection, evenly divided between grades 1 (50.9%) and 2 (49.1%). Intracranial hemorrhage was the

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Dmitriev, A. V., Sh Sh Eliava, S. B. Yakovlev, A. S. Kheyreddin, Yu V. Pilipenko, and Yu V. Strunina. "Complications and functional outcomes of microsurgical removal of arteriovenous malformations with preoperative endovascular embolization." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 6 (May 25, 2023): 408–16. http://dx.doi.org/10.33920/med-01-2306-03.

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Background. Brain arteriovenous malformations (AVMs) are the most complex pathology in vascular neurosurgery. Collecting and summarizing data on the results of brain AVM treatment is extremely important.Objective. Analysis of complications and functional outcomes of the AVM microsurgery with preoperative endovascular embolization. Material and methods. The study included 56 patients with brain AVMs who underwent preoperative embolization at the N.N. Burdenko National Medical Research Center of Neurosurgery. The control group included 113 patients who underwent only microsurgical removal of AVM

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Huo, Xiaochuan, Yuhua Jiang, Xianli Lv, Hongchao Yang, Yang Zhao, and Youxiang Li. "Gamma Knife surgical treatment for partially embolized cerebral arteriovenous malformations." Journal of Neurosurgery 124, no. 3 (2016): 767–76. http://dx.doi.org/10.3171/2015.1.jns142711.

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OBJECT A combination of embolization and radiosurgery is used as a common strategy for the treatment of large and complex cerebral arteriovenous malformations (AVMs). This study presents the experiences of partially embolized cerebral AVMs followed by Gamma Knife surgery (GKS) and assesses predictive factors for AVM obliteration and hemorrhage. METHODS The interventional neuroradiology database that was reviewed included 404 patients who underwent AVM embolization. Using this database, the authors retrospectively analyzed all partially embolized AVM cases followed by GKS for a residual nidus.

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Killory, Brendan D., Peter Nakaji, L. Fernando Gonzales, Francisco A. Ponce, Scott D. Wait, and Robert F. Spetzler. "PROSPECTIVE EVALUATION OF SURGICAL MICROSCOPE–INTEGRATED INTRAOPERATIVE NEAR-INFRARED INDOCYANINE GREEN ANGIOGRAPHY DURING CEREBRAL ARTERIOVENOUS MALFORMATION SURGERY." Neurosurgery 65, no. 3 (2009): 456–62. http://dx.doi.org/10.1227/01.neu.0000346649.48114.3a.

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Abstract OBJECTIVE Microscope-integrated indocyanine green (ICG) fluorescence angiography is a novel technique in vascular neurosurgery with potential utility in treating arteriovenous malformations (AVMs). METHODS We analyzed the application of intraoperative ICG in 10 consecutive AVM surgeries for which surgical video was available. The ability to distinguish AVM vessels (draining veins, feeding and nidal arteries) from each other and from normal vessel was evaluated, and ICG angiographic findings were correlated with intra- and postoperative findings on digital subtraction angiography (DSA)

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