Relevant bibliographies by topics / Azetidine-2-one

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Academic literature on the topic 'Azetidine-2-one'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Azetidine-2-one"

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Takagi, Hiroshi, Mika Shichiri, Miho Takemura, Miho Mohri та Shigeru Nakamori. "Saccharomyces cerevisiae Σ1278b Has Novel Genes of the N-Acetyltransferase Gene Superfamily Required for l-Proline Analogue Resistance". Journal of Bacteriology 182, № 15 (2000): 4249–56. http://dx.doi.org/10.1128/jb.182.15.4249-4256.2000.

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ABSTRACT We discovered on the chromosome of Saccharomyces cerevisiae Σ1278b novel genes involved in l-proline analogue l-azetidine-2-carboxylic acid resistance which are not present in the standard laboratory strains. The 5.4 kb-DNA fragment was cloned from the genomic library of thel-azetidine-2-carboxylic acid-resistant mutant derived from a cross between S. cerevisiae strains S288C and Σ1278b. The nucleotide sequence of a 4.5-kb segment exhibited no identity with the sequence in the genome project involving strain S288C. Deletion analysis indicated that one open reading frame encoding a pre
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2

Çelik, Ísmail, Mehmet Akkurt, Aliasghar Jarrahpour, Edris Ebrahimi, and Orhan Büyükgüngör. "4-(9-Anthryl)-1-phenylspiro[azetidine-3,9′-xanthen]-2-one." Acta Crystallographica Section E Structure Reports Online 65, no. 3 (2009): o501—o502. http://dx.doi.org/10.1107/s1600536809004255.

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3

Atioğlu, Zeliha, Mehmet Akkurt, Aliasghar Jarrahpour, Roghayeh Heiran, and Namık Özdemir. "1-(Morpholin-4-yl)-4-(2-nitrophenyl)spiro[azetidine-3,9′-xanthen]-2-one." Acta Crystallographica Section E Structure Reports Online 70, no. 7 (2014): o772—o773. http://dx.doi.org/10.1107/s1600536814013464.

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In the title compound, C22H21N3O5, the β-lactam (azetidin-2-one) ring is nearly planar [maximum deviation = 0.010 (1) Å] and makes dihedral angles of 69.22 (5), 55.32 (5) and 89.42 (4)° with the least-squares planes formed by the four C atoms of the morpholine ring, which adopts a chair conformation, the benzene ring and the xanthene ring system, respectively. In the crystal, C—H...O hydrogen-bond contacts connect neighbouring molecules into infinite zigzag chains running parallel to thebaxis.
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Abdullah, Shaima H., Bushra A. Khairallah, and Khalid A. Al-Badrany. "Preparation and characterization of some azetidine-2-one derivatives derived from benzothiazole-2-ol and evaluation of their biological activity." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 35, no. 01 (2025): 37. https://doi.org/10.59467/ijhc.2025.35.37.

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This study involves the use of hydrazones derived from 2-hydroxybenzothiazole as nucleophiles to prepare several heterocyclic azetidine derivatives by reacting the prepared hydrazone with chloroacetyl chloride. Dioxane was used as a solvent, and triethylamine was used as a catalyst. In addition to determining the melting point, the structures of the prepared compounds were confirmed by physical and spectroscopic methods, infrared, proton, and carbon nuclear magnetic resonance (1H and 13C-NMR) spectroscopy, and thin layer chromatography to track the reaction progress. The biological viability w
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Ahmed, Aya, and Monther Faisal. "In-silico molecular docking, ADME study, and molecular dynamic simulation of new azetidin-2-one derivatives with antiproliferative activity." Turkish Computational and Theoretical Chemistry 9, no. 1 (2024): 29–40. http://dx.doi.org/10.33435/tcandtc.1498365.

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Over the past two decades, protein kinase has been a heavily studied target in the development of new anti-proliferative medications. Heterocyclic systems have been identified as the preferred scaffold because of their wide range of biological properties. In this research, the objective was to design and develop fifteen novel azetidin-2-one derivatives and assess their cytotoxic potential as inhibitors of the epidermal growth factor receptor, which is considered one of the key factors influencing cell growth and proliferation. The crystal structure of inactive EGFR tyrosine kinase domain ligan
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6

Sandip, Sen, S. Easwari T., and De Biplab. "Antimicrobial and anti-nociceptive profile of some 4-(3-methyl-1-phenyl-1Hpyrazol-4-yl)-1-phenylazetidin-2-o." Journal of Indian Chemical Society Vol. 91, Nov 2014 (2014): 2089–99. https://doi.org/10.5281/zenodo.5741383.

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IIMT College of Medical Sciences, O. Pocket, Ganga Nagar, Meerut-250 001, Uttar Pradesh, India Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala-799 006, Tripura, India <em>E-mail </em>: biplab_32@yahoo.co.in <em>Manuscript received online 04 March 2014, revised 28 April 2014, accepted 16 June 2014</em> A new series of 4-(3-methyl-1-phenyl-1<em>H</em>-pyrazol-4-yl)-1-phenylazetidin-2-ones (7a-j) were prepared by intermolecular cyclization of Schiff bases (6a-j) and mono chloro acetyl chloride in the presence of base catalyst triethyl amine. The biological evalua
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Ramachandran, S., N. Vimeshya, K. Yogeshwaran, Binoy Varghese Cheriyan, and M. Vijey Aanandhi. "Molecular docking studies, synthesis, characterisation, and evaluation of azetidine-2-one derivative." RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY 14, no. 3 (2021): 1571–75. http://dx.doi.org/10.5958/0974-360x.2021.00277.8.

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8

Çelik, Ísmail, Mehmet Akkurt, Aliasghar Jarrahpour, Edris Ebrahimi, and Orhan Büyükgüngör. "4-(9-Anthryl)-1-(3-bromophenyl)spiro[azetidine-3,9′-xanthen]-2-one." Acta Crystallographica Section E Structure Reports Online 65, no. 10 (2009): o2522—o2523. http://dx.doi.org/10.1107/s1600536809037830.

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9

Baktır, Zeliha, Mehmet Akkurt, Aliasghar Jarrahpour, Edris Ebrahimi, and Orhan Büyükgüngör. "4-(9-Anthryl)-1-(2,4-dimethoxyphenyl)spiro[azetidine-3,9′-xanthen]-2-one." Acta Crystallographica Section E Structure Reports Online 65, no. 7 (2009): o1623—o1624. http://dx.doi.org/10.1107/s1600536809022739.

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10

Çelik, İsmail, Mehmet Akkurt, Aliasgar Jarrahpour, E. Ebrahimi, and Orhan Büyükgüngör. "Molecular structure of 4-(9-anthryl)-1-phenylspiro[azetidine-3,90-xanthen]-2-one." Acta Crystallographica Section A Foundations of Crystallography 65, a1 (2009): s234—s235. http://dx.doi.org/10.1107/s0108767309095166.

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Book chapters on the topic "Azetidine-2-one"

1

Taber, Douglass F. "The Carreira Synthesis of (±)-Gelsemoxonine." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0104.

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The traditional Chinese pharmacopeia includes Gelsemium elegans benth, from which the alkaloid gelsemoxonine 3 was isolated. Erick M. Carreira of the Eidgenössische Technische Hochschule Zürich envisioned (J. Am. Chem. Soc. 2013, 135, 8500) that the unusual azetidine ring of 3 could be established by Brandi contraction of 1 to give 2. Following Brandi and Salaün (Eur. J. Org. Chem. 1999, 2725), the hemiketal 4 was carried onto the aldehyde 9. Condensation with nitromethane followed by dehydration gave the unsaturated nitrile oxide, which cyclized to 10. Epoxidation of 10 across the more open f
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