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Journal articles on the topic 'Azote – Solubilité'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Babaei, Maryam, Elaheh Rahimpour, Esmaeil Mohammadian, and Abolghasem Jouyban. "Simulation of azole drugs’ solubility in mono and binary systems at different temperatures." Journal of Molecular Liquids 411 (October 2024): 125695. http://dx.doi.org/10.1016/j.molliq.2024.125695.

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2

Ghazouani, Hiba, Chokri Hafsi, Roua Amami, et al. "Evaluation of the effect of nitrogen nutrition on the water productivity of some varieties of durum wheat." JOURNAL OF OASIS AGRICULTURE AND SUSTAINABLE DEVELOPMENT 4, Special (2022): 200–206. http://dx.doi.org/10.56027/joasd.spiss262022.

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Durum wheat needs energy to accomplish the main metabolic and physiological functions; this energy is provided mainly by nitrogen which is also a fundamental constituent of the plant. Despite its importance and because of its high solubility, nitrogen is classified as a potential pollutant for the environment. The objective of this work is to study the response of four varieties of durum wheat (Karim, Razzak, INRAT100 and Dhahbi) to nitrogen treatment. The results showed that the new variety (Dhahbi) gave highest yield and water use efficiency either with or without fertilization thanks to the

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3

Rani, Nidhi, Praveen Kumar та Randhir Singh. "Molecular Modeling Studies of Halogenated Imidazoles against 14α- Demethylase from Candida Albicans for Treating Fungal Infections". Infectious Disorders - Drug Targets 20, № 2 (2020): 208–22. http://dx.doi.org/10.2174/1871526519666181130101054.

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Background:Imidazole is one of the most explored and marketed azole utilized for the treatment of fungal infections. Lanosterol 14α-demethylase (Cytochrome P450DM) is the active target site for azole antifungals.Aim and Objective:This study emphasized on evaluation of a series of halogenated imidazole analogues using molecular docking studies for anti-Candidal activity. Furthermore, the model was refined by molecular dynamic simulation.Methods:Halogenated imidazole analogues (PS1-PS30) were obtained from literature for the study. The imidazole analogues were prepared using Chem sketch and mole

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4

Kostina, M. V., L. G. Rigina, V. S. Kostina, A. E. Kudryashov, and R. S. Fedortsov. "Raschetnaya otsenka rastvorimosti azota i fazovogo sostava v stali na osnove Fe-13% Cr pri ee dopolnitel'nom legirovanii (Mn, Mo, V, Nb)." Микология и фитопатология, no. 2 (December 15, 2023): 64–77. http://dx.doi.org/10.31857/s086957332302009x.

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Estimates of the nitrogen solubility in model steels of various compositions based on Fe-13%Cr with additional alloying (a small amount from hundredths of a percent to 1.5%) with elements (Mn, Mo, V, Nb) that increase the solubility of nitrogen in iron-based solid solutions are calculated. 60 variants of compositions were studied. Based on previously obtained own experimental data for nitrogen-containing steels with a content of 16%Cr-5%Ni-Nb for martensitic steel, a preliminary assessment of the composition stability coefficient of nitrogen used in the calculations of its (nitrogen) solubilit

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5

Olagboye, S. A., and G. F. Hassan. "Synthesis, Characterization and Biocidal Evaluation of Azole-Based Ligandsmetal Complexes." International Journal of Applied Sciences and Biotechnology 1, no. 4 (2013): 258–65. http://dx.doi.org/10.3126/ijasbt.v1i4.9176.

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Different metal complexes of the azole-based ligands have been synthesized and characterized based on the solubility, percentage yield, melting points and conductivity a well as the antimicrobial evaluations on the selected fungi species of plant pathogens. The studies revealed that solid metal complexes were soluble in 80% water and 20% (DMSO) dimethylsulphuroxide and the percentage yields were of appreciable high while the conductivity results showed that metal complexes were non-electrolytes. The solid complexes were also screened against the fungi species: Rhizoctonia solani,Pythium aphain

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6

Ham, Young Yoon, James S. Lewis, and George R. Thompson. "Rezafungin: a novel antifungal for the treatment of invasive candidiasis." Future Microbiology 16, no. 1 (2021): 27–36. http://dx.doi.org/10.2217/fmb-2020-0217.

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Rezafungin is a novel echinocandin with exceptional stability and solubility and a uniquely long half-life allowing for front-loaded drug exposure with once-weekly dosing. Rezafungin has been shown comparable to other echinocandins, with activity against Candida spp. and Aspergillus spp. including subsets of echinocandin-resistant Candida auris and azole-resistant Aspergillus isolates. Available clinical data show robust safety and promising efficacy. Phase III trials will provide data on efficacy of rezafungin for the treatment of candidemia and invasive candidiasis and for the prevention of

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7

Akishina, E. A., and Е. А. Dikusar. "Chemical modification of different compounds with nitrogen-containing heterocycles." Proceedings of the National Academy of Sciences of Belarus, Chemical Series 57, no. 3 (2021): 356–84. http://dx.doi.org/10.29235/1561-8331-2021-57-3-356-384.

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Heterocyclic compounds have an extremely important practical application, since many heterocycles are the basis of the most valuable medicinal substances, both natural (vitamins, enzymes, alkaloids, etc.) and synthetic biologically active compounds. The work mainly considers the most relevant directions for various purposes drugs search by modifying known bioactive natural, organoelement and framework compounds with 1,2-azole, oxazole, oxadiazole, thiazole, triazole, pyridine, pyrimidine heterocycles over the past 10 years. Chemical modification makes it possible to increase the water solubili

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8

Nagpal, Manju, Nisha Raj, Gurjeet Singh Thakur, and Geeta Aggarwal. "Improved Solubility of Itraconazole Binary Dispersions using Neem Gum: Development and Characterization of Topical Gel." Current Bioactive Compounds 15, no. 4 (2019): 399–407. http://dx.doi.org/10.2174/1573407214666180926120619.

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Background: Itraconazole is a triazole derivative and possesses structural similarities to the azole group (imidazoles and triazoles). It is a broad spectrum fungistatic. It belongs to BCS class II category i.e. it has poor solubility and high permeability. Objective: Dissolution enhancement of poorly soluble itraconazole using purified neem gum as a natural carrier via binary dispersions and other methods was studied. Topical gel formulations of binary dispersions were developed and evaluated for in vitro and in vivo antifungal activity. Methods: Five batches of solid dispersions (SD1-SD5) in

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9

Jamiu, A. T., J. Albertyn, O. M. Sebolai, and C. H. Pohl. "Update on Candida krusei, a potential multidrug-resistant pathogen." Medical Mycology 59, no. 1 (2020): 14–30. http://dx.doi.org/10.1093/mmy/myaa031.

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Abstract Although Candida albicans remains the main cause of candidiasis, in recent years a significant number of infections has been attributed to non-albicans Candida (NAC) species, including Candida krusei. This epidemiological change can be partly explained by the increased resistance of NAC species to antifungal drugs. C. krusei is a diploid, dimorphic ascomycetous yeast that inhabits the mucosal membrane of healthy individuals. However, this yeast can cause life-threatening infections in immunocompromised patients, with hematologic malignancy patients and those using prolonged azole prop

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10

Mahajan, Karishma, Poonam Sharma, Minal Chauhan, and Vikrant Abbot. "Physicochemical analysis of bifonazole and cationic surfactant cetyl trimethyl ammonium bromide: Thermodynamic study in hydro-ethanolic solvent systems." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 35, no. 02 (2025): 401. https://doi.org/10.59467/ijhc.2025.35.401.

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Bifonazole (BF) is a multifaceted azole antifungal agent that efficiently targets a broad spectrum of fungi, including yeasts, molds, and dermatophytes. BF has been selected in this research work to enhance its transdermal permeability, as it belongs to the biopharmaceutics classification system class IV, which is characterized by low solubility and permeability. To begin, the thermodynamic properties of BF, lecithin, and the cationic surfactant cetyl trimethyl ammonium bromide were measured. The research involved evaluating different factors, including surface tension and density, to calculat

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11

Ren, Yun-Hao, Feng-Yuan Song, Jing-Yu Zhao, Bing-Wen Liang, and Li-Hua Peng. "Unlocking the Stratum Corneum Barrier to Skin Penetration for the Transdermal Delivery of Cyclovirobuxine D." Pharmaceutics 16, no. 12 (2024): 1600. https://doi.org/10.3390/pharmaceutics16121600.

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Background/Objectives: Cyclovirobuxine D, a natural compound derived from the medicinal plant Buxus sinica, demonstrates a diverse array of therapeutic benefits, encompassing anti-arrhythmic properties, blood pressure regulation, neuronal protection, and anti-ischemic activity. However, its limited solubility hinders the bioavailability of current oral and injectable formulations, causing considerable adverse reactions and toxicity. Methods: In this investigation, we embarked on an unprecedented exploration of the skin penetration potential of cyclovirobuxine D utilizing chemical penetration e

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12

Holubowitch, Nicolas. "Predicting Redox Potentials of Flow Battery-Relevant Model Electrolytes." ECS Meeting Abstracts MA2023-02, no. 4 (2023): 699. http://dx.doi.org/10.1149/ma2023-024699mtgabs.

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Redox flow batteries (RFBs) are rapidly gaining traction among large-scale storage solutions for intermittent renewable energy. Given the anticipated global scale of this technology, there is an intensive ongoing search for active electrolyte species containing all earth-abundant elements. Potential RFB actives must satisfy several criteria to maximize battery performance, namely, high solubility in the RFB solvent, optimum reduction potential, and chemical stability in all redox states. Given the near infinite possible molecular combinations of the primary atoms C, H, N, O, S, and Fe, computa

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13

Calvo, Natalia L., Sruthi Sreekumar, Laura A. Svetaz, María C. Lamas, Bruno M. Moerschbacher, and Darío Leonardi. "Design and Characterization of Chitosan Nanoformulations for the Delivery of Antifungal Agents." International Journal of Molecular Sciences 20, no. 15 (2019): 3686. http://dx.doi.org/10.3390/ijms20153686.

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Among different Candida species triggering vaginal candidiasis, Candida albicans is the most predominant yeast. It is commonly treated using azole drugs such as Tioconazole (TIO) and Econazole (ECO). However, their low water solubility may affect their therapeutic efficiency. Therefore, the aim of this research was to produce a novel chitosan nanocapsule based delivery system comprising of TIO or ECO and to study their suitability in vaginal application. These systems were characterized by their physicochemical properties, encapsulation efficiency, in vitro release, storage stability, cytotoxi

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14

Addetla, Sagarika* Boreda Sowmya Aprajitha Bhatnagar Dr. Kameswari. "FLUCONAZOLE: A REVIEW." Indo American Journal of Pharmaceutical Sciences (IAJPS) 03, no. 09 (2016): 1004–8. https://doi.org/10.5281/zenodo.154436.

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Fluconazole is a bis-triazole antifungal drug with novel pharmacokinetic properties (metabolic stability, relatively high water solubility) which contribute to its therapeutic activity. Fluconazole is a medication that is given either by mouth or intravenously. It is used to treat a variety of fungal infections, especially Candida infections of the vagina (yeast infections), mouth, throat, and bloodstream. This article describes about the uses of fluconazole drug in immunocompromised patients and in the treatment of other fungal infections. Fungal resistance to drugs in the azole class tends t

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15

Treinyte, Jolanta, Violeta Grazuleviciene, and Jolita Ostrauskaite. "Biodegradable Polymer Composites with Nitrogen- and Phosphorus-Containing Waste Materials as the Fillers/Biodegradowalne Kompozyty Polimerowe Wypełnione Odpadami Zawierającymi Azot I Fosfor." Ecological Chemistry and Engineering S 21, no. 3 (2014): 515–28. http://dx.doi.org/10.2478/eces-2014-0038.

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Abstract Composites consisting of polyvinyl alcohol, nitrogen- and phosphorus-containing waste materials were prepared and studied as materials for encapsulation of mineral fertilizers By-products of biodiesel production (rapeseed cake, crude glycerol), horn meal (waste product of haberdashery) and phosphogypsum (by-product of the production of phosphorus fertilizers) were used as the fillers of the composites. The films of the composites with the different amounts of nitrogen and phosphorus were prepared using different fillers or their mixtures. Mechanical, properties of the films, hygroscop

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16

Turner, W. W., and M. J. Rodriguez. "Recent Advances in the Medicinal Chemistry of Antifungal Agents." Current Pharmaceutical Design 2, no. 2 (1996): 209–24. http://dx.doi.org/10.2174/1381612802666220921175559.

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The need for new antifungal agents has never been greater. Over the last 10 years the incidence of life-threatening fungal infections has increased dramatically as the population of immunocompromised individuals induding cancer, organ transplant, and AIDS patients has increased. Present therapeutic options for· the treatment of these infections are limited to compounds in two classes, the polyenes and the azoles. Some polyene research still continues with analogs of amphotericin B in the hopes of decreasing toxicity. Much work continues in the azole area with follow-up compounds to fluconazole

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17

Waldron, Levi, Paul A. Cooper, and Tony Y. Ung. "Prediction of long-term leaching potential of preservative-treated wood by diffusion modeling." Holzforschung 59, no. 5 (2005): 581–88. http://dx.doi.org/10.1515/hf.2005.095.

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Abstract An approach to modeling leaching and leaching impacts of preservative components from treated wood is presented based on three simple laboratory determinations: the amount of preservative component available for leaching (Le), equilibrium dissociation of preservative into free water in wood (Di) and diffusion coefficients for component leaching in different wood directions (D). In this study, the following inorganic wood preservative systems were investigated: chromated copper arsenate (CCA), the copper component of copper azole (CA) and alkaline copper quaternary (ACQ), and boron in

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18

Mielnyk, T. V., and N. L. Kolycheva. "Study of the effect of bifonazole concentration on the antifungal activity of vaginal suppositories." Current issues in pharmacy and medicine: science and practice 17, no. 1 (2024): 48–51. http://dx.doi.org/10.14739/2409-2932.2024.1.294647.

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The analysis of the current state of pharmacotherapy for vulvovaginal candidiasis reveals that there is a contemporary need for the development of soft dosage forms for the local treatment of infectious diseases affecting the vulva and vagina. This should be based on azole derivatives that, despite possessing a well-established wide spectrum of antifungal and antibacterial effects, have not been utilized for vaginal administration in domestic formulations. The successful realization of this project would enable the field of domestic dermatology to provide effective, compliant, and affordable d

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19

Rani, Deepika, Vinit Kumar Sharma, and Ranjit Singh. "Voriconazole and Beauvercin Loaded Niosomal Mucoadhesive Nanogel as an effective Treatment for the Management of Oral Candidiasis." Research Journal of Pharmacy and Technology, June 25, 2024, 2549–55. http://dx.doi.org/10.52711/0974-360x.2024.00398.

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Oral candidiasis is a fungal infection, which affects the oral mucosa. The main causative agent of this is Candida albicans and as the literature indicates highest prevalence of Candida bloodstream infections in India. Most commonly azole derivatives such as miconazole, fluconazole, itraconazol etc. are used to manage the infection. However, their efficacy is compromised due to multidrug resistance. A new azole derivative voriconzole could be effective but its poor water solubility and bioavailability are seen as significant limitations. Its efficacy can be enhanced by combining it with beauve

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20

DEĞİRMENCİ, Levent, Özge KAYGUSUZ İZGÖRDÜ, and Cihan DARCAN. "Organik ve kimyasal gübre ile kullanılmak üzere mikroorganizma izolasyon ve karakterizasyonu." Biological Diversity and Conservation, December 27, 2023. http://dx.doi.org/10.46309/biodicon.2023.1226337.

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Isolation and Characterization of Microorganisms for Use with Manure and Chemical Fertilizers Levent Değirmenci1, Özge Kaygusuz İzgördü2, Cihan Darcan3 ORCID: 0000-0001-6608-0398; 0000-0002-3652-4266; 0000-0003-0205-3774 1 Corresponding author: Department of Chemical Engineering, Bilecik Şeyh Edebali University, 11210, Bilecik/Turkey Tel: +90 228 2141548, e-mail: levent.degirmenci@bilecik.edu.tr  2 Biotechnology Application and Research Center, Bilecik Şeyh Edebali University, 11210, Bilecik, Turkey 3 3Department of Molecular Biology and Genetics, Bilecik Şeyh Edebali U

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