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Journal articles on the topic 'Azadirachita indica'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Vijayavani, S. Ch, and Maravajhala Vidyavathi. "Azadirachita indica gum based sildenafil citrate mucoadhesive microspheres – Design and optimization." Journal of Drug Delivery Science and Technology 47 (October 2018): 499–513. http://dx.doi.org/10.1016/j.jddst.2018.08.011.

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2

Malviya, Rishabha, Pramod K. Sharma, and Susheel K. Dubey. "Characterization of Neem (Azadirachita indica) Gum Exudates Using Analytical Tools and Pharmaceutical Approaches." Current Nutrition & Food Science 15, no. 6 (2019): 588–99. http://dx.doi.org/10.2174/1573401314666180821150254.

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Background: Polysaccharide has been used as excipient in pharmaceutical and biomedical sciences. Objective: Objective of present research was to characterize crude Neem Gum Polysaccharide (NGP) for their possible applications in food, cosmetics and pharmaceutical industry. Methods: Purified NGP was characterized in terms of phytochemical screening, organoleptic properties, solubility, micromeritic properties, TLC analysis, ash value, microbial load, molecular confirmation, molecular weight, swelling behaviour, foaming ability, surface morphology, IR spectral analysis, 1H NMR and mass spectra a

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3

Malviya, Rishabha, Pramod Kumar Sharma, and Susheel Kumar Dubey. "Microwave Controlled the Green Synthesis of Acrylamide Graft Copolymers of Azadirachita indica Gum for the Wastewater Management." Current Applied Polymer Science 2, no. 2 (2018): 130–49. http://dx.doi.org/10.2174/2452271602666180517093813.

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Oluyege, J.O, A.J Olaleye, and A.O Oluyege. "ANTIBACTERIAL EFFECT OF SOME NIGERIAN MEDICINAL PLANTS ON DRUG- RESISTANT SALMONELLA SPECIES ISOLATED FROM ENVIROMENTAL SOURCES." Continental J. Microbiology 4 (July 7, 2010): 25–30. https://doi.org/10.5281/zenodo.823813.

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Sensitivity of <em>Salmonella</em> species isolated from different environmental sources to the extracts of <em>Azadirachita indica</em>, <em>Psdium guajava</em>, <em>Kigelia africana</em> and <em>Aloe microcarpa</em> was investigated. Susceptiblity of the isolates to amoxicillin, ofloxacin, tetracycline, gentamicin, nalixidic acid, nitrofuratoin and cotrimoxazone was also examined. The sensitivity assay was done using agar dilution technique at concentrations ranging from 0.5 to 20% v/v. The concentration of all the extracts of the experimental plants that inhibited the growth of <em>Salmonel

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Qodri, Udrika Lailatul. "Uji Organoleptik Serbuk Biji Azadirachta Indica Dalam Variasi Minyak." Jurnal Farmasi Tinctura 1, no. 1 (2019): 26–33. http://dx.doi.org/10.35316/tinctura.v1i1.778.

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Neem plants (Azadirachta indica) are commonly found in Situbondo Regency, and currently underutilized nimba plants have many benefits, both in agriculture as pesticides and in pharmaceuticals as medicines. The content of the active compound is more commonly found in nimba seeds. The largest active compound that is an insecticide in neem seeds (Azadirachta indica) is azadirachtin. Azadirachtin is a group of terpenoid compounds which are generally non-polar so that the extraction process can use non-polar solvents. In this study using oil as a carrier solvent, it is known that oil is non-polar.

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Dida, Mulisa Faji, Alayu Tarekegn Beyene, and Habtamu Alebachew Damtew. "Does Azadirachita indica leaves, Stylosanthes fruticosa and Dolichus lablab substitute conventional concentrate mixture: Evidence from the sheep feeding trial." Journal of Agriculture and Food Research 12 (June 2023): 100591. http://dx.doi.org/10.1016/j.jafr.2023.100591.

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7

A.S., Mohite, and Dorlikar A.V. "Growth Regulating Effects of Natural Pesticide, Azadirachtin from Neem Tree (Azadirachta indica A. Juss) on Insects: A Review." International Journal of Zoological Investigations 08, no. 02 (2022): 774–83. http://dx.doi.org/10.33745/ijzi.2022.v08i02.093.

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Azadirachtin is a tetranortriterpenoid derived from the neem tree Azadirachta indica A. juss. Azadirachtin has attracted worldwide attention as promising feeding deterrent, insect growth disruptor and sterilent. Azadirachtin based pesticides become very much popular because of its biodegradability and least toxicity to non- target organisms. It has now been promoted as an alternative insecticide in integrated pest management programmes. Azadirachtin has an ability to modify or suppress haemolymph ecdysteroid and juvenile hormone titres through inhibition of the secretion of brain peptides prot

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Loganathan, T., A. Barathinivas, C. Soorya, et al. "Physicochemical, Druggable, ADMET Pharmacoinformatics and Therapeutic Potentials of Azadirachtin - a Prenol Lipid (Triterpenoid) from Seed Oil Extracts of Azadirachta indica A. Juss." Journal of Drug Delivery and Therapeutics 11, no. 5 (2021): 33–46. http://dx.doi.org/10.22270/jddt.v11i5.4981.

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Azadirachtin (AZA) is the most abundant bioactive secondary metabolite (BASM) in neem seed oil extract (NSOE) of Azadirachta indica A. Juss. AZA is localised in different parts of the plant (seeds, fruits, flowers, leaves, stem, bark and root) however, with varying degree of concentration. It has been documented that maximum concentration of AZA is present to the tune of 48000 μg g-1 in the seeds. It has been established that the environmental conditions determines the overall content and composition of BASM in different parts of the plant. Neem plant parts are most commonly used as therapeuti

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9

Saurish, Sarkar. "Callus culture of Azadirachta indica employing its stem." International Journal of Trend in Scientific Research and Development 2, no. 3 (2018): 318–23. https://doi.org/10.31142/ijtsrd10911.

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Azadirachtin,an insecticidal active ingredient present in neem tree i.e.Azadirachta indica A. Juss.seeds and they varies considerably due to environmental factors also for genetic reasons. Furthermore, the tree does not grow in moderate climates and their germination ratio is very less. It seems appropriate, therefore, to employ tissue culture techniques for the production of Azadirachtin in order to obtain constant amounts of standardized quality. Here we try to create callus, an unspecialized, unorganized, growing and dividing mass of cells through which mass cultivation further initiate. Th

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10

Das, Rajesh Kumar. "A Comparative Study of Antidiabetic Activity of Azadirachta Indica, Aloe Vera and Allium Cepa." International Journal for Research in Applied Science and Engineering Technology 10, no. 6 (2022): 1119–30. http://dx.doi.org/10.22214/ijraset.2022.43975.

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Abstract: Extract from medicinal plants are widely used to prevents various diseases due to presence of lots of phytochemicals. The extracts from different parts like leaf, stem, fruit, flower, bark, root of Azadirachta indica, Aloe vera and Allium cepa shows lots of pharmacological activity. Antidiabaetic property is most important of them. Various parts of Azadirachta indica, Aloe vera and Allium cepa were largely used in Ayurveda, Unani and Siddha medicines. Chemical investigation on all three plants explore the presence of different types of active compounds like azadirachtin , nimbolinin,

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11

Parasuraman, P., Suresh R, and Perumal P. "SEARCHING ANTIVIRAL DRUGS FOR EBOLA VIRUS FROM PHYTO-CONSTITUENTS OF AZADIRACHTA INDICA: APPLICATION OF MOLECULAR MODELING STUDIES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 7 (2017): 254. http://dx.doi.org/10.22159/ajpcr.2017.v10i7.17500.

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ABSTRACTThe current objective of the study is to identify some naturally occurring product from Azadirachta indica and evaluate its binding activity against VP24 protein as Ebola virus target through in silico docking studies. Reported phytoconstituents of Azadirachta indica were prepared for docking evaluation using Brincidofovir as the standard. In silico docking studies were carried out using GLIDE (Grid-based Ligand Docking with Energetics) is a ligand binding program provided by Schrödinger. These results showed that all the selected phytoconstituents showed binding energy ranging between

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12

Paula, Joelma Abadia Marciano de, Gabriel Luis Castiglioni, Lucas Ferreira Brito, Aline Mar Rodrigues da Silva, Debborah Gonçalves Bezerra, and Edemilson Cardoso da Conceição. "Mechanical Drying of Azadirachta Indica A. Juss. seeds: a Tool to Keep Quality of this Eco-Friendly Bio-Insecticide." Fronteiras: Journal of Social, Technological and Environmental Science 11, no. 1 (2022): 39–44. http://dx.doi.org/10.21664/2238-8869.2022v11i1.p39-44.

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Products based on Azadirachta indica A. Juss. (Meliaceae) seeds are worldwide renowned as eco-friendly bio-insecticides. However, the improper processing of the seed may cause significant losses in product effectiveness, as the contents of azadirachtin – its main component – may be affected. This paper aims to assess the degradation level of azadirachtin found in A. indica seeds during the kiln drying process under different temperature and airflow conditions. In order to do so, samples of A. indica fresh seeds were crushed and subjected to 11 drying assays in temperatures ranging from 55 °C t

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13

Oludayo, Olaniyi Christianah, Fawole Olaolu Olalekan, and Awogbade Adeniyi Adediran. "The Significance of Processing Techniques on the Quality of Smoked African Cat Fish (Clarias gariepinus) Using Different Energy Sources." Asian Journal of Fisheries and Aquatic Research 26, no. 5 (2024): 82–89. http://dx.doi.org/10.9734/ajfar/2024/v26i5768.

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There is unavoidable need for fish smoking as a preservative technique to reduce rampant post harvest losses in the tropical Africa. However the imperative of healthier and quality smoked products through improved processing method were however investigated. Organoleptic and chemical assessment of African catfish collected from a reputable fish farm in Ogbomoso, Oyo state Nigeria was carried out. Eviscerated and non-eviserated fish samples were smoked using four different smoke sources: Gmelina (Gmnelina arborea), Parkia (Parkia biglobosa), Neem (Azadirachita indica) and charcoal. Overall acce

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14

Wijaya, Natalia, and Gusti Agung Ayu Sriyani. "Effectiveness of Azadirachta indica and Ocimum gratissimum for Acne Vulgaris: A Literature Review." International Journal of Research and Review 11, no. 10 (2024): 1–7. http://dx.doi.org/10.52403/ijrr.20241001.

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Acne vulgaris is a common dermatological condition characterized by inflammation of the pilosebaceous units, predominantly affecting adolescents and young adults. Its multifactorial etiology involves hormonal imbalances, microbial overgrowth, and environmental factors, leading to increased sebum production and inflammation. Conventional treatments often vary in efficacy and tolerability, driving interest in alternative therapies to reduce the severity and recurrence of lesions and enhance appearance, the acne severity. This literature review explores the therapeutic potential of two herbal rem

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15

Sonal Balasaheb Bangar, Shreya Sandeep Bankar, Aditi Sunil Vibhute, et al. "Review on therapeutic approach of anti-acne treatment by Azadirachta indica and Ocimum gratissimum." World Journal of Advanced Research and Reviews 22, no. 2 (2024): 165–74. http://dx.doi.org/10.30574/wjarr.2024.22.2.1268.

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Millions of people worldwide suffer with acne vulgaris, a common skin ailment marked by the development of comedones, papules, pustules, and in more severe cases, nodules and cysts. There has been a boom in research into alternative remedies, especially herbal pharmaceuticals, due to growing resistance to traditional therapy and side effects associated with long-term use. Two well-known herbs with strong anti-acne effects are Ocimum gratissimum (scent leaf/ African basil) and Azadirachta indica (neem). The purpose of this review is to assess Azadirachta indica and Ocimum gratissimum's medicina

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16

Raikwar, Umesh Kumar, Akanksha Singh, and Surabhi Yadav. "Azadirachta Indica (Neem) in Traditional Indian Medicine: Indigenous Knowledge & Scientific Validation." International Journal of Research and Scientific Innovation XII, no. V (2025): 1334–41. https://doi.org/10.51244/ijrsi.2025.120500127.

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Neem, scientifically known as Azadirachta indica, has been an integral part of human history for millennia, especially in the Indian subcontinent. Its significance in ancient times can be seen in various aspects such as traditional, medicinal and cultural. Neem’s versatility and wide range of usage made it an invaluable resource since ancient time. Its legacy continues to be celebrated in modern times for its numerous benefits. Bark, leaves, and roots contain Antimicrobial, Antifungal, Insecticidal, Antiviral, Anti-Malarial, Antiperiodic, Mosquito Larvicidal, Anti-Inflammatory, Antifertility,

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JOY, JOSNA, MADAPPA MAHESH, SHIVANNEGOWDA MAHADEVAKUMAR, et al. "Cytospora azadirachtae sp. nov.—A new species associated with dieback disease in Azadirachta indica from southern India." Phytotaxa 670, no. 1 (2024): 43–54. http://dx.doi.org/10.11646/phytotaxa.670.1.4.

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Stem cankers associated with dieback disease of neem (Azadirachta indica) shoots were collected from Manasagangotri and Doddamaragowdanahalli, Mysore, Karnataka (India) and based on microscopic, cultural and initial blast results of ITS-rDNA identified the isolated fungus to the genus Cytospora. The phylogenetic analysis based on nrITS-rDNA-tef1-α-tub2 sequence data showed it represents a new species and is described as Cytospora azadirachtae. The concatenated phylogeny revealed that Cytospora azadirachtae is phylogenetically distinct and closely related to Cytospora shoreae and C. rhizophorae

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18

Mat Zaib, Nik Amalia Nasratiena, Saiyidah Nafisah Hashim, Wan Rozianoor Mohd Hassan, and Chia Chay Tay. "Molluscicidal Activity and Inhibition of Acetylcholinesterase Activity of Azadirachta Indica Extract on Pomacea Canaliculata." Sains Malaysiana 53, no. 5 (2024): 1081–91. http://dx.doi.org/10.17576/jsm-2024-5305-09.

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The Golden Apple Snail, Pomacea canaliculata, is a notorious pest in Malaysia, leading to substantial agricultural and economic losses, while, the neem tree, Azadirachta indica has been identified as alternative source for bio-pesticides. There is currently limited information on A. indica as natural molluscicide against P. canaliculata. This study aims to evaluate the effects of A. indica on P. canaliculata at various life stages (eggs, juvenile and adult). The bioactive compound, azadirachtin in A. indica extracts was quantified using high-performance liquid chromatography (HPLC). Egg hatcha

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Joy, Josna, Madappa Mahesh, Shivannegowda Mahadevakumar, Sajeewa S. N. Maharachchikumbura, Siddaiah Chandranayaka, and Thanuku Samuel Sampath Kumar Patro. "Cytospora azadirachtae sp. nov.-A new species associated with dieback disease in Azadirachta indica from southern India." Phytotaxa 670, no. 1 (2024): 43–54. https://doi.org/10.11646/phytotaxa.670.1.4.

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Joy, Josna, Mahesh, Madappa, Mahadevakumar, Shivannegowda, Maharachchikumbura, Sajeewa S. N., Chandranayaka, Siddaiah, Patro, Thanuku Samuel Sampath Kumar (2024): Cytospora azadirachtae sp. nov.-A new species associated with dieback disease in Azadirachta indica from southern India. Phytotaxa 670 (1): 43-54, DOI: 10.11646/phytotaxa.670.1.4, URL: https://doi.org/10.11646/phytotaxa.670.1.4

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Huang, Qiu-Rong, Indunil C. Senanayake, Jia-Wei Liu, Wen-Jing Chen, Zhang-Yong Dong, and Mei Luo. "Trichoderma azadirachtae sp. nov. from rhizosphere soil of Azadirachta indica from Guangdong Province, China." Phytotaxa 670, no. 3 (2024): 148–60. https://doi.org/10.11646/phytotaxa.670.3.1.

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Huang, Qiu-Rong, Senanayake, Indunil C., Liu, Jia-Wei, Chen, Wen-Jing, Dong, Zhang-Yong, Luo, Mei (2024): Trichoderma azadirachtae sp. nov. from rhizosphere soil of Azadirachta indica from Guangdong Province, China. Phytotaxa 670 (3): 148-160, DOI: 10.11646/phytotaxa.670.3.1, URL: https://doi.org/10.11646/phytotaxa.670.3.1

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Devi, Jyoti, and Ram Babu Sharma. "Medicinal Importance of Azadirachta indica: An Overview." Journal of Drug Delivery and Therapeutics 13, no. 6 (2023): 159–65. http://dx.doi.org/10.22270/jddt.v13i6.5992.

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Background: The neem tree has a long history of being referred to as a "wonder tree." Since the time of the Vedic civilization, neem has been used therapeutically in many different ways in India. The various components of the neem tree, including the stem, bark, roots, leaves, gum, seeds, fruits, and flowers, have a no. of chemical constituents and have been used as traditional medicines. The seeds, leaves, blossoms, and bark of this tree, are used for treating various diseases. Since ancient times, neem tree extracts have been widely employed in health management because they possess a number

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Ramji, Niranjan, K. Venkatakrishnan, and K. M. Madyastha. "11-Epi-azadirachtin H from Azadirachta indica." Phytochemistry 42, no. 2 (1996): 561–62. http://dx.doi.org/10.1016/0031-9422(96)00014-3.

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23

Jurášek, Michal, and Pavel Drašar. "Sarva Roga Nivarini, Gift of the Gods." Chemické listy 118, no. 9 (2024): 475–77. http://dx.doi.org/10.54779/chl20240475.

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The article deals with the Azadirachta indica tree, called neem, which, as well as its products, is used in traditional medicine, agrochemicals, as a source of biologically active substances, but also as part of food. It describes the main chemical components, namely azadirachtin. Full text English translation is available in the on-line version.

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Sonal, Balasaheb Bangar, Sandeep Bankar Shreya, Sunil Vibhute Aditi, et al. "Review on therapeutic approach of anti-acne treatment by Azadirachta indica and Ocimum gratissimum." World Journal of Advanced Research and Reviews 22, no. 2 (2024): 165–74. https://doi.org/10.5281/zenodo.14550444.

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Millions of people worldwide suffer with acne vulgaris, a common skin ailment marked by the development of comedones, papules, pustules, and in more severe cases, nodules and cysts. There has been a boom in research into alternative remedies, especially herbal pharmaceuticals, due to growing resistance to traditional therapy and side effects associated with long-term use. Two well-known herbs with strong anti-acne effects are <em>Ocimum gratissimum </em>(scent leaf/ African basil) and <em>Azadirachta indica </em>(neem). The purpose of this review is to assess <em>Azadi

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Ramji, Niranjan, Krishnamachari Venkatakrishnan, and K. M. Madyastha. "11-epi-azadirachtin D: an epimeric azadirachtin analogue from azadirachta indica." Phytochemistry 49, no. 1 (1998): 265–67. http://dx.doi.org/10.1016/s0031-9422(97)01009-1.

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Oktadiana, Isma, and Venny Diah Ningsih. "Aktivitas Penolak Serangga (Insect Repellent) Ekstrak Klorofom Biji Mimba (Azadirachta Indica) Terhadap Kutu Beras (Calandra Oryzae)." Jurnal Farmasi Tinctura 1, no. 2 (2020): 55–63. http://dx.doi.org/10.35316/tinctura.v1i2.989.

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Plants that are currently being developed as botanical insecticides are those that produce essential oils. The largest active compound that is insecticidal in neem (Azadirachta indica) is azadirachtin, this compound belongs to the triterpenoid group. The purpose of this study was to determine the level of insect repellent activity of neem (Azadirachta indica) seed chlorophome extract against rice lice (Calandra oryzae). This research is an experimental study using a completely randomized design (CRD). Consisting of neem seed extract treatment with a concentration of 0.1% and 0.5% and a control

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Kanthavelkumaran, N., and P. Seenikannan. "Experimental Studies on Performance and Emission Analysis in Diesel Engine Using Bio-Fuel (Neem Oil)." Advanced Materials Research 768 (September 2013): 255–61. http://dx.doi.org/10.4028/www.scientific.net/amr.768.255.

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In present scenario Bio-fuel act as the major role in todays fuel compensation. In India Neem tree is a broadly grown up termed as a divine tree due to its large revalance in many areas of study. The current research study is projected to consider aspect related to the possibility of preparation of Biodiesel from Neem oil. This research deals with Biodiesel preparation from neem oil, which is mono ester prepared using transesterification process. Biodiesel is a safe substitute fuel to replace established petroleum diesel. It has maximum lubricity is a clean burning fuel and can be a fuel compo

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Fatima, Gulzar, Aleza Moqaddas, and Madiha Lateef. "Cross-Linking Biotechnology and Pharmaceutical Biochemistry Insights: Investigating Medicinal Potential in Azadirachta Indica, Swietenia Mahagoni and Melia Azedarach." Journal of Health and Rehabilitation Research 4, no. 2 (2024): 376–81. http://dx.doi.org/10.61919/jhrr.v4i2.806.

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Background: The increasing resistance to synthetic drugs and their side effects has prompted renewed interest in the medicinal potential of natural products. Azadirachta indica, Swietenia mahagoni, and Melia azedarach, members of the Meliaceae family, have been traditionally used for their diverse therapeutic properties. Their efficacy stems from a range of bioactive compounds known for antifungal, antiviral, antibacterial, and anti-inflammatory activities. Objective: This study aims to explore and quantify the bioactive compounds in Azadirachta indica, Swietenia mahagoni, and Melia azedarach,

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Seydou, BADIANE Thierno, NDIONE Raymond Demba, Mamour TOURE, Fawrou SEYE, and Mady Ndiaye. "Larvicidal and Synergic Effects of two Biopesticides (Azadirachta indica and Metarhizium anisopliae) against Larvae of Culex quinquefasciatus (Diptera, Culicidae) (Say, 1823)." International Journal of Sciences Volume 6, no. 2017-04 (2017): 109–15. https://doi.org/10.5281/zenodo.3349811.

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Mosquitoes in general and Culex quinquefasciatus in particular have for a long time constituted a source of nuisance due to the diseases they transmit, stings and annoying buzzing. They are also a public health problem. This is why this study is aimed at finding a biopesticide that can fight effectively but also be an alternative to chemical residual pesticides in the environment. Concentrations of biopesticides used are ranged from 2.5 108 to 12.5 108 spores/ml with intervals of 2.5 108 spores/ml for Metarhizium anisopliae. Concentrations ranging beetween 8 10-4g/ml to 40 10-4 g/ml with inter

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Harbans, Singh, Palewar Sarang, Palewar Chetna, and Kumar Sunil. "The Therapeutic Potential of Dykure Capsule in Diabetes." Chemistry Research Journal 9, no. 1 (2024): 69–75. https://doi.org/10.5281/zenodo.11275177.

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<strong>Abstract </strong> This study investigates the management of diabetes of poly herbal formulation dykure capsule which contains <em>Azadirachata Indica, Trigonalia Foenumgraecum, Ficrochiza Kurroa, Terminalia Chrbula, Saraca Indica, Madhuca Indiaca, Coccinia Indica, Momoxdica Charantica, Asphaltum, Abitilon Indica, Tinospora Cardifolia, Terminilia Balerica</em> and <em>Aerva Lanota</em>. This herbal formulation has not shown any harmful side effects on the patients. To ascertain the long-term effect of the medicine, a farther clinical trial of Dykure Capsule is needed for a period betwe

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Sharma, Aarju, Ashwani Kumar, Sulekha Chahal, and Bindu Battan. "Enhancing sandalwood growth: Host plant selection and salinity stress tolerance." Journal of Applied Horticulture 26, no. 02 (2024): 262–67. http://dx.doi.org/10.37855/jah.2024.v26i02.50.

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Being a semi-root parasitic nature, sandalwood steals water and nutrients from host species. Therefore, it is crucial to research the influence of salinity stress on host-parasite relationships both theoretically and practically, for the successful establishment of sandalwood plantations. To find out the best suited host species for sandalwood, a RBD experiment was conducted to identify the effect of salt stress on sandalwood planted with two selected host species (Alternanthera sp. and Azadirachata indica) and without host species. After 300 days of establishment, morphological traits were re

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Binita, Oli, and Gautam Deepak. "Medicinal value of Azadirachta indica: A review." Modern Phytomorphology 15, no. 6 (2022): 161–67. https://doi.org/10.5281/zenodo.7731409.

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Nature has been a great source of therapeutic compounds. The use of plants and plant-derived products as medicine has been a popular tradition as the beginning of human civilization. Plants are considered as the richest source of traditional and modern medications as well as food supplements, pharmaceutical intermediates and chemical entities for synthetic drugs. Among them, Azadirachta indica is one of the most versatile, multitudinous tree having immense potentials. Since Vedic times, it has been known as the multi-directional therapeutic uses in India. It is economically cheaper and safe an

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Ul Haq, Syed Imran, Tribhuvan Singh, Shaik Mohammed Salman, Afifa Namreen, and Anas Rasheed. "Analytical Method Validation of Azadirachtin Extracted From Azadirachta Indica." INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 2, no. 04 (2017): 99–106. http://dx.doi.org/10.21477/ijapsr.v2i04.9552.

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A simple UV spectrophotometric method for the determination of Azadirachtin is developed exhibiting maximum absorbance using distilled water at 542nm.The present study is based on the detection of sample drug concentration using dichloro methane as diluent. All the conditions required were optimized. Statistical analysis was carried out and results of which were satisfactory. The optical characteristics such as absorption maxima, regression analysis and correlation coefficient are obtained. Recovery studies were close to 100% that indicate the accuracy and precision of proposed method and the

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Kauser Perveen. "Neem's promise: The way to a sustainable future and eco-friendly biopesticides." International Journal of Science and Research Archive 11, no. 2 (2024): 1073–82. http://dx.doi.org/10.30574/ijsra.2024.11.2.0532.

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Modern agriculture must include pest management since pests can seriously harm crops and lower yields, resulting in considerable financial losses. Conventional chemical insecticides have been used as the main method of pest management, but their detrimental effects on the environment and human health have inspired the quest for new environmentally friendly options. In this situation, Azadirachta indica showed promise as a sustainable and eco-friendly biopesticide. This research shows many aspects for Azadirachta indica as an environment friendly biopesticide. Neem is well known for having anti

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FALANA, Mansurat B., and Quadri O. NURUDEEN. "Analysis of secondary metabolites and in vitro evaluation of extracts of Carica papaya and Azadirachta indica leaves on selected human pathogens." Notulae Scientia Biologicae 12, no. 1 (2020): 57–73. http://dx.doi.org/10.15835/nsb12110541.

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Extraction of the leaves of Carica papaya (family Caricaceae) and Azadirachta indica (family Meliacea) were done using solvents with varying polarities (acetone, hexane and ethylacetate). The crude extracts were screened for phytoconstituents using the preliminary method and high-performance liquid chromatography (HPLC) for separation and quantification of the constituents. Susceptibility of three medically important microorganisms (Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 and Candida alblicans) to the solvent extracts was tested at 100 mg/mL, 50 mg/mL and 25 mg/mL concent

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Samiksha, Thorat* Ashok jagdale. "Azadirachtin Indica: A Potential Substance with Anti-Cancer Properties and Activities." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 566–78. https://doi.org/10.5281/zenodo.14278587.

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Neem, or Azadirachta indica, is a plant that is native to the Indian subcontinent and is a member of the Meliaceae family. Because of its many biological benefits, the Neem tree is also known as the village pharmacy. There are several applications for every part of the Neem tree, including its bark, leaves, sap, fruit, seeds, and twigs. They are commonly used to treat a variety of infections and skin conditions Azadirachtin and nimbolide are among the few bioactive components in neem that have been studied extensively, but research on a great number of additional bioactive components is warran

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Demolin-Leite, G. L., A. Juss., The Importance Indice, Each A., Fried Trace Elements, and Sewer Treatment Station. "Arthropods on Azadirachta indica A. Juss. (Sapindales: Meliaceae) saplings." Brazilian Journal of Biology 82 (December 31, 2022): 1–4. https://doi.org/10.1590/1519-6984.263551.

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Demolin-Leite, G. L., Juss., A., Indice, The Importance, A., Each, Elements, Fried Trace, Station, Sewer Treatment (2022): Arthropods on Azadirachta indica A. Juss. (Sapindales: Meliaceae) saplings. Brazilian Journal of Biology (e263551) 82: 1-4, DOI: 10.1590/1519-6984.263551, URL: http://dx.doi.org/10.1590/1519-6984.263551

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Assiry, Ali A., Shaeesta Khaleelahmed Bhavikatti, Fahad A. Althobaiti, Roshan Noor Mohamed, and Mohmed Isaqali Karobari. "Evaluation of In Vitro Antiprotease Activity of Selected Traditional Medicinal Herbs in Dentistry and Its In Silico PASS Prediction." BioMed Research International 2022 (June 6, 2022): 1–8. http://dx.doi.org/10.1155/2022/5870443.

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Background. Dental/oral diseases are one of the significant public health problems globally. Herbal medicines for managing oral diseases are considered an effective alternative to synthetic compounds due to their lower side effect. Azadirachta indica, Terminalia chebula, Camellia sinensis, and Piper nigrum are used to control and prevent oral inflammations in dentistry. In this study, we have evaluated the protease inhibition activity of these plant extracts, and further, the binding mode of the active ingredient of these plants with trypsin was studied using molecular docking. Methods. In thi

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CHIJIOKE OZIOKO, PAUL, UKAMAKA OWOHETETE, and DANIEL DANLADI GAIYA. "DRUGGABILITY AND MOLECULAR DOCKING OF ESSENTIAL SECONDARY METABOLITES FROM Azadirachta indica LEAF AGAINST ANGIOTENSIN CONVERTING ENZYME-2: COVID-19 IN FOCUS." AFRICAN JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT 16, no. 3 (2024): 12–24. https://doi.org/10.59493/ajopred/2024.3.3.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious and virulent coronavirus that arose in late 2019 and poses great risk to public health and safety. The SARS-CoV-2 utilizes peptidase, angiotensin-converting enzyme 2 (ACE2) for entrance and invasion into host cells. Thus, this study explored the in-silico druggability and molecular docking of essential secondary metabolites (ESMs) from Azadirachta indica leaf as potential inhibitors of ACE-2, a main receptor for the SARS-CoV-2 virus causing the COVID-19 pandemic. Through a literature survey and database mining

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Fawole, Olaolu O., and Christianah O. Olaniyi. "Effects of fuel sources on organoleptic characteristics, polycyclic aromatic hydrocarbon concentration and shelf life of smoked Nile tilapia (Oreochromis niloticus)." Archives of Ecotoxicology 6, no. 2 (2024): 37–41. http://dx.doi.org/10.36547/ae.2024.6.2.37-41.

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This study assessed the effect of four different fuel sources on the organoleptic properties, polycyclic aromatic hydrocarbon concentration (PAH) and shelf-life of smoked Nile tilapia (Oreochromis niloticus). Dry wood of Gmelina (Gmelina arborea), Parkia (Parkia biglobosa), Neem (Azadirachita indica) and charcoal were obtained around Ladoke Akintola University of Technology, Ogbomoso, Oyo state. Nile tilapia samples were smoked to complete dryness using the four fuel sources. Data were analyzed using descriptive statistics and ANOVA at p<0.05. The organoleptic assessment of smoked fish show

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Ramdas, Miss Lavhale Harshada. "Formulation of Herbal Gel for Wound Healing from Hollarrhena Pubences, Withania Somnifera, Azadirachta Indica, Curcuma Longa." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (2021): 1128–33. http://dx.doi.org/10.22214/ijraset.2021.39488.

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Abstract: The present reaearch has been undertaken with the aim to fomulate and evaluate the herble gel containng alcoholic extract of Hollarrhena pubences(kurchi), Withania somnifera(ashwagandha), curcuma longa(turmeric)Azadiracht indica(neem). The gel formulation prepared by using various polymer bases(methyl cellulose) . The stability study have carried as perICH guideline. The result show that the gel formulation containing kurchi, ashwagandha, turmeric, neem has better stability than other. All formulation studied on animal model(rat).The present work justifies the use oh herbal gel conta

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Ashok, Borude Sanket, Prof Priyanka Vitthal Jadhav, and prof Ajay Baburao Shirsa. "Azadirachta indica: A Medicinal Plant with Many Uses for Immunity, Cancer, and Digestive Disorders." International Journal of Pharmaceutical Research and Applications 09, no. 05 (2024): 431–34. https://doi.org/10.35629/4494-0905431434.

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Azadirachta indica, a tropical plant widely used for its many therapeutic uses, is also referred to as neem. This review focuses on how it may help with digestive issues, cancer prevention and treatment, and immunity enhancement. The plant’s bioactive substances, such as azadirachtin, nimbin, and nimbolide, have anticancer, immunomodulatory, and gastroprotective properties. Research reveals that neem can boost immunity, cause cancer cells to undergo apoptosis, and lessen gastrointestinal tract irritation. Its potential for medicinal use is further enhanced by its antioxidant and antibacterial

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Su, Xinyao, Zhipeng Liang, Qiang Xue, Jia Liu, Xuemi Hao, and Caixia Wang. "A comprehensive review of azadirachtin: physicochemical properties, bioactivities, production, and biosynthesis." Acupuncture and Herbal Medicine 3, no. 4 (2023): 256–70. http://dx.doi.org/10.1097/hm9.0000000000000086.

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Azadirachtin, a complex tetratriterpenoid limonin with potent insecticidal properties, is the most widely used biological pesticide worldwide. Its versatile pharmacological applications include the inhibition of tumor growth and anti-malarial, anti-bacterial, and anti-inflammatory properties. Azadirachtin plays a pivotal role in pest control and novel drug development. The primary source of azadirachtin is the neem tree (Azadirachta indica A. Juss), with an azadirachtin content ranging from 0.3% to 0.5%. Despite the market demand for botanical pesticides reaching approximately 100,000 tons per

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Govindachari, T. R., Geetha Gopalakrishnan, S. S. Rajan, V. Kabaleeswaran, and L. Lessinger. "Molecular and crystal structure of azadirachtin-H." Acta Crystallographica Section B Structural Science 52, no. 1 (1996): 145–50. http://dx.doi.org/10.1107/s0108768195010056.

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Azadirachtin-H, isolated from the seed kernels of Azadirachta indica (neem), crystallizes in space group I4, Z = 8, with disordered ethyl acetate solvent filling channels along the fourfold rotation axes. The crystal structure determination showed that the previously reported molecular structure deduced from NMR studies was correct except for the stereochemistry at C(11). Azadirachtin-H, which belongs to a group of C-seco-tetranortriterpenoids (C-seco-limonoids) of great interest for their insect antifeedant and ecdysis-inhibiting activity, has some unusual features: the absence of a carbometh

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Pradhan, Yashashree, Hari Prasad Devkota, and Ahmad Ali. "Potential Role of Medicinal Plants and their Phytochemicals against Plaque forming Oral Microbiota." Biosciences Biotechnology Research Asia 21, no. 2 (2024): 371–89. http://dx.doi.org/10.13005/bbra/3232.

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Dental plaque, a type of biofilm formed on the tooth surface, is one of the most common dental problems suffered by many individuals all over the world. Various mechanical methods are used to remove plaque and certain chemical agents are used for prevention from dental plaque formation. Though these agents have fast action, long term use of synthetic agents may cause certain side effects. People around the world have been using medicinal plants for oral health care from hundreds of years. Some of such plants that are used in the prevention of dental plaques are Ocimum basilicum, Azadirachta in

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T., Leon Stephan Raj, Vijayakumari J., and Menaga M. "Azadirachta Indica A. Juss. Leaf Extract Mediated Synthesis of Silver Nanoparticles and their Antibacterial Efficacy Against Selected Human Pathogens." International Journal of Trend in Scientific Research and Development 2, no. 5 (2018): 1199–204. https://doi.org/10.31142/ijtsrd16986.

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The present study deals with the biological synthesis of silver nanoparticles AgNPs from the leaves of Azadirachta indicia and their efficacy against human pathogens. Azadirachta indicia has the potent medicinal properties and used in different aspects of traditional medicines. The presence of silver nanoparticles was confirmed by the formation of brown color of the reaction mixture. The green synthesized silver nanoparticles were characterized by Fourier transmission infrared spectroscopy FT IR analysis and X ray diffraction XRD . FT IR revealed that the functional groups were observed and ca

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Santiago, Magda Regina. "Toxicidade aguda de pesticida à base de Nim (Azadirachta indica A Juss) de uso em jardinagem e agricultura ao zebrafish (Danio rerio Hamilton-Buchanan)." Brazilian Journal of Animal and Environmental Research 7, no. 4 (2024): e75773. https://doi.org/10.34188/bjaerv7n4-124.

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As sementes de Nim (Azadirachta indica) contém muitos metabólitos secundários, sendo o limonóide azadirachtina, o mais importante. As propriedades inseticidas do Nim são conhecidas no controle de pragas. A ABNT (2010) preconiza o zebrafish (Danio rerio) como organismo para testes de substâncias químicas e biomonitoramento ambiental e o objetivo deste experimento foi avaliar a ecotoxicidade de inseticida à base de A.indica aquele organismo. O produto testado foi o Sempre Verde Killer – Linha Ecológica, com concentração declarada ne rótulo de 0,30% de azadirachtina. Os resultados ratificam que o

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KUMAR, ASHOK, R. SWAMINATHAN, M. K. MAHLA, et al. "Efficacy of Bio-rational insecticides against Perilla leaf moth on sweet basil (Ocimum basilicum)." Indian Journal of Agricultural Sciences 92, no. 5 (2022): 529–32. http://dx.doi.org/10.56093/ijas.v92i5.124763.

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The present study was carried out during kharif 2016–18 at Agronomy Farm, Rajasthan College of Agriculture, MPUAT, Udaipur. The Perilla leaf moth, Pyrausta panopealis Walker (Lepidoptera: Pyralidae) is an important and major insect pest of sweet basil, therefore, ecofriendly bio-rational insecticides were evaluated against perilla leaf moth in the present experiment. The experiment was laid out in uniformly sized plots measuring 12 m2 (4 m × 3 m) in Randomized Block Design containing six treatments and four replications. The treatment schedule comprised two sprayings, the first 15 days after t

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Sidhu, O. P., Vishal Kumar, and Hari M. Behl. "Variability in Neem (Azadirachta indica)with Respect to Azadirachtin Content." Journal of Agricultural and Food Chemistry 51, no. 4 (2003): 910–15. http://dx.doi.org/10.1021/jf025994m.

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Gangadhara, Parigi Ramesh Kumar, and Vishweshwaraiah Prakash. "Inhibition of rice bran lipase by azadirachtin from Azadirachta indica." Journal of the Science of Food and Agriculture 89, no. 10 (2009): 1642–47. http://dx.doi.org/10.1002/jsfa.3632.

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