Dissertations / Theses on the topic 'Bab'
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Lawson, Benjamin T. "The Qurʾan commentary of Sayyid ʻAlî Muḥammad, the Bab /." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72104.
Full textBab, Sebastian [Verfasser]. "Epsilon-mu-Logik - Eine Theorie propositionaler Logiken / Sebastian Bab." Aachen : Shaker, 2007. http://d-nb.info/1163609757/34.
Full textBiais, Pauline. "Synthèse de copolymères amphiphiles triblocs BAB par PISA-RAFT dans l'eau." Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS256.
Full textOver the past decade, the polymerization-induced self-assembly (PISA) has become an efficient tool for the preparation of block-copolymer nanoparticles at high solid contents, in both organic solvents and water. Nonetheless, most of the studied systems are currently based on simple AB diblock copolymers (where A = solvophilic, stabilizer block and B = solvophobic block). Another interesting class of block copolymers are associative BAB triblocks. To the best of our knowledge, very few studies report their synthesis by PISA and the polymerizations are performed in mixtures of alcohol and water. In this work, for the first time, a straightforward strategy to synthesize, in pure water, BAB triblock copolymers through the use of reversible deactivation radical polymerization is developed and studied in details. To this end, an hydrophilic, bifunctional macroRAFT agent of poly(N,N-dimethylacrylamide) with a central benzoic acid group was used in the aqueous dispersion polymerization of diacetone acrylamide. Various morphologies (spheres, fibers and vesicles) could be obtained with good polymerization controls. Moreover, we showed that the particle morphology and colloidal stability strongly depend on the degree of ionization of the central charge in the stabilizer loop. Then, the mechanism of formation of these triblock copolymers during PISA was investigated. Finally, we showed the possibility to form dynamic networks of BAB copolymers – using a one-pot process entirely in water – leading to the formation of thermoresponsive copolymer networks with tunable viscosity
Albanis, Elisabeth. "German-Jewish cultural identity from 1900 to the aftermath of the first world war : a comparative study of Moritz Goldstein, Julius Bab and Ernst Lissauer /." Tübingen : Niemeyer, 2002. http://catalogue.bnf.fr/ark:/12148/cb39055865n.
Full textKristen, Juliane Ute. "Amphiphilic BAB-triblock copolymers bearing fluorocarbon groups : synthesis and self-organization in aqueous media." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2012/6178/.
Full textIm Rahmen dieser Arbeit wurden neue fluorierte und unfluorierte mono- und bifunktionelle Trithiocarbonate der Typen Z-C(=S)-S-R und Z-C(=S)-S-R-S-C(=S)-Z zur Anwendung als CTAs (chain- transfer agents) im RAFT-Polymerisationsverfahren hergestellt. Alle CTAs wurden erfolgreich auf ihre Effizienz zur Steuerung des radikalischen Polymerisationsverfahrens hin durch Polymerisation von Styrol (M3) getestet. Neben GPC-Messungen wurden Endgruppenanalysen der synthetisierten Blockcopolymere mittels 1H-, 19F-NMR und in manchen Fällen auch UV-Vis Spektroskopie durchgeführt. Dazu wurden die Z- und/oder R-Gruppen der CTAs mit geeigneten fluorierten Gruppen versehen. Durch Anwendung des RAFT Verfahrens konnten symmetrische Triblockcopolymere vom Typ BAB bzw. mit einer Fluoralkylgruppe endgecappte unsymmetrische Polymere in nur zwei bzw. einem Polymerisationsschritt hergestellt werden. Das RAFT- Polymerisationsverfahren ermöglicht sowohl die Polymerisation hydrophiler Monomere wie N-Isopropylacrylamid (NIPAM) (M1) oder N-Acryloylpyrrolidin (NAP) (M2) für die A-Blöcke als auch der hydropoben Monomere Styrol (M3), 2-Fluorostyrol (M4), 3-Fluorostyrol (M5), 4- Fluorostyrol (M6) und 2,3,4,5,6- Pentafluorostyrol (M7) für die B-Blöcke. Die Eigenschaften der Blockcopolymere in verdünnten, konzentrierten und hochkonzentrierten wässrigen Lösungen wurden mittels DLS, Trübungsphotometrie, 1H- und 19F-NMR, Rheologie, CMC- sowie Schaumhöhen- und Oberflächenspannungsmessungen und Lichtmikroskopie untersucht. Weiterhin wurden ihre Eigenschaften als Emulgatoren und in Mikroemulsion untersucht. Das Micellbildungsverhalten der hydrophob endfunktionalisierten Polymere wurde mittels DLS Messungen in verdünnter organischer Lösung untersucht. Alle untersuchten BAB-Triblöcke bildeten Micellen und zeigten Oberflächenaktivität bei Raumtemperatur in verdünnter, wässriger Lösung. Weiterhin zeigen die wässrigen Lösungen der Polymere mäßige Schaumbildung. Mit verschiedenen Öltypen und Ölkonzentrationen wurden Emulsionen bzw. Mikroemulsionen gebildet. In Mikroemulsion wurde durch Zugabe von BAB-Triblockopolymeren kein Boosting-Effekt erzielt werden. Bei Untersuchung höherer Polymerkonzentrationen wurde die Bildung von Hydrogelen mittels rheologischer Messungen nachgewiesen. Verschiedene Substrate konnten benetzt werden. Die hydrophob endgecappten Polymere bilden in verdünnter organischer Lösung Micellen, die mittels DLS untersucht wurden, und zeigen somit Tensidverhalten in nichtwässriger Lösung.
Ullinger, Jaime. "Skeletal Health Changes and Increasing Sedentism at Early Bronze Age Bab edh-Dhra’, Jordan." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275258919.
Full textNassif, H. "Home under siege : Bab al-Hara, televising morality and everyday life in the Levant." Thesis, University of Westminster, 2015. https://westminsterresearch.westminster.ac.uk/item/9yxq0/home-under-siege-bab-al-hara-televising-morality-and-everyday-life-in-the-levant.
Full textMassucato, Jaqueline Cristina. "Professora, educadora ou bab?? desafios para a reconstru??o da identidade profissional na educa??o infantil." Pontif?cia Universidade Cat?lica de Campinas, 2012. http://tede.bibliotecadigital.puc-campinas.edu.br:8080/jspui/handle/tede/694.
Full textThis study focuses on teacher s training in early childhood education, whose search problem lies in knowing the role of initial training in the reconstruction process of these professional identities, investigating the function of this training in the reconstruction of social representations of children education s future teachers about their profession. We developed a study based on qualitative research approach, whose theoretical and methodological framework was based on the Theory of Social Representations of Moscovici (2009). The data collection technique adopted was the application of questionnaires to 57 new students and 46 graduates of Pedagogy course of a private university in S?o Paulo state, among which we selected five graduating students to participate in semistructured interviews. The collected data were analyzed based on the identification of the following categories: teacher identity, conception of teacher and teacher training s challenges. The results indicated that this training course seems to have provided recognition to the early childhood s teacher as a professional one, with specific knowledge for its actions and, therefore, who needs to be professionally and socially recognized by the importance of its function. The investigation underscored how important is to rethink childhood s teacher identity in terms of professional recognition and its social, political and professional role. We value the contributions of this training course to the review of concepts and representations that interfere with this identity reconstruction and we realize that challenges are made to improve initial training in this course, such as internship, which needs to articulate the theory and promote more critical thoughts about the foundational concepts of the area; the need for deeper analysis of the curriculum to enable review of conceptions, allowing redraftings that deconstruct socially crystallized representations. Finally, by placing emphasis on these issues, we believe we are contributing to Educational research and, more specifically, to the identity formation of Childhood s Teachers, who belongs to a professional group entitled to exercise its teacher profession and the social function that historically characterizes it.
Este estudo aborda a forma??o de professores de educa??o infantil, cujo problema de pesquisa situa-se em conhecer o papel da forma??o inicial no processo de reconstru??o de sua identidade profissional, objetivando investigar o papel dessa forma??o na reconstru??o das representa??es sociais de futuras professoras de educa??o infantil sobre a profiss?o. Desenvolvemos um estudo baseado na abordagem qualitativa de pesquisa, cujo referencial te?rico-metodol?gico pautou-se na Teoria das Representa??es Sociais de Moscovici (2009). As t?cnicas de coleta de dados adotadas foram a aplica??o de 57 question?rios a alunos ingressantes e 46 concluintes de um curso de pedagogia de uma universidade particular do Estado de S?o Paulo, dentre os quais selecionamos cinco alunas concluintes para participarem da realiza??o de entrevistas semi-estruturadas. Os dados coletados foram analisados a partir da identifica??o das seguintes categorias de an?lise: identidade docente, concep??o de professor e desafios para a forma??o docente. Os resultados obtidos indicaram que esse curso de forma??o parece ter proporcionado o reconhecimento do professor da educa??o infantil enquanto pertencente ? categoria profissional professor, com saberes espec?ficos para sua atua??o e que, portanto, necessita ser reconhecido profissional e socialmente pela import?ncia de sua fun??o. A investiga??o ressaltou a necessidade de se repensar a identidade desse professor em termos de reconhecimento da profiss?o docente e do seu papel social, pol?tico e profissional. Destacamos as contribui??es desse curso de forma??o no que se refere ? revis?o de conceitos e representa??es que interferem nessa reconstru??o identit?ria e pudemos perceber que desafios est?o postos para aperfei?oar a forma??o inicial nesse curso, como a quest?o dos est?gios, que precisam articular a teoria e promover reflex?es mais cr?ticas sobre as concep??es fundantes da ?rea; a necessidade de uma an?lise mais aprofundada do curr?culo, a fim de permitir revis?es das concep??es, possibilitando reelabora??es que desconstruam representa??es cristalizadas socialmente. Finalmente, ao colocar essas quest?es em relevo, acreditamos estar contribuindo com a pesquisa em Educa??o e mais especificamente com a forma??o identit?ria dos professores de Educa??o Infantil, pertencentes a um grupo profissional que tem direito de exercer sua profissionalidade docente e a fun??o social que o define historicamente enquanto tal.
CHACUKI, AZZEDDINE. "Les mouvements de terrain et les risques associes dans la region de bab-taza (rif occidental)." Université Louis Pasteur (Strasbourg) (1971-2008), 1991. http://www.theses.fr/1991STR10003.
Full textThe studied zone is located on the calcareous-front-dorsal at east of the village bab-taza. The zone is cutted by the calcareous, sandstones and marls formation. This zone has serious problems due to earth movement. Which come from release factor and site-orogenic raising, rain, human density, geology (mineralogy, granulometric, structurs, and so on) morphology (slope, horizontal concavity)-, are differents according to the area, they are only translational or rotational at mountain scale, but in the basins and in the partitions rotational movements and also mudflow take place
Baanannou, Aissette. "Étude de la régulation transcriptionnelle des gènes bab au cours du développement des appendices chez la drosophile." Toulouse 3, 2012. http://thesesups.ups-tlse.fr/1838/.
Full textA proper spatio-temporal expression of bric-a-brab2 is required for the proximo-distal (PD) patterning of the Drosophila leg and antenna. Here, we deciphered the molecular mechanisms controlling bab2 expression in developing distal leg (4 rings) and antennal (2 rings) tissues. Using site-targeted GFP reporter assay and BAC recombineering, we show that restricted bab2 expression relies on a single 0. 56 kb cis-regulatory module (CRM), which is necessary and sufficient to drive normal Bab2 function in both developing leg and antenna. Through deletion and site-directed mutagenesis approaches, we identified discrete DNA motifs acting either positively or negatively. Finally, loss- and gain-of-function genetic analyses in combination with in-vitro electrophoretic mobility shift assays established that the Distal-less homeodomain protein directly activates bab2 in all rings, whereas the Rotund C2H2 zinc-finger protein is specifically required for direct activation in the most proximal rings. This work paves the way to decipher at the molecular level how to make concentric rings from an epithelial layer in order to organize the PD limb patterning
Johnson, Philip Alan 1958. ""The Refutation of the Grammarians" by Ibn Mada' al-Qurtubi: A translation, with syntactic analysis of "Bab al-Ishtighal"." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/282645.
Full textNEY, PASCAL Fontana Marc. "ETUDE DE L'ORIGINE DES PROPRIETES ELECTROOPTIQUES ET OPTIQUES NON LINEAIRES DU METABORATE DE BARYUM (-BAB#2O#4) PAR SPECTROSCOPIE RAMAN /." [S.l.] : [s.n.], 1998. ftp://ftp.scd.univ-metz.fr/pub/Theses/1998/Ney.Pascal.SMZ9864.pdf.
Full textNascimento, Adriane Geralda Alves do. "Um estudo sobre o comportamento de comunicação boca a boca no setor de serviços." Universidade do Vale do Rio do Sinos, 2010. http://www.repositorio.jesuita.org.br/handle/UNISINOS/2748.
Full textNenhuma
A comunicação boca a boca (BAB) tem sido considerada elemento fundamental em marketing. A justificativa para a escolha do tema reside na relevância que essa comunicação não controlada tem recebido no contexto de marketing de relacionamento, como uma forma não geradora de custos para empresa e uma fonte de informações considerada mais segura para os clientes. Muitas pesquisas apontam diferenças significativas entre resultados do comportamento BAB que indicam que estudos específicos devem ser ampliados. Assim, esta pesquisa aplica o modelo de Brown et al. (2005) considerando a investigação dos elementos que impactam no comportamento BAB sob a perspectiva do consumidor em um novo contexto. Esse modelo foi testado por meio de uma pesquisa descritiva, baseada em uma survey com 330 consumidores de um hotel da região da grande Goiânia. Como resultado da pesquisa foi possível validar o modelo utilizando a técnica de Modelagem de Equações Estruturais e avaliar o impacto da satisfação no comportamento de BAB, identific
The word-of-mouth communications (WOM) has been considered a fundamental marketing element. The reason for this theme’s choice is the relevance that this uncontrolled communication has gained at the relationship marketing context, as costs free for companies and considered more reliable for costumers. Many researches point those relevant differences between behavior results of WOM showing that specific studies shall be amplified. So, this research applies the model of Brown et al. (2005) considering the investigation of the elements that impact on the WOM behavior under costumer’s perspective in a new context. That model was tested through a descriptive survey applied to 330 customers of a hotel in Goiânia. As result of the research we could validate both models using the Structural Equations Modelling technique and evaluate the satisfaction impact on the behavior of WOM, identifying if this satisfaction has a positive influence on WOM, also if the commitment and trust can be considered a positive mediator o
Schöniger, Martin. "Die Schlüsselrolle des Helicobacter-pylori-Adhärenz-Faktors "Blutgruppen-Antigen-bindendes-Adhäsin" (Bab A) bei der Entstehung schwerwiegender histologischer Veränderungen der menschlichen Magenschleimhaut." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969379706.
Full textKristen, Juliane Ute [Verfasser], and Andre [Akademischer Betreuer] Laschewsky. "Amphiphilic BAB-triblock copolymers bearing fluorocarbon groups : synthesis and self-organization in aqueous media [[Elektronische Ressource]] / Juliane Ute Kristen. Betreuer: André Laschewsky." Potsdam : Universitätsbibliothek der Universität Potsdam, 2012. http://d-nb.info/1026808405/34.
Full textWürth, Anna. "As-Sari'a fi Bab al-Yaman Recht, Richter und Rechtspraxis an der familienrechtlichen Kammer des Gerichts Süd-Sanaa (Republik Jemen) 1983-1995 /." Berlin : Duncker & Humblot, 2000. http://catalog.hathitrust.org/api/volumes/oclc/46800420.html.
Full textPerry, V. J. "An analysis of enamel hypoplasia and other dental conditions in an Early Bronze Age IA population from Bab edh-Dhra', Southern Jordan." Thesis, London School of Economics and Political Science (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494735.
Full textChau, Irene. "An empirical comparison using both the term structure of interest rates and alternative models in pricing options on 90-day BAB futures." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 1999. https://ro.ecu.edu.au/theses/1207.
Full textLours, Corinne. "Contrôle de l'identité cellulaire par les régulateurs transcriptionnels à domaine BTB/POZ Bric à brac 1 et Bric à brac 2 chez Drosophila melanogaster." Clermont-Ferrand 1, 2003. http://www.theses.fr/2003CLF1MM07.
Full textSilva, de Castro Sandra. "Contrôle génétique de l'établissement et de la plasticité de la pigmentation abdominale chez Drosophila melanogaster." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS320/document.
Full textPhenotypic plasticity is the ability of a given genotype to produce different phenotypes in response to different environmental factors such as temperature, nutrition or presence of predators. This phenomenon allows the adaptation of individuals to their fluctuating environments. It can also facilitate evolution, as it broadens the range of phenotypes produced by a given genotype. As a model of phenotypic plasticity, we study the abdominal pigmentation in Drosophila melanogaster females. Indeed, this trait is temperature-sensitive: drosophila females are darker when they develop at lower temperatures particularly in the posterior segments. In the laboratory, it has been previously shown, that tan (t), a gene encoding a pigmentation enzyme, is more expressed at 18°C than at 29°C. Moreover, this gene plays an essential role in the phenotypic plasticity of abdominal pigmentation in Drosophila melanogaster females. During my thesis, I aimed to characterize the gene regulatory network involved in t regulation in the abdominal epidermis of Drosophila melanogaster females. I also tried to identify, in this network, the actors mediating the effect of temperature on t expression. Using a candidate gene approach, I showed that the transcription factors Bric-à-brac (Bab) and Abdominal-B (Abd-B) are involved in the phenotypic plasticity of abdominal pigmentation by regulating t. Furthermore, I performed a genetic screen targeting 573 genes encoding transcription factors and chromatin regulators to identify new regulators of t. At the end of this screen, I obtained a list of 27 genes involved in this regulation. I then started the functional characterization of two of these candidates: forkhead box subgroup O (foxo) encoding a transcription factor involved in the insulin response pathway and little imaginal discs (lid) encoding a histone demethylase
Neves, Person Pereira. "Síntese e caracterização de filmes finos da fase beta-BaB2O4." Universidade de São Paulo, 2001. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-11112013-173915/.
Full textThe main objective of this work was to prepare and characterize \'BETA\'-Ba\'B IND.2\'\'O IND.4\' (BBO) thin films. Thin and thick films were prepared using two different techniques, the polymeric precursor method (Pechini method) and the electron beam evaporation technique. In the samples obtained by the polymeric method, the BaO/\'B IND.2\'\'O IND.3\' ratio played an important role in the stabilization of the BBO phase. Stabilization, in this case, was only attained when the sample was prepared using a very high percentage of boron, i.e., a ratio of 70%\'B IND.2\'\'O IND.3\' and 30%BaO (weight percent). This composition is far from the stoichiometric one normally used to prepare the Ba\'B IND.2\'\'O IND.4\' compound. A chemical analysis of this sample revealed that there was a loss of boron during synthesis by evaporation. Due to the low viscosity of this solution, the films obtained by dip coating were very thin, making X-ray and microstructural analyses very difficult. The Pechini method was modified by replacing ethylene glycol with sorbitol, which stabilized the BBO phase in a stoichiometric composition. The solution obtained from this sample was transparent and stable, and thin films obtained from this solution presented a thickness of approximately 160 nm after only one deposition. For the films obtained by electron beam evaporation, different evaporation sources were used to produce the BBO phase. Heating the substrate in-situ was inefficient to obtain crystalline thin films, even when heated at 700°C. X-ray diffraction measurements showed that it was possible to produce the BBO phase when the sample was heated ex-situ at 650°C. The surface roughness and microstructure of the thin films was found to depend on the source of evaporation, the type of substrate and the ex-situ temperature to which the film was subjected. A comparison of the films obtained by the polymeric precursor method and those obtained by electron beam evaporation revealed that using the latter the films thickness can be varied from 0.4 to 1.7m
Sherzad, Abdul Rahman [Verfasser], Uwe [Akademischer Betreuer] Nestmann, Uwe [Gutachter] Nestmann, Niels [Gutachter] Pinkwart, Sebastian [Gutachter] Bab, and Nazir [Gutachter] Peroz. "Shaping the selection of fields of study in Afghanistan through educational data mining approaches / Abdul Rahman Sherzad ; Gutachter: Uwe Nestmann, Niels Pinkwart, Sebastian Bab, Nazir Peroz ; Betreuer: Uwe Nestmann." Berlin : Technische Universität Berlin, 2018. http://d-nb.info/1164076450/34.
Full textWolf, Aaron B. "Determining Whether Spectrophotometer CIE L*a*b* Color Analysis is an Effective Alternative to Munsell Soil Color Charts for the Study of Burnt Bones: Insights From Analysis of Bab edh-Dhra EB II-III Burnt Bones." Oberlin College Honors Theses / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=oberlin1305140303.
Full textSilva, de Castro Sandra. "Contrôle génétique de l'établissement et de la plasticité de la pigmentation abdominale chez Drosophila melanogaster." Electronic Thesis or Diss., Sorbonne université, 2018. http://www.theses.fr/2018SORUS320.
Full textPhenotypic plasticity is the ability of a given genotype to produce different phenotypes in response to different environmental factors such as temperature, nutrition or presence of predators. This phenomenon allows the adaptation of individuals to their fluctuating environments. It can also facilitate evolution, as it broadens the range of phenotypes produced by a given genotype. As a model of phenotypic plasticity, we study the abdominal pigmentation in Drosophila melanogaster females. Indeed, this trait is temperature-sensitive: drosophila females are darker when they develop at lower temperatures particularly in the posterior segments. In the laboratory, it has been previously shown, that tan (t), a gene encoding a pigmentation enzyme, is more expressed at 18°C than at 29°C. Moreover, this gene plays an essential role in the phenotypic plasticity of abdominal pigmentation in Drosophila melanogaster females. During my thesis, I aimed to characterize the gene regulatory network involved in t regulation in the abdominal epidermis of Drosophila melanogaster females. I also tried to identify, in this network, the actors mediating the effect of temperature on t expression. Using a candidate gene approach, I showed that the transcription factors Bric-à-brac (Bab) and Abdominal-B (Abd-B) are involved in the phenotypic plasticity of abdominal pigmentation by regulating t. Furthermore, I performed a genetic screen targeting 573 genes encoding transcription factors and chromatin regulators to identify new regulators of t. At the end of this screen, I obtained a list of 27 genes involved in this regulation. I then started the functional characterization of two of these candidates: forkhead box subgroup O (foxo) encoding a transcription factor involved in the insulin response pathway and little imaginal discs (lid) encoding a histone demethylase
Dalzell, Jessica L. "Beyond the Bag Ban: Voluntary Strategies for Reducing Disposable Bag Use in Athens, Ohio." Ohio University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1556868382159416.
Full textDalwai, Sameena. "Performing caste : the ban on bar dancing in Mumbai." Thesis, Keele University, 2012. http://eprints.keele.ac.uk/3813/.
Full textTrialonis, Christie Chryssoula. "A study to determine the effects of utilizing first language books on second language reading through the use of the Borrow-a-Book (BAB) program supported by monthly Parent Read Aloud Training (PRAT) workshops." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0022/MQ50376.pdf.
Full textBarrezueta, Luis Fernando Mesias [UNIFESP]. "Imuno-expressão das proteínas da família BCL-2 (BCL-2. BCL-XL, BAX, BAK, BAD) em câncer gátrico, preparados em arranjo em matriz (TMA)." Universidade Federal de São Paulo (UNIFESP), 2009. http://repositorio.unifesp.br/handle/11600/9724.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Em casos de carcinoma gástrico, para contribuir ao conhecimento do processo de carcinogênese: Objetivo: Estudar a expressão das proteínas da família Bcl-2 (BcI-2, Bcl-xl, Bak, Bad, Bax). Correlacionar a expressão destas proteínas com 0 índice apoptótico mediante a expressão da proteína Caspase 3 clivada, com 0 índice mit6tico mediante a expressão da proteína Ki-67 e com a expressão da proteína p53. Método: Técnica de arranjo em matriz de amostras teciduais (TMA): em 87 amostras de adenocarcinomas gástricos (grupo teste) e de mucosa gástrica não tumoral (grupo controle) foi avaliada a imuno-expressão das proteínas da família BcI-2 (BeI-2, Bcl-xl, Bak, Bad, Bax), da proteína p53, da proteína caspase 3 e da proteína Ki-67. Resultados: Todas as proteínas examinadas foram observadas nos adenocarcinomas e mucosa não tumoral, porem com diferenças de expressão em relação à porcentagem de positividade e intensidade. Observamos: i) Houve associação entre 0 tamanho do tumor e a proteína p53. ii) Houve associação da proteína Bad no adenocarcinoma com a idade dos pacientes. iii) Associação das proteínas Bax, Bad e Ki-67 com 0 adenocarcinoma de tipo intestinal. iv) As proteínas Bcl-xl, Bak, Bad, p53 e Ki-67 apresentaram diferenças estatisticamente significantes entre a imuno-expressão no tumor e na mucosa não tumoral. v) Associação das proteínas Bax, Bak e Bad na mucosa não tumoral. vi) Não houve correlação da imunoexpressão das proteínas com a sobrevida dos pacientes. Conclusão: A expressão aumentada da proteína Bcl-xl nos adenocarcinomas, com evidente diferença de expressão entre 0 grupo teste e 0 grupo controle, esta relacionada com 0 efeito anti-apoptótico da proteína. A expressão reduzida das proteínas Bak e Bad e a expressão aumentada das proteínas p53 e Ki-67 nos adenocarcinomas demonstram 0 desequilíbrio entre morte e proliferação celular, permitindo 0 crescimento descontrolado das células neoplásicas.
Purpose: To study the immunoexpression of Bcl-2 family proteins (Bcl-2, Bcl-xl, Bax, Bak, Bad) and to evaluate the correlation between the immunoexpression of these proteins with the cleaved caspases 3, Ki-67 and p53 immuno-expression. Methods: A TMA paraffin block was constructed with gastric carcinoma tissue (test group) and normal gastric adjoining mucosa (control group) of 87 patients. The TMA block was submitted to immunohistochemistry for Bcl-2, Bcl-xl, Bax, Bak, Bad, p53 and-cleaved Caspase 3. Results: All studied proteins were present in tumor and normal gastric adjoining mucosa, but with different intensity and amount of positive cells. i) There was an association between tumor size and p53 expression. ii) association between Bad expression in the tumor and patient’s age. iii) Intestinal type adenocarcinoma was positively correlated with the expression of Bax, Bad and Ki-67. iv) The protein Bcl-xl, Bak, Bad, p53 and Ki-67 showed statistically significant differences between the immuno-expression in tumor and normal gastric adjoining mucosa. v) There was an association between the proteins Bax, Bak and Bad expression in the normal gastric adjoining mucosa. vi) No correlation between patient’s survival rates and the expression of the proteins was observed. Conclusions: The higher expression of Bcl-xl protein in adenocarcinoma, the difference of Bcl-xl expression between test group and control group, might be related with the anti-apoptotic effect of this protein. The lower expression of Bak and Bad and the increased expression of p53 protein and Ki-67 protein in adenocarcinomas demonstrate the imbalance between death and cellular proliferation, which allows the uncontrolled tumor cell proliferation.
FAPESP: 04/09932-4
FAPESP: 06/54187-0
TEDE
Karch, Jason. "The Role of Bax and Bak in Necrotic Cell Death." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353099747.
Full textHachimi, Alaoui Abdallah el. "Contribution à l'analyse des spectres de BaH et BaD par spectrométrie de Fourier de la fluorescence induite par laser étude des états ... de BaH et BaD, étude du complexe ... de BaH /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37617801t.
Full textLeshchiner, Elizaveta S. "Dissecting the Mechanisms of Direct Activation for Proapoptotic BAK and BAX." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10778.
Full textDanielsson, Michaela. "The Plastic Bag Ban in Rwanda: Local Procedures and Successful Outcomes." Thesis, Uppsala universitet, Statsvetenskapliga institutionen, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-313576.
Full textHachimi, Alaoui Abdallah el. "Contribution à l'analyse des spectres de BaH et BaD par spectrométrie de Fourier de la fluorescence induite par laser : étude des états H2Δ de BaH et BaD, étude du complexe H2Δ -A2π -b2Σ de BaH." Nice, 1987. http://www.theses.fr/1987NICE4103.
Full textWhite, Sarah. "Pro-apoptotic bax and bak control beta-cell death and early endoplasmic reticulum stress signalling." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44609.
Full textMignard, Vincent. "Rôle des sphingolipides et des MAM dans l'activité des protéines pro-apoptotiques Bax et Bak." Nantes, 2015. https://archive.bu.univ-nantes.fr/pollux/show/show?id=f5341358-f156-44f7-b830-9aa90095f905.
Full textThe study of apoptosis is important to develop new anti-cancer strategies. The mitochondrial apoptotic pathway is tightly regulated by the interaction network of the Bcl-2 family proteins but other molecular actors are involved in the régulation of apoptosis, in particular, a family of bioactive lipids : sphingolipids. The recent studies have shown that the interactions between endoplasmic reticulum (ER) and mitochondria (via a specific region of the ER called Mitochondria associated membrane, MAM) are also involved in the regulation of apoptosis. We have developed a subcellular fractionation protocol for the isolation of mitochondria fraction, purified mitochondria and MAM. The proteic and lipidic compositions of these fractions were analyzed by WB and HPLC-MS. We compared the compositions of subcellular fractions at normal and apoptotic conditions. Our results show that induction of apoptosis causes the redistribution of the Bcl-2 family proteins including Bax transduction to mitochondria and MAM and an important increase of Bcl-2 expression at MAM Regarding lipid profiles, inductions of apoptosis increases ceramide level at mitochondria and decreases sphyngomyelin in the MAM fraction. Taken together, these results may suggest that the MAM could play an important role in the subcellular localization of Bcl-2 family proteins during apoptosis, potentially through synthesis and/or trafficking of sphingolipids
Schulte, Sven [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Ausbildungsreife: Bewertung eines Konstruktes : Die Indikatoren der Bundesagentur für Arbeit im mehrperspektivischen Vergleich / Sven Schulte." Bielefeld : wbv Media, 2018. http://wbv.de/bai.
Full textKost, Jakob [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Erreichte und verpasste Anschlüsse - Zur Durchlässigkeit der Schweizer Sekundarstufe II / Jakob Kost." Bielefeld : wbv Media, 2018. http://wbv.de/bai.
Full textKarges, Torben [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Wissensmanagement und Kommunikationsprozesse im Kfz-Service : Bedeutung und Perspektiven für die Facharbeit in Kfz-Werkstätten / Torben Karges." Bielefeld : W. Bertelsmann Verlag, 2017. http://wbv.de/bai.
Full textBremer, Anne [Verfasser]. "Diffusion des Internet der Dinge auf die mittlere Beschäftigungsebene der Industrie / Anne Bremer." Bielefeld : W. Bertelsmann Verlag, 2017. http://wbv.de/bai.
Full textLange, Silke [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, Georg [Herausgeber] Spöttl, and Susan [Herausgeber] Seeber. "Die Berufsausbildungseingangsphase : Anforderungen an Azubis und ihre Bewältigungs strategien am Bsp. des Kfz-Mechatronikerhandwerks / Silke Lange." Bielefeld : wbv Media, 2019. http://www.wbv.de/bai.
Full textGrüll, Sylke [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Die Berufseingangsphase im Lehramt an berufsbildenden Schulen : Herausforderungen, Handlungsmuster und Empfehlungen / Sylke Grüll." Bielefeld : wbv Media, 2019. http://www.wbv.de/bai.
Full textSchütt-Sayed, Sören [Verfasser], Marianne [Herausgeber] Friese, Klaus [Herausgeber] Jenewein, Susan [Herausgeber] Seeber, and Georg [Herausgeber] Spöttl. "Nachhaltigkeit im Unterricht berufsbildender Schulen : Analyse, Modellierung und Evaluation eines Fort- und Weiterbildungskonzepts für Lehrkräfte / Sören Schütt-Sayed." Bielefeld : wbv Media, 2020. http://www.wbv.de/bai.
Full textKönig, Maria [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Gesprächskompetenzen Auszubildender fördern : Konzeption und Wirkung eines Lernarrangements in einer gewerblich-technischen Berufsausbildung / Maria König." Bielefeld : wbv Media, 2019. https://www.wbv.de/bai.
Full textHesse, Rüdiger [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Bachelor und dann? : Aspirationen, Entscheidungen und Bildungsübergänge von Studierenden unterschiedlicher Herkunft / Rüdiger Hesse." Bielefeld : wbv Media, 2018. http://www.wbv.de/bai.
Full textWeber-Frieg, Sabine [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "Selbstreflexives, transformatives Lernen in der Altenpflegeausbildung : Wege zum professionellen Handeln / Sabine Weber-Frieg." Bielefeld : wbv Media, 2018. http://wbv.de/bai.
Full textLiebig, Manuela [Verfasser], Marianne [Herausgeber] Friese, Klaus [Herausgeber] Jenewein, Susan [Herausgeber] Seeber, and Georg [Herausgeber] Spöttl. "Arbeitsaufgabenbezug in der beruflichen Didaktik der Sozialpädagogik : Neue Ansätze für das Lehren und Lernen / Manuela Liebig." Bielefeld : wbv Media, 2020. http://www.wbv.de/bai.
Full textKleinhans, Janne [Verfasser], Klaus [Herausgeber] Jenewein, Marianne [Herausgeber] Friese, and Georg [Herausgeber] Spöttl. "IT-gestützte Werkzeuge zur Kompetenzmessung : Ausgewählte Ansätze vom adaptiven Test bis zum Unternehmensplanspiel / Janne Kleinhans." Bielefeld : wbv Media, 2018. http://www.wbv.de/bai.
Full textGao, Yuan. "Conversion of BaF₂ to BaO for in-situ growth of Y-Ba-Cu-O thin films." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28987.
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Physics and Astronomy, Department of
Graduate
Howells, Christopher Corey. "The Modeling and Analysis of the Apoptotic BAD/tBID/BAK Pathway as a Chemical Reaction Network." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/26915.
Full textPh. D.
Rotstein, Evelyn Levy. "Connection, commitment, and community : what motivates teenagers from interfaith families to continue bar/bat mitzvah Jewish education? /." Ann Arbor, MI : University Microfilms, 2006. http://proquest.umi.com/dissertations/preview/3233091.
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