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Relevant bibliographies by topics / Azepine derive

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Journal articles

Academic literature on the topic 'Azepine derive'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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Journal articles on the topic "Azepine derive"

1

Streef, J. W., H. C. van der Plas, N. Nieman, and C. H. Stam. "The reactivity of azepinyl anions, derived from 2-(diethylamino)-5-phenyl-3H-azepines, towards alkylating agents." Recueil des Travaux Chimiques des Pays-Bas 104, no. 6 (2010): 166–70. http://dx.doi.org/10.1002/recl.19851040603.

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2

Zhao, Wen-Bo, Shinpei Nakagawa, Atsushi Kato, et al. "General Synthesis of Sugar-Derived Azepane Nitrones: Precursors of Azepane Iminosugars." Journal of Organic Chemistry 78, no. 7 (2013): 3208–21. http://dx.doi.org/10.1021/jo400130p.

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3

Mikláš, R., N. Miklášová, M. Bukovský, and F. Devínsky. "Synthesis and antimicrobial properties of binaphthyl derived quaternary ammonium bromides." Acta Facultatis Pharmaceuticae Universitatis Comenianae 59, no. 1 (2012): 39–47. http://dx.doi.org/10.2478/v10219-012-0017-5.

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Synthesis and antimicrobial properties of binaphthyl derived quaternary ammonium bromides(S)-N-(2-(4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]azepin-1-yl)ethyl)-N, N-dimethyl-N-dodecyl ammonium bromide (S)-1a and (S)-N-(2-(4,5-dihydro-3H-dinaphtho[2,1-c:1',2'-e]azepin-1-yl)ethyl)-N, N-dimethyl-N-tetradecylammonium bromide (S)-1b have been synthesized as optically active quaternary ammonium salts starting from 1,1'-binaphthyl-2,2'-diol. Their antimicrobial activity expressed as minimal inhibition concentration (MIC) was tested against Gram-positive human pathogenic bacteria S. Aureus, Gram-negative

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4

Gregory, Brian, Eric Bullock, and Teng-Song Chen. "Intramolecular Michael-type additions. IV. Synthesis of 2-azabicyclo[3.2.1]oct-3-enes from 4-chloroalkyl-1,4-dihydropyridines." Canadian Journal of Chemistry 63, no. 4 (1985): 843–48. http://dx.doi.org/10.1139/v85-140.

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2-Azabicyclo[3.2.1]oct-3-enes, including examples having a spiro centre at C(8), may be obtained by the reaction of anions derived from 1,3-diketones or cyclopentadiene with 4-chloroalkyl-1,4-dihydropyridines or with azepines. Intermediate 4,5-dihydro-1H-azepines have been isolated under milder conditions. The structures of the bicyclic compounds were established using infrared, ultraviolet, nuclear magnetic resonance, and mass spectrometry. Pharmacological examination of selected compounds revealed low antimicrobial and hypotensive activity.

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5

Yu, Chu-Yi, and et al et al. "ChemInform Abstract: General Synthesis of Sugar-Derived Azepane Nitrones: Precursors of Azepane Iminosugars." ChemInform 44, no. 33 (2013): no. http://dx.doi.org/10.1002/chin.201333191.

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6

Pang, Yadong, Guoduan Liang, Fukai Xie, et al. "N-Fluorobenzenesulfonimide as a highly effective Ag(i)-catalyst attenuator for tryptamine-derived ynesulfonamide cycloisomerization." Organic & Biomolecular Chemistry 17, no. 8 (2019): 2247–57. http://dx.doi.org/10.1039/c9ob00059c.

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7

Ulfa, Siti Mariyah, Hideki Okamoto, and Kyosuke Satake. "Synthesis of 2-Methoxy-3H-Azepine Derived Compounds Through the Thermal Reaction between Alkylnitrobenzene and Tributylphosphine." Natural B 3, no. 1 (2015): 17–23. http://dx.doi.org/10.21776/ub.natural-b.2015.003.01.3.

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8

Macías, M. A., J. A. Henao, Lina María Acosta, and Alirio Palma. "Synthesis and X-ray powder diffraction data of 7-fluoro-2-exo-(2-methylpropen-1-yl)-2,3,4,5-tetrahydro-1,4-epoxybenzo[b]azepine." Powder Diffraction 28, no. 1 (2013): 49–52. http://dx.doi.org/10.1017/s0885715612000966.

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The stereoselective synthesis of 7-fluoro-2-exo-(2-methylpropen-1-yl)-2,3,4,5-tetrahydro-1,4-epoxybenzo[b]azepine was developed by intramolecular 1,3-dipolar cycloaddition of the nitrone derived from the corresponding 2-allyl-4-fluoro-N-(3-methylbut-2-enyl)aniline. The X-ray powder diffraction (XRPD) pattern for the new compound was analyzed and found to crystallize in a monoclinic system with space group P21/m (No. 11) and refined unit-cell parameters a = 11.655(5) Å, b = 5.850(2) Å, c = 18.314(4) Å, β = 104.27(3) and V = 1210.1 (6) Å3.

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9

Katritzky, Alan R., Stanislaw Rachwal, and Jing Wu. "A versatile method for the N, N-dialkylation of aromatic amines via Grignard reactions on N,N-bis(benzotriazolylmethyl)arylamines." Canadian Journal of Chemistry 68, no. 3 (1990): 456–63. http://dx.doi.org/10.1139/v90-069.

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Grignard reactions of N,N-bis(benzotriazolylmethyl)arylamines afford the corresponding N,N-dialkylarylamines in high yields. Electron-releasing substituents on the aryl ring facilitate the reaction. Arylamines are N,N-dialkylated with two different alkyl groups by a stepwise procedure: N-benzotriazolylmethylation of an amine followed by a Grignard reaction to introduce the first alkyl group, and repetition of the same procedure to introduce the second alkyl group. Grignard reagents derived from 1,4-dihalobutane, upon reaction with N,N-bis(benzotriazolylmethyl)arylamines, give the corresponding

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10

Patel, Rahul V., Bhupendra M. Mistry, Riyaz Syed, Nikhil M. Parekh, and Han-Seung Shin. "Pyrrolo[1,2-a]azepines Coupled with Benzothiazole and Fluorinated Aryl Thiourea Scaffolds as Promising Antioxidant and Anticancer Agents." Anti-Cancer Agents in Medicinal Chemistry 19, no. 15 (2019): 1855–62. http://dx.doi.org/10.2174/1871520619666190820151043.

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Background: Cancer remains a major health concern throughout history and is responsible for huge numbers of deaths globally. The sensitivity of cancer cells to anticancer drugs is a crucial factor for developing effective treatments. Methods: Pyrrolo[1,2-a]azepines coupled with benzothiazole and fluorinated aryl thiourea scaffolds have been synthesized, and their potential as cytotoxic agents was investigated against different cancer cell lines such as human ovarian cancer (SK-OV-3), cervical cancer (HeLa), colon adenocarcinoma (HT-29) and non-small-cell lung carcinoma (A549). Cytotoxicity of

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