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Zainiyah, Hammimatus. "Hubungan antara usia dan riwayat abortus dengan kejadian plasenta previa Pada ibu bersalin." NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 1, no. 1 (October 21, 2019): 15–20. http://dx.doi.org/10.36089/nu.v1i1.100.
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Jaundice can occur in any baby, eitherbecause of the lack of touch or massage so baby islazy to breastfed making the liver ability to processbilirubin decreased and eventually happenedjaundice. Based on the results of preliminarystudies in BPS Ayu, from 10 infants aged 3-7 days showed 3 babies (30%) did not havephysiological jaundice and 7 infants (70%) hadphysiological jaundice. The purpose of the studywas to analyze the correlation between babymassage with physiological jaundice in infants aged3-7 days at BPS Ayu Surabaya.This study uses an analytical correlation method with cross-sectional approach Collecting data using observation sheets,the data taken on all populations of infants aged 37
days at BPS Ayu Pakal Surabaya by 40respondents and samples taken 36 respondents. The results were analyzed using frequencydistributions using cross tabulation test and Lambda.The results showed that, most of who are massagedwell were 19 respondents (52.8%), most of who arenot jaundiced were 21 respondents (58.3%). Theanalysis Lambda shows that the results of ρ valuewas p value (0.002) <α (0.05) so that Ho is rejected,which means there is correlation between babymassage with pphysiological jaundice in infantsaged 3-7 days at BPS Ayu Surabaya. Expected tomidwifes, or health professionals give advice to mothers on the prevention and treatment theincident of jaundice, one of them is by teachingthe proper baby massage technique.
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Zainiyah, Zakkiyatus. "Hubungan Pijat Bayi Dengan Ikterus Fisiologis Pada Bayi Usia 3-7 Hari." NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 1, no. 1 (October 27, 2019): 1–6. http://dx.doi.org/10.36089/nu.v1i1.98.
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Jaundice can occur in any baby, eitherbecause of the lack of touch or massage so baby islazy to breastfed making the liver ability to processbilirubin decreased and eventually happenedjaundice. Based on the results of preliminarystudies in BPS Ayu, from 10 infants aged 3-7days showed 3 babies (30%) did not havephysiological jaundice and 7 infants (70%) hadphysiological jaundice. The purpose of the studywas to analyze the correlation between babymassage with physiological jaundice in infants aged3-7 days at BPS Ayu Surabaya.This study uses ananalytical correlation method with cross-sectional approach Collecting data using observation sheets,the data taken on all populations of infants aged 37
days at BPS Ayu Pakal Surabaya by 40respondents and samples taken 36 respondents.The results were analyzed using frequencydistributions using cross tabulation test and Lambda.The results showed that, most of who are massagedwell were 19 respondents (52.8%), most of who arenot jaundiced were 21 respondents (58.3%). Theanalysis Lambda shows that the results of ρ valuewas p value (0.002) <α (0.05) so that Ho is rejected,which means there is correlation between babymassage with pphysiological jaundice in infantsaged 3-7 days at BPS Ayu Surabaya. Expected tomidwifes, or health professionals give advice tomothers on the prevention and treatment theincident of jaundice, one of them is by teachingthe proper baby massage technique.
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Shrestha, Sharmila, S. Maharjan, S. Shrestha, and M. A. Petrini. "Knowledge about Neonatal Jaundice among Nepalese Mothers." Journal of BP Koirala Institute of Health Sciences 2, no. 1 (July 23, 2019): 34–42. http://dx.doi.org/10.3126/jbpkihs.v2i1.24965.
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Background: Worldwide, Neonatal Jaundice is one of the most common disorders and causes of avoidable brain damage and physical and mental impairment, and probable death in newborns. It is an important contributor to the high neonatal morbidity and mortality in Nepal. Objective: To assess among mothers the knowledge about neonatal jaundice.
Method: A descriptive cross-sectional study was conducted among 177 mothers in selected village with convenient sampling technique.
Results: Findings revealed that around half of the mothers (49.90%) had low level of knowledge (score <50%), 28.60% mothers had moderate level of knowledge (score 50-75%) and only 22%mothers had adequate level of knowledge (score >75%) regarding neonatal jaundice. A large proportion of mothers (84%) believed that danger sign of neonatal jaundice was unable to feed the baby. Few 11% mothers believed that mental retardation and death was the complication of neonatal jaundice. Few mothers (12%) were aware about the cause of neonatal jaundice. Around 74% believed that exposing the baby to the sunlight is the primary management of neonatal jaundice but only 2%heard about the phototherapy.
Conclusion: Knowledge about neonatal jaundice was low among Nepalese mothers. Awareness should be created among the expecting mothers about neonatal jaundice and encourage them to take preventive measures to avert neonatal mortality and morbidity.
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Amaddeo, Alessandro, Elisa Rubinato, Jurgen Schleef, Damiana Olenik, Domenica Giglia, Federico Marchetti, and Alessandro Ventura. "Obstructive Jaundice in a 3-Month-Old Baby." Journal of Pediatric Gastroenterology and Nutrition 59, no. 3 (September 2014): e31. http://dx.doi.org/10.1097/mpg.0b013e31827e1ec6.
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R., Vikram, and C. S. Balachandran. "Study of hematological indices in neonates admitted with non-obstructive jaundice and its outcome in a tertiary care hospital." International Journal of Contemporary Pediatrics 4, no. 5 (August 23, 2017): 1827. http://dx.doi.org/10.18203/2349-3291.ijcp20173794.
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Background: To study non-obstructive causes and laboratory profile of neonatal hyperbilirubinemia. Design: prospective study.Methods: Selection of cases were done from routine cases reporting to newborn unit in the department of paediatrics, with clinical evidence of jaundice in neonates. Blood group of the mother and baby, Serum bilirubin estimation, Complete blood count with peripheral smear examination, Reticulocyte count, Direct coomb’s test and C-reactive protein of the baby were done.Results: Study includes 89 cases of newborn admitted in our tertiary care institute. Out of 89 neonates, 52 (58.42%) were male while 37 (41.57%) were females. Total number of Pre-term babies was 35 (39.32%). Neonates having low birth weight were 30 (33.7%) and very low birth were 10 (11.23%). Physiological jaundice constituted majority cases. Septicemia was the commonest cause of pathological jaundice and ABO incompatibility is second commonest cause of pathological jaundice. Pre-term and low birth weight babies were having higher levels of serum total bilirubin but the difference was not significant (P >0.05). The rise in serum bilirubin level was found to be more in pathological jaundice as compare to physiological jaundice. Difference was significant statistically with p value of <0.05.Conclusions: Most of the cases were having physiological jaundice although septicemia and ABO-Rh incompatibility were not exceptional. Peak serum bilirubin levels were found to be more among the pathological jaundice. Also, prematurity and low birth weight were having higher levels of serum bilirubin. Special care must be given to them in order to avoid future complications of hyperbilirubinemia.
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Karthikeyan, G., M. Geethanjali, and G. K. Monish. "PROLONGED JAUNDICE IN AN APPARENTLY HEALTHY BABY: A REVIEW." Indian Journal of Child Health 04, no. 03 (September 25, 2017): 285–88. http://dx.doi.org/10.32677/ijch.2017.v04.i03.002.
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Huq, Sazia, Sarder Mahmud Hossain, Syed Mohammad Tanjilul Haque, and Monowar Ahmed Tarafder. "Knowledge Regarding Neonatal Jaundice Management among Mothers: A Descriptive Study Done In a Tertiary Level Hospital of Dhaka City." Anwer Khan Modern Medical College Journal 8, no. 2 (August 23, 2017): 121–27. http://dx.doi.org/10.3329/akmmcj.v8i2.33669.
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Background: Jaundice is the most common clinical condition in the newborn that requires medical attention. This study was carried out in order to assess the knowledge on neonatal jaundice management among the mothers in a selected tertiary level hospital of Dhaka city.Methodology: It was a descriptive type of cross-sectional study. 150 samples were selected by non randomized purposive sampling technique with the administration of a pretested, modified and semistructured questionnaire by face to face interview.Results: Study found that majority of the respondents (76.7%) was in the age group 17-27 years with mean age 23.78±5.397 years. Majority of the respondents (83.3%) had heard about neonatal jaundice previously and 16.7% did not hear about it. Regarding Knowledge on preventive measures of NNJ (neonatal jaundice) 90.6% respondents had knowledge on "Putting jaundiced baby under direct sun light", 62.7% said "Herbal remedies", 48% indicated "Consult with doctor" and 12% had knowledge on "phototherapy". Another major finding from the study was that 7.3% respondents had excellent level of knowledge regarding NNJ, whereas 40.0%, 34.0% and 18.7% had satisfactory, good and poor level of knowledge respectively. The Chi-square test model showed a significant association between previous knowledge of the respondents on NNJ with level of knowledge among the respondents (p= 0.027) and age of the respondents (p=0.012).Conclusion: Awareness should be created among the expecting mothers about neonatal jaundice and encourage them to take preventive measures to avert neonatal mortality and morbidity.Anwer Khan Modern Medical College Journal Vol. 8, No. 2: Jul 2017, P 121-127
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Huo, Yan Ming, Xiao Ying Zuo, Li Na Tong, and Zhi Min Cui. "Automatic Feedback Control System of Detection and Treatment of Infantile Jaundice." Applied Mechanics and Materials 644-650 (September 2014): 326–29. http://dx.doi.org/10.4028/www.scientific.net/amm.644-650.326.
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With the progress of photovoltaic technology and sensor, this paper propose a new automatic feedback control system which based on the color sensor TCS230 and LED flexible lighting equipment to detect and treat infantile jaundice. By testing the severity of the yellowing baby skin, the system makes any response, such as the lights’ intensity and working time. And the final aim is to realize the detection and treatment synchronously for infantile jaundice, promoting the development of intelligent medical treatment.
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Chen, Jun, Mieko Sadakata, Mayumi Ishida, Naoto Sekizuka, and Mitsuko Sayama. "Baby Massage Ameliorates Neonatal Jaundice in Full-Term Newborn Infants." Tohoku Journal of Experimental Medicine 223, no. 2 (2011): 97–102. http://dx.doi.org/10.1620/tjem.223.97.
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Said, Norimah. "Postnatal mother: Knowledge and attitude towards Neonatal Jaundice (NNJ)." Elevate The International Journal of Nursing Education, Practice and Research 1, no. 1 (July 24, 2018): 40–45. http://dx.doi.org/10.25077/elevate.1.1.40-45.2018.
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ABSTRACT: Neonatal jaundice (NNJ) is a pathological situation where an imbalance between bilirubin production and excretion is present due to a multitude of factors. The objective of this study is to identify the number of post-natal mothers who had received education and their attitude on neonatal jaundice. A cross-sectional design was carried out among 131 posts natal mother. The questionnaire was given to the respondents. Results show there is a significant relationship between knowledge and attitude towards neonatal jaundice among postnatal mother. A part 50% of the mothers have a neutral attitude, 27.5% have a positive attitude and 8.4% have a negative attitude towards neonatal jaundice. The outcome of this study showed that most of them others have good knowledge on neonatal jaundice. However, they may fear invasive procedures such as taking blood from their baby. Future studies should focus on attitude towards traditional treatments among postnatal mothers.
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S, Sri Wahyunie, Nurhayana Sennang, D. Daud, and Mansyur Arif. "MALARIA KONGENITAL." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 21, no. 2 (March 27, 2018): 202. http://dx.doi.org/10.24293/ijcpml.v21i2.1109.
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Congenital Malaria is an infectious disease caused by the malaria parasite that is transmitted from mother to child through theplacenta during pregnancy or at delivery. Clinical manifestations which may arise due to Plasmodium infection are: the irritability,fever, anaemia, jaundice and hepatosplenomegaly. The incidence of congenital malaria according to the National Basic Health Research2010 is only about 0.3%. Forty two days old male baby with the main complaints fever and pale since he was three (3) weeks old. Fromthe physical examination the reviewer found anaemia, jaundice and splenomegaly. Plasmodium vivax was detected by serologic andmicroscopic examination. From the pregnancy history of mother the reviewer found that at the age of seven (7) months of pregnancyshe suffered from malaria caused by Plasmodium vivax the same as the type of Plasmodium infected the baby. The baby was born innon malaria endemic area which enhanced the diagnosis of congenital malaria of this patient. The patient was fully recovered aftertreated with dehydroartemisin piperaquin and the reviewer reported one case of congenital malaria, forty twodays old male baby. Thediagnosis was made based on the malaria history of mother at seven (7) month of pregnancy, the serologic and microscopic examinationfrom the patient blood and the baby was born in a non malaria endemic area. The prognosis of patient with congenital malaria causedby Plasmodium vivax generally was good. The clinical condition was improved and fully recovered after treated with dehydro-artemisinpiperaquin.
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Sarici, Serdar Umit, Esad Köklü, and Oguzhan Babacan. "Comparison of Two Transcutaneous Bilirubinometers in Term and Near-Term Neonates." Neonatal Network 33, no. 3 (2014): 138–42. http://dx.doi.org/10.1891/0730-0832.33.3.138.
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Purpose: Determination of bilirubin levels is performed for many newborns in the first days of life, and several different transcutaneous bilirubinometers are available. We aimed to determine whether transcutaneous bilirubin measurement, as performed using Jaundice Detector JH20-1C, a new device, correlates with Minolta/Hill-Rom Air-Shields Transcutaneous Jaundice Meter model JM-103.Design and Sample: The study was performed on term or near-term newborn infants who underwent transcutaneous bilirubin measurements as part of their normal care. The study group consisted of 585 newborn infants with gestational ages ranging from 35 to 42 weeks, coming from an uneventful pregnancy. In this prospective study, bilirubin concentrations were determined with two different transcutaneous bilirubinometers.Main Outcome Variable: In 585 infants, the correlation coefficient for Jaundice Detector JH20-1C versus Minolta Air-Shields Jaundice Meter model JM-103 was .965 (p < .0001). The mean (± standard deviation) difference between the Jaundice Detector JH20-1C versus Minolta Air-Shields Jaundice Meter model JM-103 was 0.26 ± 0.95 mg/dL. Results showed the Jaundice Detector JH20-1C to have an acceptable level of intradevice imprecision (r = .978, p < .0001, mean differences .0158 ± .871 mg/dL).Results: Jaundice Detector JH20-1C showed the good performances of intradevice and interdevice imprecision in comparison with Minolta/Hill-Rom Air-Shields Transcutaneous Jaundice Meter model JM-103. Jaundice Detector JH20-1C may be suitable for screening term or near-term newborn infants for jaundice in the well-baby nursery or maternity ward.
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Chen, Huan-wei, Feng-jie Wang, Jie-yuan Li, Eric C. H. Lai, and Wan Yee Lau. "Hepatocellular Carcinoma Presenting with Obstructive Jaundice during Pregnancy." Case Reports in Surgery 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/502061.
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Introduction. Both hepatocellular carcinoma (HCC) presenting during pregnancy and HCC presenting with obstructive jaundice due to a tumor cast in the biliary tract are very rare. The management of these patients remains challenging.Presentation of Case. A 23-year-old lady presented with obstructive jaundice at 38 weeks of gestation. Investigations showed HCC with a biliary tumor thrombus. She received percutaneous transhepatic biliary drainage (PTBD) and caesarean section. Right hepatectomy, extrahepatic bile duct resection, and left hepaticojejunostomy were carried out when the jaundice improved. The postoperative course was uneventful. She was discharged home on postoperative day 10. Histopathology showed HCC with a tumor thrombus in the bile duct. The surgical margins were clear. One year after surgery, the mother was disease-free and the baby was well.Conclusion. With proper management, curative treatment is possible in a pregnant patient who presented with obstructive jaundice due to a biliary tumor thrombus from HCC.
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Shirzadfar, Hamidreza, and Kowsar Sheikhi. "Novel Design and Evaluation of an Automatic and Portable Phototherapy Device Using for Newborn Jaundice Treatment." Recent Research in Endocrinology and Metabolic Disorder 1, no. 1 (December 14, 2019): 22–31. http://dx.doi.org/10.33702/rremd.2019.1.1.5.
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Jaundice in infants is one of the most common diseases at birth. In preterm infants, the risk is more than 80%, and in term infants, the rate is reduced to about 60%. One of the most effective and low-risk ways to treat neonatal jaundice is the use of light therapy or phototherapy. Fluorescent lamps, tungsten halogen lamps, LEDs, optical fibers and etc are used in these devices. Bilirubin reacts to green light and blue light. The green light's wavelength is in the range of 570-495 nm. The blue light has a wavelength of 495-450 nm and an absorption range of 450 nm. Studies have found that the best light for phototherapy devices is a light that has the wavelength of 400 to 520 nm, and because the blue light absorption rate is about 450 nm, so it is used in phototherapy. In addition to its proper absorption rate, it also has antimicrobial activity against bacteria. It is difficult to determine the exact duration of the phototherapy, because each infant has his/her specific conditions and the exact duration cannot be determined generally. Phototherapy should be continued until the bilirubin level in the baby's blood is sufficiently reduced, monitored by the supervision, and does not pose a threat to the baby. Phototherapy devices have different types, each with advantages over their predecessors. In existing models, because of their unique features like high sensitivity to bilirubin reduction, higher power, and efficiency, lighter, lower heat generation, lower cost and longer life devices, LED light sources are widely used in phototherapy devices. According to all the studies, we are looking for a device with proper coverage, portability, and moving the baby with the device without separating the baby from the baby as well as providing a quiet space for the mother and baby away from the hospital environment.
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Kalraiya, Ashish, Pankaj Gyanani, Shiv Ram Krishna Dubey, Vijaya Beohar, and Pramila Verma. "Clinico-etiological profile of neonates admitted with jaundice in a tertiary care NICU of Central India." International Journal of Contemporary Pediatrics 5, no. 3 (April 20, 2018): 1049. http://dx.doi.org/10.18203/2349-3291.ijcp20181540.
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Background: Hyperbilirubinemia is a common problem and, in most cases, a benign problem in neonates. Jaundice is observed during the 1st week of life in approximately 60% of term infants and 80% of preterm infants.Methods: In present study, total 187 newborns were enrolled prospectively over one and half year of study period from November 2015 to April 2017. Detailed patient information was taken at the time of admission in NICU. In this study all the newborns with age less than 28 days were included who had clinical jaundice, ascertained by Kramer’s criteria and confirmed by biochemical methods. The investigations done were Serum bilirubin (total, direct and indirect) complete blood picture, reticulocyte count, G6-PD estimation (qualitative), Coombs' test, peripheral smear examination, blood group (ABO,Rh) of the mother and baby, CBC,CRP, thyroid function test.Results: Total 187 newborns were enrolled for study. Maximum number of the babies have a pathological jaundice 108 (57.7%) whereas 79 (42.24%) were found to have exaggerated physiological jaundice. The commonest causes of pathological jaundice were found to be septicemia 63 (33.68%) followed by ABO incompatibility 25 (13.36%). Most of the babies had onset of jaundice between 24-72 hours (86.6%).Conclusions: Health care providers working with neonates play a key role in identifying and assessing neonates at risk for pathologic jaundice. Parents counseling is required for bringing their babies early to healthcare centre preventing acute bilirubin encephalopathy and subsequent kernicterus.
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Kusika Saputra, Nicko Pisceski, and Putri Sri Lasmini. "Pengaruh Inisiasi Menyusu Dini terhadap Waktu Pengeluaran dan Perubahan Warna Mekonium Serta Kejadian Ikterik Fisiologis." Jurnal Ilmu Kedokteran 9, no. 2 (December 29, 2017): 87. http://dx.doi.org/10.26891/jik.v9i2.2015.87-94.
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One of the government’s efforts through the Millennium Development Goals (MDGs) in 2010 in reducing the infantmortality rate in Indonesia is improving infants nutrition and promote exclusive breastfeeding early breastfeedinginitiation. Early initiation of breastfeeding has many benefits for both mother and baby. This study aimed to comparemeconium spending time and meconium color change and the incidence of physiologic jaundice in infants whoreceived and did not receive early breastfeeding initiation (IMD). This study was a cross sectional analytical studyconducted at the Achmad Mochtar Hospital Bukittinggi. Forty-two maternity patients divided into two groups thatprovide IMD and unprovide IMD group to her baby. In each group assessed first meconium spending time in minutes,the time change meconium original colour of dark green to yellow and counted since birth in hours and the incidenceof physiologic jaundice in infants. All babies kept getting breastfeeding. There were no significant differences in themean time the first meconium spending time in both groups (131.42 minutes and 163.33 minutes, p> 0.05). There aresignificant differences in the mean time meconium colour changes from dark green to yellow (50.14 hours and 94.36hours, p <0.05). Early initiation of breastfeeding also lowers the incidence of physiological jaundice were significantly(p <0.05). Early initiation of breastfeeding did not affect spending time first meconium but accelerate meconiumcolor changes from dark green to yellow. Early initiation of breastfeeding also lowers the incidence of neonataljaundice.
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Suresh, Indrajit, Jyotsna AS, Meenakshi Katyal, Sruthi Balla, Suryaprakash R. Kothe, and Nirbheek S. "Jaundice in a baby with self-improving collodion ichthyosis and ALOX12B mutation- a challenging scenario." International Journal of Research in Dermatology 1, no. 1 (December 25, 2015): 28. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20160355.
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Autosomal recessive congenital ichthyoses are a heterogeneous group of rare cornification diseases. Genetic mutations are responsible for the condition, with some causing a relatively milder phenotype such as ‘self-improving collodion ichthyosis’. In most cases, affected babies are born with a thick parchment like membrane covering their body. These babies may have a problematic postnatal course, and are prone to complications. The authors present the report of a newborn collodion baby afflicted with ALOX12B mutation, who had a challenging post natal course. Difficulties in feeding, temperature control, hydration and electrolyte balance were encountered and required precise monitoring and formulation of an effective treatment strategy. Treatment of jaundice in the baby also presented a unique challenge, which was successfully managed.
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Gupta, BK, N. Chaudhary, BD Bhatia, and Binod Gupta. "Non invasive trans-cutaneous bilirubin as a screening test to identify the need for serum bilirubin assessment in healthy term neonates." Journal of Universal College of Medical Sciences 1, no. 4 (January 12, 2014): 17–21. http://dx.doi.org/10.3126/jucms.v1i4.9567.
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INTRODUCTION: Hyperbilirubinemia is a common problem in the neonates. It can progress to develop kernicterus unless intervention is initiated. Severity of jaundice and decision for management are usually based on total serum bilirubin (TsB) estimation which technique and results closely correlates with total serum bilirubin levels. OBJECTIVES: To compare the accuracy of visual assessment of jaundice by single trained observer based on Kramer's index with total serum bilirubin levels in healthy term neonates. To compare accuracy of non invasive bilirubin assessment with serum bilirubin levels, to compare trans-cutaneous bilirubin assessment on different sites (forehead and sternum) and to develop a cutoff point oftrans-cutaneous bilirubin level for serum bilirubin assessment. METHODS: This prospective study was conducted in the Neonatal unit of the department of Paediatrics at Kasturba Hospital ,Manipal. Study period was from October 2007 to June 2008. Clinical assessment of jaundice was done in healthy term neonates by observer (Trained Paediatric Post Graduate Resident) based on Kramer's index. Transcutaneous bilirubin assessment was done on the forhead and sternum of each baby using JM-103 Minolta. Air shields bilirubino meter. Serum bilirubin level was measured within 30 minutes of the clinical assessment for each baby. RESULTS: This study included 187 healthy term neonates. The mean birth weight was 2856.83gm ± 493.89gm and mean gestation was 38.25+ 1.030 SD. Clinical assessment and Transcutaneous bilirubin(TcB) significantly correlated with total serum bilirubin (TsB), with correlation co-efficient of 0.757 and 0.801 respectively (p 0.0001). Transcutaneous bilirubin assessment over forehead showed a tendency to under estimate total serum bilirubin, with mean difference of-0.31 mg/dl, SD 1.75 mg/dl with 95% confidence interval ofthe mean -0.60 and -0.02 mg/dl (p value 0.05).Transcutaneous bilirubin assessments between 10 mg/dl to 15 mg/dl correlated accurately with total serum bilirubin levels avoiding blood sampling. CONCLUSION: Trained observer clinical assessment of jaundice can be used for screening neonatal jaundice. Non invasive transcutaneous bilirubin assessment has demonstrated significant accuracy with serum bilirubin level estimates between 48 hours to 7 days on two different sites forehead and sternum. DOI: http://dx.doi.org/10.3126/jucms.v1i4.9567 Journal of Universal College of Medical Sciences (2013) Vol.1 No.04: 17-21
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Muliawati, Ni Kadek, I. Gusti Ayu Trisna Windiani, Anak Agung Sagung Sawitri, and Luh Seri Ani. "Time of colostrum discharge of more than six hours as a risk factor for physiological jaundice in neonates." Public Health and Preventive Medicine Archive 7, no. 1 (July 31, 2019): 44. http://dx.doi.org/10.15562/phpma.v7i1.193.
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Background and purpose: Neonatal jaundice is both a physiological and pathological condition. Neonatal physiological jaundice occurs within 3-5 days after the baby is born. Publications about colostrum and neonatal jaundice are still limited. This study aims to determine the risk of the onset of colostrum discharge of more than 6 hours to physiological jaundice in neonates.Methods: A case control study was conducted at the Sanglah General Hospital in Denpasar from August to December 2017. The number of cases was 55 neonates with physiological jaundice and the number of controls was 55 neonates without physiological jaundice. Cases and controls were selected by consecutive sampling. The occurrence of physiological jaundice was obtained by direct observation and the degree of jaundice was determined based on the division of Kramer's body zone. Neonates with the Kramer grades I and II at the age of 3-5 days were classified as experiencing physiological jaundice (as cases) and neonates with a Kramer grade of 0 at the age of 3-5 days were classified as not jaundice (as controls). Cases were matched with controls by sex and age of the neonates. Data on maternal socio-demographic characteristics, onset of colostrum discharge, early breastfeeding initiation and 24-hour breastfeeding frequency were obtained by interview; data on jaundice was obtained by observation while mode of delivery, parity, history of pre-eclampsia, prematurity, neonatal birth weight, history of birth trauma (cephalic hematoma), history of asphyxia and major congenital abnormalities were obtained from medical records. Multivariate analysis with binary logistic regression was carried out to determine the adjusted odds ratio (AOR) of the onset of colostrum discharge.Results: The characteristics of cases and controls were found to be similar in terms of maternal education, neonatal age and sex, parity and pre-eclampsia history. Significant outset of colostrum >6 hours was found to be associated with physiological jaundice with AOR=2.57 (95%CI: 1.04-6.37). In this study, variables that were not found to be the risk factors of physiological jaundice in neonates were: cesarean delivery (AOR=0.36; 95%CI: 0.09-1.41; p=0.14), breastfeeding frequency within 24 hours (AOR=2.20; 95%CI: 0.47-10.23; p=0.31) and early breastfeeding initiation (AOR=0.71; 95%CI: 0.19-2.59; p=0.60)Conclusion: Onset of colostrum discharge >6 hours is a risk factor for neonatal jaundice. Efforts should be made to accelerate the release of colostrum in order to prevent neonatal jaundice.
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Yousuf, Rabeya, Nurasyikin Yusof, Tang Yee Loong, Suria Abdul Aziz, and Leong Chooi Fun. "A Case Report of Haemolytic Disease of Foetus and Newborn due to Anti-E Antibody in a Primigravida Patient." Bangladesh Journal of Medical Science 15, no. 1 (April 11, 2016): 139–41. http://dx.doi.org/10.3329/bjms.v15i1.27177.
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Anti-E antibody is one of the frequently encountered alloantibody of the Rh blood group system; however, it is seldom implicated in haemolytic disease of the foetus and newborn (HDFN). This case report describes a mild HDFN due to anti-E antibody in a full term baby-girl born to a primigravida patient. The baby developed jaundice on the first day of life. Blood group of both mother and the baby was B positive and Rh phenotype was CDe/CDe (R1R1) and CDe/cDE (R1R2) respectively. Anti-E and anti-c was identified in the mother while babys blood showed weak positive Direct Antiglobulin Test with anti-E identified from the babys serum. The baby was started on phototherapy and was discharged well on day-6. Although this was a mild HDFN, we would like to highlight the importance of antenatal screening for pregnant mothers. The antibody screening for Rh-positive mothers is not a routine practice in many centers in Malaysia due to cost-benefit constraints. However, we would like to suggest to include the antenatal red cell antibody screening test for all pregnant mothers at least during the 1st antenatal booking to enable early detection of alloantibody which may cause HDFN, thus enable close monitoring of foetus and initiate early management as needed.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.139-141
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Patel, Avinash, Karan Saradava, and Hasmukh Chauhan. "Clinical profile and aetiological factors of neonatal jaundice from a rural area of Kutch, Gujarat, India." International Journal of Contemporary Pediatrics 8, no. 1 (December 23, 2020): 143. http://dx.doi.org/10.18203/2349-3291.ijcp20205521.
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Background: Etiology of hyperbilirubinemia is not only crucial for optimal management of the patient but also it may have implications for subsequent pregnancies. The objective of this study was to study the clinical profile and the underlying aetiological factors leading to neonatal jaundice in this rural setting of Kutch District, Gujarat, India.Methods: This prospective observational study was conducted in the neonatal intensive care unit (NICU) and Post Natal ward Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat. Total of 150 cases were enrolled for the study. Blood grouping and Rh typing of baby and mother were done. Cord blood bilirubin and haemoglobin, direct coomb's test (DCT) and bilirubin monitoring were done whenever there was a setting for Rh incompatibility.Results: Among 150 neonates studied, majority had birth weight between 2501g and 3000g. Only 21 babies had birth weight <2.5kg (14%) (Table 2). Of the 150 neonates 85 were males and 65 were females.Conclusions: This study concludes that physiological jaundice is the most common cause of neonatal jaundice in our hospital. This is followed by ABO incompatibility, sepsis, Rh incompatibility and idiopathic cases.
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Ogbe, Zemichael, Amanuel Kidane Andegiorgish, Aradom Habteab Zeray, and Lingxia Zeng. "Neonatal Hypernatremic Dehydration Associated with Lactation Failure." Case Reports in Critical Care 2020 (November 15, 2020): 1–5. http://dx.doi.org/10.1155/2020/8879945.
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Hypernatremic dehydration secondary to lactation failure remains a potentially life-threatening condition in countries where advanced laboratory investigations are scarce. An 11-day term baby with excessive weight loss (33.6%), reduced urine output, fever, jaundice, doughy skin, opisthotonus posturing, and tachycardia with poor perfusion was presented to our neonatal care. The baby was diagnosed with shock with hypernatremic dehydration. An initial bolus of 20 ml/kg of N/S was repeated 3 times (each over 20 minutes), i.e., a total of 204 ml was given over 1 hr, until the vital signs were normalized to PR-145, RR-45, T-37.2°C, SPO2-100%, and CRT < 3 seconds, and the baby began to void urine. Free water deficit and sodium excess was managed by gradual and slow correction over 72 hours to prevent cerebral oedema and neurologic sequelae. The baby required reconstituted solutions of 5% D/W + 1/2 N/S at a rate of 27 ml/hr for 72 hrs. Sepsis and hyperbilirubinemia were treated with antibiotics and phototherapy. Management of symptomatic hypernatremic dehydration must be considered in settings with inadequate laboratory facilities.
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Ochoga, M. O., E. E. Eseigbe, A. M. Onoja, M. Aondoaseer, B. N. Samba, R. O. Abah, and R. Abdallah. "Pattern of Blood Transfusion in the Special Care Baby Unit of Benue State University Teaching Hospital in Makurdi North-Central Nigeria." JOURNAL OF RESEARCH IN BASIC AND CLINICAL SCIENCES 2, no. 1 (June 26, 2021): 9–16. http://dx.doi.org/10.46912/jrbcs.93.
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Blood transfusion is a life-saving procedure in which whole blood or parts of blood are introduced into a patient's bloodstream intravenously. The need maybe due to physiological or pathological causes. The objective of this study was to document the pattern and indications for blood transfusion at the Special Care Baby Unit of the Benue State University Teaching Hospital (BSUTH), Makurdi. This study was a retrospective review of 126 neonates who received blood transfusion at the Special care baby unit of BSUTH from 1st January 2015 to 31st December 2019. Data was retrieved from patient's medical records and analyzed using IBM SPSS version 23. A total of 1142 neonates were admitted over the study period and 126 had blood transfusion giving a prevalence of 11.0%. Male/Female ratio of 1.57:1.Mean (±SD) Birth weight and gestational age (GA) were 2.23±0.82Kg and 35.48 ±3.95 weeks respectively. Exchange blood transfusion was the most frequent 53(42.1%) type of blood transfusion. The most common indications for blood transfusion were anaemia of prematurity, sepsis and severe neonatal jaundice. A hundred and twelve (88.9%) who received transfusion were discharged while 4(3.2%) died. The rate of blood transfusion was low, while severe neonatal jaundice and anaemia were the main indications for blood transfusion in this study. Exchange blood transfusion was the main type of transfusion.
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Sofyanita, Eko Naning, Endang Susilowaty, and Roni Afriansya. "The Effect of Light Exposure to Bilirubine Levels on Serum Jaundice Infant in Hospital of Islamic NU Demak." Borneo Journal of Medical Laboratory Technology 3, no. 1 (October 31, 2020): 168–71. http://dx.doi.org/10.33084/bjmlt.v3i1.1766.
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Bilirubin is a substance formed from the normal breakdown of erythrocytes in the body so that it gives a yellow color to the stool and urine. The test of bilirubin in the laboratory must avoid exposure to light, which can cause decreased serum bilirubin levels by up to 50% in 1 hour due to disruption of the bilirubin's stability. This study is a cross-sectional analytic study of primary data using 30 samples of jaundice baby serum and direct and total bilirubin test. Data collection was conducted from the primary data by a direct test using 40 samples of infant jaundice and test of direct bilirubin and total bilirubin using methods Dichlorophenyl Diazonium. The results of the tests of 40 samples can result in the mean levels of total bilirubin were exposed to the light of 8.58 mg/dl and were not exposed to light 12,67mg /dl. Direct bilirubin levels mean that exposure to light is 3.98 mg/dl. In contrast, the unexposed light of 8.71 mg/dl, so that it can be concluded that the levels of total and direct bilirubin in serum jaundice infants exposed to lower light compared with those not exposed to light.
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Turnbull, Victoria, and Julia Petty. "Early onset jaundice in the newborn: understanding the ongoing care of mother and baby." British Journal of Midwifery 20, no. 9 (September 2012): 615–22. http://dx.doi.org/10.12968/bjom.2012.20.9.615.
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Dalili, Hosein, Sanaz Sheikhi, Mamak Shariat, and Edith Haghnazarian. "Effects of baby massage on neonatal jaundice in healthy Iranian infants: A pilot study." Infant Behavior and Development 42 (February 2016): 22–26. http://dx.doi.org/10.1016/j.infbeh.2015.10.009.
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Suradi, Rulina, Esther H. Situmeang, and Taralan Tambunan. "The association of neonatal jaundice and breast-feeding." Paediatrica Indonesiana 41, no. 2 (April 30, 2001): 69. http://dx.doi.org/10.14238/pi41.2.2001.69-75.
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To examine the prevalence of jaundice in neonates and its association with breast-feeding, we studied 100healthy breast-fed baby boys during the first 3 - 5 days after birth, delivered in Dr. Cipto Mangunkusumo Hospital. This wasan analytical, cross-sectional study performed prospectively. The study was conducted from April, 1, 1999 to October 15,1999. Jaundice was detected in 94 out of 100 infants (94%). Breast-feeding jaundice was encountered in 26 infants (28%)namely infants whose bilirubin levels was >12 mg/dL by day 3 (CI 95% : 19;37%). Most infants showed bilirubin levels on daytwo, three and five of 6 – 10 mg/dL (62%), 6 – 10 mg/dL (35%) and 12 – 15 mg/dL (34%), respectively. Several factors foundto be contributing to the occurrence of breast-feeding jaundice included : a. breast-feeding frequency (r :- 0.83, p < 0.01), b.mean breast-feeding duration : infants breast-fed for more than 30 minutes have consequences its breast-feeding frequencywas less in compared with those breast-fed in less than 30 minutes. c. time of meconium passage (p< 0.05), meconiumpassage in the first hours after birth played an important part in reducing enterohepatic circulation, d. fecal weight (r =-0.87,p < 0.01), feces retained in the intestine its bilirubin would be deconjugated and reabsorbed subsequently . e. weight loss (p< 0.05). In 11 infants who received blue light therapy there were no abnormalities both in physical and laboratory examinations.
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Begum, Nargis Ara, and Sharmin Afroze. "An Overview of Neonatal Unconjugated Hyperbilirubinemia and It’s Management." Bangladesh Journal of Child Health 42, no. 1 (June 17, 2018): 30–37. http://dx.doi.org/10.3329/bjch.v42i1.37048.
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Neonatal hyperbilirubinemia is the most common clinical condition in the newborn requiring hospital readmission. About 60% of term and 80% of preterm infants develop jaundice during 1st week of life. Unconjugated hyperbilirubinemia occurs mostly due to increased hemolysis, decreased hepatic clearance, enterohepatic circulation, immaturity, blood group incompatibility and infections. Evaluation of neonatal jaundice is done based on history, age of onset of jaundice and physical examination findings which is necessary for proper management. Otherwise significant hyperbilirubinemia may endanger life of the baby and may lead to acute and subsequently chronic bilirubin encephalopathy. There are many diagnostic tools those help to detect jaundice such as Kramer’s rule, transcutaneous bilirubinometer, Bilichecker apps and smartphone apps. Besides these BIND score added a new dimension in diagnosis of acute bilirubin encephalopathy which can be confirmed by measuring bilirubin – albumin ratio in blood. Management of unconjugated hyperbilirubinemia includes: Phototherepy, Exchange transfusion are two major effective therapeutic modalities available today. Additional options include Pharmacotherapy in the form of phenobarbital and intravenous immunoglobulin. Each therapy has its pros and cons. Even there is dilemma in many therapeutic conditions like role of prophylactic phototherapy in preterm neonates, role of sunlight etc. As pediatricians have to deal cases with unconjugated hyperbilirubinemia frequently, so an updated knowledge is required. From this concern we reviewed issues on neonatal unconjugated hyperbilirubinemia and compiled for better understanding of the condition.Bangladesh J Child Health 2018; VOL 42 (1) :30-37
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Rhomadona, Shinta Wurdiana, and Melyana Nurul Widyawati. "Analisis Aktivitas Kontraksi Uterus dan Perinatal Outcome pada Ibu Bersalin dengan Induksi." Jurnal Keperawatan Silampari 2, no. 2 (May 13, 2019): 53–65. http://dx.doi.org/10.31539/jks.v2i2.517.
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The purpose of this study is to analyze the activity of uterine contractions and perinatal outcomes in mothers who give birth by induction. The method of this study was a prospective observational descriptive design of 20 women with induction whose contractions were monitored every 15 minutes for 10 minutes by palpation and recorded perinatal outcomes. The results of this study show that the frequency and duration trends in successful induction deliveries tend to increase while those that fail tend to be constant. Successive average frequency and duration of successful induction 4.2 times / 10 minutes and 45.09 seconds. Whereas the failed induction was 1.92 times / 10 minutes and 25.54 seconds. In conclusion, most BLB is between 2500-4000 grams. The majority sex is female. Apgar score condition between 7-10. 1 baby serotinus and no baby with pathological jaundice.
Keywords: Activity of Uterine Contraction, Labor Induction, Perinatal Outcome
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LNU, Pushpalatha, G. Naga Vasanthalakshmi, and Sirisha LNU. "Successful Management of Early Onset Rh-immunized Pregnancy." Journal of South Asian Federation of Obstetrics and Gynaecology 7, no. 3 (2015): 202–4. http://dx.doi.org/10.5005/jp-journals-10006-1357.
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ABSTRACT Rh-isoimmunization still remains an important preventable cause of perinatal mortality and morbidity. The improved perinatal outcome in sensitized patients is mainly attributed to application of color Doppler ultrasonography as a noninvasive method of detecting and monitoring fetal anemia and fetal wellbeing, improvement in ultrasonography machines and fetal interventional techniques and better neonatal intensive care facilities. Here, we present a case G3P2L1D, Rh negative with previous lower segment cesarean section (LSCS), diagnosed to be indirect Coomb's test (ICT) positive (1:64) at 9 weeks. She was followed up with serial ICT titers every 2 weeks along with ultrasonography (USG) and Doppler. Fetal anemia was detected with middle cerebral artery (MCA) Doppler at 27 weeks and same treated with intrauterine transfusions twice. She was diagnosed to have gestational diabetes mellitus and treated for the same. Patient then delivered at 36 weeks and 5 days by emergency LSCS in labor, a healthy girl baby, 3.07 Kg. Postnatally, baby developed jaundice and was treated with double light phototherapy. Baby also developed anemia subsequently 3 days after birth and was treated with one dose of intravenous (IV) immunoglobulin. Baby with mother were discharged on postoperative day 5 in good health. How to cite this article Vasanthalakshmi GN, Sirisha, Pushpalatha. Successful Management of Early Onset Rhimmunized Pregnancy. J South Asian Feder Obst Gynae 2015;7(3):202-204.
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Begum, Nargis Ara, Khorshed Alam, Anamika Shaha, Md Sohel Showmik, Runa Laila, Shahnaz Parvin, Abdur Rahman, and Mizanur Rahman. "Transcutaneous Billirubinometry: A Useful Screening Tool for Neonatal Jaundice in Term and Near Term Babies - A Hospital Based Study." Bangladesh Journal of Child Health 39, no. 3 (February 13, 2017): 116–22. http://dx.doi.org/10.3329/bjch.v39i3.31575.
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Background: Hyperbilirubinemia is a common problem in newborn. Most of the cases are benign but severe hyperbilirubinemia can lead to kernicterus and brain damage which is preventable. The gold standard to asses neonatal hyperbilirubinaemia is serum bilirubin measurement. Unfortunately, this procedure is invasive, painful and time consuming. As the consequence of missing severe hyperbilirubinemia is serious, there is a constant search to find out a safe method to detect jaundice. Transcutaneous bilirubinometry offers objective method of assessing degree of jaundice reducing subjectivity of clinical assessment.Objective: To evaluate the relationship between transcutaneous bilirubin (TcB) and total serum bilirubin (TSB) and assess whether transcutaneous bilirubinometry can be used as a valid screening method for detecting jaundice in term and late preterm babies.Method: A prospective cross-sectional study was performed in well baby nursery of United Hospital Limited, Dhaka from January 2013 to December 2013. Healthy term and late pre term newborn of ?35 wk gestation with clinical evidence of jaundice were included in the study. Total serum bilirubin was measured by Dichlorophenyl Diazonin method and transcutaneous bilirubinometer (JM-103) was used to measure transcutaneous bilirubin (TcB) level.Result: A total of 116 paired samples were analyzed and found strong correlation between TcB and TSB (correlation coefficient 0.8, mean difference 0.83, SD± 1.96 and 95% CI 0.6 to 1.06). Post natal age has significant association with TcB (p value 0.01) and TSB (p value 0.031). Requirement of phototherapy in both group were also significant (p value <0.001). TcB value of 11 mg/dl was chosen as cut off point corresponding TSB level 13 mg/dl with sensitivity 90% and specificity 71%. Above this level indicate need for blood sampling to take appropriate therapeutic measure.Conclusion: Transcutaneous billirubinometry is a non-invasive and valid screening tool for assessing jaundice in newborn.Bangladesh J Child Health 2015; VOL 39 (3) :116-122
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Cho, Hyun-Seok, Young Kwang Choo, Hong Jin Lee, and Hyeon-Soo Lee. "Transient carnitine transport defect with cholestatic jaundice: report of one case in a premature baby." Korean Journal of Pediatrics 55, no. 2 (2012): 58. http://dx.doi.org/10.3345/kjp.2012.55.2.58.
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Ochoga, M. O., R. O. Abah, A. Michael, L. E. Yaguo Ide, R. Onalo, A. Idoko, A. Idoko, S. N. Okolo, and A. Onyemocho. "Retrospective assessment of neonatal morbidity and mortality in the special care baby unit of a private health facility in Benue State, North Central Nigeria." Nigerian Journal of Paediatrics 47, no. 4 (August 28, 2020): 353–57. http://dx.doi.org/10.4314/njp.v47i4.9.
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Background: Newborn morbidity and mortality have remained unacceptably high in developing countries despite consistent efforts at controlling the scourge. Unlike in developed countries where neonatal mortality rate ranges between 1 and 5 per 1000 live births, average neonatal mortality rate in Nigeria is 36 per 1000 live births. The majority of the causes of death are largely preventable with timely low cost interventions. This study was structured to determine the pattern of morbidity and mortality amongst babies admitted in the Special Care Baby Unit of Madonna hospital Makurdi, Nigeria.Methods: The records of neonates admitted into the Special Care Baby Unit (SCBU) over a tenyear period (2005-2015) were retrospectively reviewed. Information obtained included the sex, age at admission, gestational age, birth weight, reasons for admission and outcome of treatment.Results: A total of 1,121 babies were admitted during the period under review. The male female ratio was 1.2:1.The majority of the babies were aged between 2-7 days with a mean 6.17.+ 7.01 The mean weight on admission was 2807+907g. Neonatal sepsis, jaundice, low birth weight and birthasphyxia were the most common morbidities. The overall mortalityrate was 14.1%; however, proportionate mortality due to low birth weight was highest (26.4%), followed by tetanus (23.5%), asphyxia (20.8%), Respiratory tract infection (13.8%), meningitis (13.3%), sepsis (10.3%), jaundice (9.6%), and diarhoea (4.0%)Conclusion: Neonatal mortality rate in the study was high. The major causes of admission are preventable. Strengthening perinatal care, emergency obstetric care services and neonatal resuscitation skills are necessary to reduce the neonatal mortality.
Key words: Neonate, Morbidity, Mortality, Nigeria
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Kadek, Kadek, and S. Darmadi. "Congenital Rubella Syndrome Based on Serologic and RNA Virus Examination." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 13, no. 2 (February 22, 2017): 63. http://dx.doi.org/10.24293/ijcpml.v13i2.673.
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Rubella infection with occurs during pregnancy, especially during the first trimester often caused by Congenital Rubella Syndrome (CRS). CRS can resulting abortions, miscarriages, stillbirth, and severe birth defects. The baby diagnosed with CRS when characterized by signs or symptoms from the following two categories A (Cataracts/congenital glaucoma, congenital heart disease (most commonly patent ductus arteriosus or peripheral pulmonary artery stenosis), loss of hearing, pigmentary retinopathy) or one categorie A and one catagorie B (Purpura, splenomegaly, jaundice, microencephaly, mental retardation, meningoencephalitis, radiolucent bone disease. Laboratory confirmation can be obtained by any of the following: virus isolation, serologi test (pasif hemaglutination, latex agglutination test, hemaglutination inhibisi, Flouresence immunoassay, Enzyme immunoassay), RNA test.
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Kadek, Kadek, and S. Darmadi. "GEJALA RUBELA BAWAAN (KONGENITAL) BERDASARKAN PEMERIKSAAN SEROLOGIS DAN RNA VIRUS." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 13, no. 2 (March 15, 2018): 63. http://dx.doi.org/10.24293/ijcpml.v13i2.885.
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Rubella infection with occurs during pregnancy, especially during the first trimester often caused by Congenital Rubella Syndrome(CRS). CRS can resulting abortions, miscarriages, stillbirth, and severe birth defects. The baby diagnosed with CRS when characterizedby signs or symptoms from the following two categories A (Cataracts/congenital glaucoma, congenital heart disease (most commonlypatent ductus arteriosus or peripheral pulmonary artery stenosis), loss of hearing, pigmentary retinopathy) or one categorie A andone catagorie B (Purpura, splenomegaly, jaundice, microencephaly, mental retardation, meningoencephalitis, radiolucent bone disease.Laboratory confirmation can be obtained by any of the following: virus isolation, serologi test (pasif hemaglutination, latex agglutinationtest, hemaglutination inhibisi, Flouresence immunoassay, Enzyme immunoassay), RNA test.
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Sulu, Ayse, Osman Baspinar, Selim Kervancıoglu, and Samil Hizli. "Giant Right Atrial Aneurysm Accompanying Intrahepatic Cholestasis." Case Reports in Cardiology 2018 (2018): 1–3. http://dx.doi.org/10.1155/2018/9025907.
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Right atrial aneurysms were first described in 1955, and subsequently, only a few cases have been reported. The etiology of this condition is unknown. Its comorbidity with cholestasis has not previously been reported in the literature. An 11-month-old baby female, who was an offspring from a first-cousin marriage, was referred to our hospital for investigation of jaundice. She underwent echocardiography because of a heart murmur, and this revealed a giant right atrial aneurysm. In addition, her liver biopsy confirmed the diagnosis of progressive familial intrahepatic cholestasis (PFIC) type 3. Although both conditions are rare, we found their comorbidity interesting and are thus reporting the case.
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Yousuf, Rabeya, Nor Fadzliana Abdullah Thalith, Yee Loong Tang, and Chooi Fun Leong. "Rh-D primigravida mother with anti Rh-17 antibodies causing mild haemolytic disease of foetus and newborn in baby: a case report." Bangladesh Journal of Medical Science 20, no. 3 (April 4, 2021): 669–72. http://dx.doi.org/10.3329/bjms.v20i3.52815.
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Rh-D is an unusual phenotype in Rh blood group system, lacking all Cc or Ee antigens but demonstrates a stronger D antigen expression. We describe here an extremely rare Rh-D phenotyped mother with first baby affected by haemolytic disease of foetus and newborn (HDFN). A 20-year-old pregnant lady, presented in active labour with foetal distress and planned for emergency cesarean section. Her blood group was A RhD positive, with positive antibody screening. Antibody identification demonstrated multiple antibodies against RhCc Ee polypeptide by the reference laboratory. Rh phenotype was -D-/-D- with no C/c and E/e antigen but strong D antigen. Crossmatch was incompatible with all A RhD positive units. Management of such patient is extremely difficult due to the scarcity of Rh-D- donor blood. In this case, reference laboratory had one frozen Rh-D- blood ready for use if indicated. Fortunately, patient underwent caesarean section without any complication. Baby was grouped as A Rh-D positive with probable Rh genotype as CDe/-D-. Baby’s DCT was positive and eluate showed antibodies of identical reactivity as mother. Baby developed mild jaundice at day-2 and managed with phototherapy. Clinically Rh-D- phenotype in pregnant women can cause mild to fatal HDFN. Routine antibody screening in pregnant women can detect such rare case that helps proper management of mother and baby. Prior arrangement of this rare blood is warranted to prevent the maternal and infant mortality and morbidity.
Bangladesh Journal of Medical Science Vol.20(3) 2021 p.669-672
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Sungkar, Ali, and Raymond Surya. "Rhesus incompatibility in pregnancy: a case report." Indonesian Journal of Perinatology 1, no. 1 (August 30, 2020): 1–4. http://dx.doi.org/10.51559/inajperinatol.v1i1.1.
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Introduction: Hemolytic disease of the fetus and newborn (HDFN) occurs due to the destruction of red blood cells, which the most common cause is rhesus incompatibility. This study aims to present a case of Rhesus incompatibility in pregnancy without a clinically significant effect on the baby.
Case: A-38-years-old Indonesian woman with gravida 4 para 3 (G4P3A0), 32 weeks of gestational age came to the emergency department due to vaginal bleeding. On blood typing, she had an A-negative (A-) blood type. Her husband and all three of their children had O-positive (O+) blood type. The patient underwent a cesarean section due to recurrent antepartum hemorrhage following the total placenta previa. She gave birth to a baby girl, weighed 2,220 grams with an A-positive blood type. The hemoglobin level was 14.6 g/dL without any sign of neonatal jaundice during the first 24 hours of life.
Conclusion: Our case illustrates a woman who did not show any sign of clinically Rhesus antigen alloimmunization. Low immunogenicity and dose-dependent response to a low fetal blood volume exposure might explain this phenomenon.
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Cruz, Déa Silvia Moura da, Zenilda Da Conceição Silva Sampaio, Daniela Karina Antão Marques, and Emanuel Nildivan Rodrigues da Fonseca. "Puerperal mothers: knowledge newborn jaundice." Revista de Enfermagem UFPE on line 6, no. 1 (December 11, 2011): 172. http://dx.doi.org/10.5205/reuol.2052-14823-1-le.0601201224.
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ABSTRACTObjective: to investigate the knowledge of puerperal mothers on neonatal jaundice in their own child. Method: this an exploratory and descriptive study with on qualiquantitative approach developed with the application of a questionnaire and through the following guiding questions:”What is the knowledge of puerperal mothers with regard to neonatal jaundice in their own child and its complications?”and “What is their satisfaction level with regard to the assistance provided by the nurse?”. It was carried out with ten puerperal mothers whose newly born babies were admitted to the Neonatal Intensive Care Unit of Maternidade Frei Damião in João Pessoa, Paraíba, Brazil, February and March 2011. The objective data were grouped and presented in absolute and relative numbers and the subjective questions were analyzed according to tehe Collective Subject Discourse (CSD) technique after the approval by the Research Ethics Committee of Faculdade de Enfermagem Nova Esperança (Facene), under the CAAE 0047.0.351.000 and the Protocol 228/10. Results: It was observed that the percentage of mothers under 21 years of age was considerable one (50%), most mothers had a good education level, considering that 5 (50%) had completed high school, and 1 (10%) had higher education; most mothers (70%) were primiparous. The CSD revealed that most mothers showed did not know the disease and its complications.Conclusion: the research led us to reflect on the need to change the strategies to improve the prenatal and postnatal assistance, preparing the mother for an effective care for her baby. Descriptors: bilirubin; knowledge; mothers.RESUMOObjetivo: investigar o conhecimento de puérperas em relação à icterícia neonatal no próprio filho. Método: trata-se estudo exploratório e descritivo, com abordagem qualiquantitativa, desenvolvido com a aplicação de um questionário a partir das seguintes questões norteadoras: “Qual é o conhecimento das puérperas com relação à icterícia neonatal no seu filho e suas complicações?” e “Qual o nível de satisfação delas em relação a assistência prestada pelo enfermeiro?. Foi realizado com dez puérperas que tiveram os recém-nascidos admitidos na Unidade de Terapia Intensiva Neonatal da Maternidade Frei Damião, em João Pessoa-PB, em fevereiro e março de 2011. Os dados objetivos foram agrupados e apresentados em números absolutos e relativos e as questões subjetivas foram analisadas de acordo com a técnica do Discurso do Sujeito Coletivo (DSC), após aprovação Comitê de Ética em Pesquisa da Faculdade de Enfermagem Nova Esperança (Facene), sob o CAAE n.0047.0.351.000-10 e o Protocolo n.228/10. Resultados: observou-se que o percentual das mães menores de 21 anos foi significativo (50%), a maioria das mães possuía um bom nível de escolaridade, considerando-se que 5 (50%) possuíam ensino médio completo e 1 (10%) ensino superior; maioria das mães (70%) era primípara. O DSC revelou que a maioria das mães desconhecia a doença e as suas complicações. Conclusão: a pesquisa levou a refletir quanto à necessidade de mudar as estratégias, para melhorar a assistência pré e pós-natal, preparando a mãe para um cuidado efetivo ao seu bebê. Descritores: bilirrubina; conhecimento; mães. RESUMENObjetivo: investigar el conocimiento de las madres puérperas con ralación a la ictericia neonatal en su proprio hijo. Método: esto es un estudio exploratorio y descriptivo con abordaje cualicuantitativo desarrollado con la aplicación de cuestionario y desde las siguientes cuestiones orientadoras:”Cuál es el conocimiento de las puérperas con relación a la ictericia neonatal en su hijo y sus complicaciones?” y “Cuál es el nivel de satisfacción de ellas con relación a la asistencia ofrecida por el enfermero?”.Fue realizado con diez mujeres que tuvieron sus hijos admitidos en la Unidad de Terapia Intensiva Neonatal de la Maternidade Frei Damião, en João Pessoa, Paraíba, Brazil en febrero y marzo de 2011. Los datos objetivos fueron agrupados y presentados en números absolutos y relativos y las cuestiones subjetivas fueron analizadas de acuerdo con la técnica del Discurso del Sujeto Colectivo (DSC) después de la aprobación del Comité de Ética en Investigación de la Faculdade de Enfermagem Nova Esperança (Facene) bajo el CAAE 0047.0.351.000 y el Protocolo 228/10. Resultados: se observó que el porcentaje de madres menores de 21 años fue significativo (50%), la mayoría de las madres tenía un buen nivel escolaridad, teniendo en cuenta que 5 (50%) habían terminado la escuela secundaria y 1(10 %) tenía enseñanza superior; la mayoría de las madres(70%) era primípara. El DSC reveló que la mayoría de las madres no conocia la enfermedad y sus complicaciones. Conclusión: la investigación nos ha hecho reflexionar acerca de la necesidad de cambiar las estrategias para mejorar la asistencia pre-y post-natal, preparando la madre para una atención efectiva a su bebé. Descriptores: bilirrubina; conocimiento; madres.
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Chu, Kuei-Hui, Shuh-Jen Sheu, Mei-Hwa Hsu, Jillian Liao, and Li-Yin Chien. "Breastfeeding Experiences of Taiwanese Mothers of Infants with Breastfeeding or Breast Milk Jaundice in Certified Baby-Friendly Hospitals." Asian Nursing Research 13, no. 2 (May 2019): 154–60. http://dx.doi.org/10.1016/j.anr.2019.04.003.
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Salariya, Ellena M., and Catherine M. Robertson. "Relationships between baby feeding types and patterns, gut transit time of meconium and the incidence of neonatal jaundice." Midwifery 9, no. 4 (December 1993): 235–42. http://dx.doi.org/10.1016/0266-6138(93)90007-f.
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Begum, Suraiya, Md Abdul Baki, Gopen Kundu, Imnul Islam, Manik Kumar Talukdar, and Kaniz Fatema. "Exchange Transfusion: Indication and Adverse Effect." Bangladesh Journal of Child Health 36, no. 1 (December 20, 2012): 16–19. http://dx.doi.org/10.3329/bjch.v36i1.13029.
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Objective: To determine the indication and complications of exchange transfusion (ET) performed for neonatal hyperbilirubinaemia. Methods: The medical records of infants < 28 days old who required exchange transfusion (ET) due to neonatal jaundice in Special Care Baby Unit (SCABU), BIRDEM hospital from January 2009 to April 2010 were retrospectively reviewed. Results: Exchange transfusion was performed in 30 neonates during the study period. Indications of exchange transfusion were ABO incompatibility (30.0%), Rh incompatibility (13.3%), septicaemia (6.6%) and in majority causes, were unidentified (50%). Most common complication were thrombocytopenia (33.3%) hyperkalaemia (20%), hypocalcaemia (16.7%) Conclusion: Indication of ET was unidentified in majority cases and among identified cases most common causes was ABO incompatibility. Adverse events were common after exchange transfusion.DOI: http://dx.doi.org/10.3329/bjch.v36i1.13029Bangladesh J Child Health 2012; Vol 36 (1): 16-19
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Stolyar, Helen, Teresa Berry, Amit Pal Singh, and Ichhcha Madan. "PIEZO1 mutation: a rare aetiology for fetal ascites." BMJ Case Reports 14, no. 4 (April 2021): e240682. http://dx.doi.org/10.1136/bcr-2020-240682.
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We present a case of isolated fetal ascites diagnosed at 20 weeks’ gestation. No aetiology was identified on extensive prenatal workup, including prenatal microarray. The patient terminated the pregnancy at 23 weeks’ gestation. Exome sequencing was performed on the products of conception, which ended up giving insight into a possible cause for the ascites. Two heterozygous missense variants of uncertain significance were identified in the PIEZO1 gene. The paternal variant has been linked to dehydrated hereditary stomatocytosis. The father of the baby suffers from haemolytic anaemia, splenomegaly and has had jaundice throughout his life. His brother and father have similar conditions. We suspect that at least one of the gene variants identified in our exome sequencing may be responsible for the illness that runs in this family, including the fetus with isolated ascites.
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Aljazaeri, Sarah Ali. "Neonatal Hyperbilirubinemia, Types, Causes and Treatments: A Review Study." Medical Science Journal for Advance Research 2, no. 2 (June 30, 2021): 76–79. http://dx.doi.org/10.46966/msjar.v2i2.23.
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Neonatal hyperbilirubinemia results from a readiness for the bilirubin production in neonates and limited their ability to excrete it. The diagnosis of hyperbilirubinemia based on yellow discoloration of the skin and whiteness of eyes, idle in the child's movement and the lack of lactation. The baby seems sick or is difficult to awaken. Bilirubin is a tetrapyrrole pigment derived from breakdown product of normal heme catabolism in senescent red blood cells. Unconjugated bilirubin normal elevation is named newborn physiologic hyperbilirubinemia, whereas the level of bilirubin of infant normally to be a bit higher after birth, In the same context the placenta in the womb of the mother. Pathologic hyperbilirubinemia is defined as odd of bilirubin from the normal level so intervention required. Many reasons for this type of jaundice
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Onyearugha, C. N., A. Chapp-Jumbo, and I. O. George. "Neonatal Jaundice: Evaluating the Knowledge and Practice of Expectant Mothers in Aba, Nigeria." Journal of Health Science Research 1, no. 2 (September 6, 2016): 42. http://dx.doi.org/10.18311/jhsr/2016/v1/i2/4918.
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<strong>Background:</strong> Neonatal jaundice is a foremost cause of hospitalization in the first week of life worldwide. If not properly managed, it may result in significant bilirubin-induced morbidity and mortality. <strong>Aim:</strong> To evaluate the knowledge and practice of expectant mothers towards neonatal jaundice (NNJ) in Aba, Nigeria. <strong>Materials and Methods:</strong> This was a questionnaire based study involving 300 expectant mothers during antenatal visit. Data was entered into a computer and descriptive analysis done using SPSS software version 17. <strong>Results:</strong> The respondents were aged 19 - 44 years, mean age, 29.2 ± 4.6 years. Two hundred and eighty eight (96%) were aware of NNJ, and 150 (50%) had health workers as their source of information. Most, 249 (83%) knew one site of recognition of NNJ. Only 24 (8%) knew one danger sign while 264 (88%) did not know any at all. Majority, 244 (81.3%) did not know any cause of NNJ. Only 30 (10%) knew appropriate treatment modality while only 42 (14%) would appropriately take a baby with NNJ immediately to hospital. <strong>Conclusion:</strong> There is paucity of knowledge on causes and danger signs of NNJ amongst expectant mothers in Aba. Health care providers should be encouraged to disseminate information on NNJ to the general population in places of worship, communal and social gatherings.
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Andrianirina, Zafitsara Z., Rosa L. Tsifiregna, Romuald Randriamahavonjy, and J. Bizet. "Atypical form of early neonatal infection with Salmonella enterica: case report with literature review." International Journal of Research in Medical Sciences 6, no. 5 (April 25, 2018): 1793. http://dx.doi.org/10.18203/2320-6012.ijrms20181486.
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Salmonella are rarely responsible for neonatal or perinatal infection. An annual incidence of 75/100000 births are reported in the USA. The authors present a case of a newborn with neonatal salmonellosis in the context of maternal infection in the days preceding the birth, documented retrospectively. This is a case of a 38-week male infant born via spontaneous vaginal delivery. There was a premature rupture of the membranes (13 hours). The mother gave a history of fever and diarrhea of ten days prior to delivery. She had fever of 38.3°C during labor. Prophylactic antibiotic treatment with amoxicillin was established. Thirty-two hours after birth, the baby developed fever, lethargy, and was not accepting feeds. On admission, physical examination showed fever, tachycardia, correct blood pressure and isolated jaundice. The blood count found a leukopenia, a thrombocytopenia, a CRP at 35mg/l. Parenteral antibiotic therapy with cefotaxime and amikacin was started. Apyrexia is obtained after 48 hours of intravenous treatment. Stool culture of the newborn grew after 48 hours and for the mother after 3 days. The germ identified was Salmonella enterica Serovar 4,5,12:i:-. Blood cultures were performed on the mothers and the baby, but the cultures were negative. The baby responded and was discharged on the 15th day of delivery. The mother’s condition was complicated by a Guillan Barré syndrome that required a transfer to neurology. Neonatal salmonellosis may have non-specific clinical symptoms. Management is based on early antibiotic therapy with a third-generation cephalosporin as first-line therapy. The measure in preventing the spread of infection in the neonatology is essential to avoid secondary cases.
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Sliusarieva, A. V. "ASSOCIATIONS BETWEEN MATERNAL METABOLIC RISK FACTORS AND BIRTH OF OVERWEIGHT PREMATURE BABY." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 21, no. 2 (June 17, 2021): 82–86. http://dx.doi.org/10.31718/2077-1096.21.2.82.
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The relative contribution of individual metabolic risk factors and their clusters in pregnant women to the birth of premature infants, who are too large for their gestational age, is not fully understood. The aim of this study is to find the correlation between individual metabolic risk factors and their clusters in pregnant women and the birth of premature newborns, which are too large for their gestational age. This retrospective study included 84 preterm infants. The following metabolic risk factors were assessed in mothers of the children: the presence of overweight / obesity before pregnancy, weight gain during pregnancy, high blood pressure during pregnancy, as well as the growing level of triglycerides immediately after childbirth, high-density lipoproteins, cholesterol, and hyperglycemia. Adverse effects in children included delivery route, neonatal asphyxia, respiratory failure syndrome, and jaundice. The odds ratios were calculated for both an individual metabolic risk factor and their combination using logistic regression analysis. Metabolic risk factors such as hypertension, diabetes and dyslipidemia were significantly associated with the birth of premature babies, who are too large for their gestational age after adjustment for other factors. In a cohort of premature babies, no reliable relationship was found between obesity and the birth of children, who are too large for their gestational age. Children whose mothers have three metabolic risk factors at the same time, as a rule, are more likely (OR = 7.39, 95% CI 2.72-20.11) to be born too large for their gestational age. Pregnant women with a combination of metabolic risk factors for preterm birth are more likely to give birth to babies, who are large for their gestational age.
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Shahwar, Durre, Sabina Ariff, Batha Tariq, Arjumand Rizvi, Syed Rehan, and Ali Shabbir Hussain. "EFFECTIVENESS OF TRANSCUTANEOUS BILIRUBIN (TCBR) MEASUREMENT IN HIGH RISK NEONATES AND TO EVALUATE THE VALIDITY OF TRANSCUTANEOUS BILIRUBIN (TCBR) WITH TOTAL SERUM BILIRUBIN (TSBR) LEVELS IN BOTH LOW AND HIGH RISK NEONATES AT A TERTIARY CARE CENTER OF...." PAFMJ 71, no. 1 (February 24, 2021): 357–63. http://dx.doi.org/10.51253/pafmj.v71i1.3853.
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Objective: To evaluate the utility of a Transcutaneous Bilirubin nomogram in high risk neonates and to evaluate the validity of Transcutaneous Bilirubin and Total serum bilirubin in both low and high-risk neonates.
Study Design: Cross-sectional study.
Place and Duration of Study: Postnatal Ward, Aga Khan University Hospital, Karachi, from May to Oct 2019.
Methodology: The participants will include all neonates born and admitted in the well baby nursery withjaundice. All neonates with gestational age of <35 weeks, requiring admission in Neonatal intensive care unit, and neonates with conjugated hyperbilirubinemia will be excluded. We will stratify our neonates into high and low risk population based on predefined criteria. Eighty five neonates in low risk group and 122 neonates in high risk group will be included.
Results: We aim to assess the effectiveness of Transcutaneous Bilirubin nomogram in high risk neonates asan effective and non-invasive tool in the management of neonatal jaundice in high risk neonates. We will alsoassess the sensitivity and specificity of Transcutaneous Bilirubin and Total serum bilirubin measurementsand the analysis would be performed separately for high risk and low risk neonates to evaluate the validity ofTranscutaneous Bilirubin independently in both groups.
Conclusion: We hope to establish a validated phototherapy guideline based on the Transcutaneous Bilirubinnomogram, as a cost effective and noninvasive tool in the management of neonatal jaundice in both high and low risk groups in Pakistan.
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Nazeer, Sirajuddin, Sivagurunathan Panchanathan, and Karthikeyan Soundararajan. "A prospective study comparing the morbidities of late preterm and term infants in the neonatal period in a tertiary care hospital." International Journal of Contemporary Pediatrics 8, no. 5 (April 27, 2021): 803. http://dx.doi.org/10.18203/2349-3291.ijcp20211666.
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Background: In obstetric practice, 34 completed weeks is considered as maturational milestone for the fetus. Despite relatively large size and apparent functional maturity, late preterm infants are at increased risk for neonatal morbidity compared with full term infants. Aim of the study was to study the incidence of late preterm births in a tertiary care hospital in Trichy, Tamil Nadu and to study the pattern of neonatal morbidities in late preterm infants and to compare it with term infants.Methods: Hospital based prospective study was conducted from April 2019 to March 2020. Total 470 late preterm infants were included in our study. All infants enrolled in the study were followed up daily till discharge and after discharge, all infants were than reviewed at 15 and 28 days in a well-baby clinic.Results: There were a total of 1941 live births during the study period. Of these, 470 (24.2%) were late preterm and 1263 (65%) were term births. Late preterm infants accounted for 71.1% of preterm birth. Late preterm infants were at significantly higher risk for overall morbidity due to any cause, respiratory 22.1%, neonatal jaundice 62%, sepsis 4%, hypoglycemia 8.9%, hospital readmission 8.1%. 63% of late preterm infants were readmitted for jaundice.Conclusions: The incidence of late preterm birth was 24%. Late preterm infants had a higher incidence of jaundice, sepsis and respiratory morbidities. Late preterm infants had a longer hospital stay. They were also more likely to get readmitted in the hospital when compared to term infants.
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Glassman, Melissa E., Rebekah Diamond, Sharon K. Won, Jasmyn Johal, and Dana R. Sirota. "Newborn Clinic: A Novel Model to Provide Timely, Comprehensive Care to Newborns Following Nursery Discharge." Clinical Pediatrics 59, no. 14 (October 1, 2020): 1233–39. http://dx.doi.org/10.1177/0009922820944400.
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Ensuring safe and timely follow-up after well baby nursery (WBN) discharge is an ongoing challenge. This study demonstrates the efficacy of a novel model for follow-up, the Newborn Clinic (NBC), in reducing time to outpatient follow-up after WBN discharge. Our retrospective chart review of 17 952 newborns found that time to follow-up visit decreased significantly following NBC establishment. Emergency department visits, a marker of infant morbidity, were slightly increased in the post-establishment cohort. There was no difference, however, in hospital readmissions. Analysis within the post-establishment cohort showed that newborns with jaundice, a high-risk group, were much more likely to have early follow-up if their visit was scheduled with NBC. Our study demonstrates that NBC is an effective model for decreasing time from WBN discharge to follow-up visit. It should be considered as an initiative to run concurrently with expedited newborn discharge initiatives so that safe follow-up need not be sacrificed.